Photoacoustic imaging for the optimisation of CAR-T cell cancer therapy of soft-tissue tumours A metrology and system development
Lead Research Organisation:
University of Surrey
Department Name: Vision Speech and Signal Proc CVSSP
Abstract
This project aims to develop and evaluate the use of photoacoustic imaging for determining the biodistribution of the CAR-T cells in vivo. The project objectives include: development of methodologies for photoacoustic quantification of tumour and/or CAR-T cell numbers and assessment of their performance in tissue-mimicking phantoms;validating the methods for cell number quantification in vivo; exploring the application to the dynamic quantification of CAR-T cell numbers as they penetrate tumours; evaluating alternative ultrasound array configurations and noise reduction methods to improve performance for CAR-T cell tracking in vivo
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
EP/V519789/1 | 01/10/2020 | 30/09/2025 | |||
2596279 | Studentship | EP/V519789/1 | 01/10/2021 | 30/09/2025 | Somayya Manzoor |