Optimising sonodynamic therapy for the treatment of prostate cancer
Lead Research Organisation:
University College London
Department Name: Surgical Biotechnology
Abstract
Aim: The main aim of the project is to develop and establish the efficacy of porphyrin-carrying nanoparticles for enhancing the effect of SDT in the treatment of prostate tumours.
Key Hypothesis: Firstly, that porphyrin-containing nanoparticles that are degraded in tumour-like conditions have improved prostate tumour accumulation and tumour diffusion profiles. Secondly, that porphyrin-containing nanoparticles with improved prostate tumour accumulation profile can improve the antitumour efficacy of SDT and lead to the optimisation of this therapeutic modality for prostate cancer treatment.
Key Hypothesis: Firstly, that porphyrin-containing nanoparticles that are degraded in tumour-like conditions have improved prostate tumour accumulation and tumour diffusion profiles. Secondly, that porphyrin-containing nanoparticles with improved prostate tumour accumulation profile can improve the antitumour efficacy of SDT and lead to the optimisation of this therapeutic modality for prostate cancer treatment.
Organisations
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| EP/R513143/1 | 01/10/2018 | 30/09/2023 | |||
| 2270591 | Studentship | EP/R513143/1 | 30/09/2019 | 29/12/2023 | Hamzah Masood |