Zebrafish as a model to study mechanisms of nociception

Lead Research Organisation: University College London
Department Name: Cell and Developmental Biology

Abstract

Potentially harmful stimuli are detected at the skin by nociceptor sensory neurons that drive rapid protective withdrawal behaviours. It is unclear how the somatosensory system encodes and integrates information from stimuli causing pain. Here we will use a number of advanced technologies to understand the role of the somatosensory cortex in encoding and integrating nociceptive information to coordinate appropriate protective responses to noxious stimuli. This should provide exciting new insights into how the nervous system guides behavioural responses to minimise risk of harm.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
BB/M009513/1 01/10/2015 31/03/2024
1902551 Studentship BB/M009513/1 01/10/2017 30/04/2022 Elisa Clemente
 
Description Research smorgasbord 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Members of the general public at the "It's all academic festival" at UCL shared a table with researchers across disciplines and experienced world-leading research in a convivial atmosphere.
Year(s) Of Engagement Activity 2019
 
Description The Brilliant Club tutor 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact 10 school pupils (years 9 and 10) attended 6 tutorials delivered by me on the subject of pain and pain research. This sparked several questions and discussions. The lead teacher reported increased interest in the subject.
Year(s) Of Engagement Activity 2019