Analysis of how specific RNA motifs in HIV-1 and lentiviral vector genomes control infectious virus production
Lead Research Organisation:
King's College London
Department Name: Immunology Infection and Inflam Diseases
Abstract
We hypothesise that an innate immune pathway recognises HIV-I RNA containing CpG dinucleotides and inhibits viral replication. This project will analyse how CpG dinucleotides in the HIV-I genome and lentivirat vector genomes are sensed by the innate immune system and inhibit viral replication.
Organisations
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
MR/R50225X/1 | 01/10/2017 | 30/04/2024 | |||
1939180 | Studentship | MR/R50225X/1 | 01/10/2017 | 30/06/2021 | Mattia Ficarelli |