The exploitation of mannosyltransferase inhibitors to modulate glycoprotein biogenesis and quality control
Lead Research Organisation:
The University of Manchester
Department Name: School of Biological Sciences
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
People |
ORCID iD |
| Stephen High (Primary Supervisor) | |
| Sarah O'Keefe (Student) |
Publications
Gamayun I
(2019)
Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum.
in Cell chemical biology
O'Keefe S
(2019)
Characterizing the selectivity of ER a-glucosidase inhibitors.
in Glycobiology
Steenhuis M
(2021)
Eeyarestatin 24 impairs SecYEG-dependent protein trafficking and inhibits growth of clinically relevant pathogens.
in Molecular microbiology
Zong G
(2020)
Ring Expansion Leads to a More Potent Analogue of Ipomoeassin F.
in The Journal of organic chemistry
Zong G
(2019)
Ipomoeassin F Binds Sec61a to Inhibit Protein Translocation.
in Journal of the American Chemical Society
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| BB/M011208/1 | 30/09/2015 | 31/03/2024 | |||
| 1618828 | Studentship | BB/M011208/1 | 30/09/2015 | 29/09/2019 | Sarah O'Keefe |