Investigating the mechanisms of cell-surface receptor clustering in virus entry

Lead Research Organisation: University College London
Department Name: Physics and Astronomy

Abstract

This PhD project will focus on developing novel simulations of receptor clustering in cell membranes. To infect a cell, viruses must penetrate cellular membrane barriers. Viruses engage specific receptors that typically cluster on the cell-surface upon virus binding, facilitating the molecular interactions that lead to penetration. Receptor clustering is known to influence the entry of viruses into cells, and so this research will have broad applicability to virus infection.

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/R513143/1 01/10/2018 30/09/2023
2580891 Studentship EP/R513143/1 01/10/2021 30/09/2025 Chawntell Kulkarni