CiC#5: Furthering the potential for healthcare benefits from the University of Nottingham’s novel early-stage interdisciplinary biomedical research
Lead Research Organisation:
University of Nottingham
Department Name: UNLISTED
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Technical Summary
The Confidence in Concept scheme is a key part of MRC’s translational research strategy and provides annual awards to institutions, to be used flexibly to support the earliest stages of multiple translational research projects. The award can be used by the institution to support a number of preliminary-stage translational projects. The projects supported should aim to provide sufficient preliminary data to establish the viability of an approach –– before seeking more substantive funding. It is intended to accelerate the transition from discovery research to translational development projects by supporting preliminary work or feasibility studies to establish the viability of an approach.
Organisations
Publications
Anisimov N
(2021)
MRI Coils Optimized for Detection of 1H and 23Na at 0.5 T
in Applied Magnetic Resonance
Bayston R
(2019)
An external ventricular drainage catheter impregnated with rifampicin, trimethoprim and triclosan, with extended activity against MDR Gram-negative bacteria: an in vitro and in vivo study.
in The Journal of antimicrobial chemotherapy
Iglesias M
(2022)
Ensemble Kalman inversion for magnetic resonance elastography.
in Physics in medicine and biology
McGrath D
(2021)
In silico evaluation and optimisation of magnetic resonance elastography of the liver
in Physics in Medicine & Biology
McGrath DM
(2021)
In silicoevaluation and optimisation of magnetic resonance elastography of the liver.
in Physics in medicine and biology
Rostam H
(2020)
Immune-Instructive Polymers Control Macrophage Phenotype and Modulate the Foreign Body Response In Vivo
in Matter
Spencer GS
(2018)
Exploring the origins of EEG motion artefacts during simultaneous fMRI acquisition: Implications for motion artefact correction.
in NeuroImage
Description | A Feasibility Trial of Neuromodulation with Connectivity-Guided Intermittent Theta Burst Stimulation for Cognitive Impairment in MS |
Amount | £244,826 (GBP) |
Funding ID | Can specialised magnets improve cognition in MS? |
Organisation | Multiple Sclerosis Society |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 01/2020 |
End | 12/2022 |
Description | Development of renal Magnetic Resonance Elastography (MRE) for the assessment of kidney disease |
Amount | £49,081 (GBP) |
Organisation | Kidney Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2020 |
End | 03/2021 |
Description | Identification and Characterisation of the Phage and Host Receptors in Clostridium difficile, a Prequisite for Future Phage Therapies |
Amount | £37,000 (GBP) |
Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
Sector | Public |
Country | United Kingdom |
Start | 09/2018 |
End | 09/2022 |
Description | Miniaturized portable MRI sensors for healthcare applications |
Amount | £30,000 (GBP) |
Organisation | Russian Foundation for Basic Research |
Sector | Academic/University |
Country | Russian Federation |
Start |
Description | Towards miniaturised MRI based sodium sensors for healthcare applications |
Amount | £20,333 (GBP) |
Organisation | The Royal Society |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 12/2019 |
End | 12/2021 |
Title | ANTIBACTERIAL COMPOUNDS |
Description | Novel compounds having antimicrobial activitiy, in particular against Pseudomonas aeruginosa, Burkholderia cepaciaand/or Clostridium difficile, and a pharmaceutical composition containing the novel compound. |
IP Reference | WO2018167506 |
Protection | Patent application published |
Year Protection Granted | 2018 |
Licensed | No |
Impact | Has been awarded £2.05 miliion through the MRC DPFS scheme to translate the technology further |
Title | MATERIALS CHEMISTRIES AND MICROTOPOGRAPHIES AND USES THEREOF |
Description | A microtopography system for modulating one or more cellular processes on a surface is described. In particular a microtopography system comprising: a repeated microtopographic pattern and a polymer coating, said microtopographic pattern comprising: an array of repeated micropillars applied to a surface of a product, said micropillars being formed of surface structures between 1-100 µm in height, and 1-50 µm in width; and said polymer coating comprising one of a (meth)acrylate or (meth)acrylamide monomer, or mixture of two (meth)acrylate or (meth)acrylamide monomers.The microtopographic pattern and said polymer coating act to modulate one or more cellular processes on the surface. |
IP Reference | WO2021161290 |
Protection | Patent application published |
Year Protection Granted | 2021 |
Licensed | No |
Impact | None yet |