Solid-state NMR Research Service for UK Universities
Lead Research Organisation:
Durham University
Department Name: Chemistry
Abstract
Solid-state NMR is an important technique for characterising and studying solid materials whether they are homogeneous or heterogeneous, crystalline or amorphous. It can be applied across a wide-range of chemistry including novel organic, inorganic, organometallic and hybrid compounds, polymers (both natural and synthetic), fuels, pharmaceutical and excipients, composites, ceramics, catalysts, liquid crystals and biologically-based systems. This proposal is for a solid-state nuclear magnetic resonance (NMR) research service. The service will be available to members of the UK academic community and will based around a new state-of-the-art 400 MHz spectrometer. It will build upon the well-established and highly-experienced service currently running at Durham. The service will offer experiment planning and interpretation, in addition to providing high-quality spectra. It will promote the application of solid-state NMR to chemical problems and will act as a centre for practical training in solid-state NMR methodology. The EPSRC service will run in parallel to a commercial service supporting the research and development needs of industry. The case for support describes how the service will be structured, how it will operate and how much instrument time will be available to its users. It is proposed that the Service will operate for a period of five years to permit a major equipment upgrade to be carried out and its impact evaluated.
Organisations
Publications
Lawrence C
(2010)
One step room temperature synthesis of ordered mesoporous silicaSBA-15 mediated by cellulose nanoparticles
in J. Mater. Chem.
Chong L
(2008)
One-pot rapid low-cost synthesis of Pd-fullerite catalysts
in Journal of Materials Chemistry
Karimi B
(2010)
Ordered mesoporous organosilica with ionic-liquid framework: an efficient and reusable support for the palladium-catalyzed Suzuki-Miyaura coupling reaction in water.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Storr TE
(2009)
Pd(0)/Cu(I)-mediated direct arylation of 2'-deoxyadenosines: mechanistic role of Cu(I) and reactivity comparisons with related purine nucleosides.
in The Journal of organic chemistry
White RJ
(2010)
Pectin-derived porous materials.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Neale PA
(2009)
pH dependence of steroid hormone--organic matter interactions at environmental concentrations.
in The Science of the total environment
Nep E
(2011)
Physicochemical characterization of grewia polysaccharide gum: Effect of drying method
in Carbohydrate Polymers
Evans I
(2008)
Polymorphism and hydrogen bonding in cinchomeronic acid: a variable temperature experimental and computational study
in CrystEngComm
White R
(2010)
Polysaccharide-Derived Carbons for Polar Analyte Separations
in Advanced Functional Materials
Description | The Solid-State NMR service provided NMR spectra and interpretation services for users without ready access to this important, but relatively expensive, analytical technique for analysing solid materials. This work fed into a large number of papers (74 listed here) over the period. Aided by the baseline EPSRC funding, the Service ran a busy commercial operation over the funding period, supplying services to 10-15 companies per year in, for example, the petrochemical, pharmaceutical, agrichemical, polymer and defence industries. |
Exploitation Route | This is best addressed by individual users of the Service. We have indicated below the areas in which the Service had a significant impact. |
Sectors | Agriculture, Food and Drink,Chemicals,Healthcare,Manufacturing, including Industrial Biotechology,Pharmaceuticals and Medical Biotechnology |
Description | EPSRC |
Amount | £668,649 (GBP) |
Funding ID | Contract 01SSN01112011 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 11/2011 |
End | 10/2016 |