Cognitive Modelling of Phantom Limb Pain: investigating the plausibility of a predictive coding framework to explain phantom limb pain.

Lead Research Organisation: University of Oxford
Department Name: Clinical Neurosciences


Phantom limb pain (PLP) is a debilitating condition, occurring after limb amputation.
Traditionally, PLP is thought to be driven by maladaptive plasticity in the sensorimotor cortex1. However, treatment associated with such neural hypotheses (e.g. mirror-box therapy) report limited success.
Study 1. Is sensitivity to prediction error related to PLP?
Study 2. Is sensitivity to prediction error arising from phantom movement associated with PLP?
Study 3. Is prediction error, associated with PLP, generated by an aberrant internal model of phantom motor control?


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