Viral Hepatitis

Lead Research Organisation: University of Glasgow

Abstract

HCV vaccine
Dr John McLauchlan and Dr Arvind Patel, Lead Investigators, and Dr Emma Thomson as a Co-Investigator, MRC-University of Glasgow Centre for Virus Research (CVR), University of Glasgow.
Hepatitis C virus (HCV) is passed on through blood-to-blood contact and infects the liver. In most cases, after initial infection, it remains in the blood and the liver unless those who are infected receive treatment to clear the virus. Over a long period, up to 10-20 years after infection, liver disease can develop which may lead to liver failure or cancer. Since infection is not always obvious, people are frequently unaware that they carry the virus. As a result, HCV infection is a global clinical problem; in the UK, there are up to 215,000 infected people but only about half of them have been diagnosed.
Our programme aims to understand how HCV changes in people who are infected. This is important because some people can develop resistance to the drugs used to treat the virus. Currently, there are new but expensive drugs available to cure infection. However, not everyone responds because they become resistant. We are trying to understand what changes occur in the virus to make people resistant and why these changes happen. In addition, we believe that eradicating HCV needs a vaccine, especially for poor countries that cannot afford drugs. Therefore, we are also looking at the antibodies which are naturally produced during infection to make a vaccine that would protect people from the virus.

Technical Summary

HCV will remain a serious healthcare burden for the foreseeable future and despite attempts at intervention, new infections will persist, particularly in the 'people who inject drugs' (PWID) group. Emergence of antiviral resistance that could be transmitted in the community, and the impact of the inherent diversity within and between HCV genotypes on patient treatment are crucial challenges. In addition, virus evolution occurs in a genetically diverse host background, ultimately shaping response to infection. Fundamental questions on the contribution of host factors to pathogenesis and their role in determining the outcome of DAA therapy need to be addressed for those who fail to clear virus. Our core objective is to tackle viral evolution and host response as interconnected issues. We have developed initiatives and expertise which are central to our plans. To translate our research findings for clinical benefit, we will capitalize on HCV Research UK as a unique resource for clinical data and samples and utilize next generation sequencing (NGS) and bioinformatics pipelines to determine the evolution of viral resistance in those who do not respond to therapy. In addition, creation of gene knockouts by CRISPR technology combined with single cell sequencing will be pivotal for understanding the contribution of host factors as drivers of viral diversity, including DAA-resistance. Our future programme thus encompasses clinical to fundamental research, populations to single cells, incorporating in vivo, in vitro and in silico dimensions.
In the same vein, we set out a strategic plan for the rational design of a HCV vaccine from our studies on neutralising antibodies. Virus eradication will not succeed through antiviral therapy alone due to lack of availability and cost, and resistance may be problematic. Our aim is to isolate unique antibodies from niche patient cohorts from HCV Research UK that are otherwise difficult to access. Again, our objectives are rooted in extensive expertise allied to the benefits of core-funded sequencing platforms and cognate bioinformatics expertise. Moreover, the collaborative network established with a range of disciplines will energise the plans and bring unique ideas to confront the obstacles preventing vaccine development.

Publications

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Abdelrahman T (2015) Reply: To PMID 24797101. in Hepatology (Baltimore, Md.)

 
Guideline Title EASL Recommendations on Treatment of Hepatitis C 2016
Description HCV Research UK - EASL Guidelines
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in clinical guidelines
 
Description PHE Working Group on HCV Anti-Viral Resistance
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
URL https://www.gov.uk/government/publications/antiviral-resistance-testing-in-the-management-of-hepatit...
 
Description MRC Stratified Medicine - STOP HCV
Amount £280,852 (GBP)
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 09/2013 
End 08/2018
 
Description Studies on Liver Disease
Amount £1,924,918 (GBP)
Funding ID C0365 
Organisation Medical Research Council (MRC) 
Department Medical Research Foundation
Sector Charity/Non Profit
Country United Kingdom
Start 01/2011 
End 03/2019
 
Description UK-Indonesian Consortium to Identify Biomarkers Predictive of Dengue Disease Severity.
Amount £404,258 (GBP)
Funding ID MR/P017509/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 11/2017 
End 11/2019
 
Description UK-Philippines: Joint Health Research Call
Amount £395,861 (GBP)
Funding ID MR/N019245/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 01/2016 
End 01/2019
 
Title Cell lines -ISG15 knockout cells 
Description The cell lines were created by CRISPR-Cas9 knockout of the ISG15 gene. This allows studies on the role of ISGylation, a post-translational event that has critical roles in regulating cellular pathways and processes. 
Type Of Material Cell line 
Year Produced 2016 
Provided To Others? Yes  
Impact Preliminary data has shown that the cells have a distinct phenotype during virus infection. This line of research is being continued by our collaborators. 
 
Title HCV Research UK Research Database 
Description HCV Research UK has established both clinical and biobank databases to hold clinical data and information on biological samples from HCV-infected patients in a cohort of 12,000 individuals. The long term aim has been to integrate these data with research data from the provision of samples for research studies. This 'research database' has now been constructed and data is being entered automatically. There is also an overarching search tool across many options to identify groups with particular characteristics. 
Type Of Material Improvements to research infrastructure 
Year Produced 2018 
Provided To Others? No  
Impact None at the moment until all data entry has been completed. 
 
Title NGS Target Enrichment 
Description The technology enabled the enrichment of HCV-specific sequences in Next Generation Sequencing. It also increased the numbers of samples that could be included in a single sequencing run from about 10-12 to 90, which is much more cost effective. 
Type Of Material Technology assay or reagent 
Provided To Others? No  
Impact The methodology is now being developed for diagnostic services and to establish an enrichment platform for flaviviruses circulating in the Philippines. 
 
Title HCV Research UK Research Database 
Description HCV Research UK has established both clinical and biobank databases to hold clinical data and information on biological samples from HCV-infected patients in a cohort of 12,000 individuals. The long term aim has been to integrate these data with research data from the provision of samples for research studies. This 'research database' has now been constructed and data is being entered automatically. There is also an overarching search tool across many options to identify groups with particular characteristics. 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact None as yet as data entry is not complete. 
 
Description Contribution of compensatory variants in the HCV polyprotein that facilitate DAA resistance 
Organisation University of Copenhagen
Country Denmark 
Sector Academic/University 
PI Contribution My team has provided the viral sequence data to the collaboration through assembling HCV sequences from >100 infected patients stratified by their response to DAA therapy and HCV subtype.
Collaborator Contribution The partners have established an in vitro system for examining the drug resistance profiles of infectious HCV in tissue culture cell lines.
Impact No outputs thusfar.
Start Year 2019
 
Description Determining resistance to all-oral DAAs using in vitro systems 
Organisation Royal London Hospital
Country United Kingdom 
Sector Hospitals 
PI Contribution My group has provided HCV sequence data to direct the in vitro studies at the Royal London.
Collaborator Contribution The Royal London has carried out the in vitro studies in the project.
Impact The collaboration has given rise to oral and poster presentations at national and international conferences.
Start Year 2015
 
Description IBCP 
Organisation Institute of Biology and Chemistry of Proteins (IBCP)
Country France 
Sector Academic/University 
PI Contribution My team performs all analysis of mutant signal peptides to design suitable synthetic peptides that may be substrates for signal peptide peptidase. We test these mutant signal peptides in various systems to establish their ability to be cleaved by the enzyme
Collaborator Contribution IBCP is an institute that carries out NMR studies on proteins. Through a longstanding collaboration with the group, we have determined the structure of the HCV signal peptide that is a substrate for signal peptide peptidase. This would represent the first example of a structure for a substrate for this protease. The group at IBCP also have a protein synthesis facility that has prepared a synthetic substrate for SPP
Impact This interaction gave rise to a publication (Oehler et al in the publication list).
 
Description ISG15 cell line collaboration 
Organisation University of St Andrews
Department School of Biology
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of knockout cell lines for studies on ISG15
Collaborator Contribution Use of the cell lines to study virus infection in ISG15 knockout cell lines.
Impact No outputs as yet.
Start Year 2016
 
Description PHE - Validation assays for HCV sequencing 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution Provision of clinical and viral sequence data as well as samples for the clinical validation of a national whole genome sequencing assay for HCV.
Collaborator Contribution PHE have developed the methodology for whole genome sequencing of HCV and the data and samples were provided to validate the data they obtain from their assays.
Impact The collaboration is part of the PHE initiative to provide a service for HCV genomic diagnostics, particularly for situations in which anti-viral therapies do not cure HCV infection. The collaboration includes a Working Group on HCV Resistance; the CVR has two senior staff on the group (E Thomson and J McLauchlan)
Start Year 2018
 
Description STOP-HCV 
Organisation STOP-HCV
Country United Kingdom 
Sector Public 
PI Contribution Provision of data and samples from HCV Research UK to STOP-HCV; sharing of know-how and data in viral sequeincing and host genotyping.
Collaborator Contribution Sharing of know-how and data on viral sequencing and host genotyping.
Impact Integrated studies on viral and host genetics.
Start Year 2013
 
Description Structural studies on the IFNL4 protein 
Organisation Aarhus University
Country Denmark 
Sector Academic/University 
PI Contribution We have provided data on the antiviral activities of natural variants of the human IFNL4 protein (both partners).
Collaborator Contribution The team at Stanford has modelled predictive structures of IFNL4 and natural variants based on their previous publications on other IFNL proteins. The group in Aarhus has created constructs aimed at producing authentically folded IFNL4 proteins for structural studies.
Impact A manuscript describing the findings of the collaboration will be submitted imminently and a pre-publication version of the paper has been published in Bioarchive.
Start Year 2016
 
Description Structural studies on the IFNL4 protein 
Organisation Howard Hughes Medical Institute
Country United States 
Sector Charity/Non Profit 
PI Contribution We have provided data on the antiviral activities of natural variants of the human IFNL4 protein (both partners).
Collaborator Contribution The team at Stanford has modelled predictive structures of IFNL4 and natural variants based on their previous publications on other IFNL proteins. The group in Aarhus has created constructs aimed at producing authentically folded IFNL4 proteins for structural studies.
Impact A manuscript describing the findings of the collaboration will be submitted imminently and a pre-publication version of the paper has been published in Bioarchive.
Start Year 2016
 
Description Studies on the evolution of IFNL4 
Organisation University of Pennsylvania
Country United States 
Sector Academic/University 
PI Contribution We have provided details of novel variants in the IFNL4 gene that are both rare in humans (<1% frequency) and only found in Africa.
Collaborator Contribution Our collaborator in Pennsylvania is a leading expert on human evolution in Africa and has provided sequence data to us to identify tribes in Africa with novel IFNL4 variants.
Impact A manuscript describing our findings will be submitted imminently and the pre-publication has been published in Bioarchive.
Start Year 2017
 
Description University of Basel 
Organisation University of Basel
Department Department of Biomedicine
Country Switzerland 
Sector Academic/University 
PI Contribution My team is making use of liver biopsies to study single cell transcriptomics by laser microdissection.
Collaborator Contribution Our partners have provided unique frozen, unfixed biopsies for our single cell transcriptomic studies. They have also provided clinical and molecular data related to the biopsies that is critical for interpreting our data.
Impact None as yet.
Start Year 2015
 
Title HCV Research UK Research Database 
Description A Research Database has been constructed that links to the pre-existing HCV Research UK Clincal and Biobank Databases. This will facilitate the scope of research studies possible using HCV Research UK data and samples and enrich the data that can be made available to the research community. 
Type Of Technology Webtool/Application 
Year Produced 2019 
Open Source License? Yes  
Impact No impact as yet. 
 
Title HCV-GLUE 
Description A GLUE-based resource focused on Hepatitis C virus is HCV-GLUE. 
Type Of Technology Software 
Year Produced 2017 
Open Source License? Yes  
Impact N/A 
 
Title Target Enrichment for HCV Genomics 
Description This methodology improved the multiplexing and depth of coverage of HCV viral sequences compared to a more fundamental approach using metagenomics. The technology was developed to allow capture of viral sequences to very low levels (only a few hundred copies of viral genomes/ml). 
Type Of Technology New/Improved Technique/Technology 
Year Produced 2016 
Impact The approach is now being introduced to Public Health England for their diagnostic service to detect and identify HCV sequences. 
 
Description 24th Annual Glasgow Virology Workshop June 2019 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The CVR hosted the 24th Glasgow Virology Workshop (GVW) on Friday VV June 2019 (Sir Charles Wilson Building, University of Glasgow). This annual one-day meeting aims to communicate the latest innovative science in the world of virology, and to promote interactions between scientists and a variety of stakeholders throughout the world. This meeting is an informal and welcoming one day event comprising a mix of presentations from both external and internal speakers, along with networking sessions. It is rounded off by an evening ceilidh to provide attendees with a more relaxed opportunity to engage with one another. The annual event attracts a wide age range of attendees (from undergraduate students through to healthcare professionals, members of the biotech industry to retired professors), providing an ideal opportunity to catch up with former colleagues, establish new collaborations, and listen to truly inspirational science.
Year(s) Of Engagement Activity 2019
URL https://www.facebook.com/centreforvirusresearch/
 
Description Abbvie Medical Team 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Organised an afternoon of speakers and presentations on a) HCV diagnostics now an din the future, b) sequencing methods for identifying resistance in patients who fail therapy and c) possible issues for difficult-to-treat patients with new therapies.
Year(s) Of Engagement Activity 2014,2017
 
Description Annual PCR Workshops September 2019 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Each year the CVR runs a series of 6 individual workshops for Higher Biology school pupils. Around 100 pupils attend each workshop and travel from schools throughout Scotland. The workshops are fully booked each year and run in collaboration with the Glasgow Science Centre and supported by Thermo Fisher. The workshops require the support of around 15-20 volunteers from the CVR and wider MVLS each year. The workshops provide pupils with experience and knowledge they would not normally receive until attending university.
Year(s) Of Engagement Activity 2019
URL https://www.facebook.com/centreforvirusresearch/
 
Description April 2016 - Prof John McLauchlan - Presentation to HCV Forum 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Patients, carers and/or patient groups
Results and Impact In April 2016 Prof McLauchlan was invited to give a presentation to the HCV Forum. He presented data on possible impact of resistance to new therapies for HCV infection in Scotland. This activity formed an important form of engagement with two of our key target audiences - NHS professionals and patient groups.
Year(s) Of Engagement Activity 2016
 
Description April 2016 - Prof John McLauchlan guest Lecture Sun Yat-Sen University, Guangzhou, China 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Prof John McLauchlan was asked to present a lecture at the Sun Yat-Sen University, Guangzhou, China as part of an effort to promote collaboration between CVR and Sun Yat-Sen University. the activity promoted networking and discussion along with follow up plans.
Year(s) Of Engagement Activity 2016
 
Description April 2017 - Connor Bamford Eden Project Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact In April, CVR postdoc Connor Bamford travelled to the Eden Project in Cornwall to participate in a cross-disciplinary workshop set up to think about new ways of engaging with people about how viruses move between different species. The day-long event was held at FoAM Kernow - a not-for-profit organisation "inhabiting the spaces between society, research, education and policy" - and was really in aid of a new endeavour led by Dr Ben Longdon (a Wellcome Trust Sir Henry Dale Fellow and Royal Society Research Fellow) who has begun to establish his lab at the University of Exeter Penryn campus on the peninsula. The whole idea of the workshop was to guide the development of a game (entitled: Viruscraft - explore its new website here) based on 'tangible interfaces' - linking the digital world with real-life movements - that would help players explore the concept of cross-species transmission of viruses. The entire project is supported by the Wellcome Trust via Ben's fellowship grant. Connor found this to be a positive development opportunity and is currently leading a project to apply for an intern/exhibition slot at the Eden project during the summer of 2018. He shared his experience in a blog post - https://cvrblog.myportfolio.com/viruscraft-tangible-interfaces-in-cornwall, which was also shared on our social media channels reaching over 500 followers.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch
 
Description August 2016 - Prof John McLauchlan Lecture at The Medical City, Manila, The Philippines 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact In August 2016, Prof McLauchlan visited the Philippines to deliver a lecture to his peers at The Medical City, Manila, The Philippines. The aim of the activity was to promote collaboration between CVR and University of Manila.
Year(s) Of Engagement Activity 2016
 
Description August 2017 - Connor Bamford - Kate Bishop interview Blog post 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Following an interview with Kate Bishop in August 2018, we published a blog post to highlight key discussion points and interview questions - http://cvr.academicblogs.co.uk/switching-off-an-hiv-infection-with-samhd1/. The post has reached 681 followers on Facebook alone including likes and 4 shares by other accounts, along with 142 blog views.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch/
 
Description August 2017 - Connor Bamford and Jack Hirst - Charles Masembe interview - Blog and Podcast 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact In August 2017 CVR postdoc Connor Bamford and PhD student Jack Hirst interviewed CVR Fellow Charles Masembe to share his Uganda-based research, which focuses on African Swine Fever Virus. The podcast had 135 listens on SoundCloud and 43 views for the blog on Wordpress. The post was shared on Facebook and Twitter reaching 384 followers on Facebook alone.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch/
 
Description August 2018 - Connor Bamford Contagious Thinking Blog post 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact CVR postdoc Connor Bamford published a post to provide information about the Contagious Thinking blog and podcast. the post was shared on Facebook and Twitter and intended to recruit new followers - https://cvrblog.myportfolio.com/podcast-season-1
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch/
 
Description BBC News Story - HCV Alert Carol Leitch 23 February 2016 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Carol Leitch, at the request of Health Protection Scotland carried out the phylogenetic analysis of the 2 patient samples suspected of being infected by a healthcare worker in Lanarkshire. She was able to show that the HCV infecting these individuals was closely related and this was backed up by individuals from PHE who performed another analysis. This led to the realisation that these patients had likely been infected during a procedure carried out by the healthcare worker. This information formed the basis of a report submitted by NHS Lanarkshire to the UK Advisory Panel for Healthcare Workers Infected with Blood Borne Viruses and the national body endorsed the health board's proposal to carry out a patient notification exercise. 8383 patients treated by this healthcare worked will now be contacted and offered screening for HCV. As a result, the BBC featured a news story about the security alert- http://www.bbc.co.uk/news/uk-scotland-glasgow-west-35639826. This is an example how the work of the CVR has a direct influence on Policy, Practice, along with patients and public interests.
Year(s) Of Engagement Activity 2016
URL https://www.facebook.com/centreforvirusresearch/
 
Description BBC Scotland - Report on introduction of HCV into Scotland 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Media interview with BBC Scotland and release of information on BBC website.
Year(s) Of Engagement Activity 2015
URL http://www.bbc.co.uk/news/uk-scotland-34658098
 
Description Blog Post #4: Measles (Connor Bamford) - March 2015 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact This post received 179 views along with online comments and discussion, and likes and tweets on social media.

Connor Bamford, the author of the post, received 4 emails providing positive feedback both from other CVR researchers but also from external colleagues, demonstrating that the blog was gaining further interest and was viewed in a positive light.
Year(s) Of Engagement Activity 2015
URL https://www.facebook.com/centreforvirusresearch/
 
Description Blog for MRC Insight - 2013 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Blog written for MRC Insight to describe the aims of HCV Research UK.
Year(s) Of Engagement Activity 2013
URL http://www.insight.mrc.ac.uk/2013/01/21/a-helping-hand-for-hepatitis-c-treatment/
 
Description CVR Blog #10 Viral Hepatitis - Connor Bamford July 2015 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Our 10th blog post about Hepatitis C infection. The blog post reached 776 people on Facebook and received 563 views.
Year(s) Of Engagement Activity 2015
URL https://www.facebook.com/centreforvirusresearch/
 
Description CVR Blog #12 CVR at the Glasgow Science Festival - July 2015 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Our 12th blog showcased the CVR's activities at the Glasgow Science Festival in June 2015. The post reached 792 people on Facebook and received 183 views.
Year(s) Of Engagement Activity 2015
URL https://www.facebook.com/centreforvirusresearch/
 
Description CVR Blog #17 ADAP2 Inhibition Connor Bamford October 2015 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Our 17th Blog post by Connor Bamford on the topic of ADAP2 inhibition and virus entry into cells. The post was viewed 144 times.
Year(s) Of Engagement Activity 2015
URL https://www.facebook.com/centreforvirusresearch/
 
Description CVR Blog #7 Microtalks - Connor Bamford May 2015 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Our 7th Blog post promoting a CVR Glasgow Science Festival event. Reached 131 people on Facebook and received 160 views.
Year(s) Of Engagement Activity 2015
URL https://www.facebook.com/centreforvirusresearch/
 
Description CVR Blog Post 2: Meet the Expert Dr John Mclachlan (Veronica Rezelj) - February 2015 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact 192 people read the blog post with likes reported on Facebook and Twitter.

The increased number of views versus the first post demonstrated a heightened awareness of the blog and therefore, demonstrated an uplift in followers.
Year(s) Of Engagement Activity 2015
URL https://www.facebook.com/centreforvirusresearch/
 
Description CVR Blog post 1: Hepatitis C Virus (Connor Bamford) - February 2015 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other academic audiences (collaborators, peers etc.)
Results and Impact The blog post encouraged online comments and discussion among readers.

The post encouraged readers to follow the CVR blog therefore encouraging further future interaction and engagement.
Year(s) Of Engagement Activity 2015
URL https://www.facebook.com/centreforvirusresearch/
 
Description CVR Coffee Mornings 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Other audiences
Results and Impact We have been holding monthly coffee mornings for staff and students within our social space since 2017 to offer an informal opportunity for people working across the centre to meet and network. The events are regularly attended by 50-70 people each time with attendance continuing to grow. Staff and students have provided positive feedback about this opportunity to meet with one another and make use of it as a chance to discuss work related matters or simply to make new connections.
Year(s) Of Engagement Activity 2019
URL https://www.facebook.com/centreforvirusresearch/
 
Description CVR Contagious Thinking Podcast - Douglas Stewart naming viruses to geographical locations 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Contagious thinking podcast around how viruses get their names and the problems encountered
Year(s) Of Engagement Activity 2020
URL http://cvrblog.myportfolio.com
 
Description CVR Stoker Award 2019 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Every year, CVR early career scientists nominate and vote for an established, outstanding virologist who has made a significant contribution to their field. In 2019 CVR early career researchers presented the award to Professor Ann Palmenberg - plus podcast
Year(s) Of Engagement Activity 2019
 
Description CVR Travel Award 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact One PhD student and one post-doc are each awarded a prize of £1500 to use towards presenting at a conference of their choosing in 2020.
The Students and Postdocs are asked to submit an abstract up to 400 words in length (excluding title, authors etc) detailing the work they wish to present at the conference.
Year(s) Of Engagement Activity 2020
 
Description Carol Monaghan MP visit - 30 October 2015 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Policymakers/politicians
Results and Impact Local MP of the Glasgow North West Constituency Carol Monaghan came to visit the CVR to meet with our Director Massimo Palmarini to learn about the important research carried out at the centre along with taking in a tour of the facility. Carol was able to meet with several of our researchers who provided short presentations about their research. Carol was very enthusiastic to learn about our research, links with industry and also about importance of funding. She then went on to mention the CVR and what she had learned during the visit at a parliamentary meeting in Westminster later that week. Furthermore, she then went on to visit one of the other Biomedical research centres that forms part of the University of Glasgow to gain a further insight into some of the important work and research being carried out across the University.
Year(s) Of Engagement Activity 2015
URL https://www.facebook.com/centreforvirusresearch/
 
Description Clinical Staff - Invited Lecture on HCV Treatment 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Presented lecture on targets for new therapies for HCV infection and issues over drug resistance to clinicians and nursing staff. Feedback indicated that this improved knowledge of new treatments.
Year(s) Of Engagement Activity 2016
 
Description Connor Bamford & Andrew Shaw - The Conversation 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Connor Bamford & Andrew Shaw, CVR postdoctoral researchers, posted a blog in 'The Conversation' about the need for research on highly pathogenic viruses to continue.

Blog writing helps to promote the breadth of research carried out by the CVR and again, raises our profile while helping our researchers meet their IMPACT targets. It's a great tool that enables researchers to reach a lay audience about engaging scientific information that's currently making the news headlines.


Connor Bamford has been invited to write further blogs for The Conversation.
Year(s) Of Engagement Activity 2014
URL https://www.facebook.com/centreforvirusresearch
 
Description Connor Bamford - The Conversation 11 March 2018 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact In March 2018 CVR postdoc Connor Bamford pitched an article for The Conversation. It was published and received subsequent social media coverage - https://theconversation.com/ebola-outbreak-in-drc-are-we-better-prepared-this-time-96368?fbclid=IwAR0taYRJ-Sd4z0frcGBhC5kKgAp8J5SXo8qasUooTGWJxCVLezWgUSwXCD4
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch
 
Description Connor Bamford - The Conversation 20 December 2018 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact In December 2018 CVR postdoc Connor Bamford was asked to write an article to provide expertise about the Ebola outbreak in the DRC. The Conversation has >100,000 readers. the article was shared on Facebook and Twitter receiving shares, comments and tweets/retweets.
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch/
 
Description Connor Bamford - The Conversation Oct 2014 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Connor Bamford, CVR postdoc, discusses the shipment of an experimental Ebola vaccine to West Africa in a blog in The Conversation.

Due to the popularity of Connor's blogs, he is now featured as a regular writer in this popular online publication.
Year(s) Of Engagement Activity 2014
URL http://theconversation.com/high-hopes-rest-on-800-vials-of-experimental-ebola-vaccine-shipped-from-c...
 
Description Connor Bamford Interview Nigerian International TV 14 May 2018 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact https://www.facebook.com/centreforvirusresearch

Postdoc Connor Bamford is interviewed on Live television and asked to provide commentary on the Ebola outbreak. Coverage was shared on CVR social media.
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch/
 
Description Connor Bamford and Andrew Shaw June 2018 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Connor Bamford and Andrew Shaw interview Dr Kevin Bakker, a postdoc in the lab of Dr Daniel Streicker here in Glasgow who currently works on how vampire bat rabies spreads between animals for a podcast and blog. the podcast received 88 listens and was shared on Facebook and Twitter to increase audience reach.

https://cvrblog.myportfolio.com/copy-of-following-viruses-using-digital-epidemiology

https://soundcloud.com/user-28288327/following-viruses-using-digital-epidemiology

4 page views
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch/
 
Description Connor Bamford and John McLauchlan - the Conversation October 2018 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Connor Bamford and John McLauchlan write a fascinating piece for The Conversation following a publication in PLOS Pathogens - https://bit.ly/2PGodds. The story was shared on Facebook and Twitter to highlight the article. The conversation has a readership of >100,000 people.
Link to the paper - https://bit.ly/2yUMu8z
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch/
 
Description Connor Bamford and Julien Amat - The Conversation 18 Jan 2018 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact https://theconversation.com/flu-why-this-years-outbreak-is-one-of-the-worst-89802

connor and Julien write about the 2018 flu outbreak and they are accepted for an article in the Conversation.
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch/
 
Description Connor Bamford, Jack Hirst and Andrew Shaw Blog and Podcast July 2018 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Connor Bamford, Jack Hirst and Andrew Shaw interview Professor Ian Goodfellow from the University of Oxford to hear about his career so far in virology and his recent work in helping stop viruses in Africa including during the recent West African Ebola outbreak. The interview was shared as a podcast and blog and shared on Facebook and Twitter. the podcast has had 90 listens on Soundcloud.

https://cvrblog.myportfolio.com/copy-of-fighting-viruses-across-africa-with-ian-goodfel

https://soundcloud.com/user-28288327/ian-goodfellow
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch/
 
Description Contagious Thinking podcast S2 ep6: Robert Gifford 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Dr. Robert Gifford, CVR's resident evolutionary virologist and senior research fellow. Rob's lab combines sequence data and software development to explore virus genomics and coevolution of viruses and their hosts. He applies virus genomics to help and guide treatment of HCV-infected patients; support genomic surveillance and outbreak response for bluetongue and rabies; and explore the diversity of endogenous viral elements in published genome sequence data, just to name a few of his projects. Listen to him tell us how he became interested in this paleovirology by starting out working on endogenous retroviruses at Imperial College long before the NGS metagenomics techniques come about.
Year(s) Of Engagement Activity 2019
URL https://cvrblog.myportfolio.com/podcast-s2-ep6-robert-j-gifford
 
Description Contagious Thinking podcast S2 ep7: Marlene Dreux 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact A podcast with Dr Marlene Dreux, Team Leader in immunovirology at the Centre International de Recherche en Infectiologie (CIRI) in Lyon, France.
Year(s) Of Engagement Activity 2019
URL https://cvrblog.myportfolio.com/podcast-s2-ep7-marlene-dreux
 
Description Contagious Thinking podcast S3 ep10: Laura McCoy 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact In this episode of Contagious Thinking Connor and Elihu are talking with Dr Laura McCoy about why study and continue to study broadly neutralizing antibodies against HIV, and the role of B cell biology in HIV infection and vaccine responses. She also discusses her career so far, and gives advice to PhD and early career researchers.
Year(s) Of Engagement Activity 2019
URL https://cvrblog.myportfolio.com/podcast-s3-ep10-laura-mccoy
 
Description Contagious Thinking podcast S3 ep11: Connor Bamford 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact In this episode, Jack Hirst and Andrew Burns (on his podcast debut) are joined by Contagious Thinking veteran and founder Connor Bamford, who is crossing to other side and telling us about his own research on a peculiar immune protein that seems to make Hepatitis C infections worse rather than better.
Year(s) Of Engagement Activity 2020
URL https://cvrblog.myportfolio.com/podcast-s3-ep11-connor-bamford
 
Description Contagious Thinking podcast S3 ep12: Diane Griffiths 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact In this episode we're extremely lucky to be welcoming Professor Diane Griffin, from the Johns Hopkins Bloomberg school of public health who is also the vice-president of the US National Academy of Sciences (www.nasonline.org/member-directoryers/3007695.html).

Diane - who is an MD/PhD - is a pioneering expert in how viruses cause disease, focusing on those viruses that infect your brain (like measles), and viruses spread by insects (like alphaviruses, such as Sindbis and chikunungya viruses).
Year(s) Of Engagement Activity 2020
URL https://cvrblog.myportfolio.com/podcast-s3-ep11-diane-griffin
 
Description Contagious Thinking podcast S3 ep1: Juan Fontana 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact This is the third season of the refreshing virology podcast. In this episode, we're starting off with Dr Juan Fontana, a structural biologist from the University of Leeds. Juan speaks with fellow postdoc Connor Bamford, about his career so far in Virology, how cryoEM works, and how he uses this technique to study deadly human viruses.
Year(s) Of Engagement Activity 2019
URL https://cvrblog.myportfolio.com/podcast-s3-ep1-juan-fontana
 
Description Contagious Thinking podcast S3 ep3: Paul Griffiths 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact In this episode we're welcoming Professor Paul Griffiths, from the Royal Free hospital and University College London. Professor Griffiths - who is a clinician by training - came to the CVR in Glasgow earlier this year to give a seminar.

Connor Bamford caught up with Paul in this episode and discuss his favourite virus, human cytomegalovirus (CMV), the road to making and testing vaccines against this very important virus, and his surprising side career as an author of factual and fictional science-inspired books.
Year(s) Of Engagement Activity 2019
URL https://cvrblog.myportfolio.com/podcast-s3-ep3-paul-griffiths
 
Description Contagious Thinking podcast S3 ep4: Pat Nuttall 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Season 3 Episode 3: This week Jack and Douglas are talking ticks with Professor Pat Nuttall, where we hear about how changing conditions are increasing the risk of tick-borne viruses and how these viruses benefit from the peculiar properties of tick saliva.
Year(s) Of Engagement Activity 2019
URL https://cvrblog.myportfolio.com/podcast-s2-ep4-pat-nuttall
 
Description Contagious Thinking podcast S3 ep5: Carolina Lopez 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact In this special episode for our Spanish speakers listeners, Mila and Elihu are talking with Carolina Lopez about how viruses interact with the immune system during infection. As viruses copy their genomes, a large number of defective copies are made. Carolina studies the different forms of a virus, including those with regular and defective copies of their genome, that are present in an infection and how these different forms interact with the infected cell and influence its function.
Year(s) Of Engagement Activity 2019
URL https://cvrblog.myportfolio.com/podcast-s3-ep5
 
Description Contagious Thinking podcast S3 ep6: Paul Lehner 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact In this episode of Contagious Thinking Jack and Arthur are talking with Professor Paul Lehner about HIV and silencing of these viruses by the newly discovered HUSH complex. Paul talks about his career so far and his research on HIV. He further explains how he and colleagues discovered the HUSH complex and its role in silencing viruses like HIV.
Year(s) Of Engagement Activity 2019
URL https://cvrblog.myportfolio.com/podcast-s3-ep6-paul-lehner
 
Description Contagious Thinking podcast S3 ep7: Rachel Ulferts 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact In this episode, Dr Connor Bamford speaks with Dr Rachel Ulferts from the Francis Crick Institute in London after she came to Glasgow recently to present her fascinating work.

Dr Ulferts is currently a postdoc in the lab of Dr Rupert Beale at the Crick where she works on influenza virus and a cell process known as autophagy - or 'self eating'.

Previously Rachel worked on a number of RNA viruses, like coronaviruses or picornaviruses in labs across Europe, including Northern Ireland and The Netherlands, before coming back to the UK to work at The University of Cambridge and then onto London.

In this episode Connor talks with Rachel about her work on autophagy, her interest in fundamental virology, and her exciting plans for the future.
Year(s) Of Engagement Activity 2019
URL https://cvrblog.myportfolio.com/podcast-s3-ep7-rachel-ulferts
 
Description Contagious Thinking podcast: Ann Palmenberg 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Professor Ann Palmenberg from the University of Wisconsin-Madison talking to us about her journey through academia as a virologist, her views on vaccines and women in science.
Year(s) Of Engagement Activity 2019
URL https://cvrblog.myportfolio.com/2019-stoker-award-winner-prof-ann-palmenberg
 
Description Contagious Thinking podcast: Siyuan Hu: A Tale of One City 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact In a very special ad hoc episode, we have the personal experience from the inside of the coronavirus outbreak. From mainland China in Wuhan City, fellow postdocs Elihu Araday and Rute Pinto talked with Siyuan Hu, a PhD student in the Professor Margaret Hosie's group, who is currently in Wuhan and living this outbreak from a different perspective.
Year(s) Of Engagement Activity 2020
URL https://cvrblog.myportfolio.com/siyuan-hu-a-tale-of-one-city
 
Description December 2016 Dr Connor Bamford 2016 Summary Blog 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Undergraduate students
Results and Impact In December 2016 Dr Connor Bamford produced a blog post to summarise blog and podcast activity for 2016 giving a round up of statistics and thanking our followers for engaging with our researchers' digital efforts.
http://cvr.academicblogs.co.uk/thanks-for-a-wonderful-2016-on-contagious-thinking/
We reached over 500 people with this post and have seen a steady increase in following for the blog and podcast archive.
Year(s) Of Engagement Activity 2016
URL https://www.facebook.com/centreforvirusresearch
 
Description December 2016 - Prof John McLauchlan - guest speaker at ICGEB meeting on Human RNA Viruses, Costa Rica 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Prof McLauchlan was invited as a guest speaker at ICGEB meeting on Human RNA Viruses, Costa Rica. The aim was to promote the CVR as an international centre for virological research, thus building external links and boosting the profile of the centre. This was an opportunity to engage with external Academic researchers and students.
Year(s) Of Engagement Activity 2016
 
Description December 2016 - Prof John McLauchlan Presentation - Scottish Society for Gastroenterology 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Prof McLauchlan presented a lecture on targets for new therapies for HCV infection and issues over drug resistance to clinicians. this was an opportunity to engage with key target audiences - Clinicians and academic researchers
Year(s) Of Engagement Activity 2016
 
Description December 2016 - Prof John McLauchlan UK Clinical Pharmacists Association - Masterclass on HCV Treatment, Manchester 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Prof McLauchlan presented a workshop on targets for new therapies for HCV infection to clinical pharmacists and issues over drug resistance. this was an opportunity to engage with key target audiences - Clinical Pharmacists, clinicians, healthcare professionals and pharmaceutical companies
Year(s) Of Engagement Activity 2016
 
Description December 2017 - CVR Public Engagement Awards 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact In December 2017 we presented 10 researchers involved in public engagement activity across the centre to recognise their efforts during the Christmas staff meeting as part of our commitment to reward and recognition. Recipients offered very positive feedback and were delighted to have their efforts recognised in front of their peers.
Year(s) Of Engagement Activity 2016,2017
URL https://www.facebook.com/centreforvirusresearch
 
Description December 2017 - Connor Bamford and David Robertson podcast and blog post 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact In December 2017 CVR postdoc Connor Bamford interviewed CVR's head of Bioinformatics Prof David Robertson to produce a podcast and blog post to mark World AIDS Day and to highlight the work of Prof Robertson in this field - https://cvrblog.myportfolio.com/copy-of-nothing-in-hiv-makes-sense-except-in-light-of-evolution. The post was shared on Facebook and Twitter reaching an audience of 605 with 3 shares on FB and reaching an audience of over 200 followers on Twitter. the podcast had 175 listens on SoundCloud. The blog post has been viewed 14 times. This perhaps indicates that followers may go straight to the podcast instead of reading the accompanying blog.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch
 
Description December 2017 - launch of new Contagious Thinking Blog and Podcast Website 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact In December 2017 CVR PhD student took on a project to make use of Adobe software to set up a new and improved website for the CVR Contagious Thinking blog and podcast. The software and website comprise a new, professional look and feel along with a more user-friendly and visual back catalogue for visitors to the site. We announced the new website on our social media channels with the launch of two blogs and podcast to mark World Aids Day. The posts reached over 1000 people on Facebook along with our 200 Twitter followers. The posts were also shared 4 times helping to give us wider audience distribution. Since the launched of the updated site on 1 December, it has received 1119 views by 332 users from all over the World.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch
 
Description Emma Thomson Press Release December 2018 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Dr Emma Thomson worked with Wellcome Sanger Institute collaborators to release a press release for a paper in December 2018. The paper was picked up by The Telegraph and the story shared on Facebook and Twitter receiving shares, retweets and comments - https://www.telegraph.co.uk/news/0/calls-tailored-treatment-new-strain-hep-c-found-uganda/?fbclid=IwAR2pWMwttq3lZL2bkW11HTwVcZ84A0CT0NZmdoFSSIs0CYjQnu3qehEut2Y

The press release was shared on the Wellcome Sanger Institute website - https://www.sanger.ac.uk/news/view/new-strains-hepatitis-c-found-africa?fbclid=IwAR3A8fCAAQl0spV7LDHUJx_qtFz54u33b78uPpxznig7esMJRoi1o-nW6S0
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch/
 
Description Engagement with support groups for HCV-infected patients 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? Yes
Type Of Presentation Keynote/Invited Speaker
Geographic Reach National
Primary Audience Participants in your research and patient groups
Results and Impact HCV Research UK has created a Steering Committee to oversee its activities. Patient support groups (HepC Trust and British Liver Trust) both have representatives on this committee. They are full members with the ability to comment on any plans for HCV Research UK. In addition, I have given oral presentations and led discussions with local and national HepC support groups (Hepatitis Scotland and Waverley Care).

Patient groups feel part of the study and will be able to give feedback to their relevant groups. In addition, it enabled patients to ask questions about the types of research and clinical studies on new anti-viral compounds.
Year(s) Of Engagement Activity 2011,2013
 
Description European Biobank conference, Vienna, Austria 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Industry/Business
Results and Impact Presented invited lecture on HCV Research UK to illustrate the sustainability of biobanks to an international audience.
Year(s) Of Engagement Activity 2016
 
Description February 2016 - Prof John McLauchlan Workshop/Presentation 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited speaker to the UK Clinical Pharmacists Association - Masterclass on HCV Treatment, London. Prof McLauchlan presented a workshop on targets for new therapies for HCV infection to clinical pharmacists and issues over drug resistance. This was an opportunity to engage with one of our key target audiences - the Pharmaceutical Industry.
Year(s) Of Engagement Activity 2016
 
Description February 2017 - CVR Science Writing Training Session 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Undergraduate students
Results and Impact In February 2017 one of our postdocs Dr Connor Bamford led a session with a group of researchers based at the CVR with an interest in science communications, writing and in making a contribution to the CVR blog. The session was an opportunity to identify and define our target audience along with agreeing a tone of voice to ensure consistency of approach. Our researchers were also able to make plans for content fort 2017.
Year(s) Of Engagement Activity 2016
 
Description February 2017 - Connor Bamford and Joanna Crispell Blog Post 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact In February 2017 CVR postdoc Connor Bamford and PhD student Joanna Crispell produced a blog post to share their experience of attending a Voice of Young Scientists Workshop. The post was viewed 18 times and was shared on Facebook and Twitter with a reach of over 400 followers.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch/
 
Description February 2017 - Elihu Aranday Cortes Huffington Post 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Dr Elihu Aranday Cortes, postdoc in the McLachlan lab, working on next-gen sequencing of dengue virus, writes about the continued threat from emerging viruses in Huffington Post Mexico. Importantly, Mexico has already a great burden of arboviruses, such as chikungunya, Zika and dengue viruses.
http://www.huffingtonpost.com.mx/elihu-aranday-cortes/luego-de-chikunguna-ebola-y-zika-que-epidemia-sigue/
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch
 
Description February 2017 - Voice of Young Scientists Media Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact In February 2017, Dr Connor Bamford, Joanna Crispell (CVR PhD student) and Siobhan Petrie (CVR Communications Officer) attended a Voice of Young Scientists Media Workshop at the University of Glasgow. The workshop was aimed at young researchers and focused on promoting confidence and techniques when working with journalists and the media. Connor and Joanna produced a very comprehensive blog post to share their experience and review of the workshop with other researchers.
http://cvr.academicblogs.co.uk/voys-sense-about-science-media-workshop/
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch
 
Description Glasgow Science Festival Science Sunday - June 2019 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact CVR researchers took a range of popular activities (build a virus, glovebox chamber game and Biolegomatics along to the Science Sunday event as part of the Glasgow Science Festival. 10 researchers from the CVR volunteered for the event and they estimated that they interacted with around 200 people over the course of the day. The activity was also supported by social media activity. MP Patrick Grady also made a point of visiting the stand to try an activity, take a photograph and tweet about the day. Stand visitors tend to have a keen interest in science but it is an opportunity for families to have a fun day out and learn something new.
Year(s) Of Engagement Activity 2019
URL https://twitter.com/CVRinfo/with_replies
 
Description HCV Research UK Launch January 2013 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? Yes
Geographic Reach National
Primary Audience Participants in your research and patient groups
Results and Impact HCV Research UK is a multi-disciplinary collaborative enterprise funded by a £1.92m grant from the Medical Research Foundation and based at the MRC-University of Glasgow Centre for Virus Research.

This ground breaking initiative has involved the development of a Bio-repository of clinical samples and cohort study of greater than 10,000 patients infected by Hepatitis C Virus (HCV).

The database of information gathered about this cohort group is supporting the work of STOP-HCV and is also influencing prescribing decisions taken by the NHS. The information is also being made available for future research into HCV infection, thereby influencing and creating greater funding opportunities for research in this disease area.
Year(s) Of Engagement Activity 2013,2014,2015
URL http://hcvresearchuk.org
 
Description HCV Research UK Press Release December 2014 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact In November of 2014, HCV Research UK, a consortium of experts in the field of Hepatitis C Virus who are leading a ground-breaking cohort study of Hepatitis C Virus infected patients, reached a landmark point in the project - recruiting 10,000 patients to the study ahead of their target date of the 31st December 2014. As a result of this success, we circulated a press release to the national press to share the news and also shared a story in the December edition of MRC Life.

The story featured in MRC Life, sharing this success story with other MRC Research Centres. The story was also features in the Viral Hepatitis in Practice publication in December 2014.
Year(s) Of Engagement Activity 2014
URL http://www.gla.ac.uk/researchinstitutes/iii/cvr/news/headline_391453_en.html
 
Description Hepatitis C Virus Origins Paper Press Release October 2015 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact Following the publication of a CVR paper, which demonstrated the origins of Hepatitis C virus in Scotland, we issued a press release for distribution to the media. This resulted in news stories in several news papers including The Scotsman, The Herald, The Independent and the Daily Express as well as a feature on the BBC news website. Carol Leitch (one of the authors) also took part in an interview with BBC Radio Scotland. Links to stories as follows:
http://www.bbc.co.uk/news/uk-scotland-34658098
http://www.thetimes.co.uk/tto/news/uk/scotland/article4599284.ece
http://www.scotsman.com/news/health/scientists-track-hepatitis-c-roots-in-scotland-1-3930369#axzz3pwgMI6mV
http://www.heraldscotland.com/news/homenews/13901425.Research_traces_hepatitis_C_infection_roots_to_Second_World_War/
http://www.thenational.scot/news/wartime-glasgow-study-offers-hope-in-hepatitis-c-battle.9
http://medicalxpress.com/news/2015-10-hepatitis-infections-scotland-wwii.html
Year(s) Of Engagement Activity 2015
URL https://www.facebook.com/centreforvirusresearch/
 
Description ICGEB meeting on Human RNA Viruses, Costa Rica 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Gave invited lecture and allowed advertising the CVR as an international centre for virological research.
Year(s) Of Engagement Activity 2016
URL http://www.icgeb.org/rna-virus-workshop-2016.html
 
Description Industrial workshop (Helena Biosciences) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited speaker to the launch of a new liver for liver disease that was aimed primarily at medical practitioners who provide clinical care to patients. This led to potential future avenues of research with the company involved.
Year(s) Of Engagement Activity 2019
 
Description Interviews 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact I have given interviews to journalists for newspapers.

There was no further contact with the journalists and so it is difficult to judge any impact.
Year(s) Of Engagement Activity 2006,2007
 
Description Invited Speaker at North of England Viral Hepatitis meeting 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited to present findings on possible resistance to new antiviral therapies for treating hepatitis C virus (HCV) infection to a group of clinicians, pharma representatives and nurses. Discussion centred on potential difficulties with natural strains that may be resistant and also retreatment for those patients in whom the drugs did not clear the virus.
Year(s) Of Engagement Activity 2017
 
Description Invited seminar speaker at the University of Hvidore, Denmark. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited to speak on the variability of hepatitis C virus (HCV) and the potential difficulties that this may pose for treating patients with new antiviral therapies. Discussion centred on the extent of variability of the virus as a possible problem for global eradication.
Year(s) Of Engagement Activity 2017
 
Description Invited speaker at UK Clinical Pharmacists Workshop 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact This was the third workshop by the UK Clinical Pharmacists to which I had been invited. The group wished to learn about the new therapies for treating hepatitis C virus infection and the success achieved by these therapies.
Year(s) Of Engagement Activity 2018
 
Description Invited speaker at a Gilead business event 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact The presentation was an update on possible resistance to novel antiviral therapies for treating hepatitis C virus (HCV) infection to the UK group of Gilead, a pharma company with drugs that have been approved for clinical use in HCV therapy.
Year(s) Of Engagement Activity 2017
 
Description Jack Hirst and Connor Bamford Blog and podcast June 2018 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact In June 2018 Jack Hirst and Connor Bamford interviewed Dr Yohei Yamauchi, University of Bristol about his research on influenza virus. the podcast was supported by a blog post and was shared on Facebook and Twitter - https://cvrblog.myportfolio.com/copy-of-unpacking-a-flu-virus

The podcast has had 160 listens on Soundcloud - https://soundcloud.com/user-28288327/yohei-edited#t=0:00

7 page views
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch
 
Description Jack Hirst, Connor Bamford and Andrew Shaw blog and Podcast June 2018 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Jack Hirst, Connor Bamford and Andrew Shaw interview Dr Gulsah Gabriel about his research on influenza virus. The podcast was supported by a blog and shared on Facebook and Twitter - https://cvrblog.myportfolio.com/copy-of-the-barriers-faced-by-flu-virus

The podcast has had 80 listens on Soundcloud - https://soundcloud.com/user-28288327/gulsah-edited

3 page views
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch/
 
Description Jan 2020 Steve Allman Mentoring session 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Postgraduate students
Results and Impact As part of the CVR's involvement in the MRC Festival of Medical Research, we participated in a mentoring session with a freelance public engagement consultant Steve Allman in collaboration with the MRC and our collaborators from Terence Higgins Trust. The session was designed to define and agree the objectives of the festival project while also allowing us to develop the activity and outline next steps.
Year(s) Of Engagement Activity 2020
 
Description January 2018 - Connor Bamford and Julien Amat - The Conversation 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact In January 2018 CVR postdoc Connor Bamford and PhD student Julien Amat collaborated on an article about the influenza outbreak for The Conversation. The article was published online and shared on the CVR Facebook and Twitter accounts. https://theconversation.com/flu-why-this-years-outbreak-is-one-of-the-worst-89802 The post reached over 2k followers on the CVR Facebook page alone with 24 shares. It has been one of our most popular and well read posts. The article also encouraged online Q&A on The Conversation website.
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch/
 
Description July 2016 - Prof John McLauchlan Western General Edinburgh Presentation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Prof McLauchlan presented a lecture on targets for new therapies for HCV infection and issues over drug resistance to clinicians and nursing staff. This activity allows us to engage with one of our key target audiences - NHS professionals along with subsequent information sharing with patients.
Year(s) Of Engagement Activity 2016
 
Description July 2017 - Connor Bamford and Jack Hirst Blog and Podcast 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact In July 2017 CVR postdoc Connor Bamford and PhD student Jack Hirst produced a blog post and interview covering an interview with Professor Jürgen Schwarze of the University of Edinburgh - http://cvr.academicblogs.co.uk/our-gut-microbes-and-parasites-are-protecting-us-against-viral-lung-infections/. The podcast had 125 listens with for 60 views for the blog post. The post was shared on social media reaching an audience of over 500 people on Facebook and Twitter.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch/
 
Description July 2017 - Hepatitis See Exhibition 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Patients, carers and/or patient groups
Results and Impact In July 2017 a group of CVR researchers attended an exhibition called Hepatitis See at the Glasgow Gallery of Modern Art. This was an invitation from the charity Hepatitis Scotland (who we had previously collaborated with) and an opportunity to engage with people who had previously attended an event for people affected by Hep C in 2016. We were asked to join the event as a result of social media promotion for the CVR colouring book. Our researchers took along pages of the book with craft materials, along with printed copies to share with visitors. This activity allowed our researchers to spend quality time with exhibition visitors and answer questions about their research.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch/
 
Description July 2017 - MRC Insight - Dr John McLauchlan 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact To mark World Hepatitis Day in July 2017, Dr John McLauchlan worked with the MRC to produce a blog post for MRC Insights highlighting the research of the CVR in this disease area. The blog post was shared on CVR and MRC social media channels with a reach of 980 contacts and 2 shares.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch/
 
Description July 2018 - World Hepatitis Day Blog post 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact To mark World Hepatitis Day, CVR postdocs Connor Bamford and Elihu Andaray-Cortez coordinated a photoshoot of CVR researchers involved in Hep C research across the centre. Photographs along with descriptions were shared as a blog post with a link on Facebook - https://cvrblog.myportfolio.com/world-hepatitis-day-2018

Approx 181 page views
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch/
 
Description June 2016 - Yasmin Parr and Connor Bamford Podcast 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Undergraduate students
Results and Impact CVR researchers Yasmin Parr and Connor Bamford interviewed Professor Richard Hardy for a podcast published in June 2016. The podcast was published on social media with an audience reach of >1000 people and 85 listens on soundcloud.

http://cvr.academicblogs.co.uk/what-do-you-mean-by-infectivity-a-conversation-with-richard-hardy/
Year(s) Of Engagement Activity 2016
URL https://www.facebook.com/centreforvirusresearch
 
Description June 2017 - Connor Bamford Eden Project Visit blog post 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact In June 2017 postdoc Connor Bamford visited the Eden project to provide support for a project called Virus Craft - http://cvr.academicblogs.co.uk/2017/06/. He produced a blog post to share his experience during the visit. the post had 62 views and reached over 500 people on Facebook and Twitter along with likes and shares.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch/
 
Description June 2017 - John McLauchlan - Press Commentary 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact In June 2017, Prof John McLauchlan responded to a controversial Hep C study for two news articles -
https://www.theguardian.com/society/2017/jun/13/hepatitis-c-antiviral-drugs-are-effective
http://www.dailymail.co.uk/health/article-4585694/Expensive-hepatitis-C-drug-does-not-cure-virus-study-says.html The articles were also shared on the CVR Facebook and Twitter channels reaching an audience of 781 followers with likes and 3 shares on Facebook, as well as reaching our audience of over 200 followers on Twitter.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch
 
Description Kelvingrove Museum Science Weekend 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? Yes
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact We ran our 'Build a virus' and 'One Infection' activities - offering participants the opportunity to learn all about the structure of viruses and also key messages related to the transmission of viruses, hygiene and vaccination.

Participants were asked to provide feedback on the activities to help us determine how to improve the activity in future. We have been asked to submit a proposal to run an activity during the Glasgow Science Festival in June 2015.
Year(s) Of Engagement Activity 2014
 
Description MRC Centenary Celebrations 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Type Of Presentation Workshop Facilitator
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Over the course of two events in June 2013, we interacted with approximately 350 children and their families. We used these interactions to communicate some basic facts about viruses - focussing on their size, structure, routes of transmission and how to limit spread. As part of the activity, we asked participants to consider the question 'If you were a virology researcher what would you study?' and collected responses using post-it note feedback. This provided a good opportunity to discuss the impact of medical research (we often used vaccines as an example), and the importance of the support of the Medical Research Council to help scientists tackle some of the greatest health problems facing humanity.

We have been invited to display the timeline at local schools and science centres across Scotland.
Year(s) Of Engagement Activity 2013
URL http://www.virusesacenturyofdiscovery.org.uk
 
Description MRC Festival of Medical Research 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Patients, carers and/or patient groups
Results and Impact The event was aimed at individuals infected with hepatitis C virus (HCV) as well as carers, professionals and national support groups for those infected with the virus. The day was planned to include talks on various topics relevant to HCV-infected individuals (new treatments, likely outcomes, liver disease) and how the CVR was addressing these themes in its research portfolio. Feedback on the event was universally positive from those who attended.
Year(s) Of Engagement Activity 2016
 
Description MRC Insight Publication 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Blog for MRC Insight to update activities associated with HCV Research UK and STOP-HCV.
Year(s) Of Engagement Activity 2015
URL http://www.insight.mrc.ac.uk/2015/07/28/finding-the-right-treatment-for-patients-with-hepatitis-c/
 
Description MRC Life - John McLachlan July 2015 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? Yes
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact The article was posted on our Facebook and Twitter pages and encouraged online comments and likes.

No notable impact.
Year(s) Of Engagement Activity 2015
URL https://www.facebook.com/centreforvirusresearch/
 
Description MRC Parliamentary Event 6 February 2019 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact The CVR participated in the MRC parliamentary event on 6 February 2019. This event was coordinated by the MRC Executive and was hosted by Lewis MacDonald MSP. Invitations were extended to all MSPs by the MRC. Richard Lochhead, Minister for Further Education, Higher Education and Science attended and gave a short speech. Cabinet Secretary for Health and Sport, Jeane Freeman also attended. From the CVR Alain Kohl, Claire Donald and Ben Brennan displayed at a stand with a poster, film clip of mosquitoes and augmented reality viruses with tablets. Massimo Palmarini and John McLauchlan attended as guests in the room. The CVR also extended the invitation to Vice Principal for Research Prof Miles Padgett, Dean for Research Prof Graeme Milligan and Head of Institute Prof Iain McInnes. In the run up to the event, the CVR followed up with 9 MSPs informing of our presence at the event. We received positive responses from Miles Briggs and Patrick Grady.
Year(s) Of Engagement Activity 2019
URL https://www.facebook.com/centreforvirusresearch/
 
Description March 2017 - Connor Bamford and Andrew Shaw Blog and Podcast 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact In March 2017 CVR postdocs Connor Bamford and Andrew Shaw produced a blog http://cvr.academicblogs.co.uk/2017/03/ and podcast to share an interview with Professor Jan Rehwinkel from the University of Oxford and MRC Human immunology unit. The blog post had 44 views and the podcast had 139 listens. The post was shared on Facebook and Twitter reaching an audience of over 700 people along with likes and shares.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch/
 
Description March 2017 - MRC Technology Hep C Vaccine Press Release 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact MRC Technology, a medical research charity, has announced it has licensed an antibody to Newsummit Biopharma - a leading China-based drug development process solutions provider, for development of a novel therapeutic for treatment of Hepatitis C virus (HCV) infection. The antibody was humanised by MRC Technology scientists, and originated in the laboratory of Prof. Arvind Patel.
A press release was produced by MRC Technology in collaboration with Newsummit Biopharma and Prof Patel and the story shared on social media channels. It has been picked up widely by a range of news channels:
http://www.mrctechnology.org/mrc-technology-licenses-antibody-to-newsummit-biopharma-for-development-of-hepatitis-c-virus-infection-therapeutic/
http://www.zymecommunications.com/1518/mrc-technology-licenses-antibody-to-newsummit-biopharma-for-development-of-hepatitis-c-virus-infection-therapeutic/
https://www.manufacturingchemist.com/news/article_page/MRC_Technology_licenses_antibody_for_HCV_therapeutic/126988
https://www.thepharmaletter.com/article/mrc-licences-antibody-to-newsummit-biopharma-to-develop-hcv-therapy
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch
 
Description March 2017 - Training workshop for Abbvie Medical Team at CVR 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact In March 2017, Prof John McLauchlan and members of his research group delivered a series of presentations, Q&A and a lab tour for a group of staff working in the Abbvie Medical Team. This was a key opportunity to engage with one of our key target audiences - the pharmaceutical industry. Attendees reported finding the information very important and found it to be a very important development opportunity.
Year(s) Of Engagement Activity 2017
 
Description Meet the Researcher Showcase Event Feb 2020 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Ilaria Epifano and Michaela Conley attended a two day event that took place in both the Dundee and Glasgow Science centres to run an exhibition attended by 200 Higher Biology School pupils from across Scotland each day. Our researchers used our build a virus activity to engage in conversation and took leaflets to share information about entering a career in virology. They estimate that they engaged with around 100 school pupils each day.
Year(s) Of Engagement Activity 2020
URL https://www.facebook.com/centreforvirusresearch/
 
Description NHS Research Scotland conference, QEUH, Glasgow 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Invited lecture on STOP-HCV and HCV Research UK to demonstrate benefits of stratified medicine for treating HCV infection.
Year(s) Of Engagement Activity 2016
 
Description National Forum for HCV 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presented data on resistance identified in patients receiving new therapies for HCV infection to inform a national group about the possible importance of resistance testing.
Year(s) Of Engagement Activity 2016
 
Description November 2016 - Prof John McLauchlan Guest Speaker University of Leicester 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact In November 2016 Prof McLauchlan delivered a talk at the University of Leicester on how different disciplines impact on virus research to Undergraduates taking interdisciplinary degree. This activity with our objective to promote virology as a career option for younger people and scientists.
Year(s) Of Engagement Activity 2016
 
Description November 2017 - Connor Bamford and Shirin Ashraf - The Conversation 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact CVR postdocs Connor Bamford and Shirin Ashraf write for The Conversation about the Marburg virus outbreak - https://theconversation.com/marburg-virus-outbreak-in-uganda-what-you-need-to-know-87065?utm_source=twitter&utm_medium=twitterbutton
The story was re-shared online by The Independent - http://www.independent.co.uk/life-style/health-and-families/marburg-virus-outbreak-in-uganda-what-you-need-to-know-a8051966.html
The article and subsequent news story were both shared on CVR Facebook and Twitter channels reaching an audience of over 1000 followers along with likes, shares and comments.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch
 
Description November 2017 - Elihu Andaray-Cortes - The Huffington Post Mexico 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact In November 2017 CVR postdoc Elihu Aranday-Cortes produced an article which was published in the Huffington Post Mexico about the constant threat of antimicrobial resistance.http://www.huffingtonpost.com.mx/elihu-aranday-cortes/el-mundo-no-acaba-con-un-estallido-sino-con-una-bacteria-mult_a_21876608/ Mexico is the World's largest Spanish-speaking country in the world followed by the USA and this online forum attracts a large audience. The post reached over 300 followers the CVR Facebook page as well as with over 200 Followers on Twitter.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch/
 
Description November 2017 - Shirin Ashraf and Connor Bamford - The Conversation 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact In November 2017, CVR postdocs Shirin Ashraf and Connor Bamford produced an article about the Marberg virus outbreak for The Conversation - https://theconversation.com/marburg-virus-outbreak-in-uganda-what-you-need-to-know-87065?utm_source=twitter&utm_medium=twitterbutton. The article then went on to be picked up an reposted online by The Independent - http://www.independent.co.uk/life-style/health-and-families/marburg-virus-outbreak-in-uganda-what-you-need-to-know-a8051966.html. The story was picked up by over 5000 followers on our Facebook channel alone, providing fantastic widespread exposure for our researchers and the CVR.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch
 
Description October 2016 - Dr Connor Bamford HIV Blog Post 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact In October 2016 Dr Connor Bamford published a blog about HIV research for the CVR blog. The post was shared on social media reaching an audience of 555 on Facebook. Blog posts encourage online commentary and questions.
Year(s) Of Engagement Activity 2016
URL https://www.facebook.com/centreforvirusresearch/
 
Description October 2016 - Prof John McLauchlan lecture at NHS Research Scotland conference, QEUH, Glasgow 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Professional Practitioners
Results and Impact Prof McLauchlan delivered a presentation on STOP-HCV to demonstrate benefits of stratified medicine for treating HCV infection. this was an opportunity to share information and engage with Clinicians and academic researchers.
Year(s) Of Engagement Activity 2016
 
Description October 2017 - Connor Bamford and Daniel Streicker blog post and podcast 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Following a successful podcast and blog featuring an interview with Dr Daniel Streicker during October 2016, CVR postdoc Connor Bamford interviewed Principal Investigator Daniel Streicker to share an update on his research into a popular topic: viruses carried by vampire bats in Peru - http://cvr.academicblogs.co.uk/back-with-the-vampires-in-peru/ The blog post and podcast were shared on social media engaging 33 blog views, 109 listens on SoundCloud and a reach of over 400 followers on the CVR Facebook and 10 shares demonstrating a 40% response rate on Facebook alone.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch/
 
Description October 2017 - Connor Bamford and Elihu Andaray-Cortes Blog post and podcast 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact In October 2017 CVR Postdocs Connor Bamford and Elihu Andaray-Cortes publish a blog post and podcast featuring an interview with a high-profile external guest speaker - http://cvr.academicblogs.co.uk/all-about-antivirals-the-arbidol-story/. The podcast received 111 listens on SoundCloud, 41 listens on the blog site and was shared on social media reaching an audience of over 400 followers on social media.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch/
 
Description Outbreak: The Pub Quiz 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Join scientists from the Centre for Virus Research for some infectious fun at this pub quiz! Scientists will share their expertise and challenge your knowledge about the viruses hitting the headlines
Year(s) Of Engagement Activity 2019
 
Description PCR workshop - Glasgow Science Centre 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact The workshop was organised by Dr D Bhella from the Unit and he will no doubt provide more comprehensive details. Both of the CDFs employed on the project volunteered their time and expertise for the workshop.

As noted above, Dr D Bhella will most likely address this question on behalf of the Unit.
Year(s) Of Engagement Activity 2009
 
Description PHE HCV Drug Resistance Group for DAA Therapy 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Public Health England (PHE) created a working group to establish guidelines for retreatment of HCV-infected patients who had been treated with novel all-oral therapy but treatment was not successful.
Year(s) Of Engagement Activity 2018,2019,2020
URL https://www.gov.uk/government/publications/antiviral-resistance-testing-in-the-management-of-hepatit...
 
Description Pablo Murcia Press Release December 2019 
Form Of Engagement Activity A press release, press conference or response to a media enquiry/interview
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact To highlight a paper in PLoS Pathogens, Pablo Murcia & Sema Nickbaksh worked with the UofG and MRC press teams to produce a press release to highlight this new research paper. The press release was shared across CVR, UofG and MRC social media channels to increase audience reach. The story received extensive media coverage.
Year(s) Of Engagement Activity 2019
URL https://www.facebook.com/centreforvirusresearch/
 
Description Patient Group Conference 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Patients, carers and/or patient groups
Results and Impact Hepatitis Scotland organised a national event (Hepatitis See) for patient groups across Scotland. I was an invited speaker and the presentation highlighted the importance of the scientific community to curing virus infection.
Year(s) Of Engagement Activity 2018
URL https://www.eventbrite.co.uk/e/hepatitis-see-a-patient-conference-tickets-50681251989#
 
Description Presentations to school children 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? Yes
Geographic Reach Regional
Primary Audience Schools
Results and Impact Formal presentation by PhD students to sixth form school children about their research projects at Glasgow Science Centre (2006 and 2008). Also regular contributions made by team members to workshops and demonstrations at Glasgow Science Centre and the Edinburgh Science Fair. Team members have also participated regularly in workshops at Schools Open Days hosted by our establishment (MRC Virology Unit)

These activities have encouraged gifted school children about science. The formal talks in particular were very positively received by both pupils and teachers.
Year(s) Of Engagement Activity 2006,2007,2008,2009
 
Description Scottish Society for Gastroenterology 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presented lecture on targets for new therapies for HCV infection and issues over drug resistance to clinicians at a national conference.
Year(s) Of Engagement Activity 2016
 
Description September 2016 - Connor Bamford Podcast with Prof Palmarini and Eleonora Meliz (CVR PhD Student) 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact Dr Connor Bamford interviewed our Director, Professor Massimo Palmarini and CVR PhD student Eleonora Melzi for a podcast published in September 2016.
http://cvr.academicblogs.co.uk/architectural-antagonism-by-an-acute-arbovirus/
The post reached >400 people on social media with 71 people listening to the podcast on soundcloud
Year(s) Of Engagement Activity 2016
URL https://www.facebook.com/centreforvirusresearch
 
Description September 2016 - Dr Connor Bamford CVR Podcast 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact In September 2016 CVRpostdoc Dr Connor Bamford produced a podcast and accompanying blog post for the CVR academics blog -
http://cvr.academicblogs.co.uk/architectural-antagonism-by-an-acute-arbovirus/
71 people listened to the podcast, which was also shared on social media.
Year(s) Of Engagement Activity 2016
URL https://www.facebook.com/centreforvirusresearch
 
Description September 2016 - Prof John McLauchlan lecture at European Biobank conference, Vienna, Austria 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Prof McLauchlan presented a lecture on HCV Research UK to illustrate the sustainability of biobanks. This was an opportunity to engage with key audiences including - Academic researchers and other disciplines (e.g. ethics and those involved in national programmes for biobanking.
Year(s) Of Engagement Activity 2016
 
Description September 2016 - Prof John McLauchlan lecture at Sheila Sherlock Updates, Royal Free London 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact In September 2016 Prof McLauchlan presented a lecture on targets for new therapies for HCV infection and issues over drug resistance to clinicians and academic staff. The aim of this activity was to share CVR research and expertise with external peers in the interests of promoting partnership working and collaboration.
Year(s) Of Engagement Activity 2016
 
Description September 2016 - Undergraduate Student Public Engagement Placement 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact In September 2016, CVR postdoc Connor Bamford accepted an invitation to support a placement for an undergraduate microbiology student Josie Bellhouse. Josie came to work at the CVR on a part-time basis and completed a project focusing on public engagement as part of a project. Josie designed her project focussing on a questionnaire designed for CVR and University of Glasgow researchers and undergraduate students to assess attitudes on public engagement and barriers to involvement. Josie also designed a separate questionnaire for members of the public and took this to Explorathon at the Glasgow Science Centre. Josie also used the placement as an opportunity to produce to podcasts for the CVR blog. This was shared on social media via targeted marketing.

Josie produced a report of her findings, which have subsequently been taken into consideration for the CVR 5 year strategy and annual communication plan. We also presented a summary of her findings during a presentation at the CVR staff meeting.
Year(s) Of Engagement Activity 2016
 
Description September 2017 Ed Hutchinson and Connor Bamford - Art School Graduate Degree Show Blog Post 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Undergraduate students
Results and Impact In August 2017, Dr Ed Hutchinson provided support to a Glasgow School of Art student completing an MSc in Medical Visualisation and Human Anatomy in a course run jointly with the University of Glasgow. The focus of Naina Nair's project was to take structural representations of influenza and represent in an artistic format as an exhibit for the show. Ed worked with postdoc Connor Bamford to produce a blog post to highlight the project - http://cvr.academicblogs.co.uk/1344-2/, which was viewed 273 times. The post was also shared on CVR social media channels reaching an audience of >500 followers.
Year(s) Of Engagement Activity 2017
URL https://www.facebook.com/centreforvirusresearch/
 
Description September 2018 - Connor Bamford and Betty Lau blog post 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact CVR postdoc Connor Bamford published a blog post written by postdoc Betty Lau to highlight a visit from Prof Kawaoka winner of the 2018 Sir Michael Stoker Award. The post was shared on Facebook and Twitter -

https://cvrblog.myportfolio.com/visit-from-prize-winner-prof-kawaoka

the post will be followed up by a podcast in future.
Year(s) Of Engagement Activity 2018
URL https://www.facebook.com/centreforvirusresearch/
 
Description Sheila Sherlock Updates, Royal Free London 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Presented invited lecture on targets for new therapies for HCV infection and issues over drug resistance to clinicians and academic staff.
Year(s) Of Engagement Activity 2016
 
Description Showcase Event - HCV Research UK 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The event was organised by the British Association for Study of the Liver/British Viral Hepatitis Groups to showcase consortia involved in HCV infection but primarily HCV Research UK. The purpose was to demonstrate the impact of HCV Research UK at the national level on collecting data and clinical samples to promote research into the virus, in particular with reference to the new therapies now available for treatment.
Year(s) Of Engagement Activity 2015
 
Description Sun Yat-Sen University, Guangzhou, China 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Invited lecture to promote collaboration between CVR and Sun Yat-Sen University. The outcome was a collaboration with the Guangzhou Blood Centre, which led to a 1 year working visit by a senior member of their staff to the CVR.
Year(s) Of Engagement Activity 2016
 
Description UK Clinical Pharmacists Association - Masterclass on HCV Treatment #1 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The workshop was aimed at clinical pharmacists to broaden their knowledge of new therapies for HCV infection and issues over drug resistance. Feedback from the event was that the presentation improved knowledge of new therapies and issues over their use.
Year(s) Of Engagement Activity 2016,2017,2018
 
Description UK Clinical Pharmacists Association - Masterclass on HCV Treatment #2 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact The workshop was aimed at clinical pharmacists to broaden their knowledge of new therapies for HCV infection and issues over drug resistance. Feedback from the event was that the presentation improved knowledge of new therapies and issues over their use.
Year(s) Of Engagement Activity 2016
 
Description University of Leicester 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Undergraduate students
Results and Impact Presentation on how different disciplines impact on virus research.
Year(s) Of Engagement Activity 2016
 
Description presentation 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact I have given a presentation to a HepC support group and been involved in fund-raising activities.

Support groups are more aware of the activities funded by MRC to study HCV infection
Year(s) Of Engagement Activity 2006
 
Description presentations 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact I have given practical demonstrations and talks at open days for schools.

There are now well-established contacts with local schools and teachers. Students have expressed a greater interest in pursuing a scientific career after the open day events.
Year(s) Of Engagement Activity 2006,2007,2008