Targeting Lung Cancer's 'Safe Space' with Novel p21 Peptides

Lead Research Organisation: Imperial College London
Department Name: Chemistry


p21 is a CDK inhibitor protein that can promote quiescence in Non-Small Cell Lung Cancer (NSCLC). Blocking p21 function in NSCLC cells leads to increased spontaneous cell death, increased sensitivity to chemotherapy and decreased frequency of clonal regrowth. The aim of this project is to generate p21-blocking peptides to block p21 function in NSCLC to improve patient outcomes.


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Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/S023518/1 30/09/2019 30/03/2028
2887025 Studentship EP/S023518/1 30/09/2023 29/09/2027 Lucy Dan