India Partnering Award: Development and application of lactic acid bacteria as designer probiotics
Lead Research Organisation:
Quadram Institute
Department Name: Gut Microbes and Health
Abstract
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
Organisations
- Quadram Institute (Lead Research Organisation)
- Guru Nanak Dev University (Collaboration)
- Government of India (Collaboration)
- Council of Scientific and Industrial Research (Collaboration)
- National Agri-Food Biotechnology Institute (Collaboration)
- National Chemical Laboratory, Pune, India (Collaboration)
- National Chemical Laboratory (Project Partner)
- Indian Council of Agricultural Research (Project Partner)
- Central Food Technological Research Institute (Project Partner)
People |
ORCID iD |
Arjan Narbad (Principal Investigator) |
Publications
Kaur S
(2023)
Beneficial effects of GABA-producing potential probiotic Limosilactobacillus fermentum L18 of human origin on intestinal permeability and human gut microbiota
in Microbial Cell Factories
Description | The first meeting was held in India in September 2014 and plans for collaboration were agreed. Indian collaborator visited IFR and developed skills in gene knockout in Lactococcus lactis. The work is now continuing in CFTRI and is progressing well A PhD student visited QIB for 5 months between November and was trained in functional analysis of probiotics. A manuscript is has been drafted for publication. 2nd workshop of the participating partners was held in February 2018 at National Dairy Research Institute in Karnal, India where the partnership progress was discussed and further collaborations were planned. The final workshop was held in Pune in August 2019 where future collaboration plans were finalised. |
Exploitation Route | The project will provide knowledge exchange between researchers form UK and India and to develop future more substantial joint funding grants. A joint grant application for a fellowship to further develop this UK-India link has was successfully submitted and a postdoc who originally trained at NDRI will come to QIB for collaborative research to enhance the collaborations set up during this partnership. The partnership has led to further collaborations between NDRI and QIB but with another research Leaser within QIB with expertise in food colloids. The plans are to explore further funding via funding sources in India and Newton funding in UK. |
Sectors | Agriculture Food and Drink Creative Economy Healthcare Manufacturing including Industrial Biotechology Pharmaceuticals and Medical Biotechnology |
Description | The award resulted in further interactions with Indian partners that allowed 2 PhD students from Amritsar University and from ICAR institute in Delhi to undertake collaborative research at Quadram Institute Bioscience (QIB). This interaction benefited both the research of QIB in the area of probiotics and also provided valuable training to the students who have both completed their PhD qualifications and have gained permanent positions in academia. Further collaborations between QIB and Indian Institutes are planned. |
First Year Of Impact | 2023 |
Sector | Agriculture, Food and Drink |
Impact Types | Societal |
Description | Oversears DBT fellowship |
Amount | ₹2,500,000 (INR) |
Organisation | Ministry of Science and Technology India |
Department | Department of Biotechnology, India |
Sector | Public |
Country | India |
Start | 07/2018 |
End | 07/2019 |
Description | Collaboration with professor Amit Rai India |
Organisation | National Agri-Food Biotechnology Institute |
Country | India |
Sector | Public |
PI Contribution | We hosted the visit of prof Amit Rai to QIB and In March 20204 Arjan Narbad visited NABI-DTP institute and gave a presentation and discussed further collaboration. |
Collaborator Contribution | Prof Rai visited QIB in February 2024 and this resulted in further planned collaboration grant applications to extend the link between QIB and NABI-DBT institute. Joint experimental work is planned. |
Impact | Further short term funding to undertake collaboration experimental work via staff exchange from NABI to QIB. |
Start Year | 2024 |
Description | Functional analysis of probiotics |
Organisation | Guru Nanak Dev University |
Country | India |
Sector | Academic/University |
PI Contribution | Provided training to the PhD student from Guru Nanak Dev University, Sumanpreet Kaur Saini. She undertook collaborative research in QIB and acquired skills in whole genome, sequencing, bioinformatics, Tissue culture and antimicrobial and antibiofilm assays. |
Collaborator Contribution | They provided manpower, bacterial strains and background information on the strains |
Impact | Sequence data and experimental that can be published in the future |
Start Year | 2017 |
Description | Joint workshop |
Organisation | Council of Scientific and Industrial Research |
Department | Central Food Technological Research Institute |
Country | India |
Sector | Academic/University |
PI Contribution | Provided travel costs for the delegates attending the meetings and workshops. |
Collaborator Contribution | Hosted two meetings and provided free accommodation and subsistence to the delegates. |
Impact | 1. Multidisciplinary network meeting. 2..agreement on the future collaboration |
Start Year | 2014 |
Description | Joint workshop |
Organisation | National Chemical Laboratory, Pune, India |
Country | India |
Sector | Public |
PI Contribution | Dr Ramachandra Gadre attended both the kick off meeting as well as the 1st joint workshop held in CFTRI, Mysore, as well as the 2nd workshop meeting in NDRI, Karnal India |
Collaborator Contribution | Dr Gadre gave a presentation at the workshop and contributed to the planning and execution of the joint networking workshop |
Impact | Multidisciplinary network meeting with agreement on the future collaboration |
Start Year | 2014 |
Description | workshop India |
Organisation | Council of Scientific and Industrial Research |
Department | Central Food Technological Research Institute |
Country | India |
Sector | Academic/University |
PI Contribution | QI planned and organised the workshop and gave a presentation and contributed to the discussion. |
Collaborator Contribution | NDRI hosted the meeting, gave a presentation and contributed to the discussions CFTRI and NCL gave a presentation and contributed to the discussions |
Impact | 1. Multidisciplinary network meeting. 2.agreement on the future collaboration |
Start Year | 2014 |
Description | workshop India |
Organisation | Government of India |
Department | ICAR-National Dairy Research Institute |
Country | India |
Sector | Public |
PI Contribution | QI planned and organised the workshop and gave a presentation and contributed to the discussion. |
Collaborator Contribution | NDRI hosted the meeting, gave a presentation and contributed to the discussions CFTRI and NCL gave a presentation and contributed to the discussions |
Impact | 1. Multidisciplinary network meeting. 2.agreement on the future collaboration |
Start Year | 2014 |
Description | workshop India |
Organisation | National Chemical Laboratory, Pune, India |
Country | India |
Sector | Public |
PI Contribution | QI planned and organised the workshop and gave a presentation and contributed to the discussion. |
Collaborator Contribution | NDRI hosted the meeting, gave a presentation and contributed to the discussions CFTRI and NCL gave a presentation and contributed to the discussions |
Impact | 1. Multidisciplinary network meeting. 2.agreement on the future collaboration |
Start Year | 2014 |