Membrane Biophysics Platform

Lead Research Organisation: Imperial College London
Department Name: Dept of Chemistry

Abstract

The proposed Platform grant renewal is aimed at giving us the ability to capitalise upon our position as a world leading group in membrane biophysics and self-assembled amphiphilic materials, and to promote and facilitate collaborations within the currently fragmented membrane biophysics community in the UK. To achieve these aims we will form collaborative research networks with groups having complementary expertise, and encourage interconnections between external groups via a combination of 'Ideas Workshops' and IT platforms. These networks will focus upon tackling key challenges at the Life Sciences Interface requiring multi-disciplinary approaches. We will support targeted short-term personnel exchange with a view to effecting knowledge transfer, proof-of-concept experiments and research training. Within this framework we will invite key collaborators as academic visitors and to present seminar series within our Department. We also wish to continue to facilitate exploitation of our specialised facilities by the wider research community.In addition to building upon the successes of our original objectives by studying the phase behaviour of novel amphiphiles and complex lipid mixtures, and the development of millisecond and microsceond pressure-jump synchrotron X-ray studies of lyotropic transitions, we also plan to develop the following areas of research within the renewed Platform grant, which we have identified as timely and important challenges at the Life/Physical Sciences interface:i) Understanding Membrane Asymmetry;ii) Protein Control of Lipid Membrane Morphology;iv) Regulation of Lipid Biosynthetic Pathways.iv) Lipid Mesophase Engineering Rules for Biomedical Imaging Applications.

Publications

10 25 50

publication icon
Barriga HM (2015) Pressure-temperature phase behavior of mixtures of natural sphingomyelin and ceramide extracts. in Langmuir : the ACS journal of surfaces and colloids

 
Description A selection of Key Findings from our Platform grant is as follows:
a) We have demonstrated that lipid membranes can act as information pathways between proteins, without the need for direct protein-protein contact;
b) We have found that lipid membrane curvature is induced by distearoyl phosphatidylinositol 4-phosphate;
c) We have characterised the pressure - temperature phase behaviour of natural sphingomyelin extracts, and found evidence for non-lamellar phases;
d) We have characterised the thermotropic and lyotropic liquid crystalline phase behaviour of a novel series of Guerbet branched-chain ß-D-glucosides, and have found that they form a variety of inverse cubic and inverse hexagonal phases;
e) We discovered a novel lyotropic two-dimensional inverse ribbon phase in a branched-chain polyoxyethylene surfactant system, and demonstrated an unusual effect of hydrostatic pressure on the lattice parameters, with one increasing, and the other decreasing, with increasing pressure;
f) We showed that we can produce ordered nanostructured amphiphile self-assembly materials from nonionic unsaturated monoethanolamide lipids in water;
g) We studied the effect of hydrostatic pressure effects on the inverse micellar Fd3m cubic phase formed by a binary lipid mixture, and found that the lattice parameter is independent of pressure, but above a threshold pressure the lipids separate into two different liquid crystal phases;
h) We developed a quantitative model for the kinetics of lyotropic phase transitions involving changes in monolayer curvature;
i) We showed that certain aqueous buffers may adversely affect the phase behaviour of model lipid membranes;
j) We have a developed a new model for how cationic drugs can interact with lipid membranes;
k) We carried out molecular dynamics simulations of liquid condensed to liquid expanded transitions in DPPC monolayers;
l) We observed the formation of an inverse hexagonal phase in DNA Lipoplexes by molecular dynamics simulations;
m) We developed a microfluidic approach for high-throughput droplet interface bilayer (DIB) formation;
n) We developed a microfluidic antibody capture chip with TIRF detection as a first step towards practical single cell proteomics.
Exploitation Route Researchers in the fields of membrane biophysics and soft matter self-assembly can learn guiding principles from our work, and industrial scientists in the healthcare, pharma and personal products sectors can use our findings in the development of novel formulations.
Sectors Agriculture, Food and Drink,Chemicals,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology

 
Description Consultancy: Lipids & Membrane Biophysics, 161 Journal Issue. Discussion summary and research papers, in physical chemistry, chemical physics and biophysical chemistry. Grant: Contributions to Industry/NHS etc through Teaching/Training £2.5M Marie Curie Innovative Doctoral Programme (IDP) in collaboration with Syngenta (13 three year PhD studentships). Invited Article: RSC Journal Analyst-Special Issue Invitation to submit article to special issue of the RSC Jourmal Analyst entitled Emerging Investigators. Its a themed issue "to highlight some of the outstanding young analytical scientists of today". Invited Article: SDM Droplet Part III Invitation to submit paper to 10th anniversary edition of "Lab On the Chip".
First Year Of Impact 2009
Sector Chemicals,Healthcare,Pharmaceuticals and Medical Biotechnology
Impact Types Cultural

 
Description Artificial hair constructs (Proctor and Gamble)
Amount £85,000 (GBP)
Organisation Procter & Gamble 
Sector Private
Country United States
Start  
 
Description Artificial hair constructs (Proctor and Gamble)
Amount £85,000 (GBP)
Organisation Procter & Gamble 
Sector Private
Country United States
Start  
 
Description Beamtime award SC2800, 3 days, Composition effects on a novel 3-D hexagonal lyotropic lipid phase and its phase transitions
Amount £30,000 (GBP)
Organisation European Synchrotron Radiation Facility 
Sector Academic/University
Country European Union (EU)
Start  
 
Description CAPITALs Programme grant, EP/J017566/1
Amount £5,900,000 (GBP)
Funding ID EP/J017566/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start 06/2012 
End 05/2017
 
Description CASE studentship
Amount £80,000 (GBP)
Organisation Procter & Gamble 
Sector Private
Country United States
Start  
 
Description Creativity@home-Novel Tools for Single Cell Manipulation
Amount £101,750 (GBP)
Funding ID EP/I031561/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description EU Multi-ITN: 'Smart Nano-objects for Alteration of Lipid Bilayers' (Project acronym: SNAL);
Amount £250,000 (GBP)
Funding ID 608184 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 04/2014 
End 03/2018
 
Description Elements of a Vesicle Machine
Amount £201,409 (GBP)
Funding ID EP/H024425/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Frontier Manufacturing: Scaling up synthetic biology
Amount £5,158,504 (GBP)
Funding ID EP/K038648/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Initial Training Networks grant for Next Generation AgriChem.
Amount £2,500,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Institute of Chemical Biology, Centre for Doctoral Training
Amount £1,000,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Membrane Translocation Initiative
Amount £115,000 (GBP)
Organisation Procter & Gamble 
Sector Private
Country United States
Start  
 
Description Membrane Translocation Initiative
Amount £115,000 (GBP)
Organisation Procter & Gamble 
Sector Private
Country United States
Start  
 
Description Membrane proteins and immune evasion, BBSRC (DTP)
Amount £90,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2013 
End 09/2017
 
Description Molecular imaging using ultrasound
Amount £716,105 (GBP)
Funding ID EP/G038163/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Next Generation Analytical Tools: Application to Protein Oxidations that affect Human Health and Wellbeing, EP/I017887/1
Amount £3,885,167 (GBP)
Funding ID EP/I017887/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Nuffield Bursary Scheme
Amount £2,000 (GBP)
Organisation Nuffield Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Optical Control of Emulsion Drops for Nanofluidics and Microfabrication
Amount £505,226 (GBP)
Funding ID EP/I013342/1 
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Pathways to Impact Funding
Amount £74,429 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Pathways to Impact: Hybrid Self-sustaining Microscale Machinery, IC/EPSRC
Amount £75,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Pathways to Impact: New Analytical Tools for Personalized Healthcare and Portable Separation Science, IC/EPSRC
Amount £75,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start 06/2010 
End 06/2011
 
Description PhD Studentship (Membrane Protein Folding), Pfizer plc
Amount £46,000 (GBP)
Organisation Pfizer Ltd 
Sector Private
Country United Kingdom
Start  
 
Description PhD Studentship (Membrane Protein Folding), Pfizer plc
Amount £46,000 (GBP)
Organisation Pfizer Ltd 
Sector Private
Country United Kingdom
Start  
 
Description Studies of membrane mediated protein-protein communication, BBSRC (DTP)
Amount £90,000 (GBP)
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 10/2013 
End 09/2017
 
Description Synchr beam time , SC 3134
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time , SC 3134
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time : Membrane homeostasis, SC 2799
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time : Membrane homeostasis, SC 2799
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time, SC 3266
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time, SC 3266
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time: 3-D hexagonal phase, SC 2800
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time: 3-D hexagonal phase, SC 2800
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time: Bridging the divide between lyotropic phase transitions in model membranes and ex-vivo systems, SC 2904
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time: Bridging the divide between lyotropic phase transitions in model membranes and ex-vivo systems, SC 2904
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time: Patterned cubics, SC 3664
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time: Patterned cubics, SC 3664
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time: Swollen cubics, SC 3495
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Synchr beam time: Swollen cubics, SC 3495
Amount £30,000 (GBP)
Organisation European Commission 
Sector Public
Country European Union (EU)
Start  
 
Description Three Studentships (Non-Specific Binding Initiative), GSK plc
Amount £133,000 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start  
 
Description Three Studentships (Non-Specific Binding Initiative), GSK plc
Amount £133,000 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start 10/2006 
End 09/2010
 
Description Tsinghua University Exchange Programme, IC/EPSRC
Amount £45,000 (GBP)
Organisation Engineering and Physical Sciences Research Council (EPSRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Two Non-Specific Binding Studentships, GSK plc
Amount £147,000 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start 10/2008 
End 09/2013
 
Description Two Non-Specific Binding Studentships, GSK plc
Amount £147,000 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start  
 
Description Scientific Collaboration 
Organisation Cancer Research UK
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Collaboration with Peter Parker on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection"
Start Year 2010
 
Description Scientific Collaboration 
Organisation Commonwealth Scientific and Industrial Research Organisation
Country Australia 
Sector Public 
PI Contribution Collaboration with Sharon M. Sagnella on "Ordered Nanostructured Amphiphile Self-Assembly Materials from Endogenous Nonionic Unsaturated Monoethanolamide Lipids in Water"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Commonwealth Scientific and Industrial Research Organisation
Country Australia 
Sector Public 
PI Contribution Collaboration with Minoo Moghaddam on "Ordered Nanostructured Amphiphile Self-Assembly Materials from Endogenous Nonionic Unsaturated Monoethanolamide Lipids in Water"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Commonwealth Scientific and Industrial Research Organisation
Country Australia 
Sector Public 
PI Contribution Collaboration with Calum J. Drummond on "Ordered Nanostructured Amphiphile Self-Assembly Materials from Endogenous Nonionic Unsaturated Monoethanolamide Lipids in Water"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Commonwealth Scientific and Industrial Research Organisation
Country Australia 
Sector Public 
PI Contribution Collaboration with Irena Krodkiewska on "Ordered Nanostructured Amphiphile Self-Assembly Materials from Endogenous Nonionic Unsaturated Monoethanolamide Lipids in Water"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Commonwealth Scientific and Industrial Research Organisation
Country Australia 
Sector Public 
PI Contribution Collaboration with Charlotte E. Conn on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides", "Ordered Nanostructured Amphiphile Self-Assembly Materials from Endogenous Nonionic Unsaturated Monoethanolamide Lipids
Start Year 2010
 
Description Scientific Collaboration 
Organisation Diamond Light Source
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Adam J Kowalski on "Complex fluids under microflow probed by SAXS: rapid microfabrication and analysis"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Diamond Light Source
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Nick J. Terrill on "Hydrostatic Pressure Effects on the Lamellar to Gyroid Cubic Phase Transition of Monolinolein at Limited Hydration", "Complex fluids under microflow probed by SAXS: rapid microfabrication and analysis"
Start Year 2011
 
Description Scientific Collaboration 
Organisation ETH Zurich
Department Department of Chemistry and Applied Biosciences
Country Switzerland 
Sector Academic/University 
PI Contribution Collaboration with Andrew J. deMello on "Novel technologies for the formation of 2-D and 3-D droplet interface bilayer networks"
Start Year 2011
 
Description Scientific Collaboration 
Organisation European Synchrotron Radiation Facility
Country European Union (EU) 
Sector Academic/University 
PI Contribution Collaboration with Michael Sztucki on "A lyotropic inverse ribbon phase in a branched-chain polyoxyethylene surfactant: pressure effects"
Start Year 2010
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Fernando Bresme on "Molecular Dynamics Simulations of Liquid Condensed to Liquid Expanded Transitions in DPPC Monolayers"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Hazel P Martin on "Complex fluids under microflow probed by SAXS: rapid microfabrication and analysis"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with David Klug on "Droplet-based compartmentalization of chemically separated components in two-dimensional separations"
Start Year 2008
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Nick Long on PET ligand synthesis
Start Year 2011
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Edward W. Tate on "Lipid membrane curvature induced by distearoyl phosphatidylinositol 4-phosphate"
Start Year 2011
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with A. D. Gee on "A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation" and "Drug interactions with lipid membranes"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Dan Davis on Membrane organisation at the synapse
Start Year 2009
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Emilie Macé on "Molecular Dynamics Simulations of Liquid Condensed to Liquid Expanded Transitions in DPPC Monolayers"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with João T Cabral on "Complex fluids under microflow probed by SAXS: rapid microfabrication and analysis"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with K. S. Elvira on "A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Hairul A.A. Hamid on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides"
Start Year 2010
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Rüdiger Woscholski on "Lipid membrane curvature induced by distearoyl phosphatidylinositol 4-phosphate", "Engineering de Novo Membrane-Mediated Protein?Protein Communication Networks"
Start Year 2011
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Joseph Kaplinsky on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection"
Start Year 2010
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Teresa Peiró-Salvador on "Buffers May Adversely Affect Model Lipid Membranes: A Cautionary Tale"
Start Year 2008
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with J. B. Edel on "A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Mark A. A. Neil on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection"
Start Year 2010
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Piers R. J. Gaffney on "Lipid membrane curvature induced by distearoyl phosphatidylinositol 4-phosphate"
Start Year 2011
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Paul French on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection"
Start Year 2010
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with B. Zhang on "Droplet-based compartmentalization of chemically separated components in two-dimensional separations"
Start Year 2008
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Andrew J. Heron on "A high pressure cell for simultaneous osmotic pressure and x-ray diffraction measurements "
Start Year 2008
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with R. T. Marszalek on "Droplet-based compartmentalization of chemically separated components in two-dimensional separations"
Start Year 2008
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Martin Buck on PspA - membrane interactions
Start Year 2010
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Doryen Bubeck on "Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59"
Start Year 2012
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Laura M. C. Barter on "Engineering de Novo Membrane-Mediated Protein?Protein Communication Networks"
Start Year 2011
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Sophia Yaliraki on Modelling membrane binding
Start Year 2012
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Paul S. Freemont on "Design of a prototype flow microreactor for synthetic biology in vitro"
Start Year 2012
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Ian Gould on Drug-lipid interactions
Start Year 2011
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Duncan Casey on "Drug interactions with lipid membranes"
Start Year 2008
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Ali Salehi-Reyhani on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection"
Start Year 2010
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with X. Z. Niu on "A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Christian R. Boehm on "Design of a prototype flow microreactor for synthetic biology in vitro"
Start Year 2012
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Paul F Luckham on "Complex fluids under microflow probed by SAXS: rapid microfabrication and analysis"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Tsing-Young Tang on "Engineering bicontinuous cubic structures at the nanoscale?the role of chain splay"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with C. E. Stanley on "A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with James A. Clarkeon on "Pressure?temperature phase behaviour of natural sphingomyelin extracts"
Start Year 2010
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Edward Burgin on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection"
Start Year 2010
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Xiaodong Zhang on PspA - membrane interactions
Start Year 2010
 
Description Scientific Collaboration 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Annela M. Seddonon "Buffers May Adversely Affect Model Lipid Membranes: A Cautionary Tale", "Drug interactions with lipid membranes", Lipid membrane curvature induced by distearoyl phosphatidylinositol 4-phosphate, "Engineering bicontin
Start Year 2008
 
Description Scientific Collaboration 
Organisation Institute of Cancer Research UK
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Keith R. Willison on "A first step towards practical single cell proteomics: a microfluidic antibody capture chip with TIRF detection"
Start Year 2010
 
Description Scientific Collaboration 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Cécile A. Dreiss on "Assembling and de-assembling micelles: competitive interactions of cyclodextrins and drugs with Pluronics"
Start Year 2008
 
Description Scientific Collaboration 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Ekene Nwabunwanne on "Assembling and de-assembling micelles: competitive interactions of cyclodextrins and drugs with Pluronics"
Start Year 2008
 
Description Scientific Collaboration 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Rong Liu on "Assembling and de-assembling micelles: competitive interactions of cyclodextrins and drugs with Pluronics"
Start Year 2008
 
Description Scientific Collaboration 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Richard A.G. Smith on "A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Max Planck Society
Department Max Planck Institute of Colloids and Interfaces
Country Germany 
Sector Academic/University 
PI Contribution Collaboration with Rumiana Dimova on Membrane fusion
Start Year 2009
 
Description Scientific Collaboration 
Organisation Polytechnic University of Valencia
Country Spain 
Sector Academic/University 
PI Contribution Collaboration with Alfonso Martínez-Felipe on "Non-symmetric liquid crystal dimer containing a carbohydrate-based moiety"
Start Year 2011
 
Description Scientific Collaboration 
Organisation Rutherford Appleton Laboratory
Country United Kingdom 
Sector Public 
PI Contribution Collaboration with Sarah E. Rogers on "Automated high pressure cell for pressure jump x-ray diffraction"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Shiraz University of Technology
Country Iran, Islamic Republic of 
Sector Academic/University 
PI Contribution Collaboration with Delara Mohammad-Aghaie on "Molecular Dynamics Simulations of Liquid Condensed to Liquid Expanded Transitions in DPPC Monolayers"
Start Year 2009
 
Description Scientific Collaboration 
Organisation Technical University of Dortmund
Country Germany 
Sector Academic/University 
PI Contribution Collaboration with Christoph Jeworrek on "Hydrostatic Pressure Effects on the Lamellar to Gyroid Cubic Phase Transition of Monolinolein at Limited Hydration"
Start Year 2011
 
Description Scientific Collaboration 
Organisation Technical University of Dortmund
Country Germany 
Sector Academic/University 
PI Contribution Collaboration with Roland Winter on "Hydrostatic Pressure Effects on the Lamellar to Gyroid Cubic Phase Transition of Monolinolein at Limited Hydration"
Start Year 2011
 
Description Scientific Collaboration 
Organisation Unilever
Department Unilever Research and Development
Country United Kingdom 
Sector Private 
PI Contribution Collaboration with Stephane Ugazio on "Factors Controlling the Stability of a Kinetically Hindered Lamellar_Lamellar Transition", "The lyotropic phase behaviour of ester quaternary surfactants"
Start Year 2008
 
Description Scientific Collaboration 
Organisation Unilever
Department Unilever Research and Development
Country United Kingdom 
Sector Private 
PI Contribution Collaboration with John Hubbard on "Factors Controlling the Stability of a Kinetically Hindered Lamellar_Lamellar Transition", "The lyotropic phase behaviour of ester quaternary surfactants"
Start Year 2008
 
Description Scientific Collaboration 
Organisation Unilever
Department Unilever Research and Development
Country United Kingdom 
Sector Private 
PI Contribution Collaboration with Laurent Soubiran on "Factors Controlling the Stability of a Kinetically Hindered Lamellar_Lamellar Transition", "The lyotropic phase behaviour of ester quaternary surfactants"
Start Year 2008
 
Description Scientific Collaboration 
Organisation University Paris Sud
Country France 
Sector Academic/University 
PI Contribution Collaboration with H. Delacroix on "Hydrostatic pressure effects on a hydrated lipid inverse micellar Fd3m cubic phase"
Start Year 2010
 
Description Scientific Collaboration 
Organisation University of Aberdeen
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Andrew G. Cook on "Non-symmetric liquid crystal dimer containing a carbohydrate-based moiety"
Start Year 2011
 
Description Scientific Collaboration 
Organisation University of Aberdeen
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Corrie T. Imrie on "Non-symmetric liquid crystal dimer containing a carbohydrate-based moiety"
Start Year 2011
 
Description Scientific Collaboration 
Organisation University of Aberdeen
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with James L. Wardell on "Non-symmetric liquid crystal dimer containing a carbohydrate-based moiety"
Start Year 2011
 
Description Scientific Collaboration 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Annela M. Seddonon "Buffers May Adversely Affect Model Lipid Membranes: A Cautionary Tale", "Drug interactions with lipid membranes", Lipid membrane curvature induced by distearoyl phosphatidylinositol 4-phosphate, "Engineering bicontin
Start Year 2008
 
Description Scientific Collaboration 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Paula J. Booth on "Engineering de Novo Membrane-Mediated Protein?Protein Communication Networks"
Start Year 2011
 
Description Scientific Collaboration 
Organisation University of Malaya
Country Malaysia 
Sector Academic/University 
PI Contribution Collaboration with N. Idayu Zahid on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides"
Start Year 2010
 
Description Scientific Collaboration 
Organisation University of Malaya
Country Malaysia 
Sector Academic/University 
PI Contribution Collaboration with Syahila Duali Hussen on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides"
Start Year 2010
 
Description Scientific Collaboration 
Organisation University of Malaya
Country Malaysia 
Sector Academic/University 
PI Contribution Collaboration with Seyed M. Mirzadeh Husseini on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides"
Start Year 2010
 
Description Scientific Collaboration 
Organisation University of Malaya
Country Malaysia 
Sector Academic/University 
PI Contribution Collaboration with Thorsten Heidelberg on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides"
Start Year 2010
 
Description Scientific Collaboration 
Organisation University of Malaya
Country Malaysia 
Sector Academic/University 
PI Contribution Collaboration with Rauzah Hashim on "Thermotropic and lyotropic liquid crystalline phases of Guerbet branched-chain -D-glucosides"
Start Year 2010
 
Description Scientific Collaboration 
Organisation University of Manchester
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Gordon J. T. Tiddy on "A lyotropic inverse ribbon phase in a branched-chain polyoxyethylene surfactant: pressure effects"
Start Year 2010
 
Description Scientific Collaboration 
Organisation University of Nottingham
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Paul O'Shea
Start Year 2009
 
Description Scientific Collaboration 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Steven Johnson on "Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59"
Start Year 2012
 
Description Scientific Collaboration 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Susan M. Lea on "Structural Basis for Recognition of the Pore-Forming Toxin Intermedilysin by Human Complement Receptor CD59"
Start Year 2012
 
Description Scientific Collaboration 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Josephine Corsi on "DNA Lipoplexes: Formation of the Inverse Hexagonal Phase Observed by Coarse-Grained Molecular Dynamics Simulation"
Start Year 2009
 
Description Scientific Collaboration 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Syma Khalid on "DNA Lipoplexes: Formation of the Inverse Hexagonal Phase Observed by Coarse-Grained Molecular Dynamics Simulation"
Start Year 2009
 
Description Scientific Collaboration 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with George S. Attard on "DNA Lipoplexes: Formation of the Inverse Hexagonal Phase Observed by Coarse-Grained Molecular Dynamics Simulation"
Start Year 2009
 
Description Scientific Collaboration 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Robert W. Hawtin on "DNA Lipoplexes: Formation of the Inverse Hexagonal Phase Observed by Coarse-Grained Molecular Dynamics Simulation"
Start Year 2009
 
Description Scientific Collaboration 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Xize Niu on "Novel technologies for the formation of 2-D and 3-D droplet interface bilayer networks"
Start Year 2011
 
Description Scientific Collaboration 
Organisation University of Warwick
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration with Nigel Burroughs on Modelling the immune synapse
Start Year 2011
 
Description Visiting Professor 
Organisation University of Malaya
Department Physics Department
Country Malaysia 
Sector Academic/University 
PI Contribution 12 lectures on ?Lyotropic Liquid Crystals and X-ray Diffraction?
Start Year 2011
 
Description CECAM Workshop 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Postgraduate students
Results and Impact Workshop entitled "Multi scale approaches to nano-structured soft matter: from amphiphiles to block copolymers".
Year(s) Of Engagement Activity 2018
 
Description Chair 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact ISIS Facility Board, STFC
Year(s) Of Engagement Activity 2015,2016
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact The Festival was formulated as a chance to bring the CDTs together and discuss the future of science and the importance of CDTs.
Year(s) Of Engagement Activity 2012
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact In collaboration with Medi-mation produced series of short movies to showcase engineering principles behind EPSRC funded work looking at the development of artificial cells.
Year(s) Of Engagement Activity 2012
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Invited talk at DSM plc in Holland on the ICB.
Year(s) Of Engagement Activity 2011
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Paper has been identified as a 'hot article' for Soft Matter.
Year(s) Of Engagement Activity 2011
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact European Network of Excellence for Biophotonics feature article on Nanoblobs.
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact RSC Chemical Biology Highlights Article.
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Editorial Board.
Year(s) Of Engagement Activity 2010
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Invited Lecture.
Year(s) Of Engagement Activity 2013
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact Invited Lecture. This represented the first joint ILL and ESRF user meeting.
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Invited Lecture. High pressure research is a fast growing discipline, yielding interesting and exciting results in many fields of science, technology and biotechnology.
Year(s) Of Engagement Activity 2011
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Organiser of Chemistry Stand at Imperial Festival. Imperial Festival is a brand new annual celebration that showcase to the public the myriad accomplishments and activities of staff and students at Imperial.
Year(s) Of Engagement Activity 2013
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Member, Editorial Board.
Year(s) Of Engagement Activity 2012
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Organiser of Chemistry Stand at Imperial Festival. Imperial Festival is a brand new annual celebration that showcase to the public the myriad accomplishments and activities of staff and students at Imperial.
Year(s) Of Engagement Activity 2012
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Invited Lecture. Symposia were showcasing various aspects of collaboration across different geographic regions or between different sectors of chemical research (industry, academia, research institutes, government laboratories). Symposia were focusing on partnerships between traditional industries and contract research organizations (CROs) or contract manufacturing organizations (CMO's). Other collaborative arrangements of interest included precompetitive industrial collaborations on enabling chemical technologies, new technologies and new strategies for facilitating effective collaborations across multiple time zones, and managing intellectual property and licensing.
Year(s) Of Engagement Activity 2010
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Member of the Editorial Board (Chemistry Subcommittee).
Year(s) Of Engagement Activity 2013
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Editorial Advisory Panel.
Year(s) Of Engagement Activity 2011
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Invited Lecture.
Year(s) Of Engagement Activity 2012
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Organised off-site visits for undergraduate students (2009). Took 3rd years to Diamond Light Source to give them experience of large scale research facilities.
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Invited Front Cover.
Year(s) Of Engagement Activity 2010
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Member of the Editorial Board of Biochimica Biophysica Acta (Jan 2000 - present).
Year(s) Of Engagement Activity Pre-2006,2006
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Member of the Editorial Advisory Board (Chemistry Subcommittee) of Imperial College Press (May 2003 - present).
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Invited Front Cover-Chem Soc Rev ( £500, cover art charge ).
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact Schools talk at Peter Symonds College.
Year(s) Of Engagement Activity 2012
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Chair of Chemistry panel June 2009 - EPSR.
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Public engagement talk.
Year(s) Of Engagement Activity 2010
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Plenary Lecture. The ESRF Users' Meeting gave ESRF Users the opportunity to discuss the most recent advances in science using synchrotron radiation and also, exceptionally this year, to participate in lively discussions about the future of ESRF and how it could be used to solve some of today's biggest challenges in science.
Year(s) Of Engagement Activity 2013
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Featured on ESRF homepage as a 'Spotlight on Science'.
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Highlight feature on International Liquid Crystal Society website (Figure provided by Gemma Shearman).
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Schools
Results and Impact Organised the London Schools Chemistry Challenge, a competition designed to commemorate the International Year of Chemistry that was open to all students studying Chemistry (GCSE or A-level) in secondary schools in Greater London. Entries could take the form of a poster, model, booklet, video presentation-the choice was left to the students. The competition was an overwhelming success with 1300 students registering to take part from 250 schools across London.
Year(s) Of Engagement Activity 2012
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Invited Lecture, Distinguished Faculty.
Year(s) Of Engagement Activity 2010
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Undergraduate students
Results and Impact Organised off-site visits for undergraduate students (2010). Took 3rd years to Diamond Light Source to give them experience of large scale research facilities.
Year(s) Of Engagement Activity 2010
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Study participants or study members
Results and Impact Industry / academia engagement talk arranged by RSC / British FCO at National Chemical Laboratories.
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Industry/Business
Results and Impact Invited talk at DSM plc to DSM Board/Research Strategy Team (on SCP project).
Year(s) Of Engagement Activity 2011
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Invited Lecture.
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Non-Executive Board Member, ICON (2005 - 2013).
Year(s) Of Engagement Activity Pre-2006,2006
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Member of the Editorial Board of Current Opinion in Colloid and Interface Science (Jan 1995 - present).
Year(s) Of Engagement Activity Pre-2006,2006
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Editorial Board of the Royal Society's Journal "Interface" (2004 - 2011).
Year(s) Of Engagement Activity Pre-2006,2006
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Invited talk at the RSC "Top of the Class".
Year(s) Of Engagement Activity 2011
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Guest Editor. Comissioned to put together a special issue on Single Cell Analysis for Biomicrofluidics (with Andrew de Mello).
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Invited Lecture: "DNA double helices recognize mutual sequence homology in a protein free environment".
Year(s) Of Engagement Activity 2009
 
Description Development of submillimetre bolometer array and wafer bonding 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Attended play on creation of mauveine and roseine and unveiled plaque at Victory PLace Primary school.
Year(s) Of Engagement Activity 2009
 
Description Invited Lecture - 18th International Biophysics Congress, Brisbane, 2rd - 7th August 2014. 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact 18th International Biophysics Congress, Brisbane, 2rd - 7th August 2014.
Year(s) Of Engagement Activity 2014
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Physical Sciences Strategic Advisory Board - EPSRC (2008-2011)
Year(s) Of Engagement Activity 2008,2009,2010,2011
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Physical Chemistry Chemical Physics (PCCP) Ownership Board - one of 2 UK representatives (2012 - )
Year(s) Of Engagement Activity 2012,2013,2014,2015,2016
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Committee member, British Biophysical Society (2001 - present)
Year(s) Of Engagement Activity Pre-2006,2006,2007,2008,
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact EPSRC Career Acceleration and Leadership Fellowships Panel (9th December 2009)
Year(s) Of Engagement Activity 2009
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Faraday Division Council Member (2009 - 2012)
Year(s) Of Engagement Activity 2009,2010,2011,2012
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact EPSRC Career Acceleration and Leadership Fellowships Panel (9th November 2010)
Year(s) Of Engagement Activity 2010
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Diamond Synchrotron Beamline I22 Working Group (June 2006 -present)
Year(s) Of Engagement Activity 2006,2007,2008,2009,2010
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact RSC Faraday Division Awards Panel for 2013
Year(s) Of Engagement Activity 2013
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Joint ISIS Instrument Beam Managemant Group member (IBM 5; Spectroscopy)
Year(s) Of Engagement Activity 2015,2016
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact EPSRC College: Structure, Bonding and Reaction Mechanism (January 2006 - present)
Year(s) Of Engagement Activity Pre-2006,2006,2007,2008,
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact American Biophysical Society
Year(s) Of Engagement Activity 2015,2016
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact EPSRC Panel: Materials (12th February 2009)
Year(s) Of Engagement Activity 2009
 
Description Member 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Member, Scientific Unions Committee of Royal Society (2004 - present)
Year(s) Of Engagement Activity Pre-2006,2006,2007,2008,
 
Description Membership of guideline committee 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Roving Panel Member, EPSRC Physical Sciences Meeting (25th - 26th Sept 2012)
Year(s) Of Engagement Activity 2012
 
Description Membership of guideline committee 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact RSC Council representing Faraday Division (7th July 2010)
Year(s) Of Engagement Activity 2010
 
Description Panel Chair 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Panel Chair for the evaluation of the Danish Centre for Insoluble Protein Structures (2009).
Year(s) Of Engagement Activity 2009
 
Description Reviewer 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Assessor of research outputs, Dept of Applied Mathematics, Australian National University, Canberra (2010)
Year(s) Of Engagement Activity 2010
 
Description Reviewer 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact External Reviewer for University of Manchester School of Chemistry REF Preparation Exercise (2012)
Year(s) Of Engagement Activity 2012
 
Description Reviewer 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Beamline ID02 Review Panel, European Synchrotron Radiation Facility (ESRF), Grenoble, 24th - 25th May 2011
Year(s) Of Engagement Activity 2011
 
Description Secretary 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact British Biophysical Society (2008 - 2011)
Year(s) Of Engagement Activity 2008,2009,2010,2011
 
Description Secretary 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact European Biophysical Societies' Association, (2013 - present)
Year(s) Of Engagement Activity 2013,2014,2015,2016