Engineering bio-recorders to permanently record environmental events in the yeast genome

Lead Research Organisation: University of Manchester
Department Name: Chemistry


We aim to engineer cellular recorders in yeast to track intracellular and extracelluar biological events over time across living cells and cell populations. This is a hardcore synthetic biology project, which is a priority area for the BBSRC. It will develop novel transformative technologies which allow researchers to capture environmental and cellular events by faithfully recording them into the genome. The project also involves mathematical and computational approaches to record, retrieve and error-correct biological and digital information. In terms of applications, biorecorders can be deployed to real time monitor human health (healthy country), chemical and biological threats (resilient country) and environmental impacts over an extended period of time.


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Studentship Projects

Project Reference Relationship Related To Start End Student Name
BB/T008725/1 30/09/2020 29/09/2028
2775622 Studentship BB/T008725/1 30/09/2022 29/09/2026 Gabrielle David