Development of high-value chemicals bioproduction integrating metabolic engineering, Design of Experiments and entrepreneurship
Lead Research Organisation:
Imperial College London
Department Name: Life Sciences
Abstract
The use of genetically engineered strains to biomanufacture chemicals enables direct CO2-to-
product systems with vastly superior environmental sustainability (reduced GHGe) and synthesis
of isomer(s) with a purity not achieved by traditional chemistry. However, the engineering and
optimization of microbial bioproduction strains (essential components in the development of
biological manufacturing systems) is time-consuming and costly. Coupled with the uncertainty of
biological engineering, this leads to higher risk and a lower appetite for investment, making
commercialisation challenging. To enable SynBio to make a meaningful contribution to the
enormous fossil fuel problem, we propose to first commence with higher value beachhead target
products and solve current bottlenecks to developing viable solutions.
product systems with vastly superior environmental sustainability (reduced GHGe) and synthesis
of isomer(s) with a purity not achieved by traditional chemistry. However, the engineering and
optimization of microbial bioproduction strains (essential components in the development of
biological manufacturing systems) is time-consuming and costly. Coupled with the uncertainty of
biological engineering, this leads to higher risk and a lower appetite for investment, making
commercialisation challenging. To enable SynBio to make a meaningful contribution to the
enormous fossil fuel problem, we propose to first commence with higher value beachhead target
products and solve current bottlenecks to developing viable solutions.
Organisations
People |
ORCID iD |
Patrik Jones (Primary Supervisor) | |
Celine Caraffa (Student) |
Studentship Projects
Project Reference | Relationship | Related To | Start | End | Student Name |
---|---|---|---|---|---|
EP/S022856/1 | 31/03/2019 | 29/09/2027 | |||
2898855 | Studentship | EP/S022856/1 | 30/09/2023 | 29/09/2027 | Celine Caraffa |