Programme 3: Early development and risk of adult musculoskeletal disease

Lead Research Organisation: University of Southampton
Department Name: UNLISTED

Abstract

The aim of this programme is to integrate observational epidemiology and mechanistic understanding to inform novel interventions in early life to reduce the risk of later diseases such as osteoporosis and sarcopenia. Whilst our results have already informed national guidelines (DH, NICE, Public Health England and the Scientific Advisory Committee on Nutrition), the programme will advance this work by generating discovery science to delineate underlying mechanisms and to establish the wider relevance of the findings in order to inform the successful implementation of resulting public health strategies.

Technical Summary

Scientific abstract (around 400 words – max. 3,500 characters including spaces) Summary: This programme integrates observational epidemiology and mechanistic understanding to inform novel interventions in early life and thereby to reduce the risk of later diseases such as osteoporosis and sarcopenia.
Objectives: To (a) elucidate risk factors for reduced bone and muscle accrual during growth and development; (b) thus identify potential early interventions aimed at optimizing musculoskeletal development, so maximising peak bone and muscle mass, and; (c) test these
interventions, identifying mechanisms underlying, and markers of, factors which modify efficacy.
Research plan: Our future work will therefore focus on three key areas. First, study of Southampton Women’s Survey (SWS) children in late childhood/adolescence will enable us to characterise patterns of early nutrition and growth in relation to bone mass and body composition, and specifically the potential modifying effect on the pubertal transition of the earlier growth trajectory. Where potential interventions are identified and instruments are available, studies of causal inference may be undertaken using the UK Biobank cohort to inform new randomised controlled trials. We will use novel DXA image-derived phenotypes as part of our Wellcome Trust AUGMENT Award to investigate early life influences on novel indices of adult bone health in UK Biobank. With Programmes 1 and 2, this work will be complemented by novel intergenerational studies in the Hertfordshire Cohort and SWS, assessing phenotype and health across generations. Secondly, we will investigate the replication and persistence of the finding that maternal gestational vitamin D supplementation leads to improved offspring neonatal bone mass amongst winter births, using the SPRING trial (replication) and later childhood follow-up in MAVIDOS (persistence), together with adjunctive analyses in other populations, for example in novel trials such as NiPPeR and HeLTI trials in South Africa, India and China. Lastly, using experimental medicine approaches nested within our larger intervention studies, we will delineate mechanisms by which the impact of our interventions might be maximised, in a precision medicine approach, for example elucidating the influence of genetic polymorphisms on response to vitamin D supplementation and associated bone turnover, and markers of response using epigenetic profiles.
Impact: This programme will enable us to identify new public health approaches to optimise musculoskeletal development into adulthood, and characterise mechanisms underlying/modifying these early developmental influences, to ultimately reduce the burden of musculoskeletal diseases such as osteoporosis and sarcopenia in older age.

People

ORCID iD

Publications

10 25 50
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Padmapriya N (2021) 24-hour movement behaviour profiles and their transition in children aged 5.5 and 8 years - findings from a prospective cohort study in International Journal of Behavioral Nutrition and Physical Activity

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Naureen G (2021) A surrogate FRAX model for Pakistan. in Archives of osteoporosis

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Stephenson J (2021) A wake-up call for preconception health: a clinical review. in The British journal of general practice : the journal of the Royal College of General Practitioners

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Kanis JA (2023) Adjusting conventional FRAX estimates of fracture probability according to the number of prior falls in the preceding year. in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

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Kanis JA (2022) Adjusting conventional FRAX estimates of fracture probability according to the number of prior fractures. in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

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Lim DBN (2022) Advances in Diagnosis and Management of Childhood Osteoporosis. in Journal of clinical research in pediatric endocrinology

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Gavilanez EL (2022) An assessment of intervention thresholds for high fracture risk in Chile. in Archives of osteoporosis

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Wong BW (2021) Associations of Childcare Arrangements with Adiposity Measures in a Multi-Ethnic Asian Cohort: The GUSTO Study. in International journal of environmental research and public health

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Raisi-Estabragh Z (2022) Associations of cognitive performance with cardiovascular magnetic resonance phenotypes in the UK Biobank. in European heart journal. Cardiovascular Imaging

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Suaini NHA (2021) Atopic dermatitis trajectories to age 8 years in the GUSTO cohort. in Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

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Stephenson J (2021) Author response - a wake-up call for preconception health. in The British journal of general practice : the journal of the Royal College of General Practitioners

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Tint MT (2021) Brown Adipose Tissue, Adiposity, and Metabolic Profile in Preschool Children. in The Journal of clinical endocrinology and metabolism

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Ong YY (2021) Cardiometabolic Profile of Different Body Composition Phenotypes in Children. in The Journal of clinical endocrinology and metabolism

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Raisi-Estabragh Z (2022) Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank. in Heart (British Cardiac Society)

 
Description Co-authorship of Royal Osteoporosis Society APPG enquiry into FLS (NCH) 2021
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
 
Description European guidance on very high fracture risk (NCH, CC)
Geographic Reach Europe 
Policy Influence Type Membership of a guideline committee
 
Description National Osteoporosis Guideline Group Advisory Committee (NCH, CC)
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
 
Description Developmental origins of child neurodevelopment: Novel approaches to clinical risk prediction using an international metadataset.
Amount £364,324 (GBP)
Funding ID MR/V029169/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 11/2021 
End 10/2027
 
Description Does maternal gestational vitamin D supplementation influence offspring DNA methylation in childhood?
Amount £29,984 (GBP)
Funding ID SGL023\1072 
Organisation Academy of Medical Sciences (AMS) 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2020 
End 12/2021
 
Description Does pregnancy vitamin D supplementation alter trajectories of body composition and bone mineralisation from early childhood to adolescence? Follow-up of a randomised placebo-controlled trial.
Amount £187,294 (GBP)
Funding ID GN2969 
Organisation Action Medical Research 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2023 
End 06/2026
 
Description MRC National Musculoskeletal Network
Amount £150,847 (GBP)
Funding ID MC_PC_21022 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 02/2022 
End 02/2024
 
Description Nutritional determinants of skeletal development and bone loss: an investigation using a novel computer vision assessment of bone microarchitecture
Amount £36,000 (GBP)
Organisation University of Southampton 
Sector Academic/University
Country United Kingdom
Start 09/2022 
End 09/2025
 
Description Preventing broken bones in older people: from research to policy to practice
Amount £29,566 (GBP)
Funding ID MRF-145-0011-DG-HARV-C0913 
Organisation Medical Research Council (MRC) 
Department Medical Research Foundation
Sector Charity/Non Profit
Country United Kingdom
Start 03/2022 
End 09/2022
 
Title Dataset for paper :Maternal and fetal genetic variation in vitamin D metabolism and umbilical cord blood 25-hydroxyvitamin D - Supplemental Tables and Figures 
Description Supplemental tables and figures to accompany the paper "Maternal and fetal genetic variation in vitamin D metabolism and umbilical cord blood 25-hydroxyvitamin D" by RJ Moon, LDF Cooke, S D'Angelo, EM Curtis, P Titcombe, JH Davies, KM Godfrey, JK Cleal, RM Lewis, C Cooper & NC Harvey 
Type Of Material Database/Collection of data 
Year Produced 2022 
Provided To Others? Yes  
URL https://eprints.soton.ac.uk/455706/
 
Title SPRING Trial 
Description SPRING Trial 
Type Of Material Database/Collection of data 
Year Produced 2021 
Provided To Others? No  
Impact SPRING Trial 
 
Description ALPHABET 
Organisation Erasmus University Rotterdam
Country Netherlands 
Sector Academic/University 
PI Contribution Epigenetic determinants of bone development
Collaborator Contribution Epigenetic determinants of body composition and cognition
Impact N/A
Start Year 2016
 
Description ALPHABET 
Organisation National Institute of Health and Medical Research (INSERM)
Department Center for Epidemiological and Bio Statistics Research at Sorbonne
Country France 
Sector Public 
PI Contribution Epigenetic determinants of bone development
Collaborator Contribution Epigenetic determinants of body composition and cognition
Impact N/A
Start Year 2016
 
Description ALPHABET 
Organisation University College Dublin
Department School of Physics
Country Ireland 
Sector Academic/University 
PI Contribution Epigenetic determinants of bone development
Collaborator Contribution Epigenetic determinants of body composition and cognition
Impact N/A
Start Year 2016
 
Description ALPHABET 
Organisation University College Dublin
Country Ireland 
Sector Academic/University 
PI Contribution WP5, bone outcomes
Collaborator Contribution Consortium
Impact Ongoing
Start Year 2017
 
Description ALPHABET 
Organisation University of Bristol
Department Biomedical Research Unit in Nutrition, Diet and Lifestyle
Country United Kingdom 
Sector Hospitals 
PI Contribution Epigenetic determinants of bone development
Collaborator Contribution Epigenetic determinants of body composition and cognition
Impact N/A
Start Year 2016
 
Description ALPHABET 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution WP5, bone outcomes
Collaborator Contribution Consortium
Impact Ongoing
Start Year 2017
 
Description ALPHABET 
Organisation University of South Carolina
Department Arnold School of Public Health
Country United States 
Sector Academic/University 
PI Contribution Epigenetic determinants of bone development
Collaborator Contribution Epigenetic determinants of body composition and cognition
Impact N/A
Start Year 2016
 
Description AUGMENT UK Biobank collaboration 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution AUGMENT UK Biobank collaboration
Collaborator Contribution AUGMENT UK Biobank collaboration
Impact AUGMENT UK Biobank collaboration
Start Year 2017
 
Description AUGMENT UK Biobank collaboration 
Organisation University of Manchester
Country United Kingdom 
Sector Academic/University 
PI Contribution AUGMENT UK Biobank collaboration
Collaborator Contribution AUGMENT UK Biobank collaboration
Impact AUGMENT UK Biobank collaboration
Start Year 2017
 
Description Collaborative preconception research - HELMS 
Organisation KK Women and Childrens Hospital, Singapore
Country Singapore 
Sector Hospitals 
PI Contribution Collaboration to develop the study protocol for Healthy Early Life Moments in Singapore (HELMS), a single-arm pilot implementation model
Collaborator Contribution Collaboration to develop the study protocol for Healthy Early Life Moments in Singapore (HELMS), a single-arm pilot implementation model
Impact Multi-disciplinary obstetrics & public health
Start Year 2021
 
Description Collaborative research with the Singapore S-PRESTO study team 
Organisation Agency for Science, Technology and Research (A*STAR)
Department Singapore Institute for Clinical Sciences
Country Singapore 
Sector Academic/University 
PI Contribution Collaborative research within the Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO), a preconception, longitudinal cohort study that aims to study the effects of nutrition, lifestyle, and maternal mood prior to and during pregnancy on the epigenome of the offspring and clinically important outcomes including duration of gestation, fetal growth, metabolic and neural phenotypes in the offspring.
Collaborator Contribution Collaborative research within the Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO), a preconception, longitudinal cohort study that aims to study the effects of nutrition, lifestyle, and maternal mood prior to and during pregnancy on the epigenome of the offspring and clinically important outcomes including duration of gestation, fetal growth, metabolic and neural phenotypes in the offspring.
Impact Research publications
Start Year 2021
 
Description LifeLab Soweto 
Organisation University of the Witwatersrand
Department Wits Reproductive Health and HIV Institute
Country South Africa 
Sector Academic/University 
PI Contribution Collaboration to design, develop, deliver and evaluate an educational intervention in Soweto as part of a strategy to support the wellbeing of young people and their families.
Collaborator Contribution Collaboration to design, develop, deliver and evaluate an educational intervention in Soweto as part of a strategy to support the wellbeing of young people and their families.
Impact Multi-disciplinary health and education
Start Year 2021
 
Description LifeLab Soweto 
Organisation University of the Witwatersrand
Country South Africa 
Sector Academic/University 
PI Contribution Collaboration to design, develop, deliver and evaluate an educational intervention in Soweto as part of a strategy to support the wellbeing of young people and their families.
Collaborator Contribution Collaboration to design, develop, deliver and evaluate an educational intervention in Soweto as part of a strategy to support the wellbeing of young people and their families.
Impact Multi-disciplinary health and education
Start Year 2021
 
Description MAVIDOS Childhood Follow up 
Organisation University of Sheffield
Country United Kingdom 
Sector Academic/University 
PI Contribution Recruitment to MAVIDOS 6 year follow-up in Sheffield
Collaborator Contribution Recruitment to MAVIDOS six-year follow-up in Sheffield
Impact N/A
Start Year 2016
 
Description MRC National Musculoskeletal Ageing Network 
Organisation Newcastle University
Country United Kingdom 
Sector Academic/University 
PI Contribution MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres.
Collaborator Contribution Development of novel strategy to address frailty transition in older age
Impact Publish strategy paper, workshops, seminars, grant applications.
Start Year 2022
 
Description MRC National Musculoskeletal Ageing Network 
Organisation University of Birmingham
Country United Kingdom 
Sector Academic/University 
PI Contribution MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres.
Collaborator Contribution Development of novel strategy to address frailty transition in older age
Impact Publish strategy paper, workshops, seminars, grant applications.
Start Year 2022
 
Description MRC National Musculoskeletal Ageing Network 
Organisation University of Liverpool
Department School of Medicine Liverpool
Country United Kingdom 
Sector Academic/University 
PI Contribution MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres.
Collaborator Contribution Development of novel strategy to address frailty transition in older age
Impact Publish strategy paper, workshops, seminars, grant applications.
Start Year 2022
 
Description MRC National Musculoskeletal Ageing Network 
Organisation University of Nottingham
Department School of Biology Nottingham
Country United Kingdom 
Sector Academic/University 
PI Contribution MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres.
Collaborator Contribution Development of novel strategy to address frailty transition in older age
Impact Publish strategy paper, workshops, seminars, grant applications.
Start Year 2022
 
Description MRC National Musculoskeletal Ageing Network 
Organisation University of Sheffield
Department Sheffield Biorepository
Country United Kingdom 
Sector Academic/University 
PI Contribution MRC National Musculoskeletal Ageing Network, Comprising MRC Lifecourse Epidemiology Centre, MRC-Versus Arthritis Centre for Integrated research in Musculoskeletal Ageing (CIMA), MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research (CMAR), MRC Epidemiology Unit, MRC Integrative Epidemiology Unit, and MRC Unit for Lifelong Health and Ageing. Together these span the Universities of Southampton, Sheffield, Liverpool, Newcastle, Nottingham, Birmingham, Oxford, Bristol, Cambridge and UCL, with further links to associated NIHR Biomedical Research Centres.
Collaborator Contribution Development of novel strategy to address frailty transition in older age
Impact Publish strategy paper, workshops, seminars, grant applications.
Start Year 2022
 
Description Microbial derived metabolomics collaboration 
Organisation Southampton NIHR Biomedical Research Centre in Nutrition
Country United Kingdom 
Sector Public 
PI Contribution Concept to measure microbial derived metabolomics and relate these to infantile atopic dermatitis
Collaborator Contribution Mass spectrometry and metabolomics expertise
Impact Application for an Academy of Medical Sciences Starter Grant for Clinical Lecturers
Start Year 2021
 
Description UKRI (BBSRC/MRC) UK Ageing Network 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC)
Country United Kingdom 
Sector Public 
PI Contribution MyAge (Muscle resilience across the life course: from cells to society) network - member of leadership team
Collaborator Contribution MyAge (Muscle resilience across the life course: from cells to society) network
Impact Media communication at launch: https://www.southampton.ac.uk/news/2022/03/muscle-resilience-research.page
Start Year 2022
 
Description UKRI (BBSRC/MRC) UK Ageing Network 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution MyAge (Muscle resilience across the life course: from cells to society) network - member of leadership team
Collaborator Contribution MyAge (Muscle resilience across the life course: from cells to society) network
Impact Media communication at launch: https://www.southampton.ac.uk/news/2022/03/muscle-resilience-research.page
Start Year 2022
 
Description UKRI (BBSRC/MRC) UK Ageing Network 
Organisation Medical Research Council (MRC)
Country United Kingdom 
Sector Public 
PI Contribution MyAge (Muscle resilience across the life course: from cells to society) network - member of leadership team
Collaborator Contribution MyAge (Muscle resilience across the life course: from cells to society) network
Impact Media communication at launch: https://www.southampton.ac.uk/news/2022/03/muscle-resilience-research.page
Start Year 2022
 
Description UKRI (BBSRC/MRC) UK Ageing Network 
Organisation University of Birmingham
Country United Kingdom 
Sector Academic/University 
PI Contribution MyAge (Muscle resilience across the life course: from cells to society) network - member of leadership team
Collaborator Contribution MyAge (Muscle resilience across the life course: from cells to society) network
Impact Media communication at launch: https://www.southampton.ac.uk/news/2022/03/muscle-resilience-research.page
Start Year 2022
 
Description UKRI (BBSRC/MRC) UK Ageing Network 
Organisation University of Nottingham
Country United Kingdom 
Sector Academic/University 
PI Contribution MyAge (Muscle resilience across the life course: from cells to society) network - member of leadership team
Collaborator Contribution MyAge (Muscle resilience across the life course: from cells to society) network
Impact Media communication at launch: https://www.southampton.ac.uk/news/2022/03/muscle-resilience-research.page
Start Year 2022
 
Title CE Marked kit for COVID-19 saliva testing 
Description CE Marked kit for COVID-19 saliva testing 
Type Diagnostic Tool - Non-Imaging
Current Stage Of Development Market authorisation
Year Development Stage Completed 2022
Development Status Under active development/distribution
Impact Reduced community COVID transmission and increased school attendance at the height of the second COVID wave 
 
Title MAVIDOS trial vitamin D intervention 
Description Vitamin D supplementation 
Type Preventative Intervention - Nutrition and Chemoprevention
Current Stage Of Development Wide-scale adoption
Year Development Stage Completed 2021
Development Status Under active development/distribution
Clinical Trial? Yes
Impact Maternal vitamin D supplementation led to greater bone mass in the offspring for winter births 
 
Title SPRING Pregnancy vitamin D supplementation trial 
Description Trial of vitamin D supplementation during pregnancy 
Type Preventative Intervention - Nutrition and Chemoprevention
Current Stage Of Development Wide-scale adoption
Year Development Stage Completed 2021
Development Status Under active development/distribution
Clinical Trial? Yes
Impact Trial of vitamin D supplementation during pregnancy 
 
Description 114th Annual Meeting of the Association of Physicians 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this online meeting on 16th March 2021. This was a APAM online Inauguration. The meeting was hosted by University of Oxford.
Year(s) Of Engagement Activity 2021
URL https://aopgbi.org/
 
Description 8th IOF Asia Pacific Regional Conference Programme, IOF Regional Bangkok 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this conference, and gave a talk entitled 'Osteoporosis Management in 2021: South Asia meets Europe'.
This took place on 1st December 2021.
Year(s) Of Engagement Activity 2021
URL http://www.iof-regional.org
 
Description ASBMR online (EC) 2021 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation at ASBMR, USA
Year(s) Of Engagement Activity 2021
 
Description ASBMR-ECTS debate EC 2021 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact ASBMR-ECTS debate EC 2021
Year(s) Of Engagement Activity 2021
 
Description Abstract Writing Masterclass 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Nick Harvey presented the MRC National Musculoskeletal Ageing Network abstract writing seminar, which took place on December 13th 2022.
Year(s) Of Engagement Activity 2022
 
Description Academy Advisory Committee Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 21st April 2021. The meeting was attended by over 10 people.
Year(s) Of Engagement Activity 2021
URL http://www.theros.org.uk
 
Description Article written by Nick Harvey in UoS Enews 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Nick Harvey wrote an article for the University of Southampton
Enews in which he wrote about the welcome return to face-face- meetings;
the opportunity for in-person participation in the American Society for Bone
and Mineral Research Annual Scientific Conference in Austin, Texas and to
be able to catch up with colleagues and friends from all over the world. He
also mentioned that the new term brings progression of a major initiative in
UK musculoskeletal science with the consolidation of the strategic
framework for our UKRI MRC National Musculoskeletal Ageing Network.
The network will be led by the University of Southampton. He also added
that it was great to see the exciting news of the UK Biobank Repeat Imaging
Study recently made public.
Year(s) Of Engagement Activity 2022
 
Description Association for the Study of Obesity national webinar 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact "Maternal obesity and the health of the next generation", invited keynote speaker
Year(s) Of Engagement Activity 2021
 
Description BRC Science Forum Friday 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact During the current pandemic, NIHR Southampton Biomedical Research Centre hold a weekly forum to discuss the latest research. All staff with a University of Southampton login to Teams can access the recordings of these talks. Cyrus Cooper gave his talk on Lifecourse Epidemiology of Musculoskeletal Disorders on 12th January 2021.
Year(s) Of Engagement Activity 2021
URL https://web.microsoftstream.com/video/0cd14716-d313-4398-b541-52df9e72aa54?referrer=https:%2F%2Fwww....
 
Description BRC Science Forum Friday KMG 2021 - KMG 2022 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact At the BRC Science Forum Friday Professor Keith Godfrey gave a presentation from 1.30 - 2.00 p.m. This presentation was an idea for the proposed BRC Research themes for the next BRC application 2022 - 2027.
Year(s) Of Engagement Activity 2021
 
Description Blog 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Professor Cyrus Cooper discussed how and why we should preserve creativity in times of crisis on both a personal and professional level. Blog attached.
Blog was called Medically speaking.
Year(s) Of Engagement Activity 2021
 
Description COVID-19 RT-LAMP testing has high accuracy in individuals with and without symptoms 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Press release relating to multisite clinical evaluation published in the Journal of Molecular Diagnostics, which defined the clinical performance of the RT-LAMP assay for COVID-19 testing using saliva and swabs, both directly (Direct RT-LAMP) on the sample and after extraction of the viral RNA (RNA RT-LAMP). The "real world" evaluation of an improved sample preparation method for direct RT-LAMP testing for detection of COVID-19 conducted by NHS Trusts and universities demonstrated high accuracy in individuals with and without symptoms.
Year(s) Of Engagement Activity 2021
URL https://www.southampton.ac.uk/news/2022/01/lamp-testing-accuracy.page
 
Description Chair ASBMR IOF joint session at ASBMR 2021 (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Chair ASBMR IOF joint session at ASBMR 2021 (NCH)
Year(s) Of Engagement Activity 2021
 
Description EAG teleconference: Osteoporosis and Fragility Fractures Policy Network 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 16th September. The meeting was called 'ASBMR Secondary Fracture Prevention Initiative, Full Coalition Call'
Year(s) Of Engagement Activity 2021
URL https://www.osteopolicynetwork.org
 
Description ECTS 2021 Congress 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper gave a presentation entitled: 'Building Bones in Young Individuals' at the ECTS 2021 Congress.
This was attended by over 100 people.
Year(s) Of Engagement Activity 2021
URL http://www.ects2021.org
 
Description Evaluation of the expanded Southampton pilot study (Phase 2) for use of saliva-based lamp testing in asymptomatic populations KMG 2021 - KMG 2022 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact The University News wrote about the report published on the evaluation of the expanded Southampton pilot study (Phase 2) for use of saliva-based lamp testing in asymptomatic populations. Final report 16th November 2020. The lead author of this report was Professor Keith Godfrey, Professor Janis Baird and Professor Mary Barker were also authors. The title of the article was "Southampton pilot demonstrates effective COVID-19 testing in school and University settings.
Year(s) Of Engagement Activity 2021
URL https://doi.org/10.5258/SOTON/P0045
 
Description FRAX Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attending a FRAX meeting, held by University of Sheffield on 4th March 2021
Year(s) Of Engagement Activity 2021
 
Description Fellowship Committee Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus attended this meeting on 10th May 2021.
There were over 100 people in attendance.
Year(s) Of Engagement Activity 2021
URL http://www.acmedsci.ac.uk
 
Description Gestational vitamin D supplementation: observation mechanism and intervention in the MAVIDOS trial. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Nick Harvey gave a talk at the BSR Science Forum on 18th February 2022. Up to 50 people attended.
Year(s) Of Engagement Activity 2022
 
Description International Venice Forum: Why investing in Maternal, Newborn and Child Health (MNCH) is critical for sustainable recovery after COVID-19 - KMG 2022 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Keith Godfrey gave a presentation during Theme E entitled "Test, Trace and Learn - Lessons from the COVID 19 pandemic that will guide further public health preparedness and inform health policy research going forward. there were over 100 paticipants from 40 countries taking part in this International Venice Forum: Why investing in Maternal, Newborn and Child Health (MNCH) is critical for sustainable recovery after COVID-19
Year(s) Of Engagement Activity 2021
URL https://www.fisv.org/wp-content/uploads/2021/03/Draft-Programme-Venice-MNCH-Forum.pdf
 
Description Interview Rosemary Lobley of HEQ 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper gave an interview to Rosemary Lobley of HEQ about Osteoporosis, diagnosis, prevention, and treatment. The article is from issue 16 of Health Europa.
The date of the interview was 17th February 2021.
Year(s) Of Engagement Activity 2021
URL https://www.healtheuropa.eu/osteoporosis-diagnosis-prevention-and-treatment/105953/
 
Description Invited Chair joint IOF SIBOMM session (NCH) 2021 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited Chair joint IOF SIBOMM session (NCH) 2021
Year(s) Of Engagement Activity 2021
 
Description Invited presentation BRADOO 2021 (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited presentation BRADOO 2021 (NCH)
Year(s) Of Engagement Activity 2021
 
Description Invited presentation at Belgian Bone Club 2022 (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited presentation at Belgian Bone Club 2022 (NCH)
Year(s) Of Engagement Activity 2022
 
Description Invited presentation at SICOT (NCH) 21 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited presentation at SICOT (NCH) 21
Year(s) Of Engagement Activity 2021
 
Description Lay presentation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Nick Harvey delivered a lay presentation on Osteoporosis to the Patient Partner Group at the St Francis Surgery in Hedge End, Southampton. Around 100 people attended.
Year(s) Of Engagement Activity 2023
 
Description Lecture at BRS Conference Oxford 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper gave a lecture entitled 'Fracture Epidemiology Across the Globe'.
This took place on 28th June 2021. Over 100 people attended.
Year(s) Of Engagement Activity 2021
URL http://www.boneresearchsociety.org
 
Description LifeLab Online 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Development of online scientific literacy & engagement resources, including relating to COVID-19 testing and transmission
Year(s) Of Engagement Activity 2021
 
Description Lister Prize Interviews 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attending this event on 19th May 2021.
Year(s) Of Engagement Activity 2021
 
Description MTP WCO (EC) 2021 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Meet The Expert session at World Congress and Osteoporosis
Year(s) Of Engagement Activity 2021
 
Description MTP WCO 2021 (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Meet The Professor session at World Congress in Osteoporosis 2021
Year(s) Of Engagement Activity 2021
 
Description Media attention for published paper Br J Dermatology 2022;187:659-66 - KMG 2023 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact El Heis S, D'Angelo S, Curtis EM, Healy E, Moon RJ, Crozier SR, Inskip H, Cooper C, Harvey NC, Godfrey KM and the MAVIDOS Trial Group. Maternal antenatal vitamin D supplementation and offspring risk of atopic eczema in the first 4 years of life: evidence from a randomized controlled trial. British Journal of Dermatology. 2022;187:659-666.

This paper received a lot of media attention from numerous outlets, including 29 websites and 54 social media platforms. It was in the top 5% of all research outputs scored by Almetric. Articles included a write up in the magazine Mother.ly, The University of Southampton News page and numerous others details of which are attached.
Year(s) Of Engagement Activity 2022
 
Description NIH Strategic Workshop, Preconceptional Origins of Child Health Outcomes 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact "Preconception nutrition to optimise offspring life chances", Invited Keynote Speaker
Year(s) Of Engagement Activity 2021
 
Description Nutrition Society Summer Meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited keynote speaker "Maternal preconception nutrition and the life chances of the next generation"
Year(s) Of Engagement Activity 2021
 
Description Pagets Information Day 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper gave the Introduction speech at the Pagets Information day on 8th October 2021.
Year(s) Of Engagement Activity 2021
 
Description Presentation at 3rd World Congress on Maternal Neonatal Medicine - KMG 2022 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Keith Godfrey gave a presentation entitled Periconceptional stressors at the 3rd World Congress on Maternal Neonatal Medicine. There were 1640 participants from 88 countries at this event.
Year(s) Of Engagement Activity 2021
URL https://www.mcascientificevents.eu/worldmfnm/
 
Description Presentation at BSR (EC) 2021 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation at British Society for Rheumatology
Year(s) Of Engagement Activity 2021
 
Description Presentation at WCO 2021 (NCH) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation at World Congress in Osteoporosis 2021
Year(s) Of Engagement Activity 2021
 
Description Presentations at WCO (EC) 2021 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presentation at World Congress in osteoporosis
Year(s) Of Engagement Activity 2021
 
Description Press Release and Publicity - findings from the NIPPER study - SB & KMG 2021 - KMG 2022 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact This publication (Godfrey K, Barton SJ, El-Heis S, Kenealy T, Nield H, Baker PN, Chon YS, Cutfield W, Chan S-Y, Nipper Study Group. Myo-Inositol,probioticsand microntrient supplementation from preconception for glycemia in pregnancy: NiPPeR International Multicenter Double-Blind Ramdomised Controlled Trial. Diabetes Care published online 29 March 2021 doi;.org/10.2337/dc20-2515.) of the findings from the NiPPeR study in this paper received some publicity from both Nestle and Food in Progress as well as being reported by the University of Southampton. The findings show that a mother's diet before and during pregnancy is important for herself and gives her baby the best start in life. The supplementation given to the women taking part in the NiPPeR study was linked to reduced risk of pre-term birth. The publication can be found at: https://www.foodinprogress.com/study-links-nutritional-supplementation-taken-preconception-and-in-pregnancy-to-a-reduced-risk-of-preterm-birth/;
Year(s) Of Engagement Activity 2021
URL https://www.southampton.ac.uk/news/2021/03/nipper-trial-reduced-preterm-birth.page
 
Description Press Release and publication of paper 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Press release for the paper entitled "Is the skull responsive to bone mineralisation stimuli in children? published in the journal Bone.
There was some media attention following the publication of this paper. The press release was entitled "Skulls stay strong despite worse diets"
Year(s) Of Engagement Activity 2022
 
Description Press Release of published paper 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact There were a number of online citings following a press release entitled "Three coffees a day could help keep the doctor away."
This was to do with an article published in European Journal of Preventive Cardiology entitled:
Light to moderated coffee consumption is associated with lower risk of death: UK Biobank Study.
Simon J, Fung K, et al.
Year(s) Of Engagement Activity 2022
 
Description Press release for published paper 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact A press release came out on 12th August 2022 for the paper entitled "Menopausal hormone therapy reduces the risk of fracture regardless of falls risk or baseline FRAX probability - results from the Women's Health Initiative hormone therapy trials." The paper was published in Osteoporosis International.
Year(s) Of Engagement Activity 2022
 
Description Preventing broken bones in older people: from research to policy to practice 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact The University Faculty of Medicine print a Research Roundup Newsletter. These newsletters aim to celebrate success, provide research updates and give information on upcoming opportunities. The second of these newsletters was written by Professor Nick Harvey.
Year(s) Of Engagement Activity 2022
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 28th January 2021, as an Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 28th April 2021, as an Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 13th May 2021, as an Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 16th July 2021.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 19th May 2021, as an Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 19th November 2021, as an Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 19th April 2021, as an Impact Assessor
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 21st October 2021, as an Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 31st August 2021, as a Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 18th & 19th August 2021, as an Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 21st October 2021, as an Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attending a REF meeting on 17th March 2021, as an Impact Assesor
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 18th June 2021.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 21st September 2021, as an Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on May 4th 2021, as an Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 1st September 2021, as an Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description REF Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 23rd December 2021, as an Impact Assessor.
Year(s) Of Engagement Activity 2021
 
Description Royal Osteoporosis Society public event 2021 (NCH) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Working group vitamin D ESCEO 21 (NCH)
Year(s) Of Engagement Activity 2021
 
Description Speaker at ArLAR Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper was a speaker at the ArLAR Conference.
He gave a talk entitled 'Nutritional Approach of Osteoporosis and Fracture Prevention'. This took place on 5th March 2021
Year(s) Of Engagement Activity 2021
URL https://www.arabrheumatology.org
 
Description Speaker at BRADOO - ABRASSO Congress (Brazilian Association of Bone Assessment and Osteometabolism. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper gave a talk at this conference entitled 'Closing the treatment gap: An urgent Priority is Osteoporosis Care Worldwide'.
This took place on 24th April 2021.
Year(s) Of Engagement Activity 2021
 
Description Speaker at Polish Osteoarthrology Society 8th Central European Congress on Osteoporosis and Osteoarthritis. 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attending this congress meeting, and gave a talk entitled 'Management of patients with low, high, and very high risk of osteoporotic fractures'. The meeting was held on 22nd October 2021.
Year(s) Of Engagement Activity 2021
 
Description Speaker at WCO-IOF ESCEO Congress (virtual). 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper was a Speaker at this online conference.
His talk was entitled 'Management of musculoskeletal disease from cradle to grave.'
This took place between 26-27th August 2021, and was attended by over 100 people.
Year(s) Of Engagement Activity 2021
URL https://virtual.wco-iof-esceo.org
 
Description Speaker at e-ECE2021 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper gave a talk entitled '1 year in Bone'. The event took place on 24th May 2021.
Year(s) Of Engagement Activity 2021
 
Description Starter Grants for Clinical Lecturers Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 3rd June 2021.
Year(s) Of Engagement Activity 2021
 
Description The 11th ICFSR Conference ASBMR 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this conference on 1st October 2021, and gave a talk entitled 'IOF Capture the Fracture Partnership'.
Year(s) Of Engagement Activity 2021
 
Description UKHSA/NHS-England COVID Testing Roadshow 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation "Overview of LAMP technology development and asymptomatic NHS staff testing for COVID-19"
Year(s) Of Engagement Activity 2021
 
Description UKRI National Ageing Research network 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Announcement that the University of Southampton will lead one of the eleven new national research networks to tackle challenges in ageing, announced today by the Biotechnology and Biological Sciences Research Council (BBSRC) and Medical Research Council (MRC). Keith Godfrey part of a team of scientists at the University who will lead the MyAge (Muscle resilience across the life course: from cells to society) network. Over the course of the two year project, they aim to build new collaborations and hypotheses for the future of research in this area and develop a roadmap to interventions that can achieve five more years of independent living.
Year(s) Of Engagement Activity 2021
URL https://www.southampton.ac.uk/news/2022/03/muscle-resilience-research.page
 
Description University of Southampton Science and Engineering Day 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Nick Harvey was part of a team from the MRC LEU that took part in this event. The event was well attended with members of the public showing great interest.
Year(s) Of Engagement Activity 2022
 
Description Versus Arthritis RISAPS Supplement Review Meeting 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Cyrus Cooper attended this meeting on 7th May 2021.
Year(s) Of Engagement Activity 2021
URL https://versusarthritis.org
 
Description WCO-IOF-ESCEO Conference - Virtual 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Professor Nick Harvey, Deputy Director of MRC LEU gave the Plenary Lecture 2 entitled 'Update of the management of patients at imminent fracture risk at the WCO-IOF-ESCEO conference on 24th March 2022, which was held virtually. This was attended by over 1,000 people.
Year(s) Of Engagement Activity 2022
 
Description Working group on phosphate disorders ES CEO 2021 (NCH) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Working group vitamin D ESCEO 21 (NCH)
Year(s) Of Engagement Activity 2021
 
Description Working group vitamin D ESCEO 21 (NCH) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Working group vitamin D ESCEO 21 (NCH)
Year(s) Of Engagement Activity 2021