Newcastle Confidence in Concept 2016

Lead Research Organisation: Newcastle University

Abstract

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

Technical Summary

The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding.  It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.

Publications

10 25 50
 
Description AuToDeCRA 2 - Matching physiology to function: study autologous tolerogenic dendritic cell therapy focus on delivery route
Amount £1,106,921 (GBP)
Funding ID 21811 
Organisation Versus Arthritis 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2018 
End 07/2022
 
Description Confidence in Concept 2018 - New tools to image pulmonary embolism without exposure to ionising radiation
Amount £68,878 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 02/2020 
End 02/2021
 
Description EPSRC Impact Accelerator Award
Amount £45,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Public
Country United Kingdom
Start  
 
Description Investigating the antimicrobial activity of sphingosine as a novel therapy against respiratory infection in children
Amount £181,792 (GBP)
Organisation Newcastle upon Tyne Hospitals NHS Charity 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Investigation of replapsed Burkitt lymphoma
Amount £1,500 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Medimmune Grant
Amount £20,000 (GBP)
Funding ID 8300264934 
Organisation MedImmune Ltd 
Sector Private
Country United Kingdom
Start 05/2017 
End 05/2022
 
Description Microglia in the type I interferon system: protective and pathogenic mechanisms
Amount £412,853 (GBP)
Funding ID 211153 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2018 
End 11/2021
 
Description Personalised Therapies for all: Restoring airway function in CF using Alternative Chloride Channels
Amount £750,000 (GBP)
Organisation Cystic Fibrosis Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Precision medicine technologies: shaping the future - Point-of-care for stroke subtype diagnosis to enable rapid treatment
Amount £939,000 (GBP)
Organisation Innovate UK 
Sector Public
Country United Kingdom
Start  
 
Description Understanding the Properdin Paradox using C3 D1115N (gain-of-function) knock-in mice
Amount £569,241 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start  
 
Description Wellcome Trust ISSF - The role of tumour-infiltrating macrophages, dendritic cells, and T- regulatory cells in Classical Hodgkin lymphoma
Amount £9,261 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description i4i Innovative diagnostic test for early stage, high risk, melanoma AMLo
Amount £927,143 (GBP)
Funding ID II-LA-0417-20001 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 07/2018 
End 12/2020
 
Title Modified Complement Proteins and Uses Thereof 
Description The discovery relates to Pre-clinical evaluation of mini-FH derivatives to treat C3G and successful serum half-life extension of our minimal Factor H construct 
IP Reference WO2018197873 
Protection Patent application published
Year Protection Granted 2018
Licensed No
Impact It is hoped that this invention will make an impact in the field of kidney transplantation.