Unsteady Aerodynamics and Acoustics for Practical Biological Applications.
Lead Research Organisation:
University of Cambridge
Department Name: Engineering
Abstract
Aerodynamics and Acoustics are mature fields, but their application to practical biological applications has been limited and is a high impact area for future research. In particular the fluid dynamics and aerodynamics of flows within the human body, and the mechanisms by which these flows generate and propagate sound is an open question. Understanding these flows, the generation of sounds and the nonlinear systems that govern the propagation of these sounds through human tissue is the first aim of this research project. This will involve analytical and numerical modelling as well as experiments performed in collaboration with hospitals. The second and ultimate aim is to use an improved understanding of the above-described systems to develop the modern equivalent of a stethoscope, a device that revolutionised clinical medicine when it was introduced 200 years ago. The development of this clinical technology will require not only an improved understanding of the physics of the systems, but also engineering design to develop a device that employs sensors and instrumentation, machine learning and physical insight into a clinical technology that will be present cheap and readily available alternative to other medical imaging techniques.
People |
ORCID iD |
Anurag Agarwal (Primary Supervisor) | |
Maximilian Nussbaumer (Student) |
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
EP/N509620/1 | 01/10/2016 | 30/09/2022 | |||
1779588 | Studentship | EP/N509620/1 | 01/10/2016 | 30/09/2020 | Maximilian Nussbaumer |
Description | We have developed a new theory for stethoscope acoustics by combining a number of analytical modelling techniques with experimental data. |
Exploitation Route | Our models can be used to understand existing stethoscopes and improve the design of new devices. |
Sectors | Healthcare,Pharmaceuticals and Medical Biotechnology |
Description | Acoustic Lab - Respiratory Medicine collaboration for clinical study |
Organisation | Cambridge University Hospitals NHS Foundation Trust |
Country | United Kingdom |
Sector | Public |
PI Contribution | This collaboration was set up to investigate sound propagation through the human body (in particular the lungs) in the context of improving diagnosis using biological sounds. We designed the study, developed the study protocol and documentation, obtained ethics approval, designed and assembled the equipment and are now collecting the data and analysing the results. |
Collaborator Contribution | CUH (Cambridge University Hospitals NHS Foundation Trust) are the sponsors for the clinical study at the centre of this collaboration. Members of the Respiratory Medicine team at CUH gave advice on the design of the study. The R&D team at CUH assisted in the development of the study protocol and documentation and in obtaining ethics approval. The Clinical Engineering team at CUH gave guidance on the design of equipment for use in a clinical setting and carried out the safety testing of the equipment. The Clinical Research Facility at CUH are providing a facility at which acoustic measurements can be taken, as well as trained research nurses to assist with the study. Our key partners in the Respiratory Medicine team are actively sourcing participants for the study, carrying out the Bronchoscopies which the clinical study makes use of, providing diagnostic information on the study participants and assisting in the data collection process. |
Impact | This collaboration is multi-disciplinary. The disciplines involved are: Acoustics Engineering Respiratory Medicine The clinical study is currently active. |
Start Year | 2016 |
Description | Acoustics Lab Talk & Tour - (Engineering Department Open Day) |
Form Of Engagement Activity | Participation in an open day or visit at my research institution |
Part Of Official Scheme? | No |
Geographic Reach | National |
Primary Audience | Schools |
Results and Impact | As part of the Cambridge University Open Days I gave short talks about acoustics research and tours of the acoustics lab. Several hundred sixth-form students and parents/guardians attended over two afternoons. Many audience members had not been aware of acoustics as an area of engineering research and engagement/interest was high. |
Year(s) Of Engagement Activity | 2017,2018 |
Description | Science Festival Pecha Kucha Talk |
Form Of Engagement Activity | A talk or presentation |
Part Of Official Scheme? | No |
Geographic Reach | Regional |
Primary Audience | Public/other audiences |
Results and Impact | Roughly 50 members of the general public attended the Pecha Kucha event, which was run as part of the Cambridge Science Festival. I gave a talk about my work in the 20*20s Pecha Kucha format. |
Year(s) Of Engagement Activity | 2018 |