Multi-scale models for the prediction of bone remodelling due to musculoskeletal interventions

Lead Research Organisation: University of Sheffield
Department Name: Oncology and Metabolism

Abstract

The hypothesis of this project is that multi-scale computational models can accurately predict bone changes over time due to osteoporosis and related interventions. The project aims at developing the first multi-scale biomechanical model for the prediction of bone changes over time in the mouse tibia due to external biomechanical and biochemical stimuli, and at validating its outcomes versus state-of-the-art longitudinal micro-computed tomography (microCT) measurements of bone changes

Publications

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Studentship Projects

Project Reference Relationship Related To Start End Student Name
EP/T517835/1 01/10/2020 30/09/2025
2458972 Studentship EP/T517835/1 26/10/2020 13/04/2024 Saira O'Reilly