Warwick Centre for Analytical Science
Lead Research Organisation:
University of Warwick
Department Name: Chemistry
Abstract
Analytical Science involves the development and application of new methods to measure the composition and structure of manufactured and natural substances of all types. The analytical sector in the UK underpins many vital industries (e.g. food, chemical, pharmaceutical, environmental, materials), is crucial to process and cost control, to product quality and competitiveness, to industrial compliance with environmental and safety legislation, and to the delivery of healthcare and justice. Crucially, progress in Analytical Science is also essential to advances in many key research areas including materials and life sciences. Modern analytical problems often require high spatial resolution in three dimensions, resulting in very large, complex data sets. Moreover, there is a need to combine information from multiple data sets of very different provenance. Recent official reviews have warned that, despite its central importance to the UK's economic and scientific competitiveness, Analytical Science in the UK suffers from low esteem and fragmentation, and lacks interdisciplinarity. The result is a shortage of analytical scientists, and an alarmingly low level of innovation compared to other countries. Research and innovation-led reinvigoration of this area is essential for the UK's economic and social well-being. The University of Warwick invests heavily in multidisciplinary research and education, and has a strong research base in Analytical Science in the Departments of Chemistry, Physics, Statistics, Engineering, Biological Sciences and the Medical School. Building on this philosophy, we have responded to the fourth Science and Innovation Call by proposing lectureships in three new interdisciplinary research areas (Chemometrics and Experimental Design, Chemical and Structural Characterisation of Materials, and Mass Spectrometry) that will be combined with diverse research in Analytical Science at Warwick to found a new Centre for Analytical Science, expected to boost the profile of Analytical Science in the UK and world-wide. Recognising the fact that scientific progress crucially depends on communication and collaboration between different disciplines and sectors, a central aim of the Centre will be to bring together people from academia and industry with the objective of providing a platform for identification, definition, and implementation of new Analytical Science research goals including the development of new instrumentation, and new methods for data acquisition and statistical inference. The process of innovation requires a dialogue between academia and the private sector. As stated in the Lambert report, the best forms of knowledge transfer involve human interaction . Therefore, the Centre will have an academic/industrial Advisory Board, and will develop, through its new Analytical Forum, a visitor and outreach programme, not only to enable the exchange of ideas, knowledge, and technology between developers and users of analytical tools in public and private sectors, but also to foster new collaborations.Applicants of the very highest quality will be attracted by offering excellent research facilities supported by PhD students and post-doctoral researchers in a well resourced multinational, multidisciplinary environment. The Centre will develop training programmes in Analytical Science, statistics and transferable skills. The integration of research and education in the Centre will offer a comprehensive approach to Analytical Science, helping to provide the UK with the skills base essential to remain internationally competitive.Warwick will nurture the new Centre by guaranteeing long-term support for the area, and by investing heavily in state-of-the-art equipment, purpose-built accommodation and infrastructure. There will be development of modules for CPD, PG and UG training which will help sustainability.
Publications
Li H
(2012)
Protein flexibility is key to cisplatin crosslinking in calmodulin.
in Protein science : a publication of the Protein Society
Lin TY
(2012)
A low noise single-transistor transimpedance preamplifier for Fourier-transform mass spectrometry using a T feedback network.
in The Review of scientific instruments
Pandey P
(2012)
Resolving the Nanoscale Morphology and Crystallographic Structure of Molecular Thin Films: F 16 CuPc on Graphene Oxide
in Chemistry of Materials
Wilson N
(2013)
Weak mismatch epitaxy and structural Feedback in graphene growth on copper foil
in Nano Research
Lopez-Clavijo A
(2013)
Tandem mass spectrometry for the study of glyoxal-derived advanced glycation end-products (AGEs) in peptides
in Rapid Communications in Mass Spectrometry
Qi Y
(2013)
Absorption-mode Fourier transform mass spectrometry: the effects of apodization and phasing on modified protein spectra.
in Journal of the American Society for Mass Spectrometry
Pizarro A
(2013)
Comprehensive Inorganic Chemistry II
Pandey P
(2013)
Pd-doped reduced graphene oxide sensing films for H2 detection
in Sensors and Actuators B: Chemical
Barry NP
(2013)
Exploration of the medical periodic table: towards new targets.
in Chemical communications (Cambridge, England)
Nightingale A
(2013)
Large-scale synthesis of nanocrystals in a multichannel droplet reactor
in Journal of Materials Chemistry A
Qi Y
(2013)
Mapping the protein-binding sites for novel iridium(III) anticancer complexes using electron capture dissociation.
in Rapid communications in mass spectrometry : RCM
Kilgour DP
(2013)
Autophaser: an algorithm for automated generation of absorption mode spectra for FT-ICR MS.
in Analytical chemistry
Dyson M
(2013)
A new approach to high resolution, high contrast electron microscopy of macromolecular block copolymer assemblies
in Soft Matter
Marsden A
(2013)
Is graphene on copper doped?
in physica status solidi (RRL) - Rapid Research Letters
Wei J
(2013)
Structural characterization of chlorophyll-a by high resolution tandem mass spectrometry.
in Journal of the American Society for Mass Spectrometry
Wei J
(2014)
D-a-tocopheryl polyethylene glycol 1000 succinate: a view from FTICR MS and tandem MS.
in Analytical chemistry
Li H
(2014)
Mass spectrometric strategies to improve the identification of Pt(II)-modification sites on peptides and proteins.
in Journal of the American Society for Mass Spectrometry
Carter R
(2014)
Band gap expansion, shear inversion phase change behaviour and low-voltage induced crystal oscillation in low-dimensional tin selenide crystals.
in Dalton transactions (Cambridge, England : 2003)
Sun L
(2014)
Structural reorganization of cylindrical nanoparticles triggered by polylactide stereocomplexation.
in Nature communications
Lopez-Clavijo AF
(2014)
Study of an unusual advanced glycation end-product (AGE) derived from glyoxal using mass spectrometry.
in Journal of the American Society for Mass Spectrometry
Barry NP
(2014)
Precious metal carborane polymer nanoparticles: characterisation of micellar formulations and anticancer activity.
in Faraday discussions
Mukherjee A
(2014)
Human Serum Transferrin Fibrils: Nanomineralisation in Bacteria and Destruction of Red Blood Cells
in ChemBioChem
Barry N
(2014)
100 years of metal coordination chemistry: from Alfred Werner to anticancer metallodrugs
in Pure and Applied Chemistry
Barry NP
(2014)
Fabrication of crystals from single metal atoms.
in Nature communications