Photo-Electro: Transforming Chemical Synthesis, Discovery and Manufacture
Lead Research Organisation:
University of Nottingham
Abstract
Our vision is to use continuous photochemistry and electrochemistry to transform how fine chemicals, agrochemicals and pharmaceuticals are manufactured in the UK. We aim to minimize the amount of chemicals, solvents and processing steps needed to construct complex molecules. We will achieve this by exploiting light and/or electricity to promote more specific chemical transformations and cleaner processes. By linking continuous photochemistry and electro-chemistry with thermal flow chemistry and environmentally acceptable solvents, we will create a toolkit with the power to transform all aspects of chemical synthesis from initial discovery through to chemical manufacturing of high-value molecules.
The objective is to increase efficiency in terms of both atoms and energy, resulting in lower cost, low waste, low solvent footprints and shorter manufacturing routes. Historically photo- and electro-chemistry have been under-utilised in academia and industry because they are perceived to be complicated to use, difficult to scale up and engineer into viable processes despite their obvious environmental, energy and cost benefits. We will combine the strategies and the skills needed to overcome these barriers and will open up new areas of science, and deliver a step-change (i) providing routes to novel molecular architectures, hard to reach or even inaccessible by conventional methodologies, (ii) eliminating many toxic reagents by rendering them unnecessary, (iii) minimizing solvent usage, (iv) promoting new methodologies for synthetic route planning. Our proposal is supported by 21 industrial partners covering a broad range of sectors of the chemistry-using industries who are offering £1.23M in-kind support.
Therefore, we will study a broad range of reactions to provide a clear understanding of the most effective areas for applying our techniques; we will evaluate strategies for altering the underlying photophysics and kinetics so as to accelerate the efficiency of promising reactions; we will transform our current designs of photochemical and electrochemical reactors, with a combination of engineering, modelling and new fabrication techniques to maximize their efficiency and to provide clear opportunities for scale-up; we will exploit on-line analytics to accelerate the optimisation of continuous photochemical and electrochemical reactions; we will design and build a new generation of reactors for new applications; we will identify the most effective strategies for linking our reactors into integrated multi-step continuous processes with minimized waste; we will demonstrate this integration on at least one synthesis of a representative pharmaceutical target molecule on a larger scale; we will apply a robust series of sustainability metrics to benchmark our approaches against current manufacturing.
The objective is to increase efficiency in terms of both atoms and energy, resulting in lower cost, low waste, low solvent footprints and shorter manufacturing routes. Historically photo- and electro-chemistry have been under-utilised in academia and industry because they are perceived to be complicated to use, difficult to scale up and engineer into viable processes despite their obvious environmental, energy and cost benefits. We will combine the strategies and the skills needed to overcome these barriers and will open up new areas of science, and deliver a step-change (i) providing routes to novel molecular architectures, hard to reach or even inaccessible by conventional methodologies, (ii) eliminating many toxic reagents by rendering them unnecessary, (iii) minimizing solvent usage, (iv) promoting new methodologies for synthetic route planning. Our proposal is supported by 21 industrial partners covering a broad range of sectors of the chemistry-using industries who are offering £1.23M in-kind support.
Therefore, we will study a broad range of reactions to provide a clear understanding of the most effective areas for applying our techniques; we will evaluate strategies for altering the underlying photophysics and kinetics so as to accelerate the efficiency of promising reactions; we will transform our current designs of photochemical and electrochemical reactors, with a combination of engineering, modelling and new fabrication techniques to maximize their efficiency and to provide clear opportunities for scale-up; we will exploit on-line analytics to accelerate the optimisation of continuous photochemical and electrochemical reactions; we will design and build a new generation of reactors for new applications; we will identify the most effective strategies for linking our reactors into integrated multi-step continuous processes with minimized waste; we will demonstrate this integration on at least one synthesis of a representative pharmaceutical target molecule on a larger scale; we will apply a robust series of sustainability metrics to benchmark our approaches against current manufacturing.
Planned Impact
Our Programme, Photo-Electro, will have substantial impact on chemists in academia and industry because we will demonstrate the value of continuous photo-, electro- and thermochemistry to make complex molecules. Making such molecules is a key activity in a wide range of UK chemistry-using industries. These include pharmaceutical and agrochemical manufacture as well as companies making speciality chemicals for fragrances and many other end products. Such industries are under constant regulatory and financial pressure to develop processes that are environmentally and economically more efficient than current methodologies. Therefore, our approach of replacing toxic and/or wasteful stoichiometric reagents by light, electricity and heat, has great attractions as demonstrated by the letters of support from our 21 industrial partners.
What makes our programme different is that we are using light, electricity and heat together to deliver integrated processes to carry out multi-step assembly of complex molecules. At the same time, we are designing and building new continuous reactors which, by the end of the Programme, will be available to non-specialist chemists in industry and academia. The designs will be informed by computer fluid modelling and chemical engineering so that we maximise the efficiencies of both mass and heat transfer. Our reactors are intended to be both reliable and scalable so as to simplify their eventual introduction into commercial chemical production. We have a robust strategy for impact. Our industrial partners will form a stakeholders' forum to engage with our research right from the start. The Forum is intended to be inclusive and new members will be warmly welcomed at any stage of our programme. Photo-Electro is particularly timely as it will deliver new methodologies which can increase the competivity of UK chemical manufacturing. And, in this period of post-referendum uncertainty, increasing that competivity must be a national priority.
What makes our programme different is that we are using light, electricity and heat together to deliver integrated processes to carry out multi-step assembly of complex molecules. At the same time, we are designing and building new continuous reactors which, by the end of the Programme, will be available to non-specialist chemists in industry and academia. The designs will be informed by computer fluid modelling and chemical engineering so that we maximise the efficiencies of both mass and heat transfer. Our reactors are intended to be both reliable and scalable so as to simplify their eventual introduction into commercial chemical production. We have a robust strategy for impact. Our industrial partners will form a stakeholders' forum to engage with our research right from the start. The Forum is intended to be inclusive and new members will be warmly welcomed at any stage of our programme. Photo-Electro is particularly timely as it will deliver new methodologies which can increase the competivity of UK chemical manufacturing. And, in this period of post-referendum uncertainty, increasing that competivity must be a national priority.
Organisations
- University of Nottingham (Lead Research Organisation)
- Centre for Process Innovation (CPI) (Collaboration)
- Unilever (Netherlands) (Collaboration)
- Beta Technology Ltd (Collaboration)
- Hel Group (Collaboration)
- Enlumo Ltd (Collaboration, Project Partner)
- Britest (Collaboration)
- Johnson Matthey (United Kingdom) (Collaboration)
- GlaxoSmithKline (GSK) (Collaboration)
- Mettler-Toledo Auto Chem (Collaboration)
- Arcinova (Collaboration)
- Ansys, Inc (Collaboration)
- Siemens (United Kingdom) (Collaboration)
- Innovate UK (Collaboration, Project Partner)
- Huvepharma (Bulgaria) (Collaboration)
- Thomas Swan and Co Ltd (Collaboration)
- MERCK (Collaboration)
- AstraZeneca (United Kingdom) (Collaboration, Project Partner)
- Uniqsis Ltd (Collaboration, Project Partner)
- Syngenta International AG (Collaboration)
- Givaudan (Collaboration)
- Novartis (Collaboration)
- Eli Lilly & Company Ltd (Collaboration)
- Cambridge Reactor Design (Collaboration)
- Sanofi (United Kingdom) (Collaboration)
- Asynt Ltd (Collaboration)
- Ansys (United States) (Project Partner)
- HEL Group (United Kingdom) (Project Partner)
- Arc Trinova Ltd (Arcinova) (Project Partner)
- GlaxoSmithKline (United Kingdom) (Project Partner)
- Cambridge Reactor Design (United Kingdom) (Project Partner)
- Novartis (Switzerland) (Project Partner)
- Centre for Process Innovation (Project Partner)
- Merck (United Kingdom) (Project Partner)
- Sanofi (Germany) (Project Partner)
- Asynt (Project Partner)
- Unilever (United Kingdom) (Project Partner)
- Thomas Swan (United Kingdom) (Project Partner)
- Eli Lilly (United States) (Project Partner)
- Britest Limited (Project Partner)
- Givaudan (Switzerland) (Project Partner)
- Syngenta (United Kingdom) (Project Partner)
Publications
Al-Hadedi AAM
(2022)
A flow electrochemistry-enabled synthesis of 2-substituted N-(methyl-d)piperidines.
in Journal of labelled compounds & radiopharmaceuticals
Almalki F
(2020)
Total synthesis of polymorphatin A, a macrocyclic bisbibenzyl with boat configured arenes
in Tetrahedron
Bennett RM
(2021)
A new mode of cyclobutenedione ring opening for the synthesis of 2-oxobut-3-enamides and tetrasubstituted furans.
in Chemical communications (Cambridge, England)
Clark C
(2018)
UV PhotoVap: Demonstrating How a Simple and Versatile Reactor Based on a Conventional Rotary Evaporator Can Be Used for UV Photochemistry
in Organic Process Research & Development
Clarke C
(2022)
Halometallate ionic liquids: thermal properties, decomposition pathways, and life cycle considerations
in Green Chemistry
Clarke C
(2021)
Linking the Thermal and Electronic Properties of Functional Dicationic Salts with Their Molecular Structures
in ACS Sustainable Chemistry & Engineering
Clarke C
(2020)
Thermally-Stable Imidazolium Dicationic Ionic Liquids with Pyridine Functional Groups
in ACS Sustainable Chemistry & Engineering
Collin DE
(2020)
Cubane Electrochemistry: Direct Conversion of Cubane Carboxylic Acids to Alkoxy Cubanes Using the Hofer-Moest Reaction under Flow Conditions.
in Chemistry (Weinheim an der Bergstrasse, Germany)
Cox B
(2019)
Escaping from Flatland: [2 + 2] Photocycloaddition; Conformationally Constrained sp3-rich Scaffolds for Lead Generation.
in ACS medicinal chemistry letters
| Description | Photo-Electro seeks to transform the manufacturing of fine chemicals, pharmaceuticals and agrochemicals by using photochemistry and electrochemistry. We aim to reduce the use of solvents, chemicals, and processing steps needed to synthesize complex molecular structures. The objective is to increase efficiency in terms of both atoms and energy, resulting in lower cost, low waste, low solvent footprints and shorter manufacturing routes. Historically photo- and electro-chemistry have been under-utilised in academia and industry because they are perceived to be complicated to use, difficult to scale up and engineer into viable processes despite their obvious environmental, energy and cost benefits. We will combine the strategies and the skills needed to overcome these barriers and will open up new areas of science, and deliver a step-change (i) providing routes to novel molecular architectures, hard to reach or even inaccessible by conventional methodologies, (ii) eliminating many toxic reagents by rendering them unnecessary, (iii) minimizing solvent usage, (iv) promoting new methodologies for synthetic route planning. |
| Description | All Party Group on Malaria & Neglected Tropical Diseases, Houses of Parliament |
| Geographic Reach | National |
| Policy Influence Type | Contribution to a national consultation/review |
| Description | Science & Engineering Network at the Department of Business Enterprise & Industrial Strategy |
| Geographic Reach | National |
| Policy Influence Type | Influenced training of practitioners or researchers |
| Description | Flow-inova: Innovation in manufacturing medicines |
| Amount | £1,439,929 (GBP) |
| Funding ID | 104202 |
| Organisation | Innovate UK |
| Sector | Public |
| Country | United Kingdom |
| Start | 03/2018 |
| End | 03/2021 |
| Description | Manufacture of Anti-Malarial Compounds |
| Amount | $556,406 (USD) |
| Funding ID | OPP1191959 |
| Organisation | Bill and Melinda Gates Foundation |
| Sector | Charity/Non Profit |
| Country | United States |
| Start | 08/2018 |
| End | 01/2020 |
| Description | Project STORM - SusTainable OxychloRination developMent |
| Amount | £160,264 (GBP) |
| Funding ID | 80811 |
| Organisation | Innovate UK |
| Sector | Public |
| Country | United Kingdom |
| Start | 08/2020 |
| End | 09/2021 |
| Title | Dataset in support of the Southampton doctoral thesis 'Flow Photochemical Routes to Indoles and 8-membered Lactones, and their Application in Target Synthesis' |
| Description | This file includes NMR data for all compounds seen in the thesis experimental, collected using NMR machines in B29, University of Southampton (use ACDLabs to view). It also includes IR data, collected on IR machine in B30, University of Southampton (Use ACDLabs to view). Also included is HRMS data collected by the MS department, B30, University of Southampton. |
| Type Of Material | Database/Collection of data |
| Year Produced | 2023 |
| Provided To Others? | Yes |
| URL | https://eprints.soton.ac.uk/id/eprint/473340 |
| Description | PhotoElectro Stakeholders |
| Organisation | Ansys, Inc |
| Country | United States |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Arcinova |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | AstraZeneca |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Asynt Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Beta Technology Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Britest |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Cambridge Reactor Design |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Centre for Process Innovation (CPI) |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Eli Lilly & Company Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Enlumo Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Givaudan |
| Country | Switzerland |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | GlaxoSmithKline (GSK) |
| Country | Global |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Hel Group |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Huvepharma |
| Country | Bulgaria |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Johnson Matthey |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Knowledge Transfer Network |
| Country | United Kingdom |
| Sector | Charity/Non Profit |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Merck |
| Country | Germany |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Mettler-Toledo Auto Chem |
| Country | United States |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Novartis |
| Country | Global |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Sanofi |
| Country | Global |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Siemens Process Systems Engineering Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Syngenta International AG |
| Country | Switzerland |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Thomas Swan and Co Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Unilever |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | PhotoElectro Stakeholders |
| Organisation | Uniqsis Ltd |
| Country | United Kingdom |
| Sector | Private |
| PI Contribution | PhotoElectro researchers presented pre-competitive research of interest to stakeholders at the annual Stakeholders Forum. Huvepharma, Mettler-Toledo AutoChem Inc. and Photodiversity joined as PhotoElectro Stakeholders in 2018. |
| Collaborator Contribution | PhotoElectro Stakeholders attended and gave advice to PhotoElectro researchers on current research being conducted at the annual Stakeholders Forum. |
| Impact | Five publications have come out of PhotoElectro: DOI: 10.1039/C7RE00193B, DOI 10.1016/j.tet.2017.11.048, DOI: 10.1021/acs.chemrev.7b00360, DOI: 10.1021/acs.oprd.7b00153, DOI: 10.1039/C6GC02888H |
| Start Year | 2017 |
| Description | A talk or presentation - Research Lectures: AL |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Dr Alastair Lennox gave an invited lecture at the 239th Electrochemical Society conference "Advances in Organic and Biological Electrochemistry: In memory of Dennis Peters" symposium, which was held online between May 30th and June 3rd 2021. |
| Year(s) Of Engagement Activity | 2021 |
| Description | A talk or presentation - Research Lectures: WS |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Wei Sun presented "Sequencing Thermal and Photochemical Ring Expansion Reactions in Flow for the Synthesis of 8-Membered Nitrogen Heterocycles from Cyclobutenones" at the Royal Society of Chemistry Heterocyclic & Synthesis Group Postdoctoral Symposium. |
| Year(s) Of Engagement Activity | 2021 |
| Description | Bristol Electrosynthesis Meeting 2022 AL |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Electrosynthesis meeting with 2 plenary speakers with PhD talks and poster session |
| Year(s) Of Engagement Activity | 2022 |
| Description | Conference Presentation: DL |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Professional Practitioners |
| Results and Impact | Dr. Darren Lee presented "Towards Greener Photochemistry" at the 2nd Green and Sustainable Chemistry conference in Berlin, Germany. The research lecture was aimed at increasing interest and furthering research ideas within the field. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Conference Talk Towards Greener Photo Chemistry |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Invited Zoom Presentation |
| Year(s) Of Engagement Activity | 2022 |
| Description | Discussion to take place in Edinburgh in July 2023 RB |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | • Electrosynthesis Faraday Discussion, 12 - 14 July 2023, Edinburgh, UK. Talk (Invited speaker, Title tbc) |
| Year(s) Of Engagement Activity | 2023 |
| Description | Lecture |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Lecture at Smart Textiles for Regional Industry Meeting on the development of new inks for eTextiles applications |
| Year(s) Of Engagement Activity | 2023 |
| Description | PhotoElectro Stakeholders Forum |
| Form Of Engagement Activity | A formal working group, expert panel or dialogue |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | PhotoElectro meets annually with all Stakeholders at a Stakeholders Forum. This event is meant to harbour two way communication between PhotoElecro researchers and industrial partners. Research is discussed leading to new ideas and collaborations. |
| Year(s) Of Engagement Activity | 2017,2018 |
| Description | PhotoElectro Twitter |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Public/other audiences |
| Results and Impact | PhotoElectro created a Twitter Account in November 2019 to disseminate our outreach efforts and research further. |
| Year(s) Of Engagement Activity | 2019,2020,2021 |
| URL | https://twitter.com/PhotoElectroSci |
| Description | PhotoElectro Website |
| Form Of Engagement Activity | Engagement focused website, blog or social media channel |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Industry/Business |
| Results and Impact | PhotoElectro has developed a public facing website aimed at disseminating the research activity occurring within the programme. the website highlights the research impact, industrial partnerships, publications, and accomplishments of PhotoElectro. It is consistently updated with the latest news to provide up to date information. |
| Year(s) Of Engagement Activity | 2017,2018,2019,2020,2021 |
| URL | https://www.nottingham.ac.uk/research/groups/photoelectro/photo-electro.aspx |
| Description | Plenary Lecture: "A Flow Approach to Organic Electrosynthesis" RB |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Plenary Lecture: Indo-UK Symposium for Enabling Chemical Technologies for Sustainability. Queen Mary University of London 19th and 20th January 2023. Title "A Flow Approach to Organic Electrosynthesis" |
| Year(s) Of Engagement Activity | 2023 |
| Description | Research Lecture: KEJ |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Industry/Business |
| Results and Impact | Katie gave lectures on her research at the Eli Lilly 50 year Celebratory Symposium in Erl Wood in 2017. |
| Year(s) Of Engagement Activity | 2017 |
| Description | Research Lectures: DCH |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Dial a Molecule, Channel Research Day, Synflux Symposium on Synthesis in Flow |
| Year(s) Of Engagement Activity | 2018,2019 |
| Description | Research Lectures: KBM |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Industry/Business |
| Results and Impact | Kevin Booker-Milburn gave lectures to industries including Charles Ricer (Cambridge, UK), Evotec (Abingdon, UK), and Kings College (London, UK) as part of the PhotoElectro Team. |
| Year(s) Of Engagement Activity | 2017,2018,2019 |
| Description | Research Lectures: MP |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Prof Sir Martyn Poliakoff has lectured "Towards Greener Chemistry" and "Continuous Green Chemistry" on local, national, and international levels. Since the start of PhotoElectro, Prof Poliakoff has given over 30 outreach lectures at venues including but not limited to: The Stokes Society, Imperial College, ENEQUI XXI (San Paulo, Brazil), industries including Givauden, Novartis and EPFL (Switzerland), and the Ashbourne Festival to name a few. Additionally, he was invited to give the James Walker Memorial Lecture and the University of Edinburgh. Each lecture was aimed at disseminating the importance and progress within green chemistry. Interest within the subject was increased after the lectures. In 2020 Sir Martyn gave an on-line talk "The elements of Chemistry" to ca 200 sixth-formers via the West Midlands Chemistry teachers' Forum in Birmingham in November. He also gave a video lecture "Frontiers of Green & Sustainable Chemistry" via University of Nottingham Nignbo Campus in November. In 2021 Sir Martyn presented the following online talks co-authored with Prof Michael George "Towards Greener Photochemistry" Plenary, GDCh-JungChemiker Forum (April);"Towards Greener Photochemistry" Lecture to Masters Students at the University of Alcalá, Spain (May)"Towards Greener Photochemistry (in Russian)" VI All-Russian Forum "Science of the Future - Science of the Young" (November, video of this session had been watched more than seventy thousand times within 12 hours)"Supercriticality :from Blue Fluid to Green Chemistry" St Andrews Interdisciplinary Science Conference, February 2022 |
| Year(s) Of Engagement Activity | 2017,2018,2019,2020,2021,2022 |
| Description | Research Lectures: MWG |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Prof Michael George presented "Photochemistry, Spectroscopy and Supercritical Fluids: From Organometallic Alkane Complexes and C-H Activation to the Synthesis of Anti-Malarial Drugs" at the University of Otago, New Zealand. This lecture increased interest in photo-chemistry and exposed undergraduate and post-graduate researchers to the field. He also presented "Photochemistry, Spectroscopy, and Supercritical Fluids: From organometallic Alkane Complexes and C-H Activation to the synthesis of anti-malarial drugs" at ESPCI, Paris and the University of Sheffield. "Approaches to Scaling-up linked Continuous Flow Photo-,Electro-and Thermal-chemistry at Scale-New Reactors and New Approaches-From Picoseconds to Tonnes" Virtual Sustainability Workshop, University Jaume, Castellon, Spain. |
| Year(s) Of Engagement Activity | 2017,2018,2019,2020 |
| Description | Research Lectures: PL |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | 19 lectures including UNIDO Green Chemistry Awareness Day, IUPAC Summer School on Green Chemistry, the University of York, and Queen's University of Belfast |
| Year(s) Of Engagement Activity | 2017,2018,2019 |
| Description | Research Lectures: RCDB |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Prof Richard Brown presented "Preparative Electrosynthesis Using Undivided, Extended Channel Length, Flow Reactors", "Practical Organic Electrosynthesis in Laboratory Flow Electrolysis Cells with Extended Channels: Milligrammes/Hour" and "Approaches to Preparative Electrosynthesis" at conferences and seminars across the UK. The lectures were aimed at increasing knowledge of and interest in electrochemistry. Additionally in 2018, that lectures were given to GSK (Stevenage, UK), Charles River (Chesterford Research Park, UK), and the University of Greenwich. In 2021 Prof Richard Brown presented 'Organic Electrosynthesis in Flow Reactors with Extended Channels' to the iPRD (Institute of Process Research and Development) in April at the Industrial Club at the University of Leeds via Microsoft Teams. In Oct 21 Richard Brown spoke in the Flow Chemistry session at the Lorentz Center Workshop on Electrifying Chemistry: from fundamentals to industrial application held in Leiden, the Netherlands. |
| Year(s) Of Engagement Activity | 2017,2018,2019,2021 |
| Description | Research Seminar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Postgraduate students |
| Results and Impact | Seminar at University of Sussex - Using Heat, Light and Electricity to Achieve Useful, Atom-Efficient Reactions under Flow |
| Year(s) Of Engagement Activity | 2023 |
| Description | Research Seminar |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Other audiences |
| Results and Impact | Electrosynthesis in flow: Substituting chemical reagents with electrons |
| Year(s) Of Engagement Activity | 2022 |
| Description | Research Seminar Oxidative and Reductive electrosynthesis in extended channel flow cells" RB |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | Oxidative and Reductive electrosynthesis in extended channel flow cells" |
| Year(s) Of Engagement Activity | 2022 |
| Description | Royal Society Summer Science Exhibition |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | PhotoElectro exhibited at the Royals Society's Summer Science Exhibition, a week-long outreach event aimed at communicating state-of-the-art research to the public. The team presented an exhibit entitled 'Green Light for Chemistry' which highlighted the need for change within chemical manufacturing and how PhotoElectro's research is trying to make chemical manufacture more sustainable through the use of reactors designed to use photo- and electro- flow chemistry. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://royalsociety.org/science-events-and-lectures/2019/summer-science-exhibition/ |
| Description | Royal Society of Chemistry and Royal Institution's 'For Your Inspiration: the elements of success' |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | National |
| Primary Audience | Public/other audiences |
| Results and Impact | PhotoElectro exhibited 'Green Light for Chemistry' which has hands on activities to communicate PhotoElectro's research. These activities included model reactors with colour changing light reactions. The event was aimed at 12+ year olds to increase their knowledge on careers in chemistry. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.rigb.org/whats-on/events-2019/november/family-for-your-inspiration-the-elements-of-succ |
| Description | Solvay Workshop - Organic electrosynthesis in flow reactors RB |
| Form Of Engagement Activity | A talk or presentation |
| Part Of Official Scheme? | No |
| Geographic Reach | International |
| Primary Audience | Postgraduate students |
| Results and Impact | • Solvay Workshop "New ways to do chemistry Emerging technologies for synthetic methodology" Brussels, 24 - 26 April 2023 Talk: "Organic electrosynthesis in flow reactors |
| Year(s) Of Engagement Activity | 2023 |
| Description | Training Session for Industrial Scientists |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Local |
| Primary Audience | Industry/Business |
| Results and Impact | Richard Brown held training sessions for Industrial Scientists on flow organic electrosynthesis, and electrochemical techniques such as cyclic voltammetry. An introduction to some of the underpinning theory, and practical demonstrations were provided, and these were very well received. |
| Year(s) Of Engagement Activity | 2018 |
| Description | University of Nottingham's 'Wonder' Event |
| Form Of Engagement Activity | Participation in an activity, workshop or similar |
| Part Of Official Scheme? | No |
| Geographic Reach | Regional |
| Primary Audience | Public/other audiences |
| Results and Impact | PhotoElectro exhibited at the University of Nottingham's 'Wonder' event which is an interactive community event celebrating research at the university. This is the University of Nottingham's largest outreach event hosting around 5K visitors. The feedback report from DH Insight revealed that the chemistry activities were the most popular activities. |
| Year(s) Of Engagement Activity | 2019 |
| URL | https://www.nottingham.ac.uk/wonder/documents/wonder-programme.pdf |