Refurbishment of the Herschel Smith building for Clinical Research in Cognitive Neuroscience at Cambridg University
Lead Research Organisation:
University of Cambridge
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
The University of Cambridge was awarded £617K towards refurbishment of the Herschel Smith building for Clinical Research in Cognitive Neuroscience, to provide a federated facility for translational cognitive neuroscience in the School of Clinical Medicine. The refurbishment will comprise: a clinical research facility (3 examination rooms, specialist testing facilities), office space for 52 people, two meeting rooms, ancillary facilities, and upgraded general infrastructure. The building will be used by cognate research groups representing the 4 major stakeholders in the project: the University Departments of Clinical Neurosciences and Psychiatry, the MRC Cognition & Brain Sciences Unit (CBU), and the MRC/Wellcome Trust Behavioural & Clinical Neurosciences Institute (BCNI)
Organisations
Publications
Mihalik A
(2020)
Multiple Holdouts With Stability: Improving the Generalizability of Machine Learning Analyses of Brain-Behavior Relationships.
in Biological psychiatry
Lynall ME
(2020)
Peripheral Blood Cell-Stratified Subgroups of Inflamed Depression.
in Biological psychiatry
Bullmore E
(2020)
Getting Below the Surface of Behavioral Symptoms in Psychiatry.
in Biological psychiatry
Bullmore ET
(2023)
Making Connections: Biological Mechanisms of Human Brain (Dys)connectivity.
in Biological psychiatry
Zhukovsky P
(2022)
Prefrontal Cortex Activation and Stopping Performance Underlie the Beneficial Effects of Atomoxetine on Response Inhibition in Healthy Volunteers and Those With Cocaine Use Disorder.
in Biological psychiatry. Cognitive neuroscience and neuroimaging
Schubert JJ
(2021)
A Modest Increase in 11C-PK11195-Positron Emission Tomography TSPO Binding in Depression Is Not Associated With Serum C-Reactive Protein or Body Mass Index.
in Biological psychiatry. Cognitive neuroscience and neuroimaging
Krystal JH
(2016)
Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature.
in Biological psychiatry. Cognitive neuroscience and neuroimaging
Morgan SE
(2021)
Functional Magnetic Resonance Imaging Connectivity Accurately Distinguishes Cases With Psychotic Disorders From Healthy Controls, Based on Cortical Features Associated With Brain Network Development.
in Biological psychiatry. Cognitive neuroscience and neuroimaging
Hampshire A
(2020)
Inhibition-Related Cortical Hypoconnectivity as a Candidate Vulnerability Marker for Obsessive-Compulsive Disorder
in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
Needham EJ
(2022)
Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses.
in Brain : a journal of neurology
Dutcher EG
(2020)
Early-life stress and inflammation: A systematic review of a key experimental approach in rodents.
in Brain and neuroscience advances
Chang JP
(2020)
Cortisol, inflammatory biomarkers and neurotrophins in children and adolescents with attention deficit hyperactivity disorder (ADHD) in Taiwan.
in Brain, behavior, and immunity
Kitzbichler M
(2021)
Peripheral inflammation is associated with micro-structural and functional connectivity changes in depression-related brain networks
in Brain, Behavior, and Immunity
Nikkheslat N
(2020)
Childhood trauma, HPA axis activity and antidepressant response in patients with depression.
in Brain, behavior, and immunity
Aruldass AR
(2021)
Dysconnectivity of a brain functional network was associated with blood inflammatory markers in depression.
in Brain, behavior, and immunity
Turkheimer FE
(2021)
Increased serum peripheral C-reactive protein is associated with reduced brain barriers permeability of TSPO radioligands in healthy volunteers and depressed patients: implications for inflammation and depression.
in Brain, behavior, and immunity
Lynall ME
(2021)
B-cells are abnormal in psychosocial stress and regulate meningeal myeloid cell activation.
in Brain, behavior, and immunity
Zhang Y
(2021)
The Human Brain Is Best Described as Being on a Female/Male Continuum: Evidence from a Neuroimaging Connectivity Study
in Cerebral Cortex
Quah SKL
(2022)
Higher-order brain regions show shifts in structural covariance in adolescent marmosets.
in Cerebral cortex (New York, N.Y. : 1991)
Olafson E
(2021)
Examining the Boundary Sharpness Coefficient as an Index of Cortical Microstructure in Autism Spectrum Disorder.
in Cerebral cortex (New York, N.Y. : 1991)
Török ME
(2021)
Challenges and opportunities for conducting a vaccine trial during the COVID-19 pandemic in the United Kingdom.
in Clinical trials (London, England)
Borsini A
(2020)
Characterizing anhedonia: A systematic review of neuroimaging across the subtypes of reward processing deficits in depression.
in Cognitive, affective & behavioral neuroscience
Hula A
(2021)
Multi-Round Trust Game Quantifies Inter-Individual Differences in Social Exchange from Adolescence to Adulthood.
in Computational psychiatry (Cambridge, Mass.)
Hampshire A
(2022)
Multivariate profile and acute-phase correlates of cognitive deficits in a COVID-19 hospitalised cohort.
in EClinicalMedicine
Stochl J
(2023)
Stratification of adolescents across mental phenomena emphasizes the importance of transdiagnostic distress: a replication in two general population cohorts.
in European child & adolescent psychiatry
Vanes LD
(2020)
White matter tract myelin maturation and its association with general psychopathology in adolescence and early adulthood.
in Human brain mapping
Mann C
(2021)
Examining volumetric gradients based on the frustum surface ratio in the brain in autism spectrum disorder.
in Human brain mapping
Bletsch A
(2021)
Atypical measures of diffusion at the gray-white matter boundary in autism spectrum disorder in adulthood.
in Human brain mapping
Ziegler G
(2020)
Childhood socio-economic disadvantage predicts reduced myelin growth across adolescence and young adulthood.
in Human brain mapping
Simpson-Kent I
(2021)
Bridging Brain and Cognition: A Multilayer Network Analysis of Brain Structural Covariance and General Intelligence in a Developmental Sample of Struggling Learners
in Journal of Intelligence
Chen S
(2020)
The early impact of COVID-19 on mental health and community physical health services and their patients' mortality in Cambridgeshire and Peterborough, UK
in Journal of Psychiatric Research
Giacobbe J
(2020)
The innate immune system and neurogenesis as modulating mechanisms of electroconvulsive therapy in pre-clinical studies.
in Journal of psychopharmacology (Oxford, England)
Bedford S
(2020)
Greater cortical thickness in individuals with ASD
in Molecular Psychiatry
Romero-Garcia R
(2019)
Synaptic and transcriptionally downregulated genes are associated with cortical thickness differences in autism.
in Molecular psychiatry
Kitzbichler MG
(2021)
Peripheral inflammation is associated with micro-structural and functional connectivity changes in depression-related brain networks.
in Molecular psychiatry
Bedford SA
(2020)
Large-scale analyses of the relationship between sex, age and intelligence quotient heterogeneity and cortical morphometry in autism spectrum disorder.
in Molecular psychiatry
Stauffer EM
(2021)
Grey and white matter microstructure is associated with polygenic risk for schizophrenia.
in Molecular psychiatry
Barbu MC
(2022)
Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system.
in Molecular psychiatry
Bethlehem RAI
(2022)
Brain charts for the human lifespan.
in Nature
Lynall ME
(2022)
Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells.
in Nature communications
Seidlitz J
(2020)
Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders.
in Nature communications
Reiter AMF
(2021)
Preference uncertainty accounts for developmental effects on susceptibility to peer influence in adolescence.
in Nature communications
Akarca D
(2021)
A generative network model of neurodevelopmental diversity in structural brain organization.
in Nature communications
Drevets W
(2022)
Immune targets for therapeutic development in depression: towards precision medicine
in Nature Reviews Drug Discovery
Zühlsdorff K
(2023)
Sex-dependent effects of early life stress on reinforcement learning and limbic cortico-striatal functional connectivity
in Neurobiology of Stress
Description | NHS and clinical research: HSB refurbishment |
Geographic Reach | Local/Municipal/Regional |
Policy Influence Type | Influenced training of practitioners or researchers |
Impact | Refurbishment of the Herchel Smith Building included provision of a bespoke clinical facility which has since been extensively used for specialist NHS clinics and experimental medicine research in neurology and psychiatry. |
Description | Treasurer, Academy of Medical Sciences |
Geographic Reach | National |
Policy Influence Type | Influenced training of practitioners or researchers |
Impact | The Academy of Medical Sciences (AMS) is the learned society that represents biomedical science in the UK with extensive portfolios of activity in policy, public engagement, and career development for clinical scientists. I have served as a member of Council of AMS since 2017 and as Treasure since 2019. |
URL | https://acmedsci.ac.uk/about/governance/honorary-officers |
Description | NIHR Biomedical Research Centre: HSB refurbishment |
Amount | £800,000 (GBP) |
Organisation | National Institute for Health Research |
Department | NIHR Cambridge Biomedical Research Centre |
Sector | Academic/University |
Country | United Kingdom |
Start | 04/2008 |
End | 03/2009 |
Description | The COVID-19 Clinical Neuroscience Study (COVID-CNS) |
Amount | £2,341,638 (GBP) |
Funding ID | MR/V03605X/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 10/2020 |
End | 04/2022 |
Description | University of Cambridge equipment funds |
Amount | £25,000 (GBP) |
Organisation | University of Cambridge |
Sector | Academic/University |
Country | United Kingdom |
Start | 10/2016 |
End | 02/2017 |