Designing Bridges between Radical and Organometallic Reactivity

Lead Research Organisation: University of Strathclyde
Department Name: Pure and Applied Chemistry


This project explores the role of ligands and reaction conditions in (i) directing organometallic complexes to take radical pathways, and (ii) diverting radical reactions to give organometallic outcomes. We will initially concentrate on palladium and nickel as the metals. The aim is to give access to catalytic and chain reactions that are otherwise not feasible. DFT methods will be deployed to interrogate the reactivity of putative complexes and radicals, thereby rationalising experimental observations and guiding reaction design. Opportunities to develop a computational model through machine learning in collaboration with GSK will be pursued. The project aligns closely with EPSRC research areas of Catalysis, Synthetic Organic Chemistry and Computational and Theoretical Chemistry


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Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/W522260/1 30/09/2021 29/09/2026
2606869 Studentship EP/W522260/1 30/09/2021 29/09/2025 Sebastian Tyerman