MRC Centre for Global Infectious Disease Analysis

Lead Research Organisation: Imperial College London
Department Name: School of Public Health

Abstract

The continuing threat from new infectious diseases has been highlighted in recent years by the emergence of MERS-coronavirus in the Middle East, Ebola in West Africa and Zika in Latin America. Preparing for and responding to such threats is a priority for public health agencies and governments worldwide. Equally importantly, as scientific research delivers new approaches to controlling existing infectious diseases such as malaria, HIV, tuberculosis and polio, there is a need to determine what interventions are likely to work best to limit the disease and illness caused by a specific disease in a particular setting.

In this context, computer modelling of the spread of diseases in populations coupled with scientifically rigorous data analysis have proven themselves as powerful tools for giving insight into how diseases spread and what can be done to limit that control that spread. The Centre for Global Infectious Disease Analysis undertakes research on these scientific methods and applies them to disease threats of concern.

A key feature of the Centre is the close links it has made with with public health agencies - such as the Public Health England, the Centers for Disease Control and Prevention in the US (CDC), and the World Health Organization (WHO) - organisations which have to formulate and implement strategies to control infectious diseases.

Senior scientists in the Centre are world-leaders in infectious disease modelling and analysis. They have broad experience in responding to real epidemics, and undertaking epidemiological research on endemic diseases (such as malaria, HIV, tuberculosis and polio). Their work directly influences disease control policy through the many interactions the Centre has with public health organisations and governments.

Funding provided by MRC and Imperial College has allowed dedicated investment into the development of close collaborative partnerships with PHE, CDC and WHO and governments and research centres in many low and middle income countries (LMICs). We also work closely with other important organisations who work on improving health in LMICs (notably the Bill and Melinda Gates Foundation, The Global Fund and Gavi). With each, our collaborative research has both scientific interest to Centre researchers and contributes to the evidence base for public health decisions. Centre funding supports a core technical capacity available to all projects and pays for dedicated liaison staff who facilitate and enhance our partnerships with major global health organisations and LMICs.

MRC funding has also facilitated a greater focus on collaboration, training and career development within the Centre - training the next generation of quantitative infectious disease epidemiologists. We are also involved in increasing knowledge of advanced modelling methods in public health institutions and the wider infectious disease research community, and so have run a large number of introductory short-courses and workshops (in 13 countries in the last 5 years)

This applied activity depends on more fundamental research undertaken in the Centre on the transmission dynamics of different diseases, how diseases evolve genetically over time, and on analysing new approaches to control or treat diseases. This research is interdisciplinary, with Centre researchers working with leading clinical and experimental scientists around the world.

Continued Centre funding will allow existing partnerships to be sustained and enhanced, and new collaborations with researchers and health agencies in LMICs to be developed. By supporting PhD training and postdoctoral career development, it will also continue to expand the UK skill base in mathematical modelling and advanced analysis applied to health problems. Last, continued MRC support will pump-prime new priority research areas, including work on improving the development of new vaccines and on tackling the global challenge posed by antimicrobial resistance.

Technical Summary

The continued threat posed by emerging infectious diseases has been highlighted in recent years by the emergence of MERS-coronavirus in the Middle East, Ebola in West Africa and Zika in Latin America. Preparedness therefore remains a policy priority for public health agencies and governments worldwide. In addition, as new vaccines, drugs and other interventions are developed for endemic diseases such as malaria, HIV and TB, there is a need to extrapolate from clinical trial results to determine which combination of interventions gives the optimal (or most cost-effective) control strategy for a specific disease in a particular setting.

In this context, modern epidemiological modelling and analysis methods have proven themselves increasingly powerful tools for giving insight into the patterns of emergence of novel outbreaks, the transmission dynamics of endemic diseases and the options available for the control of both. The Centre for Global Infectious Disease Analysis is a world leader in research in this area, and in translating our research into improved public-health decision-making. Since it was founded, MRC funding has supported this translation by facilitating the forging of close partnerships with all major global health organisations (e.g. WHO, PHE, CDC, BMGF, The Global Fund, Gavi) and research centres and public health agencies in many low and middle income countries (LMICs).

Continued funding for the Centre will allow existing partnerships to be sustained and enhanced, and new collaborations with researchers and health agencies in LMICs to be developed. By supporting PhD training and postdoctoral career development, it will also continue to expand the UK skill base in mathematical modelling and advanced analysis applied to health problems. Last, continued MRC support will pump-prime new priority research areas, including work on improving the development of new vaccines and on tackling the global challenge posed by antimicrobial resistance.

Planned Impact

A primary aim of the MRC Centre for Global Infectious Disease Analysis is to have societal as well as academic impact - both in the UK and across the world. Our goal is to improve public and global health decision making in relation to infectious disease control through the use of advanced statistical and mathematical modelling methods, whether in emergencies like the West African Ebola epidemic in 2014, or in improving control of major infectious disease killers like HIV, malaria and Tuberculosis. We believe the only effective way of delivering on this goal is to form long-term collaborative partnerships with the leading public and global health organisations world-wide, providing analytical support and capacity building for those partners.

Since the Centre was founded in 2008, we have worked on dozens of policy-relevant problems with decision-makers around the world. We provided real-time support to the World Health Organization (WHO), the governments of the UK, and many other international partners during the 2001 H1N1 influenza pandemic, in relation to continued outbreaks of MERS coronavirus in the Middle East, during the 2014-15 West African Ebola epidemic, and, most recently, during the Latin American Zika epidemic. In addition, we have worked closely with WHO and the major international organisations (e.g. The Global Fund, Gavi and the Bill and Melinda Gates Foundation [BMGF]) that fund infectious disease control efforts in low income countries on HIV, malaria, tuberculosis, polio, influenza and a wide range of other diseases. Our relationship with BMGF is of particular strategic importance - it is both the largest funder of Centre research, but more importantly is a key stakeholder in global health decision-making.

These interactions, and our consequent impact on policy, is facilitated by staff dedicated to acting as liaisons between the scientists working in the Centre and the staff of the global and public health agencies we work with. Indeed, in times of crisis, we embed our staff in some of those key organisations. Recently, one of our researchers joined a WHO field mission to the Democratic Republic of Congo to help that country respond to an outbreak of Ebola.

In addition to formal research outputs, often the most important value we give to these organisations is advice provided from a dynamical modelling perspective. This analytical advisory role is multifaceted: from improving situational awareness in crises, advising on likely impact of interventions for endemic diseases, undertaking rapid analyses of priority questions, and advising on improving surveillance and data capture systems.

Capacity building within our partners is another priority, through informal skills transfer and formal training. The former occurs as a natural result of the degree of interaction, and for the latter we run short-courses, both in the Centre and at our partners' sites. Increasingly, we have also been undertaking capacity-building in low and middle income countries [LMIC], either by running disease-specific workshops with local ministries of health, or by training able local scientists. This activity will be further emphasised in the future.

In addition to impact on public health, we have also been increasing our collaborations with the pharmaceutical industry, most notably with vaccine manufacturers. In the last 5 years we have worked closely with GSK and Sanofi Pasteur, helping to characterise the effectiveness of their malaria and dengue vaccines, respectively. Our work involved analysing the data those companies collected on their products during clinical trials and advising them, WHO and regulatory agencies on how their vaccines might best be used. We also work with a wide range of public-private product development partnerships developing new vaccines, drugs and vector control measures.

Attached letters of support from UK DoH, GoS, PHE, US CDC, WHO and BMGF highlight the public health impact of the Centre.

Organisations

Publications

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Baggaley RF (2018) Does per-act HIV-1 transmission risk through anal sex vary by gender? An updated systematic review and meta-analysis. in American journal of reproductive immunology (New York, N.Y. : 1989)

 
Description Advise to Chinese government to set up national procurement
Geographic Reach Asia 
Policy Influence Type Participation in a advisory committee
Impact Centralized national procurement process for pharmaceuticals was established in China based on this advise, launched in 2018.
 
Description Advisory Board of Parasites & Vectors
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Shaping up the scope of the journal; engagement with contributors; advising the Editor-in-Chief
 
Guideline Title 2018 BASHH UK national guideline for the management of infection with Mycoplasma genitalium
Description British Association for Sexual Health and HIV guidelines on public health management of Mycoplasma genitalium and antimicrobial resistance
Geographic Reach National 
Policy Influence Type Citation in clinical guidelines
URL https://www.bashh.org/news/news/bashh-launches-new-nice-accredited-guidelines-to-help-prevent-mycopl...
 
Description Co-wrote a WHO protocol for assessing non-inferiority of bednets and indoor residual sprays
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact We have devised a protocol to enable novel vector control products that are part of an existing intervention class to be recommended by the WHO (and therefore purchased by the Global Fund) without the need to go through expensive randomised control trials.
 
Description Collaboration with WHO Global Malaria Programme
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact This publication was cited in new policy guidance for the use of current rapid diagnostic tests for malaria, including guidance on when to switch test type if resistance mutations are present.
URL https://www.who.int/malaria/mpac/en/
 
Description Commonwealth Heads of Government Malaria Committment
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
URL https://www.malariasummit.com/
 
Description Comparison of different brands of bed nets
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Determine methods to ensure that bed nets procured by governments and charitable organisations are of an efficient standard
 
Description Continue to have an impact on global polio policy. This is on-going
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Guidance on vaccine choice during polio erradication endgame
 
Description Contribution to Kenya's National Strategic Plan for TB control
Geographic Reach National 
Policy Influence Type Citation in other policy documents
 
Description Elimination Scenario Planning Exercise with Senegal & The Gambia
Geographic Reach Africa 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
Impact Supported by The Global Fund, in 2016-2017 we undertook three workshops to support malaria country programme planning with The Gambia and Senegal. The last of these, in March 2017, was a joint workshop between the two programmes in which we coordinated discussions surrounding cross-border collaboration between the two countries. Our role in supporting the establishment of this new collaboration was acknowledged at the Malaria Summit held ahead of the Commonwealth Heads of Government meeting by the President of The Gambia (see URL below - we are mentioned in the film). A formal collaboration between the two countries was signed in January 2019.
URL https://www.malariasummit.com/
 
Description GAVI Vaccine Investment Strategy
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact Membership of the GAVI Vaccine Investment Strategy Committee which provided the scientific input for the recommendation of new vaccines to be supported by GAVI in the upcoming replenishment. This has a direct impact on worldwide childhood vaccination strategies.
URL https://www.gavi.org/about/strategy/vaccine-investment-strategy/
 
Description HPCs-UNAIDS
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a national consultation
 
Description HPCs-Zimbabwe
Geographic Reach National 
Policy Influence Type Participation in a national consultation
 
Description Informing strategic priorities for TB elimination in Mumbai, India
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
 
Description Malaria Policy Advisory Committee
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact This committee provides advice directly to the WHO Global Malaria Programme on all topics relevant to malaria control and elimination. WHO guidance has direct impact on the policies adopted by national government, which over the past year has included amendment of treatment protocols, advice on current and new prevention interventions, allocation of global donor funding and certification of malaria elimination.
URL https://www.who.int/malaria/mpac/en/
 
Description Member of Executive Management of Neglected Tropical Disease Modelling Consortium
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
 
Description Membership of regional WHO advisory committee on multi-drug-resistant TB in South East Asian Region
Geographic Reach Asia 
Policy Influence Type Participation in a advisory committee
 
Description Methods development for global HIV estimates and projections
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
Impact We developed new mathematical models used to estimate and project trends in the global HIV epidemic. These models are used by all countries in sub-Saharan Africa and over 150 countries globally to develop official national estimates of their HIV epidemic and plan, budget, and allocate resources to the HIV response. Estimates are reported by UNAIDS as official global HIV estimates and projection, and they form consensus estimates underpinning resource allocation by the US President's Emergency Plan for AIDS Relief (PEPFAR) and the Global Fund to fight HIV, TB, and Malaria.
URL http://aidsinfo.unaids.org
 
Description Pandemic influenza preparedness - advice to government
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
Impact Effective preparedness and response to pandemics, which are the highest category of risk identified on the National Risk Register of Civil Emergencies. This is an ongoing activity, supported by multiple relevant grants spanning different time-periods.
 
Description Presentation and participation in WHO Technical Consultation in Research priorities for the use of more highly sensitive diagnostics during pregnancy
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
URL https://www.who.int/malaria/mpac/mpac-april2018-hi-sensitive-tests-session5.pdf?ua=1
 
Description Publication of work about Evidence Synthesis for Policy
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
URL https://royalsociety.org/topics-policy/projects/evidence-synthesis/
 
Description Published estimates of Impact of President's Malaria Initiative used in 12th annual report to congress
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact Our estimates, published in PLoS Medicine, of the impact of the PMI since it's conception were used by PMI in it's report to congress. This report is used to advocate for resources for malaria prevention across 19 focus countries, amid a time when the US' contribution to foreign aid was being questioned.
URL https://www.pmi.gov/docs/default-source/default-document-library/pmi-reports/2018-pmi-twelfth-annual...
 
Description RDTs-WHO
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a national consultation
Impact Evidence generated on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment contributed to a decision in Zimbabwe (and possibly elsewhere) to adopt a World Health Organisation recommendation to implement repeat HIV testing prior to initiating people onto antiretroviral treatment. This change in policy will reduce the numbers of HIV-negative people put on potentially life-long treatment, will reduce the occurrence of unnecessary side effects, and will reduce unnecessary expenditure.
 
Description Support MSF surveillance of malaria policy
Geographic Reach Multiple continents/international 
Policy Influence Type Participation in a advisory committee
Impact Provided evidence to allow MSF to monitor malaria severity using antinatal clinic data
URL http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114784
 
Description Support the development of guidelines for malaria surveillance in near-elimination settings. We have outlined a set of questions that should be asked to estimate whether an identified case of malaria was acquired locally or imported from abroad. These include statements on the time and location of travel, duration of stay and date of arrival of symptoms. Questions trailed in regions of South Africa.
Geographic Reach Africa 
Policy Influence Type Influenced training of practitioners or researchers
 
Description UNAIDS reference group
Geographic Reach Multiple continents/international 
Policy Influence Type Membership of a guideline committee
Impact From 2015 to 2018, I co-chaired the UNAIDS Reference Group on Estimates, Modelling and Projections. This group advises UNAIDS and WHO on the methods used to generate international estimates of HIV infection and it's demographic impact. During this period, significant progress was made in improving these estimates - for example, for children infected with HIV, by incorporating age-structure into the models, and in producing local estimates of levels of HIV infection - that can be used to strengthen national HIV control programmes and, thereby, to further reduce levels of new infections and mortality.
URL http://www.epidem.org/
 
Description WHO Flu Burden
Geographic Reach Multiple continents/international 
Policy Influence Type Influenced training of practitioners or researchers
 
Description WHO world malaria report
Geographic Reach Africa 
Policy Influence Type Citation in other policy documents
Impact Tracking of ITN numbers and use
 
Description A genealogical approach to tracking bacterial transmission
Amount £403,170 (GBP)
Funding ID MR/N010760/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 05/2016 
End 05/2019
 
Description APW WHO Global Malaria Programme
Amount £17,932 (GBP)
Funding ID 202011200 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 06/2018 
End 03/2019
 
Description Analysis of ALPHA Network
Amount £37,490 (GBP)
Funding ID PR2017/724002 EPPHZL91/IMPERIAL 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS) 
Sector Public
Country Global
Start 12/2017 
End 11/2018
 
Description Analytic and sequencing tools for poliovirus environmental surveillance
Amount £876,522 (GBP)
Funding ID OPP1171890 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 05/2017 
End 11/2020
 
Description Antibiotic Resistance: Mathematical modelling simulating the evolutionary response of genococcus within human populations to gepotidacin use
Amount £151,716 (GBP)
Funding ID 3000862100 
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start 06/2017 
End 06/2019
 
Description Assessing the impact of waning vaccine efficacy on malarial elimination using a population transmission model
Amount £61,597 (GBP)
Funding ID GAT.0888-30-01320457-COL 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2016 
End 11/2018
 
Description Assessing the risk that chytridiomycosis poses to the megadiverse amphibian community of Madagascar
Amount £117,569 (GBP)
Funding ID D16ZO-022 
Organisation Morris Animal Foundation 
Sector Charity/Non Profit
Country United States
Start 09/2016 
End 08/2019
 
Description BMGF Project Grant: Vaccine Modelling Initiative (VMI) 2
Amount £965,440 (GBP)
Funding ID OPP1092240 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 06/2013 
End 06/2019
 
Description Building International Collaborations on the Mathematical Modelling of Emerging Infectious Disease Threats (Neil Ferguson)
Amount £49,657 (GBP)
Funding ID P11329/DF118 
Organisation Imperial College London 
Department Imperial College Trust
Sector Charity/Non Profit
Country United Kingdom
Start 04/2008 
End 12/2020
 
Description Building TRUST
Amount £100,609 (GBP)
Funding ID Sub Award No. 1800014 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 07/2015 
End 06/2019
 
Description Control of TB in India: developing analytical tools
Amount £385,936 (GBP)
Funding ID OPP1095710 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2013 
End 04/2019
 
Description Defining disease importation and target interventions from routine surveillance data
Amount $100,000 (USD)
Funding ID OPP1161898 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2016 
End 04/2018
 
Description Develop a novel, cost-effective, surveillance approach for malaria elimination through existing antenatal care platform
Amount £56,255 (GBP)
Organisation PATH 
Sector Private
Country Global
Start 02/2018 
End 08/2018
 
Description Development and pilot implementation of rapid poliovirus detection and sequencing from stool samples using nanopore technology
Amount £197,654 (GBP)
Funding ID OPP1207299 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2018 
End 09/2019
 
Description Development of Methods to Measure and Interpret HIV Prevention Cascades in Population-Based Surveys
Amount £766,317 (GBP)
Funding ID OPP1161471 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2016 
End 02/2019
 
Description Deworm3 unit for transmission dynamics, trial simulation and data analysis
Amount £1,163,766 (GBP)
Funding ID SON15004 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 04/2016 
End 09/2020
 
Description Dynamic Modelling of HSV-2 and HIV Infections to Estimate the Burden of HSV-associated HIV Infections and the Predicted Impact of HSV Vaccines
Amount £103,754 (GBP)
Funding ID 202002015 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 05/2018 
End 05/2019
 
Description Early antiretroviral therapy and pre-exposure prophylaxis for HIV prevention among emale sex workers in Benin, West Africa
Amount £121,857 (GBP)
Funding ID OPP1098973 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 08/2014 
End 12/2018
 
Description Epidemiological analysis and mathematical modelling of poliovirus elimination and endgame vaccination strategies
Amount £236,130 (GBP)
Funding ID 2017/769688-0 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 11/2017 
End 08/2019
 
Description Evolutionary dynamics underlying pneumococcal genomic diversity.
Amount £708,513 (GBP)
Funding ID 104169/Z/14/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2014 
End 09/2019
 
Description Explore the Pathway of China NICE-like Mechanism by Piloting Three Suggested Projects
Amount £172,623 (GBP)
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 12/2017 
End 05/2019
 
Description Geospatial modelling for malaria risk stratification and intervention targeting
Amount £219,507 (GBP)
Funding ID 1606H5002/JH6 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 09/2016 
End 08/2020
 
Description HC-HIV modeling activity
Amount £156,940 (GBP)
Funding ID 48345 
Organisation United States Agency for International Development 
Sector Public
Country United States
Start 06/2017 
End 08/2018
 
Description HIV Modelling Consortium Renewal
Amount £3,527,347 (GBP)
Funding ID OPP1084364 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 06/2013 
End 01/2019
 
Description Health in a changing climate: the dynamic challenge of snake bite in South Asia
Amount £512,673 (GBP)
Funding ID MR/P024513/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2017 
End 03/2019
 
Description Human Infectious Challenge Vaccine (HIC vac) network
Amount £2,041,189 (GBP)
Funding ID MR/R005982/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 05/2018 
End 04/2019
 
Description Immunological investigation for the implenatation of Live Attenuated Influenza Vaccination
Amount £811,303 (GBP)
Funding ID MR/R021643/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 06/2018 
End 06/2021
 
Description Impact of maternally derived antibodies and microbiota on the immunogenicity of rotavirus vaccines in African, Indian and European infants
Amount £255,266 (GBP)
Funding ID JXR11990 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 07/2015 
End 12/2018
 
Description Improving the efficacy of malaria prevention in an insecticide resistant Africa
Amount £162,798 (GBP)
Funding ID 200222/B/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2016 
End 01/2019
 
Description Integrating Ethics and Equity into Priority Setting for Universal Health Coverage: A Proof-of-Concept Study in South Africa
Amount £128,944 (GBP)
Funding ID 208045/Z/17/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2017 
End 01/2020
 
Description Joint estimation of HIV and adult mortality trends in sub-Saharan Africa
Amount £67,680 (GBP)
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 08/2018 
End 12/2019
 
Description Key populations and HIV epidemics in Sub-Saharan Africa: Developing better epidemiologic tools to inform priorities and programs
Amount £179,258 (GBP)
Funding ID PO: 2003388501 
Organisation FHI 360 
Sector Charity/Non Profit
Country United States
Start 06/2016 
End 03/2019
 
Description Kris Parag: Minimum Models for Optimal Epidemic Monitoring and Control
Amount £288,432 (GBP)
Funding ID MR/S019693/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2018 
End 10/2021
 
Description London Centre for NTD Research
Amount £555,000 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start 06/2015 
End 05/2019
 
Description London Centre for NTD Research (renewal 3)
Amount £785,649 (GBP)
Organisation GlaxoSmithKline (GSK) 
Sector Private
Country Global
Start 06/2018 
End 05/2021
 
Description MIDAS 2: Models for synthesising molecular, clinical and epidemiological data, and translation to public health response (NIH)
Amount £1,208,953 (GBP)
Funding ID 1U01GM110721-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2014 
End 05/2019
 
Description MIDAS: Modeling Epidemic Infectious Diseases Using Sequence Analysis
Amount £184,667 (GBP)
Funding ID 258162IMP 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 01/2016 
End 05/2019
 
Description Manon Ragonnet: Beyond 90-90-90: Phylodynamic analysis to guide HIV surveillance, control & elimination
Amount £293,580 (GBP)
Organisation Imperial College London 
Sector Academic/University
Country United Kingdom
Start 11/2018 
End 11/2021
 
Description Mapping the risk of international infectious disease spread
Amount £111,089 (GBP)
Funding ID AID-OAA-F-16-00115 
Organisation United States Agency for International Development 
Sector Public
Country United States
Start 10/2016 
End 12/2018
 
Description Mathematical Modelling of Microfilaricidal Drugs for River Blindness: from Patients to Populations
Amount £50,870 (GBP)
Organisation Drugs for Neglected Diseases initiative (DNDi) 
Sector Private
Country Switzerland
Start 06/2016 
End 05/2019
 
Description Mathematical modeling in the HPTN Renewal
Amount £622,568 (GBP)
Funding ID 2UMIAI068617 Sub#0000800798 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 01/2014 
End 11/2020
 
Description Mathematical modelling of poliovirus transmission to support the endgame
Amount £487,817 (GBP)
Funding ID OPP1099374 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2013 
End 07/2018
 
Description Model development for the draft WHO global report on insecticide resistance in malaria vectors
Amount £13,901 (GBP)
Funding ID 2018/797131-0 
Organisation World Health Organization (WHO) 
Sector Public
Country Global
Start 03/2018 
End 12/2018
 
Description Model development for the draft WHO global report on insecticide resistance in malaria vectors
Amount £258,706 (GBP)
Organisation IVCC 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2018 
End 02/2020
 
Description Modeling Anorectal HIV Transmission in Women
Amount £288,589 (GBP)
Funding ID 5R01AI057020 Sub#201224310-05 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 11/2014 
End 05/2019
 
Description Modelling antimalarial target product profiles for reducing P. falciparum malaria transmission
Amount £316,782 (GBP)
Funding ID PO14/00561 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 10/2013 
End 02/2019
 
Description Modelling in support of India program , development and use of new tools and programmatic prioritization
Amount £247,862 (GBP)
Funding ID OPP1205227 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2018 
End 10/2020
 
Description Modelling the Elimination of Onchocerciasis in Cameroon (International Exchanges)
Amount £11,999 (GBP)
Funding ID IES/R2/181017 
Organisation The Royal Society 
Sector Academic/University
Country United Kingdom
Start 12/2018 
End 12/2020
 
Description Modelling the potential impact of intermittent preventive treatment of malaria in pregnancy on antimalarial drug resistance
Amount £99,998 (GBP)
Funding ID ch160084 
Organisation Royal Society of Medicine 
Sector Learned Society
Country United Kingdom
Start 12/2016 
End 08/2018
 
Description Multi-Level Behavioral Economics and Community Psychology Approaches to Strengthen HIV Prevention Cascades in Adolescent Girls and Young Women in East Zimbabwe
Amount $715,142 (USD)
Funding ID 1R01MH114562-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2017 
End 07/2021
 
Description Multidisciplinary Studies of HIV/AIDS and Aging (R21)
Amount £205,531 (GBP)
Funding ID 1R21AG053093 - 01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2016 
End 04/2019
 
Description NIHR Senior Investigator Award
Amount £120,000 (GBP)
Funding ID P/O 427921 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2009 
End 04/2021
 
Description NIHR: NIHR HPRU in Modelling Methodology
Amount £4,234,300 (GBP)
Funding ID HPRU-2012-10080 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2014 
End 03/2020
 
Description NTD Consortium Renewal (STH, Schisto, Oncho)
Amount £770,936 (GBP)
Funding ID 1708CR001/VP1 (OPP1184344) 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2017 
End 02/2021
 
Description Near-Infrared Spectroscopy: A One-Stop-Shop for Mosquito Epidemiological Monitoring?
Amount £643,683 (GBP)
Funding ID MR/P01111X/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2017 
End 02/2020
 
Description New Data and Models to Track Progress Towards Reducing New HIV Infections
Amount £861,803 (GBP)
Funding ID OPP1190661 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 05/2018 
End 03/2022
 
Description Newton Fund Researcher Links Grant
Amount £34,450 (GBP)
Funding ID 2016-RLWK7-10289 
Organisation British Council 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2017 
End 01/2018
 
Description Optimal spatial scales for deployment of multiple first line therapies for malaria
Amount £105,750 (GBP)
Funding ID RGF\EA180225 
Organisation Royal Society of Medicine 
Sector Learned Society
Country United Kingdom
Start 12/2017 
End 03/2021
 
Description Phase variable epigenetic regulation in Firmicutes
Amount £298,700 (GBP)
Funding ID RM33G0360 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 01/2016 
End 12/2018
 
Description Population Effects of Antretroviral Therapy to Reduce HIV Transmission (PopART) - Health Economics
Amount £12,000 (GBP)
Organisation UK Department for International Development 
Sector Public
Country United Kingdom
Start 11/2015 
End 03/2018
 
Description Population Effects of Antretroviral Therapy to Reduce HIV Transmission (PopART) - Health Economics
Amount £453,028 (GBP)
Funding ID PO15001410 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 06/2015 
End 11/2018
 
Description Predicting the impact of insecticide resistance and new paradigms of vector control
Amount £161,331 (GBP)
Organisation IVCC 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2015 
End 05/2018
 
Description Predicting the impact of seasonal respiratory infection on temporal dynamics and characteristics of admission rates and time spent in hospital
Amount £115,260 (GBP)
Funding ID RDA02 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 11/2018 
End 10/2020
 
Description Predicting the public health
Amount £190,502 (GBP)
Organisation Malaria GIA Reference Center - PATH MVI 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2018 
End 12/2019
 
Description Progestin-based contraceptive modeling in high DMPA-IM use and high HIV incidence settings
Amount £378,999 (GBP)
Funding ID OPP1194416 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 09/2018 
End 07/2020
 
Description Projections on eliminating NTDs (integrating mapping with modelling)
Amount £73,998 (GBP)
Funding ID OPP1156227 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2016 
End 10/2018
 
Description Projections on eliminating NTDs (integrating mapping with modelling).
Amount £20,392 (GBP)
Funding ID CRR00140 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 11/2017 
End 01/2019
 
Description Providing academic leadership through a Secretariat for the UNAIDS reference group on estimates modelling & projections (2018-2019)
Amount £480,563 (GBP)
Funding ID 2017/778519 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS) 
Sector Public
Country Global
Start 01/2018 
End 12/2019
 
Description Providing academic leadership through a Secretariat for the UNAIDS reference group on estimates modelling & projections (2018-2019)
Amount £480,563 (GBP)
Funding ID 2017/778519 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS) 
Sector Public
Country Global
Start 01/2018 
End 12/2019
 
Description Quantifying Spatial Representativeness and Uncertainty in Antenatal Care Sentinel Surveillance for HIV in Sub-Saharan Africa.
Amount $53,375 (USD)
Funding ID 1R03AI125001-01A1 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 12/2016 
End 11/2018
 
Description Quantifying and preparing for the non-communicable disease burden in the ageing HIV-positive population in Kenya
Amount £134,891 (GBP)
Funding ID OISE-17-62962-1 
Organisation United States President's Emergency Plan for AIDS Relief 
Sector Public
Country United States
Start 08/2017 
End 09/2019
 
Description R01 Statistical Models for Estimating and Projecting HIV/AIDS Epidemics
Amount £11,080 (GBP)
Funding ID 5776-ICS-DHHS-6664 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2017 
End 08/2018
 
Description Research and Development of Reconstructing HIV Epidemics from HIV Phylogenetics
Amount £72,683 (GBP)
Funding ID Ref: 340798 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 06/2018 
End 06/2021
 
Description Research for Health in Conflict (R4HC): multi-sectorial capacity strengthening, partnership building and research across the MENA region
Amount £605,208 (GBP)
Funding ID MOTEAAR 
Organisation Kings BRC 
Sector Academic/University
Country United Kingdom
Start 10/2017 
End 12/2021
 
Description Respiratory Infection Health Protection Research Unit
Amount £88,377 (GBP)
Funding ID IS-HPU-1112-10064 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2014 
End 03/2020
 
Description RooPfs (Can improved housing provide additional protection against clinical malaria over current best practice? A household-randomised controlled trial)
Amount £179,101 (GBP)
Funding ID RF020305 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 11/2014 
End 10/2019
 
Description Schisto Vaccine project extn via NTD Modelling Consortium, Warwick
Amount £121,248 (GBP)
Funding ID OPP1176780 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 09/2017 
End 03/2019
 
Description Sources and Impact of Misclassification Errors in HIV Rapid Testing Algorithms in a Hyper-Endemic HIV Setting in sub-Saharan Africa
Amount £886,781 (GBP)
Funding ID OPP1131208 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 07/2015 
End 03/2019
 
Description TB Modelling and Analysis Consortium
Amount £37,133 (GBP)
Funding ID EPIDZJ6210/Imperial 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 01/2018 
End 12/2018
 
Description Thanzi La Onse -Frameworks and analysis to ensure value-for-money health care: developing theory, changing practices in low- and middle-income settings.
Amount £687,266 (GBP)
Funding ID R18664 
Organisation Research Councils UK (RCUK) 
Sector Public
Country United Kingdom
Start 10/2017 
End 12/2021
 
Description The evolution of influenza virus; Studies of within host and between host evolution to improve pandemic risk assessment and vaccine updates
Amount £1,269,464 (GBP)
Funding ID 200187/Z/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2016 
End 03/2020
 
Description The evolutionary dynamics of multiazole resistance in pathogenic Aspergillus fungi
Amount £427,007 (GBP)
Funding ID NE/P001165/1 
Organisation Natural Environment Research Council 
Sector Public
Country United Kingdom
Start 11/2016 
End 11/2019
 
Description The farm environment: an overlooked reservoir of Mycobacterium bovis?
Amount £21,364 (GBP)
Funding ID RLFEW3022 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 04/2016 
End 05/2019
 
Description The life course of human immune responses to influenza infection and vaccination
Amount £1,882,747 (GBP)
Funding ID 200861/Z/16/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2016 
End 01/2021
 
Description Understanding links between microbial communities and emerging fungal pathogens in complex ecosystems
Amount £492,863 (GBP)
Funding ID NE/S000844/1 
Organisation Natural Environment Research Council 
Sector Public
Country United Kingdom
Start 11/2018 
End 10/2021
 
Description Validation of New Technologies for Diagnostic Evaluation of Tuberculosis (VANTDET)
Amount £1,212,037 (GBP)
Funding ID 12/65/27 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 03/2014 
End 12/2017
 
Description Zika: A fast new intervention and an innovative method of evaluation
Amount £34,518 (GBP)
Funding ID AID-OAA-F-16-00094 
Organisation United States Agency for International Development 
Sector Public
Country United States
Start 10/2016 
End 09/2019
 
Description iDSI 2 (DFID Supplement)
Amount £1,487,180 (GBP)
Funding ID OPP1134345 
Organisation Bill and Melinda Gates Foundation 
Sector Charity/Non Profit
Country United States
Start 04/2017 
End 03/2020
 
Title HPCs-integrated formulations 
Description Generic core and expanded formulations of HIV prevention cascades for use in tracking progress with implementation of efficacious methods of HIV prevention including combination HIV prevention. The core cascade is applied to a population at a given risk of HIV infection and comprises three steps - motivation to use the method(s), accessibility of the method(s), and effective use of the method(s). The core cascade can be used for high-level monitoring and advocacy. The expanded formulation adds factors that can contribute to drop-offs between the main steps in the core cascade which can aid identification of time- and place-specifically appropriate interventions to increase the level of effective use. These cascades can be used in mathematical models to measure the impact of current levels of use of HIV prevention methods on on HIV incidence and evaluate the potential impact of alternative interventions targeted at the different steps in the cascade (i.e. to improve motivation, accessibility and/or effective use). 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2019 
Provided To Others? Yes  
Impact This work contributed to a decision by UNAIDS to adopt HIV prevention cascades as an international framework for tracking progress with implementing primary methods of HIV prevention and to produce international guidelines for countries on formulations to use and methods of measurement. 
 
Title HPCs-questionnaire 
Description Questionnaire comprising questions to measure and interpret HIV prevention cascades for male and female condoms, pre-exposure prophylaxis, voluntary medical male circumcision, sexual partner reduction and combination HIV prevention in general population surveys. 
Type Of Material Model of mechanisms or symptoms - human 
Year Produced 2018 
Provided To Others? No  
Impact None as yet - the tool is currently being piloted in a large population survey in east Zimbabwe 
 
Title RDTs-smartphone camera app 
Description Smartphone camera application developed by our collaborators on the study on HIV misclassification errors (Global Solutions for Infectious Diseases) to collect and transmit images of the outputs from HIV rapid tests used in routine health services - thereby enabling evaluation by external experts of the quality of outputs from these tests and the accuracy of interpretation of these outputs by local clinic staff. 
Type Of Material Physiological assessment or outcome measure 
Year Produced 2016 
Provided To Others? No  
Impact The tool has enabled us to establish that approximately 50% of false-negative HIV test results occurring in routine health services in Zimbabwe could be due to errors by local clinic staff in reading or recording the outputs from HIV rapid tests. 
 
Title All-India TB Model 
Description Model developed in collaboration with India National TB Programme, combining the best available epidemiological and surveillance data to capture India's TB epidemic on a national level. The model now forms the basis for different modelling analyses, conducted by the group, relating to TB in India. 
Type Of Material Computer model/algorithm 
Year Produced 2018 
Provided To Others? Yes  
Impact Model is currently being used to help inform India Government on strategic priorities for TB control in the country 
 
Title Develop statistical methods for determining whether a cases of malaria was acquired in the country of detection or imported from abroad. 
Description Develop a Bayesian method of taking a persons travel history, details of malaria endemicity and seasonality of transmission and determining the percentage likelihood that the case of malaria was: (1) acquired at home, (2) imported from abroad, (3) imported from another region of the country (4) was of unknown origin. 
Type Of Material Data analysis technique 
Year Produced 2018 
Provided To Others? No  
Impact None as yet 
 
Title EPP-ASM model for estimation HIV epidemic trends 
Description The EPP-ASM model is a new demographic-structured model for estimating HIV epidemic trends in sub-Saharan Africa. Compared to previously existing tools, the new model better captures the demographic impacts of the HIV epidemic and improves estimates of recent HIV incidence trends in generalised epidemic settings. 
Type Of Material Computer model/algorithm 
Year Produced 2019 
Provided To Others? Yes  
Impact - Model implemented in 2019 version of Spectrum software (v5.73) supported by UNAIDS for global HIV estimates and projections in developed in 2019 (to be published June 2019). - Model and software code utilised for HIV estimation by the Global Burden of Disease study by the Institute for Health Metrics and Evaluation 
URL https://github.com/mrc-ide/eppasm
 
Title Experiments for detection of Plasmodium berghei infected Anopheles stephensi mosquitoes using near-infrared spectroscopy 
Description Spectra from uninfected, indected and infectious mosquitoes 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact None currently 
URL https://doi.org/10.5281/zenodo.1001720
 
Title Fluscape project dataset 
Description Serological data from a study in China 
Type Of Material Database/Collection of data 
Year Produced 2015 
Provided To Others? Yes  
Impact None yet 
URL http://www.fluscape.org
 
Title Household survey in Eastern Zimbawe 
Description Conducting a household survey in Eastern Zimbawe to determine HIV risks as part of a 20 year old study. See Manicaland HIV project (.org) 
Type Of Material Database/Collection of data 
Year Produced 2007 
Provided To Others? No  
Impact This has been going on since 2007 and it is on-going 
 
Title Malaria socio-economic data 
Description qualitative and quantitative data from several West African countries on perceptions of quality, risk, costs and cost effectiveness 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact Too early to identify impacts 
 
Title Manicaland - HPCs 
Description SQL database comprising data from the baseline general population survey for a study to measure and interpret HIV prevention cascades and to evaluate the impact of novel behavioural economics and community psychology interventions to strengthen these cascades in adolescent girls and young women and their male partners. The database includes HIV infection data obtained from provider-initiated HIV testing and counselling (PITC) and, for those who decline PITC, from laboratory tests conducted using dried blood spots collected in the survey. 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact None as yet - data collection still in progress 
 
Title Manicaland - cohort 
Description SQL database comprising data from 6 rounds of a general population cohort survey in Manicaland, east Zimbabwe, with linked HIV test results 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact Data describing and interpreting declines in HIV prevalence, HIV incidence and AIDS mortality within the general population over the period 1998 to 2013. Results have been published in more than 200 scientific papers including Science and The Lancet. The findings from the study led to our being requested by UNAIDS to conduct in-depth investigations into the existence and causes of national HIV decline in Zimbabwe. 
 
Title Manicaland - test & treat 
Description Database containing data extracted from routine programme records at health centres in three districts of Manicaland province for the periods 6 months prior to and 6 months following the introduction of the 'treat all' policy for people living with HIV infection. 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? No  
Impact None as yet. This database was compiled by a PhD student. Papers are currently being drafted for publication. 
 
Title Methodology for spatial mapping 
Description Developed two new statistical approaches. One now underpins the local burden of disease project at IHME 
Type Of Material Computer model/algorithm 
Year Produced 2017 
Provided To Others? Yes  
Impact Model results used widely for policy. 
 
Title Molecular Markers of Anti-malaria Partner Drug Resistence 
Description Systematic review of mutations in Pfmdr1 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact None yet 
URL https://gh.bmj.com/content/3/5/e000999
 
Title Review of the effectiveness of indoor spraying of insecticide for control of malaria 
Description Systematic review of experimental hut trial data 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact Not known yet 
 
Description ALPHA Network 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of data from Manicaland, Zimbabwe for use in pooled and comparative analyses of trends and determinants of HIV incidence in sub-Saharan African countries with generalised epidemics in the post-antiretroviral treatment era. Contributions to analyses of the pooled and site-specific data.
Collaborator Contribution The ALPHA Network coordinated by researchers at the LSHTM sourced funding from BMGF for the project, are designing the data analyses to be conducted in the project, and will be organising data analysis workshops and results dissemination activities for the project.
Impact No outputs as yet
Start Year 2019
 
Description Alzheimers Disease Epidemiology Research Group (ADERG) 
Organisation Erasmus University Rotterdam
Country Netherlands 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data, equipment and facilities.
Impact Scientific publucations
Start Year 2017
 
Description Alzheimers Disease Epidemiology Research Group (ADERG) 
Organisation University of Gothenburg
Country Sweden 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data, equipment and facilities.
Impact Scientific publucations
Start Year 2017
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation Africa Health Research Institute
Country South Africa 
Sector Charity/Non Profit 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation Biomedical Research and Training Institute (BRTI)
Country Zimbabwe 
Sector Charity/Non Profit 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation Kenyan Institute for Medical Research (KEMRI)
Country Kenya 
Sector Public 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Department Alpha Network
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Department Department of Population Health
Country United Kingdom 
Sector Academic/University 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation MRC/UVRI Uganda Research Unit on AIDS
Country Uganda 
Sector Public 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation Rakai Health Sciences Program
Country Uganda 
Sector Public 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Analysing Longitudinal Population cohort data on HIV/AIDS in Africa (ALPHA) Network 
Organisation University of the Witwatersrand
Country South Africa 
Sector Academic/University 
PI Contribution - Mathematical modelling, demographic analysis, and epidemiological analysis of general population HIV cohort studies in southern and eastern Africa.
Collaborator Contribution - Collection, curation, and analysis of general population HIV cohort studies in southern and eastern Africa - Organization of workshops and support for research dissemination from population cohort study research partners - Methodological training and skills development for scientists based at partner research sites
Impact - Multiple publications in peer reviewed journals: http://alpha.lshtm.ac.uk/publications/ - Inputs to global HIV epidemic estimates and HIV policy at UNAIDS and WHO
Start Year 2013
 
Description Baylor School of Medicine (Sasirekha Ramani) 
Organisation Baylor School
PI Contribution Lead coordinator on a study and design of clinical study design
Collaborator Contribution Rotavirus virology
Impact Not yet
Start Year 2016
 
Description Bristol University 
Organisation University of Bristol
Department Proteomics Facility
Country United Kingdom 
Sector Academic/University 
PI Contribution Modelling, data analysis
Collaborator Contribution Economic analysis and modelling. Supervision of researchers.
Impact Publications on the impact of the Avahan intervention in India. On-going HIV projects funded by linkages. A collaboration HSV 2 vaccination.
 
Description CDC Outbreak 
Organisation Centers for Disease Control and Prevention (CDC)
Country United States 
Sector Public 
PI Contribution Developing rapid methodologies for analysis of fungal disease outbreaks
Collaborator Contribution Methodological and technological advances
Impact Ongoing manuscript preparation
Start Year 2014
 
Description Capacity building for research in conflict 
Organisation King's College London
Department Fondation Peters, King's College London
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Co-Principle Investigators on the project on capacity building for research in conflict.
Collaborator Contribution Co-Principle Investigators on the project on capacity building for research in conflict.
Impact Papers currently in draft.
Start Year 2018
 
Description Capacity building for research in conflict 
Organisation University of Cambridge
Department Cambridge Neuroscience
Country United Kingdom 
Sector Academic/University 
PI Contribution Co-Principle Investigators on the project on capacity building for research in conflict.
Collaborator Contribution Co-Principle Investigators on the project on capacity building for research in conflict.
Impact Papers currently in draft.
Start Year 2018
 
Description Central TB Division, Ministry of Health, Government of India 
Organisation Indian Ministry of Health
Country India 
Sector Public 
PI Contribution Ongoing work with Central TB Division to develop a modelling framework that can help them prioritise their TB control efforts across the country
Collaborator Contribution Developing the analytical framework in collaboration with national TB programme; coordinating with the programme to ensure that the model is maximally applicable; subcontracting additional analytical support from relevant experts in India
Impact Work ongoing
Start Year 2018
 
Description Collaboration with Natashia Morris, Health GIS Centre, MRC South Africa 
Organisation Medical Research Council of South Africa (MRC)
Country South Africa 
Sector Public 
PI Contribution We have been in discussions with Dr Natashia Morris the Manager Health GIS Centre about how to determine whether a case of malaria identified by routine surveillance was contracted in country or imported from abroad. We have presented our methods and Dr Morris is looking to put into place systems which would allow the probability that a case of malaria was imported to be calculated instead of dichotomous decisions based on personal opinion.
Collaborator Contribution Provided information on data collected by the South African national malaria control programme and other countries in the E8 Partnership.
Impact None as yet.
Start Year 2018
 
Description Consultancy to develop guidelines for National Malaria Programmes for stratification, prioritisation and optimised resource allocation within strategic planning 
Organisation World Health Organization (WHO)
Department Global Malaria Programme
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution I am developing a document for National Malaria Programmes for stratification, prioritisation and optimised resource allocation within strategic planning as part of a wider drive to use routine malaria surveillance data for operational action.
Collaborator Contribution WHO is providing consultancy pay as well as general guidance and feedback
Impact No outputs to date.
Start Year 2019
 
Description DFID Ebola Situational Reports 
Organisation Government of the UK
Department Department for International Development (DfID)
Country United Kingdom 
Sector Public 
PI Contribution We have continued to share reports of the analysis of the ongoing Ebola outbreak in the Democratic Republic of the Congo. This has included projections of future incidence, bed demand, and vaccine demand estimates.
Collaborator Contribution Context for analysis needs e.g. requirements for vaccine demand.
Impact Reports for internal use at DFID and White Hall.
Start Year 2018
 
Description DeWorm3 
Organisation Natural History Museum
Country United Kingdom 
Sector Public 
PI Contribution Intellectual input, expertise and the training of staff.
Collaborator Contribution Intellectual input, expertise and the training of staff.
Impact Scientific journal publications
Start Year 2016
 
Description DeWorm3 
Organisation University of Washington
Country United States 
Sector Academic/University 
PI Contribution Intellectual input, expertise and the training of staff.
Collaborator Contribution Intellectual input, expertise and the training of staff.
Impact Scientific journal publications
Start Year 2016
 
Description Detection and Management of Ivermectin Resistance 
Organisation McGill University
Department Institute of Parasitology
Country Canada 
Sector Academic/University 
PI Contribution Mahematical modelling; preparation of papers; successful preparation of grant proposals
Collaborator Contribution Data on genetic analysis of filarial parasites (lymphatic filariasis, onchocerciasis) for mathematical modelling of the evolution and spread of anthelmintic resistance
Impact Outputs in the form of publications: PubMed ID numbers: 19805362; 19154624; 18382607; 17320006; 16834821. Outcomes in the form of invitations to speak at scientific meetings (Am Soc Trop Med Hyg, December 2008; Royal Society UK-Ghana collaboration, April 2008), and Expert Groups (WHO/World Bank, January 2008). Impacts in the form of invitation to belong to the Disease Reference Group on Helminths, World Health Organization.
 
Description Development of Clinical Trial Simulators for Macrofilaricidal Drugs for the Control of Filariases 
Organisation Drugs for Neglected Diseases initiative (DNDi)
Country Switzerland 
Sector Private 
PI Contribution Development of clinical trial modelling simulators (paper in preparation)
Collaborator Contribution Meetings to discuss coordination of project
Impact Presentations to the Bill & Melinda Gates Foundation, American Society of Tropical Medicine and Hygiene, paper in preparation
Start Year 2016
 
Description Development of a viral kinetic model for Dengue infection 
Organisation Johnson & Johnson
Department Janssen Pharmaceuticals
Country United States 
Sector Private 
PI Contribution The aim of the Project is to develop a viral kinetics model for dengue infection in different species that enables evaluating the impact of a prophylactic intervention and/or therapeutic treatment on dengue infection. The goal is to build a viral kinetics model that has the potential to be translatable between species (mice - non-human primates (NHP) - human). The viral kinetics model will be used to gain more insight in the mechanism of action of the direct anti-viral drug candidates and to inform various stages of the drug development process, e.g. in determining different dosing regimens for upcoming studies. The hands-on modeling will be performed by an employee (post-doctoral research fellow) of the UNIVERSITY and a Global Clinical Pharmacology scientist of JANSSEN internally, under the supervision and scientific guidance from the Dengue development team, employees of Quantitative Sciences within JANSSEN, and appropriate representatives of the UNIVERSITY.
Collaborator Contribution The hands-on modeling will be performed by an employee (post-doctoral research fellow) of the UNIVERSITY and a Global Clinical Pharmacology scientist of JANSSEN internally, under the supervision and scientific guidance from the Dengue development team, employees of Quantitative Sciences within JANSSEN, and appropriate representatives of the UNIVERSITY.
Impact N/A at this stage.
Start Year 2019
 
Description Dr. Kounbobr Roch Dabiré of IRSS (Burkina Faso) 
Organisation Research Institute for Health Sciences (IRSS)
Country Burkina Faso 
Sector Public 
PI Contribution We have provided training in the use of spectroscopy and the alalytical methods needed to interpret the results.
Collaborator Contribution Dr Dabiré leads a research team which is extending the methods we have developed to mosquito vectors of malaria in Africa.
Impact Project meeting in London (UK) and Bobo Dioulasso (Burkina Faso).
Start Year 2017
 
Description EIT Cross KIC Education 2018 - Challenge Based Learning 
Organisation University of Grenoble
Country France 
Sector Academic/University 
PI Contribution co-PI
Collaborator Contribution co-PIs
Impact Climate change and Health MOOC: https://www.futurelearn.com/courses/climate-change-public-health
Start Year 2018
 
Description Epidemiology and Control of Cystic Echinococcosis in Peru 
Organisation National University of San Marcos
PI Contribution Participation in and presentations at Newton Fund Workshop in Lima, September 2018
Collaborator Contribution Convening and organisation of Newton Fund Workshop
Impact Multidisciplinary collaboration: epidemiologists, veterinarians, parasitologists, mathematical modellers
Start Year 2018
 
Description Epidemiology and Control of Cystic Echinococcosis in Peru 
Organisation University of Surrey
Country United Kingdom 
Sector Academic/University 
PI Contribution Participation in and presentations at Newton Fund Workshop in Lima, September 2018
Collaborator Contribution Convening and organisation of Newton Fund Workshop
Impact Multidisciplinary collaboration: epidemiologists, veterinarians, parasitologists, mathematical modellers
Start Year 2018
 
Description Epidemiology and Control of Schistosomiasis and Soil-Transmitted Helminthiasis 
Organisation University of Cambridge
Department University of Cambridge, BBSRC IGF Drosophila Genomics Facility
Country United Kingdom 
Sector Academic/University 
PI Contribution Supervision of PhD students, in UK (together with the Schistosomiasis Control Initiative and the Royal Veterinary College) and Australia, for the analysis of data and preparation of joint publications
Collaborator Contribution Sharing of parasitological and epidemiological data pre- and post-implementation of control interventions based on anthelmintic chemotherapy in Africa for joint analysis through shared students
Impact Publications in peer-review journals
 
Description Epidemiology and Control of Schistosomiasis and Soil-Transmitted Helminthiasis 
Organisation University of Queensland
Department University of Queensland Diamantina Institute
Country Australia 
Sector Academic/University 
PI Contribution Supervision of PhD students, in UK (together with the Schistosomiasis Control Initiative and the Royal Veterinary College) and Australia, for the analysis of data and preparation of joint publications
Collaborator Contribution Sharing of parasitological and epidemiological data pre- and post-implementation of control interventions based on anthelmintic chemotherapy in Africa for joint analysis through shared students
Impact Publications in peer-review journals
 
Description Epidemiology and Control of Taeniasis/Cysticercosis 
Organisation Technical University of Munich
Country Germany 
Sector Academic/University 
PI Contribution Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019
Collaborator Contribution Preparation of joint manuscripts
Impact Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation.
Start Year 2017
 
Description Epidemiology and Control of Taeniasis/Cysticercosis 
Organisation University of Ghent
Country Belgium 
Sector Academic/University 
PI Contribution Preparation of joint manuscripts; presentations of talks and posters (e.g. ASTMH); organisation of a workshop on modelling comparison and data needs (EPICYST and CYSTISIM) to take place at Imperial College in March 2019
Collaborator Contribution Preparation of joint manuscripts
Impact Publications under review (e.g. in PLoS Neglected Tropical Diseases) and in preparation.
Start Year 2017
 
Description Epidemiology of Onchocerciasis and Loiasis in Central Africa 
Organisation University of Montpellier
Country France 
Sector Academic/University 
PI Contribution Preparation of joint publications and research proposals that have been successfully funded (e.g. Royal Society)
Collaborator Contribution Sharing of data for joint analysis of parasitological and epidemiological features of infections caused by Onchocerca volvulus and Loa loa
Impact Publications in peer-review journals; reports for World Health Organization (on Alternative Treatment Strategies for onchocerciasis). See also presence in London Centre for Neglected Tropical Disease Research: https://www.londonntd.org/research/projects-search/developing-models-of-loiasis-transmission-to-inform-control-of-the-disease
 
Description Epidemiology of Onchocerciasis and Loiasis in Central Africa 
Organisation University of Yaoundé
Country Cameroon 
Sector Academic/University 
PI Contribution Preparation of joint publications and research proposals that have been successfully funded (e.g. Royal Society)
Collaborator Contribution Sharing of data for joint analysis of parasitological and epidemiological features of infections caused by Onchocerca volvulus and Loa loa
Impact Publications in peer-review journals; reports for World Health Organization (on Alternative Treatment Strategies for onchocerciasis). See also presence in London Centre for Neglected Tropical Disease Research: https://www.londonntd.org/research/projects-search/developing-models-of-loiasis-transmission-to-inform-control-of-the-disease
 
Description Ethics in universal health coverage 
Organisation University of Stellenbosch
Country South Africa 
Sector Academic/University 
PI Contribution Principle investigator for the research project on ethics in universal health coverage.
Collaborator Contribution Co-principle investigator for the research project on ethics in universal health coverage.
Impact Conference presentations, publications in process.
Start Year 2018
 
Description Ethics in universal health coverage 
Organisation University of the Witwatersrand
Department Wits Reproductive Health and HIV Institute
Country South Africa 
Sector Academic/University 
PI Contribution Principle investigator for the research project on ethics in universal health coverage.
Collaborator Contribution Co-principle investigator for the research project on ethics in universal health coverage.
Impact Conference presentations, publications in process.
Start Year 2018
 
Description Floyd Dowell of United States Department of Agriculture 
Organisation U.S. Department of Agriculture USDA
Department Agricultural Research Service
Country United States 
Sector Public 
PI Contribution We have developed new analytical methods to understand how mosquito age, species and infection status (with the malaria parasite) changes the light being measured by a spectrometer
Collaborator Contribution Dr Dowell is a Research Agricultural Engineer who has pioneered work using Near Infrared Spectroscopy to investigate the age of mosquitoes. Dr Dowell provided training and technical advice to scientists from Imperial College London and our partners
Impact Training of UK, Burkinabe and Australian Scientists in the use of spectrometer
Start Year 2017
 
Description FluScape 
Organisation Johns Hopkins University
Department Johns Hopkins Bloomberg School of Public Health
Country United States 
Sector Academic/University 
PI Contribution We run an epidemiological study in Southern China. At imperial we manage the field site and conduct mathematical and statistical analysis.
Collaborator Contribution Johns Hopkins manage the information systems and also conduct mathematical and statistical analysis.
Impact Any paper with Cummings as a co-author.
Start Year 2008
 
Description Foundation for Innovative New Diagnostics 
Organisation Foundation for Innovative New Diagnostics (FIND)
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution Contributing modelling analysis in support of WHO recommendations for new diagnostic tools for tuberculosis
Collaborator Contribution Developing a modelling framework to project the potential impact of new diagnostic tools being supported by FIND, on the TB epidemic in settings such as South Africa. The work will be used to inform new WHO guidelines.
Impact Work ongoing
Start Year 2018
 
Description Gagandeep Kang-Christian Medical College 
Organisation Christian Medical College, Vellore
Country India 
Sector Academic/University 
PI Contribution Gastrointestinal Sciences. Statistical, epidemiological and mathematical analysis
Collaborator Contribution Clinical studies, immunological analysis
Impact multiple publications
Start Year 2010
 
Description Geshiaro 
Organisation Ethiopian Public Health Institute
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data, equipment and facilities
Impact No outputs yet.
Start Year 2018
 
Description Global Burden of disease 
Organisation Institute for Health Metrics and Evaluation (IHME)
Country United States 
Sector Charity/Non Profit 
PI Contribution Provided algorithms for the local burden of disease project
Collaborator Contribution Publications (3 in nature 1 in the New England Journal of Medicine, 1 in Lancet)
Impact Publications (3 in nature 1 in the New England Journal of Medicine, 1 in Lancet)
Start Year 2016
 
Description Greg Devine at QIMR Berghofer (Brisbane, Australia) 
Organisation QIMR Berghofer Medical Research Institute
Country Australia 
Sector Multiple 
PI Contribution Provide funding to run experiments in Australia on local Aedes mosquito populations
Collaborator Contribution Partner running experiments in Australia on local Aedes mosquito populations
Impact None yet
Start Year 2017
 
Description HIV Preventation Trial Network 
Organisation Fred Hutchinson Cancer Research Center (FHCRC)
Country United States 
Sector Charity/Non Profit 
PI Contribution A collaborative centre that develops and uses mathematical models to support HPTN research activities and inform research directions. We collaborate with: Statistical Centre for HIV/AIDS Research and Prevention.
Collaborator Contribution See above
Impact See publications, presentations and workshops on https://hptnmodelling.org/resources/
Start Year 2014
 
Description HIV prevention cascades 
Organisation Biomedical Research and Training Institute (BRTI)
Country Zimbabwe 
Sector Charity/Non Profit 
PI Contribution Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications.
Collaborator Contribution The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas.
Impact UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health
Start Year 2015
 
Description HIV prevention cascades 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS)
Country Global 
Sector Public 
PI Contribution Project leadership, project design, development of integrated HIV prevention cascade formulations, data collection, data analysis, and scientific publications.
Collaborator Contribution The Bill and Melinda Gates Foundation, LSHTM, Zimbabwe Ministry of Health and Child Care, and UNAIDS provided intellectual inputs into the development of the HIV prevention cascade formulations to be measured and interpreted in the study. BMGF also funded the study. Zimbabwe Ministry of Health and Child Care and Population Services International assisted with the establishment and provision of pre-exposure prophylaxis (PrEP) and voluntary medical male circumcision (VMMC) services in the study areas.
Impact UNAIDS draft guidelines on HIV prevention cascades Scientific publications: doi.org/10.1016/S2352-3018(16)30039-X doi.org/10.1007/s10461-018-2374-0 doi.org/10.1016/S2352-3018(18)30327-8 Collaboration is multi-disciplinary - epidemiology, demography, social science, public health
Start Year 2015
 
Description HIV rapid test misclassification errors 
Organisation University of Copenhagen
Department Department of Public Health
Country Denmark 
Sector Academic/University 
PI Contribution Research design, project management and coordination, staff recruitment, training and management, data processing and cleaning, data analysis, mathematical modelling, and report writing.
Collaborator Contribution The Zimbabwe Ministry of Health and Child Care gave permission for the study to be done as an extension to a round of national HIV surveillance and contributed to the study design, data collection and dissemination of results. US-CDC contributed to the study design and implementation and co-funded the underlying round of national HIV surveillance with the United Nations Global Fund for HIV, Malaria and TB control. Global Solutions for Infectious Disease developed and assisted in the implementation and interpretation of results obtained from a smartphone camera application used to identify poor quality outputs from HIV rapid tests and errors made by nursing staff in reading the output from these tests Researchers from the Universities of Copenhagen and Roehampton designed and led the implementation of the qualitative research components of the study BRTI provided a local institutional base in Zimbabwe from which to conduct the study
Impact Mathematical model data on the cost-effectiveness of repeat HIV testing prior to initiation on antiretroviral treatment for HIV Data on levels of false-positive and false-negative HIV test results occurring in routine HIV testing services in Zimbabwe Publication: doi.org/10.1093/cid/cix341 The outputs of the study to date contributed to increased adoption of a WHO recommendation to countries to carry out repeat HIV testing prior to initiating people living with HIV on antiretroviral therapy (including in Zimbabwe) Multi-disciplinary collaboration - epidemiology, demography, public health, mathematical modelling, social science, anthropology
Start Year 2015
 
Description HPRU Modelling 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution I am a theme lead for the HPRU in Modelling Methodology held by Neil Ferguson.
Collaborator Contribution Marc Baguelin (co-I for this MRC grant) is also a theme lead.
Impact None yet.
Start Year 2014
 
Description HPRU Respiratory Infections 
Organisation Public Health England
Country United Kingdom 
Sector Public 
PI Contribution I am a theme lead for Respiratory infections and will help to supervise staff at Imperial and PHE.
Collaborator Contribution They will also co supervise staff and helped to write the grant.
Impact None yet.
Start Year 2014
 
Description IMPPACT: Maximising the public health impact of interventions to control malaria in pregnancy 
Organisation Liverpool School of Tropical Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution To generate modelling and mapping of optimal preventative strategies for the prevention of malaria in pregnancy. These results were presented at Regional meetings of national policymakers in West and East Africa in Togo and Kenya respectively.
Collaborator Contribution Other partners were responsible for organising meetings, developing stakeholder interviews and translating results from recent trials into other policy-relevant recommendations and outputs.
Impact Multi-disciplinary: Modelling, Qualitative and Quantitive research, health economics and policy-making Regional meetings in Togo and Kenya Publication in PLoS Medicine and further publication pending.
Start Year 2015
 
Description IMPPACT: Maximising the public health impact of interventions to control malaria in pregnancy 
Organisation Sixth Framework Programme (FP6)
Department European and Developing Countries Clinical Trials Partnership
Country European Union (EU) 
Sector Public 
PI Contribution To generate modelling and mapping of optimal preventative strategies for the prevention of malaria in pregnancy. These results were presented at Regional meetings of national policymakers in West and East Africa in Togo and Kenya respectively.
Collaborator Contribution Other partners were responsible for organising meetings, developing stakeholder interviews and translating results from recent trials into other policy-relevant recommendations and outputs.
Impact Multi-disciplinary: Modelling, Qualitative and Quantitive research, health economics and policy-making Regional meetings in Togo and Kenya Publication in PLoS Medicine and further publication pending.
Start Year 2015
 
Description Information on a novel malaria transmission blocking vaccine candidate 
Organisation National Institutes of Health (NIH)
Department Vaccine Research Center (VRC)
Country United States 
Sector Public 
PI Contribution We are using mathematical models to predict the effectiveness of a novel vaccine candidate when used in a small scale field trial and in a wider mass distribution campaign.
Collaborator Contribution Provide details on the vaccine candidate including its efficacy and duration of protection.
Impact Predictive models that can support sample size calculations to adequately power studies.
Start Year 2019
 
Description Javier Martin (Dr) -NIBSC 
Organisation National Institute for Biological Standards and Control (NIBSC)
Country United Kingdom 
Sector Public 
PI Contribution Sequencing and analysis of polio virus in environmental samples
Collaborator Contribution Virus isolation and sequencing
Impact A supplement to the existing grant and a new grant
Start Year 2017
 
Description Jinan University 
Organisation Jinan University
Country China 
Sector Academic/University 
PI Contribution We will provide samples and analysis and Jinan will conduct immunological assays
Collaborator Contribution We will provide samples and analysis and Jinan will conduct immunological assays
Impact None yet
Start Year 2016
 
Description Kenya National Aid Control Council - Dr Nduku Kilonzo - Preparing for the double burden HIV 
Organisation Kenya National Malaria Control Programme
Country Kenya 
Sector Public 
PI Contribution Tim Hallett leads the research to inform policy
Collaborator Contribution Partners run the programme in Kenya
Impact A grant was obtained in 2017 and it is still active. Working on a manuscript.
Start Year 2014
 
Description Laval University 
Organisation University Hospital of Laval University
PI Contribution Collaborating with two teams lead by Michel Alary (HIV) and Marc Brisson (HPV Vaccination). I provide expetise in Modelling Statistical Analysis and Epidemiological expertise at the intersection between HIV and HPV.
Collaborator Contribution Michel Alary provides the epidemiological expertise and Marc Brisson provides modelling in health economic expertise.
Impact Multiple Publications and successful grant applications.
 
Description London Centre for NTD Research 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Collaborator Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Impact Scientific publicatons, public engagement events, network events, policy advocacy, facilitating research collaborations.
Start Year 2013
 
Description London Centre for NTD Research 
Organisation Natural History Museum
Country United Kingdom 
Sector Public 
PI Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Collaborator Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Impact Scientific publicatons, public engagement events, network events, policy advocacy, facilitating research collaborations.
Start Year 2013
 
Description London Centre for NTD Research 
Organisation Royal Veterinary College (RVC)
Country United Kingdom 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Collaborator Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Impact Scientific publicatons, public engagement events, network events, policy advocacy, facilitating research collaborations.
Start Year 2013
 
Description London Centre for NTD Research 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Collaborator Contribution expertise, intellectual input and the training of staff, equipment and facilities, data sharing, facilitation of collaboration
Impact Scientific publicatons, public engagement events, network events, policy advocacy, facilitating research collaborations.
Start Year 2013
 
Description MIT Broad Institute 
Organisation Broad Institute
Country United States 
Sector Charity/Non Profit 
PI Contribution Contribution of whole genome sequences of Cryptococcus neoformans, analysis and experimental data
Collaborator Contribution Contribution of whole genome sequences of Cryptococcus neoformans and analysis.
Impact Paper in submission
Start Year 2012
 
Description MRC Centre for Global Health Analysis - "Breaking silos and building collaborations for integrated and sustainable management of cholangiocarcinoma and its causal pathogen Opisthorchis viverrini in LMICs in the Lower Mekong Region 
Organisation International Agency for Research on Cancer (IARC)
Country France 
Sector Public 
PI Contribution PI
Collaborator Contribution co-I
Impact none yet
Start Year 2018
 
Description MRC Centre for Global Health Analysis - "Breaking silos and building collaborations for integrated and sustainable management of cholangiocarcinoma and its causal pathogen Opisthorchis viverrini in LMICs in the Lower Mekong Region 
Organisation Phramongkutklao College of Medicine
Country Thailand 
Sector Academic/University 
PI Contribution PI
Collaborator Contribution co-I
Impact none yet
Start Year 2018
 
Description Malaria in Pregnancy 
Organisation Liverpool School of Tropical Medicine
Country United Kingdom 
Sector Academic/University 
PI Contribution This collaboration involves estimating the burden of malaria in pregnancy, its relationship with transmission and the impact of interventions. I provide mathematical modelling expertise, data analysis to questions relevant to these issues.
Collaborator Contribution Members of the Malaria in Pregnancy Consortium Secretariat provide support for these analyses in terms of providing access to data and academic support and input. As well as providing funding for travel to meetings.
Impact I developed the first model of malaria in pregnancy (Walker et al, Nature Communications 2012) and its link to transmission and using this was able to develop the first map of potential low birth weight burden attributable to malaria (Walker et al, Lancet Global Health 2014). I am also part of a working group looking at the incremental impact of switching to a policy of testing pregnant women for malaria and treating them if infected (Incremental Screening and Treatment) relative to treating them presumptively which will provide scientific support to an Evidence Review Group which will report to the Malaria Policy Advisory Committee of the World Health Organisation about the potential area of application of this strategy. I provided a preliminary version of this analysis during a Malaria in Pregnancy symposium at ASTMH 2014 in New Orleans. Research from this collaboration was also presented at the Evidence Review Group meeting into Intermittent screening and treatment in pregnancy and the safety of ACTs in the first trimester at WHO in Geneva in July 2015 and had direct influence on WHO malaria in pregnancy policy.
Start Year 2014
 
Description Malaria mapping and burden 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution I provided supervision and worked collaboratively to produce malaria estimates for the global burden of disease project, the WHO and the global fund.
Collaborator Contribution Two subcontract grants, computational facilities, data preparation and synthesis, facility space at the Big data institute
Impact 2 papers submitted to the Lancet, 1 paper accepted in Nature
Start Year 2016
 
Description Malaria project collaborations 
Organisation Government of The Gambia
Country Gambia 
Sector Public 
PI Contribution Guide economic work packages
Collaborator Contribution co-production of research questions, data collection, analysis and dissemination
Impact Papers in press and preparation
 
Description Malaria project collaborations 
Organisation MURAZ Center
Country Burkina Faso 
Sector Academic/University 
PI Contribution Guide economic work packages
Collaborator Contribution co-production of research questions, data collection, analysis and dissemination
Impact Papers in press and preparation
 
Description Malaria project collaborations 
Organisation Medical Research Council (MRC)
Department MRC Unit, The Gambia
Country Gambia 
Sector Public 
PI Contribution Guide economic work packages
Collaborator Contribution co-production of research questions, data collection, analysis and dissemination
Impact Papers in press and preparation
 
Description Malaria project collaborations 
Organisation University of Bamako
Country Mali 
Sector Academic/University 
PI Contribution Guide economic work packages
Collaborator Contribution co-production of research questions, data collection, analysis and dissemination
Impact Papers in press and preparation
 
Description Malawi/Kenya 
Organisation Wellcome Trust
Department Malawi-Liverpool Wellcome Trust Clinical Research Programme
Country Malawi 
Sector Charity/Non Profit 
PI Contribution I recruited a Research Assistant from Malawi, on a UK Royal Society Global Challenges grant, in June 2017 to undertake modelling of the impact of intermittent treatment in pregnancy for malaria on drug resistance development. He worked for a year and a half working with me training in mathematical modelling.
Collaborator Contribution The partner hosted our postdoc for a number of months in Malawi, provided supervision and regular phone calls to discuss the progress of the project. They are also currently undertaking large trials of intermittent preventive treatment in pregnant women, and these trials helped to inform our modelling analysis.
Impact The RA recruited has now gone on to a PhD to LSHTM in the same field, which we hope will contribute to capacity building.
Start Year 2016
 
Description Mapping housing quality 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution A collaborative project mapping housing quality in Africa
Collaborator Contribution Research support, data assistance
Impact 1 paper accepted in Nature (article)
Start Year 2018
 
Description Mapping the risk of international infectious disease spread 
Organisation Healthsites.io
Country France 
Sector Private 
PI Contribution Developing a mathematical model of spatial spread of infectious diseases
Collaborator Contribution Providing data on Ebola
Impact Talks at several conferences Papers in preparation
Start Year 2016
 
Description Mapping the risk of international infectious disease spread 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Developing a mathematical model of spatial spread of infectious diseases
Collaborator Contribution Providing data on Ebola
Impact Talks at several conferences Papers in preparation
Start Year 2016
 
Description Medicines for Malaria Venture 
Organisation Medicines for Malaria Venture (MMV)
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution We are using mathematical modelling to estimate the impact of both existing antimalarial drugs and also products in development on malaria transmission, and their cost-effectiveness.
Collaborator Contribution Funding (research costs and 1 postdoc for 3 years), requests for research and advice on ongoing work.
Impact A data collaboration with the Worldwide Antimalarial Resistance Network and Sanofi Ltd to access clinical trial data. We published three papers: Nature Communications (2017), Malaria Journal (2017) and Trends in Parasitology (2017).
Start Year 2013
 
Description Member of Malaria Modelling Consortium 
Organisation Bill and Melinda Gates Foundation
Country United States 
Sector Charity/Non Profit 
PI Contribution I participated in consortium meetings, and contributed substantially to a Malaria Modelling Consortium report to the World Health Organization Malaria Policy Advisory Group on results from modelling mass drug administration for malaria control.
Collaborator Contribution Other modelling partners contribute modelling results, the Gates Foundation coordinate activities, arrange meetings and fund travel for the meetings.
Impact Malaria Modelling Consortium report to the World Health Organization Malaria Policy Advisory Group on results from modelling mass drug administration for malaria control. This is now published as a paper in Lancet Global Health.
Start Year 2015
 
Description Miren Iturizza-Gomara (Prof-Mrs) University of Liverpool 
Organisation University of Liverpool
Country United Kingdom 
Sector Academic/University 
PI Contribution Microbiome analysis
Collaborator Contribution Provide rotavirus
Impact 1 publication BMJ Open
Start Year 2018
 
Description Modelling and dengue vaccines 
Organisation Takeda Pharmaceutical Company
Department Takeda Global Research & Development Centre (Europe)
Country United Kingdom 
Sector Private 
PI Contribution Modelling related to Dengue disease and vaccination.
Collaborator Contribution Know how with regard to its therapeutic area vaccines and in particular, but limited to its Dengue, Norovirus and Polio candidate vaccines.
Impact N?A at this stage.
Start Year 2018
 
Description Modelling to support Kenya's National Strategic Plan for TB control 
Organisation Ministry of Health, Kenya
Country Kenya 
Sector Public 
PI Contribution Providing analysis and modelling in support of Kenya's upcoming National Strategic Plan for TB control
Collaborator Contribution Kenya's new national strategic plan will be used as a model by funding agencies such as the Global Fund, for applications by other countries. The modelling component of the strategic plan plays a key role in prioritisation amongst different interventions, and the Global Fund and other donors will require that other future applications are structured in the same way.
Impact Modelling input into National Strategic Plan, to be launched on World TB Day (24 Mar 2019) Work ongoing
Start Year 2017
 
Description NHIR emergency room demand 
Organisation Imperial College London
Department NIHR/Wellcome Trust Imperial Clinical Research Facility
Country United Kingdom 
Sector Public 
PI Contribution Assisting St Mary hospital and Charing-cross to predict A&E patient demand.
Collaborator Contribution Funding and data assistance (preparation and collection)
Impact None yet
Start Year 2018
 
Description NIH Pakistan 
Organisation National Institute of Health, Pakistan
Country Pakistan 
Sector Public 
PI Contribution Analyse data
Collaborator Contribution Provide sequence data and surveillance data
Impact None yet
Start Year 2016
 
Description NIRS Queensland 
Organisation QIMR Berghofer Medical Research Institute
Country Australia 
Sector Multiple 
PI Contribution Providing technical support and specialist knowledge
Collaborator Contribution Data and field expertise
Impact not known
Start Year 2017
 
Description NTD Modelling Consortium 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data.
Impact Scientific publications
Start Year 2015
 
Description NTD Modelling Consortium 
Organisation University of Warwick
Country United Kingdom 
Sector Academic/University 
PI Contribution expertise, intellectual input and the training of staff
Collaborator Contribution expertise, intellectual input and the training of staff, access to data.
Impact Scientific publications
Start Year 2015
 
Description PATH Innovation Collaboration - ANC-based surveillance tool 
Organisation Kenyan Institute for Medical Research (KEMRI)
Department KEMRI/CDC Research and Public Health Collaboration
Country Kenya 
Sector Public 
PI Contribution I am developing a statistical model using routine testing data from antenatal clinics in Western Kenya to estimate malaria transmission within the general population
Collaborator Contribution In-country collaborators PATH, Kenya Medical Research Institute and the US CDC are responsible for collecting, collating and providing the data, as well as organising dissemination workshops.
Impact A dissemination meeting took place in Kisumu in August 2018.
Start Year 2016
 
Description PATH Innovation Collaboration - ANC-based surveillance tool 
Organisation Program for Appropriate Technology in Health (PATH)
Country United States 
Sector Charity/Non Profit 
PI Contribution I am developing a statistical model using routine testing data from antenatal clinics in Western Kenya to estimate malaria transmission within the general population
Collaborator Contribution In-country collaborators PATH, Kenya Medical Research Institute and the US CDC are responsible for collecting, collating and providing the data, as well as organising dissemination workshops.
Impact A dissemination meeting took place in Kisumu in August 2018.
Start Year 2016
 
Description PATH to pilot novel bednet in pilot intervention trials 
Organisation PATH
Country Global 
Sector Private 
PI Contribution Provide technical support to help design a programme to monitor the efficacy and effectiveness of the introduction of a new type of bednet in Burkina Faso, Rwanda and Mozambique.
Collaborator Contribution Liaison with National Malaria Control Programmes and local partners to set up data collection and regulatory approval.
Impact Entomological and epidemiological data on the effectiveness of the Interceptor G2 bednet. Data on the ability of near infra-red spectroscopy for monitoring the age of mosquito populations.
Start Year 2018
 
Description PB-PG-0317-20039 - Uptake, effectiveness and acceptability of routine screening of pregnant migrants for latent tuberculosis infection in antenatal care: a feasibility study 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Economic analysis
Collaborator Contribution Collecting data
Impact None yet
Start Year 2019
 
Description Population Dynamics of Human Ascariasis 
Organisation University of Westminster
Country United Kingdom 
Sector Academic/University 
PI Contribution Data analysis, statistical and mathematical modelling through MRc-funded PhD student
Collaborator Contribution Sharing of data on chemo-expulsion studies of Ascaris lumbricoides in Bangladesh for the analysis and modelling of the population dynamics of ascariasis in human populations
Impact Publications, PubMed ID Number: 19208229; 20385140; 20620142
Start Year 2006
 
Description Population genomic statistical methods 
Organisation University of Oslo
Department Department of Oceanography
Country Norway 
Sector Academic/University 
PI Contribution Provided data analysis
Collaborator Contribution They provided software and statistical methods
Impact Software and publications
Start Year 2015
 
Description Prevention and Restriction on Anti Microbial Resistance AMR) in Pneumococci by Multi Level Modelling 
Organisation The Wellcome Trust Sanger Institute
Department MRC Centre for Genomics and Global Health, WTCHG and WTSI
Country United Kingdom 
Sector Academic/University 
PI Contribution Data analysis and lab work
Collaborator Contribution Data provision
Impact Multiple publications; sequenced data has emerged.Work ongoing on publication.
Start Year 2012
 
Description Research to Improve the Detection and Treatment of Latent Tuberculosis Infection (RID-TB) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Economic analysis
Collaborator Contribution Collecting data
Impact None yet
Start Year 2018
 
Description Respiratory infections sample collection 
Organisation Mahidol University
Country Thailand 
Sector Academic/University 
PI Contribution Data analysis
Collaborator Contribution Provide knowledge, data, samples and DNA
Impact Publications; sequenced data
Start Year 2012
 
Description Restriction modification analysis 
Organisation University of Leicester
Department University of Leicester, Proteomics facility
Country United Kingdom 
Sector Academic/University 
PI Contribution Provided strains, DNA and data analysis
Collaborator Contribution Provided techniques and new strains
Impact Publication and sequenced data
Start Year 2015
 
Description START-IPT study collaborator 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution We have produced models of Intermittent Preventive Treatment for malaria in school children, to assist the design of a trial and give an estimate of likely effect.
Collaborator Contribution Design and carrying out a cluster-randomized trial of Intermittent Preventive Treatment for malaria in school children in Uganda.
Impact Informed trial design. The collaboration is multi disciplinary, including mathematical modellers, clinicians, epidemiologists.
Start Year 2014
 
Description Sanofi data collaboration 
Organisation Sanofi
Country Global 
Sector Private 
PI Contribution We have carried out secondary analysis of trial data, to estimate the post-treatment prophylactic effect of artesunate amodiaquine.
Collaborator Contribution They contributed data.
Impact Publication draft in progress.
Start Year 2014
 
Description Sarah Cleveland - Glasgow 
Organisation University of Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution Centre Investigator, Christl Donnelly directly involved in the design and analysis of epidemological and ecological data relating to rabies control in Tanzania
Collaborator Contribution Provide data and ecological expertise 
Impact A PhD student, Sarah Hayes -SPH EPSRC scholarship
Start Year 2016
 
Description Sarah Cleveland and Katie Hampson- Glasgow 
Organisation University of Glasgow
Department MRC - University of Glasgow Centre for Virus Research
Country United Kingdom 
Sector Academic/University 
PI Contribution Centre Investigator, Christl Donnelly directly involved in the design and analysis of epidemological and ecological data relating to rabies control in Tanzania
Collaborator Contribution Provide data and ecological expertise 
Impact A PhD student, Sarah Hayes -SPH EPSRC scholarship
Start Year 2016
 
Description Set up of collaborative research partnership 
Organisation Clinton Health Access Initiative
Country United States 
Sector Charity/Non Profit 
PI Contribution Establishment of research collaboration and negotiation of data sharing agreement/materials transfer agreement with collaborators. (Swaziland National Malaria Control Programme).
Collaborator Contribution Agreement to enter into research collaboration and sharing of data for the purpose of this surveillance study. Negotiation of data transfer agreement/materials transfer agreement with collaborators.
Impact None as yet.
Start Year 2017
 
Description Set up of collaborative research partnership 
Organisation Government of Swaziland
Country Swaziland 
Sector Public 
PI Contribution Establishment of research collaboration and negotiation of data sharing agreement/materials transfer agreement with collaborators. (Swaziland National Malaria Control Programme).
Collaborator Contribution Agreement to enter into research collaboration and sharing of data for the purpose of this surveillance study. Negotiation of data transfer agreement/materials transfer agreement with collaborators.
Impact None as yet.
Start Year 2017
 
Description St Georges Hospital 
Organisation St George's University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Research into the genomics of Cryptococcal meningitis. Co-supervision of MRC PhD student
Collaborator Contribution Imperial College: Genomic analysis St Georges Hospital: Clinical trials, phenotypic analyses
Impact See publications list
 
Description Studies on Onchocerciasis-Associated Epilepsy 
Organisation University of Antwerp
Country Belgium 
Sector Academic/University 
PI Contribution Participation in First International Workshop on Onchocerciasis-Associated Epilepsy (OAE), University of Antwerp, October 2017; Chairing Symposium on OAE at the American Society of Tropical Medicine & Hygiene (ASTMH) annual meeting, New Orleans, October 2018; preparation of joint manuscripts
Collaborator Contribution Convening and organisation of First International Workshop on Onchocerciasis-Associated Epilepsy (OAE); coordination of the OAE Alliance; organisation of Symposium at ASTMH; drafting of joint manuscripts; submission of Organised Session on Morbidity Management and Disability Prevention for European Congress of Tropical Medicine and International Health (ECTMIH), Liverpool, September 2019
Impact Published manuscripts (e.g. in Infectious Diseases of Poverty) and manuscripts under review (e.g. in Frontiers in Neurology). Multidisciplinary collaboration: Neurologists; epidemiologists; physicians; social scientists.
Start Year 2017
 
Description The Broad Institute Genomics Collaboration 
Organisation Broad Institute
Country United States 
Sector Charity/Non Profit 
PI Contribution Whole Genome Sequencing and Analysis
Collaborator Contribution De Novo techniques for whole genome sequencing of Cryptococcus
Impact Manuscripts in preparation
Start Year 2014
 
Description The Global Fund 
Organisation Global Fund to Fight AIDS, Tuberculosis and Malaria
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution Modelling of scenarios to support the 2019 Investment Case
Collaborator Contribution Provided scenarios and input data
Impact Global Fund Investment Case: https://www.theglobalfund.org/en/news/2019-02-08-global-partners-commit-to-step-up-the-fight-against-aids-tb-and-malaria/
Start Year 2018
 
Description The farm environment: an overlooked reservoir of Mycobacterium bovis? 
Organisation University of Warwick
Department University of Warwick Research Students Skills Programme
Country Unknown 
Sector Academic/University 
PI Contribution Advising on sampling, analysis and interpretation of data, drafting manuscripts and reports
Collaborator Contribution Collecting samples, processing in the laboratory including control samples, drafting manuscripts and reports
Impact Conference presentations
Start Year 2016
 
Description Transmission Studies of Human Onchocerciasis in the Amazonian Focus 
Organisation Central University of Venezuela
Country Venezuela, Bolivarian Republic of 
Sector Academic/University 
PI Contribution Data analysis and preparation of joint publications
Collaborator Contribution Sharing of epidemiological, parasitological, and entomological data for the analysis of transmission and control studies of onchocerciasis in the Amazonian focus between Venezuela and Brazil
Impact We have published at least 14 papers in peer-review journals, a book chapter in Advances in Parasitology (2009), a book chapter in Encyclopaedia of Environmental Health (2011, 2013, 2019)
 
Description UCL-Lancet Countdown Climate Change and Health. 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Indicator lead - infectious diseases
Collaborator Contribution 26 international partner organisations.
Impact Annual Lancet publications Annual regional reports see: http://www.lancetcountdown.org/resources/
Start Year 2016
 
Description UNAIDS Reference Group on Estimates, Modelling, and Projections 
Organisation Avenir Health
PI Contribution - Co-chair activities of the UNAIDS Reference Group - Coordinate meetings of the UNAIDS Reference Group - Development of mathematical models and technical guidance to partners
Collaborator Contribution - Technical guidance on mathematical models, statistical methods, and data for estimation and projection of global HIV epidemic trends.
Impact - Multiple technical meetings: http://www.epidem.org/meetings - Multiple publications of related research: http://www.epidem.org/publications-reports - Methodological guidance on models and software used for global HIV epidemic estimates: https://avenirhealth.org/software-spectrum.php - Methodological guidance for global HIV estimates and projections published by UNAIDS: http://aidsinfo.unaids.org
 
Description UNAIDS Reference Group on Estimates, Modelling, and Projections 
Organisation Centers for Disease Control and Prevention (CDC)
Department Division of Global HIV/AIDS
Country Kenya 
Sector Public 
PI Contribution - Co-chair activities of the UNAIDS Reference Group - Coordinate meetings of the UNAIDS Reference Group - Development of mathematical models and technical guidance to partners
Collaborator Contribution - Technical guidance on mathematical models, statistical methods, and data for estimation and projection of global HIV epidemic trends.
Impact - Multiple technical meetings: http://www.epidem.org/meetings - Multiple publications of related research: http://www.epidem.org/publications-reports - Methodological guidance on models and software used for global HIV epidemic estimates: https://avenirhealth.org/software-spectrum.php - Methodological guidance for global HIV estimates and projections published by UNAIDS: http://aidsinfo.unaids.org
 
Description UNAIDS Reference Group on Estimates, Modelling, and Projections 
Organisation European Centre for Disease Prevention and Control (ECDC)
Country European Union (EU) 
Sector Public 
PI Contribution - Co-chair activities of the UNAIDS Reference Group - Coordinate meetings of the UNAIDS Reference Group - Development of mathematical models and technical guidance to partners
Collaborator Contribution - Technical guidance on mathematical models, statistical methods, and data for estimation and projection of global HIV epidemic trends.
Impact - Multiple technical meetings: http://www.epidem.org/meetings - Multiple publications of related research: http://www.epidem.org/publications-reports - Methodological guidance on models and software used for global HIV epidemic estimates: https://avenirhealth.org/software-spectrum.php - Methodological guidance for global HIV estimates and projections published by UNAIDS: http://aidsinfo.unaids.org
 
Description UNAIDS Reference Group on Estimates, Modelling, and Projections 
Organisation Global Fund to Fight AIDS, Tuberculosis and Malaria
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution - Co-chair activities of the UNAIDS Reference Group - Coordinate meetings of the UNAIDS Reference Group - Development of mathematical models and technical guidance to partners
Collaborator Contribution - Technical guidance on mathematical models, statistical methods, and data for estimation and projection of global HIV epidemic trends.
Impact - Multiple technical meetings: http://www.epidem.org/meetings - Multiple publications of related research: http://www.epidem.org/publications-reports - Methodological guidance on models and software used for global HIV epidemic estimates: https://avenirhealth.org/software-spectrum.php - Methodological guidance for global HIV estimates and projections published by UNAIDS: http://aidsinfo.unaids.org
 
Description UNAIDS Reference Group on Estimates, Modelling, and Projections 
Organisation Government of the United States of America
Department U.S. Census Bureau
Country Unknown 
Sector Public 
PI Contribution - Co-chair activities of the UNAIDS Reference Group - Coordinate meetings of the UNAIDS Reference Group - Development of mathematical models and technical guidance to partners
Collaborator Contribution - Technical guidance on mathematical models, statistical methods, and data for estimation and projection of global HIV epidemic trends.
Impact - Multiple technical meetings: http://www.epidem.org/meetings - Multiple publications of related research: http://www.epidem.org/publications-reports - Methodological guidance on models and software used for global HIV epidemic estimates: https://avenirhealth.org/software-spectrum.php - Methodological guidance for global HIV estimates and projections published by UNAIDS: http://aidsinfo.unaids.org
 
Description UNAIDS Reference Group on Estimates, Modelling, and Projections 
Organisation International Epidemiologic Databases to Evaluate AIDS (IeDEA)
Country Global 
Sector Charity/Non Profit 
PI Contribution - Co-chair activities of the UNAIDS Reference Group - Coordinate meetings of the UNAIDS Reference Group - Development of mathematical models and technical guidance to partners
Collaborator Contribution - Technical guidance on mathematical models, statistical methods, and data for estimation and projection of global HIV epidemic trends.
Impact - Multiple technical meetings: http://www.epidem.org/meetings - Multiple publications of related research: http://www.epidem.org/publications-reports - Methodological guidance on models and software used for global HIV epidemic estimates: https://avenirhealth.org/software-spectrum.php - Methodological guidance for global HIV estimates and projections published by UNAIDS: http://aidsinfo.unaids.org
 
Description UNAIDS Reference Group on Estimates, Modelling, and Projections 
Organisation Joint United Nations Programme on HIV/AIDS (UNAIDS)
Country Global 
Sector Public 
PI Contribution - Co-chair activities of the UNAIDS Reference Group - Coordinate meetings of the UNAIDS Reference Group - Development of mathematical models and technical guidance to partners
Collaborator Contribution - Technical guidance on mathematical models, statistical methods, and data for estimation and projection of global HIV epidemic trends.
Impact - Multiple technical meetings: http://www.epidem.org/meetings - Multiple publications of related research: http://www.epidem.org/publications-reports - Methodological guidance on models and software used for global HIV epidemic estimates: https://avenirhealth.org/software-spectrum.php - Methodological guidance for global HIV estimates and projections published by UNAIDS: http://aidsinfo.unaids.org
 
Description UNAIDS Reference Group on Estimates, Modelling, and Projections 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Department Alpha Network
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution - Co-chair activities of the UNAIDS Reference Group - Coordinate meetings of the UNAIDS Reference Group - Development of mathematical models and technical guidance to partners
Collaborator Contribution - Technical guidance on mathematical models, statistical methods, and data for estimation and projection of global HIV epidemic trends.
Impact - Multiple technical meetings: http://www.epidem.org/meetings - Multiple publications of related research: http://www.epidem.org/publications-reports - Methodological guidance on models and software used for global HIV epidemic estimates: https://avenirhealth.org/software-spectrum.php - Methodological guidance for global HIV estimates and projections published by UNAIDS: http://aidsinfo.unaids.org
 
Description UNAIDS Reference Group on Estimates, Modelling, and Projections 
Organisation UNICEF
Country Global 
Sector Public 
PI Contribution - Co-chair activities of the UNAIDS Reference Group - Coordinate meetings of the UNAIDS Reference Group - Development of mathematical models and technical guidance to partners
Collaborator Contribution - Technical guidance on mathematical models, statistical methods, and data for estimation and projection of global HIV epidemic trends.
Impact - Multiple technical meetings: http://www.epidem.org/meetings - Multiple publications of related research: http://www.epidem.org/publications-reports - Methodological guidance on models and software used for global HIV epidemic estimates: https://avenirhealth.org/software-spectrum.php - Methodological guidance for global HIV estimates and projections published by UNAIDS: http://aidsinfo.unaids.org
 
Description UNAIDS Reference Group on Estimates, Modelling, and Projections 
Organisation United Nations (UN)
Department UN Population Division
Country United States 
Sector Public 
PI Contribution - Co-chair activities of the UNAIDS Reference Group - Coordinate meetings of the UNAIDS Reference Group - Development of mathematical models and technical guidance to partners
Collaborator Contribution - Technical guidance on mathematical models, statistical methods, and data for estimation and projection of global HIV epidemic trends.
Impact - Multiple technical meetings: http://www.epidem.org/meetings - Multiple publications of related research: http://www.epidem.org/publications-reports - Methodological guidance on models and software used for global HIV epidemic estimates: https://avenirhealth.org/software-spectrum.php - Methodological guidance for global HIV estimates and projections published by UNAIDS: http://aidsinfo.unaids.org
 
Description UNAIDS Reference Group on Estimates, Modelling, and Projections 
Organisation United States President's Emergency Plan for AIDS Relief
Country United States 
Sector Public 
PI Contribution - Co-chair activities of the UNAIDS Reference Group - Coordinate meetings of the UNAIDS Reference Group - Development of mathematical models and technical guidance to partners
Collaborator Contribution - Technical guidance on mathematical models, statistical methods, and data for estimation and projection of global HIV epidemic trends.
Impact - Multiple technical meetings: http://www.epidem.org/meetings - Multiple publications of related research: http://www.epidem.org/publications-reports - Methodological guidance on models and software used for global HIV epidemic estimates: https://avenirhealth.org/software-spectrum.php - Methodological guidance for global HIV estimates and projections published by UNAIDS: http://aidsinfo.unaids.org
 
Description UNAIDS Reference Group on Estimates, Modelling, and Projections 
Organisation University of Cape Town
Department Centre for Infectious Disease Epidemiology and Research
Country South Africa 
Sector Academic/University 
PI Contribution - Co-chair activities of the UNAIDS Reference Group - Coordinate meetings of the UNAIDS Reference Group - Development of mathematical models and technical guidance to partners
Collaborator Contribution - Technical guidance on mathematical models, statistical methods, and data for estimation and projection of global HIV epidemic trends.
Impact - Multiple technical meetings: http://www.epidem.org/meetings - Multiple publications of related research: http://www.epidem.org/publications-reports - Methodological guidance on models and software used for global HIV epidemic estimates: https://avenirhealth.org/software-spectrum.php - Methodological guidance for global HIV estimates and projections published by UNAIDS: http://aidsinfo.unaids.org
 
Description University of Hong Kong 
Organisation University of Hong Kong
Country Hong Kong 
Sector Academic/University 
PI Contribution Collaboration on fieldwork and analysis
Collaborator Contribution Helped to win grants and publish papers
Impact Numerous publications with Cowling or Kwok as co authors.
Start Year 2010
 
Description Vaccine Efficacy Evaluation for Priority Emerging Diseases (VEEPED) 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Principal Investigator on grant, leading the team at Imperial College Trial design and expertise, writing manuscripts
Collaborator Contribution LSHTM is leading the project Trial design, integration of modelling results, epidemiology & ethical considerations to come up with vaccine trial and policy recommendations, writing manuscripts
Impact No outputs as yet
Start Year 2018
 
Description Vaccine Efficacy Evaluation for Priority Emerging Diseases (VEEPED) 
Organisation University of Oxford
Department Ruskin School of Drawing and Fine Art
Country Unknown 
Sector Academic/University 
PI Contribution Principal Investigator on grant, leading the team at Imperial College Trial design and expertise, writing manuscripts
Collaborator Contribution LSHTM is leading the project Trial design, integration of modelling results, epidemiology & ethical considerations to come up with vaccine trial and policy recommendations, writing manuscripts
Impact No outputs as yet
Start Year 2018
 
Description Vaccine Efficacy Evaluation for Priority Emerging Diseases (VEEPED) 
Organisation University of Warwick
Department University of Warwick Research Students Skills Programme
Country Unknown 
Sector Academic/University 
PI Contribution Principal Investigator on grant, leading the team at Imperial College Trial design and expertise, writing manuscripts
Collaborator Contribution LSHTM is leading the project Trial design, integration of modelling results, epidemiology & ethical considerations to come up with vaccine trial and policy recommendations, writing manuscripts
Impact No outputs as yet
Start Year 2018
 
Description Vaccine design using ecological models 
Organisation Simon Fraser University
Country Canada 
Sector Academic/University 
PI Contribution Data analysis and models
Collaborator Contribution Provided machine learning techniques and vaccine design
Impact Patent and publication under preparation
Start Year 2017
 
Description Vaccine immune responses 
Organisation Antigen Discovery Inc
Country United States 
Sector Private 
PI Contribution Data analysis and designed an assay
Collaborator Contribution Data provision
Impact Multiple publications and data released on vaccine trial
Start Year 2014
 
Description WHO - Global Influenza programme 
Organisation World Health Organization (WHO)
Country Global 
Sector Public 
PI Contribution Coordinate network of scientists and provide analysis
Collaborator Contribution Provide policy questions and improve data access
Impact Teleconference calls between modelling group country, epidemiologists and WHO
Start Year 2017
 
Description WHO - Vaccination against STI 
Organisation World Health Organization (WHO)
Department South Sudan World Health Organization
Country Global 
Sector Public 
PI Contribution Expertise in Mathematical Modelling WHO efforts for the elimination of cervical cancer globally. We collaborate on another project on HSV 2 disease burden and vaccination impact to inform WHO business case for the development of a new vaccine.
Collaborator Contribution They partially fund some of the research and the provide scientific input.
Impact Multiple publications, workshops and we contribute to inform global strategy
Start Year 2017
 
Description WHO - Vaccines for public health emergencies (FWC/IVB/IVR/IMR) 
Organisation World Health Organization (WHO)
Country Global 
Sector Public 
PI Contribution Work is still on-going. To produce a WHO blueprint, statistical and epidemiological design and analysis plan.
Collaborator Contribution Contributions to the design and plan for analysis of vaccine studies during public health emergencies.
Impact Two papers submitted for WHO- Vaccines for public health emergencies Natalie E. Dean1*, Pierre-Stéphane Gsell2, Ron Brookmeyer3, Victor De Gruttola4, Christl A. Donnelly5, M. Elizabeth Halloran6,7, Momodou Jasseh8, Martha Nason9, Ximena Riveros2, Conall Watson10, Ana Maria Henao-Restrepo2, Ira M. Longini, Jr.1* Considerations for the design of vaccine efficacy trials during public health emergencies. In press (Science Translational Medicine) Natalie E. Dean1*, Ira M. Longini, Jr1, Ron Brookmeyer2, Christl A. Donnelly3, M. Elizabeth Halloran4,5, Pierre-Stéphane Gsell6, Peter W. Horby7, Martha C. Nason8, Victor De Gruttola9* Combining evidence from randomized clinical trials across outbreaks. Under review with Clinical Infectious Diseases.
Start Year 2016
 
Description WHO Global Influenza 
Organisation World Health Organization (WHO)
Department Global Influenza Programme
Country Switzerland 
Sector Public 
PI Contribution Helped to set up an international analytics working group to analyse seasonal influenza data reported by Member states to WHO. Continue to be involved in organising fortnightly teleconferences and assist in meetings.
Collaborator Contribution Curation of data for analysis, platform for fortnightly calls, organisation of international meetings.
Impact Influenza Public Health Research Agenda, Pandemic Influenza Severity Assessment Analytics white paper, draft opinion piece prepared for submission to peer-reviewed journal.
Start Year 2017
 
Description WHO Global Malaria Programme 
Organisation World Health Organization (WHO)
Department Global Malaria Programme
Country Switzerland 
Sector Charity/Non Profit 
PI Contribution Collaboration on modelling to inform policy across a range of areas, including new products and economics.
Collaborator Contribution Intellectual partners, developing questions relevant to support public health policy.
Impact PMID: 29242750
Start Year 2011
 
Description WHO IVR Dengue 
Organisation World Health Organization (WHO)
Department Initiative for Vaccine Research
Country Switzerland 
Sector Public 
PI Contribution Technical assistance regarding serosurvey design for targeting the dengue vaccine.
Collaborator Contribution Expertise, external collaborators, platform for public reports.
Impact Public report, publication in peer-reviewed journal "Considerations for Serosurvey Design", PLoS One/
Start Year 2016
 
Description WHO Outbreak Analysis 
Organisation World Health Organization (WHO)
Department Department of Pandemic and Epidemic Diseases
Country Global 
Sector Public 
PI Contribution We continue to be a WHO Collaborating Centre for Infectious Disease Modelling and as part of the Terms of Reference contributed rapid analysis of outbreaks and epidemics. We rapidly evaluate the epidemiology and transmission dynamics of emerging and re-emerging threats. 2018 - 2019 has included analysis of the Ebola outbreak(s) in the Democratic Republic of the Congo, providing >15 reports for WHO and the Ministry of Health.
Collaborator Contribution Data for analysis, collaborations with country MoH.
Impact Over 20 reports for internal use at WHO and Country level. Publication in peer-reviewed journal.
Start Year 2010
 
Description YZ-UHP! 
Organisation Biomedical Research and Training Institute (BRTI)
Country Zimbabwe 
Sector Charity/Non Profit 
PI Contribution Project leadership, securing funding, research design (including drafting of study questionnaires and research and intervention tools), organising data collection, data processing systems development and implementation, support with staff training, statistical data analysis, mathematical modelling, and report writing.
Collaborator Contribution BRTI - provision of a local institutional research base for the study; intellectual inputs to funding proposal development and research design, data collection and data processing systems, and scientific reports; local consultations on draft research tools; translation of research tools into the local language; obtained local IRB approvals; conducting data collection including implementation of behavioural economics interventions; local supervision of the local partner (DOMCCP) responsible for implementing the community psychology intervention; quality assurance for field-based HIV diagnostics. LSE - intellectual leadership on the design and oversight of behavioural economics interventions and associated research and intervention tools. University of Copenhagen - intellectual leadership on the design and oversight of the community psychology intervention and the qualitative research components of the study and of the associated research and intervention tools. ZMOHCC and PSI - support with establishing PrEP and VMMC services in the study areas. DOMCCP - implementation of the community psychology intervention. AiBST - laboratory diagnostics for detection of PrEP in dried blood spot specimens. AHISA Alliance - as a result of this project, Dr Constance Nyamukapa (Research Associate), Dr Owen Mugurungi (Director of the AIDS and TB Department in ZMOHCC) and myself were invited and were successful in becoming members of the NIH-supported Adolescent HIV Prevention and Treatment Implementation Science Alliance
Impact No outputs as yet Collaboration is multi-disciplinary - epidemiology, behavioural economics, demography, community psychology, laboratory diagnostics, public health
Start Year 2017
 
Description YZ-UHP! 
Organisation Ministry of Health and Child Welfare of the Republic of Zimbabwe
Country Zimbabwe 
Sector Public 
PI Contribution Project leadership, securing funding, research design (including drafting of study questionnaires and research and intervention tools), organising data collection, data processing systems development and implementation, support with staff training, statistical data analysis, mathematical modelling, and report writing.
Collaborator Contribution BRTI - provision of a local institutional research base for the study; intellectual inputs to funding proposal development and research design, data collection and data processing systems, and scientific reports; local consultations on draft research tools; translation of research tools into the local language; obtained local IRB approvals; conducting data collection including implementation of behavioural economics interventions; local supervision of the local partner (DOMCCP) responsible for implementing the community psychology intervention; quality assurance for field-based HIV diagnostics. LSE - intellectual leadership on the design and oversight of behavioural economics interventions and associated research and intervention tools. University of Copenhagen - intellectual leadership on the design and oversight of the community psychology intervention and the qualitative research components of the study and of the associated research and intervention tools. ZMOHCC and PSI - support with establishing PrEP and VMMC services in the study areas. DOMCCP - implementation of the community psychology intervention. AiBST - laboratory diagnostics for detection of PrEP in dried blood spot specimens. AHISA Alliance - as a result of this project, Dr Constance Nyamukapa (Research Associate), Dr Owen Mugurungi (Director of the AIDS and TB Department in ZMOHCC) and myself were invited and were successful in becoming members of the NIH-supported Adolescent HIV Prevention and Treatment Implementation Science Alliance
Impact No outputs as yet Collaboration is multi-disciplinary - epidemiology, behavioural economics, demography, community psychology, laboratory diagnostics, public health
Start Year 2017
 
Description YZ-UHP! 
Organisation Population Services International
Department Society for Family Health
Country South Africa 
Sector Charity/Non Profit 
PI Contribution Project leadership, securing funding, research design (including drafting of study questionnaires and research and intervention tools), organising data collection, data processing systems development and implementation, support with staff training, statistical data analysis, mathematical modelling, and report writing.
Collaborator Contribution BRTI - provision of a local institutional research base for the study; intellectual inputs to funding proposal development and research design, data collection and data processing systems, and scientific reports; local consultations on draft research tools; translation of research tools into the local language; obtained local IRB approvals; conducting data collection including implementation of behavioural economics interventions; local supervision of the local partner (DOMCCP) responsible for implementing the community psychology intervention; quality assurance for field-based HIV diagnostics. LSE - intellectual leadership on the design and oversight of behavioural economics interventions and associated research and intervention tools. University of Copenhagen - intellectual leadership on the design and oversight of the community psychology intervention and the qualitative research components of the study and of the associated research and intervention tools. ZMOHCC and PSI - support with establishing PrEP and VMMC services in the study areas. DOMCCP - implementation of the community psychology intervention. AiBST - laboratory diagnostics for detection of PrEP in dried blood spot specimens. AHISA Alliance - as a result of this project, Dr Constance Nyamukapa (Research Associate), Dr Owen Mugurungi (Director of the AIDS and TB Department in ZMOHCC) and myself were invited and were successful in becoming members of the NIH-supported Adolescent HIV Prevention and Treatment Implementation Science Alliance
Impact No outputs as yet Collaboration is multi-disciplinary - epidemiology, behavioural economics, demography, community psychology, laboratory diagnostics, public health
Start Year 2017
 
Description YZ-UHP! 
Organisation The African Institute of Biomedical Science and Technology
PI Contribution Project leadership, securing funding, research design (including drafting of study questionnaires and research and intervention tools), organising data collection, data processing systems development and implementation, support with staff training, statistical data analysis, mathematical modelling, and report writing.
Collaborator Contribution BRTI - provision of a local institutional research base for the study; intellectual inputs to funding proposal development and research design, data collection and data processing systems, and scientific reports; local consultations on draft research tools; translation of research tools into the local language; obtained local IRB approvals; conducting data collection including implementation of behavioural economics interventions; local supervision of the local partner (DOMCCP) responsible for implementing the community psychology intervention; quality assurance for field-based HIV diagnostics. LSE - intellectual leadership on the design and oversight of behavioural economics interventions and associated research and intervention tools. University of Copenhagen - intellectual leadership on the design and oversight of the community psychology intervention and the qualitative research components of the study and of the associated research and intervention tools. ZMOHCC and PSI - support with establishing PrEP and VMMC services in the study areas. DOMCCP - implementation of the community psychology intervention. AiBST - laboratory diagnostics for detection of PrEP in dried blood spot specimens. AHISA Alliance - as a result of this project, Dr Constance Nyamukapa (Research Associate), Dr Owen Mugurungi (Director of the AIDS and TB Department in ZMOHCC) and myself were invited and were successful in becoming members of the NIH-supported Adolescent HIV Prevention and Treatment Implementation Science Alliance
Impact No outputs as yet Collaboration is multi-disciplinary - epidemiology, behavioural economics, demography, community psychology, laboratory diagnostics, public health
Start Year 2017
 
Description YZ-UHP! 
Organisation University of Copenhagen
Department Psychiatric Center Copenhagen
Country Denmark 
Sector Academic/University 
PI Contribution Project leadership, securing funding, research design (including drafting of study questionnaires and research and intervention tools), organising data collection, data processing systems development and implementation, support with staff training, statistical data analysis, mathematical modelling, and report writing.
Collaborator Contribution BRTI - provision of a local institutional research base for the study; intellectual inputs to funding proposal development and research design, data collection and data processing systems, and scientific reports; local consultations on draft research tools; translation of research tools into the local language; obtained local IRB approvals; conducting data collection including implementation of behavioural economics interventions; local supervision of the local partner (DOMCCP) responsible for implementing the community psychology intervention; quality assurance for field-based HIV diagnostics. LSE - intellectual leadership on the design and oversight of behavioural economics interventions and associated research and intervention tools. University of Copenhagen - intellectual leadership on the design and oversight of the community psychology intervention and the qualitative research components of the study and of the associated research and intervention tools. ZMOHCC and PSI - support with establishing PrEP and VMMC services in the study areas. DOMCCP - implementation of the community psychology intervention. AiBST - laboratory diagnostics for detection of PrEP in dried blood spot specimens. AHISA Alliance - as a result of this project, Dr Constance Nyamukapa (Research Associate), Dr Owen Mugurungi (Director of the AIDS and TB Department in ZMOHCC) and myself were invited and were successful in becoming members of the NIH-supported Adolescent HIV Prevention and Treatment Implementation Science Alliance
Impact No outputs as yet Collaboration is multi-disciplinary - epidemiology, behavioural economics, demography, community psychology, laboratory diagnostics, public health
Start Year 2017
 
Description Zika - Institut Pasteur 
Organisation Pasteur Institute, Paris
Country France 
Sector Academic/University 
PI Contribution Investigators from the MRC Centre for Outbreak Analysis and Modelling designed the collaboration and are now overseeing it.
Collaborator Contribution Training of lab techniques and provision of reagents.
Impact None yet but we are working on publications
Start Year 2016
 
Description Zika - University of Wisconsin (still active) 
Organisation University of Wisconsin-Madison
Country United States 
Sector Academic/University 
PI Contribution Investigators designed the collaboration and are now overseeing it.
Collaborator Contribution Serological surveys, fieldwork, and testing.
Impact None yet but we are working on publications
Start Year 2016
 
Title BE - PrEP 
Description Tablet-based game to improve HIV risk perception, provide information on pre-exposure prophylaxis for HIV prevention (PrEP), and offer referrals to local PrEP services. The intervention is currently being pre-tested in a longitudinal population-based survey in Manicaland, east Zimbabwe. 
Type Preventative Intervention - Behavioural risk modification
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2018
Development Status Under active development/distribution
Impact NA 
 
Title BE - PrEP adherence 
Description SMS text reminders to women who have taken up pre-exposure prophylaxis (PrEP) to strengthen their adherence to PrEP. The intervention is currently being pre-tested in a longitudinal population-based survey in Manicaland, east Zimbabwe. 
Type Preventative Intervention - Behavioural risk modification
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2018
Development Status Under active development/distribution
Impact NA 
 
Title BE - VMMC 
Description Behavioural economics theory-based game to improve HIV risk perception, provide information on voluntary medical male circumcision, and offer referrals to local VMMC services with a financial incentive to take up VMMC. Participants are randomised to receive a fixed or a lottery-based incentive. The intervention is currently being pre-tested in a longitudinal population-based survey in Manicaland, east Zimbabwe. 
Type Preventative Intervention - Behavioural risk modification
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2018
Development Status Under active development/distribution
Impact NA 
 
Title Community conversations 
Description Community conversations to build support from key family members, peers and the wider community for adolescent girls and young women (AGYW) to use HIV prevention methods to protect themselves from HIV infection. Modest funding is provided to community groups to help them implement activities to identify and address social and practical barriers to use of HIV prevention methods by AGYW and their male partners. The intervention is currently being pre-tested in a longitudinal population-based survey in Manicaland, east Zimbabwe, as an intervention to complement the individual-level behavioural economics PrEP and VMMC interventions described elsewhere. 
Type Preventative Intervention - Behavioural risk modification
Current Stage Of Development Early clinical assessment
Year Development Stage Completed 2018
Development Status Under active development/distribution
Impact NA 
 
Title EpiEstim 
Description Package for the R statistical software to estimate reproduction number during an epidemic. We created an updated version of a software we initially developed in 2013, with more flexibility in the method and a user friendly interface 
Type Of Technology Software 
Year Produced 2019 
Open Source License? Yes  
Impact One paper in preparation 
URL https://github.com/jstockwin/EpiEstimApp
 
Title Epiflows 
Description Epiflows is an R package for risk assessment of travel-related spread of disease. It produces estimates of the expected number of symptomatic and/or asymptomatic infections that could be introduced to other locations from the source of infection. 
Type Of Technology Software 
Year Produced 2018 
Open Source License? Yes  
Impact Publication: https://f1000research.com/articles/7-1374/v1 
URL https://github.com/reconhub/epiflows
 
Title HPCs-portal 
Description Portal to track progress with implementing data collection and individual-level intervention procedures for a study measuring and interpreting HIV prevention cascades and investigating multilevel factors influencing why adolescent girls and young women don't use efficacious HIV prevention methods in east Zimbabwe. 
Type Of Technology Webtool/Application 
Year Produced 2018 
Open Source License? Yes  
Impact Improved oversight, management and implementation of the survey and intervention procedures including real-time monitoring of progress against targets and data quality for key aspects of the study. 
URL https://portal.yzuhp.co.zw
 
Title Outbreaks 
Description This package compiles a series of publicly available disease outbreak data. Data can be provided as R objects (loaded automatically when loading the package), text files distributed alongside the package, or functions generating a dataset. 
Type Of Technology Software 
Year Produced 2016 
Open Source License? Yes  
Impact Several publications, including: https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1006554 
URL https://github.com/reconhub/outbreaks
 
Title PhyDyn 
Description Phylogenetic and Phylodynamic Inference 
Type Of Technology Software 
Year Produced 2018 
Open Source License? Yes  
Impact PhyDyn - First public release 
URL https://github.com/mrc-ide/PhyDyn
 
Title PopPUNK 
Description It is a bacterial genomic epidemiology software 
Type Of Technology Software 
Year Produced 2018 
Open Source License? Yes  
Impact Publication and development of a new typing scheme for pneumococcus 
URL https://poppunk.readthedocs.io/en/latest
 
Title Publication relating to the software epiflows which is published in F1000Research 
Description Publication relating to the software epiflows which is published in F1000Research https://f1000research.com/articles/7-1374/v1 
Type Of Technology Software 
Year Produced 2018 
Open Source License? Yes  
Impact Not yet known 
URL https://f1000research.com/articles/7-1374/v1
 
Title RDTs-Smartphone camera app 
Description Smartphone camera application developed by our collaborators on the study on HIV misclassification errors (Global Solutions for Infectious Diseases) to collect and transmit images of the outputs from HIV rapid tests used in routine health services - thereby enabling evaluation by external experts of the quality of outputs from these tests and the accuracy of interpretation of these outputs by local clinic staff. 
Type Of Technology Software 
Year Produced 2016 
Open Source License? Yes  
Impact The tool has enabled us to establish that approximately 50% of false-negative HIV test results occurring in routine health services in Zimbabwe could be due to errors by local clinic staff in reading or recording the outputs from HIV rapid tests. 
 
Title Skygrowth 
Description Phylodynamic Inference 
Type Of Technology Software 
Year Produced 2018 
Open Source License? Yes  
Impact Skygrowth- 1 publication in Systematic Biology New version released 
URL https://github.com/mrc-ide/skygrowth
 
Title Treedater 
Description Phylogenetics 
Type Of Technology Software 
Year Produced 2018 
Open Source License? Yes  
Impact Treedater- 1 pub in Virus Evolution New version released 
URL https://github.com/emvolz/treedater
 
Title rdhs: API Client and Dataset Management for the Demographic and Health Survey (DHS) Data 
Description Provides a client for (1) querying the DHS API for survey indicators and metadata (), (2) identifying surveys and datasets for analysis, (3) downloading survey datasets from the DHS website, (4) loading datasets and associate metadata into R, and (5) extracting variables and combining datasets for pooled analysis. 
Type Of Technology Software 
Year Produced 2019 
Open Source License? Yes  
Impact - Published and maintained rOpenSci foundation 
URL https://ropensci.github.io/rdhs/
 
Title vimes 
Description Package for the R statistical software to detect outbreak clusters 
Type Of Technology Software 
Year Produced 2018 
Open Source License? Yes  
Impact One article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312344/ Starting a collaboration with Public Health England and one with Santé Publique France to implement software on their surveillance data 
URL https://github.com/reconhub/vimes
 
Company Name R Epidemics Consortium 
Description The R Epidemics Consortium (RECON) is international not-for-profit, non-governmental organisation gathering experts in data science, modelling methodology, public health, and software development to create the next generation of analytics tools for informing the response to disease outbreaks, health emergencies and humanitarian crises, using the R software and other free, open-source resources. This includes packages specifically designed for handling, visualising, and analysing outbreak data using cutting-edge statistical methods, as well as more general-purpose tools for data cleaning, versioning, and encryption, and system infrastructure. 
Year Established 2018 
Impact Training - short courses and hackathons Release of open-source projects and packages
Website https://www.repidemicsconsortium.org/
 
Description Royal Society Diversity Conference: Achieving diverse leadership in a research environment (01/11/2018) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact The panel brought high-profile speakers from STEM academia and industry to share their expertise in creating inclusive leadership teams and overcoming barriers to success. The conference was of particular interest to the research community, scientists, diversity practitioners, learned academies and societies, professional bodies and policy-makers.
Year(s) Of Engagement Activity 2018
URL https://royalsociety.org/science-events-and-lectures/2018/11/annual-diversity-conference-2018/
 
Description A glass of wine and some evidence synthesis (Christl Donnelly) 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Article for Royal Society's policy blog
Year(s) Of Engagement Activity 2018
URL https://blogs.royalsociety.org/in-verba/2018/06/22/evidencesynthesis/
 
Description ASTMH 2018 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Poster presentation on dengue transmission intensity in Colombia, American Society of Tropical Medicine and Hygiene Conference 2018.
Year(s) Of Engagement Activity 2018
 
Description An Innovative Research Collaboration: Selected Research Highlights 2019 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact LCNTDR's new research booklet 'An Innovative Research Collaboration: Selected Research Highlights 2019' (PDF 6MB) contains 16 articles in which the researchers provide a non-technical introduction to their research. Each article outlines the background, need and impact of the research project.
Year(s) Of Engagement Activity 2019
URL https://www.londonntd.org/news/an-innovative-research-collaboration-selected-research-highlights-201...
 
Description Article for Biomedical Science Journal for Teens 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Schools
Results and Impact Worked with Science Journal for Kids to produce an accessible article with assessment questions and teachers' key aimed at a teenage audience
Year(s) Of Engagement Activity 2018
URL https://www.sciencejournalforkids.org/search-articles/category/ebola
 
Description Capacity building Ethiopia 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Introduction of the new collaborative project with goals for the next 5 years for partners and policy makers.
Year(s) Of Engagement Activity 2018
 
Description Developed an educational tool 'An infectious way to teach students about outbreaks' 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Postgraduate students
Results and Impact The study of infectious disease outbreaks is required to train today's epidemiologists. A typical way to introduce and explain key epidemiological concepts is through the analysis of a historical outbreak. There are, however, few training options that explicitly utilise real-time simulated stochastic outbreaks where the participants themselves comprise the dataset they subsequently analyse. In our activity, we presented a teaching exercise in which an infectious disease outbreak is simulated over a five-day period and subsequently analysed. We iteratively developed the teaching exercise to offer additional insight into analysing an outbreak. An R package for visualisation, analysis and simulation of the outbreak data was developed to accompany the practical to reinforce learning outcomes. Computer simulations of the outbreak revealed deviations from observed dynamics, highlighting how simplifying assumptions conventionally made in mathematical models often differ from reality. Our activity provides a pedagogical tool for others to use and adapt in their own settings.
Year(s) Of Engagement Activity 2016,2017,2018
URL https://www.sciencedirect.com/science/article/pii/S1755436517300920?via%3Dihub
 
Description Edinburgh Science Festival 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Ticketed event at the Edinburgh Science Festival, public presentation + panel discussion. Generated public discussion, debate, education, awareness.
Year(s) Of Engagement Activity 2018
URL https://www.sciencefestival.co.uk/
 
Description Epirecipes (Thibaut Jombart) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact This was a three day meeting to bring together researchers to implement as many different epidemiological models as possible. The meeting was held at The Alan Turing Institute on Monday 1st October 2018
Year(s) Of Engagement Activity 2018
URL http://epirecip.es/
 
Description Evidence Synthesis Policy work - article in Blog (22/06/2018) 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Royal Society and the Academy of Medical Sciences publication
Donnelly C and Kreitmair M. A glass of wine and some evidence synthesis - In Verba Royal Society blog.
https://blogs.royalsociety.org/in-verba/2018/06/22/evidencesynthesis/
https://royalsociety.org/topics-policy/projects/evidence-synthesis/
Year(s) Of Engagement Activity 2018
URL https://blogs.royalsociety.org/in-verba/2018/06/22/evidencesynthesis/
 
Description Flu Frenzy 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact We ran a influenza epidemic simulation for school children 15 - 17 years old through a 1/2 day workshop.
The aims were to familiarise students with the concept of epidemiology, our research and career, and infectious disease parameters.
Year(s) Of Engagement Activity 2018
 
Description HPCs-stakeholders meeting 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Professional Practitioners
Results and Impact Presentation and discussion of proposed integrated formulations for HIV prevention cascades for use in evaluating and strengthening implementation of HIV prevention methods. The presentations sparked discussion and ideas for simplification and improvements to the proposed formulations.
Year(s) Of Engagement Activity 2017
 
Description HPCs-workshop 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Workshop to produce improved formulations of HIV prevention cascades that meet the needs of policymakers and practitioners engaged in HIV prevention at international, national and local levels. The formulations developed at the workshop were subsequently presented at an international stakeholders meeting organised by UNAIDS in Geneva and were used in the development of international guidelines that have ow been drafted by UNAIDS for use by countries in sub-Saharan Africa.
Year(s) Of Engagement Activity 2017
 
Description Hackfest (Thibaut Jomnbart) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Hackfest 1, London 2017, Making outbreak analysis easier and prettier
Hackfest 2, London 2017, Mapping epidemics
Hackfest 3, Malta 2018, SitReps and Case Studies; 2 day interactive workshop where participants can bring their data, problems and questions, and go back home with a customised case study or sitrep, using state-of-the art analysis tools.
Year(s) Of Engagement Activity 2017,2018
 
Description How to eliminate rabies: why vaccinating man's best friend is man's best hope (06/12/2018) 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Public/other audiences
Results and Impact Article written by C. Donnelly
Year(s) Of Engagement Activity 2018
URL https://www.londonntd.org/news/how-to-eliminate-rabies-why-vaccinating-man%E2%80%99s-best-friend-is-...
 
Description How to eliminate rabies: why vaccinating man's best friend is man's best hope (Christl Donnelly) 
Form Of Engagement Activity Engagement focused website, blog or social media channel
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Public/other audiences
Results and Impact Article on Imperial Medicine Blog as part of World Rabies Day in 2017, new version published on London Centre for Neglected Tropical Diseases Research news website
Year(s) Of Engagement Activity 2017,2018
URL https://wwwf.imperial.ac.uk/blog/imperial-medicine/2017/09/28/world-rabies-day-why-vaccinating-mans-...
 
Description Introduction to Infectious Disease Modelling, Johannesburg, South Africa (Thibaut Jombart) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Three-day workshop, 21-23 May 2018
Year(s) Of Engagement Activity 2018
 
Description Introduction to R for surveillance and outbreak analysis, Sofia, Bulgaria (Thibaut Jombart) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Four-day short course, to provide an introduction to surveillance and outbreak analysis using the R software at SoHo workspace in Sofia Bulgaria, 8-11 October 2018. Participants will get an introduction and overview of conducting epidemiological analyses in R and gain practical experience of new packages for outbreak analysis developed by RECON, including descriptive approaches (epicurves), single- and multi-variable analyses (in the context of outbreak investigations) and depending on participant feedback phylogenetic analyses using R, short-term forecasting or automated sitrep generation.
Year(s) Of Engagement Activity 2018
URL https://recon-sofia-2018.netlify.com/
 
Description Introduction to outbreak analysis using R, Malta (Thibaut Jombart) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Two-day short course to provide an introduction to outbreak analysis using the R software in the Mater Dei Hospital Malta, 19-20 November 2018, as a satellite event to the ESCAIDE conference. The workshop was aimed at people currently undertaking, or having recently completed, a field-epidemiology training programme (FETP), with some interest in epidemics analysis using R. Participants will get an overview and gain practical experience of new packages for outbreak analysis developed by RECON, including descriptive approaches (epicurves), short-term forecasting, or automated sitrep generation.
Year(s) Of Engagement Activity 2018
URL https://recon-malta-2018.netlify.com/
 
Description Introduction to outbreak response analytics using R with WHO Afro (Thibaut Jombart) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Third sector organisations
Results and Impact Workshop in Cotonou, Benin
Year(s) Of Engagement Activity 2018
 
Description Invited talk at STD Prevention Conference (Erik Volz) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact The purpose of the talk was to describe the molecular epidemiology of HIV
Year(s) Of Engagement Activity 2018
URL https://www.cdc.gov/stdconference/default.htm
 
Description It all adds up: Maths conference for girls (Christl Donnelly) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Three day conference in maths for girls (typically only accommodating state schools) with the aim of inspiring girls to continue maths, and hearing about and engaging in all things maths alongside other girls.
Year(s) Of Engagement Activity 2017,2018,2019
URL https://www.maths.ox.ac.uk/study-here/undergraduate-study/outreach/it-all-adds
 
Description Lancet Countdown - European Launch event 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Hosted presenter + panel discussion for 2018 Lancet Countdown report on Climate Change and Health, held at Health and Environment Alliance in Brussels. Launch event attended by politicians (e.g., DG Sante), media, public, policymakers.
Year(s) Of Engagement Activity 2018
URL http://www.lancetcountdown.org/media/1420/2018-lancet-countdown-policy-brief-eu.pdf
 
Description London Centre NTD Research Anniversary Event 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Other audiences
Results and Impact Annual Anniversary Research Symposium with key note speakers, research presentations and networking opportunities.
Year(s) Of Engagement Activity 2018,2019
URL https://www.londonntd.org/news/beyond-2020-presentation-highlights
 
Description Oxford - Mathematical Institute (09/01/2019) 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Schools
Results and Impact Presentation on the use of statistics in understanding the spread and control of infectious diseases: state funded, girls-only school audience.
Year(s) Of Engagement Activity 2019
 
Description Presentations and guidance to the ACTA Cryptococcal meningitis trial group 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Study participants or study members
Results and Impact Updating the ACTA African clinical trials group on data produced by our MRC research
Year(s) Of Engagement Activity 2017
 
Description Public Lecture, Emerging Fungal Infections, Sydney 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Regional
Primary Audience Public/other audiences
Results and Impact Public lecture, Fungal emerging disease, Sydney
Year(s) Of Engagement Activity 2018
 
Description Publication of research paper adapted for children in Science Journal for Kids 
Form Of Engagement Activity A magazine, newsletter or online publication
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Schools
Results and Impact Adapted version of research paper published in Journals for Kids. JfK is an American company that re-writes scientific papers into accessible reading for children and young adults. The purpose is to make scientific literature accessible to children and young adults.
Year(s) Of Engagement Activity 2018
URL https://www.sciencejournalforkids.org/search-articles/how-deadly-is-ebola
 
Description RDTs-ZMOHCC 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Professional Practitioners
Results and Impact Presentation of interim results showing levels and possible causes of errors in HIV test results obtained in national programmes in Zimbabwe to senior staff in the Zimbabwe Ministry of Health and Child Care. The results also showed high levels of HIV-negative laboratory tests for people living with HIV infection who were already stable on antiretroviral treatment. Requested to conduct further laboratory tests to establish the true HIV infection status of the study subjects.
Year(s) Of Engagement Activity 2018
 
Description RECON Gathering (Thibaut Jombart) 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Professional Practitioners
Results and Impact Challenges and Opportunities in Outbreak Response Analytics; this event held in London includes a one-day symposium followed by a day of workshops with 2 parallel sessions: i) a discussion of analytic resources for field epidemiology training, and ii) a community-driven hackathon.
Year(s) Of Engagement Activity 2018
URL https://recon-gathering-march2018.netlify.com/
 
Description Royal Society Diversity Conference (Christl Donnelly) 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach National
Primary Audience Other audiences
Results and Impact Chaired Round Table discussion on achieving diverse leadership in a research environment
Year(s) Of Engagement Activity 2018
URL https://royalsociety.org/science-events-and-lectures/2018/11/annual-diversity-conference-2018/
 
Description Societal engagement award for combatting HIV stigma 
Form Of Engagement Activity Participation in an activity, workshop or similar
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Public/other audiences
Results and Impact Combatting HIV stigma
Year(s) Of Engagement Activity 2018
 
Description Talk at Northampton High School: University and career paths, Caroline Chisholm school 
Form Of Engagement Activity A talk or presentation
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Talk
Year(s) Of Engagement Activity 2018
 
Description The Economics of HIV 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact "Understanding the Economics of Microbial Threats", Working Group, lecture and expert member, National Academies of Sciences, Engineering, and Medicine, Washington (D.C.), June
Year(s) Of Engagement Activity 2018
URL http://www.nationalacademies.org/hmd/Activities/PublicHealth/microbialthreats/2018-JUN-12/Videos/S1/...
 
Description WHO - Global Malaria Programme 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Policymakers/politicians
Results and Impact Gave evidence for a policy recommendation for a new type of bed net for malaria control.
Year(s) Of Engagement Activity 2018
 
Description WHO - Global Malaria Programme - Insecticide resistance management 
Form Of Engagement Activity A broadcast e.g. TV/radio/film/podcast (other than news/press)
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Third sector organisations
Results and Impact A webminar where we discussed changes in the level of insecticide resistant mosquitoes in Africa
Year(s) Of Engagement Activity 2018
 
Description WILDLIFE DISEASES ON THE INCREASE: A MAJOR THREAT FOR EUROPE'S BIODIVERSITY 
Form Of Engagement Activity A formal working group, expert panel or dialogue
Part Of Official Scheme? No
Geographic Reach International
Primary Audience Media (as a channel to the public)
Results and Impact IUCN policy brief to the European Parliament

Change to incoming EU 'Animal Health' Law
Year(s) Of Engagement Activity 2013
URL http://www.biodiversa.org/552
 
Description work experience students for one week practicals in the lab + one lady who did a three month placement after her A levels 
Form Of Engagement Activity Participation in an open day or visit at my research institution
Part Of Official Scheme? No
Geographic Reach Local
Primary Audience Schools
Results and Impact Three groups of work experience students for one week practicals in the lab and one lady who did a three month placement with us after her A levels.
Year(s) Of Engagement Activity 2018