MRC Centre for Outbreak Analysis and Modelling Renewal

Lead Research Organisation: Imperial College London
Department Name: School of Public Health

Abstract

The threat from new infectious diseases has been highlighted in recent years by the 2003 SARS epidemic, H5N1 'bird flu' and the 2009 H1N1 flu pandemic. Preparing for such eventualities is a priority for public health agencies and governments worldwide. Also, as scientific research delivers new approaches to controlling existing infectious diseases such as malaria, HIV and polio, there is a need to determine what interventions are likely to work best to limit the disease and illness caused by a specific disease in a particular setting.

In this context, computer modelling of the spread of diseases in populations coupled with scientifically rigorous data analysis have proven themselves as powerful tools for giving insight into how diseases spread and what can be done to limit that control that spread. The Centre for Outbreak Analysis and Modelling undertakes research on these scientific methods and applies them to disease threats of concern.

A key feature of the Centre is the close links it has made with with public health agencies - such as the UK Health Protection Agency, the Centers for Disease Control and Prevention in the US (CDC), and the World Health Organization (WHO) - organisations which have to formulate and implement strategies to control infectious diseases.

The senior scientists in the Centre are world-leaders in infectious disease modelling and analysis. They have broad experience in responding to real epidemics (e.g. BSE/vCJD, SARS, H5N1 bird flu and the 2009 flu pandemic), and undertaking epidemiological research on endemic diseases (such as malaria, HIV and polio). Their work directly influences disease control policy through the many interactions the Centre has with public health organisations and governments.

The funding provided by MRC and Imperial College have allowed dedicated investment into the development of close collaborative partnerships with HPA, CDC and WHO - as well as with other important organisations who work on improving health in developing countries (notably the Bill and Melinda Gates Foundation). With each, we are working on a large number of research projects which have both scientific interest to Centre researchers and are contributing to the evidence base needed for public health decisions. Centre funding supports a core technical capacity available to all projects, and pays for dedicated postdoctoral research staff who spend substantial time at WHO (Geneva) and CDC (Atlanta) undertaking epidemiological research with the staff of those agencies and facilitating collaboration with other Centre staff.

MRC funding has also facilitated a greater focus on collaboration, training and career development within the Centre - training the next generation of quantitative infectious disease epidemiologists. We are also involved in increasing knowledge of advanced modelling methods in public health institutions and the wider infectious disease research community, and so have run a number of introductory vocational short courses, both at Imperial College, but also on partner sites in Geneva and London.

All of this applied activity depends on the more fundamental research undertaken in the Centre on the epidemic dynamics of different diseases, how diseases evolve genetically over time, and on analysing new approaches to control or treat diseases. Much of this research is multidisciplinary, involving Centre researchers working with leading clinical and experimental scientists around the world.

Continued funding for the Centre will allow the collaborative partnerships established in the last 4 years to be sustained and enhanced, and new collaborations with researchers and health agencies in countries such as China and India to be developed. It will also fund new priority research areas, including work to implement the analysis and modelling methods developed by Centre staff as user-friendly computer programs that can be used by public health professionals around the world.

Technical Summary

The threat to human populations from new and re-emerging pathogens has been highlighted in recent years by the 2003 SARS epidemic, the pandemic potential of the highly pathogenic H5N1 avian influenza strain and the 2009 H1N1 pandemic. Preparedness is therefore a key policy priority for public health agencies and governments worldwide. In addition, as novel vaccines, antimicrobials and other interventions are developed for endemic diseases, there is a need to extrapolate from clinical trial results to determine which combination of interventions gives the optimal (or most cost-effective) control strategy for a specific disease in a particular setting.

In this context, modern epidemiological modelling and analysis methods have proven themselves increasingly powerful tools for giving insight into the patterns of emergence of novel outbreaks, the transmission dynamics of endemic diseases and the options available for the control of both. In the last 4 years, the Centre for Outbreak Analysis and Modelling has facilitated the exploitation of cutting-edge quantitative epidemiological research by public health agencies and policy makers tasked with delivering response strategies to infectious disease threats.

Before the founding of the Centre, much of the interaction between the (world leading) researchers at the Centre and public health agencies (such as HPA, CDC or WHO) was sporadic and unsystematic, being difficult to fund from traditional project grants. Centre funding allows dedicated investment into the development and maintenance of close collaborative partnerships with HPA, CDC, WHO and BMGF. Centre funding supports a core technical capacity available to all projects, and pays for dedicated 'liaison' staff - postdocs who spend substantial time at WHO and CDC. Internally, Centre funding supports capacity-building, enhanced collaboration and an enhanced focus on career development - as well as vocational training of staff in public/global health agencies.

Planned Impact

As a translational research Centre, a key aspect of our primary mission is wider impact. Our goal is to improve public and global health decision making in relation to infectious disease control through the use of advanced statistical and mathematical modelling methods, with a particular emphasis on novel emerging infections or rapidly spreading disease outbreaks. We believe the only effective way of delivering on this goal is to form long-term collaborative partnerships with the leading public and global health organisations world-wide, providing analytical support and capacity building for those partners.

The 2009 H1N1 pandemic provided a concrete test of this vision. In the first few weeks of the pandemic, the Centre's response team rapidly scaled to involve over 30 staff, with individual components being led by Centre PIs, coordinated by the Director.
From the translational perspective, some of the most critical roles were the staff who acted as liaisons with our key public health partners (especially WHO and CDC), spending much of 2009 embedded in those organisations.

The success of this approach in 2009 has led us to formalise and extended this 'embedding' model of building collaborative partnerships. Following the pandemic, the Centre became the WHO Collaborating Centre for Infectious Disease Modelling, with a senior research fellow acting as our primary liaison with WHO. We have adopted a similar model with US CDC, with another senior postdoctoral researcher from the Centre is based in Atlanta for the majority of his time.

HPA has considerable modelling capacity itself (two groups, in Colindale and Porton Down), so the nature of its relationship with the Centre is rather different. The Colindale modelling unit is now headed by Dr Peter White, who splits his time between HPA (80%) and the MRC Centre at Imperial (20%), providing a natural bridge between us. Collaborative work with the Colindale group has increased dramatically over the last few years. The Centre also collaborates with and advises the Microbial Risk Assessment group at Porton Down, most notably on bioterrorism related topics.

A second important aspect of the relationship is coordination of parallel research efforts: the UK Dept of Health (DH) often calls upon HPA for quantitative analysis, and increasingly the MRC Centre is being called upon to either peer review this work or provide alternative independent analyses. As HPA evolves to become Public Health England, we expect this role to become more important.

Over the first term of the Centre we have also built close relationships with a number of other key global/public health bodies: BMGF, UNAIDS, European CDC, China CDC (on pandemic influenza) being just a few. Our relationship with BMGF is of particular strategic importance - both as a funder of Centre research, but more importantly as a key stakeholder in global health decision-making. The Centre's work on polio, malaria, HIV, dengue and influenza has been influential in shaping BMGF investment decisions.

In addition to formal research outputs, often the most important value we give to these organisations is advice provided from a dynamical modelling perspective. This analytical advisory role is multifaceted: from improving situational awareness in crises, advising on likely impact of interventions, undertaking rapid assessments of severity and disease burden, and advising on improving surveillance, study design and data capture systems.

Capacity building within our partner organisation is another priority, through informal skills transfer and formal training. The former occurs as a natural result of the degree of interaction, and for the latter we have run short (2-3 day) short courses on infectious disease modelling for WHO in Geneva (in 2010) and for CDC in Atlanta (in 2011, in collaboration with Harvard).

Attached letters of support from HPA, CDC, WHO and BMGF highlight the public health impact of the Centre.

Organisations

Publications

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Aldridge RW (2015) 'Pre-entry screening for tuberculosis' commentary: authors' response. in Pathogens and global health

 
Guideline Title "Estimating direct and indirect protection from influenza vaccination in the USA" (forthcoming)
Description "Estimating direct and indirect protection from influenza vaccination in the USA" (forthcoming) for CDC (USA) containing information to be included in national messaging on vaccination
Geographic Reach National 
Policy Influence Type Citation in clinical guidelines
 
Description "The Costs to Patients and Health Services of six Patient Safety Incidents: Evidence from English Hospitals" (forthcoming paper) presented to the Department of Health (NHS England)
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description Advice to EU on H1N1 pandemic (ECDC, DG-SANCO)
Geographic Reach Europe 
Policy Influence Type Participation in advisory committee
 
Description Advice to UK DH on pandemic planning via 'SPI' advisory committee
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description Advice to UK DH on responding to the UK H1N1 pandemic
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description Advice to US govt (White House, HHS, CDC) on pandemic planning
Geographic Reach North America 
Policy Influence Type Participation in advisory committee
 
Description Advice to US govt (White House, HHS, CDC) on responding to the H1N1 pandemic
Geographic Reach North America 
Policy Influence Type Participation in advisory committee
 
Description Advice to the World Health Organisation on the H1N1 pandemic
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description Advised WHO HIV Guidelines Committees (2014)
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact The WHO HIV treatment guidelines changed.
 
Description April 2017: Netherlands, audit of modelling activity by RIVM (Dutch Public Health Agency)
Geographic Reach Europe 
Policy Influence Type Participation in a advisory committee
 
Description Attendance at WHO policy meetings on anitmicrobial resistance and HIV prevention
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description Attended Davos as one of three Imperial representatives (including Alice Ghast and Kieth Nions). Advice to policy makers
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a national consultation
Impact reputation (representing Imperial at global forum)
URL https://youtu.be/Ws2VcwRFEIE
 
Description Bill And Melinda Gates Strategy and Advisory Group
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Influenced the development of grant policy
 
Description Bovine TB Advice to DEFRA
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description CDC - Disease Severity
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description CHPR Serology Surveillance Flu Steering Group - 2013
Geographic Reach National 
Policy Influence Type Participation in advisory committee
Impact Improved information with which to choose influenza vaccine strategies
 
Description Cabinet Office Advisory Committee
Geographic Reach National 
Policy Influence Type Participation in advisory committee
 
Description Chair of UNAIDS HIV Reference Group (2014)
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact The methods were updated to improve the precision & accuracy of countries view on the epidemics to inform local deceison making.
URL http://www.epidem.org
 
Description Commissioner on Lancet Commission for Global Surgery - 2015
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Description Consise Steering Committee - 2013
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
Impact More accurate assesment of influenza burden.
 
Description Continuation from 2015 reporting on CRO work. Modelling being used to advocate for major policy shifts for TB control in the region, as used by WHO.
Geographic Reach Asia 
Policy Influence Type Membership of a guideline committee
 
Description Continue to have an impact on global polio policy
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
 
Description Continued engagement with UNAIDS leaderships TH
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
Impact _
 
Description Continued engagement with WHO leadership TH
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact _
 
Description Continued engagement with leadership at Bill & Melinda Gates Foundation TH
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
Impact not known
 
Description Continued engagment with the PEPFAR leadership TH
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
Impact re-orientation of budgeting priorities -- but this is confidential stuff currently
 
Guideline Title National Guideline on Treatment of Latent Tuberculosis Infection
Description Contribution to NICE (The National Institute for Health and Care Excellence) Guidance on TB - 2015
Geographic Reach National 
Policy Influence Type Citation in clinical guidelines
URL http://www.nice.org.uk/guidance/ng33/evidence/appendix-i-imperial-college-ltbi-treatment-report-30-a...
 
Description Contribution to WHO Report on the use of mass drug administration for malaria - 2015
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
 
Description Contributor to WHO research roadmap on Influenza
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact Co-chaired one stream of WHO's periodic review of global influenza research priorities
URL http://www.who.int/csr/research-and-development/r_d_blueprint_plan_of_action.pdf?ua+1
 
Description Contributor to WHO research roadmap on Zika
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact Informed short term public health research priorities for responding to the Latin American Zika epidemic
URL http://www.who.int/csr/research-and-development/r_d_zika_involvement/en/
 
Description Coordination of multi-country research on specific topics of interest to WHO (e.g. H1N1pdm infection) resulting in peer-reviewed publications MVK
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
 
Description Copenhagen Consensus -TB control in India
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
Impact not yet known
 
Description DEFRA - modelling
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description DH Flu colloquium led by SofS DH
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description DH Pandemic Influenza Scientific Advisory Group
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description Department of Health - SPI
Geographic Reach National 
Policy Influence Type Participation in advisory committee
 
Description Department of Health Ebola modelling group (2014)
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
Impact Provided expert advice on Ebola epidemic response in West Afica, and preparedness for the UK, to ensure that the UK Government is provided with a high standard of scientific advice to support the response in West Africa and preparedness for the UK.
 
Description Designing Phase III Trials for potential transmission blocking vaccines in malaria (2014)
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
 
Description Development of platform RECON learn
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description EYE strategy subgroup for risk assessment (with WHO)
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact EYE strategy subgroup for risk assessment (with WHO) - participation with other academics to provide advice (to policy makers) in WHO with the aim to influence policy and decision making
 
Description Economic evaluation of London TB Find & Treat service (DH)
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Membership of a guidance committee
URL http://www.bmj.com/site/video/findandtreat.xhtml
 
Description Economic modelling of TB in hard to reach groups
Geographic Reach National 
Policy Influence Type Participation in advisory committee
Impact _
 
Description Eliminating Yellow fever Epidemics (EYE) WHO meeting
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
URL http://www.who.int/csr/disease/yellowfev/eye-strategy/en/
 
Description Elimination Scenario Planning (WHO Country Guidance Document) - 2013
Geographic Reach Africa 
Policy Influence Type Influenced training of practitioners or researchers
URL http://www.who.int/malaria/publications/atoz/9789241507028/en/
 
Description Elimination Scenario Planning (WHO policy document) AG
Geographic Reach Africa 
Policy Influence Type Citation in other policy documents
 
Description Epi Et - and Field Epi Training Program (PHE/CDC courses).
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact Helping to redesign teaching modules for these courses
 
Description Estimating the epidemic potential of swine-origin H3N2v influenza virus - results presented during a briefing to the director of US CDC SC
Geographic Reach North America 
Policy Influence Type Gave evidence to a government review
 
Description Evaluation of the London TB Find and Treat Project
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Participation in advisory committee
Impact not known
 
Description Evidence Review Group on Malaria Burden Estimation (WHO Committee) - 2013
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
URL http://www.who.int/malaria/mpac/evidencereviewgroups/en/
 
Description Evidence Review Group on Malaria Burden Estimation (WHO committee) AG
Geographic Reach Africa 
Policy Influence Type Membership of a guidance committee
 
Description Global Fund - develop KPIs for GF
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Supported the Global Fund with the development of their Key Performance Indicators (KPIs)
 
Description Global Fund - secure agreement on GF investment case
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Support for the Global Fund on their investment decisions
 
Description Global Plan for Insecticide Resistance Management (GPIRM) - WHO AG
Geographic Reach Africa 
Policy Influence Type Citation in other policy documents
 
Description Global polio immunisation
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description H5N1 Surveillance & Monitoring in Poultry
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description Home Office - Security and Identity
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description IVCC talk - Bhatt - (relating to decisions) - budgeting vector control . Effect of interventions
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
 
Description India National TB programme - Modelling in Support of the National Strategic plan
Geographic Reach National 
Policy Influence Type Participation in a national consultation
Impact not known yet
 
Description Infectious disease modelling short course - 2013
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact Informed public health professionals: what infectious diseases modelling can and can not do; what its data requirements are; how to critically appraise models.
URL http://www.infectiousdiseasemodels.org/
 
Description Investment Case for Global Fund 2017
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact TBC
URL http://www.theglobalfund.org/documents/publications/other/Publication_InvestmentCase_Summary_en/
 
Description London TB Find and Treat service (Parliamentary Hearings)
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
URL http://www.publications.parliament.uk/pa/ld200809/ldhansrd/text/90630-0001.htm
 
Description MERS-CoV collaboration
Geographic Reach Multiple continents/international 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
Impact Improvements in survival, morbidity or quality of life re MERS Co-V.
 
Description MESA malERA Refresh Panel: Health Systems and Policy Research
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
URL http://www.malariaeradication.org/malera-refresh/health-systems-and-policy-research
 
Description MRC Methodology and Research Panel Membership - 2015
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Participation in a advisory committee
 
Description Malaria Policy Advisory Committee
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
 
Description Market and transmission dynamics for efficient procurement of second-line TB drugs (2014)
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
 
Description Measures of efficacy of anti-malaria interventions against malaria transmission
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
URL http://www.who.int/vaccine_research/malaria_malvac2010/en/index.html
 
Description Member of the Scientific Programme Committee (CROI 'Conference on Retroviruses and Opportunistic Infections' 2016 Boston) - 2015
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description Membership in Core WHO Committee on the use of ART (2015)
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
URL http://apps.who.int/iris/bitstream/10665/186275/1/9789241509565_eng.pdf?ua=1
 
Description Monitoring disappearence of polio type 2 globally, providing weekly analysis of data to "polio partners": Gates, WHO, CDC (April 2016)
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Description NERVTAG (New and Emerging Respiratory Virus Threats Advisory Group) - 2015
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Description NICE revision of guidelines for TB control
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
URL http://www.nice.org.uk/nicemedia/live/11978/56320/56320.pdf
 
Description NIH (Expert consultation on finding 'unknowing' HIV) - 2013
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact Improved regulatory environment in HIV.
 
Description National Measles and Polio Committee UK - 2013
Geographic Reach National 
Policy Influence Type Participation in advisory committee
 
Description National Pandemic Flu Service (report) - 2015
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description Norwegian National Institute of Public Health consultation on learning the lessons on Ebola -2015
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Description Numerous citations in UK DH, US DHHS and WHO planning documents
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
URL http://europepmc.org/abstract/MED/16642006
 
Description Older adult Polio vaccination & infection - 2013
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
Impact no information
 
Description Outbreak response for yellow feevr in Angola
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
URL http://apps.who.int/iris/bitstream/10665/246103/1/WHO-YF-ENB-16.2-eng.pdf
 
Description PHE influenza partnership: The impact of mathematical modelling of influenza: better decisions for Public Health (2015)
Geographic Reach Europe 
Policy Influence Type Participation in a advisory committee
 
Description Paper (PMID: 26093978) on new vaccine strategies to finish polio eradication led to introduction of vaccine campaigns by Global Polio Eradication Programme in Nigeria, Pakistan and Afghanistan
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
 
Description Participation in evidence review group at the World Health Organization.
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
URL http://www.who.int/malaria/mpac/mpac-oct2017-erg-malaria-low-density-infections-session2.pdf?ua=1
 
Description Participation to the JMM (Joint Monitoring Mission) for the National Tuberculosis Programme assessment in India. Report availbale here: http://www.tbonline.info/media/uploads/documents/jmmdraft2015.pdf
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
URL http://www.tbonline.info/media/uploads/documents/jmmdraft2015.pdf
 
Description Polio immunisation plans
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
URL http://www.polioeradication.org
 
Description PopART (citation in new WHO consolidated treatment and testing guidelines) - 2013
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
URL http://www1.imperial.ac.uk/departmentofmedicine/divisions/infectiousdiseases/infectious_diseases/hiv...
 
Description Preparatory Meeting of the Global Fund Fifth Replenishment (2017-2019), 16-17 December 2015
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Guideline Title Conditions for use of long-lasting insecticidal nets treated with a pyrethroid and piperonyl butoxide
Description Presentation to WHO Expert Review Group on Bednets - 2016
Geographic Reach Africa 
Policy Influence Type Citation in clinical guidelines
Impact It is estimated that 68% of malaria deaths have been averted through use of bednets though there is increasing fear that the effectiveness of these nets is being reduced by the presence of mosquitoes resistant to insecticide. A new type of net is available that claims to overcome the problems of pyrethroid resistance but it much more expensive so it is unclear where and when control programmes should invest in this type of net. Our work was used to justify the current WHO policy for the use of these nets.
URL http://www.who.int/malaria/publications/atoz/use-of-pbo-treated-llins-report-nov2015.pdf?ua=1
 
Description Presented evidence for US National Academy of Science on the risks and benefits of gain-of-function experiments - 2015
Geographic Reach North America 
Policy Influence Type Participation in a national consultation
 
Description Providing direct technical support to Pakistan Ministry of Health and WHO
Geographic Reach Asia 
Policy Influence Type Participation in a national consultation
Impact Working with WHO and government offices to offer risk assessment and campaign planning for polio eradication
 
Description Provision of malaria vaccine public health impact scenarios to WHO and GAVI - 2013
Geographic Reach Africa 
Policy Influence Type Citation in other policy documents
 
Description Publication of journal article on increase to TB burden. Influencing global numbers and strategy
Geographic Reach Multiple continents/international 
Policy Influence Type Gave evidence to a government review
Impact Significant influence on global understanding of TB burden
URL http://timesofindia.indiatimes.com/india/No-of-Indias-TB-patients-may-be-double-the-estimate-Lancet/...
 
Description RCUK - Global Uncertainties
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description Recommendation for the long-term vaccination strategy for YF informing SAGE decisions
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
 
Description Roundatable to discuss Bovine Tuberculosis with Michael Gove, MP Defra Secretary of State and George Eustice, MP Minister, Jan 2018 (Department of Environment Food and Rural Affairs)
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
 
Description SPI (Scientific Pandemic Influenza advisory committee) - 2013
Geographic Reach National 
Policy Influence Type Participation in advisory committee
Impact Provided expert advice on influenza pandemic planning and response, to ensure that the UK Government is provided with a high standard of scientific advice to support planning and response to a pandemic in the UK, which is identified in the National Risk Register of Civil Emergencies as one of the 4 highest priority risks.
 
Description SPI-M (Scientific Pandemic Influenza advisory committee: Modelling subcommittee) - 2013
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
Impact Provided expert advice on influenza pandemic planning and response, to ensure that the UK Government is provided with a high standard of scientific advice to support planning and response to a pandemic in the UK, which is identified in the National Risk Register of Civil Emergencies as one of the 4 highest priority risks.
URL https://www.gov.uk/government/groups/scientific-pandemic-influenza-subgroup-on-modelling
 
Description Scientific Committee for Advanced Data and Modelling - 2013
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact Improved outbreak response policies for pandemic influenza.
URL http://www.chp.gov.hk/en/sas2/101/110/108.html
 
Description Seasonal Malaria Chemoprophylaxis (WHO policy document) AG
Geographic Reach Africa 
Policy Influence Type Citation in other policy documents
 
Description Serological Epidemiology of Influenza Steering Group - Health protection Agency
Geographic Reach National 
Policy Influence Type Participation in advisory committee
 
Description Severity of influenza pandemics. To feed into WHO guidelines on influenza severity.
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
URL http://www.who.int/influenza/en/
 
Description Sitting on the advisory committee of GORN. To inform and guide development of new tools for outbreak response
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact collaboration on tool development
 
Description Source of scientific data on the impacts of badger culling CD
Geographic Reach National 
Policy Influence Type Membership of a guidance committee
 
Description Sources of HIV transmission in The Netherlands
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact Improved knowledge amongst professional practitioners about the sources of HIV transmission in The Netherlands, which subsequently led to improvements in treatment, access to care, survival, morbidity and quality of life for people living with HIV in The Netherlands
 
Description Spi-M committee
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
Impact contribution to government Spi-M panel
URL https://www.gov.uk/government/groups/scientific-pandemic-influenza-subgroup-on-modelling
 
Description Stop TB Partnership (provision of advice for Global Drug Facility Committee) - 2013
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
Impact no information
 
Description Study made with PHE on allocation of pre-exposure prophylaxis for HIV
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
Impact Study made with PHE on allocation of pre-exposure prophylaxis for HIV
 
Description Technical assistance to WHO for WHO documentation (e.g., Weekly Epidemiologic Record publications) MVK
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
 
Description Technical expertise on WHO led teleconferences for influenza, yellow fever, meningitis, and other pathogens
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
Impact information not provided
 
Description The International Decision Support Initiative (iDSI) supprted by Bill & Melinda Gates Foundation
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Description Towards the Elimination of Hepatitis B and C by 2030. The draft WHO Global Hepatitis Strategy, 2016-2021 and global elimination targets.
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
 
Description Transmission Study Working Group for DEFRA on efficacy of BCG vaccination for cattle - 2015
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
 
Description Uptake of new molecular diagnostic tools for TB in India (2014)
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
 
Description WHO - Malaria Interventions
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description WHO - Public Health Research Priority for Influenza
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Description WHO - Technical Expert Group on Guideline Development
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Sought to influence the way WHO developed guidelines
 
Description WHO CONSULTATION ON INFLUENZA DISEASE BURDEN (External Expert) (December 2014)
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
 
Description WHO Collaboration on Modelling Dengue Vaccines - Strategic Advisory Group of Experts (SAGE) - 2015
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Description WHO Consultation on data sharing during public health emergencies; later included in WHO Guidelines on data sharing -2015
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Description WHO Consultations on 2013 HIV testing and treatment guidelines CF
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description WHO Ebola Response Group - 2014
Geographic Reach Africa 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
Impact Improvements in survival, morbidity or quality of life re Ebola.
URL http://www.nejm.org/doi/full/10.1056/NEJMoa1411100?query=featured_home
 
Description WHO Flu Burden (2014)
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact Improved methodology for measuring the burden of influence and hence maker better policy decisions.
URL http://www.who.int/immunization/topics/influenza/en/
 
Description WHO Gave evidence to 7th Vector Control Advisory group - VCAG
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
 
Description WHO Gave evidence to the World Health Organisation Expert Review Group on "Conditions for use of long-lasting insecticidal nets treated with a pyrethroid and piperonyl butoxide"
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
URL http://www.who.int/malaria/publications/atoz/use-of-pbo-treated-llins/en/#202017
 
Description WHO Global Technical Strategy Steering Committee - 2013
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
URL http://www.who.int/malaria/areas/global_technical_strategy/en/
 
Description WHO Global Technical Strategy for Malaria, 2016-2030 (2015)
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact http://www.who.int/malaria/areas/global_technical_strategy/en/; http://www.who.int/malaria/areas/global_technical_strategy/WHO_HTM_GMP_2014.11_eng.pdf?ua=1;
URL http://www.who.int/malaria/areas/global_technical_strategy/en
 
Description WHO HIV treatment committee - 2013
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
Impact WHO HIV treatment guidelines changed.
 
Description WHO Malaria Elimination Guidelines - 2014
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
URL http://www3.imperial.ac.uk/newsandeventspggrp/imperialcollege/newssummary/news_12-6-2014-18-17-49
 
Description WHO Policy Recommendation for the RTS,S malaria vaccine (2015)
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
URL http://www.who.int/immunization/policy/position_papers/malaria/en
 
Description WHO SAGE Polio - 2013
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in advisory committee
 
Description WHO and Wellcome Trust Joint Consultation on preparing for the next epidemic -2015
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Description WHO public health research agenda for Influenza. Speaker for the modelling stream of these guidelines
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
 
Description WHO recommnedations on 'Conditions for use of long-lasting insecticidal nets treated with a pyrethroid and piperonyl butoxide' (December 2015)
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
URL http://www.who.int/malaria/publications/atoz/use-of-pbo-treated-llins-report-nov2015.pdf?ua=1
 
Description Work Foundation panel discussion on assessing work productivity of people working with HIV/AIDS.
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Participation in a advisory committee
Impact Economic
URL http://theworkfoundation.com
 
Description Work Informing a government-planned field trial of BCG cattle vaccine. 2013
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description World Health Organisation Steering Committee for Global Malaria Technical Strategy - 2015
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
URL http://www.who.int/malaria/areas/global_technical_strategy/steering_committee/en
 
Description Yes - Ebola outbreak response in DRC
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
 
Description Zoonoses Workshop - Tanzania - Feb 2016 - 25 attendees including policy makers
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description polio1 NG
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
 
Description polio2 NG
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guidance committee
 
Description the Bovine TB Science Review Group, Wales
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Participation in a national consultation
 
Description vCJD projections and modelling
Geographic Reach National 
Policy Influence Type Participation in advisory committee
 
Description A genealogical approach to tracking bacterial transmission (Xavier Didelot)
Amount £403,170 (GBP)
Funding ID MR/N010760/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 05/2016 
End 05/2019
 
Description AMZAC (Azithromycin for Seasonal Malaria Chemoprevention) (Lesong Conteh)
Amount £146,860 (GBP)
Funding ID ITDCZA2510 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2014 
End 06/2017
 
Description An integrated approach to understand the emergence and spread of extensively resistant Gram-negative bacteria in China
Amount £26,958 (GBP)
Funding ID MR/P007597/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 07/2016 
End 08/2019
 
Description Analytic and sequencing tools for poliovirus environmental surveillance
Amount £554,669 (GBP)
Funding ID OPP1171890 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 05/2017 
End 05/2019
 
Description Assessing the impact of waning vaccine efficacy on malarial elimination using a population transmission model (Tom Churcher)
Amount £61,597 (GBP)
Organisation PATH 
Department PATH Malaria Vaccine Initiative
Sector Charity/Non Profit
Country Global
Start 10/2016 
End 11/2018
 
Description BBSRC: Analytical methodology to perform genome-wide association studies in bacteria (Xavier Didelot)
Amount £170,226 (GBP)
Funding ID BB/L023458/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 11/2014 
End 10/2016
 
Description BGMF: Mathematical modelling of poliovirus transmission to support the endgame
Amount £487,817 (GBP)
Funding ID OPP1099374 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2013 
End 04/2018
 
Description BGMF: Treat children in India for enteric infections to improve their response to oral poliovirus vaccine (expanded grant)
Amount £1,890,389 (GBP)
Funding ID OPP1039135 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 05/2012 
End 03/2017
 
Description BMGF HIV Modelling Consortium
Amount £2,080,207 (GBP)
Funding ID OPP1022972 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 09/2010 
End 09/2013
 
Description BMGF Malaria in Pregnancy (MiP) Consortium: Mathematical models to guide treatment and prevention strategies for P.falciparum malaria in pregnancy
Amount £81,332 (GBP)
Funding ID GATES FDN CONSORTIUM 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2010 
End 10/2014
 
Description BMGF Project Grant: Vaccine Modelling Initiative (VMI)
Amount £1,755,066 (GBP)
Funding ID 705580-1 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 04/2008 
End 10/2014
 
Description BMGF Project Grant: Vaccine Modelling Initiative (VMI) 2
Amount £958,185 (GBP)
Funding ID OPP1092240 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 06/2013 
End 06/2019
 
Description BMGF: Application of mathematical models to guide and evaluate malaria control and elimination programs
Amount £2,279,919 (GBP)
Funding ID OPP1068440 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 04/2013 
End 12/2019
 
Description BMGF: Control of TB in India: developing analytical tools
Amount £385,936 (GBP)
Funding ID OPP1095710 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2013 
End 10/2018
 
Description BMGF: HIV Modelling Consortium (renewal 2013)
Amount £3,522,615 (GBP)
Funding ID OPP1084364 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 06/2013 
End 07/2018
 
Description BMGF: Phylogenetics Networks to Address Transmission of HIV (PANGEA_HIV)
Amount £226,449 (GBP)
Funding ID OPP1084352 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2013 
End 09/2017
 
Description BMGF: PreP - ARV-based HIV Prevention Technologies
Amount £786,465 (GBP)
Funding ID OPP1032254 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2011 
End 10/2015
 
Description BMGF: The interaction between hormonal contraceptives and HIV risk
Amount £331,798 (GBP)
Funding ID OPP1067133 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2012 
End 02/2015
 
Description BMGF: Treat children in India for enteric infections to improve their response to oral poliovirus vaccine
Amount £61,482 (GBP)
Funding ID OPP1036117 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 05/2011 
End 10/2013
 
Description Building International Collaborations on the Mathematical Modelling of Emerging Infectious Disease Threats (Neil Ferguson)
Amount £49,657 (GBP)
Funding ID P11329/DF118 
Organisation Imperial College London 
Department Imperial College Trust
Sector Charity/Non Profit
Country United Kingdom
Start 04/2008 
End 12/2020
 
Description Building TRUST
Amount £100,609 (GBP)
Funding ID Sub Award No. 1800014 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 07/2015 
End 06/2018
 
Description CAPS (Cooking and Pneumonia Study) (Lesong Conteh)
Amount £24,526 (GBP)
Funding ID MR/K006533/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 09/2013 
End 02/2017
 
Description CDC via Uni Mississippi Med Center: Applied research to address emerging public health priorities BAA FY2017-OADS-01 (Xavier Didelot)
Amount £13,393 (GBP)
Funding ID 66109970918 
Organisation Centers for Disease Control and Prevention (CDC) 
Sector Public
Country United States
Start 09/2017 
End 09/2018
 
Description Cost-effectiveness systematic screening and treatment of pregnant women by CHW (Lesong Conteh)
Amount £167,022 (GBP)
Funding ID 305662 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 09/2012 
End 05/2017
 
Description DFID/MRC/Wellcome Trust Joint Global Health Trials Scheme
Amount £179,101 (GBP)
Funding ID RF020305 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 11/2014 
End 10/2018
 
Description DH: EMIT
Amount £94,640 (GBP)
Funding ID RGS:103272 
Organisation Department of Health (DH) 
Sector Public
Country United Kingdom
Start 09/2011 
End 09/2014
 
Description DH: Effectiveness for Testing for and Treatment for Latent TB (HALT Study)
Amount £210,090 (GBP)
Funding ID 015/0306 
Organisation Department of Health (DH) 
Sector Public
Country United Kingdom
Start 11/2012 
End 06/2017
 
Description DH: Improving communication with the public about antivirals and vaccination during the next pandemic
Amount £89,147 (GBP)
Funding ID N/A 
Organisation Government of the UK 
Sector Public
Country United Kingdom
Start 06/2013 
End 08/2015
 
Description Defining disease importation and target interventions from routine surveillance data (Tom Churcher)
Amount £81,703 (GBP)
Funding ID OPP1161898 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2016 
End 04/2018
 
Description Defra: A study to examine the interactions between cattle and badgers.
Amount £24,636 (GBP)
Funding ID ZSL ref: N587 
Organisation Department For Environment, Food And Rural Affairs (DEFRA) 
Sector Public
Country United Kingdom
Start 04/2012 
End 03/2015
 
Description Defra: Ecological and epidemiological effects of small-scale badger culling.
Amount £15,733 (GBP)
Funding ID SE3272 
Organisation Department For Environment, Food And Rural Affairs (DEFRA) 
Sector Public
Country United Kingdom
Start 09/2011 
End 03/2013
 
Description Defra: Transmission modeling and cost-effectiveness analysis of cattle vaccination at a herd level
Amount £481,855 (GBP)
Funding ID SE3130 
Organisation Department For Environment, Food And Rural Affairs (DEFRA) 
Sector Public
Country United Kingdom
Start 09/2011 
End 07/2014
 
Description Develop a novel, cost-effective, surveillance approach for malaria elimination through existing antenatal care platform
Amount £56,962 (GBP)
Funding ID GAT.2162-01585030-SUB 
Organisation PATH 
Sector Private
Country Global
Start 02/2018 
End 08/2018
 
Description Diversity and Phenotype of Artemisinin Resistance Mutations in Central Africa (AZra Ghani)
Amount £13,785 (GBP)
Funding ID 5104760 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 06/2016 
End 05/2018
 
Description Dorothy Hodgkin Fellowship - Lucy Okell (Modelling the control of artemisinin-based antimalarial drug resistance)
Amount £355,171 (GBP)
Funding ID N/A 
Organisation The Royal Society 
Sector Academic/University
Country United Kingdom
Start 01/2016 
End 12/2020
 
Description EMPIRIE: European managment platform for emerging and re-emerging infectious diseases entities.
Amount £890,687 (GBP)
Funding ID 223498 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 05/2009 
End 04/2014
 
Description ERC: BEEHIVE (Bridging the Evolution and Epidemiology of HIV in Europe)
Amount £2,261,061 (GBP)
Funding ID 339251 
Organisation European Research Council (ERC) 
Sector Public
Country European Union (EU)
Start 04/2014 
End 03/2019
 
Description EU FP7: PREHDICT: Health Economic Modelling of PREvention Strategies for HPV-related diseases in European Countries
Amount £301,527 (GBP)
Funding ID 242061 
Organisation European Commission 
Department Seventh Framework Programme (FP7)
Sector Public
Country European Union (EU)
Start 05/2010 
End 04/2013
 
Description EU FP7:PREDEMICS
Amount £780,182 (GBP)
Funding ID 278433 
Organisation European Commission 
Department Seventh Framework Programme (FP7)
Sector Public
Country European Union (EU)
Start 11/2011 
End 10/2016
 
Description EU: Building an Integrated Genetic infectious disease epidemilogy approach (transferred to UCL)
Amount £80,930 (GBP)
Funding ID 260801-BIG_IDEA 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 11/2010 
End 12/2015
 
Description Epidemiological analysis and mathematical modelling of poliovirus elimination and endgame vaccination strategies
Amount £56,616 (GBP)
Funding ID 2017/769688-0 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 11/2017 
End 12/2017
 
Description Epidemiology, evolution and control of infectious (AZra Ghani)
Amount £200,400 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2017 
End 09/2023
 
Description Epstein Barr Virus: Many questions, few answers
Amount £2,800 (GBP)
Funding ID 536857 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2016 
End 01/2018
 
Description Evolution, transmission and diversification patterns of group B streptococci - Elita Jauneikaite Fellowship
Amount £125,000 (GBP)
Funding ID M683 
Organisation Rosetrees Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2017 
End 10/2021
 
Description Evolution, transmission and diversification patterns of group B streptococci - Elita Jauneikaite Fellowship
Amount £125,000 (GBP)
Funding ID M683 
Organisation Stoneygate Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2017 
End 10/2021
 
Description Gates: Modelling the impact of diagnostics in global health: The BMGF Diagnostics Consortium
Amount £403,372 (GBP)
Funding ID OPP1095124 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2013 
End 02/2015
 
Description Geospatial modelling for malaria risk stratification and intervention targeting (Sam Bhatt)
Amount £219,507 (GBP)
Funding ID 1606H5002/JH6 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 09/2016 
End 08/2020
 
Description H99: IHI iSense internal funding. Digital Disease Detection.
Amount £99,210 (GBP)
Funding ID 161737 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start 02/2016 
End 04/2017
 
Description HC-HIV modeling activity
Amount £156,940 (GBP)
Organisation United States Agency for International Development 
Sector Public
Country United States
Start 06/2017 
End 06/2018
 
Description HIV Prevention Trials Network (HPTN)
Amount $784,089 (USD)
Funding ID UM1 AI068619 
Organisation FHI 360 
Sector Charity/Non Profit
Country United States
Start 03/2015 
End 11/2018
 
Description HMJF: Influenza severity in the US military/CONSISE
Amount £125,923 (GBP)
Funding ID Contract No. 775696 
Organisation Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF) 
Sector Academic/University
Country United States
Start 01/2013 
End 09/2013
 
Description HPA: Evaluation of the TB Find and Treat Project
Amount £129,932 (GBP)
Funding ID DoH via HPA 
Organisation Department of Health (DH) 
Sector Public
Country United Kingdom
Start 12/2010 
End 07/2017
 
Description Health economics of MDR TB testing in the UK - 2013
Amount £48,496 (GBP)
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 10/2012 
End 12/2013
 
Description IVCC (Liverpool School of Tropical Medicine and Hygiene)
Amount £166,330 (GBP)
Organisation Liverpool School of Tropical Medicine 
Sector Academic/University
Country United Kingdom
Start 06/2015 
End 08/2017
 
Description Identification of factors promoting the emergence of pathogens with human pandemic potential with zoonotic backgrounfd and related prevention strategies
Amount £759,182 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 11/2011 
End 04/2017
 
Description Impact of maternally derived antibodies and microbiota on the immunogenicity of rotavirus vaccines in African, Indian and European infants
Amount £204,213 (GBP)
Funding ID JXR11990 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 07/2015 
End 07/2018
 
Description Imperial College Global Health Fellowship Scheme: Integration of Communicable and Infectious Disease Health Care in South Africa (Berkowitz, Natasha)
Amount £70,409 (GBP)
Funding ID 105603/Z/14/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2016 
End 08/2017
 
Description Imperial College Global HealthClinical Fellowship Scheme: Understanding HIV Epidemics, Disease Progression and Interventions towards Marginalised (Kyaw Min, Soe)
Amount £58,967 (GBP)
Funding ID 204834/Z/16/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2017 
End 06/2018
 
Description Imperial College JRF: The effects of mass drug administration on Schistosoma population dynamics (Poppy Lamberton)
Amount £180,000 (GBP)
Organisation Imperial College London 
Sector Academic/University
Country United Kingdom
Start 12/2012 
End 11/2015
 
Description Improving Delivery of HIV Prevention and Treatment through Implementation Science and Translational Research (R01)
Amount $754,023 (USD)
Funding ID 1R01AI120913-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 07/2015 
End 06/2016
 
Description Improving the efficacy of malaria prevention in an insecticide resistant Africa (Tom Churcher)
Amount £162,798 (GBP)
Funding ID 200222/B/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2016 
End 04/2019
 
Description Juior Research Fellowship - Hannah Slater (Modelling the spatial heterogeneity of malaria transmission and the impact of spatially targetted interventions to eliminate malaria)
Amount £142,150 (GBP)
Organisation Imperial College London 
Sector Academic/University
Country United Kingdom
Start 10/2016 
End 09/2019
 
Description Junior Research Fellowship - Ilaria Dorigatti (Within-host dynamics of dengue virus pathogenesis and the human antibody response)
Amount £150,510 (GBP)
Organisation Imperial College London 
Sector Academic/University
Country United Kingdom
Start 10/2015 
End 09/2018
 
Description Junior Research Fellowship - Rafal Mostowy (Understanding the contribution of horizontal exchange of genes to the evolution of antigenic diverity in bacteria)
Amount £139,790 (GBP)
Organisation Imperial College London 
Department Imperial College Trust
Sector Charity/Non Profit
Country United Kingdom
Start 10/2016 
End 09/2019
 
Description Laboratory Refurbishment Award
Amount £249,139 (GBP)
Organisation The Royal Society 
Sector Academic/University
Country United Kingdom
Start 03/2017 
End 12/2017
 
Description MIDAS 2: Models for synthesising molecular, clinical and epidemiological data, and translation to public health response (NIH)
Amount £1,371,391 (GBP)
Funding ID 1U01GM110721-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2014 
End 05/2019
 
Description MIDAS Project with UC San Diego AntiViral Research Center (AVRC)
Amount £38,355 (GBP)
Funding ID 58214101 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 05/2014 
End 05/2016
 
Description MIDAS: Modelling Epidemic Infectious Diseases Using Sequence Analysis (Erik Volz)
Amount £184,667 (GBP)
Funding ID 258162IMP 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 01/2016 
End 05/2019
 
Description MMV: Modeling of different potential implementations of existing ACTs and other anti-malarial products in development."
Amount £316,782 (GBP)
Funding ID MMV AD-12-1400-03 
Organisation Medicines for Malaria Venture (MMV) 
Sector Charity/Non Profit
Country Switzerland
Start 10/2013 
End 09/2016
 
Description MRC Centre Grant: Centre for Outbreak Analysis and Modelling
Amount £1,933,493 (GBP)
Funding ID G0600719 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2008 
End 03/2013
 
Description MRC Centre Grant: Centre for Outbreak Analysis and Modelling (Renewal)
Amount £2,092,163 (GBP)
Funding ID MR/K010174/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2013 
End 03/2018
 
Description MRC Centre Grant: Centre for Outbreak Analysis and Modelling - equipment supplement
Amount £141,000 (GBP)
Funding ID MR/K010174/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2014 
End 03/2015
 
Description MRC Centre Renewal - Equipment Sub # 2
Amount £100,000 (GBP)
Funding ID MR/K010174/1B 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2013 
End 03/2018
 
Description MRC Fellowship - Bob Verity (Genetic data as a signal of changing malaria transmission)
Amount £281,370 (GBP)
Funding ID MR/N01507X/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2016 
End 03/2019
 
Description MRC Fellowship - Michael White (Modelling the contribution of relapse infections to the epidemiology and control of Plasmodium vivax malaria)
Amount £300,098 (GBP)
Funding ID MR/L012170/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2014 
End 02/2017
 
Description MRC Fellowship - Patrick Walker (Understanding trends towards malaria elimination in Western Kenya)
Amount £299,834 (GBP)
Funding ID MR/L012189/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2014 
End 03/2017
 
Description MRC Fellowship: Assessing the impact of HIV-1 in the black Caribbean community in south London
Amount £368,031 (GBP)
Funding ID G0802431/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2009 
End 09/2013
 
Description MRC Fellowship: Optimal trial design for a release of malaria-refractory transgenic mosquitoes (John Marshall)
Amount £285,102 (GBP)
Funding ID MR/J012254/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2012 
End 09/2015
 
Description MRC Fellowship: Spatio-temporal dynamics of drug-resistant Plasmodium falciparum malaria in Africa: implications for public health (Lucy Okell)
Amount £305,791 (GBP)
Funding ID G1002387 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 09/2011 
End 09/2015
 
Description MRC Fellowship: Synthesising data from multiple spatial scales and levels of detail to improve malaria transmission model predictions (Jamie Griffin)
Amount £418,907 (GBP)
Funding ID G1002284 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 09/2011 
End 09/2015
 
Description MRC Methodology Fellowship K O'Reilly - 2013 (Development of statistical modelling framework to inform real-time immunization strategies for elimination of poliomyelitis and other diseases)
Amount £407,785 (GBP)
Funding ID MR/J014362/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2012 
End 09/2016
 
Description MRC Methodology Fellowship: Understanding the spatial dynamics of poliomyelitis and improved planning and mass vaccination campaigns.
Amount £407,784 (GBP)
Funding ID MR/J14362/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2012 
End 09/2016
 
Description MRC Population Health Science Fellowship: Evaluation of Interventions and Diagnostics of Neglected tropical Diseases in sub-Saharan Africa
Amount £326,242 (GBP)
Funding ID G0902130 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 09/2010 
End 08/2013
 
Description MRC Supplement to MRC Centre Award: A continental-scale simulator for modelling malaria eradication strategies
Amount £280,558 (GBP)
Funding ID G0600719 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2009 
End 03/2013
 
Description MRC fellowship JM - 2013
Amount £285,102 (GBP)
Funding ID MR/J012254/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2012 
End 09/2015
 
Description MRC: Centre for Outbreak Analysis and Modelling - studentships
Amount £360,512 (GBP)
Funding ID 1U54GM088491-01 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2013 
End 03/2019
 
Description MRC: Understanding herd immunity and incidence variation for rapidly evolving pathogens: influenza in England and Wales, 1986 to 2009
Amount £839,354 (GBP)
Funding ID MR/J008761/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 11/2013 
End 05/2017
 
Description Mapping the risk of international infectious disease spread
Amount £111,089 (GBP)
Funding ID AID-OAA-F-16-00115 
Organisation United States Agency for International Development 
Sector Public
Country United States
Start 10/2016 
End 06/2018
 
Description Marie Curie Fellowship - Francois Blanquart (Predicting the evolution of resistance in streptococcus pneumoniae - H2020)
Amount £144,781 (GBP)
Funding ID 657768 
Organisation Marie Curie 
Department Marie Curie Research Institute
Sector Academic/University
Country United Kingdom
Start 06/2015 
End 05/2017
 
Description Marie Curie Fellowship - Rafal Mostowy (The role of recombination in the evolution and epidemiology of the bacterial pathogen streptoccus pneumoniae)
Amount £164,152 (GBP)
Funding ID 329515 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 04/2013 
End 03/2015
 
Description Maternal Flu Immunisation CRA
Amount £7,004 (GBP)
Funding ID EPIDZC14 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 10/2013 
End 08/2014
 
Description Maximising the public health impact of new approaches to control malaria in pregnancy through the translation of evidence-based global policies to country level policies and plans.
Amount £42,075 (GBP)
Funding ID CSA-2014-276 
Organisation Sixth Framework Programme (FP6) 
Department European and Developing Countries Clinical Trials Partnership
Sector Public
Country European Union (EU)
Start 01/2016 
End 12/2018
 
Description Modeling to Understand the Epidemiological Impact and Market Impact of Harmonized Regimens for MDR-TB
Amount £30,828 (GBP)
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 07/2014 
End 03/2016
 
Description Modelling antimalarial target product profiles for reducing P. falciparum malaria transmission
Amount £316,782 (GBP)
Funding ID PO14/00561 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2013 
End 02/2019
 
Description Modelling malaria transmission and control in the Democratic Republic of Congo (NIH-UNC)
Amount £169,020 (GBP)
Funding ID 5101262 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 04/2015 
End 03/2019
 
Description Modelling the incremental value of alternative strategies to IPT for malaria in pregnancy
Amount £38,527 (GBP)
Organisation Jhpiego 
Sector Charity/Non Profit
Country United States
Start 01/2015 
End 08/2015
 
Description Modelling the potential impact of intermittent preventive treatment of malaria in pregnancy on antimalarial drug resistance
Amount £99,998 (GBP)
Organisation Royal Society of Medicine 
Sector Learned Society
Country United Kingdom
Start 12/2016 
End 08/2018
 
Description Multidisciplinary Studies of HIV/AIDS and Aging (R21)
Amount £205,531 (GBP)
Funding ID 1R21AG053093 - 01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2016 
End 04/2019
 
Description NIH MIDAS Initiative: Mathematical Models in the study of Infectious Disease spread and control (2009-14)
Amount £768,126 (GBP)
Funding ID 1U54GM088491-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 07/2009 
End 06/2014
 
Description NIH NIAD: New methods for the design and evaluation of large HIV prevention interventions
Amount £111,000 (GBP)
Funding ID 1R01AI112339-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 06/2014 
End 05/2018
 
Description NIH: Genetic epidemiology of malaria in the Democratic Republic of Congo
Amount £300,000 (GBP)
Funding ID 1R01AI107949-01A1 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 04/2015 
End 03/2016
 
Description NIH: Methodologies and Formative Work for Combination HIV Prevention Approaches
Amount £117,604 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 07/2014 
End 02/2017
 
Description NIH: PopART-Phylogenetics
Amount £83,044 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 06/2013 
End 11/2018
 
Description NIH: PopART: Cluster randomized trial of the impact of a combination HIV prevention
Amount £1,531,054 (GBP)
Funding ID HPTN 071 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 10/2011 
End 11/2018
 
Description NIH: Targeting Primary Infection with Antiretrovirals to Prevent Transmission
Amount £165,096 (GBP)
Funding ID 1R01 AI083059-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 08/2009 
End 07/2014
 
Description NIH: The immune landscape of human influenza in households, towns and cities in southern China
Amount £212,974 (GBP)
Funding ID 5R01TW008246-04 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 01/2011 
End 08/2015
 
Description NIHR - Senior Investigators Award (budget uplift)
Amount £45,000 (GBP)
Funding ID P/O 427921 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2014 
End 04/2018
 
Description NIHR HTA: The cost effectiveness of genetic markers for antibiotic resistance in tuberculosis.
Amount £48,496 (GBP)
Funding ID 10/96/01 
Organisation National Institute for Health Research 
Department Health Technology Assessment Programme (HTA)
Sector Public
Country United Kingdom
Start 10/2011 
End 12/2013
 
Description NIHR Senior Investigator Award
Amount £120,000 (GBP)
Funding ID P/O 427921 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2009 
End 03/2017
 
Description NIHR: HPRU in Respiratory Infections at Imperial College London
Amount £14,021 (GBP)
Funding ID WHRR_P47123 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2014 
End 03/2019
 
Description NIHR: Interferon gamma tests for the rapid identification of active tuberculosis disease
Amount £79,228 (GBP)
Funding ID 08/106/02 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 03/2011 
End 02/2015
 
Description NIHR: NIHR HPRU in Modelling Methodology
Amount £3,528,583 (GBP)
Funding ID HPRU-2012-10080 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2014 
End 03/2019
 
Description NIHR: TB Reach: Improving the management and control of tuberculosis among hard to reach groups
Amount £100,000 (GBP)
Funding ID RP-PG-0407-10340 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 09/2008 
End 08/2013
 
Description NIHR: Targeting men for better sexual health: The Ballseye Programme
Amount £73,171 (GBP)
Funding ID RP-PG-0707-10208 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 02/2009 
End 02/2014
 
Description NIHR: Validation of new technologies for diagnosis and treatment evaluation of tuberculosis
Amount £49,000 (GBP)
Funding ID 12/65/27 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 03/2014 
End 06/2018
 
Description Near-Infrared Spectroscopy: A One-Stop-Shop for Mosquito Epidemiological Monitoring (Tom Churcher)
Amount £643,883 (GBP)
Funding ID MR/P01111X/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2017 
End 02/2020
 
Description Optimal spatial scales for deployment of multiple first line therapies for malaria
Amount £105,750 (GBP)
Funding ID RGF\EA\180225 
Organisation Royal Society of Medicine 
Sector Learned Society
Country United Kingdom
Start 12/2017 
End 03/2021
 
Description PATH/MVI/Gates: Modelling the public health impact and cost-effectiveness of the RTS,S malaria vaccine in malaria endemic countries
Amount £302,135 (GBP)
Funding ID GAT.0888-07-06258-CRT 
Organisation Program for Appropriate Technology in Health (PATH) 
Sector Charity/Non Profit
Country United States
Start 06/2013 
End 12/2018
 
Description PATH/MVI: Measuring the population efficacy of TBIs - the Transmission Population Assay
Amount £1,010,322 (GBP)
Funding ID GAT.0888-11-06546-COL 
Organisation Program for Appropriate Technology in Health (PATH) 
Sector Charity/Non Profit
Country United States
Start 10/2013 
End 07/2016
 
Description Pathfinder: Experimental Human Challenge with Genetically Modified Commensals to Investigate Respiratory Tract Mucosal Immunity and Colonisation (Xavier Didelot)
Amount £18,598 (GBP)
Funding ID MR/N026993/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2017 
End 07/2020
 
Description Phase variable epigenetic regulation in Firmicutes (Nick Croucher)
Amount £298,700 (GBP)
Funding ID RM33G0360 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 01/2016 
End 12/2018
 
Description Population Effects of Antretroviral Therapy to Reduce HIV Transmission (PopART) - Health Economics
Amount £451,028 (GBP)
Funding ID PO15001410 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 06/2015 
End 05/2018
 
Description Population Effects of Antretroviral Therapy to Reduce HIV Transmission (PopART) - Health Economics
Amount £13,115 (GBP)
Organisation Government of the UK 
Department Department for International Development (DfID)
Sector Public
Country United Kingdom
Start 11/2015 
End 07/2018
 
Description Predicting the impact of insecticide resistance and new paradigms of vector control (Tom Churcher)
Amount £161,331 (GBP)
Organisation IVCC 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2015 
End 02/2018
 
Description Providing academic leadership through a Secretariat for the UNAIDS reference group on estimates modelling & projections
Amount £222,968 (GBP)
Funding ID EIP/DFA/PG/ca12/18 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS) 
Sector Public
Country Global
Start 01/2013 
End 12/2014
 
Description Providing academic leadership through a Secretariat for the UNAIDS reference group on estimates modelling & projections
Amount £634,543 (GBP)
Funding ID PO201153562 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS) 
Sector Public
Country Global
Start 01/2015 
End 12/2017
 
Description Providing academic leadership through a Secretariat for the UNAIDS reference group on estimates modelling & projections (2018-2019)
Amount £468,709 (GBP)
Funding ID 2017/778519 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS) 
Sector Public
Country Global
Start 01/2018 
End 12/2019
 
Description Quantifying and preparing for the non-communicable disease burden in the ageing HIV-positive population in Kenya
Amount £134,891 (GBP)
Funding ID OISE-17-62962-1 
Organisation United States President's Emergency Plan for AIDS Relief 
Sector Public
Country United States
Start 08/2017 
End 09/2018
 
Description Quantifying future clinical burden of an ageing HIV-positive patient population: a modelling analysis for the USA and Italy
Amount £110,000 (GBP)
Funding ID 212011616 
Organisation Gilead Sciences, Inc. 
Sector Private
Country United States
Start 05/2016 
End 12/2016
 
Description RO1 - Statistical Models for Estimating and Projecting HIV/AIDS Epidemics (Jeff Eaton)
Amount £11,080 (GBP)
Funding ID 5776-ICS-DHHS-6664 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2017 
End 08/2018
 
Description Research Project Grant (R01) PA-07-070
Amount $122,980 (USD)
Organisation National Institute of Allergy and Infectious Diseases (NIAID) 
Sector Public
Country United States
Start 09/2015 
End 02/2016
 
Description Research and Development of Reconstructing HIV Epidemics from HIV Phylogenetics
Amount £54,832 (GBP)
Funding ID 340798 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2015 
End 02/2018
 
Description RooPfs (Can improved housing provide additional protection against clinical malaria over current practice? A household-randomised controlled trial) (Lesong Conteh)
Amount £179,101 (GBP)
Funding ID MR/M007383/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 11/2014 
End 10/2018
 
Description Royal Society University Research Fellowship: Mathematical Modelling of Human Contact Networks and Implications for Infectious Disease
Amount £670,090 (GBP)
Funding ID 516002.K5789/KK UF041279 
Organisation Royal Society of Medicine 
Sector Learned Society
Country United Kingdom
Start 10/2004 
End 03/2013
 
Description Rush Foundation: Understanding Health Externalities in HIV Intervention To Inform Budget Allocation in Africa
Amount £444,000 (GBP)
Organisation Rush Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2013 
End 07/2016
 
Description Secretariat of the UNAIDS Reference Group on Estimates, Modelling, and Projections
Amount $559,766 (USD)
Funding ID SIE/SIM/PG/MM/ca/14/20 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS) 
Sector Public
Country Global
Start 01/2015 
End 12/2016
 
Description Sir Henry Dale Fellowship - Nick Croucher (Evolutionary dynamics underlying pneumococcal genomic diversity)
Amount £708,513 (GBP)
Funding ID 104169/Z/14/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2014 
End 09/2019
 
Description Sir Henry Wellcome Fellowship. Modelling the impact of HSV-2 interventions on HIV transmission in sub-Saharan Africa.
Amount £245,383 (GBP)
Funding ID WT082623 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2008 
End 02/2013
 
Description Spatial Uncertainty: Data, Modeling, and Communication (R03) (Jeff Eaton)
Amount £73,697 (GBP)
Funding ID 1R03AI125001-01A1 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 12/2016 
End 11/2018
 
Description Statistical model for SMFA precision (Tom Churcher)
Amount £76,406 (GBP)
Funding ID R0002102 MVI-SMFA 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 03/2014 
End 12/2015
 
Description Target Malaria - Controlling the mosquito vectors of malaria with engineered endonucleases
Amount £231,402 (GBP)
Funding ID OPP1141988 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 08/2016 
End 01/2020
 
Description The Cost-Effectiveness of Pre-Exposure Prophylaxis (PrEP) Treatment for HIV
Amount £177,479 (GBP)
Organisation Viiv Healthcare 
Sector Private
Country United Kingdom
Start 06/2015 
End 05/2016
 
Description The Interaction Between Hormonal Contraceptives and HIV Risk
Amount £719,972 (GBP)
Funding ID OPP1067133 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2012 
End 02/2017
 
Description The delay-care cascade and its implications for TB transmission: a study in three country settings (Nim Pathy)
Amount £70,160 (GBP)
Funding ID STBP/USAID/GSA/92954/2017-21 
Organisation United Nations Office for Project Services 
Sector Public
Country United States
Start 08/2017 
End 02/2018
 
Description The evolution of influenza virus; Studies of within host and between host evolution to improve pandemic risk assessment and vaccine updates
Amount £165,459 (GBP)
Funding ID 200187/Z/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2016 
End 03/2020
 
Description The life course of human immune responses to influenza infection and vaccination
Amount £1,882,747 (GBP)
Funding ID 200861/Z/16/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2016 
End 04/2021
 
Description UNAIDS: Providing academic leadership through a Secretariat for the UNAIDS reference group on estimates modelling & projections (extension)
Amount £222,968 (GBP)
Funding ID EIP/DFA/PG/ca12/18 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS) 
Sector Public
Country Global
Start 01/2013 
End 12/2014
 
Description Understanding Assays Used to Measure Malaria Transmission-Blocking Activity: Bridging Data Between the Laboratory and the Field
Amount £79,079 (GBP)
Funding ID IRD 304549/00 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 12/2013 
End 07/2016
 
Description Vaccine Impact Modelling Consortium (VIMC) - Secretariat
Amount £3,757,557 (GBP)
Funding ID OPP1157270 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 12/2016 
End 03/2022
 
Description Vaccine Impact Modelling Consortium (VIMC) - Sub-contracts
Amount £3,246,881 (GBP)
Funding ID PO008511 
Organisation Bill and Melinda Gates Foundation 
Department Global Alliance for Vaccination and Immunisation (GAVI)
Sector Charity/Non Profit
Country Switzerland
Start 01/2017 
End 03/2022
 
Description WHO Guidelines ARV Revision 2015
Amount £15,587 (GBP)
Funding ID 2015/523611-0 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 01/2015 
End 09/2016
 
Description WHO: Developing a model of the impact of artemisinin resistance
Amount £27,990 (GBP)
Funding ID PO 200833521 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 01/2013 
End 12/2013
 
Description WHO: Economic appraisals of seasonal influenza vaccine in low & middle income countries (LMIC) - Work Package 3
Amount £7,000 (GBP)
Funding ID EPIDZC14 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 10/2013 
End 08/2014
 
Description WHO: Gut mucosal immunity induced by vaccine and wild-type poliovirus in India
Amount £99,091 (GBP)
Funding ID PO 200245063 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 08/2010 
End 08/2013
 
Description WHO: HIV Modelling Consortium WHO Guidelines - 2013
Amount £62,836 (GBP)
Funding ID HIV/SIP 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 10/2012 
End 01/2013
 
Description WHO: Statistical and mathematical analysis of polio surveillance data to support the endgame
Amount £218,091 (GBP)
Funding ID 200953530 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 03/2014 
End 12/2016
 
Description Wellcome Trust Collaborative Award
Amount £165,459 (GBP)
Funding ID 200187/Z/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2016 
End 01/2020
 
Description Wellcome Trust Fellowship - Epidemiology and evolution of pathogenic human enteroviruses - Margarita Pons Salort
Amount £250,000 (GBP)
Funding ID 106073/Z/14/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2015 
End 02/2019
 
Description Wellcome Trust Fellowship: Merging theory and field studies for infectious disease dynamics
Amount £581,029 (GBP)
Funding ID 093488/Z/10/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2011 
End 05/2016
 
Description Wellcome Trust Fellowship: The effect of population structure on the evolution and progression of infectious disease
Amount £264,829 (GBP)
Funding ID 091737/Z/10/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2011 
End 01/2016
 
Description Wellcome Trust Fellowship: Uncovering Determinants of eco-evo Pathogen Dynamics with ABCì.
Amount £250,000 (GBP)
Funding ID 092311/Z/10/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2010 
End 09/2014
 
Description Wellcome Trust Four-Year PhD Studentship - Miss Isobel Routledge
Amount £165,784 (GBP)
Funding ID 109310/Z/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2015 
End 09/2019
 
Description Wellcome Trust Four-Year PhD Studentship - Mr Finlay Campbell
Amount £165,784 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2015 
End 09/2019
 
Description Wellcome Trust Four-Year PhD Studentship - Mr Oliver J Watson
Amount £165,784 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2015 
End 09/2019
 
Description Wellcome Trust Four-Year PhD Studentship - Mr Robin Maximillian Schaefer
Amount £165,784 (GBP)
Funding ID 109313/Z/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2015 
End 09/2019
 
Description Wellcome Trust PhD Programme for Clinicians Fellowship for Bhargavi Rao: Artemisinin combination therapy and the health system
Amount £245,728 (GBP)
Funding ID 090791/Z/09/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2010 
End 08/2013
 
Description Wellcome Trust: Studentship for Marcus Shepheard
Amount £145,130 (GBP)
Funding ID 083705/Z/07/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2007 
End 07/2014
 
Description World Bank: Investigating reasons for epidemiological changes in HIV in African countries
Amount £462,124 (GBP)
Funding ID 7164102 
Organisation World Bank Group 
Sector Private
Country United States
Start 08/2012 
End 06/2016
 
Description Yellow Fever - Impact of immunisation in Africa
Amount £117,089 (GBP)
Funding ID OPP1117543 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2014 
End 12/2016
 
Description Zika in Columbia: early characterisation of epidemiological potential
Amount £149,824 (GBP)
Funding ID MC_PC_15091 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2016 
End 09/2017
 
Description Zika: A fast new intervention and an innovative method of evaluation (Tom Churcher)
Amount £34,518 (GBP)
Funding ID WPIA_P66851 
Organisation QIMR Berghofer Medical Research Institute 
Sector Multiple
Country Australia
Start 10/2016 
End 12/2019
 
Title Platform RECON Learn 
Description Website for online training (RECON Learn) 
Type Of Material Improvements to research infrastructure 
Year Produced 2017 
Provided To Others? Yes  
Impact Used in training 
URL https://reconlearn.netlify.com/
 
Title Climate data dataset 
Description Global climate data , different geographic resolutions to be used to inform models of dengue and other vector-borne diseases 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact Feeding into the dengue model, used to produce global risk maps of dengue infection 
 
Title Colombia - Chagas Costs (Colombia Chagas individual level provider treatment costs) 
Description The dataset comprises information of medical visits and costs of 7164 individuals with diagnosis of Chagas disease in Colombia between 2010-2014. The data was obtained from the Individual Registers for Health Services in Colombia at the Ministry of Health and integrated with four different dictionaries and algorithms to classify the stages of the disease and trajectories of care for this population. 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact No impact yet. Will be part of a publication and costs & CE eventually reported back to Colombian MoH. 
 
Title Colombia - Chagas Costs- Colombia Chagas individual level provider treatment costs 
Description The dataset comprises information of medical visits and costs of 7164 individuals with diagnosis of Chagas disease in Colombia between 2010-2014. The data was obtained from the Individual Registers for Health Services in Colombia at the Ministry of Health and integrated with four different dictionaries and algorithms to classify the stages of the disease and trajectories of care for this population. 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? No  
Impact No impact yet (Will be part of a publication and costs & CE eventually reported back to Colombian MoH) 
 
Title Database from a systematic review on different diagnostics on malaria - 2015 
Description Comparison of diagnostics for the detection of asymptomatic Plasmodium falciparum infections to inform control and elimination strategies. 
Type Of Material Database/Collection of data 
Year Produced 2015 
Provided To Others? Yes  
Impact PMID: 26633770 
 
Title Dataset from the EVI study 
Description Dataset on the correlates of immunogenicity for oral poliovaccines 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact Ability to predict vaccine response and effectiveness 
 
Title Discriminant Analysis of Principal Components (DAPC) 
Description a multivariate method designed to identify and describe clusters of genetically related individuals. When group priors are lacking, DAPC uses sequential K-means and model selection to infer genetic clusters. Our approach allows extracting rich information from genetic data, providing assignment of individuals to groups, a visual assessment of between-population differentiation, and contribution of individual alleles to population structuring. 
Type Of Material Data handling & control 
Year Produced 2010 
Provided To Others? Yes  
Impact most highly accessed paper in BMC Genetics since its publication 6 weeks ago 
 
Title Ebola data analysis tools -2015 
Description Wide range of statistical and modelling methods for the analysis of Ebola and other infectious disease outbreaks 
Type Of Material Data analysis technique 
Year Produced 2015 
Provided To Others? Yes  
Impact PMID: 25539446, 26029377 
 
Title Estimating local chlamydia incidence and prevalence using surveillance data 
Description Synthesizes local surveillance data on rates of chlamydia testing and diagnosis with information on natural history 
Type Of Material Data analysis technique 
Year Produced 2016 
Provided To Others? Yes  
Impact Corresponding publication in press 
 
Title Estimating the reproduction number in real time CF 
Description Estimating the reproduction number in real time. Excel package and R package. Computer packages that will allow non-specialist to better analyse outbreaks 
Type Of Material Data analysis technique 
Provided To Others? No  
Impact Ready to be released, will be released with paper which is under review. Has been piloted during our 2 week short course, was very enthusiastically received 
 
Title Estimation of clearance rate of chlamydia 
Description synthesises data on rates of chlamydia clearance with different time-points to infer rates of clearance with greater precision 
Type Of Material Data analysis technique 
Year Produced 2017 
Provided To Others? Yes  
Impact Corresponding publication in press 
URL https://github.com/joanna-lewis/ct_clearance
 
Title Exploration of the power of routine surveillance data to assess the impacts of industry-led badger culling on bovine tuberculosis incidence in cattle herds - 2015 
Description How to assess the statistical power of testing for effects of badger culling 
Type Of Material Data analysis technique 
Year Produced 2015 
Provided To Others? Yes  
Impact PMID: 26374782 
 
Title FluScape Project data set - 2015 
Description The Fluscape cohort is a longitudinal cohort that looks at influenza infection in a detailed manner and pairs this with information on social contacts. By working on a fine geographical scale in a randomly selected communities with characterized contact patterns and immune profile, the Fluscape cohort attempts to relate the infection risk of individuals to their social contact patterns and to the connectivity of the community in which they live.  
Type Of Material Database/Collection of data 
Year Produced 2015 
Provided To Others? Yes  
Impact Several publications and ongoing work 
 
Title Forecasting incidence 
Description Null model to predict future incidence 
Type Of Material Data analysis technique 
Year Produced 2017 
Provided To Others? Yes  
Impact Ability to produce better forecast data 
 
Title From malaria control to malaria elimination: a manual for elimination scenario planning - 2014 
Description Computer software to evaluate the potential impact of malaria interventions in African countries 
Type Of Material Computer model/algorithm 
Year Produced 2014 
Provided To Others? Yes  
Impact The tool has been formally released as part of a WHO guidance document. It was applied in Rwanda in September 2014 as part of their assessment of the feasibility of malaria elimination 
URL http://www.who.int/malaria/publications/atoz/9789241507028/en/
 
Title Geograph R package 
Description Geograph is a framework for GIS analyses in R. A typical application would be computing friction routes. It is more flexible than any currently available GIS freeware and has some unique features, such as the ability to work on a spherical referential rather than 2D maps; this is important when working at large geographic scales as any 2D projection of the world (or large regions thereof) will lead to considerable deformation. 
Type Of Material Data analysis technique 
Year Produced 2009 
Provided To Others? Yes  
Impact used for analysis of geographical data in 19586946 
 
Title Global Dengue Transmission Map 
Description This publicly available web tool visualises by adm1 region estimates of dengue force of infection derived from age-stratified seroprevalence and incidence estimates. The webtool also calculates expected seroprevalence at each age, and the age at which a target seroprevalence is reached. 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact This web tool was commissioned by and approved by the World Health Organization IVIR-AC committee and forms part of the official package of "tools to support decision-making for the addition of the licensed dengue vaccine into a public immunization programme" (http://www.who.int/immunization/research/development/dengue_serosurveys/en/) 
URL https://mrcdata.dide.ic.ac.uk/_dengue/dengue.php
 
Title HBV model - 2016 
Description A model that helps to evaluate HBV vaccination policy 
Type Of Material Computer model/algorithm 
Year Produced 2016 
Provided To Others? Yes  
Impact A model that helps to evaluate impact of the current vaccination policy and to evaluate policy choices going forward for China CDC 
 
Title Hong Kong Flu Contacts - 2014 
Description Contact and serological data form Hong Kong 
Type Of Material Database/Collection of data 
Year Produced 2014 
Provided To Others? Yes  
Impact Too early to determine. 
URL http://rspb.royalsocietypublishing.org/content/281/1789/20140709/suppl/DC1
 
Title Imperial College/Public Health Foundation of India (ICPHFI) model for the TB epidemic in India - 2014 
Description Model developed to capture the healthcare system in India, and TB transmission 
Type Of Material Computer model/algorithm 
Year Produced 2014 
Provided To Others? Yes  
Impact Model is being applied to address different questions of TB strategy, by PHFI colleagues 
 
Title Large scale kernels 
Description general method for fitting spatial processes with complete flexibility 
Type Of Material Computer model/algorithm 
Year Produced 2016 
Provided To Others? Yes  
Impact 1 paper under revision 
 
Title Malaria - Housing Preference Dataset 
Description Xls / Stata, preferences of n=400 households who are recipients of the Roopfs housing intervention. Data base was generated through a cross-section survey among households receiving house improvements as part of a Randomized-controlled trial in The Gambia. They were asked about money spent on housing, about their satisfaction with the house (and its components) and about malaria perception, in addition to personal/socio-economic characteristics. 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact Analysis and publications in progress 
 
Title Malaria - Housing Preference Dataset. Roopfs Study - Housing Preferences in Rural Gambia 
Description Xls / Stata, preferences of n=400 households who are recipients of the Roopfs housing intervention. Data base was generated through a cross-section survey among households receiving house improvements as part of a Randomized-controlled trial in The Gambia. They were asked about money spent on housing, about their satisfaction with the house (and its components) and about malaria perception, in addition to personal/socio-economic characteristics. 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? No  
Impact Analysis and publications in progress 
 
Title Malaria - SMC risk perception 
Description Xls / Stata, preferences of n=2000 respondents who are recipients of the Roopfs housing intervention. Data base was generated through a cross-section survey among households receiving SMC Randomized-controlled trial in Burkina Faso. 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact Analysis and publications in progress. 
 
Title Malaria - SMC risk perception SMC perceived malaria risk, migration& remittances - Burkina Faso & Mali 
Description Xls / Stata, preferences of n=2000 respondents who are recipients of the Roopfs housing intervention. Data base was generated through a cross-section survey among households receiving SMC Randomized-controlled trial in Burkina Faso. 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? No  
Impact Analysis and publications in progress 
 
Title Malaria drug resistance mutations database 
Description Systematic review of sulphadoxine-pyrimethamine resistance in plasmodium falciparum 
Type Of Material Database/Collection of data 
Year Produced 2016 
Provided To Others? Yes  
Impact None yet. 
 
Title Meta analysis of impact of pyrethoid resistance on mosquito control 
Description Generated and analysed a database and provided raw data and analysis online 
Type Of Material Computer model/algorithm 
Year Produced 2016 
Provided To Others? Yes  
Impact Provided online meta analysis of the impact of pyrethoid resistance on mosquito control 
URL https://elifesciences.org/content/5/e16090
 
Title Methods of determining Malaria elimination - 2014 
Description method to determine whether malaria will be eliminated from a country if disease importation ceased 
Type Of Material Data analysis technique 
Year Produced 2014 
Provided To Others? Yes  
Impact method is being discussed by WHO 
URL http://www3.imperial.ac.uk/newsandeventspggrp/imperialcollege/newssummary/news_12-6-2014-18-17-49
 
Title Model Library for TB models -2017 
Description Library of curated TB models for use by students and collaborators 
Type Of Material Computer model/algorithm 
Year Produced 2017 
Provided To Others? Yes  
Impact Used library to teach TB modelling to collaborators 
 
Title Model for estimating mutation frequencies in parasites 
Description R-code for estimating mutation frequencies from data on the prevalence of drug resistance in infected humans 
Type Of Material Computer model/algorithm 
Year Produced 2016 
Provided To Others? Yes  
Impact None yet 
 
Title Montagu 
Description Vaccine impact estimates generated by the members of the VIMC specifying estimated disease burden for ten diseases in 98 low and middle income countries 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? No  
Impact Informing the funders regarding the impact of vaccination they fund 
URL https://montagu.vaccineimpact.org/
 
Title Outbreaks 
Description open data on outbreaks 
Type Of Material Database/Collection of data 
Year Produced 2016 
Provided To Others? Yes  
Impact over 500 downloads per month from predominantly external users 
URL http://www.repidemicsconsortium.org/outbreaks
 
Title PCR data sets analysis improvement - 2015 
Description PCR (polymerase chain reaction) data analysis technique normally does not have uncertainty around it, the new analysis technique generates 95% confidence intervals for quantitative PCR derived data. 
Type Of Material Data analysis technique 
Year Produced 2015 
Provided To Others? Yes  
Impact Paper published: "Improving statistical inference on pathogen densities estimated by quantitative molecular methods: malaria gametocytaemia as a case study" 
 
Title Patterns of TB care seeking in urban slums in India (The Foundation for Medical Research, India) - 2015 
Description Arising from surveys in urban slums in India (in Patna and Mumbai), the database casts fresh light on the care seeking amongst TB patients in these areas. The surveys were conducted by the Foundation for Medical Research, and Dr. Pathy's involvement is to help them in its statistical analysis. 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact Performing statistical analysis for a paper to be published 
 
Title Providing quality of life estimates for people who live in Sub -Saharan Africa 
Description Parameter estimates for future studies 
Type Of Material Data analysis technique 
Year Produced 2017 
Provided To Others? Yes  
Impact Not yet 
 
Title Public Health England Serum Archive data - 2015 
Description It is a database of anitbody titres for different influenza strains for anonymized samples collected in england and wales between 1999 and 2004 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact Not published yet. 
 
Title Rakai dataset - 2016 
Description Dataset with epidemiological information on HIV incident cases and HIV serodiscordent couples in the Rakai communities in Uganda 
Type Of Material Database/Collection of data 
Year Produced 2016 
Provided To Others? Yes  
Impact Publically available 
URL http://datadryad.org/resource/doi:10.5061/dryad.7kr85
 
Title SP resistance 
Description Systematic review of the prevalence of mutations associated with resistance to the antimalarial drug sulphadoxine-pyrimethamine. 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact Shared with WHO and the Worldwide Antimalarial Resistance Network. 
URL https://www.ncbi.nlm.nih.gov/pubmed/28785011
 
Title SeqTrack 
Description SeqTrack is an algorithm for reconstructing genealogies implemented in the adegenet package in the R environment 
Type Of Material Computer model/algorithm 
Year Produced 2010 
Provided To Others? Yes  
Impact none as yet 
 
Title Stacking 
Description ensemble method to combine metamodels 
Type Of Material Computer model/algorithm 
Year Produced 2016 
Provided To Others? Yes  
Impact 2 pubs in Nature (IHME) and 1 pub in Royal Society Interface (IC) 
 
Title TB Burden inference through drug sales method 
Description TB Burden inference through drug sales method 
Type Of Material Computer model/algorithm 
Year Produced 2016 
Provided To Others? Yes  
Impact IMS health using in collab with Gates foundation 
URL http://www.sciencedirect.com/science/article/pii/S1473309916302596
 
Title The role of rapid diagnostics in managing Ebola epidemics - 2015 
Description Evaluating for optimal strategy in use of different forms of diagbostic tools 
Type Of Material Data analysis technique 
Year Produced 2015 
Provided To Others? Yes  
Impact Publically available analysis tools for download in Excel - PMID: 26633764 
 
Title TransPhylo (2014) 
Description Software package for the Bayesian inference of infectious disease transmission from a phylogeny. The input is a dated phylogeny, where leaves correspond to pathogens isolated from the infected hosts. The main output is a transmission tree which indicates who infected whom. Such reconstruction can be achieved by colouring the branches of the phylogeny using a separate colour for each host, and such that the subtree coloured in a given colour represents the evolution happening within the corresponding host. Changes of colours on branches therefore correspond to transmission events from one host to another. 
Type Of Material Computer model/algorithm 
Year Produced 2014 
Provided To Others? Yes  
Impact PMID 24714079 
URL https://code.google.com/p/transphylo/
 
Title UK HIV Drug Resistance Sequences Database - 2015 
Description Analysis of clinical and demographic patient data through 2012 
Type Of Material Database/Collection of data 
Provided To Others? No  
Impact The HIV Drug Resistance Database provides a unique resource for molecular epidemiological studies of HIV transmission among more than 60 thousand patients diagnosed with HIV in the UK. The database contains unique information about risk factors for HIV transmission, and our group is developing and applying novel statistical approaches to mining this information with the ultimate goal of tailoring public health interventions to reduce transmission risk. 
URL http://www.hivrdb.org.uk/
 
Title Within-host model 
Description A within host model describing malaria parasites over time in patients, and the effects of drugs on them. 
Type Of Material Computer model/algorithm 
Year Produced 2017 
Provided To Others? Yes  
Impact None yet 
URL https://www.ncbi.nlm.nih.gov/pubmed/29123086
 
Title World Development Indicators - 2015 
Description In order to identify which determinants are most strongly associated with life expectancy, using extreme bound analysis technique applied to this publically available data set. 
Type Of Material Data analysis technique 
Provided To Others? No  
Impact Used for a forthcoming paper 
URL http://data.worldbank.org/data-catalog/world-development-indicators
 
Title colgem - 2013 
Description Software tool. 'Coalescent Liklihood for Generalized Epidemic Models'. This tool fits infectious disease models to pathogen genetic sequence data 
Type Of Material Data analysis technique 
Provided To Others? No  
Impact too early to know about this yet. 
URL https://code.google.com/p/colgem/
 
Title rcolgem - 2013 
Description Software tool. This tool fits infectious disease models to pathogen genetic sequence data 
Type Of Material Data analysis technique 
Year Produced 2014 
Provided To Others? Yes  
Impact currently being used by a researcher at Cambridge (vet. med) and Los Alamos Natl Laboratories. 
URL http://colgem.r-forge.r-project.org/
 
Title rcolgem - 2015 
Description rcolgem statistical inference and modeling of genealogies generated by epidemic and ecological processes. It is a package for phylodynamic inference using population genetic models. rcolgem implements coalescent models for populations with nonlinear dynamics and potentially many demes. 
Type Of Material Data analysis technique 
Year Produced 2015 
Provided To Others? Yes  
Impact Used in various publications. For ex. http://www.ncbi.nlm.nih.gov/pubmed/26006189 
URL http://colgem.r-forge.r-project.org
 
Description Achtman XD 2012 
Organisation University College Cork
Department Environmental Research Institute
Country Ireland 
Sector Academic/University 
PI Contribution Statistical analysis of genetic data from Salmonella enterica, Helicobacter pylori, Yersinia pseudotuberculosis, Vibrio cholerae.
Collaborator Contribution Sampling of bacterial isolates, multi-locus sequence typing and whole-genome sequencing.
Impact PMID 21951486, 21829375, 20935094, 20661309, 22737074.
Start Year 2010
 
Description An integrated approach to understand the emergence and spread of extensively resistant Gram-negative bacteria in China (UCL, Cambridge) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Statistical analysis of genomic data from E. coli and K. pneumoniae, especially isolates resistant to carbapenem
Collaborator Contribution Sampling of isolates, whole-genome sequencing, in vitro experiments.
Impact doi: https://doi.org/10.1101/220921
Start Year 2017
 
Description An integrated approach to understand the emergence and spread of extensively resistant Gram-negative bacteria in China (UCL, Cambridge) 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution Statistical analysis of genomic data from E. coli and K. pneumoniae, especially isolates resistant to carbapenem
Collaborator Contribution Sampling of isolates, whole-genome sequencing, in vitro experiments.
Impact doi: https://doi.org/10.1101/220921
Start Year 2017
 
Description Analysis of early H1N1 outbreak in UK 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution Collaborative analysis of early H1N1 case data from the UK
Collaborator Contribution Provision of early data on H1N1 pandemic in the UK
Impact The Early Transmission Dynamics of H1N1pdm Influenza in the United Kingdom Azra C Ghani1*, Marc Baguelin2*, Jamie T Griffin1*, Stefan Flasche2,6*, Richard Pebody2*, Albert Jan Van Hoek2*, Simon Cauchemez1, Ian M Hall 3, Christl A Donnelly1, Chris Robertson4,6, Michael T White1, Iain Barrass3, Christophe Fraser1, Alison Bermingham2, James Truscott1, Joanna Ellis2, Helen E Jenkins1, George Kafatos2, Tini Garske1, Ross Harris2, Jim McMenamin4, Colin Hawkins2, Nick Phin2, André Charlett2, Maria Zambon2, W. John Edmunds2,5, Mike Catchpole2, Steve Leach3, Peter J White1,2, Neil M Ferguson1+, Ben S. Cooper2+. In Review and also available on PLoS Currents - Influenza
Start Year 2009
 
Description Analysis of the 2009-10 influenza pandemic PW 
Organisation Department of Health (DH)
Country United Kingdom 
Sector Public 
PI Contribution Contribution to study design and analysis
Collaborator Contribution Study design and analysis
Impact Campbell et al. Epidemiology and Infection 2011;139(10):1560-1569 Clinical medicine Epidemiology Public health Statistics
Start Year 2009
 
Description Analysis of the 2009-10 influenza pandemic PW 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution Contribution to study design and analysis
Collaborator Contribution Study design and analysis
Impact Campbell et al. Epidemiology and Infection 2011;139(10):1560-1569 Clinical medicine Epidemiology Public health Statistics
Start Year 2009
 
Description Armand Sprecher and Dirk Schumacher 
Organisation Médecins Sans Frontières (MSF)
Country France 
Sector Charity/Non Profit 
PI Contribution Developing model and r package for optimising contact tracing efforts
Collaborator Contribution Formulating needs for contact tracing efforts during emergency outbreak response
Impact r package Tracer has been published
Start Year 2016
 
Description BEEHIVE - Academic Medical Centre -2013 
Organisation HIV Monitoring Foundation (SHM)
Country Netherlands 
Sector Charity/Non Profit 
PI Contribution BEEHIVE (Bridging the Evolution and Epidemiology of HIV in Europe). Pilot feasibility study
Collaborator Contribution AMC collected samples from Dutch hospitals, storing and documenting them prior to sending to Sanger
Impact European Research Council have awarded a GBP £2m 'Advance Grant' to Imperial College for further research arising out of the pilot study.
Start Year 2010
 
Description BEEHIVE - Wellcome Trust -2013 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution BEEHIVE (Bridging the Evolution and Epidemiology of HIV in Europe). Pilot feasibility study
Collaborator Contribution Sanger carried out genetic sequencing of samples and supplied the research data to Imperial and AMC.
Impact European Research Council have awarded a GBP £2m 'Advance Grant' to Imperial College for further research arising out of the pilot study.
Start Year 2010
 
Description BEEHIVE: Bridging the Evolution and Epidemiology of HIV in Europe (2014) 
Organisation Academic Medical Center
Country Netherlands 
Sector Academic/University 
PI Contribution Leadership & scientific coordination
Collaborator Contribution Scientific collaboration; providing data, samples & laboratory analysis/work.
Impact More cohorts involved than anticipated, but too early to report scientific impacts.
Start Year 2011
 
Description BEEHIVE: Bridging the Evolution and Epidemiology of HIV in Europe (2014) 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Leadership & scientific coordination
Collaborator Contribution Scientific collaboration; providing data, samples & laboratory analysis/work.
Impact More cohorts involved than anticipated, but too early to report scientific impacts.
Start Year 2011
 
Description Baylor College of Medicine 
Organisation Baylor College of Medicine
Country United States 
Sector Hospitals 
PI Contribution Lead coordinator on a study and design of clinical study design
Collaborator Contribution Rotavirus virology; mass spectrometry for breast milk study
Impact N/A
Start Year 2016
 
Description Baylor College of Medicine 
Organisation University of California, San Francisco
Country United States 
Sector Academic/University 
PI Contribution Lead coordinator on a study and design of clinical study design
Collaborator Contribution Rotavirus virology; mass spectrometry for breast milk study
Impact N/A
Start Year 2016
 
Description Biomedical Research and Training Institute (BRTI) 
Organisation Biomedical Research and Training Institute (BRTI)
Country Zimbabwe 
Sector Charity/Non Profit 
PI Contribution Analysis
Collaborator Contribution Field work
Impact Grant
Start Year 2017
 
Description Blue-Tongue Virus Modelling for UK 
Organisation Department For Environment, Food And Rural Affairs (DEFRA)
Country United Kingdom 
Sector Public 
PI Contribution Provided support in model coding and development
Impact Increased understanding of the dynamics and spread of Blue-Tongue virus in the UK.
Start Year 2009
 
Description CDC - ABC (Active Bacterial Core surveillance) - Captain Matt Moore - 2015 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution Data analysis and modelling
Collaborator Contribution Data interpretation and epidemiological analysis
Impact Forthcoming publication
Start Year 2015
 
Description CDC - Risk of air-travel spread of Yellow Fever Virus from Brazil into the United States 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution Dr Ilaria Dorigatti conducted the analysis (i.e. developed the methodological framework and implemented the code used to generate the results), wrote the reports and communicated the results to the CDC. Prof Christl Donnelly and Dr Tini Garske provided feedback on the analysis and results and participated to the discussion with the CDC about the implications of the results.
Collaborator Contribution The CDC provided the data necessary to conduct this research and useful discussion around the findings, which are currently being drafted in a publication on sustainable public health strategies involving vaccination that could avoid the introduction of Yellow Fever into the United States in future outbreaks.
Impact This analysis has informed the CDC on potential strategies to adopt in the future to prevent Yellow Fever introduction into the US. A paper will be submitted for publication.
Start Year 2017
 
Description CDC NG 2012 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution Analysis of genetic sequence data for poliovirus
Collaborator Contribution Provision of sequence data and joint analysis
Impact none yet
Start Year 2012
 
Description CHAI - Taryn Barker 
Organisation Clinton Health Access Initiative
Country United States 
Sector Charity/Non Profit 
PI Contribution Data analysis, guidance for programme operation
Collaborator Contribution Provide data
Impact 1 Manuscript under review - Journal TBC
Start Year 2016
 
Description CMC NG 2012 
Organisation Christian Medical College, Vellore
Department Wellcome Laboratory
Country India 
Sector Academic/University 
PI Contribution PI on a clinical trial of oral vaccines and collaborator on another
Collaborator Contribution Two clinical trials begun at CMC in Vellore, India
Impact too early
Start Year 2010
 
Description COSI 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC)
Country United Kingdom 
Sector Public 
PI Contribution statistical analysis of swine influenza
Collaborator Contribution access to data on swine influenza
Impact project funded by the BBSRC, MRC, Wellcome Trust (who contributed equally to the costs). DEFRA have also provided support
Start Year 2009
 
Description China CDC 
Organisation China Centre for Disease Control
Country China 
Sector Public 
PI Contribution Statistical description of the H1N1 pandemic in China
Collaborator Contribution We were provided access to data on the H1N1 pandemic in China and were able to gain an understanding of disease spread in this area of the world.
Impact Publication submitted to The Lancet
Start Year 2009
 
Description China CDC and China WHO 
Organisation Chinese Center for Disease Control and Prevention (China CDC)
Country China 
Sector Public 
PI Contribution Modelling expertise
Collaborator Contribution Provide data
Impact 1 Manuscript under review - Journal TBC
Start Year 2016
 
Description China Flu Studies-2013 
Organisation John Hopkins Centre for Global Health
Country United States 
Sector Charity/Non Profit 
PI Contribution Analysis of JHU-collected China data.
Collaborator Contribution Data has been collected by Justin Lessler (of JHU) in China.
Impact not yet
Start Year 2013
 
Description Clinical and cost-effectiveness of technologies for testing and treating sexual partners of people with sexually transmitted infections: Evidence synthesis and mathematical modelling study PW 2012 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Advice on transmission-dynamic modelling
Collaborator Contribution Systematic review Transmission-dynamic modelling
Impact Report for NIHR Paper submitted Statistics Public health Clinical medicine Health economics
Start Year 2009
 
Description Clinical and cost-effectiveness of technologies for testing and treating sexual partners of people with sexually transmitted infections: Evidence synthesis and mathematical modelling study PW 2012 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution Advice on transmission-dynamic modelling
Collaborator Contribution Systematic review Transmission-dynamic modelling
Impact Report for NIHR Paper submitted Statistics Public health Clinical medicine Health economics
Start Year 2009
 
Description Clinical and cost-effectiveness of technologies for testing and treating sexual partners of people with sexually transmitted infections: Evidence synthesis and mathematical modelling study PW 2012 
Organisation University of Bern
Country Switzerland 
Sector Academic/University 
PI Contribution Advice on transmission-dynamic modelling
Collaborator Contribution Systematic review Transmission-dynamic modelling
Impact Report for NIHR Paper submitted Statistics Public health Clinical medicine Health economics
Start Year 2009
 
Description Clinical and cost-effectiveness of technologies for testing and treating sexual partners of people with sexually transmitted infections: Evidence synthesis and mathematical modelling study PW 2012 
Organisation University of Birmingham
Country United Kingdom 
Sector Academic/University 
PI Contribution Advice on transmission-dynamic modelling
Collaborator Contribution Systematic review Transmission-dynamic modelling
Impact Report for NIHR Paper submitted Statistics Public health Clinical medicine Health economics
Start Year 2009
 
Description Clinical and cost-effectiveness of technologies for testing and treating sexual partners of people with sexually transmitted infections: Evidence synthesis and mathematical modelling study PW 2012 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Advice on transmission-dynamic modelling
Collaborator Contribution Systematic review Transmission-dynamic modelling
Impact Report for NIHR Paper submitted Statistics Public health Clinical medicine Health economics
Start Year 2009
 
Description Clinical and cost-effectiveness of technologies for testing and treating sexual partners of people with sexually transmitted infections: Evidence synthesis and mathematical modelling study PW 2012 
Organisation University of Sussex
Department Brighton and Sussex Medical School
Country United Kingdom 
Sector Academic/University 
PI Contribution Advice on transmission-dynamic modelling
Collaborator Contribution Systematic review Transmission-dynamic modelling
Impact Report for NIHR Paper submitted Statistics Public health Clinical medicine Health economics
Start Year 2009
 
Description Collaborating Institute on Polio-2013 
Organisation World Health Organization (WHO)
Country Global 
Sector Public 
PI Contribution Data analysis and modelling
Collaborator Contribution Polio data
Impact An indirect consequence of this collaboration is that funding from the WHO has successfully been sought, after WHO based individuals at the Collaborating Institute on Polio suggested that we should apply for funding. Our subsequent application was successful (see 'Global Polio Eradication Initiative' under further funding).
Start Year 2013
 
Description Collaboration re HIV and Hormonal Contraception TH 
Organisation University of Washington
Department International Clinical Research Centre (ICRC)
Country United States 
Sector Academic/University 
PI Contribution We analysed the data that this group has collected in new ways that have informed decision-making on several issues in relation to family planning needs.
Collaborator Contribution They write the proposed trial protocol and contribute clinical evidence.
Impact Paper: Butler et al
Start Year 2011
 
Description Collaboration with Univ of Pittsburgh (Don Burke) via NIH MIDAS network 
Organisation University of Pittsburgh
Country United States 
Sector Academic/University 
PI Contribution I developed pandemic influenza simulations for modelling intervention strategies
Collaborator Contribution Collection of data, exchange of ideas, interaction with US policymakers
Impact This work represented a major source of evidence to support pandemic preparedness work undertaken by the US, UK, WHO and other countries. Outputs were PubMed ID 16642006 and the following 2005 paper: Ferguson NM; Cummings DA; Cauchemez S; Fraser C; Riley S; Meeyai A; Iamsirithaworn S; Burke DS. (08 Sep 2005). Strategies for containing an emerging influenza pandemic in Southeast Asia. Nature. 437:209-214. (PubMed ID 16079797)
Start Year 2006
 
Description Combined Phylogenetic and Epidemiological Analysis in Seattle 
Organisation National Institutes of Health (NIH)
Country United States 
Sector Public 
PI Contribution Nothing yet
Collaborator Contribution Data collection in future
Impact Nothing yet.
Start Year 2014
 
Description Comparing Influenza transmission (between 1918 and 2009) - 2013 
Organisation Johns Hopkins University
Country United States 
Sector Academic/University 
PI Contribution analysis
Collaborator Contribution data provision and analysis
Impact not yet
Start Year 2013
 
Description Dengue Modelling Consortium JHU-2013 
Organisation Johns Hopkins University
Department Johns Hopkins Bloomberg School of Public Health
Country United States 
Sector Academic/University 
PI Contribution Founder. Also one of three academic groups providing modelling and analysis of Sanofi Pasteur's dengue vaccine candidate.
Collaborator Contribution Modelling and analysis of Sanofi Pasteur's dengue vaccine candidate.
Impact none yet
Start Year 2013
 
Description Dengue Modelling Consortium SP-2013 
Organisation Sanofi Pasteur MSD
Country United Kingdom 
Sector Private 
PI Contribution Founder. Modelling and analysis of Sanofi Pasteur's dengue vaccine candidate.
Collaborator Contribution Modelling and analysis of Sanofi Pasteur's dengue vaccine candidate.
Impact none yet
Start Year 2013
 
Description Dengue Modelling Consortium UoF-2013 
Organisation University of Florida
Country United States 
Sector Academic/University 
PI Contribution Founder. Modelling and analysis of Sanofi Pasteur's dengue vaccine candidate.
Collaborator Contribution Modelling and analysis of Sanofi Pasteur's dengue vaccine candidate.
Impact none yet
Start Year 2013
 
Description Dengue Modelling Consortium UoW-2013 
Organisation University of Washington
Department Department of Biostatistics
Country United States 
Sector Academic/University 
PI Contribution Founder. Modelling and analysis of Sanofi Pasteur's dengue vaccine candidate.
Collaborator Contribution Modelling and analysis of Sanofi Pasteur's dengue vaccine candidate.
Impact none yet
Start Year 2013
 
Description Dengue in Vietnam - 2012 
Organisation University of Oxford
Department Oxford University Clinical Research Unit Vietnam (OUCRU)
Country Viet Nam 
Sector Academic/University 
PI Contribution Expertise in mathematical modelling and statistical analysis of infectious disease data.
Collaborator Contribution Access to data on dengue infection in Vietnam
Impact Exchange and collection of data on dengue pathogenesis, impact of control measures and associated modelling.
Start Year 2009
 
Description Department of Statistics Oxford Univ. Dino Sejdinovic 
Organisation University of Oxford
Department Department of Statistics
Country United Kingdom 
Sector Academic/University 
PI Contribution Research
Collaborator Contribution Research
Impact Special Statistics-paper under revision, Bhatt,2017
Start Year 2017
 
Description Design of clinical trials to test novel entomological approaches to dengue control. CD 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Department Faculty of Epidemiology and Population Health
Country United Kingdom 
Sector Academic/University 
PI Contribution I have both statistical (including experimental design) and epidemiological expertise.
Collaborator Contribution Wolbers M (statistical programming expertise), Kleinschmidt I (expertise in stepped wedge design), Simmons CP (dengue epidemiology expertise)
Impact Paper in press: Wolbers M, Kleinschmidt I, Simmons CP and Donnelly CA. Considerations in the design of clinical trials to test novel entomological approaches to dengue control. PLoS Neglected Tropical Diseases in press.
Start Year 2011
 
Description Design of clinical trials to test novel entomological approaches to dengue control. CD 
Organisation University of Oxford
Department Centre for Clinical Vaccinology and Tropical Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution I have both statistical (including experimental design) and epidemiological expertise.
Collaborator Contribution Wolbers M (statistical programming expertise), Kleinschmidt I (expertise in stepped wedge design), Simmons CP (dengue epidemiology expertise)
Impact Paper in press: Wolbers M, Kleinschmidt I, Simmons CP and Donnelly CA. Considerations in the design of clinical trials to test novel entomological approaches to dengue control. PLoS Neglected Tropical Diseases in press.
Start Year 2011
 
Description Design of clinical trials to test novel entomological approaches to dengue control. CD 
Organisation University of Oxford
Department Oxford University Clinical Research Unit Vietnam (OUCRU)
Country Viet Nam 
Sector Academic/University 
PI Contribution I have both statistical (including experimental design) and epidemiological expertise.
Collaborator Contribution Wolbers M (statistical programming expertise), Kleinschmidt I (expertise in stepped wedge design), Simmons CP (dengue epidemiology expertise)
Impact Paper in press: Wolbers M, Kleinschmidt I, Simmons CP and Donnelly CA. Considerations in the design of clinical trials to test novel entomological approaches to dengue control. PLoS Neglected Tropical Diseases in press.
Start Year 2011
 
Description Dr Halimatou Diawara and Prof Alassane Dicko. 
Organisation University of Bamako
Department Malaria Research and Training Centre (MRTC) Bamako
Country Mali 
Sector Academic/University 
PI Contribution PhD supervisor
Collaborator Contribution PhD supervisor, primary data collection, access to Malian health policy makers
Impact forthcoming publications
Start Year 2015
 
Description ECDC 
Organisation European Centre for Disease Prevention and Control (ECDC)
Country European Union (EU) 
Sector Public 
PI Contribution Review of the national and local experiences on school closures during the 2009 H1N1 pandemic
Collaborator Contribution Access to data on school closures during the 2009 H1N1 pandemic for use in the development of new analysis tools and methods.
Impact a manuscript is in preparation, presentation to ECDC
Start Year 2010
 
Description ESP - 2015 
Organisation Global Fund to Fight AIDS, Tuberculosis and Malaria
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution Support for Elimination Scenario Planning exercises using modelling to support strategic planning in endemic countries
Collaborator Contribution Support for the country process and provision of local data
Impact Forthcoming
Start Year 2015
 
Description Economic modelling of TB in hard to reach groups PW 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution Health economic transmission-dynamic modelling
Collaborator Contribution Analysis of data from TB surveillance
Impact Report for NICE Statistics Public health Clinical medicine
Start Year 2010
 
Description Efficacy of masks to prevent influenza transmission - 2012 
Organisation University of New South Wales
Country Australia 
Sector Academic/University 
PI Contribution statistical analysis
Collaborator Contribution provision of data and intellectual input
Impact 19193267
Start Year 2008
 
Description EliminateDengue NF 2012 
Organisation Monash University
Department Eliminate Dengue Program
Country Australia 
Sector Academic/University 
PI Contribution Contributing modelling expertise to the development of Wolbachia as a novel vector control for dengue
Collaborator Contribution Other aspects of the development of the Wolbachia system
Impact Pending (papers submitted)
Start Year 2011
 
Description Estimating burden of influenza in USA - 2014 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution Developing model to assist CDC in interpreting their surveillance systems
Collaborator Contribution Providing data and expertise
Impact Papers in progress: collaboration with public health officials at CDC
Start Year 2013
 
Description Estimating burden of influenza in USA - 2014 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution Developing model to assist CDC in interpreting their surveillance systems
Collaborator Contribution Providing data and expertise
Impact Paper published, collaboraiton with public health officials at CDC
Start Year 2013
 
Description Estimation of HIV transmission dynamics using genomic sequences-2013 
Organisation Michigan State University
Department Department of Community Health
Country United States 
Sector Academic/University 
PI Contribution All analysis of data first author on PMID: 22761556
Collaborator Contribution provision of anonymised data set.
Impact PMID: 22761556
Start Year 2010
 
Description Evaluation of the London TB Find and Treat Project PW 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution Health economic transmission-dynamic modelling
Collaborator Contribution Analysis of data from TB surveillance and the Find & Treat service
Impact Jit et al. British Medical Journal 2011; 343: d5376. Reports for Department of Health
Start Year 2010
 
Description Ex Flu-2013 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution Sample design
Collaborator Contribution Alison Aiello: Principal Investigator Amanda Simanek: Study coordination, subject interaction Arnold Monto: Senior study coordinator
Impact none yet
Start Year 2011
 
Description FIND Diagnostics India - 2015 
Organisation FIND Diagnostics (India)
Country Switzerland 
Sector Public 
PI Contribution Contributed statistical analysis to "Use of Xpert MTB/RIF in Decentralized Public Health Settings and Its Effect on Pulmonary TB and DR-TB Case Finding in India" and led the modelling efforts for the publication "The Potential Impact of Up-Front Drug Sensitivity Testing on India's Epidemic of Multi-Drug Resistant Tuberculosis"
Collaborator Contribution Co-authored several papers
Impact One paper published, one in review, and one in preparation stage.
Start Year 2015
 
Description Flu Vaccination programme efficacy modelling-2013 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution Assessment of transmission model.
Collaborator Contribution Assessment of transmission model.
Impact Paper to report on this work is in publication.
Start Year 2012
 
Description FluScape Liverpool (2014) 
Organisation University of Liverpool
Country United Kingdom 
Sector Academic/University 
PI Contribution Helped to win grants and publish papers
Collaborator Contribution Helped to win grants and publish papers
Impact Several papers published.
Start Year 2008
 
Description Fluscape GZ12 (2013) 
Organisation Guangzhou No. 12 People's Hospital
Country China 
Sector Hospitals 
PI Contribution Analysis
Collaborator Contribution Field work
Impact none yet
Start Year 2009
 
Description Fluscape JHU (2013) 
Organisation Johns Hopkins University
Country United States 
Sector Academic/University 
PI Contribution Analysis
Collaborator Contribution Analysis
Impact none yet
Start Year 2009
 
Description GAVI Alliance 
Organisation Bill and Melinda Gates Foundation
Department Global Alliance for Vaccination and Immunisation (GAVI)
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution (2016) Established Vaccine Impact Modelling Consortium to provide vaccine impact estimates to Gavi and improve used models. (2017) Gavi Alliance (yellow fever)/ Olivia Bullock (2016-Dec 2017) and now Holly Prudden (Since Jan 2018)
Collaborator Contribution Provide funding and contacts to modelling groups
Impact Montagu -delivery platform for vaccine impact estimates; vaccine impact estimates - still in progress - to have the full set of this update by the end of March - Funders will use these estimates for communication fundraising and shaping policy
Start Year 2016
 
Description GFATM (Erik Volz consultancy) - 2015 
Organisation Global Fund to Fight AIDS, Tuberculosis and Malaria
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution Modelling the impact of treatment-as-prevention on HIV in Nigeria and the role of concentrated transmission in high risk groups.
Collaborator Contribution Provision of questions and data
Impact Paper and a policy brief which are currently in review.
Start Year 2015
 
Description GFATM - 2015 
Organisation Global Fund to Fight AIDS, Tuberculosis and Malaria
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution Collaboration on modelling malaria to inform the investment case, 2017-2022 strategy refresh and allocation formula
Collaborator Contribution Provision of questions and data
Impact Forthcoming
Start Year 2015
 
Description GSK - 2013 
Organisation GlaxoSmithKline (GSK)
Department GSK Biologicals SA
Country Belgium 
Sector Private 
PI Contribution Understanding biological mechanisms in the RTS,S vaccine and implications for public health impact
Collaborator Contribution Provision of data from all Phase II studies
Impact PMID 23613845; PMID 23454164, PMID 25012228; One submitted publication; Multiple conference presentations
Start Year 2011
 
Description Global lineages 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Data analysis and laboratory work
Collaborator Contribution Data provision
Impact Publications
Start Year 2012
 
Description HIV Modelling 
Organisation University of North Carolina at Chapel Hill
Country United States 
Sector Academic/University 
PI Contribution On-going collaboration to develop HIV transmission models
Collaborator Contribution academic collaboration and provision of HIV data.
Impact 19367154
Start Year 2007
 
Description HIV Modelling Consortium (2014) 
Organisation Brown University
Country United States 
Sector Academic/University 
PI Contribution The HIV Modelling Consortium leads the coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Its central objective is to help improve scientific support for decision-making by coordinating a wide range of research activities in the mathematical modelling of the HIV epidemic.
Collaborator Contribution Research activities in the mathematical modelling of the HIV epidemic.
Impact Coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Improved scientific support for decision-making with regard to the HIV epidemic.
Start Year 2010
 
Description HIV Modelling Consortium (2014) 
Organisation Harvard University
Country United States 
Sector Academic/University 
PI Contribution The HIV Modelling Consortium leads the coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Its central objective is to help improve scientific support for decision-making by coordinating a wide range of research activities in the mathematical modelling of the HIV epidemic.
Collaborator Contribution Research activities in the mathematical modelling of the HIV epidemic.
Impact Coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Improved scientific support for decision-making with regard to the HIV epidemic.
Start Year 2010
 
Description HIV Modelling Consortium (2014) 
Organisation Indiana University
Country United States 
Sector Academic/University 
PI Contribution The HIV Modelling Consortium leads the coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Its central objective is to help improve scientific support for decision-making by coordinating a wide range of research activities in the mathematical modelling of the HIV epidemic.
Collaborator Contribution Research activities in the mathematical modelling of the HIV epidemic.
Impact Coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Improved scientific support for decision-making with regard to the HIV epidemic.
Start Year 2010
 
Description HIV Modelling Consortium (2014) 
Organisation International Epidemiologic Databases to Evaluate AIDS (IeDEA)
Country Global 
Sector Charity/Non Profit 
PI Contribution The HIV Modelling Consortium leads the coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Its central objective is to help improve scientific support for decision-making by coordinating a wide range of research activities in the mathematical modelling of the HIV epidemic.
Collaborator Contribution Research activities in the mathematical modelling of the HIV epidemic.
Impact Coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Improved scientific support for decision-making with regard to the HIV epidemic.
Start Year 2010
 
Description HIV Modelling Consortium (2014) 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution The HIV Modelling Consortium leads the coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Its central objective is to help improve scientific support for decision-making by coordinating a wide range of research activities in the mathematical modelling of the HIV epidemic.
Collaborator Contribution Research activities in the mathematical modelling of the HIV epidemic.
Impact Coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Improved scientific support for decision-making with regard to the HIV epidemic.
Start Year 2010
 
Description HIV Modelling Consortium (2014) 
Organisation Ministry of Defence (MOD)
Country United Kingdom 
Sector Public 
PI Contribution The HIV Modelling Consortium leads the coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Its central objective is to help improve scientific support for decision-making by coordinating a wide range of research activities in the mathematical modelling of the HIV epidemic.
Collaborator Contribution Research activities in the mathematical modelling of the HIV epidemic.
Impact Coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Improved scientific support for decision-making with regard to the HIV epidemic.
Start Year 2010
 
Description HIV Modelling Consortium (2014) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution The HIV Modelling Consortium leads the coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Its central objective is to help improve scientific support for decision-making by coordinating a wide range of research activities in the mathematical modelling of the HIV epidemic.
Collaborator Contribution Research activities in the mathematical modelling of the HIV epidemic.
Impact Coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Improved scientific support for decision-making with regard to the HIV epidemic.
Start Year 2010
 
Description HIV Modelling Consortium (2014) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution The HIV Modelling Consortium leads the coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Its central objective is to help improve scientific support for decision-making by coordinating a wide range of research activities in the mathematical modelling of the HIV epidemic.
Collaborator Contribution Research activities in the mathematical modelling of the HIV epidemic.
Impact Coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Improved scientific support for decision-making with regard to the HIV epidemic.
Start Year 2010
 
Description HIV Modelling Consortium (2014) 
Organisation University of North Carolina at Chapel Hill
Country United States 
Sector Academic/University 
PI Contribution The HIV Modelling Consortium leads the coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Its central objective is to help improve scientific support for decision-making by coordinating a wide range of research activities in the mathematical modelling of the HIV epidemic.
Collaborator Contribution Research activities in the mathematical modelling of the HIV epidemic.
Impact Coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Improved scientific support for decision-making with regard to the HIV epidemic.
Start Year 2010
 
Description HIV Modelling Consortium (2014) 
Organisation University of York
Country United Kingdom 
Sector Academic/University 
PI Contribution The HIV Modelling Consortium leads the coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Its central objective is to help improve scientific support for decision-making by coordinating a wide range of research activities in the mathematical modelling of the HIV epidemic.
Collaborator Contribution Research activities in the mathematical modelling of the HIV epidemic.
Impact Coordinated interaction between modelling groups and policy makers, in conjunction with the targeted and responsive commissioning of new work. Improved scientific support for decision-making with regard to the HIV epidemic.
Start Year 2010
 
Description HIV Monitoring Foundation - Prof Peter Reiss - 2015 
Organisation HIV Monitoring Foundation (SHM)
Country Netherlands 
Sector Charity/Non Profit 
PI Contribution Modelling and phylogenetics
Collaborator Contribution Clinical data and epidemiological monitoring
Impact PMID: 26558543, 26529093, 26738795
 
Description HIV estimation in Europe 
Organisation Academic Medical Center
Country Netherlands 
Sector Academic/University 
PI Contribution statistical and modelling techniques for estimating HIV transmission
Collaborator Contribution access to data on HIV transmission in Europeaccess to data on HIV transmission in Europe
Impact Estimating the risk of HIV transmission from homosexual men receiving treatment to their HIV-uninfected partners. Hallett TB, Smit C, Garnett GP, de Wolf F. Sex Transm Infect. 2010 Jul 18.
Start Year 2010
 
Description HIV estimation in Europe 
Organisation University of Bern
Country Switzerland 
Sector Academic/University 
PI Contribution statistical and modelling techniques for estimating HIV transmission
Collaborator Contribution access to data on HIV transmission in Europeaccess to data on HIV transmission in Europe
Impact Estimating the risk of HIV transmission from homosexual men receiving treatment to their HIV-uninfected partners. Hallett TB, Smit C, Garnett GP, de Wolf F. Sex Transm Infect. 2010 Jul 18.
Start Year 2010
 
Description HIV treatment as prevention 
Organisation Harvard University
Department Harvard T.H. Chan School of Public Health
Country United States 
Sector Academic/University 
PI Contribution Development and fitting of mathematical models to inform policy
Collaborator Contribution Provision of data
Impact increased data sharing and intellectual collaboration
Start Year 2009
 
Description HPTN071 PopART 
Organisation PoPART Consortium
Country France 
Sector Public 
PI Contribution Economic evaluation of the PopART intervention
Collaborator Contribution Multi-disciplinary work with integrating an individual based disease transmission model
Impact One pub in Lancet Global Health and others to be submitted soon
Start Year 2012
 
Description Harvard Flu Surveillance Partnership 
Organisation Harvard University
Country United States 
Sector Academic/University 
PI Contribution expertise in statistical methods
Collaborator Contribution expertise in web-based disease surveillance
Impact creation of web based epidemic surveillance software - publication pending.
Start Year 2009
 
Description Healthsites.io 
Organisation Healthsites.io
Country France 
Sector Private 
PI Contribution Gather data from various sources and build a model to estimate a risk of transmission of a pathogen from one country to another
Collaborator Contribution Collect and provide data on healthcare facilities
Impact N/A
Start Year 2016
 
Description IHME 
Organisation Institute for Health Metrics and Evaluation (IHME)
Country United States 
Sector Charity/Non Profit 
PI Contribution Research
Collaborator Contribution Research
Impact 2 papers accepted - Nature
Start Year 2017
 
Description IRSS- Burkina Faso 
Organisation Institute of Research in Health Sciences
Country Burkina Faso 
Sector Public 
PI Contribution PI on a succesful MRC programme grant investigating mosquito biology and evaluation of control interventions. Provided technical and analytical training to Burkinabe scientists
Collaborator Contribution Field team in Burkina running major field component of an MRC programme grant
Impact none yet
Start Year 2017
 
Description IRSS- Institut de Recherche en Science de la Sante - Burkina Faso 
Organisation Research Institute for Health Sciences (IRSS)
Country Burkina Faso 
Sector Public 
PI Contribution PI on a succesful MRC programme grant investigating mosquito biology and evaluation of control interventions. Provided technical and analytical training to Burkinabe scientists
Collaborator Contribution Nothing to report
Impact Nothing to report
Start Year 2017
 
Description Influenza in China 
Organisation China Centre for Disease Control
Country China 
Sector Public 
PI Contribution Expertise in the epidemiological/statistical analysis and modelling of influenza.
Collaborator Contribution Exchange of existing data and collection of new data on mobility in China
Impact Exchange of existing data, collection of new data on mobility in China and building modelling capacity in China
Start Year 2007
 
Description Influenza transmission in Singapore 
Organisation Tan Tock Seng Hospital
Country Singapore 
Sector Hospitals 
PI Contribution Support for fellowship (mentor and collaborators) to develop and apply models of influenza transmission in Singapore. Also an on-going collaboration on STD modelling
Collaborator Contribution provision of influenza data from Singapore.
Impact Increased mathematical modelling capacity at the National University of Singapore
Start Year 2009
 
Description Institut Pasteur - Herve Bourhy 
Organisation Pasteur Institute, Paris
Department Laboratory Lysavirus Dynamics and Host Adaptation
Country France 
Sector Charity/Non Profit 
PI Contribution Analyse data
Collaborator Contribution Provide data
Impact Supervise an MSc student, workshop on rabies in Cameroon (Dec 2016)
Start Year 2014
 
Description Institut Pasteur - Simon Cauchemez 
Organisation Pasteur Institute, Paris
Country France 
Sector Academic/University 
PI Contribution Analyse data on MERS-CoV virus
Collaborator Contribution Analyse data on MERS-CoV virus
Impact doi: 10.1073/pnas.1519235113
Start Year 2014
 
Description Institute for Disease Modelling in Seattle. Phil Ekhoff 
Organisation Intellectual Ventures
Country United States 
Sector Private 
PI Contribution Bringing spatial expertise to outbreak mapping
Collaborator Contribution Josh Procter and Phil Ekhoff. Core new method for outbreak mapping
Impact Various presentations IVCC invited speaker. RBM. 1 paper under review submitted Nature Communications (still to be published)
Start Year 2016
 
Description Institute of human virology - similar to global fund 
Organisation University of Maryland
Country United States 
Sector Academic/University 
PI Contribution Modelling the impact of treatment-as-prevention on HIV in Nigeria and the role of concentrated transmission in high risk groups.
Collaborator Contribution Modelling the impact of treatment-as-prevention on HIV in Nigeria and the role of concentrated transmission in high risk groups.
Impact Paper and a policy brief which are currently in review.
Start Year 2016
 
Description Interferon gamma tests for the rapid identification of active tuberculosis disease PW 
Organisation Brunel University London
Country United Kingdom 
Sector Academic/University 
PI Contribution Transmission-dynamic modelling
Collaborator Contribution Clinical research Statistical analysis Health economics
Impact No outputs yet Statistics Public health Clinical medicine Health economics
Start Year 2011
 
Description Interferon gamma tests for the rapid identification of active tuberculosis disease PW 
Organisation Imperial College London
Department Faculty of Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution Transmission-dynamic modelling
Collaborator Contribution Clinical research Statistical analysis Health economics
Impact No outputs yet Statistics Public health Clinical medicine Health economics
Start Year 2011
 
Description Interferon gamma tests for the rapid identification of active tuberculosis disease PW 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution Transmission-dynamic modelling
Collaborator Contribution Clinical research Statistical analysis Health economics
Impact No outputs yet Statistics Public health Clinical medicine Health economics
Start Year 2011
 
Description Interferon gamma tests for the rapid identification of active tuberculosis disease PW 
Organisation Queen Mary University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Transmission-dynamic modelling
Collaborator Contribution Clinical research Statistical analysis Health economics
Impact No outputs yet Statistics Public health Clinical medicine Health economics
Start Year 2011
 
Description Interferon gamma tests for the rapid identification of active tuberculosis disease PW 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Transmission-dynamic modelling
Collaborator Contribution Clinical research Statistical analysis Health economics
Impact No outputs yet Statistics Public health Clinical medicine Health economics
Start Year 2011
 
Description Interpretation of flu serology SC 
Organisation University of Oxford
Department Oxford University Clinical Research Unit Vietnam (OUCRU)
Country Viet Nam 
Sector Academic/University 
PI Contribution New method to interprete influenza serological data. Better quantify measurement errors and assess their impact on estimates of influenza attack rates.
Collaborator Contribution Provide data
Impact 1 paper in press in plos pathogens
Start Year 2010