A Multiscale Modelling Approach to Study the Effects and Responses of DNA Damage Response (DDR) Inhibitor Drugs

Lead Research Organisation: Swansea University
Department Name: College of Science

Abstract

This project aims to develop multiscale experimental data-driven mathematical and computational models to study and analyze the effects and efficacy of DNA damage response inhibiting drugs. The model will be used to study optimal sequencing, scheduling, and dosing alone and in combination with multimodality therapies. It will also be used to inform in vivo and preclinical studies.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/T517987/1 01/10/2020 30/09/2025
2435018 Studentship EP/T517987/1 01/10/2020 30/09/2023 Kira Pugh