University of Birmingham – Continuing Confidence in Concept
Lead Research Organisation:
University of Birmingham
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding. It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.
Organisations
Publications
Azoidis I
(2018)
The role of extracellular vesicles in biomineralisation: current perspective and application in regenerative medicine.
in Journal of tissue engineering
Carr H
(2020)
New Developments in Transcriptomic Analysis of Synovial Tissue
in Frontiers in Medicine
Davies OG
(2017)
Annexin-enriched osteoblast-derived vesicles act as an extracellular site of mineral nucleation within developing stem cell cultures.
in Scientific reports
Hosie L
(2017)
Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8+ T-Cell Repertoire in Older People.
in Frontiers in immunology
Ismail M
(2020)
Organometallic nucleoside analogues: effect of the metallocene metal atom on cancer cell line toxicity
in Dalton Transactions
Ismail MK
(2020)
Effect of Regiochemistry and Methylation on the Anticancer Activity of a Ferrocene-Containing Organometallic Nucleoside Analogue.
in Chembiochem : a European journal of chemical biology
Mackenzie SW
(2018)
Ocular torsion responses to electrical vestibular stimulation in vestibular schwannoma.
in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Nikravesh N
(2019)
Physical Structuring of Injectable Polymeric Systems to Controllably Deliver Nanosized Extracellular Vesicles.
in Advanced healthcare materials
Patel AM
(2021)
The Role of B Cells in Adult and Paediatric Liver Injury.
in Frontiers in immunology
Schiffer L
(2021)
Peripheral blood mononuclear cells preferentially activate 11-oxygenated androgens.
in European journal of endocrinology
Description | DRAKE Foundation Award |
Amount | £170,316 (GBP) |
Organisation | University of Birmingham |
Sector | Academic/University |
Country | United Kingdom |
Start | 01/2019 |
Description | Developmental Pathway Funding Scheme |
Amount | £1,173,918 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2023 |
End | 02/2027 |
Description | Impact of chronic intermittent hypoxia on atrial resting membrane potential and Nav1.5 channel function: A new mechanism for causing atrial fibrillation |
Amount | £203,196 (GBP) |
Funding ID | PG/17/30/32961 |
Organisation | British Heart Foundation (BHF) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2017 |
End | 07/2021 |
Description | Instructive acellular tissue engineering (IATE) |
Amount | £273,280 (GBP) |
Funding ID | EP/S016589/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 07/2019 |
End | 07/2021 |
Description | Internally Funded PhD Studentship |
Amount | £45,000 (GBP) |
Organisation | University of Birmingham |
Sector | Academic/University |
Country | United Kingdom |
Start |
Description | MRC Confidence in Concept (Round 6) |
Amount | £46,964 (GBP) |
Funding ID | 21451 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 06/2018 |
End | 11/2020 |
Description | MRC MR/R011230/1 |
Amount | £1,849,101 (GBP) |
Funding ID | MR/R011230/1-MRC and MR/R011230/1-EQUIPM |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 09/2018 |
End | 10/2023 |
Description | Rugby Football Union |
Amount | £26,000 (GBP) |
Organisation | University of Birmingham |
Sector | Academic/University |
Country | United Kingdom |
Start | 07/2018 |
Title | ATRIAL FIBRILLATION THERAPY |
Description | The present invention relates to methods of selectively determining suitable treatments for subjects suffering from atrial fibrillation, as well as a method of administering an antiarrhythmic drug to a subject and the use a sodium channel blocker, such as flecainide or propafenone to treat a specific cohort of patients with atrial fibrillation. The present invention is based upon studies carried out by the present inventors into the effect reduced pitx2c expression has on response to antiar |
IP Reference | EP3120149 |
Protection | Patent granted |
Year Protection Granted | 2017 |
Licensed | No |
Impact | n/a |
Title | BIOMARKERS OF TRAUMATIC BRAIN INJURY |
Description | n/a |
IP Reference | EP3426796 |
Protection | Patent application published |
Year Protection Granted | 2019 |
Licensed | No |
Impact | n/a |
Title | COMPOSITION AND METHOD FOR BONE PRODUCTION |
Description | The present invention relates to extracellular vesicles derived from osteoblasts or osteoblast-like cells, and in particular to their use in promoting bone growth and repair. |
IP Reference | WO2018115871 |
Protection | Patent application published |
Year Protection Granted | 2018 |
Licensed | No |
Impact | n/a |
Title | SENSOR |
Description | The present invention relates to a genetic probe for the detection of a single nucleotide polymorphism (SNP) or a single nucleotide modification of a target nucleic acid, the genetic probe comprising: -a nanoparticle; -an oligonucleotide probe anchored to the surface of the nanoparticle, comprising an oligonucleotide backbone with a tag incorporated therein via a linker group; and -a reference probe anchored to the surface of the nanoparticle, wherein the reference probe comprises a marker; wherein either (a) the tag is an organic fluorescent tag and the marker is a transition metal-based fluorescent marker; or (b) the tag is a redox-active tag and the marker is a transition metal-based redox-active marker.The invention also relates to a composition or kit containing a probe of the invention, or to the use of a probe of the invention. The invention also relates to a method of determining the percentage of single nucleotide polymorphisms (SNPs) or single nucleotide modifications of a target nucleic acid in a pool of the target nucleic acid, or to a method of determining the status of a condition associated with a known SNP in a subject |
IP Reference | WO2019043353 |
Protection | Patent / Patent application |
Year Protection Granted | 2019 |
Licensed | No |
Impact | No impacts currently |