Building Genomics sequencing competency across West African partners
Lead Research Organisation:
London School of Hygiene & Tropical Medicine
Department Name: UNLISTED
Abstract
For our partners involved in molecular detection of Covid-19 without a sequencing facility, it will have
an immediate impact. SOP and lab protocol will be shared. Access will be provided to the unit HTS
and analysis using the CLIMB server and pipeline. The establishment of the genomics facilities will
contribute to the overall institutional capacity development and will involve improved staff and
stakeholder skills, knowledge and experience. Data will be uploaded into open sequence data
repositories for universal open access. Links to the data generated and the platform will accompany
all reports that will also be freely accessible online.
an immediate impact. SOP and lab protocol will be shared. Access will be provided to the unit HTS
and analysis using the CLIMB server and pipeline. The establishment of the genomics facilities will
contribute to the overall institutional capacity development and will involve improved staff and
stakeholder skills, knowledge and experience. Data will be uploaded into open sequence data
repositories for universal open access. Links to the data generated and the platform will accompany
all reports that will also be freely accessible online.
Technical Summary
Consolidate a Network of Sequencing facilities within WAGHA network
• Provide small equipment and ONT MinION sequencer, flow cells and starter pack kits for
sequencing small genomes.
• Run 2 -3 weeks face-to-face hands on training at partner institutions on sequencing workflow.
• Provide access for data analysis, training using Cloud CLIMB platform housed in the Unit.
• Provide remote support from HTC manager on training, access and analysis using established
bioinformatics pipeline.
• Provide small equipment and ONT MinION sequencer, flow cells and starter pack kits for
sequencing small genomes.
• Run 2 -3 weeks face-to-face hands on training at partner institutions on sequencing workflow.
• Provide access for data analysis, training using Cloud CLIMB platform housed in the Unit.
• Provide remote support from HTC manager on training, access and analysis using established
bioinformatics pipeline.
People |
ORCID iD |
Umberto D'Alessandro (Principal Investigator) |
Publications
Tegally H
(2022)
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance.
in Science (New York, N.Y.)
Sawadogo Y
(2022)
Genomic Epidemiology of SARS-CoV-2 in Western Burkina Faso, West Africa.
in Viruses
Onwuamah CK
(2021)
SARS-CoV-2 sequencing collaboration in west Africa shows best practices.
in The Lancet. Global health
Kanteh A
(2022)
Simple and structured model to build sequencing capacity in west Africa.
in The Lancet. Global health
Jarju S
(2022)
Circulation of respiratory viruses during the COVID-19 pandemic in The Gambia.
in Gates open research