Epigenetic mechanisms of androgen signalling: influences on RNA methylation and transcriptional regulation
Lead Research Organisation:
University of Nottingham
Department Name: School of Veterinary Medicine and Sci
Abstract
Androgens are essential for normal male embryonic and pubertal development and are implicated in multiple cancer types. Androgens, acting via the androgen receptor (AR), regulate transcription of target genes by recruiting multiple epigenetic coregulators which cooperate to modify chromatin and thereby regulate transcription. In addition we have exciting new evidence that androgen signaling exploits changes in RNA epigenetics to modulate gene expression.
Organisations
People |
ORCID iD |
| Nigel Mongan (Primary Supervisor) | |
| Jeremy Roberts (Primary Supervisor) |
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| BB/M008770/1 | 01/10/2015 | 31/10/2024 | |||
| 1803097 | Studentship | BB/M008770/1 | 01/10/2016 | 31/03/2021 |
| Description | March for Men |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Fellow postgraduate students and I attended the Nottingham March for Men Prostate cancer UK event in 2018. We hosted a stall during the event for which we prepared posters and interactive games for the general public. Throughout the day we engaged with those doing the walk, supporters, clinicians and PCUK charity workers at a range of levels. We were involved in a Facebook Live segment by PCUK featuring an insight to our research and where future funding will be invested. We also helped to raise money for PCUK by selling charity PCUK accessories. |
| Year(s) Of Engagement Activity | 2018 |
| URL | https://prostatecanceruk.org/get-involved/march-for-men/the-nottingham-march-for-men |