Computational modelling of information transfer between cells

Lead Research Organisation: University of East Anglia
Department Name: Graduate Office

Abstract

The exchange of information and resources between cells and tissues enables co-ordination of responses to environmental and developmental signals. In plants, the cytoplasm of adjacent cells is connected by intercellular 'tunnels' that cross the cell wall, allowing for the exchange of molecules. These tunnels can regulate traffic between cells which is of particular importance during pathogen attack. Yet how this information flow is regulated remains largely unknown.
Using computational models this project will unravel of how molecules are transported from cell to cell to shed light on the mechanisms that underpin information flow within plants. The successful applicant will be part of an interdisciplinary team working on cell signalling, with leading researchers in mathematical systems biology and plant cell biology. This project is well suited for someone with a physics, maths or computing background who has an interest in biology or a biologist with strong numerical skills.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
BB/M011216/1 01/10/2015 30/09/2023
2060831 Studentship BB/M011216/1 01/10/2018 30/09/2022 Nathan Hughes