Development and Screening of Novel Fungal Strains for Exploitation in the Food Industry
Lead Research Organisation:
University of Nottingham
Department Name: School of Life Sciences
Abstract
Fungi are used to produce a number of foodstuffs. This often involves the use of long-established strains, because it has proved difficult to produce new, improved strains for many species. However, we have developed a technology allowing us to sexually cross certain fungi used in the food industry and shown that this results in the generation of offspring with enhanced properties for use in food production. This includes production of strains with pleasurable novel flavours and appearance, and lowered toxin content. We now plan to take these strains and screen and develop them for commercial exploitation. We also plan to make more crosses to generate offspring with other favourable features, such as higher enzyme activity and growth rate that might reduce manufacturing costs. All the novel strains will be screened in food production trials in collaboration with food industry partners, with taster panels used to test and confirm the appeal of the new strains and related food products.
Organisations
- University of Nottingham (Lead Research Organisation)
- New Food Innovation (Collaboration)
- Moydens Hand Made Cheese (Collaboration)
- HARPER ADAMS UNIVERSITY (Collaboration)
- J K M Foods Ltd (Collaboration)
- Highland Fine Cheeses (United Kingdom) (Collaboration)
- West Highland Dairy (Collaboration)
- Cropwell Bishop Creamery (Collaboration)
People |
ORCID iD |
| Paul Dyer (Principal Investigator) |
Publications
Cleere MM
(2024)
New colours for old in the blue-cheese fungus Penicillium roqueforti.
in NPJ science of food
Dyer PS
(2017)
Sex and the Imperfect Fungi.
in Microbiology spectrum
Dyer PS
(2018)
The Oxford Textbook of Medical Mycology
Ojeda-López M
(2018)
Evolution of asexual and sexual reproduction in the aspergilli.
in Studies in mycology
| Description | Through research funded in this award we were able to complete key aspects of work associated with the development and screeing of new strains of the fungus Penicillium roqueforti for use in the food industry. As a result a series of potential new strains, derived from the sexual crossing technology developed under previous BBSRC work, were tested for characteristics such as flavour, mycotoxin content, and growth rate. The best new strains were then used in cheese production trials and were subject to blind taste trials. These revealed at least 6 new strains that scored very favourably and have been taken forward for commercial exploitation. |
| Exploitation Route | The strains developed under the work have been patent registered by the University of Nottingham. A start-up company (Myconeos Ltd) was then launched in summer 2018 to commercially produce and market the novel strains, under licence from the University of Nottingham. |
| Sectors | Agriculture Food and Drink Retail |
| Description | As explained elsewhere in the submission, work completed in this research award has led to the identification of a series of novel fungal strains that show great promise for use in the commercial food/dairy sector for production of blue cheeses with improved flavours over those currently available. Linked to this, a start-up company Myconeos (https://myconeos.com/ and https://www.linkedin.com/company/myconeos/) has been formed, with the remit to produce, market and further develop the moulds using the technology developed under the previous BBSRC research. The company was registered in summer 2018 and has already begun to have economic impact with the establisment of laboratories in Biocity, Nottingham and employment of 4 FTE posts (moved in Feb 2020). Myconeos has also identified a commercial distributor, JKM Foods (http://www.jkm-foods.com/), for the novel strains who is an existing major UK supplier. An international distributor and Toll manufacturer, SACCO in Ital,y has now been established. The comnpany has gained HACCP and SALSA food production approval and commercial strain production and sale of strains has now begun as of March 2022, delayed from the original planned start date due to covid19 disruption. The largest blue cheese producer in Scotland, Highland Fine Cheese, is now using outr strains (https://www.myconeos.com/news/dp205-blue-cheese-soft-except-stilton-highland-fine-cheeses-ltd-3-2sjb7-zm5ec) The company has now registered a number of sales to UK producers, and has set up an agreement with a European partner (SACCO) for EU production and sales. The company was also successful in gaining two Innovate UK grants based on the previous BBSRC project work. The company was also successful in raising substantial venture company capital in Autumn 2022 as at: https://www.linkedin.com/company/myconeos/. The company has now expanded to 6 employees. |
| First Year Of Impact | 2018 |
| Sector | Agriculture, Food and Drink,Retail |
| Impact Types | Economic Policy & public services |
| Description | Presented at House of Commons Parliamentary Science, Innovation and Technology committe on harnessing power of fungi |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| URL | https://committees.parliament.uk/event/20606/formal-meeting-oral-evidence-session/ |
| Description | Agri-Food Technology Seeding Catalyst |
| Amount | £24,500 (GBP) |
| Funding ID | RR3611 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2017 |
| End | 02/2018 |
| Description | British Mycological Society Summer Studentship Scheme |
| Amount | £2,250 (GBP) |
| Organisation | British Mycological Society |
| Sector | Charity/Non Profit |
| Country | United Kingdom |
| Start | 05/2017 |
| End | 08/2018 |
| Description | Developing new strains of Penicillium roqueforti with novel characteristics for blue cheese production; Faculty REF Impact Case |
| Amount | £19,950 (GBP) |
| Funding ID | A7R526 |
| Organisation | University of Nottingham |
| Sector | Academic/University |
| Country | United Kingdom |
| Start | 03/2019 |
| End | 07/2019 |
| Description | Development of novel Penicillium camemberti strains for optimised white rind cheese production |
| Amount | £199,799 (GBP) |
| Funding ID | Myconeos |
| Organisation | Innovate UK |
| Sector | Public |
| Country | United Kingdom |
| Start | 05/2021 |
| End | 12/2022 |
| Description | Development of novel Penicillium strains optimised for mould-ripened plant-based cheese manufacturing |
| Amount | £282,568 (GBP) |
| Organisation | Innovate UK |
| Sector | Public |
| Country | United Kingdom |
| Start | 06/2023 |
| End | 12/2024 |
| Description | Seeding Catalyst Award |
| Amount | £25,000 (GBP) |
| Funding ID | BB/SCA/Nottingham/17 |
| Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
| Sector | Public |
| Country | United Kingdom |
| Start | 09/2017 |
| End | 02/2018 |
| Title | Novel method for screening of volatile flavour production |
| Description | Designed new protocols for incubation of the fungus Penicillium roqueforti in an artifical milk model system to allow assessment of production of flavour volatiles linked to taste. |
| Type Of Material | Technology assay or reagent |
| Provided To Others? | No |
| Impact | The novel method has been found to be more reliable and quicker than an exisiting published method. Work has been statistically validated. |
| Description | Industrial and academic collaborations to test and manufacture novel fungal strains |
| Organisation | Cropwell Bishop Creamery |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Maintained and built on previous contacts made on previous BBSRC Follow-on-Fund work with the first four industrial partners concerning opportunities offered by the novel fungal strains for the food industry. Specifically, we generated novel strains and produced this as commercial inoculum which we supplied to the Highland Fine Cheese and Cropwell Bishop Dairy for trial cheese production, in liaison with New Food Innovation. In the current project we then expanded our commercial contacts to include Moydens Hand Made Cheeses and academic staff at Harper Adams College with specialist knowledge of the blue cheese sector. We then generated further novel strains and produced this as commercial inoculum which we supplied to Moydens Cheeses for small-scale cheess production trials. |
| Collaborator Contribution | All partners remained very enthusiastic to assess the novel fungal strains and offered to help in small-scale production production trials, assess commercial potential, help with taste trials, and provide feedback on the utility of the novel strains. Specfically (work still ongoing): (1) Highland Fine Cheese. This partner has so far very kindly undertaken 8 full-scale cheese trials using either the novel strains we had produced or control commercial strains, at no cost. This has involved significant goods-in-kind contribution due to labour, materials, and storage costs. The partner then helped with taste trials of the cheese. The partner has recently committed to large-scale production trials as goods-in kind free contribution. (2) West Highland Dairy. This partner has so far very kindly provided expertise in taste trials of the cheese produced by Highland Fine Cheese, drawing on 30 yeasr experience in the market. This involved a fair goods-in-kind contribution as no charge was made for the taste trials and time involved, only travel costs were re-imbursed. (3) Cropwell Bishop Creamery. The partner has so far assisted in the small-scale production of 20 cheeses using novel and control strains. This involved providing personnel for two days to advise on specific stages of cheese production and jointly make the cheeses with NFI and University of Nottingham staff. (4) A new partnership was established with the Artesan cheese producer Moydens Cheeses. This partner has contributed in two ways. Has assisted with storage and maturation of a set of novel cheeses produced with partner (3). Has subsequently giving help with cheese taste trials, drawing on expertise in the market place. (5) New Food Innovation. Have continued to liaise between cheese producers and University partner to ensure success of the project, and have also opened talks with Supermarket representatives about possible commercial sales of the final cheese products. (6) Members of the academic staff at Harper Adams College have provided insights from their knowledge of the UK blue-cheese market and beyond, to assist with commercialisation of the work. They have also provided help with taste trials, given their role as tasting judging in national cheese contests. |
| Impact | (1) A series of cheese production trials have been performed with a sub-set of novel fungal strains previously identified. This allowed subsequent cheese taste trials, and the identfiication so far of six novel strains for commercial application. Excitingly, these scored better than current blue cheese production strains. (2) Discussions are underway with commercial partners to form a Technology Translational Partnership to produce and with JKM Foods to market the novel strains commercially. |
| Start Year | 2014 |
| Description | Industrial and academic collaborations to test and manufacture novel fungal strains |
| Organisation | Harper Adams University |
| Country | United Kingdom |
| Sector | Academic/University |
| PI Contribution | Maintained and built on previous contacts made on previous BBSRC Follow-on-Fund work with the first four industrial partners concerning opportunities offered by the novel fungal strains for the food industry. Specifically, we generated novel strains and produced this as commercial inoculum which we supplied to the Highland Fine Cheese and Cropwell Bishop Dairy for trial cheese production, in liaison with New Food Innovation. In the current project we then expanded our commercial contacts to include Moydens Hand Made Cheeses and academic staff at Harper Adams College with specialist knowledge of the blue cheese sector. We then generated further novel strains and produced this as commercial inoculum which we supplied to Moydens Cheeses for small-scale cheess production trials. |
| Collaborator Contribution | All partners remained very enthusiastic to assess the novel fungal strains and offered to help in small-scale production production trials, assess commercial potential, help with taste trials, and provide feedback on the utility of the novel strains. Specfically (work still ongoing): (1) Highland Fine Cheese. This partner has so far very kindly undertaken 8 full-scale cheese trials using either the novel strains we had produced or control commercial strains, at no cost. This has involved significant goods-in-kind contribution due to labour, materials, and storage costs. The partner then helped with taste trials of the cheese. The partner has recently committed to large-scale production trials as goods-in kind free contribution. (2) West Highland Dairy. This partner has so far very kindly provided expertise in taste trials of the cheese produced by Highland Fine Cheese, drawing on 30 yeasr experience in the market. This involved a fair goods-in-kind contribution as no charge was made for the taste trials and time involved, only travel costs were re-imbursed. (3) Cropwell Bishop Creamery. The partner has so far assisted in the small-scale production of 20 cheeses using novel and control strains. This involved providing personnel for two days to advise on specific stages of cheese production and jointly make the cheeses with NFI and University of Nottingham staff. (4) A new partnership was established with the Artesan cheese producer Moydens Cheeses. This partner has contributed in two ways. Has assisted with storage and maturation of a set of novel cheeses produced with partner (3). Has subsequently giving help with cheese taste trials, drawing on expertise in the market place. (5) New Food Innovation. Have continued to liaise between cheese producers and University partner to ensure success of the project, and have also opened talks with Supermarket representatives about possible commercial sales of the final cheese products. (6) Members of the academic staff at Harper Adams College have provided insights from their knowledge of the UK blue-cheese market and beyond, to assist with commercialisation of the work. They have also provided help with taste trials, given their role as tasting judging in national cheese contests. |
| Impact | (1) A series of cheese production trials have been performed with a sub-set of novel fungal strains previously identified. This allowed subsequent cheese taste trials, and the identfiication so far of six novel strains for commercial application. Excitingly, these scored better than current blue cheese production strains. (2) Discussions are underway with commercial partners to form a Technology Translational Partnership to produce and with JKM Foods to market the novel strains commercially. |
| Start Year | 2014 |
| Description | Industrial and academic collaborations to test and manufacture novel fungal strains |
| Organisation | Highland Fine Cheeses |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Maintained and built on previous contacts made on previous BBSRC Follow-on-Fund work with the first four industrial partners concerning opportunities offered by the novel fungal strains for the food industry. Specifically, we generated novel strains and produced this as commercial inoculum which we supplied to the Highland Fine Cheese and Cropwell Bishop Dairy for trial cheese production, in liaison with New Food Innovation. In the current project we then expanded our commercial contacts to include Moydens Hand Made Cheeses and academic staff at Harper Adams College with specialist knowledge of the blue cheese sector. We then generated further novel strains and produced this as commercial inoculum which we supplied to Moydens Cheeses for small-scale cheess production trials. |
| Collaborator Contribution | All partners remained very enthusiastic to assess the novel fungal strains and offered to help in small-scale production production trials, assess commercial potential, help with taste trials, and provide feedback on the utility of the novel strains. Specfically (work still ongoing): (1) Highland Fine Cheese. This partner has so far very kindly undertaken 8 full-scale cheese trials using either the novel strains we had produced or control commercial strains, at no cost. This has involved significant goods-in-kind contribution due to labour, materials, and storage costs. The partner then helped with taste trials of the cheese. The partner has recently committed to large-scale production trials as goods-in kind free contribution. (2) West Highland Dairy. This partner has so far very kindly provided expertise in taste trials of the cheese produced by Highland Fine Cheese, drawing on 30 yeasr experience in the market. This involved a fair goods-in-kind contribution as no charge was made for the taste trials and time involved, only travel costs were re-imbursed. (3) Cropwell Bishop Creamery. The partner has so far assisted in the small-scale production of 20 cheeses using novel and control strains. This involved providing personnel for two days to advise on specific stages of cheese production and jointly make the cheeses with NFI and University of Nottingham staff. (4) A new partnership was established with the Artesan cheese producer Moydens Cheeses. This partner has contributed in two ways. Has assisted with storage and maturation of a set of novel cheeses produced with partner (3). Has subsequently giving help with cheese taste trials, drawing on expertise in the market place. (5) New Food Innovation. Have continued to liaise between cheese producers and University partner to ensure success of the project, and have also opened talks with Supermarket representatives about possible commercial sales of the final cheese products. (6) Members of the academic staff at Harper Adams College have provided insights from their knowledge of the UK blue-cheese market and beyond, to assist with commercialisation of the work. They have also provided help with taste trials, given their role as tasting judging in national cheese contests. |
| Impact | (1) A series of cheese production trials have been performed with a sub-set of novel fungal strains previously identified. This allowed subsequent cheese taste trials, and the identfiication so far of six novel strains for commercial application. Excitingly, these scored better than current blue cheese production strains. (2) Discussions are underway with commercial partners to form a Technology Translational Partnership to produce and with JKM Foods to market the novel strains commercially. |
| Start Year | 2014 |
| Description | Industrial and academic collaborations to test and manufacture novel fungal strains |
| Organisation | J K M Foods Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Maintained and built on previous contacts made on previous BBSRC Follow-on-Fund work with the first four industrial partners concerning opportunities offered by the novel fungal strains for the food industry. Specifically, we generated novel strains and produced this as commercial inoculum which we supplied to the Highland Fine Cheese and Cropwell Bishop Dairy for trial cheese production, in liaison with New Food Innovation. In the current project we then expanded our commercial contacts to include Moydens Hand Made Cheeses and academic staff at Harper Adams College with specialist knowledge of the blue cheese sector. We then generated further novel strains and produced this as commercial inoculum which we supplied to Moydens Cheeses for small-scale cheess production trials. |
| Collaborator Contribution | All partners remained very enthusiastic to assess the novel fungal strains and offered to help in small-scale production production trials, assess commercial potential, help with taste trials, and provide feedback on the utility of the novel strains. Specfically (work still ongoing): (1) Highland Fine Cheese. This partner has so far very kindly undertaken 8 full-scale cheese trials using either the novel strains we had produced or control commercial strains, at no cost. This has involved significant goods-in-kind contribution due to labour, materials, and storage costs. The partner then helped with taste trials of the cheese. The partner has recently committed to large-scale production trials as goods-in kind free contribution. (2) West Highland Dairy. This partner has so far very kindly provided expertise in taste trials of the cheese produced by Highland Fine Cheese, drawing on 30 yeasr experience in the market. This involved a fair goods-in-kind contribution as no charge was made for the taste trials and time involved, only travel costs were re-imbursed. (3) Cropwell Bishop Creamery. The partner has so far assisted in the small-scale production of 20 cheeses using novel and control strains. This involved providing personnel for two days to advise on specific stages of cheese production and jointly make the cheeses with NFI and University of Nottingham staff. (4) A new partnership was established with the Artesan cheese producer Moydens Cheeses. This partner has contributed in two ways. Has assisted with storage and maturation of a set of novel cheeses produced with partner (3). Has subsequently giving help with cheese taste trials, drawing on expertise in the market place. (5) New Food Innovation. Have continued to liaise between cheese producers and University partner to ensure success of the project, and have also opened talks with Supermarket representatives about possible commercial sales of the final cheese products. (6) Members of the academic staff at Harper Adams College have provided insights from their knowledge of the UK blue-cheese market and beyond, to assist with commercialisation of the work. They have also provided help with taste trials, given their role as tasting judging in national cheese contests. |
| Impact | (1) A series of cheese production trials have been performed with a sub-set of novel fungal strains previously identified. This allowed subsequent cheese taste trials, and the identfiication so far of six novel strains for commercial application. Excitingly, these scored better than current blue cheese production strains. (2) Discussions are underway with commercial partners to form a Technology Translational Partnership to produce and with JKM Foods to market the novel strains commercially. |
| Start Year | 2014 |
| Description | Industrial and academic collaborations to test and manufacture novel fungal strains |
| Organisation | Moydens Hand Made Cheese |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | Maintained and built on previous contacts made on previous BBSRC Follow-on-Fund work with the first four industrial partners concerning opportunities offered by the novel fungal strains for the food industry. Specifically, we generated novel strains and produced this as commercial inoculum which we supplied to the Highland Fine Cheese and Cropwell Bishop Dairy for trial cheese production, in liaison with New Food Innovation. In the current project we then expanded our commercial contacts to include Moydens Hand Made Cheeses and academic staff at Harper Adams College with specialist knowledge of the blue cheese sector. We then generated further novel strains and produced this as commercial inoculum which we supplied to Moydens Cheeses for small-scale cheess production trials. |
| Collaborator Contribution | All partners remained very enthusiastic to assess the novel fungal strains and offered to help in small-scale production production trials, assess commercial potential, help with taste trials, and provide feedback on the utility of the novel strains. Specfically (work still ongoing): (1) Highland Fine Cheese. This partner has so far very kindly undertaken 8 full-scale cheese trials using either the novel strains we had produced or control commercial strains, at no cost. This has involved significant goods-in-kind contribution due to labour, materials, and storage costs. The partner then helped with taste trials of the cheese. The partner has recently committed to large-scale production trials as goods-in kind free contribution. (2) West Highland Dairy. This partner has so far very kindly provided expertise in taste trials of the cheese produced by Highland Fine Cheese, drawing on 30 yeasr experience in the market. This involved a fair goods-in-kind contribution as no charge was made for the taste trials and time involved, only travel costs were re-imbursed. (3) Cropwell Bishop Creamery. The partner has so far assisted in the small-scale production of 20 cheeses using novel and control strains. This involved providing personnel for two days to advise on specific stages of cheese production and jointly make the cheeses with NFI and University of Nottingham staff. (4) A new partnership was established with the Artesan cheese producer Moydens Cheeses. This partner has contributed in two ways. Has assisted with storage and maturation of a set of novel cheeses produced with partner (3). Has subsequently giving help with cheese taste trials, drawing on expertise in the market place. (5) New Food Innovation. Have continued to liaise between cheese producers and University partner to ensure success of the project, and have also opened talks with Supermarket representatives about possible commercial sales of the final cheese products. (6) Members of the academic staff at Harper Adams College have provided insights from their knowledge of the UK blue-cheese market and beyond, to assist with commercialisation of the work. They have also provided help with taste trials, given their role as tasting judging in national cheese contests. |
| Impact | (1) A series of cheese production trials have been performed with a sub-set of novel fungal strains previously identified. This allowed subsequent cheese taste trials, and the identfiication so far of six novel strains for commercial application. Excitingly, these scored better than current blue cheese production strains. (2) Discussions are underway with commercial partners to form a Technology Translational Partnership to produce and with JKM Foods to market the novel strains commercially. |
| Start Year | 2014 |
| Description | Industrial and academic collaborations to test and manufacture novel fungal strains |
| Organisation | New Food Innovation |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Maintained and built on previous contacts made on previous BBSRC Follow-on-Fund work with the first four industrial partners concerning opportunities offered by the novel fungal strains for the food industry. Specifically, we generated novel strains and produced this as commercial inoculum which we supplied to the Highland Fine Cheese and Cropwell Bishop Dairy for trial cheese production, in liaison with New Food Innovation. In the current project we then expanded our commercial contacts to include Moydens Hand Made Cheeses and academic staff at Harper Adams College with specialist knowledge of the blue cheese sector. We then generated further novel strains and produced this as commercial inoculum which we supplied to Moydens Cheeses for small-scale cheess production trials. |
| Collaborator Contribution | All partners remained very enthusiastic to assess the novel fungal strains and offered to help in small-scale production production trials, assess commercial potential, help with taste trials, and provide feedback on the utility of the novel strains. Specfically (work still ongoing): (1) Highland Fine Cheese. This partner has so far very kindly undertaken 8 full-scale cheese trials using either the novel strains we had produced or control commercial strains, at no cost. This has involved significant goods-in-kind contribution due to labour, materials, and storage costs. The partner then helped with taste trials of the cheese. The partner has recently committed to large-scale production trials as goods-in kind free contribution. (2) West Highland Dairy. This partner has so far very kindly provided expertise in taste trials of the cheese produced by Highland Fine Cheese, drawing on 30 yeasr experience in the market. This involved a fair goods-in-kind contribution as no charge was made for the taste trials and time involved, only travel costs were re-imbursed. (3) Cropwell Bishop Creamery. The partner has so far assisted in the small-scale production of 20 cheeses using novel and control strains. This involved providing personnel for two days to advise on specific stages of cheese production and jointly make the cheeses with NFI and University of Nottingham staff. (4) A new partnership was established with the Artesan cheese producer Moydens Cheeses. This partner has contributed in two ways. Has assisted with storage and maturation of a set of novel cheeses produced with partner (3). Has subsequently giving help with cheese taste trials, drawing on expertise in the market place. (5) New Food Innovation. Have continued to liaise between cheese producers and University partner to ensure success of the project, and have also opened talks with Supermarket representatives about possible commercial sales of the final cheese products. (6) Members of the academic staff at Harper Adams College have provided insights from their knowledge of the UK blue-cheese market and beyond, to assist with commercialisation of the work. They have also provided help with taste trials, given their role as tasting judging in national cheese contests. |
| Impact | (1) A series of cheese production trials have been performed with a sub-set of novel fungal strains previously identified. This allowed subsequent cheese taste trials, and the identfiication so far of six novel strains for commercial application. Excitingly, these scored better than current blue cheese production strains. (2) Discussions are underway with commercial partners to form a Technology Translational Partnership to produce and with JKM Foods to market the novel strains commercially. |
| Start Year | 2014 |
| Description | Industrial and academic collaborations to test and manufacture novel fungal strains |
| Organisation | West Highland Dairy |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | Maintained and built on previous contacts made on previous BBSRC Follow-on-Fund work with the first four industrial partners concerning opportunities offered by the novel fungal strains for the food industry. Specifically, we generated novel strains and produced this as commercial inoculum which we supplied to the Highland Fine Cheese and Cropwell Bishop Dairy for trial cheese production, in liaison with New Food Innovation. In the current project we then expanded our commercial contacts to include Moydens Hand Made Cheeses and academic staff at Harper Adams College with specialist knowledge of the blue cheese sector. We then generated further novel strains and produced this as commercial inoculum which we supplied to Moydens Cheeses for small-scale cheess production trials. |
| Collaborator Contribution | All partners remained very enthusiastic to assess the novel fungal strains and offered to help in small-scale production production trials, assess commercial potential, help with taste trials, and provide feedback on the utility of the novel strains. Specfically (work still ongoing): (1) Highland Fine Cheese. This partner has so far very kindly undertaken 8 full-scale cheese trials using either the novel strains we had produced or control commercial strains, at no cost. This has involved significant goods-in-kind contribution due to labour, materials, and storage costs. The partner then helped with taste trials of the cheese. The partner has recently committed to large-scale production trials as goods-in kind free contribution. (2) West Highland Dairy. This partner has so far very kindly provided expertise in taste trials of the cheese produced by Highland Fine Cheese, drawing on 30 yeasr experience in the market. This involved a fair goods-in-kind contribution as no charge was made for the taste trials and time involved, only travel costs were re-imbursed. (3) Cropwell Bishop Creamery. The partner has so far assisted in the small-scale production of 20 cheeses using novel and control strains. This involved providing personnel for two days to advise on specific stages of cheese production and jointly make the cheeses with NFI and University of Nottingham staff. (4) A new partnership was established with the Artesan cheese producer Moydens Cheeses. This partner has contributed in two ways. Has assisted with storage and maturation of a set of novel cheeses produced with partner (3). Has subsequently giving help with cheese taste trials, drawing on expertise in the market place. (5) New Food Innovation. Have continued to liaise between cheese producers and University partner to ensure success of the project, and have also opened talks with Supermarket representatives about possible commercial sales of the final cheese products. (6) Members of the academic staff at Harper Adams College have provided insights from their knowledge of the UK blue-cheese market and beyond, to assist with commercialisation of the work. They have also provided help with taste trials, given their role as tasting judging in national cheese contests. |
| Impact | (1) A series of cheese production trials have been performed with a sub-set of novel fungal strains previously identified. This allowed subsequent cheese taste trials, and the identfiication so far of six novel strains for commercial application. Excitingly, these scored better than current blue cheese production strains. (2) Discussions are underway with commercial partners to form a Technology Translational Partnership to produce and with JKM Foods to market the novel strains commercially. |
| Start Year | 2014 |
| Title | FUNGAL STRAINS, PRODUCTION AND USES THEREOF |
| Description | Patent claims development of four novel strains of the fungus Penicillium roqueforti for use in cheese and other food production. Also the methods to develop the new strains via sexual crossing and UV methodology. Also given PO code P3495GB00. |
| IP Reference | 1905360.2 |
| Protection | Patent application published |
| Year Protection Granted | 2019 |
| Licensed | Yes |
| Impact | Strains developed have been licenced to start-up company Myconeos for commercial exploitation |
| Title | Novel Fungal Strains for Cheese |
| Description | A patent application was submitted to the UK patent office on 17th November 2015 entitled "Novel Fungal Strains for Cheese". The patent related to the invention of novel Penicillium strains, the production of novel Penicillium strains, and the use of novel Penicillium strains, in particular in the production of cheese. The application covered 22 pages including text and supporting scientific data. The patent had two main claims: (1) The invention provides a method of producing strains of Penicillium by sexual reproduction. Specific methodology relating to sexual crossing methods was claimed, and the outcome that preferably the strain produced by sexual reproduction has a novel flavour profile; preferably this flavour profile is different to that of either parent used in the sexual cross. Biochemical methods to distinguish the novel strains were described. Strains produced by the crossing method might be used in the production of foodstuffs and cheese in particular. Alos the production of other useful metabolites wuth possible health beneficial properties, lower mycotoxin content and altered enzymen activity. (2) A method of producing a novel fungal strain with change in the colour of the spores produced was also claimed, using strains derived from sexual crossing. This comprised the step of mutating the strain to a novel colour, with examples provided. |
| IP Reference | GB1520209.6 |
| Protection | Patent application published |
| Year Protection Granted | |
| Licensed | No |
| Impact | Have ongoing discussions with commercial partners about a possible spin-out company or technology translational partnership. |
| Company Name | Myconeos |
| Description | Myconeos breeds new strains of fungi for a wide range of applications including food, bio-remediation, bio-fermentation and production of enzymes and colours. |
| Year Established | 2018 |
| Impact | Myconeos has identified a commercial distributor, JKM Foods (http://www.jkm-foods.com/), for the novel strains who is an existing major UK supplier. Talks are ongoing with the DTI to establish international distributors. The company has established a production facility at Biocity, Nottingham and has gained HACCP food safety approval in Spring 2022. Commercial strain production and sales have now started as of March 2022. The company has also gained a major £200K Innovate UK grant from 2021-2022. The research work and start-up company were featured on the UKRI website and Youtube as a promotional example: https://www.youtube.com/shorts/yqi9XaaXC3U |
| Website | https://www.myconeos.com/ |
| Description | Broadcast of interview with House of Commons Parliamentary Science, Innovation and Technology Committee |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Policymakers/politicians |
| Results and Impact | Broadcast of interview with House of Commons Parliamentary Science, Innovation and Technology Committee on theme of "Harnessing the Power of Fungi". Six expert international witnesses were invited to Westminster and questioned on matters such as "Zombie apocalypse or environmental saviours?" with myself providing input on food and enviromental issues including evolution of antifungal resistance in plant and animal pathogens. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://parliamentlive.tv/event/index/91a56a91-27ee-4f7a-883a-443dd46f9bb2 |
| Description | Farmer's Market |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | Some cheeses made with the novel fungal strains were trialled at an East Midlands Farmer's Market. Members of the public and University students were invited to comment on the cheeses to provide taste trial feedback. Approximately 50-100 trialled the cheeses, with an iPad style questionnaire used to get feedback on a pre-designed taste trial sheet. Useful data was collected regarding favourable new strains. |
| Year(s) Of Engagement Activity | 2018 |
| Description | Interview on Podcast series 'Future of Food' about novel strain development including colour and sex |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Interview on Podcast series 'Future of Food' about novel strain development including colour and sex. Gave commercial opportunities to promote work and used by Myconeos spin-out company. |
| Year(s) Of Engagement Activity | 2023 |
| URL | https://rss.com/podcasts/alexcrisp-futureoffood/1325274/ |
| Description | Interview with Food Science magazine about colour strain work |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Very recent interview to present development of colour fungal strains to international audience. Both to promote work content and also aim for commercial contacts. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.foodingredientsfirst.com/videos.html |
| Description | Interview with German national radio about new colour strains |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Very recent interview on German National radio to present development of colour fungal strains to international audience. Both to promote work content and also aim for commercial contacts. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.deutschlandfunk.de/regenbogen-roquefort-mikrobiologen-entwickeln-bunte-schimmelpilzspore... |
| Description | Interview with Royal Netherlands Chemical Society about colour strain work |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Very recent 2024 interview to present development of coloiur fungal strains to international audience. Both to promote work content and also aim for commercial contacts. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.sciencelink.net/news/blue-cheese-now-comes-in-white-green-and-brown/21782.article |
| Description | Interview with Science Publication about colour strain work |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Very recent interview with Science journal to explain development of coloiur fungal strains to international audience. Both to promote work content and also aim for commercial contacts. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.science.org/content/article/tinkering-fungus-genes-can-turn-blue-cheeses-red-green-or-wh... |
| Description | Presentation at Artesan Cheese Makers Meeting hosted by Neal's Yard Cheeses, August 2018 |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | Neal's Yard organised a meeting on the 'Science of Artesan Cheese Production' attended by large, medium and small-scale cheese manufacturers in the UK and also some international attendees. The meeting lasted two days and I was invited to present a 30 minute talk on my BBSRC-funded research leading to development of novel fungal strains for blue cheese production. |
| Year(s) Of Engagement Activity | 2018 |
| URL | http://scienceofartisancheese.com/ |
| Description | Presentation to Eldrimner, Sweden Artisan Food Resource Center. |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | Presented a talk on development of new fungal food strains to the 'Eldrimner' Sweden Artisan Food Resource Center at one of their monthly onine research seminars. Audience of ca. 10-20 attendees drawn from Swedish general public plus specialist professional artesna cheese makers, plus admin and teaching staff from the Eldrimner food centre (https://www.eldrimner.com). |
| Year(s) Of Engagement Activity | 2020 |
| Description | Press release from University of Nottingham about colour strain work |
| Form Of Engagement Activity | A press release, press conference or response to a media enquiry/interview |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | Press release and interview from the University of Nottingham media team to present development of colour fungal strains to international audience. Both to promote work content and also aim for commercial contacts. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.nottingham.ac.uk/news/new-colours-of-blue-cheese |
| Description | Promotional video about research work and impact produced for UKRI home website and released on YouTube |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Media (as a channel to the public) |
| Results and Impact | UKRI produced a short promotional film about the research undertaken and the impact resulting, including launch of the start-up company Myconeos. The video is being shown on the UKRI homepage and also YouTube with so far over 7,600 views (https://www.youtube.com/watch?v=yqi9XaaXC3U) |
| Year(s) Of Engagement Activity | 2020 |
| URL | https://www.youtube.com/watch?v=yqi9XaaXC3U |
| Description | Report on BBC newsround about colour strain work |
| Form Of Engagement Activity | A broadcast e.g. TV/radio/film/podcast (other than news/press) |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Schools |
| Results and Impact | Very recent report / interview to present development of colour fungal strains to national schools audience. |
| Year(s) Of Engagement Activity | 2024 |
| URL | https://www.bbc.co.uk/newsround/68225579 |