Developing A Structural Biology Driven Approach To Biofilm Control And Management.
Lead Research Organisation:
University of Southampton
Department Name: Sch of Biological Sciences
Abstract
Biofilms are controlled by the intracellular concentration of the secondary messenger c-di-GMP. Two linked PhDs address the role of multi-domain proteins as toggle switches in the management and control of biofilms. This PhD develops a novel structural biology approach to studying ligand controlled regulatory multi-domain proteins in biofilm dispersal. Together with the linked PhD that develop specific methods to influence multi-domain proteins known to control motility and dispersal. The two linked PhDs engage to integrate across discovery, dynamic molecular systems, and validation of targets.
Organisations
People |
ORCID iD |
Ivo Tews (Primary Supervisor) | http://orcid.org/0000-0002-4704-1139 |
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
BB/X017745/1 | 01/01/2023 | 31/03/2023 | |||
2891967 | Studentship | BB/X017745/1 | 01/11/2023 | 31/10/2027 |