Computational modelling of myosin mutants for the treatment of congenital myopathies
Lead Research Organisation:
Queen Mary University of London
Department Name: Chemistry
Abstract
Modelling the dynamics of the fast type II-a skeletal myosin (encoded by MYH2 gene) in MD simulations and comparing its dynamics with different mutants (Missense mutation specifically). The binding pocket for drugs will also be characterised and ready for virtual screening.
People |
ORCID iD |
| Arianna Fornili (Primary Supervisor) | |
| Ka Fu Man (Student) |
Studentship Projects
| Project Reference | Relationship | Related To | Start | End | Student Name |
|---|---|---|---|---|---|
| EP/T518086/1 | 01/10/2020 | 30/09/2025 | |||
| 2773368 | Studentship | EP/T518086/1 | 01/10/2022 | 31/03/2026 | Ka Fu Man |