Standards for determining the vascular contribution to neurodegeneration
Lead Research Organisation:
University of Edinburgh
Department Name: Sch of Molecular. Genetics & Pop Health
Abstract
There are many causes of cognitive decline and dementia with ageing. The common causes tend to overlap, aren't well understood and have a similar appearance on imaging. Many of the imaging features are not well-defined. We are establishing a worldwide group of experts to create a common language for describing the imaging features and conducting imaging research in order to define the role of blood vessels in dementia.
Technical Summary
Neurodegeneration during ageing is commonly associated with neuroimaging features of small vessel disease (SVD): lacunes, leukoaraiosis, enlarged perivascular spaces, microbleeds, brain atrophy. These exacerbate, and are closely interrelated with, cognitive impairment, disability and dementia arising from neurodegeneration. The terminology and definitions used to describe these common imaging features vary widely, impairing clinical characterisation and subject phenotyping. This is a major barrier to progress in determining the full pathophysiology of neurodegeneration plus the contribution that SVD makes to the clinical expression of common neurodegenerative diseases and to their cause. The COEN Initiative represents, par excellence, a timely opportunity to establish a collaborative expert network to agree standard definitions and terminologies for SVD on neuroimaging, provide easy-to-access exemplars, suggested image acquisition and analysis protocols and standards for reporting of studies to optimise future research. The investigators bring complementary multidisciplinary expertise on clinical imaging of neurodegeneration from cerebrovascular, Alzheimer's disease, and ageing perspectives. UK, German and Canadian COEN experts plus external collaborators will undertake two workshops, prepare and test agreed exemplars and advisory materials. The proposed work is not being undertaken elsewhere yet is essential for improved phenotyping to advance future epidemiology, genetic, pathology research and clinical trials in the commonest neurodegenerative disorders.
Planned Impact
Intellectual property: The project is unlikely to generate intellectual property, although the initiative could lead to intellectual property in the future. However this would require more funding and would be covered under specific agreements. In the unlikely event that any intellectual property is generated, all host institutions have technology transfer offices that are able to manage such work. In the case of Edinburgh, there is already a substantial investment from MRC in technology transfer activities and these have been highly successful.
Dissemination: Plans for dissemination include peer-review journal publications, materials downloadable from partner and key society websites, and specific symposia in which the outputs from the workshops can be fed back to the community that is most critically interested at international conference symposia that will be taking place around the end of the project. The major peer-review publication will be targeted at, for example, Lancet Neurology. Materials such as an agreed set of descriptors of neuroimaging features of SVD, qualitative and quantitative rating tools and guidance on their use, imaging examples of SVD, standards for image acquisition, standards for scientific reporting of methods, analysis and results of studies on age-related SVD and neurodegeneration, bibliographies of relevant papers, datasets, analysis software and teaching materials and advisory core standards for data collection in future studies of neurodegeneration and SVD can all be made available on websites, in addition to publication in journals where appropriate. International conferences taking place around the end of the project period include the International Society for Vascular and Cognitive Behavioural Disorders (VasCog), taking place in Toronto, June 2013. Local Organising Committee lead S Black has already suggested a symposium to describe and discuss the project outputs should take place within the VasCog 2013 programme. We will also
propose a symposium on SVD at the European Stroke Conference May 2013, likely just before the end of the project, but timely for final feedback. We will endeavour to have guidance on standards for scientific reporting of methods, analysis and results of studies on age-related SVD and neurodegeneration in a form that can easily be incorporated into relevant journal instructions for authors and on the Equator website (http://www.equator-network.org/).
Dissemination: Plans for dissemination include peer-review journal publications, materials downloadable from partner and key society websites, and specific symposia in which the outputs from the workshops can be fed back to the community that is most critically interested at international conference symposia that will be taking place around the end of the project. The major peer-review publication will be targeted at, for example, Lancet Neurology. Materials such as an agreed set of descriptors of neuroimaging features of SVD, qualitative and quantitative rating tools and guidance on their use, imaging examples of SVD, standards for image acquisition, standards for scientific reporting of methods, analysis and results of studies on age-related SVD and neurodegeneration, bibliographies of relevant papers, datasets, analysis software and teaching materials and advisory core standards for data collection in future studies of neurodegeneration and SVD can all be made available on websites, in addition to publication in journals where appropriate. International conferences taking place around the end of the project period include the International Society for Vascular and Cognitive Behavioural Disorders (VasCog), taking place in Toronto, June 2013. Local Organising Committee lead S Black has already suggested a symposium to describe and discuss the project outputs should take place within the VasCog 2013 programme. We will also
propose a symposium on SVD at the European Stroke Conference May 2013, likely just before the end of the project, but timely for final feedback. We will endeavour to have guidance on standards for scientific reporting of methods, analysis and results of studies on age-related SVD and neurodegeneration in a form that can easily be incorporated into relevant journal instructions for authors and on the Equator website (http://www.equator-network.org/).
Organisations
- University of Edinburgh (Lead Research Organisation)
- Lille University Hospital (Collaboration)
- University Medical Center Rotterdam (Collaboration)
- University of Calgary (Collaboration)
- Alberta Health Services (Collaboration)
- University of Iceland (Collaboration)
- Massachusetts General Hospital (Collaboration)
- University of Laval (Collaboration)
- McMaster University (Collaboration)
- Leiden University Medical Center (Collaboration)
- UNSW Sydney (Collaboration)
- University Medical Center Utrecht (UMC) (Collaboration)
- Ludwig Maximilian University of Munich (LMU Munich) (Collaboration)
- University of Florence (Collaboration)
- UNIVERSITY OF LEEDS (Collaboration)
- Chinese University of Hong Kong (Collaboration)
- Utrecht University (Collaboration)
- UNIVERSITY OF SYDNEY (Collaboration)
- Aarhus University (Collaboration)
- University College London (Collaboration)
- McGill University (Collaboration)
- Erasmus MC (Collaboration)
- The Otto-von-Guericke University Magdeburg (Collaboration)
- Lariboisière Hospital (Collaboration)
- German Centre for Neurodegenerative Diseases (Collaboration)
- IMPERIAL COLLEGE LONDON (Collaboration)
- University of California, Davis (Collaboration)
- University Hospital Carl Gustav Carus Dresden (Collaboration)
- Maastricht University Medical Center+ (Collaboration)
- Boston University (Collaboration)
- Western University (Collaboration)
- Radboud University Nijmegen Medical Center (Collaboration)
- University of Bordeaux (Collaboration)
- Medical University of Graz (Collaboration)
- National University of Singapore (Collaboration)
- University of Toronto (Collaboration)
- National Institutes of Health (NIH) (Collaboration)
- University of Bonn (Collaboration)
Publications
Al-Shahi Salman R
(2019)
Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial.
in The Lancet. Neurology
Appleton JP
(2020)
Imaging markers of small vessel disease and 'brain frailty' and outcomes in acute stroke
in Neurology
Aribisala BS
(2020)
Sleep and brain morphological changes in the eighth decade of life.
in Sleep medicine
Aribisala BS
(2023)
Sleep quality, perivascular spaces and brain health markers in ageing - A longitudinal study in the Lothian Birth Cohort 1936.
in Sleep medicine
Ball EL
(2023)
Predictors of post-stroke cognitive impairment using acute structural MRI neuroimaging: A systematic review and meta-analysis.
in International journal of stroke : official journal of the International Stroke Society
Ballerini L
(2020)
Quantitative measurements of enlarged perivascular spaces in the brain are associated with retinal microvascular parameters in older community-dwelling subjects.
in Cerebral circulation - cognition and behavior
Ballerini L
(2018)
Perivascular Spaces Segmentation in Brain MRI Using Optimal 3D Filtering.
in Scientific reports
Bastin M
(2019)
Polygenic architecture of human neuroanatomical diversity
in Cerebral Cortex
| Description | "Clinician training partnership: vascular contribution to dementia": Clinical Training Partnership awarded to W Whiteley, JM Wardlaw, G Hardingham, CW Ritchie, C Smith, A Williams, K Horsburgh, H Whalley, S Munoz Maniega |
| Amount | £225,000 (GBP) |
| Funding ID | 3699 |
| Organisation | Alzheimer's Society |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2019 |
| End | 07/2022 |
| Description | "Perivascular spaces: an early marker of vascular contributions to neurodegeneration": JM Wardlaw (PI), S Black, G-J Biessels, F Chappell, MV Hernandez, L Ballerini, J Ramirez, H Kuijf. |
| Amount | £39,768,500 (GBP) |
| Funding ID | UB190097 |
| Organisation | Weston Brain Institute |
| Sector | Private |
| Country | Canada |
| Start | 03/2020 |
| End | 03/2021 |
| Description | "Small Vessel Disease - Spotlight on Symptoms (SVD-SOS) - Improving recognition of symptoms and signs of progressing cerebral small vessel disease-related brain damage to prevent cognitive decline, dementia and stroke" (Doubal F, Wardlaw, JM) |
| Amount | £24,962,394 (GBP) |
| Funding ID | SA PG 19\100068 |
| Organisation | Stroke Association |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2019 |
| End | 07/2022 |
| Description | BHF Research Excellence Award |
| Amount | £3,000,000 (GBP) |
| Organisation | British Heart Foundation (BHF) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2019 |
| End | 04/2024 |
| Description | BHF-Turing Cardiovascular Data Science Award "Uncovering retinal microvascular predictors of compromised brain haemodynamics in small vessel disease"; MO Bernabeu Llinares, JM Wardlaw, SJ Wiseman, T MacGillivray, R Sarkar, F Doubal |
| Amount | £110,000 (GBP) |
| Funding ID | BHF-Turing-19/2/1038 |
| Organisation | British Heart Foundation (BHF) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2019 |
| End | 12/2021 |
| Description | EC Horizon 2020: Small vessel diseases in a mechanistic perspective: targets for intervention affected pathways and mechanistic exploitation for prevention of stroke and dementia (SVDs@Target) |
| Amount | € 6,000,000 (EUR) |
| Funding ID | 666881 |
| Organisation | European Commission |
| Sector | Public |
| Country | European Union (EU) |
| Start | 01/2016 |
| End | 12/2020 |
| Description | EPSRC Research Grant |
| Amount | £1,100,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 05/2018 |
| Description | EU Joint Programme - Neurodegenerative Disease Research |
| Amount | € 47,416 (EUR) |
| Organisation | EU Joint Programme - Neurodegenerative Disease Research (JPND) |
| Sector | Public |
| Country | European Union (EU) |
| Start | 09/2014 |
| End | 03/2015 |
| Description | Fondation Leducq Transatlantic Networks of Excellence Program |
| Amount | $6,000,000 (USD) |
| Funding ID | 16 CVD 05 |
| Organisation | The Leducq Foundation |
| Sector | Charity/Non Profit |
| Country | France |
| Start | 09/2016 |
| End | 09/2021 |
| Description | Innovate-UK |
| Amount | £1,048,661 (GBP) |
| Organisation | Innovate UK |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 03/2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Amount | € 49,855 (EUR) |
| Organisation | EU Joint Programme - Neurodegenerative Disease Research (JPND) |
| Sector | Public |
| Country | European Union (EU) |
| Start | 01/2017 |
| End | 12/2017 |
| Description | Row Fogo Centre for Research into Ageing and The Brain |
| Amount | £313,717 (GBP) |
| Organisation | The Row Fogo Charitable Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2018 |
| End | 08/2021 |
| Description | SINAPSE PEER |
| Amount | £6,000 (GBP) |
| Organisation | Scottish Imaging Network: A Platform for Scientific Excellence (SINAPSE) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 09/2016 |
| Description | SINAPSE PEER |
| Amount | £6,000 (GBP) |
| Organisation | Scottish Imaging Network: A Platform for Scientific Excellence (SINAPSE) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 06/2015 |
| Description | UK Dementia Research Initiative - "Small vessel diseases and vascular contributions to neurodegeneration and dementia" |
| Amount | £1,499,996 (GBP) |
| Funding ID | UKDRI-4002 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2017 |
| End | 08/2022 |
| Title | Cerebrovascular Diseases Image Databank |
| Description | The Database contains brain magnetic resonance & computed tomographic imaging data from patients with cerebrovascular diseases. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| Impact | The patients with cerebrovascular diseases participated in a range of individual specific research projects & clinical trials on stroke, dementia or other aspects of cerebrovascular disease, or attended for brain imaging as part of routine clinical care & agreed to donate their imaging to the Database, from 1998 onwards. The data were linked in 2016 with Scottish Central Health Records & include long term outcomes up to 19 years. |
| URL | https://www.ed.ac.uk/clinical-sciences/edinburgh-imaging/research/themes-and-topics/analysis-and-pro... |
| Title | Digital Brain Atlases for Assessing Markers of Cerebral Small Vessel Disease |
| Description | Datasets that include the reference brain template where atlases have been developed, & the brain atlases for assessing different markers of cerebral small vessel disease & neurodegeneration. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| Impact | Includes two datasets: Digital brain atlas Regional brain atlas for assessment of enlarged perivascular spaces This dataset contains a reference brain-extracted T1-weighted structural magnetic resonance image, representative of a normal brain from an individual in the first half of the 80th decade of life (70 to 75 years old), & the correspondent binary masks of the regions identified as being primary & the most eloquent sites of finding enlarged perivascular spaces, namely 1) midbrain & pons, 2) basal ganglia & 3) centrum semiovale & deep corona radiata supraventricular. Author: Valdés Hernández, Maria. Regional brain atlas for assessment of white matter hyperintensities This dataset contains a reference brain-extracted T1-weighted structural magnetic resonance image, representative of a normal brain from an individual in the first half of the 80th decade of life (70 to 75 years old), & the correspondent binary masks of the regions identified as relevant for studying white matter hyperintensities. Authors: Jackson, Michael R.; Valdés Hernández, Maria. |
| URL | https://www.ed.ac.uk/clinical-sciences/edinburgh-imaging/research/themes-and-topics/analysis-and-pro... |
| Title | Measurements of a perivascular spaces magnetic resonance imaging physical phantom and correspondent digital reference object model, 2023 [dataset] |
| Description | Duarte Coello R, Valdés Hernández MC, Ballerini L, Bernal Moyano J, Chappell FM, Brown R, Wardlaw JM, Zwanenburg J, Van Der Velden M, Kuijf HJ. (2023). Measurements of a perivascular spaces magnetic resonance imaging physical phantom and correspondent digital reference object model, 2023 [dataset]. University of Edinburgh. Centre for Clinical Brain Sciences. Department of Neuroimaging Sciences. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2023 |
| Provided To Others? | Yes |
| Impact | N/A. |
| URL | https://datashare.ed.ac.uk/handle/10283/8465 |
| Title | On the detectability and accuracy of computational measurements of enlarged perivascular spaces from magnetic resonance images" (under review). |
| Description | Duarte Coello R, Valdés Hernández MC, Zwanenburg JJM, van der Velden M, Kuijf HJ, De Luca A, Bernal Moyano J, Ballerini L, Chappell FM, Brown R, Biessels GJ, Wardlaw JM. On the detectability and accuracy of computational measurements of enlarged perivascular spaces from magnetic resonance images" (under review). 2023;403:110039. University of Edinburgh. Centre for Clinical Brain Sciences. Department of Neuroimaging Sciences. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2023 |
| Provided To Others? | Yes |
| Impact | N/A. |
| URL | https://www.sciencedirect.com/science/article/pii/S0165027023002583 |
| Description | COEN |
| Organisation | German Centre for Neurodegenerative Diseases |
| Department | Institute for Stroke and Dementia Research |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Development of guidelines for contribution of imaging of small vessel disease. |
| Collaborator Contribution | Development of guidelines for contribution of imaging of small vessel disease. |
| Impact | 2 Lancet Neurology papers in 2013 (see publications) Accepted embedded symposiums in the International Stroke Conference (February 2013), European Stroke Conference (May 2013), VasCog (June 2013), and World Stroke Conference (October 2014) Invited lecture (M Dichgans) at 9th World Stroke Congress, Istanbul (see publications) EU Joint Programme - Neurodegenerative Disease Research grant awarded for "Realising the potential of cohort studies to determine the vascular contribution to neurodegeneration", €47,416, 1st Oct 2014 to 31st Mar 2015. J Wardlaw, M Dichgans, F Fazekas, R Schmidt, H Chabriat, C Cordonnier, E Jouvent, MMB Breteler, F Jessen, L Pantoni, GJ Biessels, F-E de Leeuw, MA Ikram, M Vernooij, RJ van Oostenbrugge, C Brayne, IJ Deary, JT O'Brien, PM Matthews, JM Starr, BC Stephan, DJ Werring, E Smith. Lancet Neurology editorial April 2012 (see publications) Methods to evaluate likely underlying mechanisms of SVD are being tested in collaboration between the Austrian Stroke Prevention Study (Fazekas, COEN expert, Gratz) and Edinburgh, including a) evaluation of brain mineral deposition and b) of embolic, atheromatous and intrinsic mechanisms of lacunar stroke in a population study. One paper submitted from collaboration with Fazekas group in Graz. (see publications) Members of the COEN Network are contributing to further secondary analysis of imaging data from the ground-breaking Secondary Prevention of Small Subcortical Stroke (SPS3) trial led by Oscar Benavente (Vancouver, PI, COEN expert), with exchange of fellows between Edinburgh and Vancouver. A research fellow from Maastricht (COEN participant van Oostenbrugge) visited Edinburgh and performed further development of individual SVD features into a total sum score. One paper published (see publications) and one paper in review, publication pending. Collaboration around post-mortem imaging methods for examination of individual vascular features is proceeding between investigators in Lille (COEN expert Cordonnier) and Edinburgh. Neuropathologist (Catherine Humphries) started as Stroke Association Princess Margaret Research Fellow on neuroimaging and neuropathology in SVD, jointly supervised with Colin Smith. Chabriat and colleagues are planning a trial of interventions in a monogenic form of small vessel disease, CADASIL, with input from several COEN partners (Dichgans, Werring, Wardlaw, Benavente). The International Stroke Genetics Consortium has set up an imaging standards subgroup (which includes JM Wardlaw) to improve use of imaging in phenotyping for stroke and dementia gene discovery studies. A publication is accepted in Stroke. Munich collaborators working on various applications. EU Horizon 2020 outline submitted (Dichgans, van Oostenbrugge, Wardlaw. Three groups are working on improved methods for patient stratification and outcome assessment in randomised controlled trials of interventions to prevent progression of small vessel disease and vascular and non-vascular neurodegeneration (Benavente, Chabriat, Wardlaw). Further validation of the derived standard is currently being undertaken by Smith, Wardlaw and Dichgans with Smith leading, including testing the reporting checklist on randomly chosen relevant publications and refining the checklist, expected to report in early 2014. Abstract (E Smith) accepted for International Stoke Conference in February 2015. A multi-centre trial of interventions to prevent small vessel disease progression is being planned in the UK with advice from Benavente and Chabriat. Outline approved by BHF, full submission pending. Application for randomised clinical trial testing two promising agents in a short-term intermediary outcomes trial submitted to Alzheimer's Society. The investment is therefore leading directly to interventions which, if successful, should reduce the impact of the vascular contribution to neurodegeneration. |
| Start Year | 2012 |
| Description | COEN |
| Organisation | Lille University Hospital |
| Department | Department of Neurology |
| Country | France |
| Sector | Hospitals |
| PI Contribution | Development of guidelines for contribution of imaging of small vessel disease. |
| Collaborator Contribution | Development of guidelines for contribution of imaging of small vessel disease. |
| Impact | 2 Lancet Neurology papers in 2013 (see publications) Accepted embedded symposiums in the International Stroke Conference (February 2013), European Stroke Conference (May 2013), VasCog (June 2013), and World Stroke Conference (October 2014) Invited lecture (M Dichgans) at 9th World Stroke Congress, Istanbul (see publications) EU Joint Programme - Neurodegenerative Disease Research grant awarded for "Realising the potential of cohort studies to determine the vascular contribution to neurodegeneration", €47,416, 1st Oct 2014 to 31st Mar 2015. J Wardlaw, M Dichgans, F Fazekas, R Schmidt, H Chabriat, C Cordonnier, E Jouvent, MMB Breteler, F Jessen, L Pantoni, GJ Biessels, F-E de Leeuw, MA Ikram, M Vernooij, RJ van Oostenbrugge, C Brayne, IJ Deary, JT O'Brien, PM Matthews, JM Starr, BC Stephan, DJ Werring, E Smith. Lancet Neurology editorial April 2012 (see publications) Methods to evaluate likely underlying mechanisms of SVD are being tested in collaboration between the Austrian Stroke Prevention Study (Fazekas, COEN expert, Gratz) and Edinburgh, including a) evaluation of brain mineral deposition and b) of embolic, atheromatous and intrinsic mechanisms of lacunar stroke in a population study. One paper submitted from collaboration with Fazekas group in Graz. (see publications) Members of the COEN Network are contributing to further secondary analysis of imaging data from the ground-breaking Secondary Prevention of Small Subcortical Stroke (SPS3) trial led by Oscar Benavente (Vancouver, PI, COEN expert), with exchange of fellows between Edinburgh and Vancouver. A research fellow from Maastricht (COEN participant van Oostenbrugge) visited Edinburgh and performed further development of individual SVD features into a total sum score. One paper published (see publications) and one paper in review, publication pending. Collaboration around post-mortem imaging methods for examination of individual vascular features is proceeding between investigators in Lille (COEN expert Cordonnier) and Edinburgh. Neuropathologist (Catherine Humphries) started as Stroke Association Princess Margaret Research Fellow on neuroimaging and neuropathology in SVD, jointly supervised with Colin Smith. Chabriat and colleagues are planning a trial of interventions in a monogenic form of small vessel disease, CADASIL, with input from several COEN partners (Dichgans, Werring, Wardlaw, Benavente). The International Stroke Genetics Consortium has set up an imaging standards subgroup (which includes JM Wardlaw) to improve use of imaging in phenotyping for stroke and dementia gene discovery studies. A publication is accepted in Stroke. Munich collaborators working on various applications. EU Horizon 2020 outline submitted (Dichgans, van Oostenbrugge, Wardlaw. Three groups are working on improved methods for patient stratification and outcome assessment in randomised controlled trials of interventions to prevent progression of small vessel disease and vascular and non-vascular neurodegeneration (Benavente, Chabriat, Wardlaw). Further validation of the derived standard is currently being undertaken by Smith, Wardlaw and Dichgans with Smith leading, including testing the reporting checklist on randomly chosen relevant publications and refining the checklist, expected to report in early 2014. Abstract (E Smith) accepted for International Stoke Conference in February 2015. A multi-centre trial of interventions to prevent small vessel disease progression is being planned in the UK with advice from Benavente and Chabriat. Outline approved by BHF, full submission pending. Application for randomised clinical trial testing two promising agents in a short-term intermediary outcomes trial submitted to Alzheimer's Society. The investment is therefore leading directly to interventions which, if successful, should reduce the impact of the vascular contribution to neurodegeneration. |
| Start Year | 2012 |
| Description | COEN |
| Organisation | Medical University of Graz |
| Department | Department of Neurology |
| Country | Austria |
| Sector | Academic/University |
| PI Contribution | Development of guidelines for contribution of imaging of small vessel disease. |
| Collaborator Contribution | Development of guidelines for contribution of imaging of small vessel disease. |
| Impact | 2 Lancet Neurology papers in 2013 (see publications) Accepted embedded symposiums in the International Stroke Conference (February 2013), European Stroke Conference (May 2013), VasCog (June 2013), and World Stroke Conference (October 2014) Invited lecture (M Dichgans) at 9th World Stroke Congress, Istanbul (see publications) EU Joint Programme - Neurodegenerative Disease Research grant awarded for "Realising the potential of cohort studies to determine the vascular contribution to neurodegeneration", €47,416, 1st Oct 2014 to 31st Mar 2015. J Wardlaw, M Dichgans, F Fazekas, R Schmidt, H Chabriat, C Cordonnier, E Jouvent, MMB Breteler, F Jessen, L Pantoni, GJ Biessels, F-E de Leeuw, MA Ikram, M Vernooij, RJ van Oostenbrugge, C Brayne, IJ Deary, JT O'Brien, PM Matthews, JM Starr, BC Stephan, DJ Werring, E Smith. Lancet Neurology editorial April 2012 (see publications) Methods to evaluate likely underlying mechanisms of SVD are being tested in collaboration between the Austrian Stroke Prevention Study (Fazekas, COEN expert, Gratz) and Edinburgh, including a) evaluation of brain mineral deposition and b) of embolic, atheromatous and intrinsic mechanisms of lacunar stroke in a population study. One paper submitted from collaboration with Fazekas group in Graz. (see publications) Members of the COEN Network are contributing to further secondary analysis of imaging data from the ground-breaking Secondary Prevention of Small Subcortical Stroke (SPS3) trial led by Oscar Benavente (Vancouver, PI, COEN expert), with exchange of fellows between Edinburgh and Vancouver. A research fellow from Maastricht (COEN participant van Oostenbrugge) visited Edinburgh and performed further development of individual SVD features into a total sum score. One paper published (see publications) and one paper in review, publication pending. Collaboration around post-mortem imaging methods for examination of individual vascular features is proceeding between investigators in Lille (COEN expert Cordonnier) and Edinburgh. Neuropathologist (Catherine Humphries) started as Stroke Association Princess Margaret Research Fellow on neuroimaging and neuropathology in SVD, jointly supervised with Colin Smith. Chabriat and colleagues are planning a trial of interventions in a monogenic form of small vessel disease, CADASIL, with input from several COEN partners (Dichgans, Werring, Wardlaw, Benavente). The International Stroke Genetics Consortium has set up an imaging standards subgroup (which includes JM Wardlaw) to improve use of imaging in phenotyping for stroke and dementia gene discovery studies. A publication is accepted in Stroke. Munich collaborators working on various applications. EU Horizon 2020 outline submitted (Dichgans, van Oostenbrugge, Wardlaw. Three groups are working on improved methods for patient stratification and outcome assessment in randomised controlled trials of interventions to prevent progression of small vessel disease and vascular and non-vascular neurodegeneration (Benavente, Chabriat, Wardlaw). Further validation of the derived standard is currently being undertaken by Smith, Wardlaw and Dichgans with Smith leading, including testing the reporting checklist on randomly chosen relevant publications and refining the checklist, expected to report in early 2014. Abstract (E Smith) accepted for International Stoke Conference in February 2015. A multi-centre trial of interventions to prevent small vessel disease progression is being planned in the UK with advice from Benavente and Chabriat. Outline approved by BHF, full submission pending. Application for randomised clinical trial testing two promising agents in a short-term intermediary outcomes trial submitted to Alzheimer's Society. The investment is therefore leading directly to interventions which, if successful, should reduce the impact of the vascular contribution to neurodegeneration. |
| Start Year | 2012 |
| Description | COEN |
| Organisation | University of Calgary |
| Department | Department of Clinical Neurosciences |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Development of guidelines for contribution of imaging of small vessel disease. |
| Collaborator Contribution | Development of guidelines for contribution of imaging of small vessel disease. |
| Impact | 2 Lancet Neurology papers in 2013 (see publications) Accepted embedded symposiums in the International Stroke Conference (February 2013), European Stroke Conference (May 2013), VasCog (June 2013), and World Stroke Conference (October 2014) Invited lecture (M Dichgans) at 9th World Stroke Congress, Istanbul (see publications) EU Joint Programme - Neurodegenerative Disease Research grant awarded for "Realising the potential of cohort studies to determine the vascular contribution to neurodegeneration", €47,416, 1st Oct 2014 to 31st Mar 2015. J Wardlaw, M Dichgans, F Fazekas, R Schmidt, H Chabriat, C Cordonnier, E Jouvent, MMB Breteler, F Jessen, L Pantoni, GJ Biessels, F-E de Leeuw, MA Ikram, M Vernooij, RJ van Oostenbrugge, C Brayne, IJ Deary, JT O'Brien, PM Matthews, JM Starr, BC Stephan, DJ Werring, E Smith. Lancet Neurology editorial April 2012 (see publications) Methods to evaluate likely underlying mechanisms of SVD are being tested in collaboration between the Austrian Stroke Prevention Study (Fazekas, COEN expert, Gratz) and Edinburgh, including a) evaluation of brain mineral deposition and b) of embolic, atheromatous and intrinsic mechanisms of lacunar stroke in a population study. One paper submitted from collaboration with Fazekas group in Graz. (see publications) Members of the COEN Network are contributing to further secondary analysis of imaging data from the ground-breaking Secondary Prevention of Small Subcortical Stroke (SPS3) trial led by Oscar Benavente (Vancouver, PI, COEN expert), with exchange of fellows between Edinburgh and Vancouver. A research fellow from Maastricht (COEN participant van Oostenbrugge) visited Edinburgh and performed further development of individual SVD features into a total sum score. One paper published (see publications) and one paper in review, publication pending. Collaboration around post-mortem imaging methods for examination of individual vascular features is proceeding between investigators in Lille (COEN expert Cordonnier) and Edinburgh. Neuropathologist (Catherine Humphries) started as Stroke Association Princess Margaret Research Fellow on neuroimaging and neuropathology in SVD, jointly supervised with Colin Smith. Chabriat and colleagues are planning a trial of interventions in a monogenic form of small vessel disease, CADASIL, with input from several COEN partners (Dichgans, Werring, Wardlaw, Benavente). The International Stroke Genetics Consortium has set up an imaging standards subgroup (which includes JM Wardlaw) to improve use of imaging in phenotyping for stroke and dementia gene discovery studies. A publication is accepted in Stroke. Munich collaborators working on various applications. EU Horizon 2020 outline submitted (Dichgans, van Oostenbrugge, Wardlaw. Three groups are working on improved methods for patient stratification and outcome assessment in randomised controlled trials of interventions to prevent progression of small vessel disease and vascular and non-vascular neurodegeneration (Benavente, Chabriat, Wardlaw). Further validation of the derived standard is currently being undertaken by Smith, Wardlaw and Dichgans with Smith leading, including testing the reporting checklist on randomly chosen relevant publications and refining the checklist, expected to report in early 2014. Abstract (E Smith) accepted for International Stoke Conference in February 2015. A multi-centre trial of interventions to prevent small vessel disease progression is being planned in the UK with advice from Benavente and Chabriat. Outline approved by BHF, full submission pending. Application for randomised clinical trial testing two promising agents in a short-term intermediary outcomes trial submitted to Alzheimer's Society. The investment is therefore leading directly to interventions which, if successful, should reduce the impact of the vascular contribution to neurodegeneration. |
| Start Year | 2012 |
| Description | COEN |
| Organisation | University of Sydney |
| Department | Westmead Clinical School |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Development of guidelines for contribution of imaging of small vessel disease. |
| Collaborator Contribution | Development of guidelines for contribution of imaging of small vessel disease. |
| Impact | 2 Lancet Neurology papers in 2013 (see publications) Accepted embedded symposiums in the International Stroke Conference (February 2013), European Stroke Conference (May 2013), VasCog (June 2013), and World Stroke Conference (October 2014) Invited lecture (M Dichgans) at 9th World Stroke Congress, Istanbul (see publications) EU Joint Programme - Neurodegenerative Disease Research grant awarded for "Realising the potential of cohort studies to determine the vascular contribution to neurodegeneration", €47,416, 1st Oct 2014 to 31st Mar 2015. J Wardlaw, M Dichgans, F Fazekas, R Schmidt, H Chabriat, C Cordonnier, E Jouvent, MMB Breteler, F Jessen, L Pantoni, GJ Biessels, F-E de Leeuw, MA Ikram, M Vernooij, RJ van Oostenbrugge, C Brayne, IJ Deary, JT O'Brien, PM Matthews, JM Starr, BC Stephan, DJ Werring, E Smith. Lancet Neurology editorial April 2012 (see publications) Methods to evaluate likely underlying mechanisms of SVD are being tested in collaboration between the Austrian Stroke Prevention Study (Fazekas, COEN expert, Gratz) and Edinburgh, including a) evaluation of brain mineral deposition and b) of embolic, atheromatous and intrinsic mechanisms of lacunar stroke in a population study. One paper submitted from collaboration with Fazekas group in Graz. (see publications) Members of the COEN Network are contributing to further secondary analysis of imaging data from the ground-breaking Secondary Prevention of Small Subcortical Stroke (SPS3) trial led by Oscar Benavente (Vancouver, PI, COEN expert), with exchange of fellows between Edinburgh and Vancouver. A research fellow from Maastricht (COEN participant van Oostenbrugge) visited Edinburgh and performed further development of individual SVD features into a total sum score. One paper published (see publications) and one paper in review, publication pending. Collaboration around post-mortem imaging methods for examination of individual vascular features is proceeding between investigators in Lille (COEN expert Cordonnier) and Edinburgh. Neuropathologist (Catherine Humphries) started as Stroke Association Princess Margaret Research Fellow on neuroimaging and neuropathology in SVD, jointly supervised with Colin Smith. Chabriat and colleagues are planning a trial of interventions in a monogenic form of small vessel disease, CADASIL, with input from several COEN partners (Dichgans, Werring, Wardlaw, Benavente). The International Stroke Genetics Consortium has set up an imaging standards subgroup (which includes JM Wardlaw) to improve use of imaging in phenotyping for stroke and dementia gene discovery studies. A publication is accepted in Stroke. Munich collaborators working on various applications. EU Horizon 2020 outline submitted (Dichgans, van Oostenbrugge, Wardlaw. Three groups are working on improved methods for patient stratification and outcome assessment in randomised controlled trials of interventions to prevent progression of small vessel disease and vascular and non-vascular neurodegeneration (Benavente, Chabriat, Wardlaw). Further validation of the derived standard is currently being undertaken by Smith, Wardlaw and Dichgans with Smith leading, including testing the reporting checklist on randomly chosen relevant publications and refining the checklist, expected to report in early 2014. Abstract (E Smith) accepted for International Stoke Conference in February 2015. A multi-centre trial of interventions to prevent small vessel disease progression is being planned in the UK with advice from Benavente and Chabriat. Outline approved by BHF, full submission pending. Application for randomised clinical trial testing two promising agents in a short-term intermediary outcomes trial submitted to Alzheimer's Society. The investment is therefore leading directly to interventions which, if successful, should reduce the impact of the vascular contribution to neurodegeneration. |
| Start Year | 2012 |
| Description | COEN |
| Organisation | Utrecht University |
| Department | Rudolf Magnus Institute |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Development of guidelines for contribution of imaging of small vessel disease. |
| Collaborator Contribution | Development of guidelines for contribution of imaging of small vessel disease. |
| Impact | 2 Lancet Neurology papers in 2013 (see publications) Accepted embedded symposiums in the International Stroke Conference (February 2013), European Stroke Conference (May 2013), VasCog (June 2013), and World Stroke Conference (October 2014) Invited lecture (M Dichgans) at 9th World Stroke Congress, Istanbul (see publications) EU Joint Programme - Neurodegenerative Disease Research grant awarded for "Realising the potential of cohort studies to determine the vascular contribution to neurodegeneration", €47,416, 1st Oct 2014 to 31st Mar 2015. J Wardlaw, M Dichgans, F Fazekas, R Schmidt, H Chabriat, C Cordonnier, E Jouvent, MMB Breteler, F Jessen, L Pantoni, GJ Biessels, F-E de Leeuw, MA Ikram, M Vernooij, RJ van Oostenbrugge, C Brayne, IJ Deary, JT O'Brien, PM Matthews, JM Starr, BC Stephan, DJ Werring, E Smith. Lancet Neurology editorial April 2012 (see publications) Methods to evaluate likely underlying mechanisms of SVD are being tested in collaboration between the Austrian Stroke Prevention Study (Fazekas, COEN expert, Gratz) and Edinburgh, including a) evaluation of brain mineral deposition and b) of embolic, atheromatous and intrinsic mechanisms of lacunar stroke in a population study. One paper submitted from collaboration with Fazekas group in Graz. (see publications) Members of the COEN Network are contributing to further secondary analysis of imaging data from the ground-breaking Secondary Prevention of Small Subcortical Stroke (SPS3) trial led by Oscar Benavente (Vancouver, PI, COEN expert), with exchange of fellows between Edinburgh and Vancouver. A research fellow from Maastricht (COEN participant van Oostenbrugge) visited Edinburgh and performed further development of individual SVD features into a total sum score. One paper published (see publications) and one paper in review, publication pending. Collaboration around post-mortem imaging methods for examination of individual vascular features is proceeding between investigators in Lille (COEN expert Cordonnier) and Edinburgh. Neuropathologist (Catherine Humphries) started as Stroke Association Princess Margaret Research Fellow on neuroimaging and neuropathology in SVD, jointly supervised with Colin Smith. Chabriat and colleagues are planning a trial of interventions in a monogenic form of small vessel disease, CADASIL, with input from several COEN partners (Dichgans, Werring, Wardlaw, Benavente). The International Stroke Genetics Consortium has set up an imaging standards subgroup (which includes JM Wardlaw) to improve use of imaging in phenotyping for stroke and dementia gene discovery studies. A publication is accepted in Stroke. Munich collaborators working on various applications. EU Horizon 2020 outline submitted (Dichgans, van Oostenbrugge, Wardlaw. Three groups are working on improved methods for patient stratification and outcome assessment in randomised controlled trials of interventions to prevent progression of small vessel disease and vascular and non-vascular neurodegeneration (Benavente, Chabriat, Wardlaw). Further validation of the derived standard is currently being undertaken by Smith, Wardlaw and Dichgans with Smith leading, including testing the reporting checklist on randomly chosen relevant publications and refining the checklist, expected to report in early 2014. Abstract (E Smith) accepted for International Stoke Conference in February 2015. A multi-centre trial of interventions to prevent small vessel disease progression is being planned in the UK with advice from Benavente and Chabriat. Outline approved by BHF, full submission pending. Application for randomised clinical trial testing two promising agents in a short-term intermediary outcomes trial submitted to Alzheimer's Society. The investment is therefore leading directly to interventions which, if successful, should reduce the impact of the vascular contribution to neurodegeneration. |
| Start Year | 2012 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Aarhus University |
| Country | Denmark |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Alberta Health Services |
| Country | Canada |
| Sector | Public |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Boston University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Chinese University of Hong Kong |
| Country | Hong Kong |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Erasmus MC |
| Country | Netherlands |
| Sector | Hospitals |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Imperial College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Lariboisière Hospital |
| Country | France |
| Sector | Hospitals |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Leiden University Medical Center |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Ludwig Maximilian University of Munich (LMU Munich) |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Maastricht University Medical Center+ |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Massachusetts General Hospital |
| Country | United States |
| Sector | Hospitals |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | McGill University |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | McMaster University |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Medical University of Graz |
| Country | Austria |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | National Institutes of Health (NIH) |
| Country | United States |
| Sector | Public |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | National University of Singapore |
| Country | Singapore |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Radboud University Nijmegen Medical Center |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | The Otto-von-Guericke University Magdeburg |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University College London |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University Hospital Carl Gustav Carus Dresden |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University Medical Center Rotterdam |
| Country | Netherlands |
| Sector | Hospitals |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University Medical Center Utrecht (UMC) |
| Country | Netherlands |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University of Bonn |
| Country | Germany |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University of Bordeaux |
| Country | France |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University of Calgary |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University of California, Davis |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University of Florence |
| Country | Italy |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University of Iceland |
| Country | Iceland |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University of Laval |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University of Leeds |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University of New South Wales |
| Country | Australia |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | University of Toronto |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | JPND "HARmoNising Brain Imaging Methods for VaScular Contributions to Neurodegeneration (HARNESS)" |
| Organisation | Western University |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | Prof Joanna Wardlaw was one of the main researchers on the funding application and is currently helping to coordinate the collaboration. |
| Collaborator Contribution | The objective of HARNESS is to develop standardized methods for using brain scans to diagnose vascular dementia. Over a series of teleconferences and meetings were held to: 1) plan an internet-based repository for instructions on how to do magnetic resonance imaging (MRI) scans to detect vascular dementia, 2) host examples of scans with different kinds of blood vessel diseases, so radiologists and researchers can learn what they look like and practice measuring them, 3) provide instructions for how to test the reliability of MRI scanner measurements, and 4) review new ways to do scans to diagnose vascular dementia. |
| Impact | Too early to say |
| Start Year | 2017 |
| Description | "Cerebral small vessel disease" - Invited lecture. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | African Stroke Organisation 3rd Annual Conference. Ibadan, Nigeria, 03 November 2023. |
| Year(s) Of Engagement Activity | 2023 |
| Description | "Cerebral small vessel disease: advances in mechanisms and treatment from neuroimaging" - Invited lecture. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Professional Practitioners |
| Results and Impact | BSNR Annual Scientific Meeting. Edinburgh, United Kingdom, 27 September 2023. |
| Year(s) Of Engagement Activity | 2023 |
| Description | "Cerebral small vessel disease: mechanisms, prevention and treatment" - Invited lecture. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The 9th Professor Sir John Walton Lecture, Association of British Neurologists Annual Meeting. London, UK, 08 November 2023. |
| Year(s) Of Engagement Activity | 2023 |
| Description | "Clinical VCI" Plenary I Keynote, VasCog 2021 Virtual 11th International Conference of the VasCog Society, 8th September 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | "Evolving insights in cerebral small vessel disease" - Invited lecture. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Lund Neuroscience Day 2023 Segerfalk Foundation. Lund, Sweden, 04 May 2023. |
| Year(s) Of Engagement Activity | 2023 |
| Description | "Lacunar stroke and small vessel disease are not just 'small strokes': implications for treatment" - Invited lecture. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Eppendorfer Neurologisches Kolloquium. Hamburg, Germany, 07 February 2024. |
| Year(s) Of Engagement Activity | 2024 |
| Description | "Neurology and Neuroradiology Collaborations to Detect cSVD" 13th World Stroke Organisation Conference 2021, 29 October 2021, virtual. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | "New developments in cerebral small vessel diseases" Keynote: 56th Annual Meeting of the German Society of Neuroradiology - virtual meeting 8th October 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | "New neuroimaging standards for cerebral SVD STRIVE-2" - Invited lecture. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Korean Stroke Society symposium 2023. Seoul, Korea, 23 September 2023. |
| Year(s) Of Engagement Activity | 2023 |
| Description | "Pharmacological and lifestyle interventions" - Invited lectures. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | World Stroke Organisation - World Stroke Academy. Virtual webinar, 16 November 2023. |
| Year(s) Of Engagement Activity | 2023 |
| Description | "Prevention and treatment of cerebral small vessel disease" - Invited lectures. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | World Stroke Organisation Webinar. 16 November 2023. |
| Year(s) Of Engagement Activity | 2023 |
| Description | "STRIVE-2 high standards" - Invited lecture. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | European Sroke Organisation - 7th European Stroke Science Conference. Garmisch-Partenkirchen, Germany, 01 December 2023. |
| Year(s) Of Engagement Activity | 2023 |
| Description | "Stroke, small vessel disease and dementia - recent studies" - Invited lecture. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | The 2024 National Dementias Conference. London, UK, 09 February 2024. |
| Year(s) Of Engagement Activity | 2024 |
| Description | "Therapeutic Approaches for Hypertensive Brain Small Vessel Disease" - Invited lecture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | American Heart Association International Stroke Conference 2023. Dallas, Texas, USA, 09 February 2023. |
| Year(s) Of Engagement Activity | 2023 |
| Description | "Updated STRIVE-2 criteria for small vessel disease" - Invited lectures. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | NHS Scotland National Stroke meetings. Virtual webinar, 22 November 2023. |
| Year(s) Of Engagement Activity | 2023 |
| Description | 'New Insights into clinical features of SVD' 20th Congress of the Chinese Cerebrovascular Diseases (CCCD2020) Chinese Stroke Society |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | This was a virtual conference |
| Year(s) Of Engagement Activity | 2020 |
| Description | 'Recent advances in cerebral small vessel disease', Irish Heart Foundation Council on Stroke 2021, 16 April 2021, Dublin/Virtual |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | 'Relevance of cerebral SVD' XXI joint meeting of Mexican Stroke Association (AMEVASC) and the Ibero-American Stroke Association, (SIECV), 2nd Oct 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | 'Small vessel disease: recent clinical, mechanistic and potential therapeutic insights.' Catalan Society of Neurology Cerebrovascular Diseases Group. 10 March 2021, Barcelona |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | 'Treatment approaches to cerebral small vessel disease' European Stroke Organisation and World Stroke Organisation Conference 2020 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Virtual meeting |
| Year(s) Of Engagement Activity | 2020 |
| Description | 'Vascular contributions to dementia' Imperial College Neuroscience and Dementia Research Institute Brain Meeting, January 7th 2020, London |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | 'What does the scientific evidence mean to the public?' World Stroke Organisation Stroke Prevention Webinar: Prevention of Stroke and Dementia, Virtual, and online, 17 Aug 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | 11° Congresso Português do AVC, talk by Prof Joanna Wardlaw: "Imaging studies in vascular cognitive impairment" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw was invited to give a talk at the 11° Congresso Português do AVC (11th Portuguese Stroke Congress) in Porto, Portugal, on 2 February 2016; the talk was "Imaging studies in vascular cognitive impairment". |
| Year(s) Of Engagement Activity | 2017 |
| Description | Alzheimer's Research UK Manchester and NorthWest Network Centre Science Day, talk by Prof Joanna Wardlaw: "Vascular disease and neurodegeneration - structural and functional insights from neuroimaging in humans" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw was invited to give at talk at the Alzheimer's Research UK Manchester and NorthWest Network Centre Science Day on 18 May 2016, in Manchester, UK. The talk was entitled: "Vascular disease and neurodegeneration - structural and functional insights from neuroimaging in humans". |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.alzheimersresearchuk.org/research-projects/alzheimers-research-uk-manchester-north-west-n... |
| Description | Daily Mail press release, What the experts do to stave off dementia: After exciting new drug breakthrough, our guide to the precautions you can take to lessen your chances of the condition. 14 June 2021 What the experts do to stave off dementia | Daily Mail Online |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | media |
| Year(s) Of Engagement Activity | 2021 |
| Description | Dementia imaging, past landmarks and future prospects', Keynote, RiiSE21 (Radiological Imaging and Intervention Symposium Edinburgh 2021) 10 April 2021 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Virtual meeting |
| Year(s) Of Engagement Activity | 2021 |
| Description | Invited lecture - European Congress of Radiology 2022, 02 March 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited lecture by Professor Joanna Wardlaw - "White spots in the white matter" European Congress of Radiology 2022, 02 March 2022,Virtual. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited lecture - German Center for Neurodegenerative Diseases (DZNE), Magdeburg, 04 April 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited lecture by Professor Joanna Wardlaw - "SVD - recent insights into mechanisms, lesions and symptoms" German Center for Neurodegenerative Diseases (DZNE), Magdeburg, 04 April 2022, Virtual. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited lecture - Imperial College and Charing Cross Hospital Neurosciences Clinical-Scientific Meetings 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited lecture "Small vessel disease: recent clinical insights and therapeutic implications" Imperial College and Charing Cross Hospital Neurosciences Clinical-Scientific Meetings, 14th January 2022 |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited lecture Univeristy, Nijmegen. 23 February 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited lecture by Professor Joanna Wardlaw - "Recent observations in cerebral small vessel disease and clinical implications" Radboud Univeristy, Nijmegen. 23 February 2022,virtual. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited talk - British and Irish Hypertension Society - Annual Scientific Meeting, Barbican, York, 12-14 September 2022. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk by Professor Joanna Wardlaw - "BP in cerebral small vessel disease and vascular dementia" British and Irish Hypertension Society - Annual Scientific Meeting, Barbican, York, 12-14 September 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited talk - European Stroke Organisation Conference 2022, Lyon, France, 3-6 May 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | "Problems with waste clearance from the human brain: what to look out for" European Stroke Organisation Conference 2022, Lyon, France, 3-6 May 2022 |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited talk - Gdansk Dept of Neurology Festival, 19 May 2022 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited lecture by Professor Wardlaw - "Major Developments in Clinical Neurology" Gdansk Dept of Neurology Festival, 19 May 2022,Virtual. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited talk - The 2022 Tianfu Stroke Conference, Chengdu, China |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | talk by Professor Wardlaw - "Small vessel Disease mechanisms and clinical features: new findings in the last year" The 2022 Tianfu Stroke Conference, Chengdu, China, 21-22 October 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited talk - The FENS Forum 2022,Paris, France, 9-13 July 2022. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited lecture by Professor Wardlaw - "Mechanisims of cerebral small vessel dysfunction in vascular cognitive impairment and dementia" The FENS Forum 2022,Paris, France, 9-13 July 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited talk - Veterinary Diagnostic Imaging annual meeting |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | "Imaging for human dementia" European College and the European Association in Veterinary Diagnostic Imaging annual meeting, Edinburgh, Scotland, 15 September 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Invited talk at UK Stroke Forum.Liverpool, England, 29 November-01 December 2022. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Talk by Professor Wardlaw - "Can we prevent progression of cerebral small vessel disease" UK Stroke Forum.Liverpool, England, 29 November-01 December 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Keynote lecture - The Inaugural SVD@TheJeff Symposium, University of Manchester |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited keynote lecture by Professor Joanna Wardlaw, "Small vessel disease mechanisms, progression and potential therapeutics". The Inaugural SVD@TheJeff Symposium, University of Manchester. 19 January 2022. |
| Year(s) Of Engagement Activity | 2022 |
| Description | Microvascular dysfunction in cerebral small vessel disease: implications for therapeutic approaches, 71st Annual British Microcirculation and Vascular Biology Society Conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | virtual seminar |
| Year(s) Of Engagement Activity | 2017,2021 |
| Description | Prof Joanna Wardlaw feature in Health Matters magazine |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | A feature in Health Matters magazine, Winter 2018-2019 issue, P 24-25. Wardlaw, JM. "MRI scans of the brain". |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Joanna Wardlaw keynote talk "Recent advances in small vessel disease", Chengdu, China. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk "Recent advances in small vessel disease" at the 2019 Tianfu International Stroke Conference, Keynote, 1st June 2019, Chengdu, China. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Joanna Wardlaw lecture "Brain Health: a small matter of the blood vessels" in Edinburgh, UK. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Edinburgh Neuroscience Public Christmas Lecture 2018 |
| Year(s) Of Engagement Activity | 2018 |
| Description | Prof Joanna Wardlaw talk "CMB Definition and Prevalence" and 'Impact of Cerebral Microbleeds (CMB) on Stroke Management', Milan, Italy. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk "CMB Definition and Prevalence" and 'Impact of Cerebral Microbleeds (CMB) on Stroke Management' teaching course, 5th European Stroke Organisation Conference (ESOC 2019), 23rd May 2019, Milan, Italy. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Joanna Wardlaw talk "Cerebral small vessel disease is a relapsing and remitting neurodegenerative disorder" in Birmingham, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk "Cerebral small vessel disease is a relapsing and remitting neurodegenerative disorder" on the 4th Oct 2019, MRC UK Dementia Research Institute Annual Scientific Meeting (Connectome), in Birmingham, UK |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Joanna Wardlaw talk "Cerebral small vessel disease: novel targets for prevention" in Berlin, Germany. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Presentation on 'Cerebral small vessel disease: novel targets for prevention' at the 'Dementia Prevention by Stroke Prevention' World Health Summit Satellite Symposium on October 13, 2018 in Berlin. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Prof Joanna Wardlaw talk "Cerebral vascular dysfunctions detected in human small vessel disease and implications for preclinical studies" in Burlington, VT, USA. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw gave a talk on "Cerebral vascular dysfunctions detected in human small vessel disease and implications for preclinical studies" at The University of Vermont, Burlington, VT on Monday 22, 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Prof Joanna Wardlaw talk "Does ischaemia play a role in SVD lesion development?" in Montreal, Canada. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw gave a talk on "Does ischaemia play a role in SVD lesion development?" at the 11th World Stroke Congress in Montreal, Canada on October 19, 2018. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Prof Joanna Wardlaw talk "Mechanisms of small vessel disease" in Seattle, WA, USA |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw gave at talk called "Mechanisms of small vessel disease" to the Neuroscience Department in Seattle, WA, USA, on 1 June 2017. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Prof Joanna Wardlaw talk "Recent advances in small vessel disease" in Calgary, Canada |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw gave at talk called "Recent advances in small vessel disease" to the Stroke Research & Neuroscience Department in Calgary, Canada on 15 June 2017. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Prof Joanna Wardlaw talk "Vascular contributions to dementia" Imperial College Neuroscience and Dementia Research Institute Brain Meeting, January 7th 2021, London (virtual) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk "Vascular contributions to dementia" Imperial College Neuroscience and Dementia Research Institute Brain Meeting, January 7th 2021, London (virtual) |
| Year(s) Of Engagement Activity | 2021 |
| Description | Prof Joanna Wardlaw talk "What makes a good paper and how to prepare it? Suggestions based on my person experience",Beijing, China |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk "What makes a good paper and how to prepare it? Suggestions based on my person experience", at the Tiantan International Stroke Conference 2019, 28 June 2019, Beijing, China |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Joanna Wardlaw talk "Where next for stroke research?" in Edinburgh, UK. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk "Where next for stroke research?"at the 6th Edinburgh Stroke Winter School, 19th February 2019, Edinburgh, UK. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Joanna Wardlaw talk ''Imaging - where we are and where we are headed'', Royal College of Physicians, Edinburgh, UK |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk ''Imaging - where we are and where we are headed'' at the Diagnostic Medicine - from stethoscope to artificial intelligence 2019, 19 September 2019, Royal College of Physicians, Edinburgh, UK |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Joanna Wardlaw talk 'New insights into clinical features of SVD' 20th Congress of the Chinese Cerebrovascular Diseases (CCCD2020) Chinese Stroke Society, 4 November 2020(virtua!) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk 'New insights into clinical features of SVD' 20th Congress of the Chinese Cerebrovascular Diseases (CCCD2020) Chinese Stroke Society, 4 November 2020(virtua!) |
| Year(s) Of Engagement Activity | 2020 |
| Description | Prof Joanna Wardlaw talk 'Why is one small blood vessel such a giant problem for mankind?', 2nd Lenstra Lecture, Lugano, Switzerland |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk 'Why is one small blood vessel such a giant problem for mankind?' at the 2nd Lenstra Lecture 2019, Philantrhopic Endowed Lecture, Swiss Italian Centre for Neuroscience, in Lugano, Switzerland, 1 October 2019. |
| Year(s) Of Engagement Activity | 2019 |
| Description | Prof Joanna Wardlaw talk titled 'Advanced neuroimaging in CSVD', Chinese Stroke Association, Tiantan International Summit Symposium on Cerebral Small Vessel Diseases 2020 (SSVD-TSVD2020), Nov 20-21, 2020, Beijing, virtual. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw talk 'Advanced neuroimaging in CSVD', Chinese Stroke Association, Tiantan International Summit Symposium on Cerebral Small Vessel Diseases 2020 (SSVD-TSVD2020), Nov 20-21, 2020, Beijing, virtual. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Professor Joanna Wardlaw talk "Where next for stroke research?" 7th ESO Edinburgh Stroke Research Workshop, 26th February 2020, Edinburgh, UK. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Joanna Wardlaw talk "Where next for stroke research?" 7th ESO Edinburgh Stroke Research Workshop, 26th February 2020, Edinburgh, UK. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Professor Joanna Wardlaw talk 'Change the system'- tailoring leadership to women, European Stroke Organisation Women Initiative for Stroke in Europe Leadership workshop 2020, November 9th 2020 Vienna virtual |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Joanna Wardlaw talk 'Change the system'- tailoring leadership to women, European Stroke Organisation Women Initiative for Stroke in Europe Leadership workshop 2020, November 9th 2020 Vienna virtual |
| Year(s) Of Engagement Activity | 2020 |
| Description | Professor Joanna Wardlaw talk 'Research in Vascular Dementia 2019-20'. Scottish Dementia Research Consortium (SDRC), Research in Vascular Dementia 2019-20, 7th September 2020, Virtual Session. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Joanna Wardlaw talk 'Research in Vascular Dementia 2019-20'. Scottish Dementia Research Consortium (SDRC), Research in Vascular Dementia 2019-20, 7th September 2020, Virtual Session. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Professor Joanna Wardlaw talk 'Small Vessel Disease: Clinical, imaging and mechanistic insights.' Yale School of Medicine Grand Round 16th October 2020 (undertaken virtually, including meetings with residents and senior researchers) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Joanna Wardlaw talk 'Small Vessel Disease: Clinical, imaging and mechanistic insights.' Yale School of Medicine Grand Round 16th October 2020 (undertaken virtually, including meetings with residents and senior researchers) |
| Year(s) Of Engagement Activity | 2020 |
| Description | Professor Joanna Wardlaw talk 'Treatment approaches to cerebral small vessel disease", European Stroke Organisation and World Stroke Organisation Conference 2020, November 8th 2020, Vienna, virtual. |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Professor Joanna Wardlaw talk 'Treatment approaches to cerebral small vessel disease", European Stroke Organisation and World Stroke Organisation Conference 2020, November 8th 2020, Vienna, virtual. |
| Year(s) Of Engagement Activity | 2020 |
| Description | Recognized as an Expertscape World Expert in the Blood-Brain Barrier. Expertscape's PubMed-based algorithms placed Joanna in the top 0.1% of scholars writing about the Blood-Brain Barrier over the past 10years |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | https://twitter.com/Daily_Experts/status/1417385315556335616 |
| Year(s) Of Engagement Activity | 2021 |
| Description | Royal College of Physicians 'Women in medicine: a celebration' project |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Royal College of Physicians (RCP)'s 'Women in medicine: a celebration' project is a free exhibition of specially commissioned photographic portraits to honour contemporary and historical women in medicine. The project showcased a number of today's leading female clinicians and the women from the history of medicine who have inspired them. Prof Joanna Wardlaw is featured in the project alongside someone who inspired her, Marie Sklodowska Curie: https://www.rcplondon.ac.uk/projects/outputs/women-medicine-joanna-wardlaw-and-marie-curie |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.rcplondon.ac.uk/events/women-medicine-celebration |
| Description | Royal College of Radiologists Research Day, talk by Prof Joanna Wardlaw: "A day in the life of an academic radiologist" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw was invited to give at talk at the Royal College of Radiologists Research Day on 15 November 2016 in London, UK. The talk was entitled, "A day in the life of an academic radiologist". |
| Year(s) Of Engagement Activity | 2016 |
| Description | SVD Research LinkedIn |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | SVD Research LinkedIn social media channel promoting work of the University of Edinburgh SVD Research groups, including publications, awards, press releases, recent vacancies and other associated activities, aiming to build an international network of professionals specialising in the SVD Research and promote the research to funding bodies, policy makers and industry professionals. |
| Year(s) Of Engagement Activity | 2021 |
| URL | https://uk.linkedin.com/in/svd-research-5aaa27199 |
| Description | Scottish Church Theology Society, talk by Prof Joanna Wardlaw: "The challenges of modern biology - the brain" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Prof Joanna Wardlaw was invited to give a talk at The Scottish Church Theology Society on 12 January 2016 in Peebles, UK. The talk was entitled: "The Challenge of Modern Biology - The Brain". |
| Year(s) Of Engagement Activity | 2016 |
| Description | Scottish Radiological Society Annual General Meeting, talk by Prof Joanna Wardlaw: "The Role of Acute Imaging in Stroke" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw was invited to give at talk at the Scottish Radiological Society's Annual General Meeting on 11 November 2016 in Dundee, UK. The talk was "The role of acute imaging in stroke". |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.radiology.co.uk/meetings |
| Description | Stroke Association's Keynote Lecture given by Prof Joanna Wardlaw "One small vessel stroke? One giant problem for humankind" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | The Stroke Association's Keynote Lecture is a prestigious event that showcases the latest advancements being made in stroke research. In 2016, the Keynote Lecture was held at Lancaster House. Professor Wardlaw addressed 'small vessel disease' which is the most common cause of vascular dementia. Although vascular dementia is the second most common form of dementia, for too long there has been insufficient research into this disease. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.stroke.org.uk/news/keynote-lecture-2016 |
| Description | Symposium on Small Vessel Disease of the Brain - Prof Joanna Wardlaw gave a talk on "Small vessel disease: stroke and dementia" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw gave a talk at the Symposium on Small Vessel Disease of the Brain organised by Novo Nordisk Fonden, 11 May 2017, Hellerup, Denmark. The talk was on "Small vessel disease: stroke and dementia". |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://novonordiskfonden.dk/en/content/small-vessel-disease-brain-epidemic-21st-century |
| Description | The Row Fogo Centre for Research into Ageing and the Brain website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Being officially recognised as a Research Centre in 2018, The Row Fogo Centre for Research into Ageing and the Brain launched a new website. The website is directed in multiple audiences. Content includes a comprehensive description of the Centre research activity, updates on recent publications, news and organised events. The website contains information for PhD candidates and medical imaging researchers about related programmes and courses, and for visiting staff and students on how to join SVD Research Groups. The website gives a breadth of ways to fundraise and donate to support SVD research. |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.ed.ac.uk/clinical-brain-sciences/research/row-fogo-centre |
| Description | UK Stroke Assembly, talk by Prof Joanna Wardlaw: "Stroke and dementia: what research tells us" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Prof Joanna Wardlaw was invited to give a talk at the UK Stroke Assembly from 13-14 June 2016 in Nottingham, UK. the talk was entitled: "Stroke and dementia: what research tells us". |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.stroke.org.uk/take-action/uk-stroke-assembly |
| Description | World Stroke Organisation Women in Stroke Initiative, 2021, showcasing the work of women who have made major contributions to advancing care of patients with stroke |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | https://www.world-stroke.org/news-and-blog/blogs/womeninstroke-initiative-our-nominees |
| Year(s) Of Engagement Activity | 2021 |
| Description | prof Joanna Wardlaw talk 'Stroke in the small vessels: recent clinical, mechanistic and potential therapeutic insights", The Eric Corey Raps Memorial Lecture 2021, The University of Pennsylvania Medical Centre, 10th Feb 2021, Pennsylvania, USA, virtual |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | prof Joanna Wardlaw talk 'Stroke in the small vessels: recent clinical, mechanistic and potential therapeutic insights", The Eric Corey Raps Memorial Lecture 2021, The University of Pennsylvania Medical Centre, 10th Feb 2021, Pennsylvania, USA, virtual |
| Year(s) Of Engagement Activity | 2021 |