Solid-state NMR Research Service for UK Universities
Lead Research Organisation:
Durham University
Department Name: Chemistry
Abstract
Solid-state NMR is an important technique for characterising and studying solid materials whether they are homogeneous or heterogeneous, crystalline or amorphous. It can be applied across a wide-range of chemistry including novel organic, inorganic, organometallic and hybrid compounds, polymers (both natural and synthetic), fuels, pharmaceutical and excipients, composites, ceramics, catalysts, liquid crystals and biologically-based systems. This proposal is for a solid-state nuclear magnetic resonance (NMR) research service. The service will be available to members of the UK academic community and will based around a new state-of-the-art 400 MHz spectrometer. It will build upon the well-established and highly-experienced service currently running at Durham. The service will offer experiment planning and interpretation, in addition to providing high-quality spectra. It will promote the application of solid-state NMR to chemical problems and will act as a centre for practical training in solid-state NMR methodology. The EPSRC service will run in parallel to a commercial service supporting the research and development needs of industry. The case for support describes how the service will be structured, how it will operate and how much instrument time will be available to its users. It is proposed that the Service will operate for a period of five years to permit a major equipment upgrade to be carried out and its impact evaluated.
Organisations
Publications
Jones M
(2008)
Heterogeneous catalysts for the controlled ring-opening polymerisation of rac-lactide and homogeneous silsesquioxane model complexes
in Dalton Transactions
Yuan W
(2010)
High reactivity of metal-organic frameworks under grinding conditions: parallels with organic molecular materials.
in Angewandte Chemie (International ed. in English)
Ascough P
(2008)
Influence of production variables and starting material on charcoal stable isotopic and molecular characteristics
in Geochimica et Cosmochimica Acta
Robinson M
(2007)
Mesoporous aluminosilicate promoted alcoholysis of epoxides
in Tetrahedron Letters
Robinson M
(2007)
Mesoporous aluminosilicate promoted protection and deprotection of carbonyl compounds
in Tetrahedron Letters
Xia Y
(2008)
Mesoporous MCM-48 Aluminosilica Oxynitrides: Synthesis and Characterization of Bifunctional Solid Acid-Base Materials
in The Journal of Physical Chemistry C
Shiju N
(2011)
Mesoporous Silica with Site-Isolated Amine and Phosphotungstic Acid Groups: A Solid Catalyst with Tunable Antagonistic Functions for One-Pot Tandem Reactions
in Angewandte Chemie International Edition
Kennedy C
(2007)
Microfibril diameter in celery collenchyma cellulose: X-ray scattering and NMR evidence
in Cellulose
Castro M
(2010)
Molecular Modeling, Multinuclear NMR, and Diffraction Studies in the Templated Synthesis and Characterization of the Aluminophosphate Molecular Sieve STA-2
in The Journal of Physical Chemistry C
Kubczyk T
(2011)
Nanoporous aluminosilicate catalyzed Friedel-Crafts alkylation reactions of indoles with aldehydes and acetals
in Green Chemistry
Description | The Solid-State NMR service provided NMR spectra and interpretation services for users without ready access to this important, but relatively expensive, analytical technique for analysing solid materials. This work fed into a large number of papers (74 listed here) over the period. Aided by the baseline EPSRC funding, the Service ran a busy commercial operation over the funding period, supplying services to 10-15 companies per year in, for example, the petrochemical, pharmaceutical, agrichemical, polymer and defence industries. |
Exploitation Route | This is best addressed by individual users of the Service. We have indicated below the areas in which the Service had a significant impact. |
Sectors | Agriculture, Food and Drink,Chemicals,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology |
Description | EPSRC |
Amount | £668,649 (GBP) |
Funding ID | Contract 01SSN01112011 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 11/2011 |
End | 10/2016 |