MICA: Health e-Research Centre
Lead Research Organisation:
University of Manchester
Department Name: School of Health Sciences
Abstract
The Health e-Research Centre (HeRC) will turn under-used electronic health data in Northern England into new knowledge and improved healthcare. The under-used data sources include NHS and health science databases. HeRC will develop Health Informatics (HI) methods to clean up and link up the different data sources in ways that give a bigger picture of patterns of health and how patients respond to treatments. As well as linking data to data, HeRC will link data, analytical methods and experts together in order to make more timely and accurate findings.
HeRC seeks to unlock the potential in the current islands of data, methods and expertise by joining them in three streams of work: 1) researching and developing HI methodology to make linked health data more available for analysis; 2) applying HI and related methodology, such as computational statistics, to solve previously intractable health science and service questions; and 3) training a new cadre of health informaticians to drive their methodology and its support of cutting-edge research.
In contrast to data captured purely for research, data generated during the provision of healthcare are incomplete, inaccurate and subject to variation in recording. HeRC will explore the effects of patients and clinicians recording health and healthcare information together, for example where patients have on-line access to their GP records. HeRC will also prepare for the deluge of patient reported data from technologies such as smartphones.
The practical questions that researchers face when using health records will be addressed, for example: Which data are available and where? Do I have permission to use the data? What can I learn from other who used similar data? Software will be developed to provide a research environment that embeds key methods so that they can be learnt and used. The research environment will also embed datasets, making them discoverable, whilst maintaining high standards of information governance.
Five research programmes will maximise the value of using linked health data for research: The CoOP (Co-producing Observations with Patients) programme will consider how technologies can be made sufficiently 'engaging' for patients to use them frequently enough to provide important signals that are missing from usual healthcare records. The MOD (Missed Opportunities Detector) will enable linked data to be used to answer questions such as "for these patients who were admitted to hospital with a heart attack, was a prevention opportunity missed somewhere in the system, in public health, general practice or more specialist care?" Such information can be used to target resources to where a community needs them most. The SEA-3 (Scalable Endotypes of Allergies, Asthma and Andrology) will use HI and advanced statistics to help identify patients who appear to have a different form of asthma etc. where different kinds of prevention or treatment are needed. The DOT (Diabesity Outcome Translator) is about speeding up the answering of important questions by getting researchers in different places to work on different kinds of linked data together at the same time - tackling questions such as "what is the cancer risk of common drug treatments for diabetes?". The FIN (Feasibility Improvement Network) will look at how clinical trials for testing new treatments can be better planned so that the numbers of people who actually take part over a particular time period match the estimates that are made using linked data before the trial starts.
To deliver HeRC, the consortium will integrate Northern England's top centres for statistics at Lancaster, public health at Liverpool, computer science at Manchester, and health economics/services research at York. This integration will extend to the NHS, building on a promising model (NHS e-lab) of patient, public and community involvement in the trustworthy reuse of health data for research.
HeRC seeks to unlock the potential in the current islands of data, methods and expertise by joining them in three streams of work: 1) researching and developing HI methodology to make linked health data more available for analysis; 2) applying HI and related methodology, such as computational statistics, to solve previously intractable health science and service questions; and 3) training a new cadre of health informaticians to drive their methodology and its support of cutting-edge research.
In contrast to data captured purely for research, data generated during the provision of healthcare are incomplete, inaccurate and subject to variation in recording. HeRC will explore the effects of patients and clinicians recording health and healthcare information together, for example where patients have on-line access to their GP records. HeRC will also prepare for the deluge of patient reported data from technologies such as smartphones.
The practical questions that researchers face when using health records will be addressed, for example: Which data are available and where? Do I have permission to use the data? What can I learn from other who used similar data? Software will be developed to provide a research environment that embeds key methods so that they can be learnt and used. The research environment will also embed datasets, making them discoverable, whilst maintaining high standards of information governance.
Five research programmes will maximise the value of using linked health data for research: The CoOP (Co-producing Observations with Patients) programme will consider how technologies can be made sufficiently 'engaging' for patients to use them frequently enough to provide important signals that are missing from usual healthcare records. The MOD (Missed Opportunities Detector) will enable linked data to be used to answer questions such as "for these patients who were admitted to hospital with a heart attack, was a prevention opportunity missed somewhere in the system, in public health, general practice or more specialist care?" Such information can be used to target resources to where a community needs them most. The SEA-3 (Scalable Endotypes of Allergies, Asthma and Andrology) will use HI and advanced statistics to help identify patients who appear to have a different form of asthma etc. where different kinds of prevention or treatment are needed. The DOT (Diabesity Outcome Translator) is about speeding up the answering of important questions by getting researchers in different places to work on different kinds of linked data together at the same time - tackling questions such as "what is the cancer risk of common drug treatments for diabetes?". The FIN (Feasibility Improvement Network) will look at how clinical trials for testing new treatments can be better planned so that the numbers of people who actually take part over a particular time period match the estimates that are made using linked data before the trial starts.
To deliver HeRC, the consortium will integrate Northern England's top centres for statistics at Lancaster, public health at Liverpool, computer science at Manchester, and health economics/services research at York. This integration will extend to the NHS, building on a promising model (NHS e-lab) of patient, public and community involvement in the trustworthy reuse of health data for research.
Technical Summary
The Health e-Research Centre (HeRC) will turn under-used electronic health data in Northern England into new knowledge and improved healthcare. The data sources include NHS and health science databases. HeRC will develop and apply Health Informatics (HI) methods to harness these disparate data sources through three streams of work: 1) researching and developing HI methodology to make linked health data more available for analysis; 2) applying HI methodology to solve previously intractable health science and service questions; and 3) training a new cadre of health informaticians to drive the methodology and its support of cutting-edge research.
In contrast to data captured purely for research, data generated during healthcare are incomplete, inaccurate and subject to variation in recording. HeRC will develop ways to improve data capture, including patient reported outcomes, and to handle variations in recording. Questions researchers face when using health records will be addressed, e.g.: Which data are available and where? Do I have permission to use the data? What can I learn from other who used similar data? Software will be developed to provide a research environment that embeds key methods so that they can be learnt and used. The research environment will also embed datasets, making them discoverable, whilst maintaining high standards of information governance.
Five research programmes will apply HeRC's methodology to cutting edge uses of linked health data across a spectrum of public health, clinical and health policy problems.
To deliver HeRC, the consortium will integrate Northern England' leading centres for statistics at Lancaster, public health at Liverpool, computer science at Manchester, and health economics/services research at York. This integration will extend to the NHS, building on a promising model (NHS e-lab) of patient, public and community involvement in the trustworthy reuse of health data for research.
In contrast to data captured purely for research, data generated during healthcare are incomplete, inaccurate and subject to variation in recording. HeRC will develop ways to improve data capture, including patient reported outcomes, and to handle variations in recording. Questions researchers face when using health records will be addressed, e.g.: Which data are available and where? Do I have permission to use the data? What can I learn from other who used similar data? Software will be developed to provide a research environment that embeds key methods so that they can be learnt and used. The research environment will also embed datasets, making them discoverable, whilst maintaining high standards of information governance.
Five research programmes will apply HeRC's methodology to cutting edge uses of linked health data across a spectrum of public health, clinical and health policy problems.
To deliver HeRC, the consortium will integrate Northern England' leading centres for statistics at Lancaster, public health at Liverpool, computer science at Manchester, and health economics/services research at York. This integration will extend to the NHS, building on a promising model (NHS e-lab) of patient, public and community involvement in the trustworthy reuse of health data for research.
Planned Impact
Commercial private sector beneficiaries: HeRC involves companies from three sectors: life science, information and communications technologies (ICT) and management consultancy/intelligence. For the life science sector, HeRC is set to reduce the cost of clinical trials through more accurate feasibility analysis, better design and more efficient recruitment and trial management. HeRC will also help companies to better target their therapies through studying clinical effectiveness with real world data. The NHS e-lab system will enable companies to do more detailed analysis than is possible via the usual in-licensed data: this is achieved by NHS and academic organisations coming together as trusted third parties to perform analyses within clinical information governance. HeRC will provide a suite of software and procedures to help such partnerships to form. This is directly in line with the Government's Life Science Strategy. In years 1-5 HeRC will be able to incorporate and enhance the world's largest open-label respiratory trial, GSK's Salford Lung Study. For the ICT sector, HeRC will provide a real-world system for developing mobile health solutions and health applications of machine learning technologies. Mobile device manufacturers wish to partner with HeRC via the Manchester m-Health Ecosystem in developing mobile health assessment methods. In addition to blue chip companies, there is considerable scope for small to medium sized enterprises in the Northern England to commercialise the intellectual property that HeRC is set to generate.
Policy-maker beneficiaries: At the level of local health systems, policy makers will be able to use HeRC's methods and tools to inform the targeting of resources to the areas of greatest need. Similar techniques could be employed to identify patients at high risk of acute exacerbations of a long term conditions, where early intervention might prevent the exacerbation. At the national level, HeRC tools could be deployed across linked data resources such as those of the NHS Information Centre to reduce the cost and increase the quality of the intelligence the NHS buys for commissioning and quality improvement purposes. At the international level, HeRC is set to work with US and EU colleagues to enable comparable analyses to be run across different health information systems to achieve large-scale semantic interoperability of research using health record data. Within the EU, HeRC will help the researchers using its tools to be compliant with forthcoming directives and regulations.
Public sector and third sector beneficiaries: The data processing methods and tools that HeRC will develop for researchers will meet many of the intelligence needs of public services wishing to make better use of their data. As public services move toward integrated records across primary care, secondary care and social care, data supply is no longer the barrier to information. That barrier is now access to methods and skills to make sense of the very complex data. The HeRC tools will make it easier for public services to share templates for analysis and enrich interpretation of results through networked analysis methods that draw on social computing techniques.
Wider public beneficiaries: HeRC will promote the "citizen scientist" model of involvement. HeRC's methodology will make the uses of linked data more transparent, enabling citizens to see how their personal data is being used in research. The same transparency could help to democratise aspects of decision-making over the development of local public services. In addition, the research HeRC will carry out to improve the capture of patient reported outcomes will help to tune healthcare to achieve the outcomes that matter most to patients.
Policy-maker beneficiaries: At the level of local health systems, policy makers will be able to use HeRC's methods and tools to inform the targeting of resources to the areas of greatest need. Similar techniques could be employed to identify patients at high risk of acute exacerbations of a long term conditions, where early intervention might prevent the exacerbation. At the national level, HeRC tools could be deployed across linked data resources such as those of the NHS Information Centre to reduce the cost and increase the quality of the intelligence the NHS buys for commissioning and quality improvement purposes. At the international level, HeRC is set to work with US and EU colleagues to enable comparable analyses to be run across different health information systems to achieve large-scale semantic interoperability of research using health record data. Within the EU, HeRC will help the researchers using its tools to be compliant with forthcoming directives and regulations.
Public sector and third sector beneficiaries: The data processing methods and tools that HeRC will develop for researchers will meet many of the intelligence needs of public services wishing to make better use of their data. As public services move toward integrated records across primary care, secondary care and social care, data supply is no longer the barrier to information. That barrier is now access to methods and skills to make sense of the very complex data. The HeRC tools will make it easier for public services to share templates for analysis and enrich interpretation of results through networked analysis methods that draw on social computing techniques.
Wider public beneficiaries: HeRC will promote the "citizen scientist" model of involvement. HeRC's methodology will make the uses of linked data more transparent, enabling citizens to see how their personal data is being used in research. The same transparency could help to democratise aspects of decision-making over the development of local public services. In addition, the research HeRC will carry out to improve the capture of patient reported outcomes will help to tune healthcare to achieve the outcomes that matter most to patients.
Organisations
- University of Manchester (Collaboration, Lead Research Organisation)
- NHS England (Collaboration)
- ASTON UNIVERSITY (Collaboration)
- IBM (Collaboration)
- Northern Health Science Alliance Ltd (NHSA) (Collaboration)
- Manchester Institute for Collaborative Research on Ageing (Collaboration)
- University of Sheffield (Collaboration)
- Royal Veterinary College (RVC) (Collaboration)
- Manchester City Football Club (Collaboration)
- Institute of Clinical and Evaluative Sciences (ICES) (Collaboration)
- UNIVERSITY OF SOUTHAMPTON (Collaboration)
- AGE UK (Collaboration)
- Manchester Community Central (Collaboration)
- HARVARD UNIVERSITY (Collaboration)
- University of Wisconsin-Madison (Collaboration)
- ANIMAL HEALTH TRUST (Collaboration)
- Inspiring Communities Together (Collaboration)
- British Kidney Patient Association (Collaboration)
- MERCK (Collaboration)
- The Office for Creative Research (OCR) (Collaboration)
- Google (Collaboration)
- N8 Universities (Collaboration)
- Alan Turing Institute (Collaboration)
- Health Unlocked (Collaboration)
- Academic Health Science Network for the North East and North Cumbria (Collaboration)
- Janssen Research & Development (Collaboration)
- British Broadcasting Corporation (BBC) (Collaboration)
- UNIVERSITY OF SALFORD (Collaboration)
- uMotif (Collaboration)
- Servier Laboratories (Collaboration)
- SALFORD ROYAL NHS FOUNDATION TRUST (Collaboration)
- UNIVERSITY OF BRADFORD (Collaboration)
- University of Malawi (Collaboration)
- Roma Tre University (Collaboration)
- Nokia (Collaboration)
- MRC Dementias Platform UK (Collaboration)
- International Foundation for Infectious Diseases and Health (Collaboration)
- Manchester City Council (Collaboration)
- Animal and Plant Health Agency (Collaboration)
- LumiraDx (Collaboration)
- Heywood Middleton and Rochdale CCG (Collaboration)
- Asda Stores Limited (Collaboration)
- AstraZeneca (Collaboration)
- UNIVERSITY OF EDINBURGH (Collaboration)
- Verily Life Sciences LLC (Collaboration)
- North West Coast Greater Manchester Academic Health Science Network (Collaboration)
- University of Bristol (Collaboration)
- UNIVERSITY OF LEICESTER (Collaboration)
- UNIVERSITY OF NOTTINGHAM (Collaboration)
- MANCHESTER UNIVERSITY NHS FOUNDATION TRUST (Collaboration)
- Renal Association (Collaboration)
- National Institute for Health Research (Collaboration)
- Association of the British Pharmaceutical Industry (Collaboration)
- IMPERIAL COLLEGE LONDON (Collaboration)
- researchobject.org (Collaboration)
- Yorkshire and Humber Academic Health Science Network (Collaboration)
- National Institute for Health and Care Excellence (NICE) (Collaboration)
- Intelligent Medical Objects (Collaboration)
- Farr Institute of Health Informatics Research (Collaboration)
- Ernst and Young LLP (Collaboration)
- Informatics for Integrating Biology and the Bedside (i2b2) (Collaboration)
Publications
Abbing-Karahagopian V
(2014)
Antidepressant prescribing in five European countries: application of common definitions to assess the prevalence, clinical observations, and methodological implications.
in European journal of clinical pharmacology
Abbing-Karahagopian V
(2014)
Bridging differences in outcomes of pharmacoepidemiological studies: design and first results of the PROTECT project.
in Current clinical pharmacology
Achttien RJ
(2015)
Development of evidence-based clinical algorithms for prescription of exercise-based cardiac rehabilitation.
in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
Agier L
(2013)
A multi-state spatio-temporal Markov model for categorized incidence of meningitis in sub-Saharan Africa.
in Epidemiology and infection
Ainsworth J
(2015)
Combining Health Data Uses to Ignite Health System Learning.
in Methods of information in medicine
Ainsworth J
(2013)
A comparison of two delivery modalities of a mobile phone-based assessment for serious mental illness: native smartphone application vs text-messaging only implementations.
in Journal of medical Internet research
Aitken M
(2019)
Consensus Statement on Public Involvement and Engagement with Data-Intensive Health Research
in IJPDS International Journal of Population Data Science
Aitken M
(2019)
Consensus Statement on Public Involvement and Engagement with Data Intensive Health Research.
in International journal of population data science
Akbarov A
(2015)
A Two-stage Dynamic Model to Enable Updating of Clinical Risk Prediction from Longitudinal Health Record Data: Illustrated with Kidney Function.
in Studies in health technology and informatics
| Title | Additional file 4: of A systematic review of electronic audit and feedback: intervention effectiveness and use of behaviour change theory |
| Description | Study specific bias assessment. (TIF 5143 kb) |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2017 |
| URL | https://springernature.figshare.com/articles/figure/Additional_file_4_of_A_systematic_review_of_elec... |
| Title | Additional file 4: of A systematic review of electronic audit and feedback: intervention effectiveness and use of behaviour change theory |
| Description | Study specific bias assessment. (TIF 5143 kb) |
| Type Of Art | Film/Video/Animation |
| Year Produced | 2017 |
| URL | https://springernature.figshare.com/articles/figure/Additional_file_4_of_A_systematic_review_of_elec... |
| Title | Arthur, the Pain Mannequin: Come Pain or Shine |
| Description | Local artist Sophie Tyrrell collaborated with Cloudy to design and create a beautiful and enormous articulated figure called Arthur, suspended within a 7m high rig (or 'pain prison'). The frame would act as a metaphor for pain, with the figure trapped within it. Sophie took her inspiration from Greek classical sculpture and used the cubist style of Picasso to build Arthur. Members of the public were invited by 'weatherman' Michael Kipper (see picture on the right) to select a piece of fabric representing their pain levels over the past couple of weeks and post it on to the relevant body part of a smaller version of Arthur (below). Manchester-based community circus company, The Circus House, used counterweights and their aerial artistry for visually stunning performances where the audience saw their pain attached to Arthur. |
| Type Of Art | Artwork |
| Year Produced | 2016 |
| Impact | 500 people engaged with the installation and 'pinned their pain' to the mannequin. raised awareness of musculoskeletal conditions with the general public. |
| URL | https://www.cloudywithachanceofpain.com/blog/meet-local-artist-sophie-tyrell-designer-and-creator-of... |
| Title | Cloudy with a Chance of Pain Immersive Data Walkway |
| Description | Our New York-based project partners, the Office for Creative Research (OCR), designed and constructed a physical representation of data collected from February 1st- 14th 2016 in the Manchester area. Each red banner illustrated the level of pain a person reported feeling during this time period, with a greater level of pain corresponding to a spot closer to the ground. On the ends are two different coloured banners. The yellow shows the average temperature per day for this time period with a low of around 3°c to a high of 10°c with the higher temperature being closer to the ground. The blue shows the adjusted sea level pressure. People were invited to walk through and see if they can make a connection between the weather and the levels of pain. |
| Type Of Art | Artwork |
| Year Produced | 2016 |
| Impact | 300 people engaged with the walkway and talked to the volunteers to find out more about the citizen science project. Raised awareness amongst the general public of citizen science, |
| URL | https://ocr.nyc/public-space-interventions/2016/06/15/cloudy-manchester-day/ |
| Description | Advanced notice of HeRC led Citizens Jury findings requested by the government to inform the forthcoming National Data Guardian Review |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Impact | Government has requested advanced notice of the findings of the HeRC led Citizen's Jury's so that it may inform the forthcoming National Data Guardian Review. Led by researchers from The University of Manchester, each three day citizens' jury included testimony from five expert witnesses including advocates drawn from both sides of the debate. In total, 34 members of the public, chosen to provide a balanced representation of society, were tasked with answering the same charge: "to what extent should patients control access to patient records?" Independently facilitated and following much debate, 33 out of 34 jurors, chosen to broadly represent the public in England, voted in support a health database being created, with 24 choosing to give individuals the right to opt out and 6 favouring an opt-in model MP and Minister for Life Sciences George Freeman said: "These findings are really encouraging. The Government believes that the safe re-use of patient data for public benefit is important and we are working with relevant bodies to ensure that is achieved as quickly and safely as possible." |
| URL | https://www.gov.uk/government/consultations/the-role-of-the-national-data-guardian-for-health-and-so... |
| Description | Chair of the Farr Institute for Health Informatics Research eInfrastructure Working Group |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Children's Health And Monitoring Programme (CHAMP) is recognised by the Royal Society for Public Health |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Influenced training of practitioners or researchers |
| URL | https://www.rsph.org.uk/en/about-us/latest-news/press-releases/press-release1.cfm/pid/CB92F740-4FA4-... |
| Description | Citizens Jury Event: Patients' Control over Patient Records for Policy Makers including Dame Fiona Caldicott |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Impact | Policymakers from across UK health services will on Thursday (10 March) be presented with the results of two independent citizens' juries, both indicating support for the use of electronic health records to improve health and benefit the public. Over 40 decision makers including the National Data Guardian, Dame Fiona Caldicott and the Information Commissioner, Christopher Graham, will attend the announcement which may influence future plans regarding how health data - for example the information contained in GP records and data held by hospitals - are used. The jury's findings highlight that when informed of both of the risks and opportunities associated with health data sharing, the public believe an individual's right to privacy should not prevent research that can benefit patients overall. The juries also concluded that patients should be notified of information sharing schemes and have the right to 'opt-out' if they so choose. |
| URL | http://www.manchester.ac.uk/discover/news/citizens-jury-says-share-my-data-following-the-uks-first-e... |
| Description | Cloudy with a Chance of Pain referred to as an exemplar in PPIE by Simon Denegri (Chair, INVOLVE) in opening conference plenaries |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Contribution to HRA report: Identifying & recruiting participants for health research |
| Geographic Reach | National |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| URL | http://www.hra.nhs.uk/documents/2015/07/hra-sciencewise-dialogue-report-final-july-2015-recruiting-p... |
| Description | Contribution to Oglesby Trust report on inequalities in health |
| Geographic Reach | National |
| Policy Influence Type | Citation in other policy documents |
| URL | http://www.oglesbycharitabletrust.co.uk/media/7171/A_SHARED_RESPONSIBILITY_NOV2015-FINAL-FULL-VERSIO... |
| Description | Contribution to The Academy of Medical Sciences Symposium report on Reproducibility and Reliability of Biomedical Research: Improving Research Practice |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| URL | http://www.acmedsci.ac.uk/policy/policy-projects/reproducibility-and-reliability-of-biomedical-resea... |
| Description | Contribution to discussions at Information Technology in Healthcare Policy Forum to address the question: Why is the UK moving so slowly to realise the healthcare opportunities offered by information technology? |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| URL | http://www.policyprojects.com/ |
| Description | DataWell Contract |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Citation in other policy documents |
| Impact | Award of DataWell contract to Lumira used specifications for federated data queries originating in the HeRC research team in collaboration with GM AHSN: http://www.gmahsn.org/en/datawell - now underpinning data feeds into Farr supported analytics that has major policy impact in how health and social care will be targeted as GM devolves from NHS England. Increasing inward investment as Lumira plan to create 1500 jobs in Manchester working on digital health diagnostics. |
| URL | http://www.gmahsn.org/en/datawell |
| Description | Delivery of Health Informatics teaching on Modernising Scientific Careers for HI pathway in clinical bioinformatics NHS training programme |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Farr Institute Innovative Governance Working Group |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | HeRC Director led discussion with HM Treasury delegation on eHealth and graphene. |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | HeRC H@PPI Forum submission to National Data Guardian Consultation for Health and Social Care |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| URL | https://www.gov.uk/government/consultations/the-role-of-the-national-data-guardian-for-health-and-so... |
| Description | Health North: Connected Health Cities |
| Geographic Reach | National |
| Policy Influence Type | Citation in other policy documents |
| Impact | Approach from HM Treasury in December 2014 to generate ideas for the Health North investments in Health Science in North England resulted in Farr Health Informatics being selected as the sole area to be supported, under the Connected Health Cities £20m pilots, which in turn has resulted in major policy and industry impact: mentioned in all Budget speeches since March 2015 and Autumn Statement; increasing inward investment from companies such as Lumira who plan to create 1500 jobs in Manchester working on digital health and diagnostics linked to the data feed for Connected Health City Greater Manchester - other companies such as Intel and CISCO are also moving employees into the Science Park around the Connected Health Cities Ark sites. It has also influenced civic informatics policy such as the writing of GM Connect for very large scale data integration as part of the Greater Manchester devolution project. Public Health England, NICE, NHS England, HSCIC and DH all mention Connected Health Cities in official documentation over the past year and have invited presentations to senior stakeholder groups. |
| URL | http://www.manchester.ac.uk/discover/news/chancellors-20m-to-use-cities-data-to-improve-healthcare |
| Description | Incorporating collection of patient-reported outcomes into the national clinical audit for renal services in the UK |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Impact | As the co-chair of the Measurement workstream for NHS England's Think Kidneys programme, I have advised the UK Renal Registry (UKRR) on how to integrate patient-reported outcomes in their national audit scheme for renal services. Endorsement of the advice by the UKRR has resulted in routine collection of patient-reported outcome data since 2016, with more than 5,000 kidney patients having submitted data so far. Another key output of my chairing the workstream has been the development of a validated instrument to measure kidney patients' experiences. For this, I transferred results from my PhD research on developing a similar instrument for kidney patients in the Netherlands. The UK instrument has been adopted for annual data collection by the UKRR, and completed by 18,500 patients from over 50 renal units over the last two years. Results have been reported back to renal units to inform redesign of local healthcare services. |
| URL | https://www.thinkkidneys.nhs.uk/ckd/ |
| Description | Invitation to attend an Academy of Medical Sciences event to discuss the implementation of recommendations made in the 2013 report 'Realising the potential of stratified medicine' |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | LCR Innovation Board |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Led a UoM and Farr-wide response to an invitation to provide input to EU green paper on mobile health |
| Geographic Reach | Asia |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| URL | http://ec.europa.eu/digital-agenda/en/news/green-paper-mobile-health-mhealth |
| Description | Member of Information Skills Development Network Steering Group |
| Geographic Reach | Local/Municipal/Regional |
| Policy Influence Type | Participation in a guidance/advisory committee |
| Description | Member of the British Veterinary Association Surveillance working group |
| Geographic Reach | National |
| Policy Influence Type | Participation in a guidance/advisory committee |
| URL | https://www.bva.co.uk/uploadedFiles/Content/News_campaigns_and_policy/Policy/Animal_disease_surveill... |
| Description | Member of the National eInfrastructure Programme Directors Group |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | Minister for Life Sciences visit to HeRC |
| Geographic Reach | National |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| URL | http://www.herc.ac.uk/2016/03/08/manchesters-digital-health-revolution-gets-minister-measuring-his-h... |
| Description | Ministerial Industry Strategy Group - Expert Reference Group |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | New guidance being developed following public dialogue on health research |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Impact | Following the public dialogue project carried out with Sciencewise support at the end of 2014, the Health Research Authority (HRA) has been revising their Policy Framework for Health and Social Care Research prior to a formal consultation, following an informal call for comments earlier in the year. In addition the HRA has recently been developing guidance on two specific issues based on the input of the public and patient participants at the public dialogue: • The first set of guidance focuses on proportionate consent for simple pragmatic clinical trials. The HRA will be putting out their revised guidance on proportionate consent to formal consultation early next year. It is expected that the guidance will be finalised and launched in spring 2016. Prior to the formal consultation process, and in order to raise the profile of this issue among key stakeholders, the HRA is holding an event on 3rd December 2015 at Oxford Town Hall. Speakers will include Ben Goldacre, Iain Chalmers and Tjeerd van Staa (who all contributed to the dialogue). The HRA will be presenting the dialogue results at this event. • The second set of guidance focuses on how people are identified and recruited to take part in health research, which has implications in terms of access to patient records and shared data. The HRA has been developing draft guidance but this is currently on hold pending the completion of a Government review of consent led by Dame Fiona Caldicott. The findings of the review may impact on the drafting of the guidance, which will therefore be completed following the publication of the review report. The HRA dialogue report was published in June 2015 (see www.sciencewise-erc.org.uk/cms/assets/Uploads/HRA-IRPHR-Dialogue-Report-Final-June-24-3.pdf); the evaluation report is expected to be published soon. |
| URL | http://www.sciencewise-erc.org.uk/cms/new-guidance-being-developed-following-public-dialogue-on-heal... |
| Description | Presentation at Policy Week 2015: Science Technology and Public Policy on UK Health and Wealth Transformation |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| URL | http://www.downtowninbusiness.com/policy-week-2015-science-technology-and-public-policy/ |
| Description | Supervisor for Summer School at the Allan Turing Institute |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Talk to the All-Party Parliamentary Group on Medical Research |
| Geographic Reach | National |
| Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
| Description | The development of Modernising Scientific Careers in Health Informatics curriculum |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | care.data expert reference group |
| Geographic Reach | National |
| Policy Influence Type | Membership of a guideline committee |
| Description | A Better Start |
| Amount | £48,969,270 (GBP) |
| Organisation | Big Lottery Fund |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 02/2025 |
| Description | A feasibility study of enhanced occupational therapy interventions for children and adolescents with central nervous system tumours in the first two years from diagnosis |
| Amount | £202,183 (GBP) |
| Funding ID | PB-PG-0211-24146 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2014 |
| End | 07/2016 |
| Description | ACTIF II |
| Amount | £176,120 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2016 |
| End | 03/2018 |
| Description | Actissist II |
| Amount | £1,322,558 (GBP) |
| Funding ID | MR/P026664/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2017 |
| End | 05/2020 |
| Description | Active Assistance for Psychological Therapy (Actissist) |
| Amount | £575,482 (GBP) |
| Funding ID | MR/L005301/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2013 |
| End | 06/2016 |
| Description | Active Assistance for Psychological Therapy (Actissist): |
| Amount | £500,000 (GBP) |
| Funding ID | MR/L005301/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 12/2016 |
| Description | Active Assistance for Psychological Therapy (Actissist): Software to improve access and adherence to CBT targeting key relapse indicators in psychosis |
| Amount | £465,812 (GBP) |
| Funding ID | MR/L005301/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2014 |
| End | 06/2016 |
| Description | Ad hoc funding |
| Amount | £74,315 (GBP) |
| Organisation | Health Education England |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2016 |
| End | 08/2017 |
| Description | Arthritis Research UK Centre for Epidemiology |
| Amount | £1,999,419 (GBP) |
| Funding ID | 21755 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2018 |
| End | 07/2023 |
| Description | Arthritis Research UK public engagement funding for Manchester Day |
| Amount | £10,700 (GBP) |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 06/2016 |
| Description | Assembling the Data Jigsaw |
| Amount | £1,488,789 (GBP) |
| Funding ID | OBF/43995 |
| Organisation | Nuffield Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2020 |
| End | 03/2024 |
| Description | Assessing iodine status and associated health outcomes in British women during pregnancy |
| Amount | £1,000,000 (GBP) |
| Organisation | Government of Catalonia |
| Department | Department of Health |
| Sector | Public |
| Country | Spain |
| Start | |
| Description | Avoiding patient harm through the application of prescribing safety indicators in English general practices (PRoTeCT) |
| Amount | £2,430,144 (GBP) |
| Funding ID | RP-PG-1214-20012 |
| Organisation | National Institute for Health Research |
| Department | Programme Grants for Applied Research (PGfAR) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2016 |
| End | 09/2021 |
| Description | Ben Brown Early Career Award |
| Amount | £1 (GBP) |
| Organisation | Chartered Institute for Information Technology |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2014 |
| End | 01/2015 |
| Description | Ben Brown Wellcome Trust Fellowship |
| Amount | £1 (GBP) |
| Funding ID | 104438/Z/14/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2014 |
| End | 01/2015 |
| Description | CHESS: CPRD-COPD Hawthorne Effect Study in Salford: A UK cohort study to characterise patients enrolled in the Salford Lung Study and to evaluate a potential Hawthorne effect |
| Amount | £400,000 (GBP) |
| Organisation | GlaxoSmithKline (GSK) |
| Sector | Private |
| Country | Global |
| Start | 01/2014 |
| End | 01/2016 |
| Description | CONNECT: Digital markers to predict psychosis relapse |
| Amount | £6,300,000 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2021 |
| End | 02/2026 |
| Description | CREW |
| Amount | $1,679,803 (USD) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2018 |
| End | 08/2019 |
| Description | CRUK National Awareness and Early Diagnosis Initiative: Development of a risk prediction tool for early cancer detection in patients with type 2 diabetes |
| Amount | £141,000 (GBP) |
| Funding ID | 17962 |
| Organisation | Cancer Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | Children's Respiratory Research Environment Workgroup (CREW) Year 4 |
| Amount | $10,307,000 (USD) |
| Funding ID | 5UH3OD023282-04 |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 08/2019 |
| End | 08/2020 |
| Description | Childrens Respiratory and Environmental Workgroup (CREW) |
| Amount | $1,679,803 (USD) |
| Funding ID | OD023282-01 |
| Organisation | National Institutes of Health (NIH) |
| Sector | Public |
| Country | United States |
| Start | 08/2016 |
| End | 08/2018 |
| Description | CityVerve |
| Amount | £685,597 (GBP) |
| Organisation | International University of Korea |
| Sector | Academic/University |
| Country | Korea, Republic of |
| Start | 06/2016 |
| End | 07/2018 |
| Description | Clinical Research Infrastructure Initiative: Clinical Proteomics Centre |
| Amount | £1,100,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 03/2017 |
| Description | Clinical Research Infrastructure Initiative: Single Cell Functional Genomics |
| Amount | £300,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 03/2017 |
| Description | Clinical Research Infrastructure Initiative: UK Dementia Platform |
| Amount | £484,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 03/2017 |
| Description | Cloudy with a chance of pain |
| Amount | £272,601 (GBP) |
| Funding ID | 21225 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 12/2015 |
| End | 12/2017 |
| Description | Combining physiological and biomedical data into a novel computer-aided risk score to support near real-time clinical decision making and determine its impact on quality/safety of care. |
| Amount | £500,000 (GBP) |
| Organisation | The Health Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | Computational methods for microbial next-generation sequencing data |
| Amount | £340,116 (GBP) |
| Funding ID | BB/M001121/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Connected Yorkshire: building a digital community across Yorkshire and Humber. |
| Amount | £4,000,000 (GBP) |
| Organisation | Department for Business, Energy & Industrial Strategy |
| Department | UK Science and Innovation Network |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | Connected orthopaedic rehabilitation devices for remote patient monitoring during post-surgery care |
| Amount | £81,905 (GBP) |
| Funding ID | 102119 |
| Organisation | TSB Bank plc |
| Sector | Private |
| Country | United Kingdom |
| Start | 12/2014 |
| End | 12/2016 |
| Description | Cross-Farr small awards |
| Amount | £15,000 (GBP) |
| Organisation | Farr Institute of Health Informatics Research |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 06/2016 |
| End | 07/2017 |
| Description | Demonstrating the feasibility of a Learning Health System for cancer diagnosis in Primary Care |
| Amount | £579,707 (GBP) |
| Funding ID | 25310 |
| Organisation | Cancer Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 03/2023 |
| Description | Department of Health Strategic award: Health North Connected Health Cities Coordinating Centre |
| Amount | £3,800,000 (GBP) |
| Organisation | Department of Health (DH) |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2016 |
| End | 12/2018 |
| Description | Department of Health, Policy Research Programme: Understanding the Nature and Frequency of Avoidable Significant Harm in Primary Care |
| Amount | £350,000 (GBP) |
| Organisation | Government of Catalonia |
| Department | Department of Health |
| Sector | Public |
| Country | Spain |
| Start | 08/2015 |
| End | 08/2016 |
| Description | Department of Health: Greater Manchester Connected Health Cities |
| Amount | £4,000,000 (GBP) |
| Organisation | Government of Catalonia |
| Department | Department of Health |
| Sector | Public |
| Country | Spain |
| Start | 01/2016 |
| End | 12/2018 |
| Description | Department of Health: Health North Coordinating Centre |
| Amount | £4,000,000 (GBP) |
| Organisation | Government of Catalonia |
| Department | Department of Health |
| Sector | Public |
| Country | Spain |
| Start | 01/2016 |
| End | 12/2018 |
| Description | Developing a UK-Korea Common Data and Modelling Bridge for Precision Treatment and Monitoring of Atrial Fibrillation |
| Amount | £9,975 (GBP) |
| Funding ID | MC_PC_18070 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2019 |
| End | 09/2020 |
| Description | Developing forecasting system for emergency hospital admissions |
| Amount | £60,000 (GBP) |
| Organisation | Alder Hey Children's NHS Foundation Trust |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2013 |
| End | 08/2014 |
| Description | Development and evaluation of an intervention to support Adherence to treatment in adults with Cystic Fibrosis |
| Amount | £440,693 (GBP) |
| Funding ID | RP-PG-1212-20015 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 10/2016 |
| Description | Diabetes UK Clinical Research Grant |
| Amount | £218,495 (GBP) |
| Funding ID | 14/0004971 |
| Organisation | Diabetes UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 01/2015 |
| End | 12/2018 |
| Description | DoH, Policy Research Programme: Understanding the Nature and Frequency of Avoidable Significant Harm in Primary Care |
| Amount | £350,000 (GBP) |
| Organisation | Government of Catalonia |
| Department | Department of Health |
| Sector | Public |
| Country | Spain |
| Start | 08/2015 |
| End | 08/2016 |
| Description | EMIF Platform |
| Amount | £1,443,359 (GBP) |
| Organisation | IMI plc |
| Sector | Private |
| Country | United Kingdom |
| Start | 03/2013 |
| End | 03/2018 |
| Description | EPSRC - NIHR HTC Partner-ship Award: Partnership with the MindTech HTC |
| Amount | £185,893 (GBP) |
| Funding ID | EP/M000346/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 04/2017 |
| Description | EPSRC DTP PhD Health data Sciences |
| Amount | £65,618 (GBP) |
| Organisation | Imperial College London |
| Department | EPSRC Centres for Doctoral Training |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 08/2017 |
| End | 03/2020 |
| Description | EPSRC DTP PhD Health data sciences |
| Amount | £65,618 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2017 |
| End | 03/2020 |
| Description | EPSRC Network for Mental Health Technologies (partnership with MindTech HTC) |
| Amount | £149,000 (GBP) |
| Funding ID | EP/M000346/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 03/2017 |
| Description | EPSRC: UK Health Data Analytics Network |
| Amount | £50,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2015 |
| End | 03/2016 |
| Description | Enhancing the credibility, usefulness and relevance of patient experience data in services for people with long-term physical and mental health conditions using digital data capture and improved analysis of narratives |
| Amount | £677,590 (GBP) |
| Funding ID | HS&DR/14/156/16 |
| Organisation | National Institute for Health Research |
| Department | Health Services and Delivery Research (HS&DR) Programme |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 04/2017 |
| Description | Enhancing the opportunities for patient segmentation and stratification in forefront clinical research |
| Amount | £17,251,607 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 04/2016 |
| Description | Enhancing the quality of psychological interventions delivered by telephone (EQUITy) |
| Amount | £2,524,745 (GBP) |
| Funding ID | RP-PG-1016-20010 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 10/2024 |
| Description | Farr Institute - North of England |
| Amount | £5,000,839 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2013 |
| End | 05/2014 |
| Description | Fellowship awarded to University of Manchester from National Productivity Investment Fund (NPIF). |
| Amount | £236,193 (GBP) |
| Organisation | Government of the UK |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2018 |
| End | 02/2021 |
| Description | GM Patient Safety Translational Research Centre |
| Amount | £7,000,000 (GBP) |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2017 |
| End | 07/2022 |
| Description | Generic roll-out of the Arthritis Research UK Catalogue of Studies |
| Amount | £15,000 (GBP) |
| Funding ID | 20878 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 06/2014 |
| End | 01/2016 |
| Description | GetReal: Incorporating real-life clinical data into drug development |
| Amount | € 250,000 (EUR) |
| Funding ID | 115546 |
| Organisation | European Commission |
| Department | Innovative Medicines Initiative (IMI) |
| Sector | Public |
| Country | Belgium |
| Start | 01/2014 |
| End | 12/2016 |
| Description | Greater Manchester Connected Health City |
| Amount | £4,000,000 (GBP) |
| Organisation | Government of Catalonia |
| Department | Department of Health |
| Sector | Public |
| Country | Spain |
| Start | 01/2016 |
| End | 12/2018 |
| Description | HDRUK Fellowships (TWO POSITIONS) |
| Amount | £600,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2018 |
| End | 02/2021 |
| Description | HSST in Health Informatics |
| Amount | £16,000 (GBP) |
| Organisation | Health Education England |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2018 |
| End | 08/2021 |
| Description | INBANK Scientific Lead (Research Funding Award) |
| Amount | £53,876 (GBP) |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2012 |
| End | 12/2014 |
| Description | Innovate UK : CityVerve |
| Amount | £10,000,000 (GBP) |
| Funding ID | 102561 |
| Organisation | Innovate UK |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2016 |
| End | 04/2018 |
| Description | Innovation grant |
| Amount | £39,516 (GBP) |
| Funding ID | IN_013_20160304 |
| Organisation | Kidney Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2016 |
| End | 08/2018 |
| Description | Innovation grant |
| Amount | £39,516 (GBP) |
| Organisation | Kidney Research UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 09/2016 |
| End | 10/2018 |
| Description | Insight Research Programme |
| Amount | £398,912 (GBP) |
| Organisation | UK Health Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 03/2021 |
| Description | Insight research programme |
| Amount | £398,912 (GBP) |
| Organisation | Health Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 04/2021 |
| Description | Liverpool City Region Civic Data Trust |
| Amount | £5,278,535 (GBP) |
| Organisation | Liverpool City Region Combined Authority |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2020 |
| End | 03/2025 |
| Description | MICA: NURTuRE - changing the landscape of renal medicine to foster a unified approach to stratified medicine |
| Amount | £2,589,391 (GBP) |
| Funding ID | MR/R013942/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2018 |
| End | 07/2024 |
| Description | MRC Clinical Research Infrastructure: Clinical Proteomics Centre |
| Amount | £12,932,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 03/2016 |
| Description | MRC Clinical Research Infrastructure: Dementia Platform UK |
| Amount | £17,251,000 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 03/2016 |
| Description | MRC Confidence in Concept 2 |
| Amount | £106,270 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2014 |
| End | 06/2015 |
| Description | MRC Research Grant |
| Amount | £3,576,156 (GBP) |
| Funding ID | MR/N024397/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2016 |
| End | 08/2021 |
| Description | MRC Stratified Medicine Initiative: Childhood arthritis and its associated uveitis: stratification through endotypes and mechanism to deliver benefit; the CLUSTER Consortium |
| Amount | £4,452,278 (GBP) |
| Funding ID | MR/R013926/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2018 |
| End | 04/2023 |
| Description | MRC Stratified Medicine grant STRATA 2 (Schizophrenia: Treatment Resistance and Therapeutic Advances) |
| Amount | £949,094 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2014 |
| End | 09/2019 |
| Description | MRC Stratified Medicine: MasterPlans |
| Amount | £5,225,104 (GBP) |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2015 |
| End | 05/2018 |
| Description | MRC: Manchester Molecular Pathology Innovation Centre |
| Amount | £2,900,000 (GBP) |
| Funding ID | MR/N00583X/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2015 |
| End | 09/2019 |
| Description | ManGO: Manchester Global Omics Initiative for Nutritional Health |
| Amount | £303,252 (GBP) |
| Funding ID | MC_PC_MR/R019118/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 02/2019 |
| Description | Manchester Biomedical Research Centre |
| Amount | £28,500,000 (GBP) |
| Funding ID | PSTRC-2016-003 |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 02/2022 |
| Description | Manchester Day public engagement funding |
| Amount | £6,000 (GBP) |
| Organisation | Manchester City Council |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 06/2016 |
| Description | Microsoft Research PhD Scholarship 2018 Programme (EPSRC CASE award with Microsoft) |
| Amount | £116,000 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2018 |
| End | 09/2022 |
| Description | MindTech 2.0 |
| Amount | £500,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 05/2019 |
| Description | NHS England: NHS Test Beds |
| Amount | £1,200,000 (GBP) |
| Organisation | NHS England |
| Sector | Public |
| Country | United Kingdom |
| Start | 01/2015 |
| End | 04/2017 |
| Description | NHS Graduate Management Training Scheme -Health Informatics |
| Amount | £237,600 (GBP) |
| Organisation | Health Education England |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2018 |
| End | 03/2021 |
| Description | NHSE: Patient Safety Collaborative for Yorkshire and Humberside |
| Amount | £2,000,000 (GBP) |
| Organisation | NHS England |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | NIHR CLAHRC North Wet Coast: Developing personalised renal function monitoring |
| Amount | £133,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | NIHR CLAHRC: Healthy children, healthy families: an applied public health research programme |
| Amount | £1,000,000 (GBP) |
| Organisation | National Institute for Health Research |
| Department | NIHR CLAHRC Yorkshire and Humber |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | NIHR HTA: EMPOWER |
| Amount | £115,497 (GBP) |
| Funding ID | HTA/13/154/04 |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 03/2019 |
| Description | NIHR HTA: Efficient Study Designs; Statin WISE N of 1 |
| Amount | £50,000 (GBP) |
| Organisation | National Institute for Health Research |
| Department | Health Technology Assessment Programme (HTA) |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | NIHR Health Service Delivery and Research: Experiences |
| Amount | £677,590 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2015 |
| End | 03/2017 |
| Description | NIHR Health Technology Assessment Programme |
| Amount | £800,000 (GBP) |
| Funding ID | 16/165/01 |
| Organisation | NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2017 |
| End | 10/2019 |
| Description | NIHR Research for Patient Benefit: Development of a core outcone set (COMET) for informed consent, clinical trials and treatment policy in patients with anal cancer |
| Amount | £229,000 (GBP) |
| Funding ID | PB-PG-1013-32064 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | NIHR RfPB: Development of a core outcome set for informed consent, clinical trials and treatment policy in patients with anal cancer (CORMAC) |
| Amount | £229,000 (GBP) |
| Funding ID | PB-PG-1013-32064 |
| Organisation | National Institute for Health Research |
| Department | Research for Patient Benefit |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2015 |
| End | 09/2017 |
| Description | NIHR Senior Investigator award for Prof Iain Buchan |
| Amount | £15,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 03/2018 |
| Description | NIHR: Improving Safety and Continuity Of Medicines Management At care Transitions |
| Amount | £2,000,000 (GBP) |
| Funding ID | RP-PG-0514-20009 |
| Organisation | National Institute for Health Research |
| Department | NIHR Biomedical Research Centre |
| Sector | Public |
| Country | United Kingdom |
| Start | |
| Description | National mortality audit and learning programme for UK. Health Quality and Improvement Programme. |
| Amount | £1,800,000 (GBP) |
| Organisation | The Health Quality Improvement Partnership (HQIP) |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | NewMind Plus Network |
| Amount | £630,510 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 06/2019 |
| Description | NewMind Plus Network |
| Amount | £157,628 (GBP) |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 06/2019 |
| Description | North Staffordshire Medical Institute: Major bleeding complications following acute myocardial infarction, site, frequency and impact; insight from a national and primary care |
| Amount | £250,000 (GBP) |
| Organisation | North Staffordshire Medical Institute |
| Sector | Hospitals |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 10/2019 |
| Description | PanORAMA project: Pancreatic cancer predisposition, Obesity-Related deposition Assessment using Magnetic resonance imAging |
| Amount | £150,000 (GBP) |
| Funding ID | 2013 RIF - Renehan |
| Organisation | Pancreatic Cancer UK |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 07/2013 |
| End | 07/2014 |
| Description | Personalised monitoring and enhanced self-management in mental health (CareLoop) |
| Amount | £1,100,000 (GBP) |
| Funding ID | MR/K015516/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2013 |
| End | 10/2015 |
| Description | Phase 2 IM2 Cystic Fibrosis Patient Adherence (Adult) |
| Amount | £9,982,808 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 01/2020 |
| Description | Project Grant: Sleep-RA |
| Amount | £249,990 (GBP) |
| Funding ID | 21188 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 03/2016 |
| End | 03/2019 |
| Description | Psoriasis Stratification to Optimise Relevant Therapy (PSORT) |
| Amount | £1,362,548 (GBP) |
| Funding ID | MR/L011808/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 02/2018 |
| Description | Remote Monitoring of Rheumatoid Arthritis (REMORA) |
| Amount | £196,785 (GBP) |
| Funding ID | 21126 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 04/2015 |
| End | 12/2016 |
| Description | SAVSNET: Developing the research potential of veterinary health informatics in the UK through growth, partnership and collaboration. |
| Amount | £730,461 (GBP) |
| Funding ID | BB/N019547/1 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 07/2016 |
| End | 07/2020 |
| Description | Scaling-up Packages of Interventions for Cardiovascular disease prevention in selected sites in Europe and Sub-Saharan Africa: An implementation research (SPICES Project) |
| Amount | € 5,902,038 (EUR) |
| Funding ID | 733356 |
| Organisation | European Union |
| Sector | Public |
| Country | European Union (EU) |
| Start | 01/2017 |
| End | 12/2021 |
| Description | Scaling-up packages of interventions for cardiovascular disease prevention in selected sites in Europe and sub-Saharan Africa: an implementation research (SPICES project) |
| Amount | £87,674 (GBP) |
| Funding ID | 733356 |
| Organisation | European Union |
| Sector | Public |
| Country | European Union (EU) |
| Start | 01/2017 |
| End | 12/2021 |
| Description | Social listening: Applying natural language processing methods to social media data to yield actionable analytics for health and care services |
| Amount | £300,577 (GBP) |
| Funding ID | MR/S004025/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2018 |
| End | 02/2021 |
| Description | Special Strategic Award: Cloudy with a Chance of Pain |
| Amount | £199,212 (GBP) |
| Funding ID | 21225 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2015 |
| End | 08/2017 |
| Description | Special Strategic Award: REMORA |
| Amount | £394,000 (GBP) |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 02/2015 |
| End | 02/2017 |
| Description | Supplementary Funding to Special Strategic Grant |
| Amount | £57,181 (GBP) |
| Funding ID | 21225 |
| Organisation | Versus Arthritis |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 08/2015 |
| End | 08/2017 |
| Description | The Christie Hosptial |
| Amount | £10,000 (GBP) |
| Organisation | The Christie NHS Foundation Trust |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2013 |
| End | 12/2013 |
| Description | The Health Foundation: Closing the gap: implementing a patient safety reporting tool in acute trusts. |
| Amount | £450,000 (GBP) |
| Organisation | The Health Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | The Health Foundation: Safety measurement and monitoring in health care. |
| Amount | £600,000 (GBP) |
| Organisation | The Health Foundation |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | The Wearable Clinic: Connecting Health, Self and Care |
| Amount | £1,639,303 (GBP) |
| Funding ID | EP/P010148/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 08/2021 |
| Description | The Wearable Clinic: Connecting Health, Self, and Care |
| Amount | £1,639,302 (GBP) |
| Funding ID | EP/P010148/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2017 |
| End | 02/2020 |
| Description | The future of 24/7 care |
| Amount | £343,017 (GBP) |
| Funding ID | HS&DR/12/128/48 |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2014 |
| End | 04/2017 |
| Description | The impact of body mass index on cancer-related survival in chemotherapy-naïve patients with non-metastatic colorectal and endometrial cancers: a federation meta-analysis of trial data |
| Amount | £150,000 (GBP) |
| Funding ID | 2016/1626 |
| Organisation | World Cancer Research Fund |
| Sector | Charity/Non Profit |
| Country | Global |
| Start | 02/2017 |
| End | 01/2019 |
| Description | The wearable clinic |
| Amount | £1,326,735 (GBP) |
| Funding ID | EP/P010148/1 |
| Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 04/2017 |
| End | 05/2020 |
| Description | Towards full use of available data to improve clinical outcome prediction |
| Amount | £30,000 (GBP) |
| Organisation | National Institute for Health Research |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2013 |
| End | 09/2014 |
| Description | UKHIRN - Farr Centre Infratructure Project Funding |
| Amount | £48,000 (GBP) |
| Organisation | Research Councils UK (RCUK) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2017 |
| End | 09/2018 |
| Description | UKRI/Rutherford Fund Fellowships at Health Data Research UK (HDR UK) |
| Amount | £300,000 (GBP) |
| Organisation | Science and Technologies Facilities Council (STFC) |
| Department | Ernest Rutherford Fellowship |
| Sector | Public |
| Country | United Kingdom |
| Start | 02/2018 |
| End | 02/2021 |
| Description | UNICORN (Unified Cohorts Research Network): Disaggregating asthma |
| Amount | £1,128,000 (GBP) |
| Funding ID | MR/S025340/1 |
| Organisation | Medical Research Council (MRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2020 |
| End | 02/2023 |
| Description | Use of the electronic health record in the design and conduct of clinical trials |
| Amount | £18,471 (GBP) |
| Funding ID | R40R |
| Organisation | Medical Research Council (MRC) |
| Department | Network of Hubs for Trials Methodology Research (HTMR) |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 11/2013 |
| End | 10/2014 |
| Description | Wellcome Trust ISSF |
| Amount | £4,850 (GBP) |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2016 |
| End | 06/2016 |
| Description | Wellcome Trust: British autozygosity population study of natural gene inactivation. |
| Amount | £2,500,000 (GBP) |
| Funding ID | 102627/B/13/Z |
| Organisation | Wellcome Trust |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | |
| Description | Workhorse - NIHR |
| Amount | £800,000 (GBP) |
| Organisation | NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 11/2017 |
| End | 10/2019 |
| Title | CliNER - Clinical NER |
| Description | CliNER is a Named-entity recognition software that extracts clinically relevant events and recognise and normalise temporal expressions., |
| Type Of Material | Data analysis technique |
| Year Produced | 2013 |
| Provided To Others? | Yes |
| Impact | A part of the set of tools developed for the i2b2 2012 challenge. |
| URL | http://gnode1.mib.man.ac.uk/hecta.html |
| Title | Clinical NorMA: temporal expression normaliser |
| Description | Clinical NorMA is a rule-based temporal expression normaliser explicitly designed for clinical data. It is open-source (GNU licence) and is written in Python. |
| Type Of Material | Data analysis technique |
| Year Produced | 2013 |
| Provided To Others? | Yes |
| Impact | State-of-the-art in temporal Information extraction |
| URL | http://gnode1.mib.man.ac.uk/hecta.html |
| Title | DOSES |
| Description | We introduce a prescription model that provides minimum and maximum values for dose number, frequency and interval, allowing modelling variability and flexibility within a drug prescription. We developed a text mining system that relies on rules to extract such structured information from prescription free-text dosage instructions. Our approach provides an accurate, automated way of coding prescription free text information, including information about flexibility and variability within a prescription. The method allows the researcher to decide how best to prepare the prescription data for drug efficacy and safety analyses in any given setting, and test various scenarios and their impact.gn |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2015 |
| Provided To Others? | Yes |
| Impact | We analysed over 56,000 most common free text prescriptions from CPRD records and found that 1 in 4 has inherent variability, i.e. a choice in taking medication specified by different minimum and maximum doses, duration or frequency. |
| URL | http://gnteam.cs.manchester.ac.uk/resources/doses/ |
| Title | Drug preparation algorithm |
| Description | Algorithm and reporting framework for increasing the efficiency and transparency of drug data preparation methods |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| Impact | Markedly increased the efficiency of data preparation for users |
| Title | Research Objects |
| Description | "Research Objects" describes an emerging approach to the publication, and exchange of scholarly information on the Web that aims to improve its reuse and reproducibility by: Supporting the publication of more than just PDFs, making data, code, and other resources first class citizens of scholarship Recognizing that sometimes there is a need to publish collections of these resources together as one shareable, cite-able resource. Enriching these resources and collections with any and all additional information required to make research reusable, and reproducible! Research objects are not just data, not just collections, but any digital resource that aims to go beyond the PDF for scholarly publishing. |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2010 |
| Provided To Others? | Yes |
| Impact | The notion of a Research Object has had a significant impact in the publishing and scholarly communications world -- the NIH BD2K Commons Initiative is based on Research Objects -- Research Objects formed the basis of the workflow reproducibility and preservation EU project Workflow4ever (http://www.wf4ever-project.org) which had an excellent rated final review. -- Research Objects have influenced the publisher community: NPG, F1000, GigaScience, Mozilla Science, Elsevier all have RO activities -- ROs won the Vision award in the 2nd Beyond the PDF International Conference -- RO principles are being incorporated in the EU RI ELIXIR interoperability workplan and the Force11.org Organisation. -- We have been invited to give numerous keynotes on ROs. |
| URL | http://www.researchobject.org |
| Title | Research Objects and Trustworthy Research Environments (eLabs) |
| Description | Digital research laboratories with consitent orchestration of algorithms over challenging data sources in healthcare |
| Type Of Material | Improvements to research infrastructure |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| Impact | Continued to feed www.researchobject.org and spawned the Trustworthy Research Environment deployments across www.connectedhealthcities.org and wider NHS |
| URL | https://www.herc.ac.uk/research_project/elab/ |
| Title | TERN: TEmporal expressions Recognizer and Normalizer |
| Description | Clinical temporal expressions recognizer and normaliser for unstructured clinical records (rubrics). |
| Type Of Material | Data analysis technique |
| Year Produced | 2013 |
| Provided To Others? | Yes |
| Impact | Used as part of clinical text mining challenges. |
| URL | http://gnode1.mib.man.ac.uk/hecta.html |
| Title | Additional file 1: of An external validation of models to predict the onset of chronic kidney disease using population-based electronic health records from Salford, UK |
| Description | Read codes used to extract the data from the Salford Integrated Record. (CSV 518 kb) |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/dataset/Additional_file_1_of_An_external_validation_of_... |
| Title | Additional file 1: of An external validation of models to predict the onset of chronic kidney disease using population-based electronic health records from Salford, UK |
| Description | Read codes used to extract the data from the Salford Integrated Record. (CSV 518 kb) |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/dataset/Additional_file_1_of_An_external_validation_of_... |
| Title | Additional file 1: of Outcome-sensitive multiple imputation: a simulation study |
| Description | Simulation code file 1 of 4. Generate data and obtain true estimates (making sure the simulations work as they should before incorporating the missing data mechanisms). Simulation code file 2 of 4. Main data generation file across missingness mechanisms (1 of 2). Simulation code file 3 of 4. Main data generation file across missingness mechanisms (2 of 2). Simulation code file 4 of 4. Summarise the simulation results in a data file. (ZIP 10Â kb) |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Outcome-sensitive_multiple... |
| Title | Additional file 1: of Outcome-sensitive multiple imputation: a simulation study |
| Description | Simulation code file 1 of 4. Generate data and obtain true estimates (making sure the simulations work as they should before incorporating the missing data mechanisms). Simulation code file 2 of 4. Main data generation file across missingness mechanisms (1 of 2). Simulation code file 3 of 4. Main data generation file across missingness mechanisms (2 of 2). Simulation code file 4 of 4. Summarise the simulation results in a data file. (ZIP 10Â kb) |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Outcome-sensitive_multiple... |
| Title | Additional file 2: of An external validation of models to predict the onset of chronic kidney disease using population-based electronic health records from Salford, UK |
| Description | R script to test QKidneyÂŽ. (R 7.88 kb) |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/dataset/Additional_file_2_of_An_external_validation_of_... |
| Title | Additional file 2: of An external validation of models to predict the onset of chronic kidney disease using population-based electronic health records from Salford, UK |
| Description | R script to test QKidneyÂŽ. (R 7.88 kb) |
| Type Of Material | Database/Collection of data |
| Year Produced | 2016 |
| Provided To Others? | Yes |
| URL | https://springernature.figshare.com/articles/dataset/Additional_file_2_of_An_external_validation_of_... |
| Title | Data from: Evaluation of a pharmacist-led actionable audit and feedback intervention for improving medication safety in primary care: an interrupted time series analysis |
| Description | Background. We evaluated the impact of a pharmacist-led Safety Medication dASHboard (SMASH) intervention on medication safety in primary care. Methods and findings. SMASH comprised: (1) training of clinical pharmacists to deliver the intervention; (2) a web-based dashboard providing actionable, patient-level feedback; and (3) pharmacists reviewing individual at-risk patients, and initiating remedial actions or advising general practitioners on doing so. It was implemented in forty-three general practices covering a population of 235,595 people in Salford (Greater Manchester), UK. All practices started receiving the intervention between 18 April 2016 and 26 September 2017. We used an interrupted time series analysis of rates of potentially hazardous prescribing and inadequate blood-test monitoring, comparing observed rates post-intervention to extrapolations from a 24-month pre-intervention trend. The number of people registered to participating practices and having one or more risk factors for being exposed to hazardous prescribing or inadequate blood-test monitoring at the start of the intervention was 47,413 (males: 23,073 [48.7%]; mean age: 60 [standard deviation: 21]). At baseline, 95% of practices had rates of potentially hazardous prescribing (composite of 10 indicators) between 0.88% and 6.19%. The prevalence of potentially hazardous prescribing reduced by 27.9% (95% confidence interval [CI], 20.3% to 36.8%) at 24 weeks and by 40.7% (95% CI, 29.1% to 54.2%) at twelve months after introduction of SMASH. The rate of inadequate blood-test monitoring (composite of 2 indicators) reduced by 22.0% (95% CI, 0.2% to 50.7%) at 24 weeks and by 23.5% (95% CI, -4.5% to 61.6%) at 12 months. After 12 months, 95% of practices had rates of potentially hazardous prescribing between 0.74% and 3.02%. We did not randomise practices but enrolled them in a naturalistic fashion. All our measurements were based on routinely kept electronic health records. Conclusions. The SMASH intervention was associated with reduced rates of potentially hazardous prescribing and inadequate blood-test monitoring in general practices. This reduction was sustained over 12 months after start of the intervention for prescribing but not for monitoring of medication. There was a marked reduction in the variation in rates of high-risk prescribing between practices. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2020 |
| Provided To Others? | Yes |
| URL | http://datadryad.org/stash/dataset/doi:10.5061/dryad.2280gb5p4 |
| Title | Dataset for: Investigation of two stage meta-analysis methods for joint longitudinal and time-to-event data through simulation and real data application |
| Description | Background: Joint modelling of longitudinal and time-to-event data is often preferred over separate longitudinal or time-to-event analyses as it can account for study dropout, error in longitudinally measured covariates, and correlation between longitudinal and time-to-event outcomes. The joint modelling literature focuses mainly on the analysis of single studies with no methods currently available for the meta-analysis of joint model estimates from multiple studies. Methods: We propose a two stage method for meta-analysis of joint model estimates. These methods are applied to the INDANA dataset to combine joint model estimates of systolic blood pressure (SBP) with time to death, time to myocardial infarction and time to stroke. Results are compared to meta-analyses of separate longitudinal or time-to-event models. A simulation study is conducted to contrast separate versus joint analyses over a range of scenarios. Results: Using the real dataset similar results were obtained using the separate and joint analyses. However, the simulation study indicated a benefit of use of joint rather than separate methods in a meta-analytic setting where association exists between the longitudinal and time-to-event outcomes. Conclusions: Where evidence of association between longitudinal and time-to-event outcomes exists, results from joint models over standalone analyses should be pooled in two stage meta-analyses. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| URL | https://figshare.com/articles/Dataset_for_Investigation_of_two_stage_meta-analysis_methods_for_joint... |
| Title | Dataset for: Investigation of two stage meta-analysis methods for joint longitudinal and time-to-event data through simulation and real data application |
| Description | Background: Joint modelling of longitudinal and time-to-event data is often preferred over separate longitudinal or time-to-event analyses as it can account for study dropout, error in longitudinally measured covariates, and correlation between longitudinal and time-to-event outcomes. The joint modelling literature focuses mainly on the analysis of single studies with no methods currently available for the meta-analysis of joint model estimates from multiple studies. Methods: We propose a two stage method for meta-analysis of joint model estimates. These methods are applied to the INDANA dataset to combine joint model estimates of systolic blood pressure (SBP) with time to death, time to myocardial infarction and time to stroke. Results are compared to meta-analyses of separate longitudinal or time-to-event models. A simulation study is conducted to contrast separate versus joint analyses over a range of scenarios. Results: Using the real dataset similar results were obtained using the separate and joint analyses. However, the simulation study indicated a benefit of use of joint rather than separate methods in a meta-analytic setting where association exists between the longitudinal and time-to-event outcomes. Conclusions: Where evidence of association between longitudinal and time-to-event outcomes exists, results from joint models over standalone analyses should be pooled in two stage meta-analyses. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2017 |
| Provided To Others? | Yes |
| URL | https://wiley.figshare.com/articles/dataset/Dataset_for_Investigation_of_two_stage_meta-analysis_met... |
| Title | Design of Trusted Research Environment between Connected Health Cities and Farr@HeRC |
| Description | The HeRC Trusted Research Environment is a scientific facility that provides secure data storage and computational capability for health data science. Prof John Ainsworth, HeRC/CHC, developed an infrastructure that connects directly into the NHS network meeting NHS Information Governance standards and is certified according to international ISO27001 information security standard. Beyond the infrastructure is delivered as an operational service to researchers who need a secure, managed environment for health data analytics. |
| Type Of Material | Database/Collection of data |
| Provided To Others? | No |
| Impact | Better and safer collection of data for use in research by CHC and Farr@HeRC. |
| URL | https://www.herc.ac.uk/research_project/elab/ |
| Title | PINGR and Medication Safety Dashboard primary care safety systems between NIHR Safety Centre and Farr@HeRC |
| Description | Software that analyses primary care electronic health records and provides feedback on quality of chronic care. Uniquely suggests tailored improvement actions for both organisations and individual patients. |
| Type Of Material | Data analysis technique |
| Provided To Others? | No |
| Impact | Implemented in 13 GP practices. Reported by users to be acceptable, and useful at improving patient care, by identifying undiagnosed conditions and therapy optimisation. Adopted by a Clinical Commissioning Group as a core part of their quality improvement programme. |
| Title | STELAR Asthma eLab |
| Description | The STELAR consortium has been set-up to develop and use a novel approach aiming to understand asthma by redefining endotypes of wheezing disorders during childhood, to elucidate their underlying mechanisms. The consortium comprises The University of Manchester and Aberdeen, and teams from NHS trusts in Bristol, the Isle of Wight and Manchester. The STELAR Asthma eLab has been developed to provide a secure web-based research environment to support consistent recording, description and sharing of data and emerging findings across existing UK asthma birth cohorts. Live data from contributing sites began to be uploaded on to the system in late 2014. |
| Type Of Material | Data handling & control |
| Year Produced | 2014 |
| Provided To Others? | Yes |
| Impact | It is anticipated that the eLab will be used for a variety of similar research collaborations. |
| URL | https://www.asthmaelab.org/share/page |
| Description | ABPI MoU signed for Greater Manchester |
| Organisation | Association of the British Pharmaceutical Industry |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | HeRC Director Iain Buchan met with James Weatherall, Head - Advanced Analytics Centre at AstraZeneca on 16 February 2017 to discuss the MoU signed with ABPI. MoU is regarding the pull-through of innovations into GM as a deep lab and staging post for early innovation. Prof Buchan provided a briefing to the GM health leaders and UK National Pharma Industry senior managers via emails with Chris Poole at Boehringer-Ingelheim (ABPI) in September 2016. |
| Collaborator Contribution | James Weatherall provided draft of MoU GM Pharma to Iain Buchan with suggestions of ways to incorporate projects relevant to HeRC. Chris Poole at Boehringer-Ingelheim Ltd (ABPI) sought Iain's advice on the joint GM Health Leaders and UK National Pharma Industry senior managers' roundtable meeting held 27 September 2016. |
| Impact | MoU written and signed for ABPI and Greater Manchester |
| Start Year | 2017 |
| Description | BBC Data Science Partnership |
| Organisation | British Broadcasting Corporation (BBC) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | All day visit to HeRC@Farr Headquarters (Jatin Aythora) hosted by Iain Buchan on 1 February 2017. HeRC PIs presented research and outputs; Public and Patient Involvement team presented their projects; met with HeRC Operations leads. |
| Collaborator Contribution | The BBC bring expertise and global vision on digital techonologies and horizon scanning. |
| Impact | Series of meetings are being scheduled by Iain Buchan and BBC Head of Technologies and a wider group from BBC including exective producers and other colleagues to develop a BBC-HeRC Data Science Partnership. Potential presence of BBC at the Farr Conference 2017 (Informatics for Health 2017). |
| Start Year | 2016 |
| Description | Childhood Obesity Research Group for Innovation (CORGI) |
| Organisation | Asda Stores Limited |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | HeRC staff conducting a series of 'mini-workshops' with existing parent groups in primary schools in Manchester to inform the development of mobile health technology solutions to tackle childhood obesity. |
| Collaborator Contribution | Direction and strategy |
| Impact | Multidiscplinary team comprising of NHS; public health; academia; smes; greatersport et al - to address the obesity epidemic in children and adults using innovative technologies. Final outputs from the workshops will be used to inform future technology development. CORGI team are currently applying for further funding from British Heart Foundation to develop mobile technology for children's healthy weight management. |
| Start Year | 2015 |
| Description | Childhood Obesity Research Group for Innovation (CORGI) |
| Organisation | British Broadcasting Corporation (BBC) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | HeRC staff conducting a series of 'mini-workshops' with existing parent groups in primary schools in Manchester to inform the development of mobile health technology solutions to tackle childhood obesity. |
| Collaborator Contribution | Direction and strategy |
| Impact | Multidiscplinary team comprising of NHS; public health; academia; smes; greatersport et al - to address the obesity epidemic in children and adults using innovative technologies. Final outputs from the workshops will be used to inform future technology development. CORGI team are currently applying for further funding from British Heart Foundation to develop mobile technology for children's healthy weight management. |
| Start Year | 2015 |
| Description | Childhood Obesity Research Group for Innovation (CORGI) |
| Organisation | Manchester City Council |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | HeRC staff conducting a series of 'mini-workshops' with existing parent groups in primary schools in Manchester to inform the development of mobile health technology solutions to tackle childhood obesity. |
| Collaborator Contribution | Direction and strategy |
| Impact | Multidiscplinary team comprising of NHS; public health; academia; smes; greatersport et al - to address the obesity epidemic in children and adults using innovative technologies. Final outputs from the workshops will be used to inform future technology development. CORGI team are currently applying for further funding from British Heart Foundation to develop mobile technology for children's healthy weight management. |
| Start Year | 2015 |
| Description | Childhood Obesity Research Group for Innovation (CORGI) |
| Organisation | Manchester City Football Club |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | HeRC staff conducting a series of 'mini-workshops' with existing parent groups in primary schools in Manchester to inform the development of mobile health technology solutions to tackle childhood obesity. |
| Collaborator Contribution | Direction and strategy |
| Impact | Multidiscplinary team comprising of NHS; public health; academia; smes; greatersport et al - to address the obesity epidemic in children and adults using innovative technologies. Final outputs from the workshops will be used to inform future technology development. CORGI team are currently applying for further funding from British Heart Foundation to develop mobile technology for children's healthy weight management. |
| Start Year | 2015 |
| Description | Childhood Obesity Research Group for Innovation (CORGI) |
| Organisation | Manchester University NHS Foundation Trust |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | HeRC staff conducting a series of 'mini-workshops' with existing parent groups in primary schools in Manchester to inform the development of mobile health technology solutions to tackle childhood obesity. |
| Collaborator Contribution | Direction and strategy |
| Impact | Multidiscplinary team comprising of NHS; public health; academia; smes; greatersport et al - to address the obesity epidemic in children and adults using innovative technologies. Final outputs from the workshops will be used to inform future technology development. CORGI team are currently applying for further funding from British Heart Foundation to develop mobile technology for children's healthy weight management. |
| Start Year | 2015 |
| Description | Collaboration with AstraZeneca Head of Advanced Analytics |
| Organisation | AstraZeneca |
| Department | Advanced Analytics Centre |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | HeRC Director presented a workshop at AstraZeneca Alderley Park about Health Data Science in June 2015, which resulted in their Global Head of Data Science now working 1 day per week in HeRC from February 2016 HeRC brings experience in technological innovation and data-intensive research to this collaboration. |
| Collaborator Contribution | Insight into the complex challenges of real-world medication |
| Impact | The aim of this collaboration is to advance patient health through better adherence and optimisation of medications. Techniques such as Endotype discovery modelling will facilitate a deeper understanding of health issues like asthma and psoriasis, enabling us to tailor treatments for these diseases. Current outputs from this collaboration include input into The Farr Institute's nationwide education and training programme to up-skill existing NHS Informaticians. |
| Start Year | 2015 |
| Description | Community Reporters project on senior citizens and health data |
| Organisation | Age UK |
| Department | Crossacres Resource Centre |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Sabine van der Veer applied for internal funding (HPPI Small Project Scheme) and was awarded £4862 for the project. She coordinated project activities, delivered workshops with senior citizens around the use of health data/technology and led on dissemination of the findings (website; conference abstract; seminar). |
| Collaborator Contribution | Salford ICT, Macc and Crossacres supported or delivered the community reporter training, recruitment of participants, editing and uploading of community reports onto Community Reporter website, and creating a compilation of community reports. MICRA supported promoting the project among their network, and will coordinate the seminar where findings will be presented. |
| Impact | - Abstract entitled 'Community Reports to capture older people's views on health data' (see Publications) accepted as oral presentation at the Informatics for Health conference (Manchester, 24-26 April) - Seminar entitled 'Using digital health technologies for ageing in community settings' to disseminate findings (see Engagement activities) - Salford Inspiring Communities Together plan to integrate health data technology training as part of their portfolio of community services (see Engagement activities) |
| Start Year | 2016 |
| Description | Community Reporters project on senior citizens and health data |
| Organisation | Inspiring Communities Together |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Sabine van der Veer applied for internal funding (HPPI Small Project Scheme) and was awarded £4862 for the project. She coordinated project activities, delivered workshops with senior citizens around the use of health data/technology and led on dissemination of the findings (website; conference abstract; seminar). |
| Collaborator Contribution | Salford ICT, Macc and Crossacres supported or delivered the community reporter training, recruitment of participants, editing and uploading of community reports onto Community Reporter website, and creating a compilation of community reports. MICRA supported promoting the project among their network, and will coordinate the seminar where findings will be presented. |
| Impact | - Abstract entitled 'Community Reports to capture older people's views on health data' (see Publications) accepted as oral presentation at the Informatics for Health conference (Manchester, 24-26 April) - Seminar entitled 'Using digital health technologies for ageing in community settings' to disseminate findings (see Engagement activities) - Salford Inspiring Communities Together plan to integrate health data technology training as part of their portfolio of community services (see Engagement activities) |
| Start Year | 2016 |
| Description | Community Reporters project on senior citizens and health data |
| Organisation | Manchester Community Central |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Sabine van der Veer applied for internal funding (HPPI Small Project Scheme) and was awarded £4862 for the project. She coordinated project activities, delivered workshops with senior citizens around the use of health data/technology and led on dissemination of the findings (website; conference abstract; seminar). |
| Collaborator Contribution | Salford ICT, Macc and Crossacres supported or delivered the community reporter training, recruitment of participants, editing and uploading of community reports onto Community Reporter website, and creating a compilation of community reports. MICRA supported promoting the project among their network, and will coordinate the seminar where findings will be presented. |
| Impact | - Abstract entitled 'Community Reports to capture older people's views on health data' (see Publications) accepted as oral presentation at the Informatics for Health conference (Manchester, 24-26 April) - Seminar entitled 'Using digital health technologies for ageing in community settings' to disseminate findings (see Engagement activities) - Salford Inspiring Communities Together plan to integrate health data technology training as part of their portfolio of community services (see Engagement activities) |
| Start Year | 2016 |
| Description | Community Reporters project on senior citizens and health data |
| Organisation | Manchester Institute for Collaborative Research on Ageing |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Sabine van der Veer applied for internal funding (HPPI Small Project Scheme) and was awarded £4862 for the project. She coordinated project activities, delivered workshops with senior citizens around the use of health data/technology and led on dissemination of the findings (website; conference abstract; seminar). |
| Collaborator Contribution | Salford ICT, Macc and Crossacres supported or delivered the community reporter training, recruitment of participants, editing and uploading of community reports onto Community Reporter website, and creating a compilation of community reports. MICRA supported promoting the project among their network, and will coordinate the seminar where findings will be presented. |
| Impact | - Abstract entitled 'Community Reports to capture older people's views on health data' (see Publications) accepted as oral presentation at the Informatics for Health conference (Manchester, 24-26 April) - Seminar entitled 'Using digital health technologies for ageing in community settings' to disseminate findings (see Engagement activities) - Salford Inspiring Communities Together plan to integrate health data technology training as part of their portfolio of community services (see Engagement activities) |
| Start Year | 2016 |
| Description | EPSRC Network for Mental Health Technologies: NewMind |
| Organisation | National Institute for Health Research |
| Department | MindTech Healthcare Technology Co-operative |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Chris Taylor and John Ainsworth have successfully received funding to lead (as Co-Is) this new network in partnership with MindTech HTC. Theme leads for Manchester include Chris Taylor, John Ainsworth, Patrick Gaydecki, Shon Lewis, Corinna Lovell and Ira Leroi. |
| Collaborator Contribution | 60 members across Industry and academia. The network includes collaborators in York, Lancaster, Philips Research UK, Janssen Healthcare Innovations, Intel |
| Impact | Working with researchers, clinicians, patients and industry, the project has developed a research roadmap, setting out target mental health outcomes, engineering and physical science research challenges, and an ethical and responsible innovation framework. This project has now also received a further 3 years of funding from NIHR. |
| Start Year | 2014 |
| Description | Exchange scheme with US Health Informaticians |
| Organisation | Harvard University |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | Farr @ HeRC has formalised its main axis of collaboration with US health informaticians in an exchange scheme with Harvard University and the i2b2 network. The aim is to create a replication pipeline for emerging findings, weeding out non-reproducible observational research pre-publication and homing in on important findings with a bigger collective denominator and more heterogeneity of populations/environments/observation processes. |
| Collaborator Contribution | Farr @ HeRC has formalised its main axis of collaboration with US health informaticians in an exchange scheme with Harvard University and the i2b2 network. The aim is to create a replication pipeline for emerging findings, weeding out non-reproducible observational research pre-publication and homing in on important findings with a bigger collective denominator and more heterogeneity of populations/environments/observation processes. |
| Impact | Harvard sent researchers to The University of Manchester for a two day workshop in September 2015 to shape and develop ideas with Manchester colleagues. Attendees have been invited to submit proposals based on the ideas developed in these workshops, the proposals will be assessed and one will be funded to visit Harvard to work the idea up to a full grant proposal. |
| Start Year | 2014 |
| Description | Exchange scheme with US Health Informaticians |
| Organisation | Informatics for Integrating Biology and the Bedside (i2b2) |
| Country | United States |
| Sector | Charity/Non Profit |
| PI Contribution | Farr @ HeRC has formalised its main axis of collaboration with US health informaticians in an exchange scheme with Harvard University and the i2b2 network. The aim is to create a replication pipeline for emerging findings, weeding out non-reproducible observational research pre-publication and homing in on important findings with a bigger collective denominator and more heterogeneity of populations/environments/observation processes. |
| Collaborator Contribution | Farr @ HeRC has formalised its main axis of collaboration with US health informaticians in an exchange scheme with Harvard University and the i2b2 network. The aim is to create a replication pipeline for emerging findings, weeding out non-reproducible observational research pre-publication and homing in on important findings with a bigger collective denominator and more heterogeneity of populations/environments/observation processes. |
| Impact | Harvard sent researchers to The University of Manchester for a two day workshop in September 2015 to shape and develop ideas with Manchester colleagues. Attendees have been invited to submit proposals based on the ideas developed in these workshops, the proposals will be assessed and one will be funded to visit Harvard to work the idea up to a full grant proposal. |
| Start Year | 2014 |
| Description | Farr Industry Forum: December 2013 Herc@Farr led the Farr Institute's Inaugural Industry Forum |
| Organisation | Farr Institute of Health Informatics Research |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The inaugural Farr Institute Industry forum was designed, managed, co-ordinated and hosted in Manchester by HeRC. This was attended by approximately 100 delegates across academia, the NHS, industry and the third sector, as well as all four Farr centre directors. |
| Collaborator Contribution | The event was held at The Landing @ Media City UK; sister Farr nodes supported and co-designed content. |
| Impact | Deepened and broadened engagement with Industry. |
| Start Year | 2013 |
| Description | Google Android Wear |
| Organisation | |
| Country | United States |
| Sector | Private |
| PI Contribution | Established new collaboration between University of Manchester and Google Android Wear. Co-designed a smartwatch app for self-reported pain and activity alongside passively collected activity data. Will be Google Android Wear's first health study with a view to ongoing collaboration. The study will be nested within Cloudy with a Chance of Pain |
| Collaborator Contribution | Developed partnership through direct contact with lead engineer at Google Android Wear, proposing the research study and partnership |
| Impact | Project is expected to launch in April 2017. Google providing 100 smartwatches and in kind contributions from software and hardware engineering |
| Start Year | 2016 |
| Description | Google Fit Research |
| Organisation | |
| Department | Google UK |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | UoM team provided scientific input to the design of a smartwatch application for health research studies. |
| Collaborator Contribution | Google developed the smartwatch data collection platform. |
| Impact | Publications about feasibility studies using smartwatches for health research |
| Start Year | 2018 |
| Description | HeRC eInfrastructure Developments |
| Organisation | MRC Dementias Platform UK |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Technical input to TRE infrastructure upgrades, sensing platform and eLab development and project management |
| Collaborator Contribution | Financial contribution to the upgrade of TRE, project management and input into platform developments from biological/disease perscpective |
| Impact | HeRC Trusted Research Environment infrastructure upgraded with additional investment from MRC CRI awards. - In partnership with Dementias Platform UK the HeRC TRE includes a sensing platform to collect data from wearable and mobile devices. - In partnership with the Manchester Stoller Biomarker Discovery Centre the HeRC TRE has developed an eLab platform data analytics on linked health record and proteomic data. |
| Start Year | 2014 |
| Description | HeRC eInfrastructure Developments |
| Organisation | University of Manchester |
| Department | Stoller Biomarker Discovery Centre |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Technical input to TRE infrastructure upgrades, sensing platform and eLab development and project management |
| Collaborator Contribution | Financial contribution to the upgrade of TRE, project management and input into platform developments from biological/disease perscpective |
| Impact | HeRC Trusted Research Environment infrastructure upgraded with additional investment from MRC CRI awards. - In partnership with Dementias Platform UK the HeRC TRE includes a sensing platform to collect data from wearable and mobile devices. - In partnership with the Manchester Stoller Biomarker Discovery Centre the HeRC TRE has developed an eLab platform data analytics on linked health record and proteomic data. |
| Start Year | 2014 |
| Description | Health Unlocked |
| Organisation | Health Unlocked |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Surveys within HU platform. Analysis of narratives within HU communities |
| Collaborator Contribution | Data provision and extension of their HealthGraph |
| Impact | No outputs to date |
| Start Year | 2016 |
| Description | Health Unlocked (Cloudy with a Chance of Pain) |
| Organisation | Health Unlocked |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Offer of writing up an analysis of the effectiveness of using Health Unlocked as a recruitment tool for research studies. |
| Collaborator Contribution | Provision of a social media community on Health Unlocked to support the recruitment and engagement of participants to Cloudy with a Chance of Pain. |
| Impact | 57 people recruited to Cloudy with a Chance of Pain through Health Unlocked. |
| Start Year | 2016 |
| Description | IMO-Salford Automation of Clinical Coding (ISACC) |
| Organisation | Intelligent Medical Objects |
| Country | United States |
| Sector | Private |
| PI Contribution | Goran Nenadic is the PI on the project and supervises the research. Sabine van der Veer and Zoher Kapacee are managing the project, including arranging contracts and ethical approval. |
| Collaborator Contribution | IMO delivers the software, provides technical support and funds part of the research activities. Salford Royal's IT department purchased and installed hardware, prepared the data for analysis and will coordinate the data processing. |
| Impact | No output yet, but IMO are organising a focus group at the Informatics for Health conference where this project will serve as an exemplar. |
| Start Year | 2015 |
| Description | IMO-Salford Automation of Clinical Coding (ISACC) |
| Organisation | Salford Royal NHS Foundation Trust |
| Department | Neuroscience Intensive Care Unit |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Goran Nenadic is the PI on the project and supervises the research. Sabine van der Veer and Zoher Kapacee are managing the project, including arranging contracts and ethical approval. |
| Collaborator Contribution | IMO delivers the software, provides technical support and funds part of the research activities. Salford Royal's IT department purchased and installed hardware, prepared the data for analysis and will coordinate the data processing. |
| Impact | No output yet, but IMO are organising a focus group at the Informatics for Health conference where this project will serve as an exemplar. |
| Start Year | 2015 |
| Description | Kidney Disease@Farr |
| Organisation | Farr Institute of Health Informatics Research |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Sabine van der Veer is co-leading the collaboration together with Corri Black (University of Aberdeen). We have organised two face-to-face meetings: one in Manchester (August 2016) and one Edinburgh (February 2017). We have had conversations with MRC in 2016 around potential for future programme funding, and what would be required to fulfil that potential. This has resulted in the collaboration being supported by 25K springboard funding from the Farr Institute. Sabine van der Veer is the PI on this grant and leads the two related research projects (replicating an AKI electronic phenotyping algorithm across regions; The UK data resource landscape as a platform for renal research). She is also supervising Heather Robinson, who is the PDRA from HeRC on the grant. |
| Collaborator Contribution | They are funding researchers to attend the meetings and run analyses on local data sources for specific projects. |
| Impact | - Further funding of 25,000 GBP as part of UK HIRN cross centre project grant (Farr, University of Edinburgh) - Abstract accepted for oral presentation entitled 'Assessing the robustness of an electronic phenotyping algorithm using EHR data to identify episodes of acute kidney injury across health care settings' at the Informatics for Health conference (Manchester, 24-26 April) |
| Start Year | 2015 |
| Description | Kidney Disease@Farr |
| Organisation | Farr Institute of Health Informatics Research |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Sabine van der Veer is co-leading the collaboration together with Corri Black (University of Aberdeen). We have organised two face-to-face meetings: one in Manchester (August 2016) and one Edinburgh (February 2017). We have had conversations with MRC in 2016 around potential for future programme funding, and what would be required to fulfil that potential. This has resulted in the collaboration being supported by 25K springboard funding from the Farr Institute. Sabine van der Veer is the PI on this grant and leads the two related research projects (replicating an AKI electronic phenotyping algorithm across regions; The UK data resource landscape as a platform for renal research). She is also supervising Heather Robinson, who is the PDRA from HeRC on the grant. |
| Collaborator Contribution | They are funding researchers to attend the meetings and run analyses on local data sources for specific projects. |
| Impact | - Further funding of 25,000 GBP as part of UK HIRN cross centre project grant (Farr, University of Edinburgh) - Abstract accepted for oral presentation entitled 'Assessing the robustness of an electronic phenotyping algorithm using EHR data to identify episodes of acute kidney injury across health care settings' at the Informatics for Health conference (Manchester, 24-26 April) |
| Start Year | 2015 |
| Description | Kidney Disease@Farr |
| Organisation | Farr Institute of Health Informatics Research |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Sabine van der Veer is co-leading the collaboration together with Corri Black (University of Aberdeen). We have organised two face-to-face meetings: one in Manchester (August 2016) and one Edinburgh (February 2017). We have had conversations with MRC in 2016 around potential for future programme funding, and what would be required to fulfil that potential. This has resulted in the collaboration being supported by 25K springboard funding from the Farr Institute. Sabine van der Veer is the PI on this grant and leads the two related research projects (replicating an AKI electronic phenotyping algorithm across regions; The UK data resource landscape as a platform for renal research). She is also supervising Heather Robinson, who is the PDRA from HeRC on the grant. |
| Collaborator Contribution | They are funding researchers to attend the meetings and run analyses on local data sources for specific projects. |
| Impact | - Further funding of 25,000 GBP as part of UK HIRN cross centre project grant (Farr, University of Edinburgh) - Abstract accepted for oral presentation entitled 'Assessing the robustness of an electronic phenotyping algorithm using EHR data to identify episodes of acute kidney injury across health care settings' at the Informatics for Health conference (Manchester, 24-26 April) |
| Start Year | 2015 |
| Description | Kidney Disease@Farr |
| Organisation | UK Renal Registry |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Sabine van der Veer is co-leading the collaboration together with Corri Black (University of Aberdeen). We have organised two face-to-face meetings: one in Manchester (August 2016) and one Edinburgh (February 2017). We have had conversations with MRC in 2016 around potential for future programme funding, and what would be required to fulfil that potential. This has resulted in the collaboration being supported by 25K springboard funding from the Farr Institute. Sabine van der Veer is the PI on this grant and leads the two related research projects (replicating an AKI electronic phenotyping algorithm across regions; The UK data resource landscape as a platform for renal research). She is also supervising Heather Robinson, who is the PDRA from HeRC on the grant. |
| Collaborator Contribution | They are funding researchers to attend the meetings and run analyses on local data sources for specific projects. |
| Impact | - Further funding of 25,000 GBP as part of UK HIRN cross centre project grant (Farr, University of Edinburgh) - Abstract accepted for oral presentation entitled 'Assessing the robustness of an electronic phenotyping algorithm using EHR data to identify episodes of acute kidney injury across health care settings' at the Informatics for Health conference (Manchester, 24-26 April) |
| Start Year | 2015 |
| Description | Kidney Disease@Farr |
| Organisation | University of Southampton |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Sabine van der Veer is co-leading the collaboration together with Corri Black (University of Aberdeen). We have organised two face-to-face meetings: one in Manchester (August 2016) and one Edinburgh (February 2017). We have had conversations with MRC in 2016 around potential for future programme funding, and what would be required to fulfil that potential. This has resulted in the collaboration being supported by 25K springboard funding from the Farr Institute. Sabine van der Veer is the PI on this grant and leads the two related research projects (replicating an AKI electronic phenotyping algorithm across regions; The UK data resource landscape as a platform for renal research). She is also supervising Heather Robinson, who is the PDRA from HeRC on the grant. |
| Collaborator Contribution | They are funding researchers to attend the meetings and run analyses on local data sources for specific projects. |
| Impact | - Further funding of 25,000 GBP as part of UK HIRN cross centre project grant (Farr, University of Edinburgh) - Abstract accepted for oral presentation entitled 'Assessing the robustness of an electronic phenotyping algorithm using EHR data to identify episodes of acute kidney injury across health care settings' at the Informatics for Health conference (Manchester, 24-26 April) |
| Start Year | 2015 |
| Description | Knee Osteoarthritis Longitudinal Activity and Pain (Koalap), a sub study nested within the Cloudy with a Chance of Pain study |
| Organisation | Aston University |
| Department | School of Life and Health Sciences |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Design of smartwatch activity and pain sub study. The University will also recruit participants to the study, organise their onboarding, deal with queries and actively engage with study users. UoM will analyse the data as part of the Cloudy with a Chance of Pain data analysis. Google will derive useful insights about the use of smartwatches and apps in research studies. |
| Collaborator Contribution | Aston University - advice on passive sensor data to be collected by the smartwatch in the study of activity and pain, help with analysis of data (2017). Google - provision of smartwatches on loan for 3 months. Smartwatches valued at £331 (retail price), providing 100. Provision of online questionnaire for participants to complete at the end of the study. |
| Impact | Too early to report as study is still in the planning stage, due to launch March 2017. |
| Start Year | 2016 |
| Description | Knee Osteoarthritis Longitudinal Activity and Pain (Koalap), a sub study nested within the Cloudy with a Chance of Pain study |
| Organisation | |
| Country | United States |
| Sector | Private |
| PI Contribution | Design of smartwatch activity and pain sub study. The University will also recruit participants to the study, organise their onboarding, deal with queries and actively engage with study users. UoM will analyse the data as part of the Cloudy with a Chance of Pain data analysis. Google will derive useful insights about the use of smartwatches and apps in research studies. |
| Collaborator Contribution | Aston University - advice on passive sensor data to be collected by the smartwatch in the study of activity and pain, help with analysis of data (2017). Google - provision of smartwatches on loan for 3 months. Smartwatches valued at £331 (retail price), providing 100. Provision of online questionnaire for participants to complete at the end of the study. |
| Impact | Too early to report as study is still in the planning stage, due to launch March 2017. |
| Start Year | 2016 |
| Description | Large Scale Citizen Science Project for physical activity promotion |
| Organisation | Nokia |
| Department | Withings |
| Country | France |
| Sector | Private |
| PI Contribution | As a result of the mature relationship developed between HeRC and Withings, a new project is being scoped and planned at present as a collaboration between Withings, The University of Manchester and ConnectedHhelath Cities. The aim is to conduct a citizen science project with mass participation across the North of England to understand how digital health can be used as an intervention to increase physical activity and lower heartrate. |
| Collaborator Contribution | Withings bring expertise in the digital health and mobile health sector. Agreements are confidential as to scope of involvmenet at present. |
| Impact | In progress |
| Start Year | 2016 |
| Description | Large Scale Citizen Science Project for physical activity promotion |
| Organisation | Nokia |
| Department | Withings |
| Country | France |
| Sector | Private |
| PI Contribution | As a result of the mature relationship developed between HeRC and Withings, a new project is being scoped and planned at present as a collaboration between Withings, The University of Manchester and ConnectedHhelath Cities. The aim is to conduct a citizen science project with mass participation across the North of England to understand how digital health can be used as an intervention to increase physical activity and lower heartrate. |
| Collaborator Contribution | Withings bring expertise in the digital health and mobile health sector. Agreements are confidential as to scope of involvmenet at present. |
| Impact | In progress |
| Start Year | 2016 |
| Description | Liverpool-Malawi PhD Partnership |
| Organisation | University of Malawi |
| Department | College of Medicine |
| Country | Malawi |
| Sector | Academic/University |
| PI Contribution | The allocation and co-supervision of 3 PhD Studentships within the ESRC NWDTC, to develop spatial statistical methods linked to public health applications in Malawi. These studentships will be co-supervised |
| Collaborator Contribution | Co-supervision of PhD students |
| Impact | None yet - first student should complete in 2016. The partnership is multi-disciplinary covering statistics, epidemiology and public health. |
| Start Year | 2013 |
| Description | MASK - towards an open source de-identification of clinical narrative |
| Organisation | Institute of Clinical and Evaluative Sciences (ICES) |
| Country | Canada |
| Sector | Academic/University |
| PI Contribution | We aimed to enhance ICES' existing rule-based de-identification software to make it contextually driven by applying Artificial Intelligence (AI). Based on the Manchester University de-identification framework for name entity recognition, three machine learning-based algorithms for name entity recognition were implemented: CRF, BiLSTM recurrent neural networks with GLoVe and ELMo word embeddings. The models were trained on three different types of ICES data: Laboratory results, Electronic Medical Record (EMR) and echocardiogram data. |
| Collaborator Contribution | The ICES team collaborated with computer scientists at the University of Manchester who had already published work in this area and Evenset, a Toronto-based software company. Evenset developed the user interface and the masking modules. |
| Impact | Papers submitted. Open source tools in preparation |
| Start Year | 2018 |
| Description | Machine Learning Seminar Meetings with The University of Sheffield |
| Organisation | University of Sheffield |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Periodic machine learning seminar meetings in conjunction with The University of Sheffield (Neil Lawrence) and The University of Manchester (Faculty of Medicine and Human Sciences (FMHS) and Faculty of Life Sciences (FLS)) started in May 2013, with an audience of clinicians from The University Hospital of South Manchester, and an additional audience of students from the various departments. Two thematic seminars have been held so far at both university venues ("Bayesian Networks", "Deep learning"). |
| Collaborator Contribution | Periodic machine learning seminar meetings in conjunction with The University of Sheffield (Neil Lawrence) and The University of Manchester (Faculty of Medicine and Human Sciences (FMHS) and Faculty of Life Sciences (FLS)) started in May 2013, with an audience of clinicians from The University Hospital of South Manchester, and an additional audience of students from the various departments. Two thematic seminars have been held so far at both university venues ("Bayesian Networks", "Deep learning") |
| Impact | Collaboration is ongoing with the joint organisation of the 3rd Machine Learning for Personalized Medicine summer school in September 2015, which was attended by over 70 delegates (with a number international). The HeRC Director presented a Keynote 'Discovering Subgroups of Disease with Model-based Machine Learning' |
| Start Year | 2013 |
| Description | NHS Testbed - LTCs Intervention Evaluation |
| Organisation | Heywood Middleton and Rochdale CCG |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | HeRc researchers are providing the evaluation component of this NHS test Bed award to GMAHSN / Heywood Middleton and Rochdale CCG with partners at MSD and Verily (formerly Google Life sciences). The project will pilot and evaluate to help healthcare professionals better identify and support patients at risk of long term conditions using the most advanced new predictive techniques. Ongoing planning of MSD footprint in Connected Health Cities - next stage at MSD HQ in New Jersey in April 2016 |
| Collaborator Contribution | Aim: to help healthcare professionals better identify and support patients at risk of long term conditions using the most advanced new predictive techniques.This testbed is being rolled out as a pilot in Heywood Middleton and Rochdale CCG whjho provide the business and stakeholder leadership with GPs, CCG et al; MSD are providng he hardware associated with the services (telehealth). Verily provide the algorithm based analytical risk stratification expertise which defines the risk scores assigned. It is the combination of these components and their implementation which HeRC Investigators (van Staa, Peek, Hassan) will evaluate throught the project lifecycle. A full time research assistant is being employed to undertake the evaluation. |
| Impact | This partnership is aimed to pilot and evlaute an intervention within the NS as part of NHS testbeds programme, with a view to national rollout. |
| Start Year | 2016 |
| Description | NHS Testbed - LTCs Intervention Evaluation |
| Organisation | Merck |
| Department | Merck Sharp and Dohme Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | HeRc researchers are providing the evaluation component of this NHS test Bed award to GMAHSN / Heywood Middleton and Rochdale CCG with partners at MSD and Verily (formerly Google Life sciences). The project will pilot and evaluate to help healthcare professionals better identify and support patients at risk of long term conditions using the most advanced new predictive techniques. Ongoing planning of MSD footprint in Connected Health Cities - next stage at MSD HQ in New Jersey in April 2016 |
| Collaborator Contribution | Aim: to help healthcare professionals better identify and support patients at risk of long term conditions using the most advanced new predictive techniques.This testbed is being rolled out as a pilot in Heywood Middleton and Rochdale CCG whjho provide the business and stakeholder leadership with GPs, CCG et al; MSD are providng he hardware associated with the services (telehealth). Verily provide the algorithm based analytical risk stratification expertise which defines the risk scores assigned. It is the combination of these components and their implementation which HeRC Investigators (van Staa, Peek, Hassan) will evaluate throught the project lifecycle. A full time research assistant is being employed to undertake the evaluation. |
| Impact | This partnership is aimed to pilot and evlaute an intervention within the NS as part of NHS testbeds programme, with a view to national rollout. |
| Start Year | 2016 |
| Description | NHS Testbed - LTCs Intervention Evaluation |
| Organisation | North West Coast Greater Manchester Academic Health Science Network |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | HeRc researchers are providing the evaluation component of this NHS test Bed award to GMAHSN / Heywood Middleton and Rochdale CCG with partners at MSD and Verily (formerly Google Life sciences). The project will pilot and evaluate to help healthcare professionals better identify and support patients at risk of long term conditions using the most advanced new predictive techniques. Ongoing planning of MSD footprint in Connected Health Cities - next stage at MSD HQ in New Jersey in April 2016 |
| Collaborator Contribution | Aim: to help healthcare professionals better identify and support patients at risk of long term conditions using the most advanced new predictive techniques.This testbed is being rolled out as a pilot in Heywood Middleton and Rochdale CCG whjho provide the business and stakeholder leadership with GPs, CCG et al; MSD are providng he hardware associated with the services (telehealth). Verily provide the algorithm based analytical risk stratification expertise which defines the risk scores assigned. It is the combination of these components and their implementation which HeRC Investigators (van Staa, Peek, Hassan) will evaluate throught the project lifecycle. A full time research assistant is being employed to undertake the evaluation. |
| Impact | This partnership is aimed to pilot and evlaute an intervention within the NS as part of NHS testbeds programme, with a view to national rollout. |
| Start Year | 2016 |
| Description | NHS Testbed - LTCs Intervention Evaluation |
| Organisation | Verily Life Sciences LLC |
| Country | United States |
| Sector | Private |
| PI Contribution | HeRc researchers are providing the evaluation component of this NHS test Bed award to GMAHSN / Heywood Middleton and Rochdale CCG with partners at MSD and Verily (formerly Google Life sciences). The project will pilot and evaluate to help healthcare professionals better identify and support patients at risk of long term conditions using the most advanced new predictive techniques. Ongoing planning of MSD footprint in Connected Health Cities - next stage at MSD HQ in New Jersey in April 2016 |
| Collaborator Contribution | Aim: to help healthcare professionals better identify and support patients at risk of long term conditions using the most advanced new predictive techniques.This testbed is being rolled out as a pilot in Heywood Middleton and Rochdale CCG whjho provide the business and stakeholder leadership with GPs, CCG et al; MSD are providng he hardware associated with the services (telehealth). Verily provide the algorithm based analytical risk stratification expertise which defines the risk scores assigned. It is the combination of these components and their implementation which HeRC Investigators (van Staa, Peek, Hassan) will evaluate throught the project lifecycle. A full time research assistant is being employed to undertake the evaluation. |
| Impact | This partnership is aimed to pilot and evlaute an intervention within the NS as part of NHS testbeds programme, with a view to national rollout. |
| Start Year | 2016 |
| Description | NeoEPOCH: Neonatal Electronic health record data for Point Of Care Health research and continuous incremental improvement in neonatal care |
| Organisation | Imperial College London |
| Department | Imperial College Trust |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Chris Gale was awarded the MRC Clinical Scientist Award for NeoEPOCH. The overarching aim of this fellowship is to enable the continual identification and resolution of uncertainties in neonatal care. it is intended that such a system will embed randomised point-of-care trials (PoCT) within routine care in a manner akin to the Medical Research Council funded "mega-trials" that were considered an integral component of paediatric cancer care and revolutionised the treatment of childhood leukaemia from the 1970's. It will be used to implement the WHEAT trial. This pilot trial which will enrol 500 premature babies at 20 sites in order to evaluate different feeding times around blood transfusion, testing the effects on necrotising enterocolitis. The neonatal disease registry (with routinely collected data) will be used to measure the outcomes. Farr @ North will support the introduction of and host the e-lab environment for this trial, facilitating reproducible and transparent handling of the data. |
| Collaborator Contribution | The overarching aim of this fellowship is to enable the continual identification and resolution of uncertainties in neonatal care. I intend that such a system will embed randomised point-of-care trials (PoCT) within routine care in a manner akin to the Medical Research Council funded "mega-trials" that were considered an integral component of paediatric cancer care and revolutionised the treatment of childhood leukaemia from the 1970's. To achieve this I need to realise four key objectives detailed below. 1. Demonstrate that it is both feasible and efficient to use Electronic Health Record (EHR) data for PoCT. Measurable objectives are to: 2. Secure public and health professional confidence in neonatal EHR data by addressing concerns about data quality and involving stakeholders (professionals and parents) in data collection and utilisation. Measurable objectives are to: 3. Secure parent and health professional trust in PoCT so that participation in Research Ethics Committee approved research is considered the default rather than the exception. 4. Develop the methodological skills, knowledge and collaborations to lead and manage a National Neonatal Clinical Improvement Unit built around the use of EHR data for PoCT. |
| Impact | We developed a protocol in collaboration with parents, for a comparative-effectiveness, randomised controlled trial comparing two widely used blood transfusion practices in preterm babies. We incorporated four approaches to improve recruitment and efficiency: i) point-of-care design using Electronic Patient Records for patient identification, randomisation and data acquisition, ii) short two-page information sheet; iii) explicit mention of the possibility of inclusion benefit; iv) opt-out consent process with enrollment as the default. With the support of the UK Health Research Authority, we submitted an identical protocol simultaneously to 12 UK REC. http://www.nihr.ac.uk/images/32%20Matthew%20Hyde%20Cat%202.pdf |
| Start Year | 2016 |
| Description | NeoEPOCH: Neonatal Electronic health record data for Point Of Care Health research and continuous incremental improvement in neonatal care |
| Organisation | University of Leicester |
| Department | Leicester Clinical Trials Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Chris Gale was awarded the MRC Clinical Scientist Award for NeoEPOCH. The overarching aim of this fellowship is to enable the continual identification and resolution of uncertainties in neonatal care. it is intended that such a system will embed randomised point-of-care trials (PoCT) within routine care in a manner akin to the Medical Research Council funded "mega-trials" that were considered an integral component of paediatric cancer care and revolutionised the treatment of childhood leukaemia from the 1970's. It will be used to implement the WHEAT trial. This pilot trial which will enrol 500 premature babies at 20 sites in order to evaluate different feeding times around blood transfusion, testing the effects on necrotising enterocolitis. The neonatal disease registry (with routinely collected data) will be used to measure the outcomes. Farr @ North will support the introduction of and host the e-lab environment for this trial, facilitating reproducible and transparent handling of the data. |
| Collaborator Contribution | The overarching aim of this fellowship is to enable the continual identification and resolution of uncertainties in neonatal care. I intend that such a system will embed randomised point-of-care trials (PoCT) within routine care in a manner akin to the Medical Research Council funded "mega-trials" that were considered an integral component of paediatric cancer care and revolutionised the treatment of childhood leukaemia from the 1970's. To achieve this I need to realise four key objectives detailed below. 1. Demonstrate that it is both feasible and efficient to use Electronic Health Record (EHR) data for PoCT. Measurable objectives are to: 2. Secure public and health professional confidence in neonatal EHR data by addressing concerns about data quality and involving stakeholders (professionals and parents) in data collection and utilisation. Measurable objectives are to: 3. Secure parent and health professional trust in PoCT so that participation in Research Ethics Committee approved research is considered the default rather than the exception. 4. Develop the methodological skills, knowledge and collaborations to lead and manage a National Neonatal Clinical Improvement Unit built around the use of EHR data for PoCT. |
| Impact | We developed a protocol in collaboration with parents, for a comparative-effectiveness, randomised controlled trial comparing two widely used blood transfusion practices in preterm babies. We incorporated four approaches to improve recruitment and efficiency: i) point-of-care design using Electronic Patient Records for patient identification, randomisation and data acquisition, ii) short two-page information sheet; iii) explicit mention of the possibility of inclusion benefit; iv) opt-out consent process with enrollment as the default. With the support of the UK Health Research Authority, we submitted an identical protocol simultaneously to 12 UK REC. http://www.nihr.ac.uk/images/32%20Matthew%20Hyde%20Cat%202.pdf |
| Start Year | 2016 |
| Description | Networking Workshop between Manchester and Digital Health Institute |
| Organisation | Farr Institute of Health Informatics Research |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Niels Peek; John Ainsworth ; Naomi Chandler (Bus Engagement) Kris Matykiewicz (Bus Engagement) Paul Jarvis (NWEH) Sarah Thew (GM_AHSN) Carmel Dickinson; Kathryn McCall; Matthew Rigby (Big Data Community; CH Ecosystem) Brendan Faulds COO, DHI. Knowledge and opportunity sharing. |
| Collaborator Contribution | Knowledge and opportunity sharing. |
| Impact | A number of connections strengthened or initiated; several follow ups arranged between attendees. Opportunities for cross-Farr collaborations enhanced. |
| Start Year | 2014 |
| Description | Networking Workshop between Manchester and Digital Health Institute |
| Organisation | University of Edinburgh |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Niels Peek; John Ainsworth ; Naomi Chandler (Bus Engagement) Kris Matykiewicz (Bus Engagement) Paul Jarvis (NWEH) Sarah Thew (GM_AHSN) Carmel Dickinson; Kathryn McCall; Matthew Rigby (Big Data Community; CH Ecosystem) Brendan Faulds COO, DHI. Knowledge and opportunity sharing. |
| Collaborator Contribution | Knowledge and opportunity sharing. |
| Impact | A number of connections strengthened or initiated; several follow ups arranged between attendees. Opportunities for cross-Farr collaborations enhanced. |
| Start Year | 2014 |
| Description | New MoU with NICE being written to refocus on digital |
| Organisation | National Institute for Health and Care Excellence (NICE) |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Iain Buchan wrote NICE into a draft of the MRC Institute site proposal; "UoM has a memorandum of understanding with NICE that is being expanded to focus on digital futures of trustworthy, actionable evidence." |
| Collaborator Contribution | Andrew Dillon, CEO of NICE, visited Prof Buchan on 17 February 2017 to discuss a new MoU to be written with NICE refocusing on Digital Agenda. |
| Impact | HeRC Director Iain Buchan is attending a dinner hosted by Professor Ian Greer, with attendance by Andrew Dillon of NICE with his colleagues and senior colleagues at UoM, on 3 April 2017 to further discuss the MoU. |
| Start Year | 2017 |
| Description | New smartphone based method to detect perinatal depression. |
| Organisation | University of Salford |
| Department | School of Health Sciences |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The HeRC Director ran a workshop at The University of Salford to envision a new smartphone based method to detect perinatal depression, aiding early intervention and targeting an identified need. The concept arose from the HeRC Director in an earlier meeting with the Dean for Health Sciences, in a move to involve The University of Salford in the HeRC network. |
| Collaborator Contribution | Engaged with the development of a new smart phone based detection method. |
| Impact | The preparation of grant applications by a grant writing team across Salford, Manchester and York. |
| Start Year | 2013 |
| Description | New studies with AstraZeneca, Servier and Janssen in planning stages |
| Organisation | AstraZeneca |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Iain Buchan hosted two large meetings with Janssen and HeRC/UoM colleagues, on 26 October 2016 and 20 February 2017 respectively, to discuss collaboration with Janssen. Janssen Research Collaborations Farr researchers (Tjeerd van Staa, Iain Buchan et al) have been instrumental in driving a strategic relationship between the Greater Manchester (GM) city region and Janssen plc, to develop a suite of industry funded research projects into Treatment Resistant Depression (TRD). These are aligned to the GM devolution agenda and include digital health, informatics and clinical trials - details remain subject to signed confidentiality agreements at present. Workshops and focused meetings have now led to a stage of more defined programme planning for 2017 involved a multi-disciplinary team, including clinical psychology (Sandra Bucci), psychiatry (Bill Deakin, Shon Lewis), informaticians and trialists (Buchan, Van staa) and software engineers (Matt Machin, Pauline Whelan). |
| Collaborator Contribution | Nigel Hughes, Scientific Director, RMEDS (Real World Evidence, Medical Affairs, Established Products, Statistics) Quantitative Sciences (Janssen Research & Development), raised an opportunity to investigate a precision medicine approach over the longitudinal course of mental health patients' experience further in a pilot study, incorporating a post-doc placement, leading to larger-scale study and potential grant application would be a possible collaboration point between Janssen and University of Manchester/NHS Mental Health Services, and will be a discussion point for early phase funding and collaboration Peter Hecht, SGG DMD Coordination Team, Sanofi, has arranged to speak with Iain Buchan regarding a "Brainstorming Workshop" on future healthcare solutions in the area of Diabetes and Metabolic Disorders, call arranged for 6 March 2017. This initiative is driven out of the Innovative Medicine Initiative Strategic Governing Group Diabetes / Metabolic Disorders (SGG DMD) - consisting of senior R&D Diabetes executives from AstraZeneca, Boehringer Ingelheim, GSK, JnJ, Lilly, Novartis, Novo, Pfizer, Servier, Sanofi as well as Ellegaard, SomaLogic and representatives from the IMI Scientific Committee and the European Commission. |
| Impact | Janssen and UoM (at 20 Feb meeting) agreed Tjeerd van Staa would work on refining the current concept paper, and Sandra Bucci and Shôn Lewis would discuss with colleagues further. Nigel Hughes will continue to follow up with Therapeutic Area colleagues, as well as those working on specialised areas, such as digital biomarkers within Janssen |
| Start Year | 2015 |
| Description | New studies with AstraZeneca, Servier and Janssen in planning stages |
| Organisation | Janssen Research & Development |
| Country | Global |
| Sector | Private |
| PI Contribution | Iain Buchan hosted two large meetings with Janssen and HeRC/UoM colleagues, on 26 October 2016 and 20 February 2017 respectively, to discuss collaboration with Janssen. Janssen Research Collaborations Farr researchers (Tjeerd van Staa, Iain Buchan et al) have been instrumental in driving a strategic relationship between the Greater Manchester (GM) city region and Janssen plc, to develop a suite of industry funded research projects into Treatment Resistant Depression (TRD). These are aligned to the GM devolution agenda and include digital health, informatics and clinical trials - details remain subject to signed confidentiality agreements at present. Workshops and focused meetings have now led to a stage of more defined programme planning for 2017 involved a multi-disciplinary team, including clinical psychology (Sandra Bucci), psychiatry (Bill Deakin, Shon Lewis), informaticians and trialists (Buchan, Van staa) and software engineers (Matt Machin, Pauline Whelan). |
| Collaborator Contribution | Nigel Hughes, Scientific Director, RMEDS (Real World Evidence, Medical Affairs, Established Products, Statistics) Quantitative Sciences (Janssen Research & Development), raised an opportunity to investigate a precision medicine approach over the longitudinal course of mental health patients' experience further in a pilot study, incorporating a post-doc placement, leading to larger-scale study and potential grant application would be a possible collaboration point between Janssen and University of Manchester/NHS Mental Health Services, and will be a discussion point for early phase funding and collaboration Peter Hecht, SGG DMD Coordination Team, Sanofi, has arranged to speak with Iain Buchan regarding a "Brainstorming Workshop" on future healthcare solutions in the area of Diabetes and Metabolic Disorders, call arranged for 6 March 2017. This initiative is driven out of the Innovative Medicine Initiative Strategic Governing Group Diabetes / Metabolic Disorders (SGG DMD) - consisting of senior R&D Diabetes executives from AstraZeneca, Boehringer Ingelheim, GSK, JnJ, Lilly, Novartis, Novo, Pfizer, Servier, Sanofi as well as Ellegaard, SomaLogic and representatives from the IMI Scientific Committee and the European Commission. |
| Impact | Janssen and UoM (at 20 Feb meeting) agreed Tjeerd van Staa would work on refining the current concept paper, and Sandra Bucci and Shôn Lewis would discuss with colleagues further. Nigel Hughes will continue to follow up with Therapeutic Area colleagues, as well as those working on specialised areas, such as digital biomarkers within Janssen |
| Start Year | 2015 |
| Description | New studies with AstraZeneca, Servier and Janssen in planning stages |
| Organisation | Servier Laboratories |
| Country | France |
| Sector | Private |
| PI Contribution | Iain Buchan hosted two large meetings with Janssen and HeRC/UoM colleagues, on 26 October 2016 and 20 February 2017 respectively, to discuss collaboration with Janssen. Janssen Research Collaborations Farr researchers (Tjeerd van Staa, Iain Buchan et al) have been instrumental in driving a strategic relationship between the Greater Manchester (GM) city region and Janssen plc, to develop a suite of industry funded research projects into Treatment Resistant Depression (TRD). These are aligned to the GM devolution agenda and include digital health, informatics and clinical trials - details remain subject to signed confidentiality agreements at present. Workshops and focused meetings have now led to a stage of more defined programme planning for 2017 involved a multi-disciplinary team, including clinical psychology (Sandra Bucci), psychiatry (Bill Deakin, Shon Lewis), informaticians and trialists (Buchan, Van staa) and software engineers (Matt Machin, Pauline Whelan). |
| Collaborator Contribution | Nigel Hughes, Scientific Director, RMEDS (Real World Evidence, Medical Affairs, Established Products, Statistics) Quantitative Sciences (Janssen Research & Development), raised an opportunity to investigate a precision medicine approach over the longitudinal course of mental health patients' experience further in a pilot study, incorporating a post-doc placement, leading to larger-scale study and potential grant application would be a possible collaboration point between Janssen and University of Manchester/NHS Mental Health Services, and will be a discussion point for early phase funding and collaboration Peter Hecht, SGG DMD Coordination Team, Sanofi, has arranged to speak with Iain Buchan regarding a "Brainstorming Workshop" on future healthcare solutions in the area of Diabetes and Metabolic Disorders, call arranged for 6 March 2017. This initiative is driven out of the Innovative Medicine Initiative Strategic Governing Group Diabetes / Metabolic Disorders (SGG DMD) - consisting of senior R&D Diabetes executives from AstraZeneca, Boehringer Ingelheim, GSK, JnJ, Lilly, Novartis, Novo, Pfizer, Servier, Sanofi as well as Ellegaard, SomaLogic and representatives from the IMI Scientific Committee and the European Commission. |
| Impact | Janssen and UoM (at 20 Feb meeting) agreed Tjeerd van Staa would work on refining the current concept paper, and Sandra Bucci and Shôn Lewis would discuss with colleagues further. Nigel Hughes will continue to follow up with Therapeutic Area colleagues, as well as those working on specialised areas, such as digital biomarkers within Janssen |
| Start Year | 2015 |
| Description | Ongoing collaboration with The University of Bradford |
| Organisation | University of Bradford |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | John Wright and Mohammed Mohammed have been leading projects at The University of Bradford in close collaboration with HeRC. The University of Bradford recently led a successful £12m bid to establish a University Enterprise Zone in the city (http://www.bradford.ac.uk/research-and-business/news/bradford-hosts-12-million-programme.php). As lead for Digital Health, the association with HeRC was highlighted as a key milestone. |
| Collaborator Contribution | The University of Bradford has continued to contribute to the HeRC portfolio in the form of joint publications and successful further funding applications. As a result of this each of the HeRC partner institutions have agreed that The University of Bradford should join HeRC as a partner. The addition of the University of Bradford as an official HeRC partner is currently in process. |
| Impact | HeRC is in the process of adding The University of Bradford as an official partner. To this end joint outputs include a number of publications, funding applications and ongoing collaborative research projects. The Born in Bradford 5th Annual Conference was attending by a number of HeRC researchers and students. The conference and PhD student poster session demonstrated how the Born in Bradford data is being used and applied for patient and public benefit. |
| Start Year | 2014 |
| Description | PHErCoOl: Distributed Processing of High-Throughput Sequencing Data via De Brujin Graphs |
| Organisation | Roma Tre University |
| Country | Italy |
| Sector | Academic/University |
| PI Contribution | We developed a new methodology for error correction of next-generation sequencing data. The methodology has been initially implemented and released as open-source (GNU-GPL) in java, and then we wrote a cost-free grant with the University of Roma TRE to obtain COMPUTATIONAL resources to improve the method and its implementation using C++ and advanced parallelisation techniques. The grant has been awarded by the Italian consortium CINECA who provided free subscription to their high-performance computing cluster. |
| Collaborator Contribution | University of Roma TRE has developed the code porting into C++, new optimised internal algorithms and new implementation |
| Impact | Publication in IEEE/CBMS: http://plm.dia.uniroma3.it/milicchio/wp-content/uploads/2014/05/CBMS2014.pdf |
| Start Year | 2013 |
| Description | Processing patient feedback data |
| Organisation | NHS England |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Discussion on collaboration for processing patient feedback data (Friends and Family test). |
| Collaborator Contribution | Requirements and understanding of the needs for processing patient feedback data. |
| Impact | Discussions for future funding and knowledge transfer. |
| Start Year | 2018 |
| Description | Regional Partnerships: N8, AHSN, NHSA |
| Organisation | Academic Health Science Network for the North East and North Cumbria |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | The HeRC Deputy Director is leading on eInfrastructure as part of the MRC Capital Investment in the Farr Institute for Health Informatics Research. The result is an agreement between HeRC, the four Northern AHSNs, N8 Universities and the NHSA to work in partnership towards regional informatics solutions to federate routinely captured health data records. |
| Collaborator Contribution | Engagement with HeRC and other partners to drive regional informatics solutions to federate routinely captured health data records. |
| Impact | Building on previous work with the N8 Universities, the four Northern AHSN and the NHSA has led to the following initiatives: a. Health North - a far reaching programme to create learning health systems across the North of England. A £20m pilot project, Connected Health Cities, was funded by Dept of Health and began in January 2016 b. In partnership with the NHSA the deployment of FARSITE system for searching primary care data, continues to be rolled out across the four Northern AHSNs. |
| Start Year | 2013 |
| Description | Regional Partnerships: N8, AHSN, NHSA |
| Organisation | N8 Universities |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The HeRC Deputy Director is leading on eInfrastructure as part of the MRC Capital Investment in the Farr Institute for Health Informatics Research. The result is an agreement between HeRC, the four Northern AHSNs, N8 Universities and the NHSA to work in partnership towards regional informatics solutions to federate routinely captured health data records. |
| Collaborator Contribution | Engagement with HeRC and other partners to drive regional informatics solutions to federate routinely captured health data records. |
| Impact | Building on previous work with the N8 Universities, the four Northern AHSN and the NHSA has led to the following initiatives: a. Health North - a far reaching programme to create learning health systems across the North of England. A £20m pilot project, Connected Health Cities, was funded by Dept of Health and began in January 2016 b. In partnership with the NHSA the deployment of FARSITE system for searching primary care data, continues to be rolled out across the four Northern AHSNs. |
| Start Year | 2013 |
| Description | Regional Partnerships: N8, AHSN, NHSA |
| Organisation | North West Coast Greater Manchester Academic Health Science Network |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The HeRC Deputy Director is leading on eInfrastructure as part of the MRC Capital Investment in the Farr Institute for Health Informatics Research. The result is an agreement between HeRC, the four Northern AHSNs, N8 Universities and the NHSA to work in partnership towards regional informatics solutions to federate routinely captured health data records. |
| Collaborator Contribution | Engagement with HeRC and other partners to drive regional informatics solutions to federate routinely captured health data records. |
| Impact | Building on previous work with the N8 Universities, the four Northern AHSN and the NHSA has led to the following initiatives: a. Health North - a far reaching programme to create learning health systems across the North of England. A £20m pilot project, Connected Health Cities, was funded by Dept of Health and began in January 2016 b. In partnership with the NHSA the deployment of FARSITE system for searching primary care data, continues to be rolled out across the four Northern AHSNs. |
| Start Year | 2013 |
| Description | Regional Partnerships: N8, AHSN, NHSA |
| Organisation | Northern Health Science Alliance Ltd (NHSA) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The HeRC Deputy Director is leading on eInfrastructure as part of the MRC Capital Investment in the Farr Institute for Health Informatics Research. The result is an agreement between HeRC, the four Northern AHSNs, N8 Universities and the NHSA to work in partnership towards regional informatics solutions to federate routinely captured health data records. |
| Collaborator Contribution | Engagement with HeRC and other partners to drive regional informatics solutions to federate routinely captured health data records. |
| Impact | Building on previous work with the N8 Universities, the four Northern AHSN and the NHSA has led to the following initiatives: a. Health North - a far reaching programme to create learning health systems across the North of England. A £20m pilot project, Connected Health Cities, was funded by Dept of Health and began in January 2016 b. In partnership with the NHSA the deployment of FARSITE system for searching primary care data, continues to be rolled out across the four Northern AHSNs. |
| Start Year | 2013 |
| Description | Regional Partnerships: N8, AHSN, NHSA |
| Organisation | University of Manchester |
| Department | Manchester Academic Health Science Centre |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The HeRC Deputy Director is leading on eInfrastructure as part of the MRC Capital Investment in the Farr Institute for Health Informatics Research. The result is an agreement between HeRC, the four Northern AHSNs, N8 Universities and the NHSA to work in partnership towards regional informatics solutions to federate routinely captured health data records. |
| Collaborator Contribution | Engagement with HeRC and other partners to drive regional informatics solutions to federate routinely captured health data records. |
| Impact | Building on previous work with the N8 Universities, the four Northern AHSN and the NHSA has led to the following initiatives: a. Health North - a far reaching programme to create learning health systems across the North of England. A £20m pilot project, Connected Health Cities, was funded by Dept of Health and began in January 2016 b. In partnership with the NHSA the deployment of FARSITE system for searching primary care data, continues to be rolled out across the four Northern AHSNs. |
| Start Year | 2013 |
| Description | Regional Partnerships: N8, AHSN, NHSA |
| Organisation | Yorkshire and Humber Academic Health Science Network |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | The HeRC Deputy Director is leading on eInfrastructure as part of the MRC Capital Investment in the Farr Institute for Health Informatics Research. The result is an agreement between HeRC, the four Northern AHSNs, N8 Universities and the NHSA to work in partnership towards regional informatics solutions to federate routinely captured health data records. |
| Collaborator Contribution | Engagement with HeRC and other partners to drive regional informatics solutions to federate routinely captured health data records. |
| Impact | Building on previous work with the N8 Universities, the four Northern AHSN and the NHSA has led to the following initiatives: a. Health North - a far reaching programme to create learning health systems across the North of England. A £20m pilot project, Connected Health Cities, was funded by Dept of Health and began in January 2016 b. In partnership with the NHSA the deployment of FARSITE system for searching primary care data, continues to be rolled out across the four Northern AHSNs. |
| Start Year | 2013 |
| Description | Research Object |
| Organisation | researchobject.org |
| Sector | Charity/Non Profit |
| PI Contribution | researchobject.org is a grass roots community to develop and disseminate Research Objects, their concept, adoption, and other latest developments. It was established by Prof Goble's e-Science group and is now a global community with academic and commercial members. |
| Collaborator Contribution | The community have developed specifications, implementations and run a series of international workshops. |
| Impact | Specifications of Research Objects, including RO-Crate http://www.researchobject.org/2019-11-15-ro-crate-1-0/ funding from Elsevier, incorporation into data repositories (DataVerse, Mendeley Data) and the NIH Data Commons Core to the development of the workflow collaboratory for the EOSCLife project (European Open Science Cloud Life). A component of the EU EOSC FAIR Digital Object Framework Multidisciplinary - chiefly the life sciences, biodiversity and computer science |
| Start Year | 2013 |
| Description | Second phase of works with LumiraDx, IBM and Ernst & Young on Datawell |
| Organisation | Ernst and Young LLP |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Iain Buchan met with Sumit Nagpal, Co-Founder LumiraDx and Board Member (Elect) HIMSS North America, during a business trip to Boston, USA on Iain Buchan hosted a visit by Sumit Nagpal on 18 August 2016 during which collaborations were discussed for LumiraDx to supply the new DataWell system which could be a way connect T-MACS to faster troponin testing. Dr Rick Body, met with Nigel Lindner and Jerry McAleer from LumiraDx to discuss the DataWell project and the LumiraDx troponin assay (September 2015) outcome of which was that he hoped his team could work with LumiraDx to design some innovative ways to deliver healthcare. Iain Buchan and John Ainsworth have met with Mike Broomhead, Industry Architect for Healthcare & Life Sciences, at IBM Watson to discuss how IBM can add value to Connected Health Cities and 'next gen' potential and to bring give-back to relevant communities and look how to apply first-of-a-kind such as research work to be 'operationally' viable. |
| Collaborator Contribution | LumiraDx to partner with HeRC on Informatics for Health 2017 Conference 24-26 April 2017 and exhibit at the conference. Sumit Nagpal asked to contribute to article entitled 'Can Technology Save the NHS?' for PC Pro, co-authored by Iain Buchan, and also asked to comment on a second article on data driven healthcare, which James Foster (Apple watch designer) is also asked to comment on. Sumit Nagpal contributed to a proposal to George Freeman, MP, entitled 'LumiraDx: Better Outcomes at Scale via Digital Engagement of Individuals and Their Care Teams' which proposed to Build on Datawell's Remit Across 2.9+ Million Individuals in Northern Connected Health Cities. John Farenden - Ernst & Young sits on the GM-CHC Steering Group. GM AHSN procured a consortia of three experienced international companies to develop DataWell with them. The new DataWell technology comes from US healthcare systems specialists LumiraDx; the task of linking DataWell into existing NHS and Social Care information systems is being handled by IBM, and EY (formerly Ernst & Young) is providing change management services across the project. These vendors provide some of the capabilities for DataWell but DataWell in a pan GM innovation organisation. It's partners and tools are not the DataWell programme in the same way any individual is not their phone or mobile device. |
| Impact | Further meetings with Iain Buchan and Sumit Nagpal are ongoing as and when they can meet/talk. Dr Rick Body hoped his team could work with LumiraDx to design some innovative ways to deliver healthcare. John Ainsworth met with Mike Broomhead, IBM Watson,and outcomes were: 1. Possibility of running a Watson Health pilot on Datawell for CHC. 2. Possible partner for National Academy proposal - |
| Start Year | 2016 |
| Description | Second phase of works with LumiraDx, IBM and Ernst & Young on Datawell |
| Organisation | IBM |
| Department | IBM UK Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Iain Buchan met with Sumit Nagpal, Co-Founder LumiraDx and Board Member (Elect) HIMSS North America, during a business trip to Boston, USA on Iain Buchan hosted a visit by Sumit Nagpal on 18 August 2016 during which collaborations were discussed for LumiraDx to supply the new DataWell system which could be a way connect T-MACS to faster troponin testing. Dr Rick Body, met with Nigel Lindner and Jerry McAleer from LumiraDx to discuss the DataWell project and the LumiraDx troponin assay (September 2015) outcome of which was that he hoped his team could work with LumiraDx to design some innovative ways to deliver healthcare. Iain Buchan and John Ainsworth have met with Mike Broomhead, Industry Architect for Healthcare & Life Sciences, at IBM Watson to discuss how IBM can add value to Connected Health Cities and 'next gen' potential and to bring give-back to relevant communities and look how to apply first-of-a-kind such as research work to be 'operationally' viable. |
| Collaborator Contribution | LumiraDx to partner with HeRC on Informatics for Health 2017 Conference 24-26 April 2017 and exhibit at the conference. Sumit Nagpal asked to contribute to article entitled 'Can Technology Save the NHS?' for PC Pro, co-authored by Iain Buchan, and also asked to comment on a second article on data driven healthcare, which James Foster (Apple watch designer) is also asked to comment on. Sumit Nagpal contributed to a proposal to George Freeman, MP, entitled 'LumiraDx: Better Outcomes at Scale via Digital Engagement of Individuals and Their Care Teams' which proposed to Build on Datawell's Remit Across 2.9+ Million Individuals in Northern Connected Health Cities. John Farenden - Ernst & Young sits on the GM-CHC Steering Group. GM AHSN procured a consortia of three experienced international companies to develop DataWell with them. The new DataWell technology comes from US healthcare systems specialists LumiraDx; the task of linking DataWell into existing NHS and Social Care information systems is being handled by IBM, and EY (formerly Ernst & Young) is providing change management services across the project. These vendors provide some of the capabilities for DataWell but DataWell in a pan GM innovation organisation. It's partners and tools are not the DataWell programme in the same way any individual is not their phone or mobile device. |
| Impact | Further meetings with Iain Buchan and Sumit Nagpal are ongoing as and when they can meet/talk. Dr Rick Body hoped his team could work with LumiraDx to design some innovative ways to deliver healthcare. John Ainsworth met with Mike Broomhead, IBM Watson,and outcomes were: 1. Possibility of running a Watson Health pilot on Datawell for CHC. 2. Possible partner for National Academy proposal - |
| Start Year | 2016 |
| Description | Second phase of works with LumiraDx, IBM and Ernst & Young on Datawell |
| Organisation | LumiraDx |
| Country | United States |
| Sector | Private |
| PI Contribution | Iain Buchan met with Sumit Nagpal, Co-Founder LumiraDx and Board Member (Elect) HIMSS North America, during a business trip to Boston, USA on Iain Buchan hosted a visit by Sumit Nagpal on 18 August 2016 during which collaborations were discussed for LumiraDx to supply the new DataWell system which could be a way connect T-MACS to faster troponin testing. Dr Rick Body, met with Nigel Lindner and Jerry McAleer from LumiraDx to discuss the DataWell project and the LumiraDx troponin assay (September 2015) outcome of which was that he hoped his team could work with LumiraDx to design some innovative ways to deliver healthcare. Iain Buchan and John Ainsworth have met with Mike Broomhead, Industry Architect for Healthcare & Life Sciences, at IBM Watson to discuss how IBM can add value to Connected Health Cities and 'next gen' potential and to bring give-back to relevant communities and look how to apply first-of-a-kind such as research work to be 'operationally' viable. |
| Collaborator Contribution | LumiraDx to partner with HeRC on Informatics for Health 2017 Conference 24-26 April 2017 and exhibit at the conference. Sumit Nagpal asked to contribute to article entitled 'Can Technology Save the NHS?' for PC Pro, co-authored by Iain Buchan, and also asked to comment on a second article on data driven healthcare, which James Foster (Apple watch designer) is also asked to comment on. Sumit Nagpal contributed to a proposal to George Freeman, MP, entitled 'LumiraDx: Better Outcomes at Scale via Digital Engagement of Individuals and Their Care Teams' which proposed to Build on Datawell's Remit Across 2.9+ Million Individuals in Northern Connected Health Cities. John Farenden - Ernst & Young sits on the GM-CHC Steering Group. GM AHSN procured a consortia of three experienced international companies to develop DataWell with them. The new DataWell technology comes from US healthcare systems specialists LumiraDx; the task of linking DataWell into existing NHS and Social Care information systems is being handled by IBM, and EY (formerly Ernst & Young) is providing change management services across the project. These vendors provide some of the capabilities for DataWell but DataWell in a pan GM innovation organisation. It's partners and tools are not the DataWell programme in the same way any individual is not their phone or mobile device. |
| Impact | Further meetings with Iain Buchan and Sumit Nagpal are ongoing as and when they can meet/talk. Dr Rick Body hoped his team could work with LumiraDx to design some innovative ways to deliver healthcare. John Ainsworth met with Mike Broomhead, IBM Watson,and outcomes were: 1. Possibility of running a Watson Health pilot on Datawell for CHC. 2. Possible partner for National Academy proposal - |
| Start Year | 2016 |
| Description | Statistical modelling of HIV/AIDS |
| Organisation | International Foundation for Infectious Diseases and Health |
| Country | Italy |
| Sector | Academic/University |
| PI Contribution | Provision of expertise in statistics and machine learning in the HIV/AIDS field. |
| Collaborator Contribution | Provision of access to nation-wide cohort data on HIV. Availability to host students for exchange/visiting programs. |
| Impact | The production of joint study designs on HIV/AIDS epidemiology modelling, writing of scientific studies, conference presentations, etc. |
| Start Year | 2013 |
| Description | The CREW consortium |
| Organisation | University of Wisconsin-Madison |
| Country | United States |
| Sector | Academic/University |
| PI Contribution | We have created conditions that will facilitate data sharing with the consortium of 12 US-based birth cohorts (CREW). NIH has just announced that CREW were awarded funding through the Environmental influences on Child Health Outcomes (ECHO) programme, and CREW will utilise our UK STELAR knowledge management platform (eLab). This will provide a worldwide platform to help solve the global problem of asthma. Our flexible platform will be able to accommodate other cohorts and disease outcomes in future |
| Collaborator Contribution | The National Institutes of Health (NIH) has awarded the University of Wisconsin School of Medicine and Public Health a two-year, $15 million grant to establish and oversee the Children's Respiratory Research and Environment Workgroup (CREW) - a national consortium of 14 institutions that will study how genetics interact with environmental exposures during the prenatal and early childhood years to cause specific subtypes of childhood asthma. |
| Impact | We have created conditions that will facilitate data sharing with the consortium of 12 US-based birth cohorts. |
| Start Year | 2016 |
| Description | The Health and Employment After Fifty (HEAF) study |
| Organisation | University of Southampton |
| Department | MRC Lifecourse Epidemiology Unit |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Engaged in design and analysis of study |
| Collaborator Contribution | The need in many countries to work longer raises important questions concerning the health risks and benefits of extended working life, its feasibility in those with problems of ageing, and how best to support and maximize the well-being of older workers. The HEAF study aims to address these questions, and to identify the main drivers of work participation and job loss at older ages as possible targets for intervention. HEAF is a prospective cohort study of older people drawn from the patient registers of 24 English general practices which contribute data to a primary care research database (the CPRD). Subjects complete annual questionnaires concerning their health, work status, perceptions about work, retirement and other factors, including changes over time; further health data will come from their own medical files through record linkage. A 5 year follow-up is planned initially. Core funders Arthritis Research UK Medical Research Council ESRCThe Health and Employment After Fifty (HEAF) study |
| Impact | BMC Public Health. 2015 Oct 19;15:1071. doi: 10.1186/s12889-015-2396-8. Health and Employment after Fifty (HEAF): a new prospective cohort study. Palmer KT, Walker-Bone K, Harris EC, Linaker C, D'Angelo S, Sayer AA, Gale CR, Evandrou M, van Staa T, Cooper C, Coggon D |
| Start Year | 2014 |
| Description | The Office for Creative Research |
| Organisation | The Office for Creative Research (OCR) |
| Country | United States |
| Sector | Private |
| PI Contribution | Established connection with OCR in 2015 to explore opportunities for collaboration around Cloudy with a Chance of Pain and implementation of Dynamic Consent interface |
| Collaborator Contribution | Developing data visualisations and citizen science project |
| Impact | No outputs yet |
| Start Year | 2015 |
| Description | Transforming Participation in Chronic Kidney Disease (TP-CKD) |
| Organisation | British Kidney Patient Association |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Sabine van der Veer is leading the Measurement Workstream., which is the group advising NHS England on introducing routine collection of patient-reported outcomes in renal services. She is also a member of the TP-CKD programme board. Van der Veer attends quarterly Board meetings, and organises frequent meetings with the members of her Workstream. |
| Collaborator Contribution | NHS England is funding this national programme, including resources for programme coordination, facilitating activities in the participating renal units, and for face-to-face meetings with the Programme Board and for Workstreams. The UK Renal Registry coordinates data collection and analysis. |
| Impact | - Invited lecture at the 9th UK Annual Dialysis conference (Manchester, Sept 2016) - Invited lecture at the International Renal Epidemiology seminar (Paris, Sept 2016) - Chairing CME session entitled 'Including the patient perspective in renal care' at European Renal Association congress (May 2016) |
| Start Year | 2015 |
| Description | Transforming Participation in Chronic Kidney Disease (TP-CKD) |
| Organisation | NHS England |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | Sabine van der Veer is leading the Measurement Workstream., which is the group advising NHS England on introducing routine collection of patient-reported outcomes in renal services. She is also a member of the TP-CKD programme board. Van der Veer attends quarterly Board meetings, and organises frequent meetings with the members of her Workstream. |
| Collaborator Contribution | NHS England is funding this national programme, including resources for programme coordination, facilitating activities in the participating renal units, and for face-to-face meetings with the Programme Board and for Workstreams. The UK Renal Registry coordinates data collection and analysis. |
| Impact | - Invited lecture at the 9th UK Annual Dialysis conference (Manchester, Sept 2016) - Invited lecture at the International Renal Epidemiology seminar (Paris, Sept 2016) - Chairing CME session entitled 'Including the patient perspective in renal care' at European Renal Association congress (May 2016) |
| Start Year | 2015 |
| Description | Transforming Participation in Chronic Kidney Disease (TP-CKD) |
| Organisation | UK Renal Registry |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | Sabine van der Veer is leading the Measurement Workstream., which is the group advising NHS England on introducing routine collection of patient-reported outcomes in renal services. She is also a member of the TP-CKD programme board. Van der Veer attends quarterly Board meetings, and organises frequent meetings with the members of her Workstream. |
| Collaborator Contribution | NHS England is funding this national programme, including resources for programme coordination, facilitating activities in the participating renal units, and for face-to-face meetings with the Programme Board and for Workstreams. The UK Renal Registry coordinates data collection and analysis. |
| Impact | - Invited lecture at the 9th UK Annual Dialysis conference (Manchester, Sept 2016) - Invited lecture at the International Renal Epidemiology seminar (Paris, Sept 2016) - Chairing CME session entitled 'Including the patient perspective in renal care' at European Renal Association congress (May 2016) |
| Start Year | 2015 |
| Description | UK Health Data Analytics Network (UK-HDAN) |
| Organisation | Alan Turing Institute |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Partnership to create a network of collaborators in Health data analytics. 3 members of HeRC team sit on the UK-HDAN Steering Group to drive this collaboration forward. |
| Collaborator Contribution | The Alan Turing Institute have provided direction; strategy; scientific and organisational leadership |
| Impact | Series of national and regional workshops for academic and industry audiences; an established network for collaborations; network developed a detailed diagram of health data anlaytics research opportunities and challenges; now developing a research roadmap |
| Start Year | 2015 |
| Description | UK Veterinary and Medical Health Informatics researchers meet in Manchester to launch Farr@Vet |
| Organisation | Animal Health Trust |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | We instigated this network |
| Collaborator Contribution | Recognising both this growing veterinary health informatics research base in the UK, as well as the potential rewards of linking human and animal data together to help achieve 'One Health' outcomes, a group of UK Veterinary and Medical Health Informatics researchers met on the 9th and 10th of March in Manchester to discuss Farr@Vet, a new initiative to harness veterinary electronic health data and build capacity in veterinary health informatics. The meeting included veterinary researchers from the Animal Health Trust, the Animal and Plant Health Agency, Universities of Bristol (Bristol Cat and Generation Pup cohort studies), Edinburgh (Dogslife), Glasgow (equine clinical data), Liverpool (SAVSNET; Small Animal Veterinary Surveillance Network), and Nottingham (CEVM; Centre for Evidence-based Veterinary Medicine), and the Royal Veterinary College (VetCompass), together with colleagues from the Farr Institute (University of Manchester - Farr@HeRC). Farr@Vet recognises the huge opportunities for veterinary health informatics in the UK going forward, particularly if there is collaboration with the Farr Institute. Key areas discussed included the lack of denominator (population size) data for companion animals, the role of coding in data generated by practitioners and other veterinary surgeons, the value of "text mining" to extract meaning from free-text clinical data, and of course sustainability. |
| Impact | Two text mining workshops |
| Start Year | 2016 |
| Description | UK Veterinary and Medical Health Informatics researchers meet in Manchester to launch Farr@Vet |
| Organisation | Animal and Plant Health Agency |
| Country | United Kingdom |
| Sector | Public |
| PI Contribution | We instigated this network |
| Collaborator Contribution | Recognising both this growing veterinary health informatics research base in the UK, as well as the potential rewards of linking human and animal data together to help achieve 'One Health' outcomes, a group of UK Veterinary and Medical Health Informatics researchers met on the 9th and 10th of March in Manchester to discuss Farr@Vet, a new initiative to harness veterinary electronic health data and build capacity in veterinary health informatics. The meeting included veterinary researchers from the Animal Health Trust, the Animal and Plant Health Agency, Universities of Bristol (Bristol Cat and Generation Pup cohort studies), Edinburgh (Dogslife), Glasgow (equine clinical data), Liverpool (SAVSNET; Small Animal Veterinary Surveillance Network), and Nottingham (CEVM; Centre for Evidence-based Veterinary Medicine), and the Royal Veterinary College (VetCompass), together with colleagues from the Farr Institute (University of Manchester - Farr@HeRC). Farr@Vet recognises the huge opportunities for veterinary health informatics in the UK going forward, particularly if there is collaboration with the Farr Institute. Key areas discussed included the lack of denominator (population size) data for companion animals, the role of coding in data generated by practitioners and other veterinary surgeons, the value of "text mining" to extract meaning from free-text clinical data, and of course sustainability. |
| Impact | Two text mining workshops |
| Start Year | 2016 |
| Description | UK Veterinary and Medical Health Informatics researchers meet in Manchester to launch Farr@Vet |
| Organisation | Royal Veterinary College (RVC) |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We instigated this network |
| Collaborator Contribution | Recognising both this growing veterinary health informatics research base in the UK, as well as the potential rewards of linking human and animal data together to help achieve 'One Health' outcomes, a group of UK Veterinary and Medical Health Informatics researchers met on the 9th and 10th of March in Manchester to discuss Farr@Vet, a new initiative to harness veterinary electronic health data and build capacity in veterinary health informatics. The meeting included veterinary researchers from the Animal Health Trust, the Animal and Plant Health Agency, Universities of Bristol (Bristol Cat and Generation Pup cohort studies), Edinburgh (Dogslife), Glasgow (equine clinical data), Liverpool (SAVSNET; Small Animal Veterinary Surveillance Network), and Nottingham (CEVM; Centre for Evidence-based Veterinary Medicine), and the Royal Veterinary College (VetCompass), together with colleagues from the Farr Institute (University of Manchester - Farr@HeRC). Farr@Vet recognises the huge opportunities for veterinary health informatics in the UK going forward, particularly if there is collaboration with the Farr Institute. Key areas discussed included the lack of denominator (population size) data for companion animals, the role of coding in data generated by practitioners and other veterinary surgeons, the value of "text mining" to extract meaning from free-text clinical data, and of course sustainability. |
| Impact | Two text mining workshops |
| Start Year | 2016 |
| Description | UK Veterinary and Medical Health Informatics researchers meet in Manchester to launch Farr@Vet |
| Organisation | University of Bristol |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We instigated this network |
| Collaborator Contribution | Recognising both this growing veterinary health informatics research base in the UK, as well as the potential rewards of linking human and animal data together to help achieve 'One Health' outcomes, a group of UK Veterinary and Medical Health Informatics researchers met on the 9th and 10th of March in Manchester to discuss Farr@Vet, a new initiative to harness veterinary electronic health data and build capacity in veterinary health informatics. The meeting included veterinary researchers from the Animal Health Trust, the Animal and Plant Health Agency, Universities of Bristol (Bristol Cat and Generation Pup cohort studies), Edinburgh (Dogslife), Glasgow (equine clinical data), Liverpool (SAVSNET; Small Animal Veterinary Surveillance Network), and Nottingham (CEVM; Centre for Evidence-based Veterinary Medicine), and the Royal Veterinary College (VetCompass), together with colleagues from the Farr Institute (University of Manchester - Farr@HeRC). Farr@Vet recognises the huge opportunities for veterinary health informatics in the UK going forward, particularly if there is collaboration with the Farr Institute. Key areas discussed included the lack of denominator (population size) data for companion animals, the role of coding in data generated by practitioners and other veterinary surgeons, the value of "text mining" to extract meaning from free-text clinical data, and of course sustainability. |
| Impact | Two text mining workshops |
| Start Year | 2016 |
| Description | UK Veterinary and Medical Health Informatics researchers meet in Manchester to launch Farr@Vet |
| Organisation | University of Manchester |
| Department | The Kellgren Centre of Rheumatology |
| Country | United Kingdom |
| Sector | Hospitals |
| PI Contribution | We instigated this network |
| Collaborator Contribution | Recognising both this growing veterinary health informatics research base in the UK, as well as the potential rewards of linking human and animal data together to help achieve 'One Health' outcomes, a group of UK Veterinary and Medical Health Informatics researchers met on the 9th and 10th of March in Manchester to discuss Farr@Vet, a new initiative to harness veterinary electronic health data and build capacity in veterinary health informatics. The meeting included veterinary researchers from the Animal Health Trust, the Animal and Plant Health Agency, Universities of Bristol (Bristol Cat and Generation Pup cohort studies), Edinburgh (Dogslife), Glasgow (equine clinical data), Liverpool (SAVSNET; Small Animal Veterinary Surveillance Network), and Nottingham (CEVM; Centre for Evidence-based Veterinary Medicine), and the Royal Veterinary College (VetCompass), together with colleagues from the Farr Institute (University of Manchester - Farr@HeRC). Farr@Vet recognises the huge opportunities for veterinary health informatics in the UK going forward, particularly if there is collaboration with the Farr Institute. Key areas discussed included the lack of denominator (population size) data for companion animals, the role of coding in data generated by practitioners and other veterinary surgeons, the value of "text mining" to extract meaning from free-text clinical data, and of course sustainability. |
| Impact | Two text mining workshops |
| Start Year | 2016 |
| Description | UK Veterinary and Medical Health Informatics researchers meet in Manchester to launch Farr@Vet |
| Organisation | University of Nottingham |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | We instigated this network |
| Collaborator Contribution | Recognising both this growing veterinary health informatics research base in the UK, as well as the potential rewards of linking human and animal data together to help achieve 'One Health' outcomes, a group of UK Veterinary and Medical Health Informatics researchers met on the 9th and 10th of March in Manchester to discuss Farr@Vet, a new initiative to harness veterinary electronic health data and build capacity in veterinary health informatics. The meeting included veterinary researchers from the Animal Health Trust, the Animal and Plant Health Agency, Universities of Bristol (Bristol Cat and Generation Pup cohort studies), Edinburgh (Dogslife), Glasgow (equine clinical data), Liverpool (SAVSNET; Small Animal Veterinary Surveillance Network), and Nottingham (CEVM; Centre for Evidence-based Veterinary Medicine), and the Royal Veterinary College (VetCompass), together with colleagues from the Farr Institute (University of Manchester - Farr@HeRC). Farr@Vet recognises the huge opportunities for veterinary health informatics in the UK going forward, particularly if there is collaboration with the Farr Institute. Key areas discussed included the lack of denominator (population size) data for companion animals, the role of coding in data generated by practitioners and other veterinary surgeons, the value of "text mining" to extract meaning from free-text clinical data, and of course sustainability. |
| Impact | Two text mining workshops |
| Start Year | 2016 |
| Description | Withings connected health |
| Organisation | Nokia |
| Department | Withings |
| Country | France |
| Sector | Private |
| PI Contribution | Analysis of data, preparation of manuscript for publication |
| Collaborator Contribution | Provision of data, critical revision of manuscripts. |
| Impact | Paper: Sperrin, M., Rushton, H., Dixon, W., Normand, A., Villard, J., Chieh, A. & Buchan, I (2016). Who Self-Weighs and What Do They Gain From It? A Retrospective Comparison Between Smart Scale Users and the General Population in England. J Med Internet Res, 18(1), e17. eScholarID:296222 | PMID:26794900 | DOI:10.2196/jmir.4767 |
| Start Year | 2014 |
| Description | uMotif |
| Organisation | uMotif |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Research study design for data collection tools (digital pain manikin) and prospective research studies (eg Cloudy with a Chance of Pain) |
| Collaborator Contribution | Design and implementation of the data collection platform. Data management services. |
| Impact | Publications from Cloudy with a Chance of Pain and Digital Pain Manikin. Major international media interest in Cloudy results |
| Start Year | 2015 |
| Description | uMotif |
| Organisation | uMotif |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Co-design of smartphone application to collect data on musculoskeletal disease, including use of accelerometer and GPS data |
| Collaborator Contribution | Use of their configurable smartphone application and supporting systems |
| Impact | MRC Confidence in Concept award Funding for Cloudy with a Chance of Pain, extending work to linkage to wearable devices |
| Start Year | 2013 |
| Title | Data Selection |
| Description | A method of selecting data, the method comprising, receiving data indicating a first requirement and identifying first records stored in a first database. The first records relate to first data subjects and the identification is based upon the first requirement. The first data subjects cannot be identified from the records of the first database. Second records are identified, the second records being stored in a second database and relating to the first data subjects. The first data subjects can be identified from the identified records of the second database. Each of the second records corresponds to a respective one of the first records, and the identification of the second records is based upon the first requirement. |
| IP Reference | US2017032145 |
| Protection | Patent granted |
| Year Protection Granted | 2017 |
| Licensed | Yes |
| Impact | Spun out www.nweh.co.uk and ran GSK Salford Lung Study and other clinical trials on this basis |
| Title | STELAR Asthma eLab |
| Description | We created a secure web-based research environment (Asthma e-Lab; www.asthmaelab.org) to support consistent recording, description and sharing of data, computational statistical methods and emerging findings across the cohorts. The Asthma e-Lab serves as a data repository populated with a unified dataset from our well-defined birth cohorts; in addition, it provides the computational resources and a scientific social network to support timely, collaborative research across the consortium. The activities of data managers and investigators from the five STELAR sites are visible to one another, supporting team coordination and peer support, whilst creating a record of activity to ensure transparency. Researchers inputting the data can see how the data are being used in the analyses, and receive on-line training via the e-Lab, thereby harmonising the relevant knowledge, skills and practices needed to create a consistent STELAR dataset. Emerging findings are shared with all sites via the e-Lab, linked to explanations of analytical methods that might not be familiar to all participants, thereby creating a scientific social network enriching the on-going modelling and interpretation. |
| IP Reference | |
| Protection | Protection not required |
| Year Protection Granted | 2016 |
| Licensed | Yes |
| Impact | We have created conditions that will facilitate data sharing with the consortium of 12 US-based birth cohorts (CREW). NIH has just announced that CREW were awarded funding through the Environmental influences on Child Health Outcomes (ECHO) programme, and CREW will utilise our UK STELAR knowledge management platform (eLab). This will provide a worldwide platform to help solve the global problem of asthma. Our flexible platform will be able to accommodate other cohorts and disease outcomes in future. |
| Title | FARSITE |
| Description | FARSITE is a rapid 'search and find' tool designed to preserve patient confidentiality. The FARSITE software provides a safe, convenient and effective way for the GP to control the recruitment of their patients into clinical research, whilst allowing NHS-based researchers to run complex and powerful searches over anonymised population level health record data. Since November 2013 FARSITE has been utilised for a number of research projects covering new disease areas such as vasculitis, and supporting recruitment to a range of clinical projects. The Farr funded rollout of FARSITE has continued at pace throughout 2014/15. This partnership with stakeholders across the North's Academic Health Science Networks (AHSN) is a direct result of investment from the Farr Institute Capital award enabling clinical research networks and AHSN teams to utilise the FARSITE platform for service improvement and efficient trial recruitment. |
| Type | Therapeutic Intervention - Medical Devices |
| Current Stage Of Development | Small-scale adoption |
| Year Development Stage Completed | 2014 |
| Development Status | Under active development/distribution |
| Impact | The FARSITE platform for rapid feasibility analysis and recruitment in clinical trials was extended by adding new functionality from research in HeRC on care pathway analysis, which was presented and won a distinguished paper prize at Medinfo 2013 (world's top Health Informatics conference). The prototype software, COCPIT, is being incorporated into FARSITE in consultation with NHS users by North West eHealth. Ongoing research in HeRC will add new stratification models to this tool to help both commissioners and clinical audit teams. |
| URL | http://www.nweh.org.uk/content/farsite |
| Title | GSK Relvair Salford Lung Study successfully reported and comparative observational study for Hawthorne effect "CHESS" about to be reported |
| Description | CHESS: CPRD_COPD Hawthorne Effect Study in Salford: A UK cohort study to characterise patients enrolled in the Salford Lung Study and to evaluate a potential Hawthorne effect. The Salford Lung Study is a pragmatic randomised controlled trial (pRCT) to test the effectiveness of a novel medicine compared with standard of care among patients with Chronic Obstructive Pulmonary Disease (COPD). A pragmatic trial tests the effectiveness of the drugs in everyday clinical practice, as opposed to under strict clinical trial conditions. It is the first ever pre authorisation pragmatic randomised controlled trial. However, people often act differently when they are aware of being under surveillance (this applies to both patients and clinicians) - known as the Hawthorne Effect. The aim of this study is to compare the patients in the standard of care arm of the Salford Lung Study with other COPD patients in primary care. We can then advise as to whether the results from the trial are indeed applicable to everyday clinical practice. We are using a combination of an observational cohort of COPD patients from the Clinical Practice Research Datalink (CPRD) linked with Hospital Episode Statistics (HES) and Office for National Statistics (ONS) data, and trial data from the control arm of the Salford Lung Study (SLS). We are comparing baseline characteristics (age, social economic status, co-morbidities, etc) of the SLS control arm with the CPRD cohort to place the members of the SLS in a wider context. We are then creating models that compare the rate of COPD exacerbations in the two groups to see if the rates of COPD exacerbation in the SLS are unusual. We will be considering the natural variation in the CPRD cohort which includes patients from all over the UK and assessing whether the SLS patients fit within this. The study is registered as an EU-PAS study and holds the ENCePP study seal. This represents external recognition of high standards throughout the research process - see www.encepp.eu. |
| Type | Preventative Intervention - Behavioural risk modification |
| Current Stage Of Development | Initial development |
| Year Development Stage Completed | 2017 |
| Development Status | Under active development/distribution |
| Impact | It is rare for the effectiveness of drugs in routine clinical practice to be known pre (or even post) authorisation. The SLS aims to uncover exactly this. It is therefore important to assess this key aspect of the design to provide more evidence to clinicians who will potentially be prescribing the drugs, ultimately leading to better care for COPD patients. The outcome will be to assess whether there is a presence of the Hawthorne effect. Our findings will be presented alongside the trial results to aid their interpretation. If the results from the SLS are positive, it is important for doctors and clinicians to know to what extent these results are generalizable to routine practice, i.e. the conditions in which they will be prescribing the drug. |
| URL | http://www.herc.ac.uk/research_project/hawthorne-effect-study-salford/ |
| Title | WHEAT trial |
| Description | This pilot trial which will enrol 500 premature babies at 20 sites in order to evaluate different feeding times around blood transfusion, testing the effects on necrotising enterocolitis. The neonatal disease registry (with routinely collected data) will be used to measure the outcomes. |
| Type | Preventative Intervention - Nutrition and Chemoprevention |
| Current Stage Of Development | Late clinical evaluation |
| Year Development Stage Completed | 2016 |
| Development Status | Under active development/distribution |
| Impact | This overall aim of this pilot trial (PI C Gale Imperial) is to develop a system that will embed randomised point-of-care trials (PoCT) within routine care in a manner akin to the Medical Research Council funded "mega-trials" that were considered an integral component of paediatric cancer care and revolutionised the treatment of childhood leukaemia from the 1970's |
| URL | http://www.hra.nhs.uk/news/research-summaries/wheat-withholding-enteral-feeds-around-packed-red-cell... |
| Title | Deidentification of veterinary clinical narratives |
| Description | The clinical narratives contained within veterinary electronic health records often contain unintentional personal details such as the name of the attending veterinary surgeon and the name and contact details of owners and their relatives. A tool was developed by a HeRC-funded PGR at University of Liverpool to automatically recognise such details and replace the text with context-specific placeholders that enable the clinical narrative to be read without loss of meaning. |
| Type Of Technology | Software |
| Year Produced | 2016 |
| Impact | The inclusion of personal data in veterinary clinical narratives is commonly encountered by many groups working to develop veterinary health informatics. The tool described is currently being used by several collaborator groups in the UK. |
| Title | HErCoOl |
| Description | Error correction software for next-generation sequencing data based on k-mer spectrum. |
| Type Of Technology | Software |
| Year Produced | 2014 |
| Open Source License? | Yes |
| Impact | publications and usage in the research field |
| URL | http://sourceforge.net/projects/hercool/ |
| Title | MethodBox |
| Description | A gateway to social science survey variable and scripts, and a social sharing platform for sharing scripts and variable sets. Finding the variables you need to support a particular research question can be time consuming. Wading through hundreds of pages of PDF documents, codebooks and metadata and then trying to find the exact column in a huge spreadsheet can be very frustrating. MethodBox gets you to the variables faster and lets you download only the data you need. You can also share your methods with others to allow them to adopt best practice quicker than before. MethodBox enables you to browse and download data files, share your resources, find fellow researchers with similar interests and share your knowledge. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2011 |
| Open Source License? | Yes |
| Impact | Influenced the redevelopment of the ESRC UKDS. Decommissioned in 2017 |
| URL | https://methodbox.cs.man.ac.uk/ |
| Title | The use of text-mining methods to automatically extract clinically-relevant information from veterinary clinical narratives and to classify veterinary consultations based on presenting signs |
| Description | Veterinary clinical narratives are often unstructured, unpunctuated and contain many abbreviations and colloquialisms. A software tool was developed by a HeRC-funded PGR at the University of Liverpool that used a series of nested regular expressions to automatically extract clinically-relevant information from the clinical narratives, including temperature, pulse and respiration rates, presenting signs (taking account of negation) and prescribed treatments. |
| Type Of Technology | Software |
| Year Produced | 2016 |
| Impact | This tool is starting to be used within the SAVSNET team to rapidly extract valuable clinical information and to classify individual consultations based on presenting signs without the need for the attending veterinary surgeon to enter clinical codes. Clinical coding systems are available in the veterinary field but they are utilised in irregular and unpredictable ways. The use of the described tool enables the large number of consultations in a database to be rapidly and consistently classified. |
| Title | US Patent 9,471,637 awarded for work on clinical trials software |
| Description | A method of selecting data, the method comprising, receiving data indicating a first requirement and identifying first records stored in a first database. The first records relate to first data subjects and the identification is based upon the first requirement. The first data subjects cannot be identified from the records of the first database. Second records are identified, the second records being stored in a second database and relating to the first data subjects. The first data subjects can be identified from the identified records of the second database. Each of the second records corresponds to a respective one of the first records, and the identification of the second records is based upon the first requirement. |
| Type Of Technology | Software |
| Year Produced | 2016 |
| Open Source License? | Yes |
| Impact | Embodiments of the software can be used to perform feasibility analysis for use in the design of clinical trials, and for recruitment of patients into the clinical trial while maintaining the requirements of privacy. The software has applications extending beyond the use in the design of and recruitment for clinical trials as described above. The software has application in any area where it is required to maintain privacy of data across a notional boundary. The application may be used in banking applications where it is it is desirable to provide one set of users, possibly external to the bank, with limited access to customers' financial data. |
| URL | http://google.com/patents/US9471637?cl=en#backward-citations |
| Title | eLab |
| Description | The eLab is a multi-purpose platform which provides a secure way for researchers to collaborate in the analysis of confidential healthcare data, allowing end-users to share and discuss their analysis methods and findings. The eLab platform is currently being used to develop many of our projects including the MRC-funded STELAR project and international collaborations such as iFAAM (EC funded), enabling medical researchers to work together on shared datasets. It will also be deployed for two of the recently-awarded MRC strategic infrastructure funded projects (see Further Funding), as well as the CHIP-SET project being led by John Ainsworth, Carole Goble and Goran Nenadic. |
| Type Of Technology | Webtool/Application |
| Year Produced | 2014 |
| Impact | In late 2014 the STELAR eLab started to be used to store and harmonise datasets provided by a number of collaborators. |
| URL | https://www.asthmaelab.org/share/page |
| Company Name | CareLoop Health |
| Description | CareLoop Health develops an app and text-based system for self-reporting of symptoms by people with serious mental illness (SMI), aiming to improve community-based care and early clinical intervention. |
| Year Established | 2021 |
| Impact | Early stage - no impact yet. |
| Website | https://www.careloop.health/ |
| Company Name | Affigo C.I.C. |
| Description | |
| Year Established | 2015 |
| Impact | Not yet. |
| Description | "Pragmatic" or "Point of Care" trials: their importance for public and patients and helping RECs review them fairly. |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | The Health Research Authority (HRA) recognizes the increasing interest in and importance of pragmatic and point of care trials comparing treatment options already in use in routine clinical care *. Much clinical practice has little basis in evidence and these trials are seen as a way of addressing uncertainties about the relative merits of different (alternative) treatment options. Given, in addition, the public support for such research, the HRA is funding this workshop to help Research Ethics Committees (RECs) review these trials proportionately. It will look specifically at defining such trials in the broad context of current research and the way in which consent should be sought. The workshop is aimed at REC officers and members but will also be of interest to researchers in this field who submit to RECs. As an outcome we will provide training material for RECs as "Questions and Considerations" and a meeting report. *Pragmatic or point of care trials compare the effects of different decisions in usual clinical practice. They don't deny effective treatment, rather they compare accepted or licensed interventions / therapies with no extra interventions beyond routine care. Similar trials are sometimes referred to as "Low-intervention Clinical Trials of Investigational Medicinal Products" under the new European Union Clinical Trial Regulations or "Comparative effectiveness trials" in North America and elsewhere Objectives i. To describe and define Pragmatic and Point of Care Trials and their place in clinical care ii. To describe barriers to their conduct iii. To outline the importance of public and patient involvement in their design and conduct iv. To help RECs consider how they should identify and review these trials v. To consider and define appropriate consent vi. To contribute to the development of guidance |
| Year(s) Of Engagement Activity | 2015 |
| URL | http://www.hra.nhs.uk/wp-content/uploads/2016/01/01-16-12Jii.-Point-of-Care-trials-Draft-Meeting-Not... |
| Description | #BritainBreathing co-design workshops |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Delivered #BritainBreathing co-design workshops at Manchester Musuem. The workshops involvined 35 members of the public co-designing an app, using paper prototyping activities, to improve self-management and generate data on the frequency and location of allergy symptoms. |
| Year(s) Of Engagement Activity | 2015 |
| URL | http://britainbreathing.org/ |
| Description | #Datasaveslives |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | #datasaveslives is designed to create a public face for the array of research projects that are taking place in the multidisciplinary world of eHealth, mHealth and eResearch. Through the use of case studies, good new stories, open and transparent explanations of research and a multi-platform approach to engaging with the public, #datasaveslives is seeking to overturn the negative perceptions that some members of the public have about the use of patient data in research. Having been building momentum over the last twelve months on social media platform Twitter the campaign was enthusiastically supported by speakers and delegates at the international Digital Health Assembly held recently in Cardiff. Over 20 senior representatives from The Farr Institute, the World Health Organisation (WHO), Siemens, The universities of Liverpool, Cardiff and Manchester alongside patient representatives and HeRC's leadership team lent their support to the campaign by having their photo taken whilst holding a #datasaveslives placard. The aim of #datasaveslives is to provide a vehicle for academics, researchers and developers to highlight their work, its impact and the UK's rigorous data-protection processes to a wider and more mainstream public audience. |
| Year(s) Of Engagement Activity | 2014,2015 |
| URL | http://www.herc.ac.uk/2015/02/27/datasaveslives_public_campaign/ |
| Description | #datasaveslives animation |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | In 2018, representatives from the Health eResearch Centre, in partnership with colleagues at The Farr Institute and Connected Health Cities, developed a short 3 minute animation. The aim of the animation was to communicate to a broad public audience how health data is used by universities to conduct research. The animation will be complete on the week commencing 19th March 2018 and will be shared widely across the partners networks and through a digital marketing campaign. The animation will also be used by HeRC, The Farr Institute and Connected Health Cities at public engagement events and activities to help quickly explain the role universities play in improving health and care services for patients. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://www.datasaveslives.info |
| Description | #datasaveslives animation videos |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | A new animation has been created to answer questions about the use of patient data by UK universities, researchers and scientists. |
| Year(s) Of Engagement Activity | 2018,2019 |
| URL | https://www.connectedhealthcities.org/2018/04/new-datasaveslives-animation-launched/ |
| Description | 2nd International Summit on Trustworthy Reuse of Health Data |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Type Of Presentation | Workshop Facilitator |
| Geographic Reach | International |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | The HeRC Director was invited to run 3 workshops as part of a policy-informing exercise at the 2nd International Summit on Trustworthy Reuse of Health Data. The workshops engaged with Industry partners (Bio-pharmaceutical, ICT, Management consultancy) and EU data privacy policy makers. Results of the summit published by the International Medical Association. |
| Year(s) Of Engagement Activity | 2013 |
| Description | A Framework for Large-scale Modelling of Population Health |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | A Framework for Large-scale Modelling of Population Health at Berkley, California's Microsoft e-Science 2010. |
| Year(s) Of Engagement Activity | 2010 |
| Description | A workshop to discuss a University Institute of Health Services Research |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | A workshop to discuss a University Institute of Health Services Research held by Martin Tickle, Manchester, June 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | Adventures in Connected Health |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other audiences |
| Results and Impact | Adventures in Connected Health at University of Manchester, Manchester's Connected Health Innovation Centre. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Article in online patient-facing magazine |
| Form Of Engagement Activity | A magazine, newsletter or online publication |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Announcement of the study in 2016 Autumn edition of the e-magazine of Kidney Research UK (aimed at patients, donors, clinicians). |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://issuu.com/kidney_research_uk/docs/kr10019_-_update_autumn_2016_-_issu |
| Description | BBC Breakfast |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Video feature and then interview on the 'BBC Breakfast couch'. Viewing figures of 7M. Significant public response following broadcast with recruitment spike of around 4000 new registrants that day. Recruiting one new user per second following the show |
| Year(s) Of Engagement Activity | 2016 |
| Description | BBC Breakfast; Cloudy with a chance of Pain Interview |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor Will Dixon and his team's 'Cloudy with a Chance of Pain study' which has found a link between chronic pain conditions and the weather has been widely covered in today's regional, national and international media. Professor Dixon himself was live on the BBC Breakfast sofa. 24/10/2019 |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.bbc.co.uk/programmes/m0009n6x |
| Description | BBC News Online: People 'more likely to feel pain on humid days': |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | People with long-term health problems such as arthritis are more likely to feel pain on humid days, a study has suggested. Folklore suggests the cold makes pain worse - but there is actually little research into the weather's effects. And this University of Manchester study of 2,500 people, which collected data via smartphones, found symptoms were actually worse on warmer, damper days. 24/10/2019 |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.bbc.co.uk/news/health-50151723 |
| Description | BBC World Service Broadcast - Health Check (How the weather influences pain ) |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | BBC World service programme produced by Claudia Hammond Professor Will Dixon How the weather influences pain 31/10/19 https://www.bbc.co.uk/sounds/play/w3csy9kn |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.bbc.co.uk/sounds/play/w3csy9kn |
| Description | BBC2's Trust Me I'm a Doctor |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Broadcast planned for January 2016. Should drive recruitment Due to broadcast Jan 2016 |
| Year(s) Of Engagement Activity | 2015 |
| Description | Blackpool and Fylde College 'Introduction to Big Data in Health' |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Undergraduate students |
| Results and Impact | Outreach activity led by the HeRC Education and Training Team Excellent engagement from students, who asked lots of questions and showed genuine interest in the work of HeRC. The team have since been invited to present further lectures in the future. |
| Year(s) Of Engagement Activity | 2014 |
| Description | BlueDot Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | HeRC + CHC staff hosted a number of data-themed engagement activities at BlueDot Festival, including voting booths designed to stimulate a conversation surrounding sharing health data and interactive games |
| Year(s) Of Engagement Activity | 2018 |
| Description | Bluedot Science festival at Jodrell Bank |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Taking questions about health data to the people, volunteers from the HeRC/CHC co-ordinating Hub spent three days talking all things health-tech related in a family-friendly exhibition and public-survey. Delivered over three days of sunshine in the shadows of the iconic Lovell Telescope, Bluedot fuses science, music and art for over 15,000 curious festivalgoers. Alongside over 20 other science exhibitors, the HeRC/CHC reps engaged in conversations about the value of patient data in research with visitors of all ages. Situated in the Jodrell Bank's Star Field, attendees at the #datasaveslives stand were able to take-part in a trio of data-inspired activities ranging from data friendship bracelet making (each thread represented a different data set), to a data-jigsaw and finally an ever-increasing data-chain highlighting the number of pro-data sharing supporters visiting the stand. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.connectedhealthcities.org/2017/07/datasaveslives-goes-intergalactic-jodrell-banks-bluedo... |
| Description | British Science Festival talk |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Talk on Cloudy with a Chance of Pain, including engagement rates and the role of citizen science in research. Press conference to coincide with release of early findings from the Alan Turing Institute summer school. |
| Year(s) Of Engagement Activity | 2016 |
| Description | British Science Week |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | HeRC hosts a stall for British Science Week discussing projects and careers in health research with local pupils |
| Year(s) Of Engagement Activity | 2018 |
| Description | Building research capacity in public health- dragons den event with Public Health England |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Other audiences |
| Results and Impact | Public Health England and The University of Manchester held a one day event for academic and service professionals across Public Health in Greater Manchester to build capacity and encourage joint working across the academic and service sectors. The event consisted of a series of lightening presentations followed by a Dragon's Den where potential research projects on that theme were pitched to the Den. Winning pitches will proceed to further joint work up of proposals and submission for research funds. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://events.manchester.ac.uk/event/event:np7-ii7gxhw7-34cfap/building-research-capacity-in-public-... |
| Description | CHESS Steering Committee Meeting, Salford |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | CHESS Steering Committee Meeting, Salford, June 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | CNN Website Piece: Humid, windy days worse for pain, says new study: |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Report on CNN website by Professor Will Dixon on the Cloudy with a Chance of pain project. Humid, windy days with low pressure make pain worse in those with long-term health conditions, according to new research. People with conditions like arthritis, fibromyalgia, migraine and neuropathic pain are 20% more likely to suffer pain in such weather, reveals a study carried out by scientists from the University of Manchester, UK. 24/10/2019 |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://us.cnn.com/2019/10/24/health/pain-humidity-study-scli-intl-scn/index.html |
| Description | Chair of session at European Renal Association congress 2016 |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Organised and chaired a scientific session at the European Renal Association conference (Vienna, 2016). The session was called 'Including the patient perspective in renal care'. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Cheltenham Science Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Stall at Cheltenham Science Festival to raise awareness of Cloudy with a Chance of Pain and the role of citizen science in research studies. No stats on impact. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Citizens Jury |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | A cross-section of 18 adults from Greater Manchester were selected to form a Citizens Jury to consider a number of questions relating to health records. The Jury met on three consecutive days in January 2016 to hear from and ask questions of experts, and to deliberate. To validate the outcomes of the process, a second citizens' jury with 18 different jurors was also run in January. The two juries tackled the same "jury mission", specific questions that the jury must answer as a group. Each individual also completed a start-of-jury questionnaire, and an end-of-jury questionnaire on their views about these questions. The three-day process was facilitated by Kyle Bozentko, a director of the Jefferson Center in the USA, and Amanda Hunn from the Health Research Authority. Jurors heard presentations from, and were able to ask questions of, five expert witnesses. To protect against bias, the jury design and other materials were reviewed by an independent oversight panel. More information, including the jury findings, will be published in March 2016. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.herc.ac.uk/get-involved/citizens-jury/ |
| Description | Clinical Advisory Council for Computer Science Corporation (CSC) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | Yes |
| Geographic Reach | International |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | The HeRC Director sat on the Clinical Advisory Council for Computer Science Corporation (CSC). At this one day workshop the HeRC Director helped envision the future landscape of healthcare computing and how the ICT industry-academia-healthcare interface may evolve. Follow up meetings on innovations in clinician driven statistical analysis have been taking place as a result of parallel meetings with CSC theme leads at the workshop. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Cloudy with a Chance of Pain Patient and Public Involvement Workshops |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Held a workshop for patients with rheumatoid arthritis to inform the design of the cloudy with a chance of pain app in collaboration with uMotif. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Community Health e-Lab: Mobilising an Ethical Framework for Community-serving Uses of Individual Health Records |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Community Health e-Lab: Mobilising an Ethical Framework for Community-serving Uses of Individual Health Records at St Andrew's University's Scottish Health Informatics Programme Meeting 2013 |
| Year(s) Of Engagement Activity | 2013 |
| Description | Community Reporter project on use of health data by senior citizens |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | We undertook a citizen engagement project that aimed to capture older people's view on health data through community reports. We trained a total of eighteen older people (aged =55 years) in two Greater-Manchester areas to become Community Reporters. Community reporting is a citizen engagement method that enables people to share personal stories -either their own or by interviewing others- on a topic by creating and sharing video recordings. We designed a community reporter training around the topic of 'Health Data' in collaboration with community workers and older citizens. Over a 6-week period, participants learned how to create, edit and upload their community reports. The community services we collaborated with are planning to continue making community reports and/or introducing health technology training as part of their portfolio. We will present the results at a seminar + at a scientific conference. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://www.herc.ac.uk/research_project/community-reporters/ |
| Description | Computer Science & Big Data |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | Computer Science & Big Data at Surgeon's Hall, Edinburgh's Farr Institute Inaugural Scientific Meeting |
| Year(s) Of Engagement Activity | 2014 |
| Description | Connected Health Cities Advisory Board Meeting, Manchester |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Connected Health Cities Advisory Board Meeting, Manchester, November 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | Connected Health Innovation Centre: Wearable Devices Seminar |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | This event provide an opportunity for discussion of a current 'hot topic' in information technology, and networking with colleagues across disciplines in an informal setting. |
| Year(s) Of Engagement Activity | 2014 |
| URL | https://www.informatics.manchester.ac.uk/news/Pages/ConnectedHealthInnovationCentreMaySeminar.aspx |
| Description | Connected Healthcare: Leveraging data and technology to improve health and social care panel, Pharma Integrates 2016, London |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Connected Healthcare: Leveraging data and technology to improve health and social care panel, Pharma Integrates 2016, London, November 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | Creative Digital Sector Engagement |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | The HeRC Director was invited by Creative England to plan stimuli for the creative digital sector to develop health businesses. An incubator fund is now being planned. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Dementia Patient and Public Involvement Workshops |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Patients, carers and/or patient groups |
| Results and Impact | Delivered a series of workshops and meetings focusing on acceptability of dementia research using wearables. Involved over 30 patients, carers and members of the public. Produced recommendations which informed purchasing decisions of wearable devices to be linked with the Dementia's Platform UK project. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Developing the UK infrastructure for e-health research |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Developing the UK infrastructure for e-health research at Royal Society of Medicine, London's Royal Society of Medicine - Electronic health data for population health benefit. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Digital Academy Steering Group, London |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Digital Academy Steering Group, London, December 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | Electronic Health Data for Population Health Benefit (at The Royal Society of Medicine) |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Health professionals |
| Results and Impact | Organised by the Royal Society of Medicine in association with The Farr Institute, this one-off meeting was designed to discuss the argument that electronic health data has the potential to change the way we think and act about every aspect of healthcare - from risk and prevention to diagnosis and treatment. HeRC represented by talks by Tjeerd Van Staa and John Ainsworth. Kate McAllister Chaired a session in her capacity as President of the Epidemiology and Public Health Section of the RSM. Kieran O'Malley also attended and co-ordinated. This meeting was an opportunity to meet with experts, learn of governmental developments and enhance attendees' knowledge of the most up-to-date innovations in the use of digital care records. |
| Year(s) Of Engagement Activity | 2014 |
| URL | https://www.rsm.ac.uk/events/epe02 |
| Description | EnTRUSTed is a large scale hospital simulation game-a-thon |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | EnTRUSTed is a large scale hospital simulation game-a-thon developed by the Health eResearch Centre and the Farr Institute in conjunction with Connected Health Cities, where the functions of an NHS Trust and roles within in it are performed by its many participants. Each participant plays a role of a key decision maker within a fictional NHS hospital. To succeed, participants will need to efficiently act according to their roles and responsibilities, perform allocated tasks and negotiate the various challenges that they will face over the day |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://vimeo.com/295407891 |
| Description | Engagement and partnership with Deloitte |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | Deloitte (London) met with the HeRC Director and planned a partnership in developing a new method for healthcare intelligence around the "e-Lab" model from HeRC and a management consultancy model from Deloitte. An initial project in cancer services redesign is planned with potentially important policy and practice impacts. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Engagement meeting with AstraZeneca (Industry Partner) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Type Of Presentation | Keynote/Invited Speaker |
| Geographic Reach | Regional |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | The HeRC Director was invited to consult on 'big data' analytics with coded health record data. Strengthened links between HeRC and its Industry partners. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Engagement with The Association of the British Pharmaceutical Industry (ABPI) |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | ABPI visited HeRC to discuss health informatics for personalised/stratified medicine. The HeRC Director briefed the ABPI's Regional Partnership Manager for the North. The HeRC Director provided ABPI with a document detailing thoughts in this area as a follow up to the meeting. Influencing the pharmaceutical industry thinking and strategy in eHealth Research. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Engagement with the BBC, Peel Holdings and MediaCity UK |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | The HeRC Director was invited by Peel Holdings, BBC and MediaCity UK to discuss e-health innovation and the creative digital sector. The Farr Institute Industry Forum will be held free of charge at a Peel building for digital innovation in Media City UK. In addition, a series of lectures with BBC research is also being planned from HeRC. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Expert witness to the Jury making the case for: To what extent should patients control access to patient records? |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Study participants or study members |
| Results and Impact | Expert witness to the Jury making the case for: To what extent should patients control access to patient records? at Friends House, Manchester for Manchester Citizen's Jury. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Exploring new ways for patients to consent for research & use of health data |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | Reusing anonymised health data from patient records provides opportunities for advancing health research. However, the media and some members of the public have raised concerns. Our current area of research explores patient views on the use of anonymous electronic patient records for research purposes. In particular, we have been exploring a new model known as 'dynamic consent', which would allow individuals to give consent to use their anonymised data for specific purposes (e.g. specific research projects). People could also access feedback about research results, view who had access to their data and change consent preferences over time. To explore the practicalities, we developed a prototype of an electronic 'dynamic consent' system for tablet devices that could be used in clinical settings. We held a workshop at The University of Manchester on 27th November 2014, and 30 members of the public attended. The aim was to explore public views on the electronic dynamic consent system. We explained key concepts and discussed two scenarios where dynamic consent could be used. Attendees also had used and discussed a prototype of the electronic system using a tablet device. |
| Year(s) Of Engagement Activity | 2014 |
| URL | http://www.inflammation-repair.manchester.ac.uk/Musculoskeletal/research/CfE/eHealth/dynamicconsent/... |
| Description | GM CHC Industry Workshop, Manchester |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | Inaugural GM CHC Industry Workshop, Manchester April 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | GM CHC Steering Group, Manchester |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | GM CHC Steering Group meetings, Manchester |
| Year(s) Of Engagement Activity | 2016 |
| Description | GM Connect Executive Steering Board, Manchester |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Policymakers/politicians |
| Results and Impact | GM Connect Executive Steering Board, Manchester, October 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | H@PPI (HeRC @ Patient and Public Involvement) Forum |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Patient and Public Forum established to inform strategic-level decision making and embed public involvement throughout HeRC research themes. July 2015 marked the first birthday of the Forum which has decided a priority plan for action including reviewing HeRC research proposals, influencing research priorities and external policy e.g. evidence at the National Data Review PPI Forum members have provided input in the Hyper Island activity (September 2014), and National Information Board Strategy Meeting (October 2014) |
| Year(s) Of Engagement Activity | 2014,2015,2016 |
| URL | http://www.herc.ac.uk/get-involved/join-our-forum/ |
| Description | HeRC Schools Engagement Workshops |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | HeRC delivered workshops at two high schools in the region as follows: Trinity High School, 21 July, 2015 - 25 Year 10 school pupils learned more about clinical trials and how data gathered in this way can be used to conduct important health research. - Pupils were invited to participate in a mocked-up trial and generate hypothesis based on their findings. - The lesson was designed to encourage more pupils to consider studying statistics post-GCSE. Altrincham Grammar School for Girls, 13th November 2015 - 40 Year 10 and 11 students studying GCSE Computer Science were tasked with linking together data to find a link between sugar consumption and tooth decay. Following this they were challenged to design an app that could be used to gather data that would fuel research into preventing tooth decay in the future. - 53% of the pupils attending said that they would consider a career in health research after participating in the event. - The lesson was designed to encourage students to consider careers in health data science. |
| Year(s) Of Engagement Activity | 2015 |
| URL | http://www.herc.ac.uk/case_studies/datasaveslives-schools-engagement-activity/ |
| Description | HeRC led School Engagement at The Farr Institute International Conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Activity delivered at The University of St Andrews with pupils from Bell Baxter High School and Madras College, 28 August, 2015. 50 pupils studying statistics as part of their Scottish Highers, spent a day learning more about careers in health data science as part of The Farr Institute's International Conference. Students took part in a series of interactive activities including a lesson in unpicking the evidence in data sets and a Q&A session with researchers. The aim of the session was to make pupils aware of how statistics can be applied in health research. |
| Year(s) Of Engagement Activity | 2015 |
| URL | http://www.farrinstitute.org/events/56/2015-08-26/the-farr-institute-international-conference-2015.h... |
| Description | HealTex Launch Event, Manchester |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | HealTex Launch event, MOSI, Manchester November 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | Healthcare Data - simply a matter of engineering? |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Supporters |
| Results and Impact | Healthcare Data - simply a matter of engineering? at The Møller Centre, Cambridge's ICT KTN Event and HealthTech & Medicines KTN, "Big Data in Health" |
| Year(s) Of Engagement Activity | 2014 |
| Description | Healthcare Data Analysis at Scale: Opportunities and Challenges |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Healthcare Data Analysis at Scale: Opportunities and Challenges at University of Exeter, Exeter's Networkshop43, JISC. |
| Year(s) Of Engagement Activity | 2015 |
| Description | Hyper Island Event |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Postgraduate students |
| Results and Impact | TBC |
| Year(s) Of Engagement Activity | 2014 |
| Description | ITV News : Arthritis pain 'worse on humid, windy days' |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | ITV News piece on website - Professor Will Dixon on Cloudy with a Chance of Pain project People with arthritis are more likely to feel pain on humid, windy days - meaning it may be possible for sufferers to plan activities around a pain forecast. Scientists from the University of Manchester found sufferers were 20% more likely to be in pain on days that are humid and windy with low atmospheric pressure than on days with average weather. 24/10/2019 |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.itv.com/news/2019-10-24/arthritis-pain-worse-on-humid-windy-days/ |
| Description | Informatics for Health conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Other audiences |
| Results and Impact | BMC Medical Informatics and Decision Making attended Informatics for Health 2017 in Manchester at the end of April. Combining Medical Informatics Europe 2017 (from the European Federation for Medical Informatics) with the Farr Institute International Conference 2017, the congress provided a platform for talks and sessions covering a wide range of topics in health informatics from the use of linked data in health research to information technology from the patient perspective. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://informaticsforhealth.org/ |
| Description | Interoperability Summit Event, London |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Interoperability Summit Event, London, November 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | Interview for an article in The Telegraph |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | The HeRC Director and Co-Investigator were ask to comment on a story by The Telegraph on their study published in the International Journal of Obesity. The article raised the profile of HeRC related research with the public. Communication of current research findings on obesity to the public was achieved. The HeRC Directors comments highlighted the need for government approach to this issue to be more detailed. |
| Year(s) Of Engagement Activity | 2013 |
| URL | http://www.telegraph.co.uk/health/healthnews/10282592/Britons-have-stopped-getting-fatter.html |
| Description | Interview for article in the Daily Mail |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | The HeRC Director and Co-Investigator were asked to comment on an article by the Daily Mail detailing the results of their study on obesity rates which was published in the International Journal of Obesity. The article raised the profile of HeRC related research with the public. Communication of current research findings on obesity to the public was achieved. The HeRC Directors comments highlighted the need for the government approach to this issue to be more detailed. |
| Year(s) Of Engagement Activity | 2013 |
| URL | http://www.dailymail.co.uk/health/article-2408931/Britains-obese-continue-weight-despite-drop-nation... |
| Description | Interview on BBC Breakfast on the cloudy with a chance of pain project |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | HeRC Investigator Will Dixon was interviewed on BBC Breakfast to describe the release of a new smart phone app called cloudy with a chance of pain. The app allows arthritis or chronic pain suffers to track their symptoms whilst also recording GPS weather data to allow researchers to investigate the hypothesis that certain weather conditions can affect pain symptoms. |
| Year(s) Of Engagement Activity | 2016 |
| URL | https://twitter.com/CloudyPain/status/690462314978480130 |
| Description | Introduction to The Farr Institute |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Introduction to The Farr Institute at Regents University, London's NHS-HE Forum (Janet) |
| Year(s) Of Engagement Activity | 2013 |
| Description | Invited lecture at 9th UK Annual Dialysis conference |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | I was an invited speaker at the 9th UK Annual Dialysis conference (Manchester, Sept 2016) where I talked about the project as part of my presentation on 'Patient participation in their care'. Around 250 people attended, representing a mix of clinicians, allied health professionals and patients. There was a lively discussion afterwards about the potential of the research (mainly sparked by patients) + what would be needed to achieve that potential. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.renal.org/event/2016/09/29/default-calendar/9th-uk-annual-dialysis-conference#sthash.0BCy... |
| Description | Invited lecture at the International Seminar on Renal Epidemiology (Paris, 15-16 September 2016) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Invited lecture for an international group of approx. 50 renal epidemiologists (incl from France, UK, Netherlands, Australia, USA, etc.) on introducing patient-reported outcomes into renal services. In the week following the presentation, there have been requests for more information on the KRUK project from researchers from the Renal Research Institute (New York, US) and University of Sydney (Australia). |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://epidemionephro.com/nephrologie/contenu/patient-reported-outcomes-mise-en-place-au-royaume-uni |
| Description | Is mental health data more sensitive than physical health data debate |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | For each person affected by mental illness, approximately £8 is invested in mental health research while around £176 per sufferer is invested in cancer research - meaning that mental health research receives 22 times less funding than cancer research. But why is this the case, what can we do to change these figures and, importantly, could our health information hold the key to democratising research and if so, should this data be used? These questions catalysed The University of Manchester's Centre for Health Informatics to bring together experts from across research, the NHS & mental health charities to publicly debate the following; Do you agree that mental health data is no more sensitive than physical health data and that both should be used equally in data linkage research? The event was held at Central Library in Manchester and gained a lot of interest. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.herc.ac.uk/2018/03/08/mental-health-data-sensitive-physical-health-data/ |
| Description | Lancashire Science Festival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Schools |
| Results and Impact | #datasaveslives stall and immersive role play game 'A day in the life of data' at Lancashire Science Festival |
| Year(s) Of Engagement Activity | 2018 |
| Description | Learning population health systems - The role of local whole population linked datasets |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Other audiences |
| Results and Impact | Panel: Learning population health systems - The role of local whole population linked datasets with J George, I Buchan, M Bardsley, S Dougan and A George |
| Year(s) Of Engagement Activity | 2017 |
| Description | MICRA seminar on 'Using digital health technologies for ageing in community settings' |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | Seminar organised in collaboration with Manchester Institute for Collaborative Research on Ageing (MICRA), aimed at researchers and the general public. Sabine van der Veer developed the seminar agenda and will chair the meeting. People who participated in the Community Reporter project on senior citizens and health data have been invited, with some of them talking about their experiences with the project on stage. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://www.micra.manchester.ac.uk/connect/events/using-digital-health-technologies-for-ageing-in-com... |
| Description | MMPathIC - Engaging Engineers and Physical Scientists Workshop, Manchester |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Professional Practitioners |
| Results and Impact | MMPathIC - Engaging Engineers and Physical Scientists hosted by Prof Katherine Boylan, Manchester, July 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | MRP Advisory Group, London |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | MRP Advisory Group, London, August 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | MSDS Ltd Engagement |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | The HeRC Director was invited by MSDS Ltd to advise on statistical automation of reporting from the clinical audit databases the company runs. A predictive modelling project in haemophilia and provision of statistical learning tools and training materials for customers. |
| Year(s) Of Engagement Activity | 2013 |
| Description | Mail Online National News Piece: It's not in your mind - aches and pains really DO feel worse on damp and windy days, scientists find |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Mail Online Website Article on Cloudy with a chance of pain PI: Will Dixon It's not in your mind - aches and pains really do feel worse on damp and windy days, research suggests. Scientists asked almost 2,700 arthritis, migraine and fibromyalgia patients to report their pain every day for six months. The University of Manchester team used GPS data from the participants' phones to determine the weather for each day. Results showed patients were 20 per cent more likely to suffer pain on damp, windy days with low atmospheric pressure. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.dailymail.co.uk/health/article-7604741/Aches-pains-really-feel-worse-damp-windy-days.htm... |
| Description | Making Big Data "Actionable" |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Making Big Data "Actionable" at Manchester One, Manchester's NHS Innovation Expo. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Making a Difference Award for Public Patient Involvement Engagement activities |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Industry/Business |
| Results and Impact | HeRC's Patient and Public Involvement (PPI) group, H@PPI (HeRC@PPI), plays an integral role in developing and implementing our plans for public involvement and engagement. Since their formation in 2014, H@PPI's 12 public contributor have dedicated their time towards understanding and advising on HeRC's PPI activities, communications and research. The team have received won an Inspiring Communities award for research contirbution and outreach activities. They were highly Commended for their work. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.herc.ac.uk/get-involved/join-our-forum/ |
| Description | Making a Difference Highly Commended award for Britain Breathing research team |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | A team of researchers from The University of Manchester, the Royal Society of Biology and the British Society for Immunology have worked with people with seasonal allergies to design a new smartphone app that collects data on when and where allergy symptoms occur. #BritainBreathing aims to use the power of 'citizen science' to investigate these complex relationships to shed light on the causes of increases in allergies, whilst empowering citizens to understand and manage their own symptoms in the process. The app associated research has been showcased at various public events throughout the year i.e. Bluedot science festival. It has been highlighted in a range of mass media outlets i.e. the Guardian and BBC news. The group were highly commended at the making a difference awards for all their work. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://britainbreathing.org/ |
| Description | Manchester Day |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Manchester Day is an annual event which attracts around 70,000 visitors from all backgrounds. Each year Manchester day takes a new theme; this year it was 'Eureka!' to celebrate Manchester as European City of Science, in which Cloudy has been adopted as a citizen science project. The event connects artists, communities and scientists and allowed us to access people not usually interested in health research. The aims for participating in the event were: ? To raise awareness of arthritis and chronic pain conditions. ? To raise awareness of Cloudy with a Chance of Pain and increase recruitment. ? To raise awareness of the role that citizen scientists can play in research projects, with a specific focus on Cloudy. ? To build a visual representation of people's pain and raise awareness at how widespread arthritis and musculoskeletal pain conditions are by representing pain in a creative way. ? To highlight arts-science collaborations: making publically engaging art from scientific data. ? To enable people and their family/friends to discuss the impact of pain in their lives and to feel understood and heard (pain booth). Target of 20 people's stories recorded in audio, text and photographs. ? To collect people's pain stories in a creative way for use in Cloudy and ARUK media. Activities were: - Immersive Data Walkway: Our New York-based project partners, the Office for Creative Research (OCR), designed and constructed a physical representation of data collected from February 1st- 14th 2016 in the Manchester area. - Citizen Science touchscreens: to enable people to interact with the Cloudy citizen science experiment and find out more about the project by talking to the project team and volunteers. Visitors were able to leave comments, indicate whether they had learned more about the role of citizen science in research projects, and whether they were likely to join the study or submit hypotheses. - 'Arthur' the pain mannequin: an arts/science collaboration to create a beautiful and enormous articulated figure called Arthur, suspended within a 7m high rig (or 'pain prison'). The frame would act as a metaphor for pain, with the figure trapped within it. Members of the public were invited by 'weatherman' Michael Kipper to select a piece of fabric representing their pain levels over the past couple of weeks and post it on to the relevant body part of a smaller version of Arthur. - Pain Listening Booth: an activity designed and run by patients to enable people to share their experiences of living with chronic pain and make their 'invisible' pain visible. 1100 people actively engaged with our activities and we received many positive comments. |
| Year(s) Of Engagement Activity | 2016 |
| Description | Manchester's annual Caribbean Carnival |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | The #Datasaveslives team were out in full force on Saturday 12th August, engaging the public on the subject of health data and research at Manchester's annual Caribbean Carnival. Taking place in Moss Side's Alexandra Park the team from CHC partnered with the British Science Association, The University of Manchester's Public Programmes team and the National Grid in a one-day science spectacular. Working together under the banner of Blast Fest, an organisation who explore Science & Technology through Black Arts & Culture, HeRC/ CHC colleagues specifically discussed the reuse of health data in suitably tropical weather conditions: pouring rain followed by belting sunshine. Alongside some hands-on and family friendly activities the public participants were asked to vote on two questions related to the sharing and accessing health records |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.connectedhealthcities.org/2017/08/datasaveslives-mcr-caribbean-carnival/ |
| Description | Media coverage of Cloudy with a Chance of Pain from British Science Festival press conference |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Press conference held at the British Science Festival in September 2016 about some early findings uncovered by the Alan Turing Institute collaboration. The story was picked up by 38 different national/international press, radio and TV outlets. This led to over 3000 new recruits to the study and an increased awareness of the project and MSK conditions. |
| Year(s) Of Engagement Activity | 2016 |
| Description | MoMoMcr (Mobile Monday Manchester). Networking seminar. |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Public/other audiences |
| Results and Impact | The HeRC Research Programme Manager and Communications Lead have now made contact with the director of UKFast et al Communications Lead now in open dialogue and knowledge-sharing with Health 2.0. |
| Year(s) Of Engagement Activity | 2014 |
| Description | NCCPE annual conference in Bristol |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Other audiences |
| Results and Impact | The Public PatientInvolvement and Engagement team held a workshop at Engage 2017: Exploring Collaboration looked at collaboration and engagin with groups. Looking across the spectrum of collaborative approaches, it showcased cutting edge practice and shared the latest thinking from within higher education and beyond. |
| Year(s) Of Engagement Activity | 2017 |
| URL | https://www.publicengagement.ac.uk/sites/default/files/publication/engage_2017_lf_programme_v2.2.pdf |
| Description | NIB Working Group |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | NIB Working Group, London, May 2016 |
| Year(s) Of Engagement Activity | 2016 |
| Description | National Information Board Strategy Development Meeting |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | Yes |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Professor Buchan provided a written contribution to the National Information Board Strategy Chapter 5. This event was designed to allow policy makers, academics, and the public to review the draft strategy and inform revisions. This included a public panel discussion between policy makers and members of the H@PPI forum. Publication of the final strategy is anticipated in December 2014. The National Information Board Strategy will be revised on the basis of feedback from this meeting. |
| Year(s) Of Engagement Activity | 2014 |
| Description | National News Piece: Gloomy weather really does make arthritis more painful, study suggests : The Telegraph |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | Professor Will Dixon The telwegraph Online Article for Cloudy with a Chance of Pain Hippocrates, writing in 'On Airs, Waters, and Places', claimed those who wish to understand medicine need only look at the changing seasons of the year and study the prevailing winds. Now, 2,500 years later, a new study has found the Greek physician may have been on to something. Scientists have discovered that pain really does get worse on damp, dismal days, confirming what arthritis sufferers have long suspected |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.telegraph.co.uk/science/2019/10/23/gloomy-weather-really-does-make-arthritis-painful-stu... |
| Description | National newspaper coverage |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Articles about Cloudy with a Chance of Pain features in multiple national newspapers, both print and online editions. National papers included the Independent, The Mirror, Daily Express and Daily Mail. |
| Year(s) Of Engagement Activity | 2016 |
| URL | http://www.independent.co.uk/life-style/health-and-families/health-news/smartphone-app-could-help-un... |
| Description | New guidance being developed following public dialogue on health research |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | My work on simple pragmatic trials has led to the Health Research Agency initiating a public consultation of the expectations of consent in low risk trials, in which I also participated. Following the public dialogue project carried out with Sciencewise support at the end of 2014, the Health Research Authority (HRA) has been revising their Policy Framework for Health and Social Care Research prior to a formal consultation, following an informal call for comments earlier in the year. In addition the HRA has recently been developing guidance on two specific issues based on the input of the public and patient participants at the public dialogue: • The first set of guidance focuses on proportionate consent for simple pragmatic clinical trials. The HRA will be putting out their revised guidance on proportionate consent to formal consultation early next year. It is expected that the guidance will be finalised and launched in spring 2016. Prior to the formal consultation process, and in order to raise the profile of this issue among key stakeholders, the HRA is holding an event on 3rd December 2015 at Oxford Town Hall. Speakers will include Ben Goldacre, Iain Chalmers and Tjeerd van Staa (who all contributed to the dialogue). The HRA will be presenting the dialogue results at this event. • The second set of guidance focuses on how people are identified and recruited to take part in health research, which has implications in terms of access to patient records and shared data. The HRA has been developing draft guidance but this is currently on hold pending the completion of a Government review of consent led by Dame Fiona Caldicott. The findings of the review may impact on the drafting of the guidance, which will therefore be completed following the publication of the review report. The HRA dialogue report was published in June 2015 (see www.sciencewise-erc.org.uk/cms/assets/Uploads/HRA-IRPHR-Dialogue-Report-Final-June-24-3.pdf); the evaluation report is expected to be published soon. |
| Year(s) Of Engagement Activity | 2014,2015 |
| URL | http://www.sciencewise-erc.org.uk/cms/assets/Uploads/HRA-IRPHR-Dialogue-Report-Final-June-24-3.pdf |
| Description | Panel: Making a difference together: How can public involvement improve the relevance, acceptability, quality and impact of health informatics research? |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Other audiences |
| Results and Impact | Lamiece Hassan chaired a panel at the Informatics for Health Conference organised by the FARR Institute and HeRC. In the UK, public involvement in research is defined as research conducted 'with' or 'by' members of the public, rather than 'to', 'about' or 'for' them. This panel will review approaches to developing meaningful collaborations with patients, carers and members of the public to improve health informatics research. Researchers will present alongside public contributors to describe methods, challenges, impact and lessons learned within their projects. The audience will then be invited to join in discussions to explore how collaborative ways of working may be fostered to improve the quality, relevance, acceptability and impact of health informatics research. |
| Year(s) Of Engagement Activity | 2017 |
| URL | http://bqz75q.m.attendify.com/app/sessions/9JC88UMn0XgeB3bUBs/details |
| Description | Patient and Public Involvement in Social Pharmacy Research (18th International Social Pharmacy Workshop) |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | Presentation delivered at conference in Boston, USA. Contemporary approaches to patient and public involvement (PPI) in research means carrying out studies 'with' or 'by' members of the public (including patients, potential patients and carers) rather than 'to', 'about' or 'for' them. Such involvement is central to much health research policy. For example, the National Institute for Health Research in the UK and the Patient-Centered Outcomes Research Institute in the USA require meaningful PPI in applications to their funding programmes. PPI could bring into the research process, for example, the expertise of people living with a chronic disease for many years or the voices of taxpayers as the new treatments to be investigated by a national health service. Opportunity to communicate activities in PPI research to international audience. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Population Health Working Group, London |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Professional Practitioners |
| Results and Impact | Population Health Working Group, London |
| Year(s) Of Engagement Activity | 2016 |
| Description | Primary Care Research Improvement Event |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Other academic audiences (collaborators, peers etc.) |
| Results and Impact | Discussion identified a number of tangible ways in which the community of academic researchers and primary care professionals may better-collaborate on research grant applications and projects. Next steps are being defined. |
| Year(s) Of Engagement Activity | 2014 |
| Description | Royal Meteorological Society for Scotland talk |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Other audiences |
| Results and Impact | Talk to non-specialist audience (but generally well educated in meteorology and climatology): It is composed of amateur and professional meteorologists, both active and retired, together with researchers from other disciplines. Staff and students from the University of Edinburgh were also in the audience. Part of a regular series of talks. |
| Year(s) Of Engagement Activity | 2017 |
| Description | SKY NEWS Arthritis: Study discovers surprising link between chronic pain and weather |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | SKY News website piece - Professor Will Dixon from Cloudy with a Chance of Pain People with arthritis are more likely to feel pain on humid, windy days, according to new research. Scientists from the University of Manchester found sufferers were 20% more likely to be in pain on days that are humid and windy with low atmospheric pressure than on days with average weather. Funded by the charity Versus Arthritis, the study examined data from 2,658 people, who provided daily data on pain levels on most days for around six months. 24/10/2019 |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://news.sky.com/story/arthritis-study-discovers-surprising-link-between-chronic-pain-and-weathe... |
| Description | School Event at conference |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Schools |
| Results and Impact | Approx 50 pupils attended an event at the Farr Conference 2015, which included interactive sessions and information about careers in health informatics. |
| Year(s) Of Engagement Activity | 2015 |
| URL | |