Novel chemical approaches to understand protein prenylation

Lead Research Organisation: Imperial College London
Department Name: Dept of Chemistry

Abstract

Protein prenylation is a universally important post-translational modification (PTM) in cells, and plays a role in many diseases. Here we will develop novel chemical probes to study this class of PTM, and apply this physical science innovation to understand the role and mode of action of drugs currently undergoing clinical trials in cancer.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/S023518/1 01/10/2019 31/03/2028
2282978 Studentship EP/S023518/1 01/10/2019 30/09/2022 Sarah Hassan