Understanding Neuroplasticity Induced by TrYptamines (UNITY)
Lead Research Organisation:
University College London
Department Name: Experimental Psychology
Abstract
Serotonergic psychedelics have broad therapeutic potential as a novel psychiatric
intervention across a range of disorders. They also promote mental wellbeing in 'healthy'
people. Despite these demonstrations, we have little insight into the mechanisms of
therapeutic change following psychedelics. A likely candidate is neural plasticity though there
have been few direct tests. This project examines changes in the network organization of the
human brain after a single administration of dimethyltryptamine (DMT) using functional
magnetic resonance imaging (fMRI). Network measures will be used to predict clinically
relevant benefits in heavy drinkers and improvements in well-being in typical populations.
intervention across a range of disorders. They also promote mental wellbeing in 'healthy'
people. Despite these demonstrations, we have little insight into the mechanisms of
therapeutic change following psychedelics. A likely candidate is neural plasticity though there
have been few direct tests. This project examines changes in the network organization of the
human brain after a single administration of dimethyltryptamine (DMT) using functional
magnetic resonance imaging (fMRI). Network measures will be used to predict clinically
relevant benefits in heavy drinkers and improvements in well-being in typical populations.
Organisations
People |
ORCID iD |
Jeremy Skipper (Primary Supervisor) | |
Regan Harle (Student) |
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
BB/T008709/1 | 30/09/2020 | 29/09/2028 | |||
2396688 | Studentship | BB/T008709/1 | 30/09/2020 | 29/09/2024 | Regan Harle |