Core capability for Chemistry Research
Lead Research Organisation:
Imperial College London
Department Name: Chemistry
Abstract
The National Importance of a vibrant and successful university Chemistry research sector cannot be underestimated. The RSC's report on the Economic Benefits of Chemistry showed that the UK's upstream chemicals industry and downstream chemistry-using sectors contributed a combined total of £258 billion in added-value in 2007, equivalent to 21% of UK GDP, and supported over 6 million UK jobs. This output is underpinned by some of the world's most successful University Chemistry research, reflecting the fruits of many years of investment. On-going fundamental research is essential, not only to maintain a continuing flow of scientific and technological breakthroughs, but also to ensure that the UK maintains a highly skilled and innovative workforce; it is through these trained people that the UK will adopt and advance new ideas, successfully exploit new technologies, and develop new and better products and services. The ability to develop and exploit chemically-derived technology will fuel economic activity, and is a necessary condition for attracting inward investment to the UK. The RSC report also showed that the quality of UK chemists and the reputation for excellence of the UK's university chemical science base significantly influences companies in decisions to locate within the UK, or to retain a UK-based research presence.
Imperial College is an internationally leading centre for research, education and translation. It is the only UK higher education institution to focus exclusively on science, engineering, medicine and business. The College is renowned both for world-class fundamental research and for the translation of this research to benefit society and the economy; this combination was indeed defined as a core part of the College's mission at its foundation in 1907. Its research strengths reflect its focus on fundamental underpinning science and cover the breadth of engineering and the physical sciences. The College currently holds 270 research grants totalling over £285M that have been through the EPSRC's peer review process; these include 11 Programme Grants and 12 Platform Grants.
The equipment requested is to underpin the above activity.
Imperial College is an internationally leading centre for research, education and translation. It is the only UK higher education institution to focus exclusively on science, engineering, medicine and business. The College is renowned both for world-class fundamental research and for the translation of this research to benefit society and the economy; this combination was indeed defined as a core part of the College's mission at its foundation in 1907. Its research strengths reflect its focus on fundamental underpinning science and cover the breadth of engineering and the physical sciences. The College currently holds 270 research grants totalling over £285M that have been through the EPSRC's peer review process; these include 11 Programme Grants and 12 Platform Grants.
The equipment requested is to underpin the above activity.
Planned Impact
Please see Pathways to Impact
Organisations
Publications
Boultwood T
(2014)
Synthesis and purification of iodoaziridines involving quantitative selection of the optimal stationary phase for chromatography.
in Journal of visualized experiments : JoVE
Pisaneschi F
(2014)
Synthesis of a new fluorine-18 glycosylated 'click' cyanoquinoline for the imaging of epidermal growth factor receptor.
in Journal of labelled compounds & radiopharmaceuticals
Zenzola M
(2015)
Synthesis of Sulfoximine Carbamates by Rhodium-Catalyzed Nitrene Transfer of Carbamates to Sulfoxides.
in The Journal of organic chemistry
Furse S
(2015)
Synthesis of unsaturated phosphatidylinositol 4-phosphates and the effects of substrate unsaturation on SopB phosphatase activity.
in Organic & biomolecular chemistry
Sung S
(2015)
Synthesis, characterisation and reactivity of copper(I) amide complexes and studies on their role in the modified Ullmann amination reaction.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Paterson I
(2015)
Synthetic studies toward the brasilinolides: controlled assembly of a protected C1-C38 polyol based on fragment union by complex aldol reactions.
in Organic & biomolecular chemistry
Douse C
(2014)
Targeting a Dynamic Protein-Protein Interaction: Fragment Screening against the Malaria Myosin A Motor Complex
in ChemMedChem
Mak LH
(2015)
Targeting PTEN using small molecule inhibitors.
in Methods (San Diego, Calif.)
Barriga HM
(2015)
Temperature and pressure tuneable swollen bicontinuous cubic phases approaching nature's length scales.
in Soft matter
Kumar S
(2016)
Template-Stripped Multifunctional Wedge and Pyramid Arrays for Magnetic Nanofocusing and Optical Sensing.
in ACS applied materials & interfaces
Bruno A
(2014)
Ternary hybrid systems of P3HT-CdSe-WS2 nanotubes for photovoltaic applications.
in Physical chemistry chemical physics : PCCP
Armstrong A
(2015)
Tertiary Amine Promoted Aziridination: Preparation of NH-Aziridines from Aliphatic a,ß-Unsaturated Ketones
in Synlett
Armstrong A
(2014)
Tertiary amine-promoted enone aziridination: investigations into factors influencing enantioselective induction
in Tetrahedron: Asymmetry
Barriga HM
(2016)
The effect of hydrostatic pressure on model membrane domain composition and lateral compressibility.
in Physical chemistry chemical physics : PCCP
Dou F
(2015)
The effect of phase morphology on the nature of long-lived charges in semiconductor polymer:fullerene systems
in Journal of Materials Chemistry C
Schrems A
(2014)
The grab-and-drop protocol: a novel strategy for membrane protein isolation and reconstitution from single cells.
in The Analyst
Shivalingam A
(2015)
The interactions between a small molecule and G-quadruplexes are visualized by fluorescence lifetime imaging microscopy.
in Nature communications
Lin Y
(2014)
The Pentynoate Ligand as a Building Block for Multimetallic Systems
in European Journal of Inorganic Chemistry
Ab Rani M
(2014)
The potential of methylsiloxanes as solvents for synthetic chemistry applications
in Green Chem.
Jenkins S
(2014)
The response of the electronic structure to electronic excitation and double bond torsion in fulvene: a combined QTAIM, stress tensor and MO perspective.
in Physical chemistry chemical physics : PCCP
Phanopoulos A
(2015)
The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphos Ph Complexes.
in Journal of visualized experiments : JoVE
López-Duarte I
(2015)
Thiophene-based dyes for probing membranes.
in Organic & biomolecular chemistry
Wang X
(2015)
Transient Absorption Spectroscopy of Anatase and Rutile: The Impact of Morphology and Phase on Photocatalytic Activity
in The Journal of Physical Chemistry C
Description | Chemistry is the study and application of the science at the molecular scale. It provides some of the most basic understandings of how the world works and underpins many modern technologies. It provides both the most mundane of objects, such as the disposable cup that holds you coffee, and the most vital compounds, such as life-saving drugs. Chemistry relies on four core instrumental techniques to study molecules; Nuclear Magnetic Resonance, Mass Spectrometry, X-Ray Crystallography and molecular scale Microscopy. This grant gave the Chemistry Department at Imperial College the ability to update these facilities. These have enabled research in all areas of Chemistry, for example the building of artificial cells, the production of fuels from biomass to the development of new potential pharmaceuticals and diagnostic techniques. There are too many to list. |
Exploitation Route | There are many ways in which these results can be put to use in the wider world. |
Sectors | Aerospace, Defence and Marine,Agriculture, Food and Drink,Chemicals,Energy,Environment,Healthcare,Manufacturing, including Industrial Biotechology,Culture, Heritage, Museums and Collections,Pharmaceuticals and Medical Biotechnology,Security and Diplomacy,Transport |
Description | Policy Briefing Document |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Author of policy briefing document: Using Carbon Dioxide |
Year(s) Of Engagement Activity | 2017 |
Description | Presentation to stakeholders |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Laura Barter was invited to the World Economic Forum in Davos to present her research investigating methods for increasing crop yields by promoting more efficient photosynthesis in the session on "Engineering Intelligent Food Systems". |
Year(s) Of Engagement Activity | 2018 |
Description | Radio Interview |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | BBC World Service's The Why Factor (8 February) on "Why is Water Exceptional?" |
Year(s) Of Engagement Activity | 2016 |
Description | Radio Interview |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Andrew Ashley interviewed on BBC Radio 4's Inside Science explaining his group's recent discovery in N2 fixation |
Year(s) Of Engagement Activity | 2016 |
Description | Schools activity |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Schools |
Results and Impact | Salters Festival of Chemistry: Annual Salters Festival. Y7 and Y8 many schools attend with their teachers to undertake two chemistry-based challenges |
Year(s) Of Engagement Activity | 2018 |
Description | Stakeholder meeting |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Laura Barter, Rudiger Wolcholski and Sarah Al-Beidh organised a Creativity and Ideas generation event for the Sainsbury's farming scholars which was also attended by Sainsbury's horticulture manager, academics from Imperial, Natural History Museum and other UK institutions. Followed by attending the Annual Sainsbury's Farming Conference to highlight the success of the Sainsbury's Farming Scholars Programme - a recent collaboration between Imperial College, AGRI-net and Sainsbury's. |
Year(s) Of Engagement Activity | 2015,2016 |
Description | UK Chemicals Stakeholder Forum. Presentation on measuring sustainability |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Policymakers/politicians |
Results and Impact | Presentation and discussion on sustainability metrics |
Year(s) Of Engagement Activity | 2016 |
Description | World Economic Forum meeting |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Policymakers/politicians |
Results and Impact | Prof David Klug introduced the "Hyperconnected Healthcare" panel at the World Economic Forum meeting in Dalian and participated as a panel member. |
Year(s) Of Engagement Activity | 2015 |