Maximising patient benefit: Leeds’ Interdisciplinary approach to translation (CiC 2016)
Lead Research Organisation:
University of Leeds
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding. It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.
Organisations
Publications
A Chakrabarty
(2019)
Temporal Artery Biopsy: Audit, Scoring and Reporting
Chakrabarty A
(2020)
Temporal artery biopsy: audit of histological diagnosis.
in Rheumatology (Oxford, England)
Chuter R
(2022)
A treatment planning comparison of photon stereotactic ablative radiotherapy and proton beam therapy for the re-irradiation of pelvic cancer recurrence.
in Physics and imaging in radiation oncology
Duncan JA
(2019)
The potential of memory enhancement through modulation of perineuronal nets.
in British journal of pharmacology
Irvine SF
(2018)
Perineuronal Nets in Spinal Motoneurones: Chondroitin Sulphate Proteoglycan around Alpha Motoneurones.
in International journal of molecular sciences
Koseki H
(2017)
Selective rab11 transport and the intrinsic regenerative ability of CNS axons.
in eLife
Mackie S
(2019)
102. PROPOSAL FOR A SYNOPTIC SYSTEM FOR REPORTING OF TEMPORAL ARTERY BIOPSIES
in Rheumatology
Murray L
(2023)
Treatment plan optimisation for reirradiation.
in Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Murray LJ
(2017)
Pelvic re-irradiation using stereotactic ablative radiotherapy (SABR): A systematic review.
in Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Nix M
(2022)
Dose summation and image registration strategies for radiobiologically and anatomically corrected dose accumulation in pelvic re-irradiation.
in Acta oncologica (Stockholm, Sweden)
Richter RP
(2018)
Glycosaminoglycans in extracellular matrix organisation: are concepts from soft matter physics key to understanding the formation of perineuronal nets?
in Current opinion in structural biology
Smith NJ
(2023)
Spatiotemporal microvascular changes following contusive spinal cord injury.
in Frontiers in neuroanatomy
Souter L
(2020)
Visualization of Perineuronal Nets in Central Nervous System Tissue Sections.
in Methods in molecular biology (Clifton, N.J.)
Tsatsanis A
(2019)
Post Translational Modulation of ß-Amyloid Precursor Protein Trafficking to the Cell Surface Alters Neuronal Iron Homeostasis.
in Neurochemical research
Van 't Spijker HM
(2017)
A Sweet Talk: The Molecular Systems of Perineuronal Nets in Controlling Neuronal Communication.
in Frontiers in integrative neuroscience
Van't Spijker HM
(2019)
Neuronal Pentraxin 2 Binds PNNs and Enhances PNN Formation.
in Neural plasticity
Walden M
(2019)
Metabolic control of BRISC-SHMT2 assembly regulates immune signalling.
in Nature
Warren P
(2017)
The Oxford Handbook of Developmental Neural Plasticity
Yang S
(2021)
Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing.
in Molecular psychiatry
Štepánková K
(2023)
4-Methylumbeliferone Treatment at a Dose of 1.2 g/kg/Day Is Safe for Long-Term Usage in Rats.
in International journal of molecular sciences
Description | CRUK RadNet |
Amount | £3,500,000 (GBP) |
Organisation | Cancer Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 11/2020 |
End | 10/2024 |
Description | Development of a small moledule inhibitor of Chst11 for restoration of cognition in Alzheimer's disease |
Amount | £60,000 (GBP) |
Funding ID | 1942167 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 06/2018 |
End | 05/2019 |
Description | Endothelial Piezo1 channel in whole body physical activity and cardio-metabolic protection |
Amount | £1,383,429 (GBP) |
Funding ID | RG/17/11/33042 |
Organisation | British Heart Foundation (BHF) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2018 |
End | 02/2023 |
Description | Funder: Leeds Cares, Leeds Hospitals Charity Scheme: Project grant |
Amount | £88,668 (GBP) |
Organisation | Leeds Cares |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 04/2021 |
End | 03/2022 |
Description | I-SMarD |
Amount | € 5,100,000 (EUR) |
Organisation | European Union |
Sector | Public |
Country | European Union (EU) |
Start | 04/2021 |
End | 03/2025 |
Description | IP Group with Grow Medtech Regulatory Study |
Amount | £120,000 (GBP) |
Organisation | Higher Education Funding Council for England |
Sector | Public |
Country | United Kingdom |
Start | 10/2018 |
End | 10/2020 |
Description | NA (Leeds Teaching Hospital award) |
Amount | £1,500 (GBP) |
Organisation | Leeds Hospitals Charity |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 11/2019 |
End | 11/2019 |
Description | Northern Triangle Initiative Award |
Amount | £10,000 (GBP) |
Organisation | Higher Education Funding Council for England |
Sector | Public |
Country | United Kingdom |
Start | 08/2018 |
End | 07/2019 |
Description | Potential oral treatment for spinal cord injury |
Amount | £28,000 (GBP) |
Organisation | End Paralysis Foundation |
Sector | Charity/Non Profit |
Country | Netherlands |
Start | 01/2021 |
End | 12/2022 |
Description | Recovery of normal breathing after chronic paralysis (Responsive Mode) |
Amount | £800,570 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 09/2019 |
End | 08/2022 |
Description | Stimulated Bone Regeneration |
Amount | £550,000 (GBP) |
Organisation | European Union |
Sector | Public |
Country | European Union (EU) |
Start | 01/2020 |
End | 12/2023 |
Description | University of Leeds Impact Accelerator Award |
Amount | £8,000 (GBP) |
Organisation | University of Leeds |
Sector | Academic/University |
Country | United Kingdom |
Start |
Description | UoL: MRC: Confidence in Concept A technology to improve efficiency of assessment of patients referred with suspected giant cell arteritis |
Amount | £13,786 (GBP) |
Organisation | Medical Research Council (MRC) |
Department | MRC Confidence in Concept Scheme |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2020 |
End | 02/2022 |
Description | Vasculitis UK. Project: TARGET Consortium Biobank |
Amount | £49,473 (GBP) |
Organisation | Vasculitis UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 02/2020 |
End | 07/2023 |