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Replacing Aldehydes in Reductive Amination

Lead Research Organisation: University of Edinburgh
Department Name: Sch of Chemistry

Abstract

This project will develop reductive amination directly from high oxidation-state carbonyl derivatives. The ability to perform reductive amination using high oxidation-state carbonyl coupling partners will introduce new chemical reactivity, open chemical space and greatly increase the operational simplicity of this transformation. Key to this advance is the in situ generation of an aldehyde equivalent and the engagement of this in the reductive amination reactions.

People

ORCID iD

Nathan McRae (Student)

Publications

10 25 50

Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/W524384/1 30/09/2022 29/09/2028
2870985 Studentship EP/W524384/1 31/08/2023 28/02/2027 Nathan McRae