Modelling, optimisation, and control in biomedical engineering
Lead Research Organisation:
University of Cambridge
Department Name: Chemical Engineering and Biotechnology
Abstract
Project on personalised medicine centred on mathematical modelling of bacterial infections in human hosts. The project involves producing a WB-PBPK (Whole Body Physiologically-Based Pharmacokinetic Model), suitable for describing (potentially mixed) bacteria populations with varying degrees of anti-microbial resistance, and applying modern optimisation methods to the specification of antimicrobial therapies. The mathematical optimisation methods are the speciality of the research group; these methods were designed to select optimal schedules for optimising chemical plant performance, and applying them to the analogous task of optimising a medical therapy within a human organism is highly innovative and potentially very impactful interdisciplinary project.
Organisations
People |
ORCID iD |
Sebastian Ahnert (Primary Supervisor) | |
Nikolaos Katritsis (Student) |
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
EP/R513180/1 | 01/10/2018 | 30/09/2023 | |||
2595551 | Studentship | EP/R513180/1 | 01/10/2019 | 30/09/2021 | Nikolaos Katritsis |