University of Birmingham – Continuing Confidence in Concept

Lead Research Organisation: University of Birmingham

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding.  It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.

Publications

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Carr HL (2020) New Developments in Transcriptomic Analysis of Synovial Tissue. in Frontiers in medicine

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Ismail MK (2020) Organometallic nucleoside analogues: effect of the metallocene metal atom on cancer cell line toxicity. in Dalton transactions (Cambridge, England : 2003)

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Mackenzie SW (2018) Ocular torsion responses to electrical vestibular stimulation in vestibular schwannoma. in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

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Patel AM (2021) The Role of B Cells in Adult and Paediatric Liver Injury. in Frontiers in immunology

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Schiffer L (2021) Peripheral blood mononuclear cells preferentially activate 11-oxygenated androgens. in European journal of endocrinology

 
Description DRAKE Foundation Award
Amount £170,316 (GBP)
Organisation University of Birmingham 
Sector Academic/University
Country United Kingdom
Start 01/2019 
 
Description Impact of chronic intermittent hypoxia on atrial resting membrane potential and Nav1.5 channel function: A new mechanism for causing atrial fibrillation
Amount £203,196 (GBP)
Funding ID PG/17/30/32961 
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2017 
End 07/2021
 
Description Instructive acellular tissue engineering (IATE)
Amount £273,280 (GBP)
Funding ID EP/S016589/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start 07/2019 
End 07/2021
 
Description MRC Confidence in Concept (Round 6)
Amount £46,964 (GBP)
Funding ID 21451 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 06/2018 
End 11/2020
 
Description MRC MR/R011230/1
Amount £1,849,101 (GBP)
Funding ID MR/R011230/1-MRC and MR/R011230/1-EQUIPM 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 09/2018 
End 10/2023
 
Description Rugby Football Union
Amount £26,000 (GBP)
Organisation University of Birmingham 
Sector Academic/University
Country United Kingdom
Start 07/2018 
 
Title ATRIAL FIBRILLATION THERAPY 
Description The present invention relates to methods of selectively determining suitable treatments for subjects suffering from atrial fibrillation, as well as a method of administering an antiarrhythmic drug to a subject and the use a sodium channel blocker, such as flecainide or propafenone to treat a specific cohort of patients with atrial fibrillation. The present invention is based upon studies carried out by the present inventors into the effect reduced pitx2c expression has on response to antiar 
IP Reference EP3120149 
Protection Patent granted
Year Protection Granted 2017
Licensed No
Impact n/a
 
Title BIOMARKERS OF TRAUMATIC BRAIN INJURY 
Description n/a 
IP Reference EP3426796 
Protection Patent application published
Year Protection Granted 2019
Licensed No
Impact n/a
 
Title COMPOSITION AND METHOD FOR BONE PRODUCTION 
Description The present invention relates to extracellular vesicles derived from osteoblasts or osteoblast-like cells, and in particular to their use in promoting bone growth and repair. 
IP Reference WO2018115871 
Protection Patent application published
Year Protection Granted 2018
Licensed No
Impact n/a