Prevention of dementia by targeting risk factors
Lead Research Organisation:
University College London
Department Name: Epidemiology and Public Health
Abstract
Lack of understanding of the drivers of neurodegeneration and confusion of the causes and consequences of the disease due to the long latent phase of dementia have been major contributors to the large number of unsuccessful drug and lifestyle trials for dementia. The Lancet 2017 Commission on dementia prevention recommended targeting 9 risk factors to prevent dementia, but the expert group acknowledge that limitations in evidence, such as reverse causation bias, may affect these conclusions. We propose an ambitious programme of work which will evaluate risk factors that can be used to prevent dementia via health policy interventions, and will examine a wide range of plasma metabolites that can be used as early dementia biomarkers and candidates for disease-modifying dementia treatments. The objectives of our multi-cohort research programme are to: (1) examine associations of the Lancet 2017 Commission risk factors with cognitive decline, clinically-verified Alzheimer's disease and dementia using the largest individual-participant dataset in this field and a novel analytic strategy to account for bias due to reverse causation; (2) expand analyses to examine how trajectories of chronic diseases over the adult lifecourse shape risk of dementia; and (3) evaluate 233 metabolite biomarkers, singly and in combination, as early predictors of cognitive function, Alzheimer's disease and dementia, with a focus on biomarkers assessed at least 10 years before dementia diagnosis. The sources of data used in the analysis include the IPD-Work consortium of 43 cohort studies, the Dementia Platform UK cohort data resource, UK Biobank, the US-European metabolomics-dementia consortium of 11 studies, and the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium, in total of >1.5 million adults from the UK and elsewhere. This programme is timely because robust evidence must be generated before progress toward effective therapeutic interventions can be made.
Technical Summary
The objectives of our multi-cohort research programme are to: (1) examine associations of the Lancet 2017 Commission risk factors with cognitive decline, clinically-verified Alzheimer's disease and dementia using the largest individual-participant dataset in this field and a novel analytic strategy to account for bias due to reverse causation; (2) expand analyses to examine how trajectories of chronic diseases over the adult lifecourse shape risk of dementia; and (3) evaluate 233 metabolite biomarkers, singly and in combination, as early predictors of cognitive function, Alzheimer's disease and dementia, with a focus on biomarkers assessed at least 10 years before dementia diagnosis. This programme is based on existing data related to very large numbers of people with long follow-up (N up to 1.5 million), allowing to examine the temporality underpinning the established associations between risk factors, biomarkers and dementia. The sources of data include the IPD-Work consortium, DPUK, UK Biobank, the US-European metabolomics-dementia consortium, and the UCLEB consortium. Our analytic approach emphasises the importance of "time windows" when considering the role of risk factors and biomarkers for dementia. Thus, we stratify analyses by length of time between risk factor assessment and onset of dementia, assuming that the closer the risk factor/biomarker assessment is to the onset of clinical dementia, the greater the possibility the risk factors are a consequence of preclinical dementia rather than a cause. Resources are requested for research data curation and harmonisation across cohort studies, data analysis, administration and travel.
Planned Impact
We will seek to maximise our project's impact by involving lay and professional partners in steering and shaping the research, disseminating the findings to academic and non-academic beneficiaries, and working with beneficiaries to support changes to policy and practice.
Dementia patients, carers and the public: The benefits to the public of the proposed multi-cohort analysis relate to the generation of robust evidence on modifiable risk factors for dementia and biomarkers for cognitive impairment, Alzheimer's disease and dementia than has been available previously. The datasets represent diverse populations, including occupational and general-population samples, different age groups, white- and non-white ethnicities, a wide range of socioeconomic statuses, those with high and low education, and individuals with and without genetic susceptibility to dementia. This diversity will allow us to provide evidence on the generalisability of new findings.
Policy and public health guidelines: With detailed analyses separating risk factor and biomarker assessments at a healthy state and at preclinical and clinical stages of dementia and, in addition, taking into account trajectories of diseases, the project will increase understanding of the drivers of ageing outcomes with major public health relevance, such as cognitive impairment, Alzheimer's disease, dementia and multimorbidity. This in turn will inform the development of preventative interventions and health policies across the adult life course that will expand healthy life span, and reduce the burden of ill health, disease and disability at older ages.
Beneficiaries of our programme of work will be the National Institute for Health and Care Excellence (NICE) and other organisations with guidance, advice and information services for health, public health and social care professionals; national policymakers such as those in the Department of Health, Public Health England, NHS Commissioning, Clinical Commissioning Groups, Health and Wellbeing Boards, and the Association of Directors of Public Health; Charities, such as the Alzheimer's Society; as well as those in local government, who require evidence on where to invest vital resources (e.g., the relative benefit to investment in behaviour change at different life stages); third-sector campaigning agencies (representing the older population, patient groups); and medical practitioners.
Academic capacity and funders: Large-scale epidemiological studies, such as this, have been used as primary evidence of international and national guidelines for prevention of major chronic diseases. Findings from longitudinal population studies may also highlight directions for further interventional and experimental research by identifying risk factors and biomarkers that may be important even at a population level. Such work will provide valuable information about relevant targets for prevention as well as about which stages in the adult life course remediation of the risks is possible. A further advantage is that with large data sets it is also possible to show (and publish) absence of associations convincingly and in this way help reduce investments on research and interventions that are unlikely to be successful. All this information, in combination with subsequent evidence from trials and mechanistic studies, may ultimately enable highly cost-effective dementia prevention measures to be developed.
Industry: The paradigm that has dominated dementia research to date revolves around the amyloid cascade hypothesis. After hundreds of failed trials of potential disease-modifying drugs, major pharmaceutical companies are withdrawing from research on neurodegenerative diseases. Our research aimed at identifying early (non-amyloid) biomarkers for Alzheimer's disease and dementia might provide new targets for research on disease-modifying drugs.
Dementia patients, carers and the public: The benefits to the public of the proposed multi-cohort analysis relate to the generation of robust evidence on modifiable risk factors for dementia and biomarkers for cognitive impairment, Alzheimer's disease and dementia than has been available previously. The datasets represent diverse populations, including occupational and general-population samples, different age groups, white- and non-white ethnicities, a wide range of socioeconomic statuses, those with high and low education, and individuals with and without genetic susceptibility to dementia. This diversity will allow us to provide evidence on the generalisability of new findings.
Policy and public health guidelines: With detailed analyses separating risk factor and biomarker assessments at a healthy state and at preclinical and clinical stages of dementia and, in addition, taking into account trajectories of diseases, the project will increase understanding of the drivers of ageing outcomes with major public health relevance, such as cognitive impairment, Alzheimer's disease, dementia and multimorbidity. This in turn will inform the development of preventative interventions and health policies across the adult life course that will expand healthy life span, and reduce the burden of ill health, disease and disability at older ages.
Beneficiaries of our programme of work will be the National Institute for Health and Care Excellence (NICE) and other organisations with guidance, advice and information services for health, public health and social care professionals; national policymakers such as those in the Department of Health, Public Health England, NHS Commissioning, Clinical Commissioning Groups, Health and Wellbeing Boards, and the Association of Directors of Public Health; Charities, such as the Alzheimer's Society; as well as those in local government, who require evidence on where to invest vital resources (e.g., the relative benefit to investment in behaviour change at different life stages); third-sector campaigning agencies (representing the older population, patient groups); and medical practitioners.
Academic capacity and funders: Large-scale epidemiological studies, such as this, have been used as primary evidence of international and national guidelines for prevention of major chronic diseases. Findings from longitudinal population studies may also highlight directions for further interventional and experimental research by identifying risk factors and biomarkers that may be important even at a population level. Such work will provide valuable information about relevant targets for prevention as well as about which stages in the adult life course remediation of the risks is possible. A further advantage is that with large data sets it is also possible to show (and publish) absence of associations convincingly and in this way help reduce investments on research and interventions that are unlikely to be successful. All this information, in combination with subsequent evidence from trials and mechanistic studies, may ultimately enable highly cost-effective dementia prevention measures to be developed.
Industry: The paradigm that has dominated dementia research to date revolves around the amyloid cascade hypothesis. After hundreds of failed trials of potential disease-modifying drugs, major pharmaceutical companies are withdrawing from research on neurodegenerative diseases. Our research aimed at identifying early (non-amyloid) biomarkers for Alzheimer's disease and dementia might provide new targets for research on disease-modifying drugs.
Organisations
- University College London (Lead Research Organisation)
- VU University Medical Center (Collaboration)
- Washington University in St. Louis (Collaboration)
- IMPERIAL COLLEGE LONDON (Collaboration)
- UNIVERSITY OF OXFORD (Collaboration)
- Maastricht University (UM) (Collaboration)
- SomaLogic (Collaboration)
- Janssen Research & Development (Collaboration)
- UNIVERSITY OF GLASGOW (Collaboration)
- Johns Hopkins University (Collaboration)
- Washington University School of Medicine (Collaboration)
- Johnson & Johnson (Collaboration)
- National Institutes of Health (NIH) (Collaboration)
- University Hospital Tuebingen (Collaboration)
Publications
Ding C
(2022)
Trajectories of alcohol consumption in relation to all-cause mortality in patients with cardiovascular disease: a 35-year prospective cohort study.
in Addiction (Abingdon, England)
Strandberg TE
(2022)
Plasma ceramides independently predict all-cause mortality in men aged 85.
in Age and ageing
Luotola K
(2020)
Statin treatment, phenotypic frailty and mortality among community-dwelling octogenarian men: the HBS cohort.
in Age and ageing
Singh-Manoux A
(2022)
Association between kidney function and incidence of dementia: 10-year follow-up of the Whitehall II cohort study.
in Age and ageing
Strandberg TE
(2022)
Association of plasma gelsolin with frailty phenotype and mortality among octogenarian community-dwelling men: a cohort study.
in Aging clinical and experimental research
Hassen C
(2023)
Change in lipids before onset of dementia, coronary heart disease, and mortality: A 28-year follow-up Whitehall II prospective cohort study
in Alzheimer's & Dementia
Lindbohm JV
(2022)
Plasma proteins, cognitive decline, and 20-year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies.
in Alzheimer's & dementia : the journal of the Alzheimer's Association
Sipilä PN
(2020)
Long-term risk of dementia following hospitalization due to physical diseases: A multicohort study.
in Alzheimer's & dementia : the journal of the Alzheimer's Association
Van Gennip ACE
(2023)
Age at cardiovascular disease onset, dementia risk, and the role of lifestyle factors.
in Alzheimer's & dementia : the journal of the Alzheimer's Association
Description | AMERICAN HEART ASSOCIATION: NEIGHBORHOODS AND CARDIOVASCULAR HEALTH: A SCIENTIFIC STATEMENT FROM THE AMERICAN HEART ASSOCIATION. Circulation: Cardiovasc Qual Outcomes. 2023;16:e000124. DOI: 10.1161/HCQ.0000000000000124 |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | American Heart Association is an internationally influential organisation providing clinical guidelines and policy documents for cardiovascular disease prevention. Our study was used as evidence to highlight socioeconomic risk factors affecting transitions from a healthy state to cardiovascular disease and multimorbidity. |
URL | https://www.ahajournals.org/doi/10.1161/HCQ.0000000000000124 |
Guideline Title | CLINICAL PRACTICE GUIDELINE FOR THE EVALUATION AND TREATMENT OF CHILDREN AND ADOLESCENTS WITH OBESITY. |
Description | CLINICAL PRACTICE GUIDELINE FOR THE EVALUATION AND TREATMENT OF CHILDREN AND ADOLESCENTS WITH OBESITY |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in clinical guidelines |
Impact | Our findings are used as evidence for recommendations to pay more attention to social deprivation in evaluation and treatment of children and adolescents with obesity. |
URL | https://publications.aap.org/pediatrics/article/151/2/e2022060640/190443/Clinical-Practice-Guideline... |
Guideline Title | ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD. The Task Force for diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and the European Association for the Study of Diabetes (EASD). |
Description | Citation in 2019 ESC Guidelines on Diabetes, Pre-Diabetes and Cardiovascular Disease |
Geographic Reach | Europe |
Policy Influence Type | Citation in clinical guidelines |
Impact | Our pooled evidence from 1.7 million men and women, published in the Lancet, is used by European Society of Cardiology guidelines to emphasise the importance of considering socioeconomic adversity in prevention of premature death. Failure to do so was estimated to be associated with a 2.1-year reduction in life expectancy between ages 40 and 85 years. |
URL | https://pubmed.ncbi.nlm.nih.gov/29453200/ |
Description | Citation in 2021 Scientific Statement from the American Heart Association |
Geographic Reach | North America |
Policy Influence Type | Citation in clinical reviews |
URL | https://www.ahajournals.org/doi/10.1161/CIR.0000000000000947 |
Description | Citation in ALZHEIMER'S DISEASE FACTS AND FIGURES. Special Report discussing the patient journey in an era of new treatments. Alzheimers Dement 2023;19(4) |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | American Alzheimer's Association is an important authority in dementia field, promoting brain health in the US population and internationally. Our study was used as evidence to emphasise the importance of targeting midlife obesity and high blood pressure for prevention or delay of the onset of old-age dementia. |
URL | https://www.alz.org/media/documents/alzheimers-facts-and-figures.pdf |
Description | Citation in ALZHEIMER'S DISEASE FACTS AND FIGURES. Special Report discussing the patient journey in an era of new treatments. Alzheimers Dement 2023;19(4) |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | American Alzheimer's Association is an important authority in dementia field, promoting brain health in the US population and internationally. Our study was used as evidence to emphasise the importance of targeting midlife obesity and high blood pressure for prevention or delay of the onset of old-age dementia. |
URL | https://www.alz.org/media/documents/alzheimers-facts-and-figures.pdf |
Description | Citation in ALZHEIMER'S DISEASE FACTS AND FIGURES. Special Report discussing the patient journey in an era of new treatments. Alzheimers Dement 2023;19(4) |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | American Alzheimer's Association is an important authority in dementia field, promoting brain health in the US population and internationally. Our study was used as evidence to emphasise the importance of targeting midlife obesity and high blood pressure for prevention or delay of the onset of old-age dementia. |
URL | https://www.alz.org/media/documents/alzheimers-facts-and-figures.pdf |
Description | Citation in Alzheimer's Association Report: Alzheimer's disease facts and figures (2021) |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | American Alzheimer's Association is an important authority in dementia field, promoting brain health in the US population and internationally. Our study was used as evidence to emphasise the importance of high blood pressure as a target of dementia prevention. |
URL | https://alz-journals.onlinelibrary.wiley.com/doi/epdf/10.1002/alz.12328 |
Description | Citation in Alzheimer's Association Report: Alzheimer's disease facts and figures (2021) |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | American Alzheimer's Association is an important authority in dementia field, promoting brain health in the US population and internationally. Our study was used as evidence to emphasise the importance of high blood pressure as a target of dementia prevention. |
URL | https://alz-journals.onlinelibrary.wiley.com/doi/epdf/10.1002/alz.12328 |
Description | Citation in Alzheimer's Association Report: Alzheimer's disease facts and figures (2021) |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | American Alzheimer's Association is an important authority in dementia field, promoting brain health in the US population and internationally. Our study was used as evidence to emphasise the importance of high blood pressure as a target of dementia prevention. |
URL | https://alz-journals.onlinelibrary.wiley.com/doi/epdf/10.1002/alz.12328 |
Description | Citation in American Heart Association Scientific Statement (2021) |
Geographic Reach | North America |
Policy Influence Type | Citation in other policy documents |
Impact | This American Heart Association Scientific Statement makes recommendations for cardiovascular disease prevention. Our state-of-the-art review was used as evidence to support stress management as a secondary prevention intervention for patients with cardiovascular disease. |
URL | https://www.ahajournals.org/doi/10.1161/CIR.0000000000000947?url_ver=Z39.88-2003&rfr_id=ori:rid:cros... |
Guideline Title | Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity |
Description | Citation in Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in clinical guidelines |
Impact | Our evidence shows that development of obesity from childhood to adulthood is strongly affected by socioeconomic circumstances in childhood and later in life. |
URL | https://publications.aap.org/pediatrics/article/151/2/e2022060640/190443/Clinical-Practice-Guideline... |
Guideline Title | ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Description | Citation in ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Geographic Reach | Europe |
Policy Influence Type | Citation in clinical guidelines |
Impact | European guidelines for cardiovascular disease prevention make recommendations for preventive interventions in clinical practice. Our study was used as evidence to target obesity even in the absence of otherwise adverse metabolic profile because our study shows metabolically healthy obesity in most cases progress to unhealthy obesity over time. In addition, our state-of-the-art review was used as evidence to support stress management as a secondary prevention intervention for patients with cardiovascular disease. |
URL | https://academic.oup.com/eurheartj/article/42/34/3227/6358713 |
Guideline Title | ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Description | Citation in ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Geographic Reach | Europe |
Policy Influence Type | Citation in clinical guidelines |
Impact | European guidelines for cardiovascular disease prevention make recommendations for preventive interventions in clinical practice. Our study was used as evidence to target obesity even in the absence of otherwise adverse metabolic profile because our study shows metabolically healthy obesity in most cases progress to unhealthy obesity over time. In addition, our state-of-the-art review was used as evidence to support stress management as a secondary prevention intervention for patients with cardiovascular disease. |
URL | https://academic.oup.com/eurheartj/article/42/34/3227/6358713 |
Guideline Title | ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Description | Citation in ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Geographic Reach | Europe |
Policy Influence Type | Citation in clinical guidelines |
Impact | European guidelines for cardiovascular disease prevention make recommendations for preventive interventions in clinical practice. Our study was used as evidence to target obesity even in the absence of otherwise adverse metabolic profile because our study shows metabolically healthy obesity in most cases progress to unhealthy obesity over time. In addition, our state-of-the-art review was used as evidence to support stress management as a secondary prevention intervention for patients with cardiovascular disease. |
URL | https://academic.oup.com/eurheartj/article/42/34/3227/6358713 |
Guideline Title | ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Description | Citation in ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Geographic Reach | Europe |
Policy Influence Type | Citation in clinical guidelines |
Impact | European guidelines for cardiovascular disease prevention make recommendations for preventive interventions in clinical practice. Our study was used as evidence to target obesity even in the absence of otherwise adverse metabolic profile because our study shows metabolically healthy obesity in most cases progress to unhealthy obesity over time. In addition, our state-of-the-art review was used as evidence to support stress management as a secondary prevention intervention for patients with cardiovascular disease. |
URL | https://academic.oup.com/eurheartj/article/42/34/3227/6358713 |
Guideline Title | ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Description | Citation in ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Geographic Reach | Europe |
Policy Influence Type | Citation in clinical guidelines |
Impact | European guidelines for cardiovascular disease prevention make recommendations for preventive interventions in clinical practice. Our study was used as evidence to target obesity even in the absence of otherwise adverse metabolic profile because our study shows metabolically healthy obesity in most cases progress to unhealthy obesity over time. In addition, our state-of-the-art review was used as evidence to support stress management as a secondary prevention intervention for patients with cardiovascular disease. |
URL | https://academic.oup.com/eurheartj/article/42/34/3227/6358713 |
Guideline Title | ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Description | Citation in ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Geographic Reach | Europe |
Policy Influence Type | Citation in clinical guidelines |
Impact | European guidelines for cardiovascular disease prevention make recommendations for preventive interventions in clinical practice. Our study was used as evidence to target obesity even in the absence of otherwise adverse metabolic profile because our study shows metabolically healthy obesity in most cases progress to unhealthy obesity over time. In addition, our state-of-the-art review was used as evidence to support stress management as a secondary prevention intervention for patients with cardiovascular disease. |
URL | https://academic.oup.com/eurheartj/article/42/34/3227/6358713 |
Guideline Title | ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Description | Citation in ESC Guidelines on cardiovascular disease prevention in clinical practice (2021) |
Geographic Reach | Europe |
Policy Influence Type | Citation in clinical guidelines |
Impact | European guidelines for cardiovascular disease prevention make recommendations for preventive interventions in clinical practice. Our study was used as evidence to target obesity even in the absence of otherwise adverse metabolic profile because our study shows metabolically healthy obesity in most cases progress to unhealthy obesity over time. In addition, our state-of-the-art review was used as evidence to support stress management as a secondary prevention intervention for patients with cardiovascular disease. |
URL | https://academic.oup.com/eurheartj/article/42/34/3227/6358713 |
Description | Citation in Health Equity in England Report |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Impact | Our life course analysis of all main causes of hospitalisations in relation to socioeconomic status is used as evidence in the 'Marmot Review 10 Years On' to demonstrate how coping with day-to-day shortages, facing inconveniences and adversity affect physical and mental health in negative ways. |
URL | https://www.health.org.uk/publications/reports/the-marmot-review-10-years-on |
Description | Citation in Health Equity in England Report |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Impact | Our life course analysis of all main causes of hospitalisations in relation to socioeconomic status is used as evidence in the 'Marmot Review 10 Years On' to demonstrate how coping with day-to-day shortages, facing inconveniences and adversity affect physical and mental health in negative ways. |
URL | https://www.health.org.uk/publications/reports/the-marmot-review-10-years-on |
Description | Citation in Heart Disease and Stroke Statistics-Update (2023) A Report from the American Heart Association. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our evidence demonstrates the importance of targeting occupational and lifestyle factors in order to prevent cardiovascular disease and delay progression of these diseases. |
URL | https://www.ahajournals.org/doi/10.1161/CIR.0000000000001123?url_ver=Z39.88-2003&rfr_id=ori:rid:cros... |
Description | Citation in Heart Disease and Stroke Statistics-Update (2023) A Report from the American Heart Association. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our evidence demonstrates the importance of targeting occupational and lifestyle factors in order to prevent cardiovascular disease and delay progression of these diseases. |
URL | https://www.ahajournals.org/doi/10.1161/CIR.0000000000001123?url_ver=Z39.88-2003&rfr_id=ori:rid:cros... |
Description | Citation in Heart Disease and Stroke Statistics-Update (2023) A Report from the American Heart Association. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our evidence demonstrates the importance of targeting occupational and lifestyle factors in order to prevent cardiovascular disease and delay progression of these diseases. |
URL | https://www.ahajournals.org/doi/10.1161/CIR.0000000000001123?url_ver=Z39.88-2003&rfr_id=ori:rid:cros... |
Description | Citation in Heart Disease and Stroke Statistics-Update: A Report from the American Heart Association. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our evidence demonstrates the importance of targeting occupational and lifestyle factors in order to prevent cardiovascular disease and delay progression of these diseases. |
URL | https://www.ahajournals.org/doi/10.1161/CIR.0000000000001123?url_ver=Z39.88-2003&rfr_id=ori:rid:cros... |
Description | Citation in Heart Disease and Stroke Statistics-Update: A Report from the American Heart Association. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our evidence demonstrates the importance of targeting occupational and lifestyle factors in order to prevent cardiovascular disease and delay progression of these diseases. |
URL | https://www.ahajournals.org/doi/10.1161/CIR.0000000000001123?url_ver=Z39.88-2003&rfr_id=ori:rid:cros... |
Description | Citation in Heart Disease and Stroke Statistics-Update: A Report from the American Heart Association. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our evidence demonstrates the importance of targeting occupational and lifestyle factors in order to prevent cardiovascular disease and delay progression of these diseases. |
URL | https://www.ahajournals.org/doi/10.1161/CIR.0000000000001123?url_ver=Z39.88-2003&rfr_id=ori:rid:cros... |
Description | Citation in Public Health England COVID-19 prevention recommendations |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Impact | TBA |
URL | https://www.gov.uk/government/publications/excess-weight-and-covid-19-insights-from-new-evidence |
Guideline Title | Recommendations for Primary Prevention of Cardiovascular Disease in Women: JACC State-of-the-Art Review |
Description | Citation in Recommendations for Primary Prevention of Cardiovascular Disease |
Geographic Reach | North America |
Policy Influence Type | Citation in clinical guidelines |
Impact | Our multicohort analyses and state-of-the-art review are used to justify American College of Cardiology recommendation to assess psychological factors in primary prevention of cardiovascular disease among women. The estimated reduction of cardiovascular disease attributable to successful interventions of these risk factors is approximately 3%. |
Description | Citation in The Lancet Commission on Dementia: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our individual-level meta-analyses of up to 1.3 million people and data from 2- to 3-decade follow-up of UK men and women are used as key evidence to justify recommendations to maintain normal weight, keep systolic blood pressure below 130mmHg and avoid consuming alcohol more than 21 units per week in midlife to prevent old-age dementia, a disease for which there is no disease-modifying medication. The estimated reduction of dementia attributable to the elimination of these risk factors is 3.4%. |
URL | https://pubmed.ncbi.nlm.nih.gov/29901708/ |
Description | Citation in The Lancet Commission on Dementia: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our individual-level meta-analyses of up to 1.3 million people and data from 2- to 3-decade follow-up of UK men and women are used as key evidence to justify recommendations to maintain normal weight, keep systolic blood pressure below 130mmHg and avoid consuming alcohol more than 21 units per week in midlife to prevent old-age dementia, a disease for which there is no disease-modifying medication. The estimated reduction of dementia attributable to the elimination of these risk factors is 3.4%. |
URL | https://pubmed.ncbi.nlm.nih.gov/30995986/ |
Description | Citation in The Lancet Commission on Dementia: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our individual-level meta-analyses of up to 1.3 million people and data from 2- to 3-decade follow-up of UK men and women are used as key evidence to justify recommendations to maintain normal weight, keep systolic blood pressure below 130mmHg and avoid consuming alcohol more than 21 units per week in midlife to prevent old-age dementia, a disease for which there is no disease-modifying medication. The estimated reduction of dementia attributable to the elimination of these risk factors is 3.4%. |
URL | https://pubmed.ncbi.nlm.nih.gov/30068508/ |
Description | Citation in The Lancet Commission on Dementia: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our individual-level meta-analyses of up to 1.3 million people and data from 2- to 3-decade follow-up of UK men and women are used as key evidence to justify recommendations to maintain normal weight, keep systolic blood pressure below 130mmHg and avoid consuming alcohol more than 21 units per week in midlife to prevent old-age dementia, a disease for which there is no disease-modifying medication. The estimated reduction of dementia attributable to the elimination of these risk factors is 3.4%. |
URL | https://pubmed.ncbi.nlm.nih.gov/31374073/ |
Description | Citation in The Lancet Commission on Dementia: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our individual-level meta-analyses of up to 1.3 million people and data from 2- to 3-decade follow-up of UK men and women are used as key evidence to justify recommendations to maintain normal weight, keep systolic blood pressure below 130mmHg and avoid consuming alcohol more than 21 units per week in midlife to prevent old-age dementia, a disease for which there is no disease-modifying medication. The estimated reduction of dementia attributable to the elimination of these risk factors is 3.4%. |
URL | https://pubmed.ncbi.nlm.nih.gov/28943197/ |
Description | Citation in The Lancet Commission on Dementia: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our individual-level meta-analyses of up to 1.3 million people and data from 2- to 3-decade follow-up of UK men and women are used as key evidence to justify recommendations to maintain normal weight, keep systolic blood pressure below 130mmHg and avoid consuming alcohol more than 21 units per week in midlife to prevent old-age dementia, a disease for which there is no disease-modifying medication. The estimated reduction of dementia attributable to the elimination of these risk factors is 3.4%. |
URL | https://pubmed.ncbi.nlm.nih.gov/28642251/ |
Description | Citation in The Lancet Commission on Dementia: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our individual-level meta-analyses of up to 1.3 million people and data from 2- to 3-decade follow-up of UK men and women are used as key evidence to justify recommendations to maintain normal weight, keep systolic blood pressure below 130mmHg and avoid consuming alcohol more than 21 units per week in midlife to prevent old-age dementia, a disease for which there is no disease-modifying medication. The estimated reduction of dementia attributable to the elimination of these risk factors is 3.4%. |
URL | https://pubmed.ncbi.nlm.nih.gov/28679494/ |
Description | Citation in The Lancet Commission on Dementia: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our individual-level meta-analyses of up to 1.3 million people and data from 2- to 3-decade follow-up of UK men and women are used as key evidence to justify recommendations to maintain normal weight, keep systolic blood pressure below 130mmHg and avoid consuming alcohol more than 21 units per week in midlife to prevent old-age dementia, a disease for which there is no disease-modifying medication. The estimated reduction of dementia attributable to the elimination of these risk factors is 3.4%. |
URL | https://pubmed.ncbi.nlm.nih.gov/31391187/ |
Description | Citation in The Lancet Commission on Dementia: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our individual-level meta-analyses of up to 1.3 million people and data from 2- to 3-decade follow-up of UK men and women are used as key evidence to justify recommendations to maintain normal weight, keep systolic blood pressure below 130mmHg and avoid consuming alcohol more than 21 units per week in midlife to prevent old-age dementia, a disease for which there is no disease-modifying medication. The estimated reduction of dementia attributable to the elimination of these risk factors is 3.4%. |
URL | https://pubmed.ncbi.nlm.nih.gov/30860560/ |
Description | Citation in WHO European Regional Obesity Report. |
Geographic Reach | Europe |
Policy Influence Type | Citation in other policy documents |
Impact | Our analyses of data across multiple continents demonstrate the important role of social determinants of health, including metabolic health. |
URL | https://apps.who.int/iris/bitstream/handle/10665/353747/9789289057738-eng.pdf |
Description | Citation in WHO/ILO Review on Work-related Burden of Disease and Injury (Stroke): Environment International 142 (2020) 105746. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our systematic review and individual-level meta-analysis provides the main evidence base for the WHO/ILO Joint Estimates on the adverse effects of extensive working hours on the risk of stroke. WHO/ILO Joint Estimates are used in international and national recommendations and policies to reduce work-related hazards. |
URL | https://pubmed.ncbi.nlm.nih.gov/22473079/ |
Description | Citation in WHO/ILO Review on Work-related Burden of Disease and Injury (Stroke): Environment International 142 (2020) 105746. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our systematic review and individual-level meta-analysis provides the main evidence base for the WHO/ILO Joint Estimates on the adverse effects of extensive working hours on the risk of stroke. WHO/ILO Joint Estimates are used in international and national recommendations and policies to reduce work-related hazards. |
URL | https://pubmed.ncbi.nlm.nih.gov/25587065/ |
Description | Citation in WHO/ILO Review on Work-related Burden of Disease and Injury (Stroke): Environment International 142 (2020) 105746. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our systematic review and individual-level meta-analysis provides the main evidence base for the WHO/ILO Joint Estimates on the adverse effects of extensive working hours on the risk of stroke. WHO/ILO Joint Estimates are used in international and national recommendations and policies to reduce work-related hazards. |
URL | https://pubmed.ncbi.nlm.nih.gov/26298822/ |
Description | Citation in WHO/ILO Review on Work-related Burden of Disease and Injury (Stroke): Environment International 142 (2020) 105746. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our systematic review and individual-level meta-analysis provides the main evidence base for the WHO/ILO Joint Estimates on the adverse effects of extensive working hours on the risk of stroke. WHO/ILO Joint Estimates are used in international and national recommendations and policies to reduce work-related hazards. |
URL | https://pubmed.ncbi.nlm.nih.gov/25654401/ |
Description | Citation in WHO/ILO Review on Work-related Burden of Disease and Injury (Stroke): Environment International 142 (2020) 105746. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our systematic review and individual-level meta-analysis provides the main evidence base for the WHO/ILO Joint Estimates on the adverse effects of extensive working hours on the risk of stroke. WHO/ILO Joint Estimates are used in international and national recommendations and policies to reduce work-related hazards. |
URL | https://pubmed.ncbi.nlm.nih.gov/25262544/ |
Description | Citation in WHO/ILO Review on Work-related Burden of Disease and Injury (Stroke): Environment International 142 (2020) 105746. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our systematic review and individual-level meta-analysis provides the main evidence base for the WHO/ILO Joint Estimates on the adverse effects of extensive working hours on the risk of stroke. WHO/ILO Joint Estimates are used in international and national recommendations and policies to reduce work-related hazards. |
URL | https://pubmed.ncbi.nlm.nih.gov/23297662/ |
Description | Citation in WHO/ILO Review on Work-related Burden of Disease and Injury (Stroke): Environment International 142 (2020) 105746. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our systematic review and individual-level meta-analysis provides the main evidence base for the WHO/ILO Joint Estimates on the adverse effects of extensive working hours on the risk of stroke. WHO/ILO Joint Estimates are used in international and national recommendations and policies to reduce work-related hazards. |
URL | https://pubmed.ncbi.nlm.nih.gov/30276493/ |
Description | Citation in WHO/ILO Review on Work-related Burden of Disease and Injury (Stroke): Environment International 142 (2020) 105746. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our systematic review and individual-level meta-analysis provides the main evidence base for the WHO/ILO Joint Estimates on the adverse effects of extensive working hours on the risk of stroke. WHO/ILO Joint Estimates are used in international and national recommendations and policies to reduce work-related hazards. |
URL | https://pubmed.ncbi.nlm.nih.gov/19544749/ |
Description | Citation in WHO/ILO Review on Work-related Burden of Disease and Injury (Stroke): Environment International 142 (2020) 105746. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our systematic review and individual-level meta-analysis provides the main evidence base for the WHO/ILO Joint Estimates on the adverse effects of extensive working hours on the risk of stroke. WHO/ILO Joint Estimates are used in international and national recommendations and policies to reduce work-related hazards. |
URL | https://pubmed.ncbi.nlm.nih.gov/22952309/ |
Description | Citation in WHO/ILO Review on Work-related Burden of Disease and Injury (Stroke): Environment International 142 (2020) 105746. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our systematic review and individual-level meta-analysis provides the main evidence base for the WHO/ILO Joint Estimates on the adverse effects of extensive working hours on the risk of stroke. WHO/ILO Joint Estimates are used in international and national recommendations and policies to reduce work-related hazards. |
URL | https://pubmed.ncbi.nlm.nih.gov/29213140/ |
Description | Citation in World Health Organization Position Paper: Optimizing brain health across the life course. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our studies provided new evidence on the role of heavy alcohol consumption, lack of cognitive stimulation and sleep deficits as risk factors for Alzheimer's disease and other dementias. |
URL | https://www.who.int/publications/i/item/9789240054561 |
Description | Citation in World Health Organization Position Paper: Optimizing brain health across the life course. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our studies provided new evidence on the role of heavy alcohol consumption, lack of cognitive stimulation and sleep deficits as risk factors for Alzheimer's disease and other dementias. |
URL | https://www.who.int/publications/i/item/9789240054561 |
Description | Citation in World Health Organization Position Paper: Optimizing brain health across the life course. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our studies provided new evidence on the role of heavy alcohol consumption, lack of cognitive stimulation and sleep deficits as risk factors for Alzheimer's disease and other dementias. |
URL | https://www.who.int/publications/i/item/9789240054561 |
Description | Citation in World Health Organization Position Paper: Optimizing brain health across the life course. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our studies provided new evidence on the role of heavy alcohol consumption, lack of cognitive stimulation and sleep deficits as risk factors for Alzheimer's disease and other dementias. |
URL | https://www.who.int/publications/i/item/9789240054561 |
Description | Citation in World Health Organization Position Paper: Optimizing brain health across the life course. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our studies provided new evidence on the role of heavy alcohol consumption, lack of cognitive stimulation and sleep deficits as risk factors for Alzheimer's disease and other dementias. |
URL | https://www.who.int/publications/i/item/9789240054561 |
Description | Citation in World Health Organization Position Paper: Optimizing brain health across the life course. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our studies provided new evidence on the role of heavy alcohol consumption, lack of cognitive stimulation and sleep deficits as risk factors for Alzheimer's disease and other dementias. |
URL | https://www.who.int/publications/i/item/9789240054561 |
Description | Citations in The Lancet Commission on Dementia: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our individual-level meta-analyses of up to 1.3 million people and data from 2- to 3-decade follow-up of UK men and women are used as key evidence to justify recommendations to maintain normal weight, keep systolic blood pressure below 130mmHg and avoid consuming alcohol more than 21 units per week in midlife to prevent old-age dementia, a disease for which there is no disease-modifying medication. The estimated reduction of dementia attributable to the elimination of these risk factors is 3.4%. |
URL | https://pubmed.ncbi.nlm.nih.gov/29169013/ |
Description | Citations in The Lancet Commission on Dementia: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our individual-level meta-analyses of up to 1.3 million people and data from 2- to 3-decade follow-up of UK men and women are used as key evidence to justify recommendations to maintain normal weight, keep systolic blood pressure below 130mmHg and avoid consuming alcohol more than 21 units per week in midlife to prevent old-age dementia, a disease for which there is no disease-modifying medication. The estimated reduction of dementia attributable to the elimination of these risk factors is 3.4%. |
URL | https://pubmed.ncbi.nlm.nih.gov/28588063/ |
Description | Citations in The Lancet Commission on Dementia: Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our individual-level meta-analyses of up to 1.3 million people and data from 2- to 3-decade follow-up of UK men and women are used as key evidence to justify recommendations to maintain normal weight, keep systolic blood pressure below 130mmHg and avoid consuming alcohol more than 21 units per week in midlife to prevent old-age dementia, a disease for which there is no disease-modifying medication. The estimated reduction of dementia attributable to the elimination of these risk factors is 3.4%. |
URL | https://pubmed.ncbi.nlm.nih.gov/28514478/ |
Description | Heart Disease and Stroke Statistics-Update (2023) A Report from the American Heart Association. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Our evidence demonstrates the importance of targeting occupational and lifestyle factors in order to prevent cardiovascular disease and delay progression of these diseases. |
URL | https://www.ahajournals.org/doi/10.1161/CIR.0000000000001123?url_ver=Z39.88-2003&rfr_id=ori:rid:cros... |
Description | WHO European Regional Obesity Report |
Geographic Reach | Europe |
Policy Influence Type | Citation in other policy documents |
Impact | Our analyses of data across multiple continents demonstrate the important role of social determinants of health, including metabolic health. |
URL | https://apps.who.int/iris/bitstream/handle/10665/353747/9789289057738-eng.pdf |
Description | World Health Organization Position Paper: Optimizing brain health across the life course. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Participation in a guidance/advisory committee |
Impact | Increased attention to the harmful effects of heavy alcohol use, lack of cognitive stimulation and insuffient sleep on brain health. |
Description | World Heart Federation and World Obesity Federation joint position paper on obesity and cardiovascular disease |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | We provided evidence on the impact of obesity on multimorbidity and cascades of diseases. |
URL | https://pubmed.ncbi.nlm.nih.gov/36007112/ |
Description | Academy of Finland, Finland (350426) |
Amount | € 500,000 (EUR) |
Funding ID | 350426 |
Organisation | Academy of Finland |
Sector | Public |
Country | Finland |
Start | 08/2022 |
End | 08/2026 |
Description | COVID-19 and Alzheimer's disease & related dementias: a longitudinal approach |
Amount | $499,136 (USD) |
Funding ID | 3R01AG056477-03S1 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start |
Description | Collaborative Award in Science |
Amount | £4,000,200 (GBP) |
Funding ID | 221854/Z/20/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 02/2021 |
End | 01/2026 |
Description | ERC Consolidator grant: LS7 - Prevention, Diagnosis & Treatment of Human Diseases |
Amount | € 2,000,000 (EUR) |
Organisation | European Research Council (ERC) |
Sector | Public |
Country | Belgium |
Start | 04/2023 |
End | 04/2028 |
Description | ERC-2021-CoG. Circadian rhythm: from preclinical to post-diagnosis dementia |
Amount | € 2,000,000 (EUR) |
Organisation | European Research Council (ERC) |
Sector | Public |
Country | Belgium |
Start | 04/2023 |
End | 04/2028 |
Description | Integrated research on prevention, treatment and care for dementia - formulation of OU-UCL international joint research centre |
Amount | ¥60,000,000 (JPY) |
Organisation | Osaka University |
Sector | Academic/University |
Country | Japan |
Start | 08/2019 |
End | 03/2022 |
Description | National Institute on Aging (NIH), US (R01AG062553) |
Amount | $1,500,000 (USD) |
Funding ID | R01AG062553 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 07/2019 |
End | 05/2024 |
Description | The Whitehall II study: A core resource for ageing research |
Amount | £499,999 (GBP) |
Funding ID | MR/Y014154/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2024 |
End | 02/2027 |
Description | UCL / Wellcome Trust Institutional Strategic Support Fund (ISSF3) |
Amount | £28,548 (GBP) |
Funding ID | 204841/Z/16/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 04/2020 |
End | 10/2020 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | Imperial College London |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | This consortium aims to bring together leading researchers and proteomics data from multiple neurodegeneration (ND) cohorts and build the largest ND proteomics dataset to date for optimal biomarker and disease mechanism discovery. This consortium will accelerate upstream proteomics studies for ADRD's by bringing together data from healthy controls and AD, PD, ALS, and other dementias such as FTD to identify unique and shared characteristics. The ADRD Proteomics Consortium will achieve this goal by providing a secure cloud-based data sharing platform for consortium member collaboration and data storage. |
Collaborator Contribution | There are over 20 other cohort studies which also participate in the Consortium. The consortium is also supported Gates Ventures. |
Impact | Harmonisation of datasets have already started. The aim is to generate a safe research portal for scientists to allow analysis of the largest pooled dataset on proteomics and the risk and prognosis of neurodegenerative diseases. This unique dataset will provide a valuable resource for identifying new drug targets and novel diagnostic markers |
Start Year | 2024 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | Imperial College London |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | We provide data to the super-dataset. In addition, we are members of the Consortium Steering Group and the Data Analysis Group. The aim of the consortium is to create the world's largest Neurodegen proteomics dataset by harrmonising and pooling studies in Europe and the US. In addition to Whitehall II, participating studies to date include the atherosclerosis Risk in Communities (ARIC) study (NIA, Johns Hopkins), the DOminantly Inherited alxheimer Network (DIAN) study (Washington University), the CHARIOT-PRO study (Imperial College and several studies on clinical patients. Industry partners include SomaLogic, Jansen and Johnson&Johnson. |
Collaborator Contribution | Partners provide expertise, steering, data, analysts, help in data harmonisaton. |
Impact | We are still harmonising datasets. |
Start Year | 2022 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | Janssen Research & Development |
Country | Global |
Sector | Private |
PI Contribution | This consortium aims to bring together leading researchers and proteomics data from multiple neurodegeneration (ND) cohorts and build the largest ND proteomics dataset to date for optimal biomarker and disease mechanism discovery. This consortium will accelerate upstream proteomics studies for ADRD's by bringing together data from healthy controls and AD, PD, ALS, and other dementias such as FTD to identify unique and shared characteristics. The ADRD Proteomics Consortium will achieve this goal by providing a secure cloud-based data sharing platform for consortium member collaboration and data storage. |
Collaborator Contribution | There are over 20 other cohort studies which also participate in the Consortium. The consortium is also supported Gates Ventures. |
Impact | Harmonisation of datasets have already started. The aim is to generate a safe research portal for scientists to allow analysis of the largest pooled dataset on proteomics and the risk and prognosis of neurodegenerative diseases. This unique dataset will provide a valuable resource for identifying new drug targets and novel diagnostic markers |
Start Year | 2024 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | Johns Hopkins University |
Department | John Hopkins Malaria Research Institute |
Country | United States |
Sector | Academic/University |
PI Contribution | We provide data to the super-dataset. In addition, we are members of the Consortium Steering Group and the Data Analysis Group. The aim of the consortium is to create the world's largest Neurodegen proteomics dataset by harrmonising and pooling studies in Europe and the US. In addition to Whitehall II, participating studies to date include the atherosclerosis Risk in Communities (ARIC) study (NIA, Johns Hopkins), the DOminantly Inherited alxheimer Network (DIAN) study (Washington University), the CHARIOT-PRO study (Imperial College and several studies on clinical patients. Industry partners include SomaLogic, Jansen and Johnson&Johnson. |
Collaborator Contribution | Partners provide expertise, steering, data, analysts, help in data harmonisaton. |
Impact | We are still harmonising datasets. |
Start Year | 2022 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | Johns Hopkins University |
Department | School of Medicine Johns Hopkins |
Country | United States |
Sector | Academic/University |
PI Contribution | This consortium aims to bring together leading researchers and proteomics data from multiple neurodegeneration (ND) cohorts and build the largest ND proteomics dataset to date for optimal biomarker and disease mechanism discovery. This consortium will accelerate upstream proteomics studies for ADRD's by bringing together data from healthy controls and AD, PD, ALS, and other dementias such as FTD to identify unique and shared characteristics. The ADRD Proteomics Consortium will achieve this goal by providing a secure cloud-based data sharing platform for consortium member collaboration and data storage. |
Collaborator Contribution | There are over 20 other cohort studies which also participate in the Consortium. The consortium is also supported Gates Ventures. |
Impact | Harmonisation of datasets have already started. The aim is to generate a safe research portal for scientists to allow analysis of the largest pooled dataset on proteomics and the risk and prognosis of neurodegenerative diseases. This unique dataset will provide a valuable resource for identifying new drug targets and novel diagnostic markers |
Start Year | 2024 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | Johnson & Johnson |
Country | United States |
Sector | Private |
PI Contribution | We provide data to the super-dataset. In addition, we are members of the Consortium Steering Group and the Data Analysis Group. The aim of the consortium is to create the world's largest Neurodegen proteomics dataset by harrmonising and pooling studies in Europe and the US. In addition to Whitehall II, participating studies to date include the atherosclerosis Risk in Communities (ARIC) study (NIA, Johns Hopkins), the DOminantly Inherited alxheimer Network (DIAN) study (Washington University), the CHARIOT-PRO study (Imperial College and several studies on clinical patients. Industry partners include SomaLogic, Jansen and Johnson&Johnson. |
Collaborator Contribution | Partners provide expertise, steering, data, analysts, help in data harmonisaton. |
Impact | We are still harmonising datasets. |
Start Year | 2022 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | Maastricht University (UM) |
Country | Netherlands |
Sector | Academic/University |
PI Contribution | This consortium aims to bring together leading researchers and proteomics data from multiple neurodegeneration (ND) cohorts and build the largest ND proteomics dataset to date for optimal biomarker and disease mechanism discovery. This consortium will accelerate upstream proteomics studies for ADRD's by bringing together data from healthy controls and AD, PD, ALS, and other dementias such as FTD to identify unique and shared characteristics. The ADRD Proteomics Consortium will achieve this goal by providing a secure cloud-based data sharing platform for consortium member collaboration and data storage. |
Collaborator Contribution | There are over 20 other cohort studies which also participate in the Consortium. The consortium is also supported Gates Ventures. |
Impact | Harmonisation of datasets have already started. The aim is to generate a safe research portal for scientists to allow analysis of the largest pooled dataset on proteomics and the risk and prognosis of neurodegenerative diseases. This unique dataset will provide a valuable resource for identifying new drug targets and novel diagnostic markers |
Start Year | 2024 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | National Institutes of Health (NIH) |
Department | National Institute on Aging |
Country | United States |
Sector | Public |
PI Contribution | This consortium aims to bring together leading researchers and proteomics data from multiple neurodegeneration (ND) cohorts and build the largest ND proteomics dataset to date for optimal biomarker and disease mechanism discovery. This consortium will accelerate upstream proteomics studies for ADRD's by bringing together data from healthy controls and AD, PD, ALS, and other dementias such as FTD to identify unique and shared characteristics. The ADRD Proteomics Consortium will achieve this goal by providing a secure cloud-based data sharing platform for consortium member collaboration and data storage. |
Collaborator Contribution | There are over 20 other cohort studies which also participate in the Consortium. The consortium is also supported Gates Ventures. |
Impact | Harmonisation of datasets have already started. The aim is to generate a safe research portal for scientists to allow analysis of the largest pooled dataset on proteomics and the risk and prognosis of neurodegenerative diseases. This unique dataset will provide a valuable resource for identifying new drug targets and novel diagnostic markers |
Start Year | 2024 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | SomaLogic |
Country | United States |
Sector | Private |
PI Contribution | This consortium aims to bring together leading researchers and proteomics data from multiple neurodegeneration (ND) cohorts and build the largest ND proteomics dataset to date for optimal biomarker and disease mechanism discovery. This consortium will accelerate upstream proteomics studies for ADRD's by bringing together data from healthy controls and AD, PD, ALS, and other dementias such as FTD to identify unique and shared characteristics. The ADRD Proteomics Consortium will achieve this goal by providing a secure cloud-based data sharing platform for consortium member collaboration and data storage. |
Collaborator Contribution | There are over 20 other cohort studies which also participate in the Consortium. The consortium is also supported Gates Ventures. |
Impact | Harmonisation of datasets have already started. The aim is to generate a safe research portal for scientists to allow analysis of the largest pooled dataset on proteomics and the risk and prognosis of neurodegenerative diseases. This unique dataset will provide a valuable resource for identifying new drug targets and novel diagnostic markers |
Start Year | 2024 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | SomaLogic |
Country | United States |
Sector | Private |
PI Contribution | We provide data to the super-dataset. In addition, we are members of the Consortium Steering Group and the Data Analysis Group. The aim of the consortium is to create the world's largest Neurodegen proteomics dataset by harrmonising and pooling studies in Europe and the US. In addition to Whitehall II, participating studies to date include the atherosclerosis Risk in Communities (ARIC) study (NIA, Johns Hopkins), the DOminantly Inherited alxheimer Network (DIAN) study (Washington University), the CHARIOT-PRO study (Imperial College and several studies on clinical patients. Industry partners include SomaLogic, Jansen and Johnson&Johnson. |
Collaborator Contribution | Partners provide expertise, steering, data, analysts, help in data harmonisaton. |
Impact | We are still harmonising datasets. |
Start Year | 2022 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | University Hospital Tuebingen |
Country | Germany |
Sector | Academic/University |
PI Contribution | This consortium aims to bring together leading researchers and proteomics data from multiple neurodegeneration (ND) cohorts and build the largest ND proteomics dataset to date for optimal biomarker and disease mechanism discovery. This consortium will accelerate upstream proteomics studies for ADRD's by bringing together data from healthy controls and AD, PD, ALS, and other dementias such as FTD to identify unique and shared characteristics. The ADRD Proteomics Consortium will achieve this goal by providing a secure cloud-based data sharing platform for consortium member collaboration and data storage. |
Collaborator Contribution | There are over 20 other cohort studies which also participate in the Consortium. The consortium is also supported Gates Ventures. |
Impact | Harmonisation of datasets have already started. The aim is to generate a safe research portal for scientists to allow analysis of the largest pooled dataset on proteomics and the risk and prognosis of neurodegenerative diseases. This unique dataset will provide a valuable resource for identifying new drug targets and novel diagnostic markers |
Start Year | 2024 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | University of Glasgow |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | This consortium aims to bring together leading researchers and proteomics data from multiple neurodegeneration (ND) cohorts and build the largest ND proteomics dataset to date for optimal biomarker and disease mechanism discovery. This consortium will accelerate upstream proteomics studies for ADRD's by bringing together data from healthy controls and AD, PD, ALS, and other dementias such as FTD to identify unique and shared characteristics. The ADRD Proteomics Consortium will achieve this goal by providing a secure cloud-based data sharing platform for consortium member collaboration and data storage. |
Collaborator Contribution | There are over 20 other cohort studies which also participate in the Consortium. The consortium is also supported Gates Ventures. |
Impact | Harmonisation of datasets have already started. The aim is to generate a safe research portal for scientists to allow analysis of the largest pooled dataset on proteomics and the risk and prognosis of neurodegenerative diseases. This unique dataset will provide a valuable resource for identifying new drug targets and novel diagnostic markers |
Start Year | 2024 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | University of Oxford |
Country | United Kingdom |
Sector | Academic/University |
PI Contribution | This consortium aims to bring together leading researchers and proteomics data from multiple neurodegeneration (ND) cohorts and build the largest ND proteomics dataset to date for optimal biomarker and disease mechanism discovery. This consortium will accelerate upstream proteomics studies for ADRD's by bringing together data from healthy controls and AD, PD, ALS, and other dementias such as FTD to identify unique and shared characteristics. The ADRD Proteomics Consortium will achieve this goal by providing a secure cloud-based data sharing platform for consortium member collaboration and data storage. |
Collaborator Contribution | There are over 20 other cohort studies which also participate in the Consortium. The consortium is also supported Gates Ventures. |
Impact | Harmonisation of datasets have already started. The aim is to generate a safe research portal for scientists to allow analysis of the largest pooled dataset on proteomics and the risk and prognosis of neurodegenerative diseases. This unique dataset will provide a valuable resource for identifying new drug targets and novel diagnostic markers |
Start Year | 2024 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | VU University Medical Center |
Country | Netherlands |
Sector | Academic/University |
PI Contribution | This consortium aims to bring together leading researchers and proteomics data from multiple neurodegeneration (ND) cohorts and build the largest ND proteomics dataset to date for optimal biomarker and disease mechanism discovery. This consortium will accelerate upstream proteomics studies for ADRD's by bringing together data from healthy controls and AD, PD, ALS, and other dementias such as FTD to identify unique and shared characteristics. The ADRD Proteomics Consortium will achieve this goal by providing a secure cloud-based data sharing platform for consortium member collaboration and data storage. |
Collaborator Contribution | There are over 20 other cohort studies which also participate in the Consortium. The consortium is also supported Gates Ventures. |
Impact | Harmonisation of datasets have already started. The aim is to generate a safe research portal for scientists to allow analysis of the largest pooled dataset on proteomics and the risk and prognosis of neurodegenerative diseases. This unique dataset will provide a valuable resource for identifying new drug targets and novel diagnostic markers |
Start Year | 2024 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | Washington University School of Medicine |
Country | United States |
Sector | Academic/University |
PI Contribution | This consortium aims to bring together leading researchers and proteomics data from multiple neurodegeneration (ND) cohorts and build the largest ND proteomics dataset to date for optimal biomarker and disease mechanism discovery. This consortium will accelerate upstream proteomics studies for ADRD's by bringing together data from healthy controls and AD, PD, ALS, and other dementias such as FTD to identify unique and shared characteristics. The ADRD Proteomics Consortium will achieve this goal by providing a secure cloud-based data sharing platform for consortium member collaboration and data storage. |
Collaborator Contribution | There are over 20 other cohort studies which also participate in the Consortium. The consortium is also supported Gates Ventures. |
Impact | Harmonisation of datasets have already started. The aim is to generate a safe research portal for scientists to allow analysis of the largest pooled dataset on proteomics and the risk and prognosis of neurodegenerative diseases. This unique dataset will provide a valuable resource for identifying new drug targets and novel diagnostic markers |
Start Year | 2024 |
Description | The Alzheimer's Disease and Related Dementias (ADRD) Proteomics Consortium |
Organisation | Washington University in St Louis |
Department | School of Medicine |
Country | United States |
Sector | Academic/University |
PI Contribution | We provide data to the super-dataset. In addition, we are members of the Consortium Steering Group and the Data Analysis Group. The aim of the consortium is to create the world's largest Neurodegen proteomics dataset by harrmonising and pooling studies in Europe and the US. In addition to Whitehall II, participating studies to date include the atherosclerosis Risk in Communities (ARIC) study (NIA, Johns Hopkins), the DOminantly Inherited alxheimer Network (DIAN) study (Washington University), the CHARIOT-PRO study (Imperial College and several studies on clinical patients. Industry partners include SomaLogic, Jansen and Johnson&Johnson. |
Collaborator Contribution | Partners provide expertise, steering, data, analysts, help in data harmonisaton. |
Impact | We are still harmonising datasets. |
Start Year | 2022 |
Description | 2023-2024: Commissioner, Lancet 2024 Commission on Dementia Prevention, Intervention and Care |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | The review will be published in July 2024, affecting prevention guidelines internationally. |
Year(s) Of Engagement Activity | 2023 |
Description | Association of non-diabetic hyperglycaemia and microvascular and macrovascular complications of type 2 diabetes: a retrospective cohort study. 55th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Barcelona, SPAIN. Adam Tabak |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Presentation sparking questions and discussion. |
Year(s) Of Engagement Activity | 2019 |
Description | Association of sleep duration at age 50, 60 and 70 with incidence of dementia at AAIC (Alzheimer Association international conference), 26 to 30th of July |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Association of sleep duration at age 50, 60 and 70 with incidence of dementia at AAIC (Alzheimer Association international conference), 26 to 30th of July |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.alz.org/aaic/highlights2021.asp |
Description | BMJ Opinion Blog: Séverine Sabia and Archana Singh-Manoux: The implications of cardiovascular health for dementia. |
Form Of Engagement Activity | Engagement focused website, blog or social media channel |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Media coverage ensuring that study results were available to a wider audience, including the general public and resulting in increased interest in the study. |
Year(s) Of Engagement Activity | 2019 |
URL | https://blogs.bmj.com/bmj/2019/08/07/severine-sabia-archana-singh-manoux-the-implications-of-cardiov... |
Description | College of experts, Neurosciences, cognitives sciences, neurology, psychiatry Institute, France |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Policymakers/politicians |
Results and Impact | Policy and governance of research |
Year(s) Of Engagement Activity | 2020 |
URL | https://aviesan.fr/aviesan/accueil/menu-header/instituts-thematiques-multi-organismes/neurosciences-... |
Description | Conference presentation: 'Integrated central blood pressure-aortic stiffness risk categories and cardiovascular mortality in end-stage renal disease' 29th European Meeting of Hypertension and Cardiovascular Protection of the European-Society-of-Hypertension (ESH), Milan. Adam Tabak. |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Presentation: 'Integrated central blood pressure-aortic stiffness risk categories and cardiovascular mortality in end-stage renal disease'. 29th European Meeting of Hypertension and Cardiovascular Protection of the European-Society-of-Hypertension (ESH), Milan, ITALY, JUN 21-24, 2019. Research findings presented sparking questions and discussion. |
Year(s) Of Engagement Activity | 2019 |
Description | Diabetes in Pregnancy Guideline Development Panel (GDP) of the Endocrine Society (European Association for the Study of Diabetes [EASD] representative) |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | The GDP started its activities in 2022. It is expected to reach an evidence-based guideline for the care of pregestational diabetes by the end of 2025 that will be published in the Journal of Clinical Endocrinology and Metabolism. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.endocrine.org/clinical-practice-guidelines/guidelines-in-development |
Description | Editorial Advisory Board, The Lancet Regional Health Europe. Prof Archana Singh-Manoux |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Editorial work. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.thelancet.com/lanepe/international-advisory-board |
Description | Editorial: BMJ Editorial The determinants of cognitive decline and dementia. BMJ 2019;366:l4946 |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | BMJ editorial regarding two linked Whitehall II research papers. The editorial recognised the 'tremendous power of the Whitehall study' increasing the reputation of the study. |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.bmj.com/content/366/bmj.l4946 |
Description | European member, US National Cross-sector Agenda for Occupational Safety and Health Research and Practice - the Cancer, Reproductive, Cardiovascular, and Other Chronic Disease Prevention Program |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Advisor and expert in work-related risk factors. Prof. Mika Kivimaki |
Year(s) Of Engagement Activity | 2022 |
Description | European member, US National Cross-sector Agenda for Occupational Safety and Health Research and Practice - the Cancer, Reproductive, Cardiovascular, and Other Chronic Disease Prevention Program 2017-2027 |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Advisor & expert in work-related risk factors. Prof. Mika Kivimaki |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.cdc.gov/nora/councils/crc/councilmembers.html |
Description | Expert in Scientific committee: Santé Publique France (Public Health France agency) |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Policymakers/politicians |
Results and Impact | Prof Severine is part of a scientific committee to help the organisation to find research strategies and priorities. |
Year(s) Of Engagement Activity | 2023 |
Description | Frank P. Oral presentaton: Excess risk of hospitalisaton for physical disease in people with depression. In American Psychosomatic Society Conference: Challenging the Future: Towards a Better Biopsychosocial Health. San Juan, Puerto rico, 8-11 March 2023 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | This was an oral presentation in a large international scientific conference |
Year(s) Of Engagement Activity | 2023 |
URL | https://psychosomatic.org/wp-content/uploads/2022/03/APS-2022-Annual-Meeting-Abstracts.pdf |
Description | GLAD Force Diet and Nutrition using GBD data |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Professional Practitioners |
Results and Impact | Participation in workshop. |
Year(s) Of Engagement Activity | 2022 |
Description | GOOD France healthy diet for healthy planet conference (Lyon, France). |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Professional Practitioners |
Results and Impact | Debate at GOOD France healthy diet for healthy planet conference. |
Year(s) Of Engagement Activity | 2022 |
Description | International Workshop: A focus on statistical methods to analyse accelerometer-measured physical activity |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Attendance at a workshop learning about statistical methods to analyse accelerometer-measured physical activity giving the opportunity to liaise with top experts from different countries in the approaches to analyse physical activity data. |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.granadacongresos.com/aiw2019 |
Description | Interview with Medpage Today about 'Association between socioeconomic status and the development of mental and physical health conditions in adulthood: a multi-cohort study' |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Interviewed by Medpage Today about 'Association between socioeconomic status and the development of mental and physical health conditions in adulthood: a multi-cohort study. Kivimaki et al. Lancet Public Health. 2020 Mar;5(3):e140-e149. 'Cascade' of Disease ID'd in Poorer Socioeconomic Groups - Later development of physical diseases tied to mental, behavioral disorders' February 5, 2020. High level of media coverage ensuring that study results were available to a wider audience, including the general public |
Year(s) Of Engagement Activity | 2020 |
URL | https://www.medpagetoday.com/psychiatry/generalpsychiatry/84723 |
Description | Invited expert member of the MRC Ageing Research Steering Group Meeting |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Professional Practitioners |
Results and Impact | Invited expert to advisory body |
Year(s) Of Engagement Activity | 2022 |
Description | Invited speech: Treating patients with type 1 diabetes from adolescence to senility - workshop. Adam Tabak |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Postgraduate students |
Results and Impact | Invited speech at workshop for post grad students generating interest in study data. |
Year(s) Of Engagement Activity | 2019 |
Description | Kivimaki M. Keynote: Disease prevention in non-communicable diseases and mental disorders. In Nordic Pharmacoepidemiology Conference: Data-driven decision making in healthcare and health promotion. Tampere, Finland, 16-18 November 2022 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Keynote Presentation: Disease prevention in non-communicable diseases and mental disorders. In Nordic Pharmacoepidemiology Conference: Data-driven decision making in healthcare and health promotion. Tampere, Finland, 16-18 November 2022 |
Year(s) Of Engagement Activity | 2022 |
URL | https://events.tuni.fi/norpen2022/programme/ |
Description | Media coverage for 'Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies' Kivimaki et al. Inews: Dementia article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://inews.co.uk/news/science/dementia-working-doctor-company-boss-better-protection-bus-driver-f... |
Description | Media Interview: Ces loisirs seraient ceux qui protègent le plus contre la démence. Sciences et vie (comments on findings from other researchers on the role of social activities on cognitive ageing) |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Prof Severine was asked to comment on findings from other researchers on the role of social activities on cognitive ageing. Readers will be aware on the importance of various types of activities for their cognitive health. |
Year(s) Of Engagement Activity | 2023 |
Description | Media Interview: Le vieillissement, dans la ligne de mire de la recherche. Magazine de l'Inserm. (interview was about results on findings on our study that showed that short sleep is associated with higher risk of multimorbidity) Severine |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Prof Severine Interviewed about results on findings on our study that showed that short sleep is associated with higher risk of multimorbidity. Readers should be aware of the risk and some might talk to their GP if they have sleep problems. |
Year(s) Of Engagement Activity | 2023 |
Description | Media Interview: Sommeil réduit et risque de multimorbidité: un lien étroit étable. Avenir et Santé. (Interview about results on findings on our study that showed that short sleep is associated with higher risk of multimorbidity) Severine |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Interview about about results on findings on our study that showed that short sleep is associated with higher risk of multimorbidity. Readers should be aware of the risk and some might talk to their GP if they have sleep problems. |
Year(s) Of Engagement Activity | 2023 |
Description | Media attention for 'Severe Infection and Risk of Cardiovascular Disease: A Multicohort Study'. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | NEJM Journal Watch: Patients Hospitalized for Severe Infection Have Subsequent Excess Risk for Cardiovascular Events. This brought attention to the study and increased requests for further information. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.jwatch.org/na56007/2023/04/18/patients-hospitalized-severe-infection-have-subsequent |
Description | Media attention for 'Severe Infection and Risk of Cardiovascular Disease: A Multicohort Study'. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | TCT MD article: Severe Infections Linked to a Variety of CV Events, Both Acute and Long-term. This brought attention to the study and increased requests for further information. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.tctmd.com/news/severe-infections-linked-variety-cv-events-both-acute-and-long-term |
Description | Media coverage for '5-year versus risk-category-specific screening intervals for cardiovascular disease prevention: a cohort study' BBC article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Interviewed for BBC News article 'Targeted checks 'prevent one-in-10 heart attacks' regarding '5-year versus risk-category-specific screening intervals for cardiovascular disease prevention: a cohort study' Lancet Public Health. 2019;4(4):e189-e199. Widespread media coverage which increased awareness of the study. |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.bbc.co.uk/news/health-47981644 |
Description | Media coverage for '5-year versus risk-category-specific screening intervals for cardiovascular disease prevention: a cohort study' Docwire article 'Individualizing the Screening Interval for High-risk CVD Patients,. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Report and interviewed for Docwire. High level of media coverage ensuring that study results were available to a wider audience, including the general public. |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.docwirenews.com/docwire-pick/cardiology-picks/screening-interval-cvd-patients/ |
Description | Media coverage for '5-year versus risk-category-specific screening intervals for cardiovascular disease prevention: a cohort study'. Telegraph. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Extensive media coverage for '5-year versus risk-category-specific screening intervals for cardiovascular disease prevention: a cohort study'. High level of media coverage ensuring that study results were available to a wider audience, including the general public. |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.telegraph.co.uk/news/2019/04/20/almost-one-ten-heart-attacks-strokes-could-prevented-hig... |
Description | Media coverage for '5-year versus risk-category-specific screening intervals for cardiovascular disease prevention: a cohort study'. The USA Times report and interview. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Report and interview in The USA Times 'Focused checks forestall one in 10 coronary heart assaults'. High level of media coverage ensuring that study results were available to a wider audience, including the general public. |
Year(s) Of Engagement Activity | 2019 |
URL | https://theusatimes.net/lifestyle/health/focused-checks-forestall-one-in-10-coronary-heart-assaults/ |
Description | Media coverage for '5-year versus risk-category-specific screening intervals for cardiovascular disease prevention: a cohort study'. US news report and interview. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Report and interview in The US News 'Work Stress, Poor Sleep, High Blood Pressure a Deadly Trio'. High level of media coverage ensuring that study results were available to a wider audience, including the general public. |
Year(s) Of Engagement Activity | 2019 |
URL | https://theusatimes.net/lifestyle/health/focused-checks-forestall-one-in-10-coronary-heart-assaults/ |
Description | Media coverage for 'Association between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study' Hessen et al. Express article. article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.express.co.uk/life-style/health/1560225/dementia-risk-multimorbidity |
Description | Media coverage for 'Association between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study' Hessen et al. Guardian article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.theguardian.com/society/2022/feb/02/two-chronic-health-problems-middle-age-double-dement... |
Description | Media coverage for 'Association between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study' Hessen et al. Medical News Today article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.medicalnewstoday.com/articles/dementia-midlife-chronic-conditions-linked-to-increased-ri... |
Description | Media coverage for 'Association between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study' Hessen et al. Telegraph article. article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.telegraph.co.uk/news/2022/02/03/high-blood-pressure-diabetes-middle-age-could-double-dem... |
Description | Media coverage for 'Association between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study' Hessen et al. The Irish Times article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.irishtimes.com/life-and-style/health-family/dementia-risk-doubles-with-two-or-more-chron... |
Description | Media coverage for 'Association between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study' Hessen et al. The Sun article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.thesun.co.uk/health/17529829/two-common-conditions-increase-dementia-risk/ |
Description | Media coverage for 'Association between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study' Hessen et al. Times article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.thetimes.co.uk/article/dementia-twice-as-likely-with-two-chronic-illnesses-txkvf7t7f |
Description | Media coverage for 'Association between age at onset of multimorbidity and incidence of dementia: 30 year follow-up in Whitehall II prospective cohort study' Hessen et al. Yahoo Life article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.yahoo.com/lifestyle/experts-key-indicator-dementia-risk-144532983.html?guccounter=1&guce... |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. Daily Express news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.express.co.uk/life-style/health/1333720/Dementia-warning-drinking-alcohol-university-coll... |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. Daily Mail news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.dailymail.co.uk/health/article-8714025/Passing-drunk-DOUBLE-risk-later-developing-dementi... |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. Daily Telegraph news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.dailytelegraph.com.au/technology/science/getting-blind-drunk-may-double-your-risk-of-deve... |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. DrugFree.org news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Patients, carers and/or patient groups |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://drugfree.org/drug-and-alcohol-news/passing-out-after-drinking-linked-to-increased-risk-of-dem... |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. InterestingEngineering.com article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | https://interestingengineering.com/large-study-reveals-excessive-drinking-doubles-the-risk-of-dement... |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. Science Alert news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | https://www.sciencealert.com/drinking-until-you-pass-out-linked-to-doubled-risk-of-dementia-giant-st... |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. Science times news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.sciencetimes.com/articles/27248/20200910/passing-out-drunk-double-risks-dementia-includin... |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. The Irish Sun news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.thesun.ie/news/5887647/passing-out-drunk-could-double-risk-dementia/ |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. The News Pocket article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://thenewspocket.com/passing-drunk-out-might-double-check-your-dementia-risk |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. Trendwide.com news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. United Press International news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.upi.com/Health_News/2020/09/09/Drinking-to-the-point-of-passing-out-increases-dementia-ri... |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. Weekly Times Now news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.weeklytimesnow.com.au/breaking-news/getting-blind-drunk-may-double-your-risk-of-developin... |
Description | Media coverage for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. Worldnewj.com news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
Description | Media coverage for 'Association of healthy lifestyle with years lived free of major chronic diseases: A prospective multicohort study'. Daily Mail news article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.dailymail.co.uk/sciencetech/article-8200241/Sticking-three-good-habits-add-10-years-disea... |
Description | Media coverage for 'Association of healthy lifestyle with years lived free of major chronic diseases: A prospective multicohort study'. TCTMD news article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.tctmd.com/news/adherence-healthy-habits-linked-years-free-chronic-disease |
Description | Media coverage for 'Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study. Times article 'Good heart health in middle age may lower your risk of dementia'. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage ensuring study results were available to a wider audience, including the general public. Further interest generated in the study. |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.thetimes.co.uk/article/good-heart-health-in-middle-age-may-lower-your-risk-of-dementia-p... |
Description | Media coverage for 'Association of ideal cardiovascular health at age 50 with incidence of dementia: 25 year follow-up of Whitehall II cohort study. • ITV News 'Good heart health in middle age linked to lower dementia risk - study' |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage ensuring study results were available to a wider audience, including the general public. Further interest generated in the study. |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.itv.com/news/2019-08-07/good-heart-health-in-middle-age-linked-to-lower-dementia-risk-st... |
Description | Media coverage for 'Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II cohort study. ABC News |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Science Daily new item: Adults sleeping five hours or less a night have increased risk of chronic illnesses, study finds. This brought attention to the study and increased requests for further information. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.abc.net.au/news/health/2022-10-19/sleep-duration-linked-with-chronic-illness-study-finds... |
Description | Media coverage for 'Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II cohort study. CNN News |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | CNN News article: People who sleep 5 hours or less a night face higher risk of multiple health problems as they age, study finds. This media brought attention to the study and increased requests for information. |
Year(s) Of Engagement Activity | 2022 |
URL | https://edition.cnn.com/2022/10/18/health/short-sleep-multiple-chronic-diseases-wellness/index.html |
Description | Media coverage for 'Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II cohort study. Daily Express |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Daily Express article: Five hours' sleep could set the stage for 'multiple diseases', warns major new study. This brought attention to the study and increased requests for further information. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.express.co.uk/life-style/health/1685033/how-to-live-longer-sleeping-less-than-five-hours |
Description | Media coverage for 'Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II cohort study. Daily Mail |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | Daily Mail article: Getting less than five hours of sleep a night can DOUBLE your risk of developing dementia, study warns. Media brought further attention and increased requests for information. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.dailymail.co.uk/sciencetech/article-9253509/Less-five-hours-sleep-night-double-dementia-... |
Description | Media coverage for 'Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II cohort study. Science Daily |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Science Daily article: Less than five hours' sleep a night linked to higher risk of multiple diseases. This brought attention to the study and increased requests for further information. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.sciencedaily.com/releases/2022/10/221018220538.htm |
Description | Media coverage for 'Association of sleep duration in middle and old age with incidence of dementia' Sabia S et al |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Press release: Lack of sleep in middle age linked to dementia risk: High level of media coverage generting further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.ucl.ac.uk/news/2021/apr/lack-sleep-middle-age-linked-dementia-risk |
Description | Media coverage for 'Association of sleep duration in middle and old age with incidence of dementia' Sabia S et al UCL Press Release |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Press release: Lack of sleep in middle age linked to dementia risk: High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.ucl.ac.uk/news/2021/apr/lack-sleep-middle-age-linked-dementia-risk |
Description | Media coverage for 'Association of sleep duration in middle and old age with incidence of dementia' Sabia S et al. CNN News |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://edition.cnn.com/2021/04/20/health/sleep-dementia-risk-study-wellness/index.html |
Description | Media coverage for 'Association of sleep duration in middle and old age with incidence of dementia' Sabia S et al. The Times 'Middle-aged who sleep six hours or less a night have higher dementia risk' |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.thetimes.co.uk/article/middle-aged-adults-sleep-dementia-risk-8phzp973b |
Description | Media coverage for 'Association of sleep duration in middle and old age with incidence of dementia' Daily Mail 'Lack of SLEEP can increase your risk of dementia: People who regularly get less than six hours per night are up to 30% more likely to develop the disease, study finds' |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.dailymail.co.uk/sciencetech/article-9491791/Lack-SLEEP-increase-risk-dementia-study-find... |
Description | Media coverage for 'Association of sleep duration in middle and old age with incidence of dementia' Sabia S, The Guardian Middle-aged people who sleep six hours or less at greater risk of dementia, study finds |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.ucl.ac.uk/news/2021/apr/lack-sleep-middle-age-linked-dementia-risk |
Description | Media coverage for 'Association of sleep duration in middle and old age with incidence of dementia' Sabia S. The Boston Globe. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.bostonglobe.com/2021/04/20/nation/sleeping-too-little-middle-age-may-increase-dementia-r... |
Description | Media coverage for 'Association of sleep duration in middle and old age with incidence of dementia' Sabia et al. New York Times |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage resulting in increased interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.nytimes.com/2021/04/20/health/sleep-dementia-risk.html |
Description | Media coverage for 'Association of sleep duration in middle and old age with incidence of dementia' Sabia et al. Science Alert. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.sciencealert.com/sleeping-less-than-6-hours-a-night-linked-to-higher-dementia-risk-scien... |
Description | Media coverage for 'Association of sleep duration in middle and old age with incidence of dementia' Sabia et al. The Irish Times |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generting further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.irishtimes.com/news/health/study-finds-higher-rate-of-dementia-in-those-who-get-less-sle... |
Description | Media coverage for 'Association of sleep duration in middle and old age with incidence of dementia' Sabia st al. The Wall Street Journal. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.wsj.com/articles/sleeping-six-hours-or-less-linked-to-higher-dementia-risk-study-finds-1... |
Description | Media coverage for 'Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study'. The Guardian article 'Health social life could ward off dementia' |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage ensuring study results were available to a wider audience, including the general public. Further interest generated in the study. |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.theguardian.com/society/2019/aug/02/healthy-social-life-could-ward-off-dementia-study-sh... |
Description | Media coverage for 'Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study'. The Independent article 'Seeing friends regularly lowers dementia risk, study suggests' |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage ensuring that study results were available to a wider audience, including the general public. Further interest in the study generated. |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.independent.co.uk/news/health/dementia-prevention-retirement-health-old-age-socialise-ac... |
Description | Media coverage for 'Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study'. The Telegraph article 'How a healthy social life in middle age could protect against dementia' |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage ensuring that study results were available to a wider audience, including the general public. Further interest in the study generated. |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.telegraph.co.uk/science/2019/08/02/healthy-social-life-middle-age-could-protect-against-... |
Description | Media coverage for 'Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies' Kivimaki et al. Daily Express article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.pressreader.com/uk/daily-express/20210819/282192244062506 |
Description | Media coverage for 'Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies' Kivimaki et al. Daily Mail article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.dailymail.co.uk/health/article-9904657/Having-interesting-mentally-stimulating-job-cuts-... |
Description | Media coverage for 'Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies' Kivimaki et al. Perth Now article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.perthnow.com.au/technology/stimulating-jobs-may-lower-dementia-risk-c-3722462 |
Description | Media coverage for 'Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies' Kivimaki et al. Sky News article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://news.sky.com/story/mentally-stimulating-jobs-could-lower-the-risk-of-dementia-research-says-... |
Description | Media coverage for 'Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies'. Kivimaki et al. The Times article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.thetimes.co.uk/article/chief-executives-have-lower-dementia-risk-than-farmers-2pr03gg5m |
Description | Media coverage for 'Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies'. Kivimaki et al. 7News article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://7news.com.au/lifestyle/health-wellbeing/stimulating-jobs-may-lower-dementia-risk-c-3722472 |
Description | Media coverage for 'Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies'. Kivimaki et al. Belfast Telegraph article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.belfasttelegraph.co.uk/news/uk/dementia-risk-lower-for-people-in-mentally-stimulating-jo... |
Description | Media coverage for 'Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies'. Kivimaki et al. Express article. . |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.express.co.uk/life-style/health/1479909/dementia-cognitively-stimulating-work-low-risk |
Description | Media coverage for 'Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies'. Kivimaki et al. Guardian article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media interest generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.theguardian.com/society/2021/aug/19/dementia-risk-lower-for-people-in-stimulating-jobs-r... |
Description | Media coverage for 'Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies'. Kivimaki et al. Health and Life News article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://healthandlifenews.com/dementia-risk-lower-for-people-in-stimulating-jobs-research-suggests/ |
Description | Media coverage for 'Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies'. Kivimaki et al. The Irish Times article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.irishtimes.com/news/health/dementia-risk-lower-for-people-in-stimulating-jobs-study-sugg... |
Description | Media coverage for 'Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts'. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Alzheimer's Research Association: A New Dementia Risk Study Finds 11 Key Causes Of The Condition. This brought attention to the study and increased requests for further information. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.alzra.org/blog/a-new-dementia-risk-study-finds-11-key-causes-of-the-condition/ |
Description | Media coverage for 'Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts'. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Public/other audiences |
Results and Impact | The Standard new article: New study reveals 11 key factors that could increase dementia risk. This brought attention to the study and increased requests for further information. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.standard.co.uk/news/health/key-factors-increase-dementia-risk-new-study-b1103024.html |
Description | Media coverage for 'Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts'. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | The Independent new article: Revealed: 11 signs that show if you'll get dementia in next 14 years. This brought attention to the study and increased requests for further information. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.independent.co.uk/news/health/dementia-predictors-symptoms-b2398704.html |
Description | Media coverage for 'Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts'. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Alzheimer's Society article: New risk score strongly predicts dementia chances. This brought attention to the study and increased requests for further information. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.alzheimers.org.uk/news/2023-08-25/new-risk-score-strongly-predicts-dementia-chances |
Description | Media coverage for 'Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts'. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Medical News Today article: Screening tool uses 11 risk factors to predict dementia with up to 80% accuracy. Media interest brought attention to the study and results. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.medicalnewstoday.com/articles/screening-tool-uses-11-risk-factors-to-predict-dementia-wi... |
Description | Media coverage for 'Metabolomic profiles predict individual multidisease outcomes.' Hamburger Abendblatt article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Hamburger Abendblatt article: Cancer and Co: New method makes diseases predictable. This brought attention to the study ongoing research. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.abendblatt.de/vermischtes/article236499865/charite-studie-frueherkennung-krankheiten-dia... |
Description | Media coverage for 'Metabolomic profiles predict individual multidisease outcomes.' Medical News article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Medical News article: The potential of NMR-based blood profiling as a single-domain assay to simultaneously predict multidisease onset. Highlighting research and bringing attention to the study. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.news-medical.net/news/20220927/The-potential-of-NMR-based-blood-profiling-as-a-single-do... |
Description | Media coverage for 'Metabolomic profiles predict individual multidisease outcomes.' Medical Press |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Medical Press article: The predictive power of blood: Metabolomic profiling reveals risk of multiple diseases all at once. Media brought attention to the study and ongoing research. |
Year(s) Of Engagement Activity | 2022 |
URL | https://medicalxpress.com/news/2022-09-power-blood-metabolomic-profiling-reveals.html |
Description | Media coverage for 'Sex differences and the role of education in cognitive ageing: analysis of two UK-based prospective cohort studies'. Mail on Sunday news article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2021 |
URL | http://www.mailonsunday.co.uk/news/article-9199611/Women-75-risk-dementia-men-generation.html |
Description | Media coverage for 'Sex differences and the role of education in cognitive ageing: analysis of two UK-based prospective cohort studies'. McKnights.com news article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.mcknights.com/news/clinical-news/education-changes-may-account-for-reduced-sex-differenc... |
Description | Media coverage for 'Sex differences and the role of education in cognitive ageing: analysis of two UK-based prospective cohort studies'. Neuroscience.com news article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2021 |
URL | http://neurosciencenews.com/women-aging-dementia-education-17644/ |
Description | Media coverage for 'Sex differences and the role of education in cognitive ageing: analysis of two UK-based prospective cohort studies'. Telegraph news article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2021 |
URL | http://www.telegraph.co.uk/news/2021/01/29/older-women-greater-risk-dementia-due-poor-access-educati... |
Description | Media coverage for 'Sex differences in functional limitations and the role of socioeconomic factors: a multi-cohort analysis' Bloomberg et al. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Press release: Better access to education reduces differences in cognitive capacity between men and women: High level of media coverage generting further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://presse.inserm.fr/en/better-access-to-education-reduces-differences-in-cognitive-capacity-bet... |
Description | Media coverage for 'Sex differences in functional limitations and the role of socioeconomic factors: a multi-cohort analysis' Bloomberg et al. Daily Mail article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.dailymail.co.uk/wires/pa/article-10244325/Women-struggle-men-daily-tasks-age--study.html |
Description | Media coverage for 'Sex differences in functional limitations and the role of socioeconomic factors: a multi-cohort analysis' Bloomberg et al. Evening Standard article |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.standard.co.uk/news/uk/women-ucl-national-institute-for-health-research-bloomberg-europe... |
Description | Media coverage for 'Sex differences in functional limitations and the role of socioeconomic factors: a multi-cohort analysis' Bloomberg et al. INSERM press release. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Media coverage for 'Sex differences in functional limitations and the role of socioeconomic factors: a multi-cohort analysis' Bloomberg et al. |
Year(s) Of Engagement Activity | 2021 |
URL | https://presse.inserm.fr/en/better-access-to-education-reduces-differences-in-cognitive-capacity-bet... |
Description | Media coverage for 'Sex differences in functional limitations and the role of socioeconomic factors: a multi-cohort analysis' Bloomberg et al. News Medical article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.news-medical.net/news/20211126/Women-more-likely-than-men-to-struggle-with-daily-activit... |
Description | Media coverage for 'Sex differences in functional limitations and the role of socioeconomic factors: a multi-cohort analysis' Bloomberg et al. UCL News. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Press release: Lack of sleep in middle age linked to dementia risk: High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.ucl.ac.uk/news/headlines/2021/nov/women-struggle-more-men-daily-tasks-they-age |
Description | Media coverage for 'Sex differences in functional limitations and the role of socioeconomic factors: a multi-cohort analysis' Bloomberg et al. Wales online article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage generating further interest in the study. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.walesonline.co.uk/news/uk-news/women-struggle-more-men-daily-22281191 |
Description | Media coverage for Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II cohort |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Public/other audiences |
Results and Impact | Washington Post news article: Sleeping under 5 hours when over 50 adds to health risks, study warns. This media attracted attention to the study and increased requested for further information. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.washingtonpost.com/wellness/2022/10/19/sleep-five-hours-chronic-diseases-study/ |
Description | Media coverage for Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II cohort study. BBC News |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | BBC News item 'Five hours' sleep is tipping point for bad health'. This media brought attention to the study and increased requests for further information. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.bbc.co.uk/news/health-63284305 |
Description | Media coverage for Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | The Guardian article: Dementia risk study finds 11 key factors behind condition. Predictive tool 'significantly outperforms' others available and could help avert about 40% of cases. Media brought attention to the study and ongoing research. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.theguardian.com/society/2023/aug/24/dementia-risk-study-finds-11-key-factors-behind-cond... |
Description | Mika Kivimaki. Prevention for tackling the growing burden of non-communicable diseases. Stockholm Insurance Medicine Lecture of Year 2021. Stockholm, 9 November, 2021 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Professional Practitioners |
Results and Impact | Presentation: Prevention for tackling the growing burden of non-communicable diseases. Prof. Mika Kivimaki |
Year(s) Of Engagement Activity | 2021 |
Description | Mika Kivimaki. Social Determinants of Metabolic Health-Evidence from Human Populations. American Diabetes Association, Discovery Awaits You at the 81st Scientific Sessions, Virtual, June 25-29, 2021. (Mini-symposium) |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Presentation: Influence of Social Inequalities and Social Stress on Metabolic Health Social Determinants of Metabolic Health-Evidence from Human Populations. Prof Mika Kivimäki. |
Year(s) Of Engagement Activity | 2021 |
URL | https://professional.diabetes.org/sites/professional.diabetes.org/files/media/2021_final_program_-_f... |
Description | Oral presentation 'Change in heart rate and heart rate variability is not related to cardiovascular events or death, irrespective of dysglycaemia: Downfall of risk markers?' Adam Tabak |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Oral presentation at the EASD 'Change in heart rate and heart rate variability is not related to cardiovascular events or death, irrespective of dysglycaemia: Downfall of risk markers? The Whitehall II study' Hansen C. |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.easd.org/virtualmeeting/home.html#!resources/change-in-heart-rate-and-heart-rate-variabi... |
Description | Poster presentation 'Association of Social Network Contact with Risk of Dementia and Cognitive Decline: 28-Year Follow-up of the Whitehall II Cohort Study'. Alzheimer's Association International Conference July 2019. |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Presentation generated a high level of interest and sparked questions and discussion from observers. |
Year(s) Of Engagement Activity | 2019 |
Description | Presentation: The effect of diabetic sensory peripheral neuropathy on mortality - a meta-analysis. 54th Annual EDEG Meeting, Luxembourg, 11-14 May 2019. Adam Tabak |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Presentation sparked questions and discussions and generated interest in the data. |
Year(s) Of Engagement Activity | 2019 |
Description | Presentation: The effect of diabetic sensory peripheral neuropathy on mortality: a meta-analysis. 55th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Barcelona. Adam Tabak. |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Presentation sparking questions and answers and generating interest in results. |
Year(s) Of Engagement Activity | 2019 |
Description | Press Release:Association of sleep duration at age 50, 60, and 70 years with risk of multimorbidity in the UK: 25-year follow-up of the Whitehall II cohort study. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Press Release: Less than five hours' sleep a night linked to higher risk of multiple diseases |
Year(s) Of Engagement Activity | 2022 |
URL | http://www.sciencedaily.com/releases/2022/10/221018220538.htm |
Description | Press release by the University of Exeter on 'Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour'. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Press Release: 'Research identifies genetic causes of poor sleep' on Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour. High level of media coverage generating interest in the study. |
Year(s) Of Engagement Activity | 2019 |
URL | https://www.eurekalert.org/pub_releases/2019-04/uoe-rig040419.php |
Description | Press release for 'Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption with Risk for Dementia'. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | https://www.eurekalert.org/pub_releases/2020-09/jn-aoa090420.php |
Description | Press release for 'Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts'. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | BMJ Press release: New risk score strongly predicts dementia chances within 14 years. This brought attention to the study and increased requests for further information. |
Year(s) Of Engagement Activity | 2023 |
URL | https://www.bmj.com/company/newsroom/new-risk-score-strongly-predicts-dementia-chances-within-next-1... |
Description | Prevention for tackling the growing burden of non-communicable diseases. Stockholm Insurance Medicine Lecture of Year 2021. Stockholm, 9 November, 2021 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Professional Practitioners |
Results and Impact | Presentation: Prevention for tackling the growing burden of non-communicable diseases. Prof. Mika Kivimaki |
Year(s) Of Engagement Activity | 2021 |
URL | https://professional.diabetes.org/sites/professional.diabetes.org/files/media/2021_final_program_-_f... |
Description | Risk of micro- and macrovascular disease in persons diagnosed with diabetes by an OGTT (later confirmed or not confirmed by an HbA1c) - the Whitehall II study. |
Form Of Engagement Activity | A magazine, newsletter or online publication |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Patients, carers and/or patient groups |
Results and Impact | This was an article on the webpage of Semmelweis University that reaches University workers and the general public |
Year(s) Of Engagement Activity | 2023 |
URL | https://semmelweis.hu/hirek/2023/01/03/tudomanyos-hirado-13/ |
Description | Sabia S. Alzheimer Association International Conference (AAIC) 2021, 28/07/2021, Chair of the Session "Epidemiology: Lifecourse and cohort perspectives on cognitive decline and dementia" |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Other audiences |
Results and Impact | Sabia S. Alzheimer Association International Conference (AAIC) 2021, 28/07/2021, Chair of the Session "Epidemiology: Lifecourse and cohort perspectives on cognitive decline and dementia" |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.alz.org/aaic/highlights2021.asp |
Description | Sabia S. Invited talk to the Alzheimer's association Journal club. Talk to the author. 2nd of December 2021. |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Postgraduate students |
Results and Impact | Sabia S. Association of sleep duration in middle and old age with incidence of dementia. Invited talk to the Alzheimer's association Journal club. Talk to the author. 2nd of December 2021. |
Year(s) Of Engagement Activity | 2021 |
URL | https://training.alz.org/products/4264/istaart-journal-club-meet-the-author |
Description | Sabia S. Sleep duration at 50, 60 and 70 and risk of onset of dementia during ageing. Symposium: Impact of sleep on cognitive functions from children to the elderly. Congrès du sommeil. Lille. 25-26 November 2021. |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Professional Practitioners |
Results and Impact | Presentation: Sleep duration at 50, 60 and 70 and risk of onset of dementia during ageing. Symposium: Impact of sleep on cognitive functions from children to the elderly. Congrès du sommeil. Lille. 25-26 November 2021. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.lecongresdusommeil.com/ |
Description | Scientific Committee, the French National Alzheimer database (BNA). Prof Archana Singh-Manoux |
Form Of Engagement Activity | A formal working group, expert panel or dialogue |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Patients, carers and/or patient groups |
Results and Impact | National network to shape care of dementia patients. |
Year(s) Of Engagement Activity | 2019 |
URL | http://www.innovation-alzheimer.fr/bna-en/ |
Description | Semmelweis Study (SeS) - study design. Healthy Aging Symposium, 2022 Semmelweis Symposium, Budapest, Hungary, 8 November 2022 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Semmelweis Symposium is the most prestigious annual scientific event of Semmelweis University, which presents the latest scientific results and innovations and is an excellent forum for international knowledge transfer and networking. |
Year(s) Of Engagement Activity | 2022 |
URL | https://semmelweis.hu/symposium/en/about-semmelweis-symposium/ |
Description | The newest evidence related to the treatment of type 1 diabetes. Insulin treatment accompanied by CGM: novel aspects of basal insulin treatment. Diabetes in the 21st Century. New Challenges and Answers). 01.10.2022, Budapest, Hungary |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Professional Practitioners |
Results and Impact | This was a continuous medical education event for diabetes specialists |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.convention.hu/Rendezveny/Reszletek/UM22 |
Description | The use of metabolic trajectories to better describe the natural history of metabolic diseases. EUniWell Open Lecture Series, Virtual, 7 April 2022 |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Recognised scholars, scientists and educators from EUniWell partner universities presented well-founded analyses of well-being issues and new findings related to one of the 4 key EUniWell Arenas. |
Year(s) Of Engagement Activity | 2022 |
URL | https://www.euniwell.eu/what-we-offer/educational-offer/euniwell-open-lecture-series |
Description | UK Biobank Dementia Working Group Workshop, 10/10/2022 |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Professional Practitioners |
Results and Impact | Discussion on important measures to be added to future wave of UK Biobank data collection |
Year(s) Of Engagement Activity | 2022 |
Description | UK-JAPAN ESRC funded symposium on ageing and health |
Form Of Engagement Activity | Participation in an activity, workshop or similar |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Postgraduate students |
Results and Impact | Launch of research networking activity on ageing and health. |
Year(s) Of Engagement Activity | 2019 |
Description | Virtual EASD Annual Meeting 2020 Poster Presentation. The effect of occupational position on aging trajectories of glycaemic measures in non-diabetic individuals: The Whitehall II study Poster |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | The effect of occupational position on aging trajectories of glycaemic measures in non-diabetic individuals: The Whitehall II study Poster #335. Poster generated further interest in the Whitehall II Study. |
Year(s) Of Engagement Activity | 2020 |
URL | https://www.abstractsonline.com/pp8/#!/9143/presentation/1518 |
Description | Women struggle more than men with daily tasks as they age Tasks like climbing stairs, lifting groceries or using the phone may be more difficult for women than men as they age, finds a new study led by PhD candidate, Mikaela Bloomberg (UCL Institute of Epidemiology & Health). |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Press release generated a high level of media coverage. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.ucl.ac.uk/news/headlines/2021/nov/women-struggle-more-men-daily-tasks-they-age |
Description | Women struggle more than men with daily tasks as they age Tasks like climbing stairs, lifting groceries or using the phone may be more difficult for women than men as they age, finds a new study led by PhD candidate, Mikaela Bloomberg (UCL Institute of Epidemiology & Health). |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Media (as a channel to the public) |
Results and Impact | Press release: Sex differences in functional limitations and the role of socioeconomic factors: a multi-cohort analysis. Bloomberg et al. Press release generated a high level of media coverage. |
Year(s) Of Engagement Activity | 2021 |
URL | https://www.ucl.ac.uk/news/headlines/2021/nov/women-struggle-more-men-daily-tasks-they-age |
Description | media coverage for 'A life-time of hazardous drinking and harm to health among older adults: findings from the Whitehall II prospective cohort study'. Daily Mail news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.dailymail.co.uk/sciencetech/article-8172473/Drinking-middle-age-add-nearly-TWO-INCHES-wai... |
Description | media coverage for 'A life-time of hazardous drinking and harm to health among older adults: findings from the Whitehall II prospective cohort study'. ITV.com news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.itv.com/news/2020-04-01/heavy-drinking-into-older-age-adds-4cm-to-waistline/ |
Description | media coverage for 'A life-time of hazardous drinking and harm to health among older adults: findings from the Whitehall II prospective cohort study'. Irish News news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.irishnews.com/magazine/science/2020/03/31/news/heavy-drinking-into-older-age-adds-4cm-to-... |
Description | media coverage for 'A life-time of hazardous drinking and harm to health among older adults: findings from the Whitehall II prospective cohort study'. Telegraph news article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://www.telegraph.co.uk/news/2020/03/31/heaving-drinking-adds-four-centimeters-waistline-ucl-stud... |
Description | media coverage for 'A life-time of hazardous drinking and harm to health among older adults: findings from the Whitehall II prospective cohort study'. lnews article. |
Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Public/other audiences |
Results and Impact | High level of media coverage. |
Year(s) Of Engagement Activity | 2020 |
URL | http://inews.co.uk/news/health/mps-civil-servants-drinking-alcohol-2524704 |
Description | • Presentation: e-poster 'High ultra-processed foods intake is associated with increased odds of recurrent depressive symptoms in British cohort' at European congress of Psychiatry 2022, June 4th - 7th. |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | International |
Primary Audience | Professional Practitioners |
Results and Impact | Presentation: e-poster 'High ultra-processed foods intake is associated with increased odds of recurrent depressive symptoms in British cohort' at European congress of Psychiatry 2022, June 4th - 7th. Husnain Arshad. |
Year(s) Of Engagement Activity | 2022 |
URL | https://2022.epa-congress.org/scientific-programme/ |