Capital award for UK DRI at Cardiff University
Lead Research Organisation:
CARDIFF UNIVERSITY
Department Name: UNLISTED
Abstract
Alongside significant co-investment from Cardiff University, the expected outcome of this funding is the conclusion of refurbishment of unoccupied office space in the Haydn Ellis Building building. Ground floor and 1st floor spaces have been set aside. The proposed layout is for approximately 60 researchers with short-term flexibility for further space and significant long-term capacity. For occupancy by end of May 2018.
Additionally, £2.5m for procurement of capital equipment is being provided to assist the UK DRI in implementing its first scientific programmes (funding provided separately).
Together, the building and equipment will provide the location for, in the initial stages of 3 programmes initially, to grow significantly in number in subsequent years. The UK DRI as a whole will help to cement the UK’s world-leading position by also promoting innovate approaches and forging much closer collaboration and integration of on-going UK research efforts. The new institute has been established to lead the UK’s dementia research effort and forms a core part of achieving the Prime Minister’s Challenge on Dementia 2020.
Additionally, £2.5m for procurement of capital equipment is being provided to assist the UK DRI in implementing its first scientific programmes (funding provided separately).
Together, the building and equipment will provide the location for, in the initial stages of 3 programmes initially, to grow significantly in number in subsequent years. The UK DRI as a whole will help to cement the UK’s world-leading position by also promoting innovate approaches and forging much closer collaboration and integration of on-going UK research efforts. The new institute has been established to lead the UK’s dementia research effort and forms a core part of achieving the Prime Minister’s Challenge on Dementia 2020.
Technical Summary
The aim of this award is to support Cardiff University with capital investment for setting-up of one of six UK Dementia Research Institute (UK DRI) centres; in particular, the capital required for building, refurbishment and the procurement of equipment.
At present, 3 programmes have been selected planned for the UK DRI at Cardiff University and with scientific and operational leadership provided by its associate director, Professor Julie Williams. The project at Cardiff University will involve refurbishment of unoccupied office space in the Haydn Ellis Building building. Ground floor and 1st floor spaces have been set aside. The proposed layout is for approximately 60 researchers with short-term flexibility for further space and significant long-term capacity. For occupancy by end of May 2018.
The approach of the institute as a whole, of which the UK DRI at Cardiff University forms a core part, is to amplify and enhance, not replace, current dementia research efforts in the UK. The UK DRI will help to cement the UK’s world-leading position by supplying vital new funding for research, coupled to promoting innovate approaches and forging much closer collaboration and integration of on-going UK research efforts.
There is a gap in our knowledge of how the healthy brain functions and what leads to its degeneration. The UK DRI will fill this crucial gap that exists at the start of the dementia research journey. It will study the healthy brain and neurodegeneration in order to build new knowledge and understanding that will lead to new treatments. It will also proactively connect to existing clinical and population-level dementia initiatives – for example as being undertaken by the MRC Dementias Platform UK and through the NIHR TRC-D – to catalyse a unique national and strategic approach to confronting the dementia challenge.
In particular, the present research at the UK DRI at Cardiff University plans to look at the synapse loss and cell death in AD; How AD risk genes affect microglial production & activation ; Cross-DRI programmes: novel mathematical and statistical approaches and models to stratify dementia risk and identify patterns in large ‘omics’ datasets.. Funding to these science programmes is provided separately.
At present, 3 programmes have been selected planned for the UK DRI at Cardiff University and with scientific and operational leadership provided by its associate director, Professor Julie Williams. The project at Cardiff University will involve refurbishment of unoccupied office space in the Haydn Ellis Building building. Ground floor and 1st floor spaces have been set aside. The proposed layout is for approximately 60 researchers with short-term flexibility for further space and significant long-term capacity. For occupancy by end of May 2018.
The approach of the institute as a whole, of which the UK DRI at Cardiff University forms a core part, is to amplify and enhance, not replace, current dementia research efforts in the UK. The UK DRI will help to cement the UK’s world-leading position by supplying vital new funding for research, coupled to promoting innovate approaches and forging much closer collaboration and integration of on-going UK research efforts.
There is a gap in our knowledge of how the healthy brain functions and what leads to its degeneration. The UK DRI will fill this crucial gap that exists at the start of the dementia research journey. It will study the healthy brain and neurodegeneration in order to build new knowledge and understanding that will lead to new treatments. It will also proactively connect to existing clinical and population-level dementia initiatives – for example as being undertaken by the MRC Dementias Platform UK and through the NIHR TRC-D – to catalyse a unique national and strategic approach to confronting the dementia challenge.
In particular, the present research at the UK DRI at Cardiff University plans to look at the synapse loss and cell death in AD; How AD risk genes affect microglial production & activation ; Cross-DRI programmes: novel mathematical and statistical approaches and models to stratify dementia risk and identify patterns in large ‘omics’ datasets.. Funding to these science programmes is provided separately.
Organisations
- CARDIFF UNIVERSITY (Lead Research Organisation)
- University College London (Collaboration)
- VU University Medical Center (Collaboration)
- University of Pennsylvania (Collaboration)
- National Institute of Health and Medical Research (INSERM) (Collaboration)
- Pasteur Institute, Lille (Collaboration)
- Erasmus MC (Collaboration)
- Hospital de Sant Pau (Collaboration)
- IMPERIAL COLLEGE LONDON (Collaboration)
- University of Bonn (Collaboration)
- KING'S COLLEGE LONDON (Collaboration)
- UNIVERSITY OF EXETER (Collaboration)
People |
ORCID iD |
Julie Williams (Principal Investigator) |
Publications
Huang KL
(2017)
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.
in Nature neuroscience
Sims R
(2017)
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
in Nature genetics
Ahmad S
(2018)
Disentangling the biological pathways involved in early features of Alzheimer's disease in the Rotterdam Study.
in Alzheimer's & dementia : the journal of the Alzheimer's Association
Leonenko G
(2019)
Polygenic risk and hazard scores for Alzheimer's disease prediction.
in Annals of clinical and translational neurology
Leonenko G
(2019)
Genetic risk for alzheimer disease is distinct from genetic risk for amyloid deposition.
in Annals of neurology
Lancaster TM
(2019)
Microglia - mediated immunity partly contributes to the genetic association between Alzheimer's disease and hippocampal volume.
in Brain, behavior, and immunity
Description | Academy Medical Sciences Council Member |
Geographic Reach | National |
Policy Influence Type | Membership of a guideline committee |
Description | Academy Medical Sciences Fellow |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Membership of a guideline committee |
Description | Academy Medical Sciences Wales Ambassador |
Geographic Reach | National |
Policy Influence Type | Membership of a guideline committee |
Description | Associate Director, UK Dementia Research Institute (UKDRI) |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Membership of a guideline committee |
Description | COVID advisory group |
Geographic Reach | National |
Policy Influence Type | Membership of a guideline committee |
Description | Chief Scientific Advisor, Welsh Government |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Membership of a guideline committee |
Description | EPAD LCS sample access committe |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Membership of a guideline committee |
Description | Medicines Discovery Institute MDI |
Geographic Reach | National |
Policy Influence Type | Membership of a guideline committee |
Description | NMHRI management |
Geographic Reach | National |
Policy Influence Type | Membership of a guideline committee |
Description | Exploration of inflammatory APOE44 astrocytic phenotypes |
Amount | £29,723 (GBP) |
Funding ID | 5245665 |
Organisation | Alzheimer's Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2023 |
End | 02/2024 |
Description | MRC World Class Labs Capital Funding 2023/24 |
Amount | £54,000 (GBP) |
Funding ID | 526618 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 12/2023 |
End | 03/2024 |
Description | The Moondance Dementia Research Laboratory |
Amount | £5,000,000 (GBP) |
Funding ID | 525036 |
Organisation | The Moondance Foundation |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2023 |
End | 08/2028 |
Description | The development and implementation of polygenic risk algorithms for stratifying individuals for future cognitive decline due to Alzheimers disease |
Amount | £298,040 (GBP) |
Funding ID | 2018/20180222 |
Organisation | Innovate UK |
Sector | Public |
Country | United Kingdom |
Start | 03/2018 |
End | 03/2020 |
Description | The impact of AD-associated risk variants in complement genes on neurodegeneration |
Amount | £271,303 (GBP) |
Funding ID | 523088 |
Organisation | Alzheimer's Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2023 |
End | 09/2026 |
Description | UKDRI Core Budget - Project 1 |
Amount | £1,686,147 (GBP) |
Funding ID | 524209 |
Organisation | UK Dementia Research Institute |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2023 |
End | 03/2028 |
Description | UKDRI Core Budget - Project 2 |
Amount | £1,547,766 (GBP) |
Funding ID | 524210 |
Organisation | UK Dementia Research Institute |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2023 |
End | 03/2024 |
Title | AD Genetics Scotland |
Description | Blood samples are collected from participants and sent directly from research sites to European Collection of Authenticated Cell Cultures (ECACC), a Culture Collection of Public Health England. Upon arrival, ECACC process the blood and transform into cell lines- peripheral blood lymphocytes (PBLs) and Lymphoblastoid cell lines (LCLs). Cell lines are frozen and stored at ECACC until they are required by the team at Cardiff. |
Type Of Material | Biological samples |
Year Produced | 2018 |
Provided To Others? | No |
Impact | Ongoing collection of samples, no publications to date. |
Title | DLB Genetics |
Description | Blood samples are collected from participants and sent directly from research sites to European Collection of Authenticated Cell Cultures (ECACC), a Culture Collection of Public Health England. Upon arrival, ECACC process the blood and transform into cell lines- peripheral blood lymphocytes (PBLs) and Lymphoblastoid cell lines (LCLs). Cell lines are frozen and stored at ECACC until they are required by the team at Cardiff |
Type Of Material | Biological samples |
Year Produced | 2018 |
Provided To Others? | No |
Impact | Ongoing collection of samples, no publications to date |
Title | Plcg2 animal models |
Description | To establish a functional pipeline for the study of disease associated genes and polymorphism in microglia and MØ in the context of dementia-related disease in vivo. The initial concentration is on the impact of coding mutations of PLCG2. In parallel, studies were initated on SPI1 and ABI3. Large scale 'omic and functional assay data derived from these studies will be used to bioinformatically identify potential causative abnormalities, by association with patient data |
Type Of Material | Model of mechanisms or symptoms - mammalian in vivo |
Year Produced | 2018 |
Provided To Others? | No |
Impact | n/a |
Description | ADES Collaboration |
Organisation | Erasmus MC |
Country | Netherlands |
Sector | Hospitals |
PI Contribution | A way to make aware our different institutions and funders of that we are working hard to a better organisation of the AD genetic field worldwide and we need strong support for this. |
Collaborator Contribution | as above |
Impact | n/a |
Start Year | 2016 |
Description | ADES Collaboration |
Organisation | Hospital de Sant Pau |
Country | Spain |
Sector | Hospitals |
PI Contribution | A way to make aware our different institutions and funders of that we are working hard to a better organisation of the AD genetic field worldwide and we need strong support for this. |
Collaborator Contribution | as above |
Impact | n/a |
Start Year | 2016 |
Description | ADES Collaboration |
Organisation | National Institute of Health and Medical Research (INSERM) |
Country | France |
Sector | Academic/University |
PI Contribution | A way to make aware our different institutions and funders of that we are working hard to a better organisation of the AD genetic field worldwide and we need strong support for this. |
Collaborator Contribution | as above |
Impact | n/a |
Start Year | 2016 |
Description | ADES Collaboration |
Organisation | Pasteur Institute, Lille |
Country | France |
Sector | Charity/Non Profit |
PI Contribution | A way to make aware our different institutions and funders of that we are working hard to a better organisation of the AD genetic field worldwide and we need strong support for this. |
Collaborator Contribution | as above |
Impact | n/a |
Start Year | 2016 |
Description | ADES Collaboration |
Organisation | University College London |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | A way to make aware our different institutions and funders of that we are working hard to a better organisation of the AD genetic field worldwide and we need strong support for this. |
Collaborator Contribution | as above |
Impact | n/a |
Start Year | 2016 |
Description | ADES Collaboration |
Organisation | University of Bonn |
Country | Germany |
Sector | Academic/University |
PI Contribution | A way to make aware our different institutions and funders of that we are working hard to a better organisation of the AD genetic field worldwide and we need strong support for this. |
Collaborator Contribution | as above |
Impact | n/a |
Start Year | 2016 |
Description | ADES Collaboration |
Organisation | University of Pennsylvania |
Country | United States |
Sector | Academic/University |
PI Contribution | A way to make aware our different institutions and funders of that we are working hard to a better organisation of the AD genetic field worldwide and we need strong support for this. |
Collaborator Contribution | as above |
Impact | n/a |
Start Year | 2016 |
Description | ADES Collaboration |
Organisation | VU University Medical Center |
Country | Netherlands |
Sector | Academic/University |
PI Contribution | A way to make aware our different institutions and funders of that we are working hard to a better organisation of the AD genetic field worldwide and we need strong support for this. |
Collaborator Contribution | as above |
Impact | n/a |
Start Year | 2016 |
Description | PROTECT / CHARIOT-Pro / Cardiff DPUK |
Organisation | Imperial College London |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | Genotyping of 1,000 research participants from the PROTECT (KCL & Exeter) and CHARIOT - Pro (Imperial) research studies will be completed by Cardiff Univ as part of a collaboration funded by Dementias Platform UK. Polygenic risk scores will be calculated for these individuals and data made available via DPUK Platform. |
Collaborator Contribution | DNA samples from 1,000 research participants from the PROTECT (KCL & Exeter) and CHARIOT - Pro (Imperial) research studies will be sent to Cardiff Univ for genotyping |
Impact | None to date - work in progress. Collaboration is multi-disciplinary - Neurology, Neuroepidemiology & Ageing; Genetics & Genomics; Psychiatry |
Start Year | 2018 |
Description | PROTECT / CHARIOT-Pro / Cardiff DPUK |
Organisation | King's College London |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | Genotyping of 1,000 research participants from the PROTECT (KCL & Exeter) and CHARIOT - Pro (Imperial) research studies will be completed by Cardiff Univ as part of a collaboration funded by Dementias Platform UK. Polygenic risk scores will be calculated for these individuals and data made available via DPUK Platform. |
Collaborator Contribution | DNA samples from 1,000 research participants from the PROTECT (KCL & Exeter) and CHARIOT - Pro (Imperial) research studies will be sent to Cardiff Univ for genotyping |
Impact | None to date - work in progress. Collaboration is multi-disciplinary - Neurology, Neuroepidemiology & Ageing; Genetics & Genomics; Psychiatry |
Start Year | 2018 |
Description | PROTECT / CHARIOT-Pro / Cardiff DPUK |
Organisation | University of Exeter |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | Genotyping of 1,000 research participants from the PROTECT (KCL & Exeter) and CHARIOT - Pro (Imperial) research studies will be completed by Cardiff Univ as part of a collaboration funded by Dementias Platform UK. Polygenic risk scores will be calculated for these individuals and data made available via DPUK Platform. |
Collaborator Contribution | DNA samples from 1,000 research participants from the PROTECT (KCL & Exeter) and CHARIOT - Pro (Imperial) research studies will be sent to Cardiff Univ for genotyping |
Impact | None to date - work in progress. Collaboration is multi-disciplinary - Neurology, Neuroepidemiology & Ageing; Genetics & Genomics; Psychiatry |
Start Year | 2018 |
Title | genoSCORE |
Description | Cytox Ltd, which provides non-invasive, risk assessment and patient stratification tools for Alzheimer's disease and dementia, has signed a license agreement with Cardiff University to access the University's Intellectual Property regarding polygenic risk scoring algorithms for predicting the future onset of Alzheimer's disease. Under the terms of the licence, Cytox will gain exclusive commercialisation rights to intellectual property (IP) and know-how generated under its ongoing collaboration with Cardiff University. Additionally, Cytox will gain non-exclusive rights to further IP from Cardiff University. Cytox is incorporating the technology defined within the licence in the development of genoSCORETM, a genetic risk assessment tool to Identify people at risk of developing Alzheimer's disease. genoSCORE improves clinical trial patient recruitment enrichment to Alzheimer's disease clinical studies; it also aids physicians in the management of patients in clinical practice. Cytox expects to launch genoSCORE as a product registered for professional use in the US and Europe, towards the end of 2020. |
IP Reference | |
Protection | Trade Mark |
Year Protection Granted | 2020 |
Licensed | Commercial In Confidence |
Impact | None to date - licence signed Sept 2020 |
Description | AAIC Los Angeles Annual Conference |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | MODEL-AD presentation - Alzheimer's Susceptibility Genes Implicate Microglial Activity |
Year(s) Of Engagement Activity | 2019 |
Description | AMS fellowship workshop |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other audiences |
Results and Impact | Organisation of a Academy of Medical Science workshop by J Williams as Wales AMS Champion to encourage applications from young researchers to become AMS fellows |
Year(s) Of Engagement Activity | 2019 |
Description | ARUK Conference |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Attendee at online conference |
Year(s) Of Engagement Activity | 2022 |
Description | ARUK network 2019 Exeter |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other audiences |
Results and Impact | The event was organised between the ARUK Bristol & Bath, Southwest (Exeter and Plymouth) and Wales networks. The aim was for members to meet, showcase research & build collaborations. J Williams spoke on Research infrastructure and resources: UKDRI as member of Cardiff University and UK Brain Banks Network |
Year(s) Of Engagement Activity | 2019 |
Description | Alzheimer's gene study achieves landmark breakthrough |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Cardiff University publicised publication in Nature Genetics "Genetic meta-analysis of diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing" - aiming to raise public awareness of research being undertaken at UK Dementia Research Institute Cardiff |
Year(s) Of Engagement Activity | 2019 |
Description | BBC Wales evening news UK DRI Cardiff official opening |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Public/other audiences |
Results and Impact | Interview of Professor Julie Williams to publicise official opening of UK DRI Cardiff. Prof Williams explained the purpose of the DRI, its multi-targeted approach, and the funding that had enabled attraction of world class scientists to Cardiff. |
Year(s) Of Engagement Activity | 2018 |
URL | https://www.bbc.co.uk/iplayer/episode/b0bp0k0t/bbc-wales-today-evening-news-25102018# |
Description | BBC news article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Patients, carers and/or patient groups |
Results and Impact | Talk - Alzheimer's disease: Experts hope for treatment by 2040 |
Year(s) Of Engagement Activity | 2023 |
Description | Best Paper of 2022 meeting |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Meeting to discuss paper that was deemed the best of 2022 |
Year(s) Of Engagement Activity | 2022 |
Description | Brain Conference |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Industry/Business |
Results and Impact | The Guarantors of Brain was set up to promote teaching, education and research in neurology and related disciplines. In 2021, we put on our first conference - run as a 2-day online conference, with a focus on clinical neurology and research. The conference was attended by almost 2000 delegates across the globe. |
Year(s) Of Engagement Activity | 2022 |
Description | Brain Conference |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Industry/Business |
Results and Impact | Invited speaker |
Year(s) Of Engagement Activity | 2022 |
Description | CURE ND Workshop |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Workshop to discuss disease models in the field of neurodegeneration, what are the most advanced models to date, how accurate are they, and what is missing in terms of modelling |
Year(s) Of Engagement Activity | 2021 |
Description | Cheltenham Science Festival |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | The Festival theme 2019 was health and wellbeing, considering everything from the food we eat and our exercise regimes to cutting-edge medical research. As part of this theme, the event explored the latest breakthroughs in dementia research. The panel was asked to talk about the broad landscape in this field and its evolution in recent years, key achievements and challenges and an insight into how the diagnosis and treatment of dementia has changed and developed. J Williams talked about cutting-edge research and expertise and the exciting aspects of her own work within this area As populations have aged, dementia has become the fifth biggest cause of death worldwide. Yet despite its devastating consequences there is currently no cure. What do we know about this group of diseases, and are there things we can do to help reduce our risks and keep our brains fighting fit? Alzheimer's disease specialist Julie Williams and psychiatrist Ivan Koychev discuss the latest breakthroughs and discoveries that are helping to prevent, diagnose and treat dementia more effectively. |
Year(s) Of Engagement Activity | 2011,2019 |
Description | Insurance United Against Dementia |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Supporters |
Results and Impact | Alzheimer's Society Insurance United Against Dementia campaign dinner - aim to formally launch IUAD partners to senior figureheads from the insurance industry Used as an opportunity to thank existing IUAD partners and inspire potential partners to make a contribution. |
Year(s) Of Engagement Activity | 2019 |
Description | Interview |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Dementia series interview - Dementia : Hope for the future (broadcast 12/12/23) |
Year(s) Of Engagement Activity | 2023 |
Description | Interview |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Podcast Naked Scientist https://www.thenakedscientists.com/podcasts/naked-scientists-podcast/titans-science-julie-williams?utm_source=campaign-plugin&utm_medium=email&utm_campaign=24-01-31%20UK%20DRI%20General%20bulletin |
Year(s) Of Engagement Activity | 2024 |
Description | Interview for national news |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Wales this week - ITV Wales https://www.itv.com/walesprogrammes/articles/wales-this-week-dementia-in-loving-memory |
Year(s) Of Engagement Activity | 2024 |
Description | Interview for national news |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Comments on article in Daily Telegraph - When forgetfulness becomes something more sinister, Sunday Mirror Magazine - Fiona Phillips |
Year(s) Of Engagement Activity | 2023 |
Description | Interview for national news |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Interview for BBC Wales on Donemab story |
Year(s) Of Engagement Activity | 2023 |
Description | Interview with Adrian Masters face to face programme |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other audiences |
Results and Impact | Face to face interview with ITV Cymru Wales |
Year(s) Of Engagement Activity | 2023 |
Description | Interview with BBC |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Interview with BBC - Alzheimer's article |
Year(s) Of Engagement Activity | 2022 |
Description | MRC CNGG celebration event |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | MRC CNGG celebration - presentation and video |
Year(s) Of Engagement Activity | 2019 |
Description | RCPsych Neuropsychiatry Annual Conference 2019 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Professional Practitioners |
Results and Impact | Talk given to conference entitled "Neuropsychiatric Genetics of Dementia and other Neurodegenerative Disorders: Implications for treatment, prevention and personalised psychiatry" |
Year(s) Of Engagement Activity | 2019 |
Description | Radio Interview with Alz Res UK Champion |
Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Public/other audiences |
Results and Impact | Radio Gloucester interview with Sue Strachan Alz Res UK Champion |
Year(s) Of Engagement Activity | 2021 |
Description | Radio interview |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Radio 4 interview for the programme The Life Scientific |
Year(s) Of Engagement Activity | 2023 |
Description | Taking a new look at the risk factors for Alzheimer's disease |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Public/other audiences |
Results and Impact | Media article on publication of Multiplex Model in Nature Neuroscience - providing information on how the genes that have been identified as risk factors impact on other genes to trigger Alzheimer's |
Year(s) Of Engagement Activity | 2020 |
Description | Techniquest 55+Science Cafe Launch |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Supporters |
Results and Impact | Invited speaker |
Year(s) Of Engagement Activity | 2022 |
Description | UK Biobank Winter Scientific Conference |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Invited speaker to conference in London |
Year(s) Of Engagement Activity | 2022 |
Description | UK Korea Neuroscience Symposium |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | UKorea symposia bridge basic and clinical research within neuroscience. J Williams gave plenary lecture on 1st day 2019 symposium. The statements were shared via the UK-Korea social media channel (twitter @UKorea_Neuro). |
Year(s) Of Engagement Activity | 2019 |
Description | Virtual UK DRI showcase event |
Form Of Engagement Activity | Engagement focused website, blog or social media channel |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Industry/Business |
Results and Impact | Virtual UK DRI showcase event aimed at industry and investors - to stimulate partnership and investment |
Year(s) Of Engagement Activity | 2020 |
Description | Visit by Lord Mayor of Cardiff to DRI |
Form Of Engagement Activity | Participation in an open day or visit at my research institution |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Other audiences |
Results and Impact | Visit by Lord Mayor of Cardiff to Dementia Research Institute |
Year(s) Of Engagement Activity | 2022 |
Description | Visit by Ruth Jones MP to DRi |
Form Of Engagement Activity | Participation in an open day or visit at my research institution |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Other audiences |
Results and Impact | Ruth Jones MP visited Dementia Research Institute Cardiff |
Year(s) Of Engagement Activity | 2022 |
Description | Visit of Jo Stephens MP to DRI |
Form Of Engagement Activity | Participation in an open day or visit at my research institution |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Other audiences |
Results and Impact | Visit by Jo Stephens MP to Cardiff Dementia Research Institute |
Year(s) Of Engagement Activity | 2022 |
Description | Visit to DRI laboratories by Sir Venki Ramakrishnan |
Form Of Engagement Activity | Participation in an open day or visit at my research institution |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Other audiences |
Results and Impact | Sir Venki Ramakrishnan, the President of the Royal Society visited DRI laboratories, Cardiff on 23rd October prior to giving a lecture organised by Welsh Government |
Year(s) Of Engagement Activity | 2019 |
Description | Welsh Government AM visit |
Form Of Engagement Activity | Participation in an open day or visit at my research institution |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Policymakers/politicians |
Results and Impact | Visit from Suzy Davies AM for tour of DRI offices and laboratories, meeting with all programme leads to discuss work undertaken |
Year(s) Of Engagement Activity | 2019 |
Description | Welsh Government workshop |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Policymakers/politicians |
Results and Impact | The Welsh Government held a UKRI "Strength in Places Fund" and potential for Wales workshop. Strength in Places (SIP) offers a significant funding opportunity and the University is keen to prepare a pipeline of projects for development in this area, in what is anticipated, to be an annual call. |
Year(s) Of Engagement Activity | 2019 |
Description | Will members of my family develop Alzheimers disease?' |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Public/other audiences |
Results and Impact | Dr Rebecca Sims presented "Will members of my family develop Alzheimer's disease?" at CADR Meeting Swansea, 2/8/2018. This reached an audience of 50 persons including general public, medical professionals, researchers and carers. This generated a number of questions and discussion after the talk, and was part of a wider discussion following other presentations focusing on similar topics. |
Year(s) Of Engagement Activity | 2018 |
Description | Women in Industry |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | Local |
Primary Audience | Industry/Business |
Results and Impact | Presentation to Women in Industry event, providing overview of career, advice for women in STEM careers |
Year(s) Of Engagement Activity | 2019 |
Description | Women in Science film |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Women in Science video as one of the interviewees / case studies. |
Year(s) Of Engagement Activity | 2019 |
Description | World Dementia Conference - speaker |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | This WDC summit meeting was focused on 'Looking to the Future: The Dementia landscape' and followed the series of global dialogues as part of the WDC's dementia landscape project. Discussion took place on the science and research agenda and built on previous conversations of international dementia leaders around innovation and incentives and data sharing. As a guest speaker, asking the question 'are we on track', we explored whether the research and policy landscape facilitating the development of new treatments required global co-ordination, considered whether the right things are being funded and whether new funding models were required. |
Year(s) Of Engagement Activity | 2021 |
Description | World Dementia Council |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Speaker |
Year(s) Of Engagement Activity | 2022 |