Investigating the functional role of exosomal RNA cargo in medulloblastoma metastasis

Lead Research Organisation: University of Nottingham
Department Name: School of Medicine

Abstract

The project involves bioinformatic analysis and validation of RNASeq data (mRNA, lncRNA and miRNA) from medulloblastoma exosomes. Data sets from primary and matched metastatic and primary tumour derived cell lines will be compared, in order to identify candidates that potentially play a role in cell migration. These will be validated in functional assays and the underlying mechanism determined.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
BB/M008770/1 01/10/2015 31/10/2024
2275841 Studentship BB/M008770/1 01/10/2019 25/11/2023