The Avon Longitudinal Study of Parents and Children (ALSPAC): A multi-generation, longitudinal resource

Lead Research Organisation: University of Bristol

Abstract

Between April 1991 and December 1992 we enrolled >14000 pregnant women in ALSPAC resulting in 14062 live births. Mothers, fathers, children and now children of the children from this recruitment have been followed up at multiple timepoints and a wide variety of samples, exposure and outcome measures collected.
Our mission is to ensure ALSPAC remains the premier multi-generational birth cohort offering unrivalled access to data and samples. We will look after the existing samples and data, improve visibility and access to the existing resource, maximise the connection of administrative data and continue collecting new data and samples.
Maintaining such a valuable UK resource will enable research uniquely equipped to follow changes in health and well-being across the lifespan, what affects this, how certain factors work across generations, and how changes in society affect the health and well-being of families going through similar events 30 years apart."

Technical Summary

ALSPAC is a multi-generation (G0/G1/G2), prospective cohort based in the UK [1-4] (supplementary information, Figure 1). This proposal seeks support to:
- Maintain the existing samples and data resources.
- Enhance visibility and access to data and samples.
- Maximise linkage opportunities through broad and innovative use of administrative records.
- Expand the resource by maximising recruitment and retention, and collecting new data and
samples on original parents (G0), index participants (G1) and the next generation (G2).
Work will be delivered via an efficient operational and governance infrastructure. We will deploy a combination of face-to-face assessment, biosample collection and analysis, remote data collection and administrative record linkage where the value of this activity is substantially enhanced by existing resources. All proposed work has been designed according to the overarching principles of (i) scientific utility and (ii) engagement/recruitment/retention. Study activities draw on experience from previous ALSPAC activity and consultation with participants and academics through bespoke workshops. Scientific focus reflects ALSPAC strengths and our target science areas, namely: The antecedents of cardiometabolic/cognitive/mental health, cross-generation contributions to health and era specific contributions to health, well-being and society."

Organisations

Publications

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Abdulkadir M (2022) Eating disorder symptoms and their associations with anthropometric and psychiatric polygenic scores. in European eating disorders review : the journal of the Eating Disorders Association

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Abeysekera KWM (2020) Prevalence of steatosis and fibrosis in young adults in the UK: a population-based study. in The lancet. Gastroenterology & hepatology

 
Title Data visualisation images on display at We The Curious's Project 'What If' exhibition 2021 
Description Researchers using ALSPAC data provided imagery for the Open Science lab at We The Curious, Bristol's science centre. Tom Gaunt, Matthew Lee & others provided images to exhibit and create conversations about data collection in ALSPAC. 
Type Of Art Artwork 
Year Produced 2021 
Impact Created opportunities for discussion about population health science in a public space. 
URL https://www.youtube.com/watch?v=TdiOA7Aj3dE
 
Title Short film on health inequality by Nic Timpson 
Description Short film with a talking head by Prof Nic Timpson discussing health inequality to accompany an exhibit 'Bristol Health Map' at We The Curious science centre in Bristol 
Type Of Art Artistic/Creative Exhibition 
Year Produced 2021 
Impact Created an opportunity for discussion around the exhibit Bristol Health Map - showing disparities in health and life expectancies around different wards in Bristol 
URL https://drive.google.com/file/d/1_lv_RUhos9BxJ3H8qT-gfbycFZdAIH-c/view
 
Description A longitudinal study of gambling in late adolescence and early adulthood: Follow-up assessment at 24 years
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact This report describes a longitudinal study of young peoples' gambling between 17 and 24 years, using a contemporary UK cohort, the Avon Longitudinal Study of Parents and Children (ALSPAC). The aims of the ALSPAC Gambling Study were to describe gambling behaviour in youth aged 17-24 years, investigate the antecedents of regular and problem gambling, and explore the associations with other addictive behaviours and mental health.
URL https://www.begambleaware.org/media/2058/alspac-gambling-study_-report-for-gamble-aware_-july-2019.p...
 
Description ALSPAC Summary for SAGE re: COVID and children/young people
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
URL https://hdruk.app.box.com/s/c4p2w3n673js8run56qcbnhtyvjdwyys
 
Description COVID-19 Health Data Research 04 August 2020 - Weekly update for SAGE & UKRI/DHS
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
URL https://www.hdruk.ac.uk/wp-content/uploads/2020/08/200804-Health-Data-Research-UK-COVID-19-fortnight...
 
Description COVID-19 Health Data Research 18 August 2020 - Weekly update for SAGE & UKRI/DHSC
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
URL https://www.hdruk.ac.uk/wp-content/uploads/2020/08/200818-Health-Data-Research-UK-COVID-19-fortnight...
 
Description COVID-19 mental health and wellbeing surveillance report (series)
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL https://www.gov.uk/government/publications/covid-19-mental-health-and-wellbeing-surveillance-report/...
 
Description COVID-19 mental health and wellbeing surveillance: report
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
URL https://www.gov.uk/government/publications/covid-19-mental-health-and-wellbeing-surveillance-report
 
Description Cohorts knowledge panel - CIHR & Genomes Canada
Geographic Reach North America 
Policy Influence Type Membership of a guideline committee
 
Description Department for Education on grandparental care during COVID-19 pandemic and mitigation.
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL https://www.gov.uk/government/publications/quick-findings-on-age-distributions-of-grandparents-and-p...
 
Description Eating disorder symptoms and self-harm are linked to higher levels of depression and anxiety during the COVID-19 pandemic
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
URL https://www.bristol.ac.uk/media-library/sites/policybristol/briefings-and-reports-pdfs/2021/PolicyBr...
 
Description HDRUK - Lessons from COVID-19: How can we put the UK at the forefront of health data science?
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
URL https://www.hdruk.ac.uk/wp-content/uploads/2020/07/Lessons-from-COVID-19-for-UK-Health-Data-Science....
 
Description HDRUK - regular updates for SAGE, National Core Studies & UKRI/DHSC (ALSPAC have contribute to 7 of these)
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
URL https://www.hdruk.ac.uk/wp-content/uploads/2021/02/2021-02-23-Health-Data-Research-UK-SAGE-report.pd...
 
Description Health Data Research UK Infrastructure Advisory Group
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
URL https://www.hdruk.ac.uk/about-us/who-we-are/our-advisory-groups/
 
Description Impact of voluntary risk-mitigation behaviour on the magnitude of a COVID-19 Omicron variant wave in England, 11 January 2022
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
URL http://www.gov.uk/government/publications/university-of-bristol-impact-of-voluntary-risk-mitigation-...
 
Description Internet use and suicide
Geographic Reach Multiple continents/international 
Policy Influence Type Gave evidence to a government review
Impact Work has highlighted the importance of internet use for understanding the architecture of suicidal behaviour. It has been specifically supported by a Department of Health Policy Research Programme and an ESRC Impact Accelerator Account and has already fed into the All Party Parliamentary Group (APPG) on suicide, the APPG on Social Media and Young People's Mental Health, a report by the House of Commons Health Select Committee on Suicide Prevention https://publications.parliament.uk/pa/cm201617/cmselect/cmhealth/1087/1087.pdf, a Royal College of Psychiatrist Patient Safety report and reviews of industry practice (e.g. advising YouTube).
 
Description Maternal depression increases generation on generation.
Geographic Reach National 
Policy Influence Type Citation in other policy documents
Impact Pearson RM, et al. Prevalence of Prenatal Depression Symptoms Among 2 Generations of Pregnant Mothers. JAMA Network Open 2018, 1:e180725 KEY IMPACT - The findings have had global media attention including live tv and radio and the results have been commented on by the Royal College of Midwives and the Maternal Mental Health Alliance. The work is new and has not yet delivered measurable policy change, but highlights the need for increased support for young pregnant women in the current enviro-socio-economic climate. The research has already supported national campaigns to facilitate universal screening for depression (and anxiety) by midwives, for the prioritisation of pregnant women for free psychological therapies and for provision of specialist perinatal mental health community mental health teams across the UK.
 
Description Maternal iodine status in early pregnancy
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact Sarah Bath - University of Surrey- able to look back in time to maternal iodine status in early pregnancy so that we could explore the relationship with child cognition. Using ALSPAC was cost-effective as cognitive measures were available in the child, and samples were available from the mother which we could use for the measurement of maternal iodine status. ALSPAC, unlike many other biobanks had urine samples from very early in pregnancy - which was the time that we were interested in. Iodine and thyroid hormones are required from conception and during the first half of pregnancy the mother is the sole source of thyroid hormone and so adequate iodine is critical; we therefore wanted to measure iodine status as early as possible. ALSPAC also had dietary information, via the food frequency questionnaire completed in pregnancy, which we have been able to use in our follow-on project (EUthyroid - a Horizon 2020 project). Published our research paper in the Lancet in May 2013. Work cited as an example in Medical Research Council document "Outputs, outcomes and impact of MRC research: 2013/14 report". Publication of a fact sheet on iodine for the general public/health practitioners via the British Dietetic Association. Iodine now included in fact sheets for pregnant women by the Infant and Toddler Forum. Work cited in Dairy Council's new publication on iodine. Work cited in iodine review by the Scientific Advisory Committee on Nutrition (gov). Work cited by EFSA in document on Dietary Reference Value for iodine: European Food Safety Authority (2014) Scientific Opinion on Dietary Reference Values for iodine. EFSA Journal 12, 3660. Paper featured in NICE "Eyes on Evidence" February 2014. Further grant funding for follow-on project: European Commission Horizon 2020 EUthyroid: towards the elimination of iodine deficiency and preventable thyroid-related diseases in Europe. Grant agreement No 634453
 
Description Our Future Health Scientific Advisory Board
Geographic Reach National 
Policy Influence Type Membership of a guideline committee
URL https://ourfuturehealth.org.uk
 
Description PHE Mental health - Research and analysis 7. Age Spotlight Updated 18 November 2021
Geographic Reach National 
Policy Influence Type Implementation circular/rapid advice/letter to e.g. Ministry of Health
URL https://www.gov.uk/government/publications/covid-19-mental-health-and-wellbeing-surveillance-spotlig...
 
Description Participation in Department for Education's Childrenofthe2020s Cohort Technical Advisory Group
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
 
Description Quick findings on age distributions of grandparents and parents of primary school aged children - .gov (asset - Centre for Ageing and Demography)
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/8934...
 
Description Short Report on Long COVID - Office for National Statistics
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1007...
 
Description Where's the daddy? Fathers and father-figures in UK datasets - The Fatherhood Institute
Geographic Reach National 
Policy Influence Type Citation in systematic reviews
Impact Review aims - Firstly, for funders and providers of large-scale quantitative datasets, a documentation of questions and fieldwork practices which enable researchers to identify specific categories of fathers and collect data directly from fathers. Secondly, for researchers planning secondary analyses to study fathers, an assessment of whether different categories of fathers can be identified in the data. ALSPAC forms a key part of the evidence contained within this review.
 
Description (LONGITOOLS) - Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases
Amount € 11,997,449 (EUR)
Funding ID 874739 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 01/2020 
End 12/2024
 
Description A Recall by Genotype Study to investigate the role of common TRPA1 variants on acute pain perception
Amount £39,813 (GBP)
Organisation University Hospitals Bristol NHS Foundation Trust 
Department Above and Beyond Grants
Sector Charity/Non Profit
Country United Kingdom
Start 01/2019 
End 11/2021
 
Description A UK underpinning platform to study immunology and immunopathology of COVID-19:The UK Coronavirus Immunology Consortium
Amount £6,552,119 (GBP)
Funding ID MR/V028448/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 07/2020 
End 08/2021
 
Description Accumulative processes in health inequalities: the socioeconomic causes and consequences of mental and physical health comorbidity in adolescence
Amount £229,631 (GBP)
Funding ID ES/T013923/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 11/2020 
End 01/2023
 
Description Adult peak circulatory capacity in the Avon Longitudinal Study of Parents and Children (ALSPAC): mechanisms and exposures (ACME)
Amount £441,633 (GBP)
Funding ID SP/F/21/150020 
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2021 
End 06/2024
 
Description CLOSER (21/22 Extension)
Amount £55,000 (GBP)
Funding ID ES/K000357/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 03/2021 
End 03/2022
 
Description COVID-19 Longitudinal Health and Wellbeing - National Core Study (LWH-NCS)
Amount £9,862,000 (GBP)
Funding ID MC_PC_20030 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 09/2020 
End 03/2021
 
Description COVID-19 Questionnaire support
Amount £6,598 (GBP)
Organisation University of Bristol 
Sector Academic/University
Country United Kingdom
Start 03/2020 
End 07/2020
 
Description CRN West of England 19/20 ALSPAC Funding
Amount £27,994 (GBP)
Organisation UK Clinical Research Network (UKCRN) 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2019 
End 03/2020
 
Description CRN West of England 20/21 ALSPAC Funding
Amount £96,788 (GBP)
Organisation UK Clinical Research Network (UKCRN) 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2020 
End 03/2021
 
Description CRN West of England 21/22 ALSPAC Funding
Amount £96,541 (GBP)
Organisation UK Clinical Research Network (UKCRN) 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2021 
End 03/2022
 
Description Defining 'clinically actionable' genetic mechanisms in atopic eczema risk and resolution
Amount £2,258,810 (GBP)
Funding ID 220875/Z/20/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2020 
End 10/2025
 
Description Development and evaluation of a pathway from 'universal screening' to online intervention for children with anxiety problems
Amount £2,547,794 (GBP)
Funding ID RP-PG-0218-20010 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 06/2019 
End 06/2024
 
Description Emotional dysregulation, self-harm and eating disorders: a mechanistic investigation
Amount £251,713 (GBP)
Funding ID MR/S020292/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 08/2019 
End 09/2021
 
Description Extraordinary COVID-19 questionnaire
Amount £5,650 (GBP)
Organisation University of Bristol 
Department Elizabeth Blackwell Institute for Health Research
Sector Academic/University
Country United Kingdom
Start 03/2020 
End 03/2021
 
Description Investigating five large population-based cohort studies to understand for the precursors of multimorbidity risk.
Amount £74,159 (GBP)
Funding ID MR/V004905/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 07/2020 
End 02/2021
 
Description Lung Health @30. Understanding the origins of chronic lung disease and the impact of COVID-19
Amount £191,526 (GBP)
Organisation Southmead Hospital Charity 
Sector Public
Country United Kingdom
Start 09/2021 
End 09/2025
 
Description Molecular Genetic and Lifecourse Epidemiology
Amount £5,153,712 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 08/2021 
End 09/2025
 
Description Physical and mental health multimorbidity across the lifespan (LIfespaN multimorbidity research Collaborative (LINC)).
Amount £3,034,322 (GBP)
Funding ID MR/W014416/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 12/2021 
End 11/2025
 
Description Psychosocial mechanisms of chronic pain
Amount £3,824,159 (GBP)
Funding ID MR/W004151/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 06/2021 
End 06/2025
 
Description Religious belief, health and disease: a family perspective
Amount £7,986,970 (GBP)
Organisation The John Templeton Foundation 
Sector Academic/University
Country United States
Start 08/2021 
End 08/2026
 
Description Religious belief, health and disease: a family perspective.
Amount £7,986,970 (GBP)
Funding ID 61917 
Organisation The John Templeton Foundation 
Sector Academic/University
Country United States
Start 08/2021 
End 05/2026
 
Description Research into the longer term effects of COVID-19 in non-hospitalised individuals
Amount £9,593,946 (GBP)
Funding ID COV-LT-0009 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 03/2021 
End 04/2024
 
Description Risky business: Understanding intergenerational persistence in entrepreneurship
Amount £548,327 (GBP)
Funding ID ES/V016660/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 08/2021 
End 09/2024
 
Description Smoking and Vaping Transitions in Early Adulthood: investigating predictors with longitudinal data
Amount £354,821 (GBP)
Funding ID PRCPJT-May21\100007 
Organisation Cancer Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2022 
End 01/2024
 
Description The long term impact of COVID-19 on mental health: comparisons between health record linkage and observed longitudinal data
Amount £11,020 (GBP)
Organisation University of Bristol 
Department Elizabeth Blackwell Institute for Health Research
Sector Academic/University
Country United Kingdom
Start 08/2020 
End 08/2021
 
Description The long term impact of COVID-19 on mental health: comparisons between health record linkage and observed longitudinal data
Amount £11,020 (GBP)
Funding ID R105121-249 
Organisation University of Bristol 
Department Elizabeth Blackwell Institute for Health Research
Sector Academic/University
Country United Kingdom
Start 08/2020 
End 08/2021
 
Description Transaction data for population health
Amount £1,114,169 (GBP)
Funding ID MR/T043520/1 
Organisation Medical Research Council (MRC) 
Sector Public
Country United Kingdom
Start 02/2021 
End 01/2025
 
Description TwinsUK (2019-2023) - An Epidemiological and Genomic Resource
Amount £3,000,000 (GBP)
Funding ID 212904/Z/18/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2019 
End 06/2022
 
Description Understanding the mechanisms linking cities to psychotic experiences across the lifespan
Amount £300,000 (GBP)
Funding ID 218632/Z/19/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2020 
End 04/2024
 
Description Wellcome Longitudinal Population Study COVID-19 Steering Group and Secretariat
Amount £120,585 (GBP)
Funding ID 221574/Z/20/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 06/2020 
End 07/2021
 
Title ALSPAC Biosamples and DNA resources 
Description Over 1.2 million aliquots biosamples taken at various timepoints from ALSPAC participants. The bioresource is available to the scientific community for research. Although the resource was initiated in 1991 it is an active collection with new samples being collected and made available constantly. 
Type Of Material Biological samples 
Provided To Others? Yes  
Impact Samples have been made available for numerous ALSPAC projects. The resource received the UK Biobank of the Year award in 2018 reflecting the impact of studies utalising the samples. 
URL http://www.bristol.ac.uk/alspac/researchers/our-data/biological-resources/
 
Title Deep freeze of ALSPAC datasets 
Description A regular snapshot of our current data is now backed up annually off site. This is in addition to central IT regular back up systems 
Type Of Material Improvements to research infrastructure 
Year Produced 2021 
Provided To Others? No  
Impact Imperative for disaster recovery 
 
Title Development of ALSPAC Explore 
Description ALSPAC Explore is our public facing data catalogue. This is a component of the Obiba Open Source project suite and is hosted by University of Bristol IT services. 
Type Of Material Improvements to research infrastructure 
Year Produced 2021 
Provided To Others? Yes  
Impact Ultimately this tool will improve the discoverability and accessibility of ALSPAC data. The tool has been launched internally and is undergoing testing for external researchers to use as their primary tool for identifying ALSPAC variables. 
URL https://alspac-explore.bristol.ac.uk/mica-web/
 
Title Development of a rapid online survey regarding plans at Christmas 2021 in light of 'Plan B' 
Description ALSPAC was approach by Dr Ellen Brooks-Pollock, UOB and member of SPI-M to rapidly question our participants about their plans over th festive period and determine whether they might change following the Government's announcement of Plan B mitigation emausres 
Type Of Material Improvements to research infrastructure 
Year Produced 2022 
Provided To Others? Yes  
Impact Published on the Government website: https://www.gov.uk/government/publications/university-of-bristol-impact-of-voluntary-risk-mitigation-behaviour-on-the-magnitude-of-a-covid-19-omicron-variant-wave-in-england-11-january-2022 Pre-print and peer reviewed paper to follow alongside a DOI for the data,. 
URL https://www.gov.uk/government/publications/university-of-bristol-impact-of-voluntary-risk-mitigation...
 
Title Development of online consent procedures 
Description In order to facilitate virtual clinics the systems team have successfully tested and implemented the collection of online consent for remote measures. 
Type Of Material Improvements to research infrastructure 
Year Produced 2020 
Provided To Others? No  
Impact Consent is vital for all 'face to face' measures we would normally collect. As we have moved to remote data collection the method for obtaining consent has had to change. 
 
Title Development of virtual online visits 
Description To replace face to face visits in the times of pandemic and to provide an alternative offering to participants who do not want to or cannot attend a clinic visit in person. 
Type Of Material Improvements to research infrastructure 
Year Produced 2021 
Provided To Others? No  
Impact Will minimise attrition. 
 
Title MRI images data pipeline 
Description Streamlined release of re-indexed MRI images on request. 
Type Of Material Improvements to research infrastructure 
Year Produced 2020 
Provided To Others? Yes  
Impact Data note listed below details the data available through the pipeline. This has resulted in reduced cost recovery charges for this data. 
URL https://wellcomeopenresearch.org/articles/5-203
 
Title UK CIC COVID longitudinal sample set 
Description A longitudual set of biological samples including peripheral blood mononuclear cells, plasma and saliva have been collected from cohort members who have had a COVID-19 infection and controls. This resource is available for immunological studies and is linked to new ALSPAC data collected during the pandemic and the longitudinal samples and data collected over 30 years. 
Type Of Material Biological samples 
Year Produced 2021 
Provided To Others? Yes  
Impact The sample collection is complete and analysis of samples is still in progress. Once complete the data generated will be made available alongside data collected from participants during the pandemic and all ALSAPC data including samples collected beofre the pandemic. This will enable research into biomarkers related to infection, recovery and ongoing immunity to COVID-19 and biomarkers pre infection that may predict outcomes of infection. 
 
Title Wellcome LPS COVID Questionnaire bank 
Description The ALSPAC team has led the development of the Wellcome funded Longitudinal Population Studies COVID questionnaire bank. This facilitates comparable research across longitudinal studies. Together with Generation Scotland, ALSPAC form the secretariat for the Wellcome LPS COVID group. ALSPAC has provided the questionnaire in REDCap format on demand 
Type Of Material Improvements to research infrastructure 
Year Produced 2020 
Provided To Others? Yes  
Impact The questionnaire bank facilitates research across multiple studies about the COVID pandemic. The questions were designed to help researchers explore changes using the same validated questions to the lives of cohort participants the UK and elsewhere. 
URL https://www.bristol.ac.uk/alspac/researchers/wellcome-covid-19/
 
Title ARIES-Explorer 
Description ARIES-Explorer provides an openly accessible web interface to explore epigenome-wide methylation data from the Accessible Resource for Integrated Epigenomics Studies 
Type Of Material Database/Collection of data 
Year Produced 2013 
Provided To Others? Yes  
Impact Cited in a key review in the field (Mill et al, Nature Reviews Genetics, VOLUME 14 | AUGUST 2013 | 585). 419 unique visitors to the site in its first month of operation. 
URL http://ariesepigenomics.org.uk/ariesexplorer
 
Title COVID Questionnaire 1 G0 and G1 dataset 
Description Dataset containing Q1 results for G1 and G0 
Type Of Material Database/Collection of data 
Year Produced 2020 
Provided To Others? Yes  
Impact Contribution to our understanding of the impact of the pandemic, particularly mental health 
URL https://wellcomeopenresearch.org/articles/5-127
 
Title COVID Questionnaire 3 and serology results on G0 and G1 
Description Dataset containing Q3 results and results for home antibody testing for G1 and G0 
Type Of Material Database/Collection of data 
Year Produced 2020 
Provided To Others? Yes  
Impact Contribution to our understanding of the impact of the pandemic, based for identifying cases for further study on recuperation and longevity of infection. A data note has just been submitted to Wellcome Open 
 
Title COVID questionnaire 2 G0 and G1 dataset 
Description Dataset containing Q2 results for G1 and G0 
Type Of Material Database/Collection of data 
Year Produced 2020 
Provided To Others? Yes  
Impact Contribution to our understanding of the impact of the pandemic, particularly mental health 
URL https://wellcomeopenresearch.org/articles/5-210
 
Title COVID questionnaire 4 - G0 and G1 
Description Dataset containing Q4 results for G0 and G1 
Type Of Material Database/Collection of data 
Year Produced 2021 
Provided To Others? Yes  
Impact Contribution to our understanding of the impact of the pandemic, based for identifying cases for further study on recuperation and longevity of infection. A data note has been published on Wellcome Open 
URL https://wellcomeopenresearch.org/articles/6-155
 
Title COVID serology testing results in G0 and G1 
Description This study was undertaken in collaboration with ten other LPS. G0 and G1 participants undertook blood sample collection at home. Samples were sent to Thriva and spike protein antibodies were measured 
Type Of Material Database/Collection of data 
Year Produced 2021 
Provided To Others? Yes  
Impact Contribution to our understanding of the impact of the pandemic, basis for identifying cases for further study on recuperation and longevity of infection. A data note has been published on Wellcome Open with further cross-cohort papers underway. 
URL https://wellcomeopenresearch.org/articles/6-283
 
Title Datasets containing indices of Multiple Deprivation (IMD) and other geocoded measures 
Description IMD data has been linked to multiple time points, both on an annual basis (e.g., January 2008, Jan 2009, Jan 2010, etc.), as well as at the time point each child-based ALSPAC questionnaire or clinic was completed/conducted. This has been released all mother and child based data collections 
Type Of Material Database/Collection of data 
Year Produced 2020 
Provided To Others? Yes  
Impact Data to enable research using geocoded SES measures 
 
Title Life@27+; Dataset from questionnaire completed by G1 
Description Data collected at from the 27 year Questionnaire. Infrastructure funded by this award and supplemented with external funding. 
Type Of Material Database/Collection of data 
Year Produced 2021 
Provided To Others? Yes  
Impact Data enabling ongoing research into employment/education and living conditions, events in childhood, mental health, faith and beliefs, and becoming a parent. 
 
Title Life@28+; Dataset from questionnaire completed by G1 
Description Data collected at from the 28 year Questionnaire. Infrastructure funded by this award and supplemented with external funding. 
Type Of Material Database/Collection of data 
Year Produced 2021 
Provided To Others? Yes  
Impact Data enabling ongoing research into ethnicity, hearing, behaviours, substance use, self harm and other mental health issues. 
 
Title Linkage to ALSPAC participants Twitter Social Media Posts 
Description ALSPAC have linked to participants social media posts held on the Twitter Platform. These posts have been downloaded to ALSPAC servers where they have been processed and used with Natural Language Processing algorithms to generate derived variables relating to Mental Health status (e.g. mood, anxiety, depression) and COVID-19 status. These derived variables are now informing applied research projects and will be accessible through the ALSPAC resource. 
Type Of Material Database/Collection of data 
Year Produced 2020 
Provided To Others? Yes  
Impact This dataset is now informing applied research investigations. 
 
Title Linkage to Avon & Wiltshire Partnership Community Mental Health Care records 
Description Linkage to the regional, detailed, community mental health care records of ALSPAC G1 index participants through collaboration with NHS AWP Trust and UK CRIS (University of Oxford). 
Type Of Material Database/Collection of data 
Year Produced 2020 
Provided To Others? Yes  
Impact Supporting a research programme and new funding looking at Mental Health during COVID-19 Pandemic: Linking observed mental health data with record linkage in ALSPAC (ALSPAC Ref: B3602), PI: Alex Kwong, University of Edinburgh. URL: https://proposals.epi.bristol.ac.uk/?q=node/130189 
URL https://www.bristol.ac.uk/alspac/researchers/our-data/linkage/
 
Title Linkage to Public Health England COVID-19 pillar testing data 
Description Linkage to the results of Pillar I and II testing for ALSPAC G1 index participants who have consented and through s2151. Linkage for G0 mothers for those consented only. 
Type Of Material Database/Collection of data 
Year Produced 2021 
Provided To Others? Yes  
Impact Data note has been published on Wellcome Open describing this data and how it has been used to contribute to the identification of COVID-19 cases in the cohort. 
URL https://wellcomeopenresearch.org/articles/6-122
 
Title Parents Family History Questionnaires: Datasets for G0 mothers and fathers 
Description Data collected from the Parents Family History Questionnaires: Infrastructure funded by this award and supplemented with external funding. 
Type Of Material Database/Collection of data 
Year Produced 2021 
Provided To Others? Yes  
Impact Data enabling ongoing inter-generational research. These questionnaires collect data on grandparents and great grandparents including demographic information, smoking, deaths, traumatic childhood events. The URL below provides the link to a data note describing this data published on Wellcome Open 
URL https://wellcomeopenresearch.org/articles/6-115
 
Title Parents Questionnaire 2020: Datasets for G0 mothers and fathers 
Description Data collected from the 2020 Parents Questionnaire: Infrastructure funded by this award and supplemented with external funding. 
Type Of Material Database/Collection of data 
Year Produced 2021 
Provided To Others? Yes  
Impact Data enabling ongoing research into employment/living conditions, physical and mental health, faith and beliefs, and in mothers only, reproductive health and traumatic pregnancy-based experiences 
 
Title Parents' Questionnaire 2018 - Your children and grandchildren; Dataset from questionnaire completed by G0 Mothers 
Description Data collected from the 'Your children and grandchildren' Questionnaire. Infrastructure funded by this award and supplemented with external funding. 
Type Of Material Database/Collection of data 
Year Produced 2020 
Provided To Others? Yes  
Impact Data collected enabling ongoing research into: child behaviour, personality, communication skills, and attention/activity 
 
Title UK LLC: Contribution of ALSPAC data 
Description All COVID-19 based data has been deposited with the UK LLC to facilitate cross-cohort collaboration and linkage to administrative records 
Type Of Material Database/Collection of data 
Year Produced 2021 
Provided To Others? Yes  
Impact None yet. We have not formally received any research proposals as data has only just been made available at the time of writing. 
URL https://ukllc.ac.uk/
 
Title UK10K - population based whole genome sequencing 
Description This is the collection of raw data and results from the UK10K study. By studying and comparing the DNA of 4,000 people whose physical characteristics are well documented, the project aims to identify those changes that have no discernible effect and those that may be linked to a particular disease; by studying the changes within protein-coding areas of DNA that tell the body how to make proteins of 6,000 people with extreme health problems and comparing them with the first group, it is hoped to find only those changes in DNA that are responsible for the particular health problems observed. 
Type Of Material Database/Collection of data 
Year Produced 2012 
Provided To Others? Yes  
Impact This work has been published: Nature. 2015 Oct 1;526(7571):82-90. doi: 10.1038/nature14962. Epub 2015 Sep 14. The UK10K project identifies rare variants in health and disease. UK10K Consortium, Walter K, Min JL, Huang J, Crooks L, Memari Y, McCarthy S, Perry JR, Xu C, Futema M, Lawson D, Iotchkova V, Schiffels S, Hendricks AE,Danecek P, Li R, Floyd J, Wain LV, Barroso I, Humphries SE, Hurles ME, Zeggini E, Barrett JC, Plagnol V, Richards JB, Greenwood CM, Timpson NJ, Durbin R,Soranzo N. 
URL http://www.uk10k.org
 
Title Update to Focusing on You Fathers Questionnaire; Dataset from questionnaire completed by G0 fathers/partners 
Description Data collected from the 'Focusing on You Fathers' Questionnaire. Infrastructure funded by this award and supplemented with external funding. Substantial update with the addition of 483 cases to the dataset. 
Type Of Material Database/Collection of data 
Year Produced 2020 
Provided To Others? Yes  
Impact Data collected enabling ongoing research into: - Home life, neighbourhood, friends and family, employment and finances, mental and physical health, physical activity, gambling behaviour, smoking and alcohol consumption 
 
Title Update to Life@25+; Dataset from questionnaire completed by G1 
Description Data collected at from the 25 year Questionnaire. Infrastructure funded by this award and supplemented with external funding. 
Type Of Material Database/Collection of data 
Year Produced 2020 
Provided To Others? Yes  
Impact Data enabling ongoing research into mental health, personality, behaviour, life events, Eating behaviours & food preferences. Updates: Section B - Strengths and Difficulties; Section C - Anxiety; Question D4 - ADHD medications; Section E - Behaviour; Questions F1 to F7 - Depression and self-harm; Section H - Personality; Section K - Life at Home; and the Friend/Partner Questionnaire 
URL https://alspac-explore.bristol.ac.uk/mica-web/mica/collected-dataset/ype
 
Description 2021/22 Continued NIHR Clinical Research Network West of England collaboration with ALSPAC 
Organisation National Institute for Health Research
Department NIHR Clinical Research Network (CRN)
Country United Kingdom 
Sector Academic/University 
PI Contribution Since 2018/19, the CRN has invested in the ALSPAC team via development bids. CRN portfolio recruitment more than quadrupled from 2018/19 to 2019/20 and has increased again in 2020/21 due to addition of Covid-19 studies (see Table 1). In 2019/2020, the CRN nationally supported more than 6,000 studies and recruited over 732,000 participants, of which ALSPAC alone contributed 11 studies and over 18,000 participants. This contribution helped CRN WE recruit the most participants to public health studies nationally.
Collaborator Contribution CRN WE will be rolling over its budget and allocations from 2020/21 to 2021/22. Therefore, ALSPAC will receive the same financial support as 2020/21, allowing them to extend existing CRN-supported posts. Funds will be allocated to supporting activity such as the: • Development and set-up of REDCap/Teleform data collection systems and consent forms. • Day to day response to REDCap/Teleform issues. • Oversight of contact management system and scheduling of invite and reminder correspondence. ALSPAC has contributed significant and consistently increasing levels of recruitment towards West of England CRN targets in 18/19, 19/20, and 20/21. Four suggested posts to be supported by the ALSPAC allocation in 2021/22.
Impact Study recruitment metrics and output (listed here https://www.bristol.ac.uk/alspac/researchers/publications/) reflect contributions made to engagement and recruitment to the ALSPAC study.
Start Year 2018
 
Description 3D whole body scans, B3495 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description A Consolidator Grant to Study the Developmental Trajectories of Physical and Mental Health Multimorbidity in Genetic High-Risk C (B3439) 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description A Negative Control Analysis Investigating Maternal Smoking, Alcohol consumption and BMI on Molar-Incisor Hypomineralisation, B3679 
Organisation University Hospitals Bristol NHS Foundation Trust
Country United Kingdom 
Sector Hospitals 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description A UK underpinning platform to study immunology and immunopathology of COVID-19: The UK Coronavirus Immunology Consortium, B3547 
Organisation University of Birmingham
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description A deep clinical phenotyping study of a group of participants on a low lung function trajectory, B3947 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2021
 
Description A latent variable approach to examining the role of maternal RSBB in offspring mental health, B3892 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description A robust micro-assay to determine the prevalence of COVID-19 antibodies in the general population using capillary sample collect, B3508 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description ALSPAC (University of Bristol) - Twins UK (KCL) collaboration on developing linkage methodologies 
Organisation St Thomas' Hospital
Department Twins Research Cohorts from St Thomas' Hospital
Country United Kingdom 
Sector Academic/University 
PI Contribution ALSPAC are providing strategic support to develop the TwinsUK record linkage programme based on the established and generalisable approaches developed by the 'PEARL' record linkage team. ALSPAC are specifically 1) supporting the development of the TwinsUK governance approvals based on the precedents of ALSPAC approaches; 2) supporting the development of the TwinsUK data access requests based on the precedents of ALSPAC approaches; 3) will lead the programme to secure GP assent to release copies of patients primary care records to the studies & to develop the technical mechanisms by which this will occur with practice software companies. Further to this, ALSPAC and TwinsUK will collaborate on development of aligned data processing and infrastructure and documentation/discovery developments.
Collaborator Contribution Regular working meetings to develop policy and materials and to share insights.
Impact In December 2019 TwinsUK received a conditional approval from the HRA Confidentiality Advisory Group to access identifiable patient information without explicit patient consent. This was based on ALSPAC's existing approvals.
Start Year 2019
 
Description ALSPAC - Enhancement of Transcriptomic Resources, B3936 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description ALSPAC families (B3370) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2019
 
Description ALSPAC linkage team collaboration with Dr Beng Choon-Ho, University of Iowa Carver College of Medicine. 
Organisation University of Iowa
Department Carver College of Medicine
Country United States 
Sector Academic/University 
PI Contribution The ALSPAC Data Linkage Team are collaborating with Dr Choon-Ho to develop funding applications to support research investigating the neurobiological mechanisms in Adolescent Marijuana Exposure and subsequent Schizophrenia Risk. This will reuse MRI data collected by ALSPAC and Collaborators Professor David and Professor Linden, it will also utilise new data management infrastructure developed by the ALSPAC MRC MH Pathfinder award.
Collaborator Contribution Contributing expertise to grant applications led by Dr Choo-Ho.
Impact 1) Grant application to NIHR (Not supported) "Adolescent Impulsivity, Reward Brain Networks & Schizophrenia Risk" 2) Grant application to NIHR (in progress) "Neurobiological Mechanisms in Adolescent Marijuana Exposure and Schizophrenia Risk"
Start Year 2019
 
Description ALSPAC response to COVID-19 pandemic, B3487 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description Acceptability to participants of novel data linkages, ethical issues, and the practicalities of obtaining consent: Evidence from (B3406) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Adolescent anxiety and depressive symptoms and subsequent intimate partner violence: the impact of mental health support, B3654 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Adolescent insufficient sleep: epigenetic changes and the risk of developing AUD and neuropsychiatric comorbidities, B3641 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Adult peak Circulatory capacity; Mechanisms and Exposures (ACME), B3502 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description Air pollution and childhood asthma: potential role of common allergies as mediators, B3632 
Organisation Bradford Institute for Health Research (BIHR)
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Air pollution exposure and childhood obesity, B3647 
Organisation Barcelona Institute for Global Health
Country Spain 
Sector Multiple 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Air pollution exposure during pregnancy and associations with child gene expression at birth, B3777 
Organisation University of Oslo
Country Norway 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Alcohol 18 to 30, B3507 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description Alcohol Consumption And Hypertensive Disorders of Pregnancy: A Negative Control Analysis In ALSPAC, B3811 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Alcohol use in the late 20's, B3501 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description Allostatic load in childhood and the development of mental health disorders, B3847 
Organisation James Cook University
Country Australia 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Almost exact Mendelian randomisation, B3744 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description An exploration into the impact of social contact on the risk of depressive symptoms during COVID-19: findings from a prospective, B3766 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description An exploration into the links between educational attainment, intelligence and wellbeing, B3783 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description An exploration of the relationship of early-life microbiome patterns and susceptibility to future infections, B3704 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description An individual participant data meta-analysis examining the associations between mode of delivery and respiratory outcomes, B3689 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description An investigation of the environmental effect of parental genotypes on offspring behavioural problems (B3389) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Analysing the association between inflammation and scoliosis in a population-based birth cohort's a proof of concept study (B3404) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Analysis of 3D body scans: genetics of body morphology, correlation with measure of adiposity and cardiometabolic consequences, B3859 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Analysis of developmental relations between co-occurring mental health problems to inform interventions, B3709 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Analyst and writing group member for the MAGIC 'Trans-ethnic meta-analysis and fine-mapping for fasting glucose, fasting insulin, 2hr glucose and HbA1c using data imputed to the 1000 Genomes reference panel 
Organisation MAGIC (The Meta-Analyses of Glucose and Insulin-related traits Consortium)
Country Global 
Sector Charity/Non Profit 
PI Contribution I have contributed results from the analysis of ALSPAC (Avon Longitudinal Study of Parents and Children) data to the meta-analysis. I have acted as a central analyst which has involved conducting quality control checks and reformatting of data contributed by other analysts. I have a led a side project looking at the variance explained by new markers for glycaemic traits. I have contributed to the drafting of the manuscript that will hopefully be submitted shortly.
Collaborator Contribution The other investigators in the collaboration have also contributed results from analyses run within their own cohorts and similarly although variable contributed to side projects and manuscript writing.
Impact A manuscript is in progress but not yet published.
Start Year 2014
 
Description Anorexia and subsequent smoking: cause or correlation (B3355) 
Organisation University of Bristol
Department School for Policy Studies
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Anxiety and mood disorders in young people: a multivariate approach using the ALSPAC cohort, B3464 
Organisation University of Birmingham
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Anxiety symptoms and eating patterns during COVID-19 for young UK adults with different eating behaviour traits, B3775 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Application of co-occurrence networks to the discovery of pre-eclampsia risk, B3786 
Organisation University of Toronto
Country Canada 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Are knee DXA biomarkers related to lower limb biomechanics and gait in women with and without knee osteoarthritis?, B3472 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description Are poorer attendance and oral hygiene behaviours associated with greater dental anxiety in adolescents? B3759 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Assessing and taking account of measurement error using repeat measurements of exposure and outcome variables, B3764 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Assessing individual susceptibility to changes in sleep during the COVID-19 lockdown, B3728 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Assessing the contribution of polygenic risk to pediatric lipid levels and longitudinal trends, B3595 
Organisation Stanford University
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Assessing the hidden gateways into gambling and policies to reduce problem gambling, B3949 
Organisation University of Warwick
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2022
 
Description Assessing young adult e-cigarette use and perceptions, B3707 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Assessing young adult e-cigarette use and perceptions, B3707 
Organisation University of Waterloo
Country Canada 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Assessment of lung function decline in young adults; identifying and characterising early expressions of COPD (B3400) 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2019
 
Description Association between childhood trauma, cognitive styles and depression, B3533 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Association between early infant and young child feeding and BMI Z score trajectory among children under 5 years old, B3816 
Organisation Peking University
Country China 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Association between maternal thyroid dysfunction during pregnancy and thyroid dysfunction in offspring, B3609 
Organisation Hong Kong Polytechnic University
Country Hong Kong 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Association between social disadvantage and children's language and literacy attainments between ages 3-and-9, B3732 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Association of Fat Mass Index (FMI) and DNA methylation - from childhood to adolescence, B3826 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Association of Maternal education with DNA-methylation (B3431) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Association of diet and physical activity with serum metabolites and cardiovascular disease risk in adolescents from the ALSPAC, B3776 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Association of maternal hypothyroidism with bone health in offspring, B3611 
Organisation Hong Kong Polytechnic University
Country Hong Kong 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Association of maternal thyroid dysfunction with cardiometabolic traits in offspring, B3617 
Organisation Hong Kong Polytechnic University
Country Hong Kong 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Association of wheeze phenotypes with lung function using UNICORN cohorts, B3813 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Associations between certainty of COVID-19 infection status and reporting of Long COVID symptoms: the fole of NOCEBO, B3898 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Associations between eating behaviours and body mass index in the ALSPAC cohort at 25, B3483 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Associations between experience of sexual violence, birth experience and perinatal mental health outcomes (B3401) 
Organisation University of Leeds
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Associations between mitochondrial and nuclear DNA variants in human populations, B3881 
Organisation Newcastle University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Associations between physical activity, risk of alcohol-related harm in adolescence: cross-sectional and longitudinal analysis, B3556 
Organisation University of Hull
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Associations between religion and diet, B3893 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Associations between sedentary time and physical activity with arterial function and structure from childhood to adulthood, B3622 
Organisation University of Exeter
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Associations of COVID-19 Risk Perceptions with Mental Health, Wellbeing, and Risk Behaviours, B3579 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Associations of Cardiorespiratory Fitness, Body Composition, Physical Activity and Sedentary Time with Cardiometabolic risks, B3722 
Organisation University of Eastern Finland
Country Finland 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Associations of prospective and retrospective measures of childhood maltreatment with health outcomes, B3746 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Asthma and COVID-19, B3554 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description At the intersection of autism and psychosis: An investigation of causal pathways, developmental trajectories and phenotypic outc, B3477 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Atopic dermatitis, filaggrin null mutations and COVID-119, B3535 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Atopic disease impact on later educational attainment, B3790 
Organisation London School of Hygiene and Tropical Medicine (LSHTM)
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Bidirectional effects of educational attainment/intelligence on brain morphology, B3836 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Big data for reproductive health and wellbeing (B3379) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Biobank Rare Variant Consortium 
Organisation University of Oxford
Department Oxford Hub
Country United Kingdom 
Sector Academic/University 
PI Contribution Consortium of cohort and population based studies with genetics data (rare variants) and deep phenotype data.
Collaborator Contribution Coordination
Impact NA
Start Year 2021
 
Description Biodiversity, inflammation and aversive bodily symptoms, B3874 
Organisation University of the West of England
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Biological markers to study genetics, environment, and how they influence mental health, B3767 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Birth mode impact on social behavior, B3653 
Organisation University of Delaware
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Birth order and cord blood DNA methylation, B3810 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Body Mass Index trajectories across childhood and young adulthood and risk for disordered eating in young adulthood, B3800 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Body muscle and metabolism in middle age, B3498 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Bradford Institute for Health Research and the Born in Bradford Study 
Organisation Bradford Institute for Health Research (BIHR)
Department Born in Bradford
Country United Kingdom 
Sector Public 
PI Contribution Strategic alignment.
Collaborator Contribution Strategic alignment.
Impact na
Start Year 2012
 
Description Brain development in children at high risk of common mental health disorders, B3856 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2021
 
Description Brain signatures of adolescent depression and depression risk (B3421) 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Broad Antisocial Behavior Consortium (BroadABC) - meta-analysis of antisocial phenotypes (B3351) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description CLOSER Data Linkage Network 
Organisation Bradford Institute for Health Research (BIHR)
Department Born in Bradford
Country United Kingdom 
Sector Public 
PI Contribution CLOSER have established a Data Linkage working group for data managers and governance leads. The aim of the working group is to share insights into best practice, discuss emerging opportunities, to share useful materials (precedents, software scripts, data processing protocols) and to work together to help address shared barriers. The working group comprises representatives of the eight CLOSER studies and (to date) the collaborative partners listed above. The need for the group was identified at the 'Preparing for the Future' longitudinal research conference held in 2018.
Collaborator Contribution Contributing insights, precedents and examples of good practice. Knowledge exchange.
Impact 1. Promotion of CLOSER/NHS Digital work led to the Centre for Longitudinal studies changing their approach to onward sharing arrangements with NHS Digital and leading to a successful ammendment to their data sharing contracts. 2. Established contact with the Department for Education to discuss linkage to the Longitudinal Educational Outcome (LEO) dataset. This is furthering understanding of how a linkage arrangements can be designed and implemented.
Start Year 2019
 
Description CLOSER Data Linkage Network 
Organisation Million Women Study
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution CLOSER have established a Data Linkage working group for data managers and governance leads. The aim of the working group is to share insights into best practice, discuss emerging opportunities, to share useful materials (precedents, software scripts, data processing protocols) and to work together to help address shared barriers. The working group comprises representatives of the eight CLOSER studies and (to date) the collaborative partners listed above. The need for the group was identified at the 'Preparing for the Future' longitudinal research conference held in 2018.
Collaborator Contribution Contributing insights, precedents and examples of good practice. Knowledge exchange.
Impact 1. Promotion of CLOSER/NHS Digital work led to the Centre for Longitudinal studies changing their approach to onward sharing arrangements with NHS Digital and leading to a successful ammendment to their data sharing contracts. 2. Established contact with the Department for Education to discuss linkage to the Longitudinal Educational Outcome (LEO) dataset. This is furthering understanding of how a linkage arrangements can be designed and implemented.
Start Year 2019
 
Description CLOSER Data Linkage Network 
Organisation St Thomas' Hospital
Department Twins Research Cohorts from St Thomas' Hospital
Country United Kingdom 
Sector Academic/University 
PI Contribution CLOSER have established a Data Linkage working group for data managers and governance leads. The aim of the working group is to share insights into best practice, discuss emerging opportunities, to share useful materials (precedents, software scripts, data processing protocols) and to work together to help address shared barriers. The working group comprises representatives of the eight CLOSER studies and (to date) the collaborative partners listed above. The need for the group was identified at the 'Preparing for the Future' longitudinal research conference held in 2018.
Collaborator Contribution Contributing insights, precedents and examples of good practice. Knowledge exchange.
Impact 1. Promotion of CLOSER/NHS Digital work led to the Centre for Longitudinal studies changing their approach to onward sharing arrangements with NHS Digital and leading to a successful ammendment to their data sharing contracts. 2. Established contact with the Department for Education to discuss linkage to the Longitudinal Educational Outcome (LEO) dataset. This is furthering understanding of how a linkage arrangements can be designed and implemented.
Start Year 2019
 
Description COVID-19 specific antibody testing in ALSPAC (G0/G1), B3715 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2021
 
Description COVID-19 vaccine effects on the menstrual cycle, B3857 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2021
 
Description COVID-19- Pregnancy, Cardiometabolic health and selection bias, B3543 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Cambridge Cognition online cognitive testing and questionnaire data collection. 
Organisation Cambridge Cognition Ltd
Country United Kingdom 
Sector Private 
PI Contribution Development of online cognitive testing alongside the running of COVID-19 questionnaires within the ALSPAC sampling framework.
Collaborator Contribution Provision of the online material delivery system and incorporation of questionnaire capture within the same testing.
Impact NA
Start Year 2021
 
Description Can heavy menstrual bleeding be used to improve the prediction and prevention of cardiovascular disease in women? B3965 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Can neuroprotective strategies reduced cerebral visual impairment (CVI)? - a pilot study into genetic susceptibility to CVI, B3770 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Can parental education compensate children's genetic disadvantage? B3740 
Organisation Erasmus University Rotterdam
Department Erasmus School of Economics
Country Netherlands 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Cannabis, tobacco and mental illness: isolating their relationship through triangulation of evidence, B3820 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Capturing epigenetic variation in the brain using blood, B3907 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Cardiorespiratory fitness, adiposity, and lean mass in relation to arterial structure and function from childhood to adulthood, B3455 
Organisation University of Eastern Finland
Country Finland 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Causal inference in the study of adverse childhood experiences and adolescent mental health: advancing concepts, methods and evi, B3931 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Causes of Chronic Pain in ALSPAC, B3574 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description Cell type-specific DNA methylation meta-analysis for ADHD symptoms, B3639 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Changes in metabolomic measures attributable to body composition during puberty and young adulthood (B3372) 
Organisation Leiden University
Country Netherlands 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Changing causes and consequences of underweight, overweight, and obesity: a historical comparison of the UK and Norway, 1984-202 (B3441) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Characterisation, determinants, mechanisms and consequences of long COVID - providing the evidence base for health care services, B3666 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description Characterising the ALSPAC mothers who are also UKBiobank participants (B3423) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Characterising trajectories and transitions in tobacco, nicotine and cannabinoid use, and their relationship to mental health, B3499 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description Childcare attendance and age of introductions on respiratory infections, allergy and asthma, B3674 
Organisation Telethon Kids Institute
Country Australia 
Sector Charity/Non Profit 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Childhood adversity, DNA methylation, and risk for depression: A longitudinal study of promoting factors and sensitive periods i, B3870 
Organisation Harvard University
Department Harvard Medical School
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Children's daycare attendance and trajectories of emotional and behavioural symptoms, B3628 
Organisation National Institute of Health and Medical Research (INSERM)
Country France 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Cholesterol trajectories throughout childhood and associations with growth and carotid intima-media thickness, B3815 
Organisation University of Nottingham
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Chronic Airway Diseases Early Stratification (CADSET) (B3446) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Chronic adolescent loneliness: Methods to capture and understand its development,manifestation and experience among young people, B3942 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Clinical Director Designate/ Clinical Co-Director West of England Clinical Research Network 
Organisation National Institute for Health Research
Department NIHR Clinical Research Network (CRN)
Country United Kingdom 
Sector Academic/University 
PI Contribution ALSPAC provides important opportunities for NIHR CRN to contribute to clinically relevant research at a population level. Working with the clinical director of CRN West ALSPAC is able to optimise a contribution to clinical research and to make this viable through support.
Collaborator Contribution The CRN West of England will work with ALSPAC to include studies in the NIHR CRN Portfolio. Inclusion in the portfolio will ensure that studies are supported in their delivery by the CRN West of England clinical research infrastructure in Bristol and across the West of England, including use of the CRN's network of research-active GP practices. Portfolio inclusion will also ensure that the important work of ALSPAC is recognised by the Department of Health and Social Care in regional measures of success in Clinical Research. Support costs funding allocation received: 23/11/2018 Contingency Funding 2018-19 £8,092 21/01/2019 Contingency Funding 2018-19 £9,500 01/04/2019 2019-2020 allocation £32,651
Impact na
Start Year 2018
 
Description Clusters of exposome components and their association with lung function evolution during the youth - REMEDIA project, B3793 
Organisation National Institute of Health and Medical Research (INSERM)
Country France 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Clusters of exposome components and their association with lung function evolution during the youth - REMEDIA project, B3793 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Cognitive ability measures in ALSPAC @ 30 clinic (B3420) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Collaboration with Stephen O'Rahilly and his team at the Wellcome-MRC Institute of Metabolic Science at the University of Cambridge. 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution As part of a wider collaboration to understand the rare genetics of adiposity, we have been working closely with Stephen's group to firstly identify, functionally characterise and describe the downstream adiposity effects of rare genetic variants in the MC4R and MC3R gene regions within the ALSPAC cohort study.
Collaborator Contribution Stephen's group sequenced the MC4R and MC3R gene regions of ~6000 randomly selected ALSPAC participants, of which we have lead the downstream analyses to characterise the relationships between adiposity and related traits.
Impact Two papers have come from this (one that's been accepted in Nature Medicine and one that has been resubmitted to Nature)
Start Year 2019
 
Description Collaboration with the Fatherhood Institute 
Organisation Fatherhood Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Focused research on men and fathers represents a target area for ALSPAC and also a challenge. With little research in this area and the rates of study interaction lower for Men, this collaboration provides focus and an opportunity to expand in this area with the Fatherhood Institute.
Collaborator Contribution The Fatherhood Institute is focused on the gathering of best evidence and research around the role of fathers in the family (and more broadly) and the impact of life course events on the health of fathers. An important relationship between ALSPAC and the Fatherhood Institute has been initiated in order to seek all possible routes to engage with and attract fathers (and men more generally) into the study.
Impact na
Start Year 2018
 
Description Common maternal variants and the occurrence of Cleft in their children, B3683 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Common maternal variants and the occurrence of Cleft in their children, B3683 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Comorbidity of self-harm/suicidal behaviour and substance use in young people, B3833 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Comparison of blood pressure measures for assessing risk of adverse outcomes in pregnancy, B3904 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Comprehensive Prenatal Smoking Assessment and Newborn Methylation, B3809 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Computational approaches to modelling parent -infant behavioural data, B3646 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Consequences of adolescent depression, B3975 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2022
 
Description Consequences of adolescent depression, B3975 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2022
 
Description Consortium Against Pain InEquality (CAPE) - The impact of adverse childhood experiences on chronic pain & responses to treatment, B3678 
Organisation University of Aberdeen
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Contributions of fat and lean mass to blood pressure phenotypes in the young, B3969 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2022
 
Description Contributions of fat and lean mass to structural vascular adaptations in the young, B3968 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2022
 
Description Correlating whooping cough susceptibility and pertussis vaccine immune responses through HLA diversity (B3362) 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Creating ALSPAC polygenic indexes for the SSGAC Polygenic Index Repository, B3842 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Curating UK COVID-19 diagnostics data to catalyse research and innovation 
Organisation University of Nottingham
Country United Kingdom 
Sector Academic/University 
PI Contribution The UK has rich, globally important COVID-19 datasets, including large serology cohort studies funded by UKRI, Wellcome, DHSC/NHS, NIHR and the devolved administrations. However, this breadth of data creates a risk of fragmentation, inconsistent structure and access processes, severely limiting utility, timeliness and impact. "CoCONNECT" is a collaboration looking to transform UK COVID-19 diagnostic datasets to be Findable, Accessible, Interoperable and Reusable (FAIR) and couple this with expert data engineering, enabled by Health Data Research (HDR) UK, to catalyse responsible and trustworthy use of the data for research and innovation. This collaborative work is looking to support the visibility and utility of COVID-19 specific data and resources - such as that contained within ALSPAC. This longitudinal linkage is vital to derive new scientific insights and deliver informed decisions about how best to control the spread of SARS-CoV-2. This follows the realisation in 2020 that there were >30 independent studies with no streamlined approach to linkage to other health and non-health related datasets, lack of data standardisation, and no strategic approach to synthesise analyses across studies.
Collaborator Contribution The key contribution here is two-fold. Firstly the development and implementation of standard data description approaches to ALSPAC COVID-19 data and resources. Secondly, there is the completion of aligned approaches for ALSPAC re. HDRUK Alliance membership and Gateway display. This is a key development which is - at this time - based on COVID-19 data, but which will go on to be relevant for ALSPAC data made accessible through the HDRUK Gateway.
Impact NA
Start Year 2020
 
Description Curating UK COVID-19 diagnostics data to catalyse research and innovation, B3634 
Organisation University of Nottingham
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description DNA methylation indices of cancer risk factors, B3660 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description DNA methylation signatures of aggressive behavior (B3405) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description DPUK and Cambridge Cognition data collection (cognition) as part of remote data collection (ALSPAC) and DPUK 
Organisation Cambridge Cognition Ltd
Country United Kingdom 
Sector Private 
PI Contribution A relationship between Ian Penton-Voak, Marcus Munafo, ALSPAC and Jenny Barnett - Cambridge Cognition using ALSPAC to generate cognitive data remotely for DPK.
Collaborator Contribution Cambridge Cognition is a Cambridge-based SME that is the leading global provider of cognitive assessment software for clinical trials, academic research and healthcare provision. It has recently funded a Research Hub at the University of Bristol. This will facilitate data collection planned with DPUK as part of the remote data collection initiative over the next funding window in ALSPAC.
Impact na
Start Year 2018
 
Description Daily mental health symptoms in high risk depression groups: a feasibility EMA study, B3890 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data & Secondary Analysis
Impact None yet
Start Year 2021
 
Description Data Note-ALSPAC participants and the Bristol Self-Harm Register, B3883 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Data collection: measurement and correlates of internalized weight stigma, B3748 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2021
 
Description Deep phenotyping of cardiovascular systems physiology in adults born to hypertensive pregnancies, B3613 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description Defining association of early life infection with differences in cellular composition of blood samples, B3896 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Dementias Platform UK - John Gallacher 
Organisation University of Oxford
Department Department of Psychiatry
Country United Kingdom 
Sector Academic/University 
PI Contribution Strategic alignment with DPUK in order to (i) test the use of DPUK/UKSeRP data release pathways (for all data rather than just linkage) and to work collaboratively on the use of Cambridge Cognition remote cognitive testing barrage; (ii) examine and extend the application of federated linkage across studies contained within the UKSeRP infrastructure.
Collaborator Contribution The collection of cognition data (remotely) through the deployment of Cambridge Cognition based cognitive testing. Data collection is provided by the collaboration along with the automatic "piping" of data to DPUK secure repositories within the UKSeRP framework (SAIL).
Impact na
Start Year 2018
 
Description Depositing data with DPUK: a trial dataset, B3619 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Depressive symptoms from childhood to adulthood, B3663 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Depressogenic thinking in adolescence and depressive mood across early adulthood, B3534 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Describing the ALSPAC religiosity data and identifying potential confounders, B3911 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Determinants of social inequalities in respiratory health: Findings from the EU Child Cohort Network, B3861 
Organisation University of Copenhagen
Country Denmark 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Developing a olfactory-like biosensor for urine diagnostics (B3422) 
Organisation Rosa Biotech Limited
Country United Kingdom 
Sector Private 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Development of mental illness and cardiometabolic comorbidities, B3702 
Organisation University of Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Development of standardised virus pseudotype assay to quantify SARS-CoV-2 neutralising antibodies in saliva and serum, B3869 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Developmental Origins of Health and Disease as mediated and moderated by social determinants within the family, B3510 
Organisation Syracuse University
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Developmental origins of thyroid function regulation in the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort, B3905 
Organisation National Center for Scientific Research (Centre National de la Recherche Scientifique CNRS)
Country France 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Developmental pathways to mental health problems, B3840 
Organisation University of Oslo
Country Norway 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Developmentally-induced DNA methylation changes in response to maternal tobacco and cannabis use during pregnancy, B3899 
Organisation University of Canterbury
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Diagnostic prediction model for coeliac disease, B3685 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Dietary intake throughout childhood and adolescence with cardiometabolic health in later life (B3388) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Differential Impact of COVID on Children born preterm, B3763 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Discovering the person behind the data: Assembling and validating vulnerable children's life histories from quantitative data, B3492 
Organisation University of Sussex
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description Disease risk prioritisation in early life using polygenic risk profiles, B3943 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Disease risk prioritisation in early life using polygenic risk profiles, B3943 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2022
 
Description Dissect the interaction of age at first marriage and associated sociological traits with a genetic approach (B3380) 
Organisation University of Wisconsin-Madison
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Dissecting PCOS Physiology by Defining Phenotypes Associated with PCOS Genetic Risk Factors in Children, B3581 
Organisation Boston Children's Hospital
Country United States 
Sector Hospitals 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Do Religious Behaviours and Beliefs Impact Study Participation, B3906 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Do asthma and ADHD have shared developmental origins? B3569 
Organisation Queen Mary University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Do childhood ADHD symptoms predict anxiety disorders in adolescence? B3755 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Do poverty-reduction fiscal policies reduce childhood obesity? A study based on microsimulations and scenario evaluations, B3608 
Organisation University of Turin
Country Italy 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Do women's expectations impact their birth experience and health outcomes? (B3364) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Does Fetal Alcohol Spectrum Disorders (FASD) classification predict engagement in adolescent Multiple Risk Behaviours (MRBs)? B3903 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Does attachment style in childhood predict mental health difficulties in early adulthood? B3572 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Does following a vegetarian/vegan/plant-based diet during pregnancy causally affect the health of offspring? B3626 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Does opting in or out affect the take up of incentives in a long running population-based cohort study: A nested randomised trial, B3662 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Does sleep quality and quantity during the early years having lasting effects on educational outcomes? B3677 
Organisation Centre for Applied Education Research
Sector Charity/Non Profit 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Does socioeconomic position modify associations between grandparental body composition and that of the grandchildren? (B3425) 
Organisation Aarhus University
Country Denmark 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Does socioeconomic status moderate the relationship between adolescent drug use and mental health? B3798 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Does the Timing of Menarche Affect the Development of Eating Disordered Behaviour, B3559 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description EMBED, B3758 
Organisation Romanian Academy
Country Romania 
Sector Public 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description EWAS of Green Spaces - LifeCycle, B3549 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Early Childhood Shyness, Psychosocial Experiences, and Trajectories of Cardiovascular Risk Factors across the Life-Course (B3381) 
Organisation University of Maryland
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Early Environmental quality and life-course mental health effects (EQUAL-LIFE): Internal Exposome (WP2), B3902 
Organisation University of Eastern Finland
Country Finland 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Early life exposure to cardiovascular risk factors and cerebral structure and function in young adults, B3665 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Early metabolic features of adiposity-related cancer susceptibility, B3538 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Early metabolic features of breast cancer susceptibility, B3757 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Early signs and predictors of ADHD. A population cohort study, B3590 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Early-life determinants of peak muscle function in adulthood (B3387) 
Organisation Manchester Metropolitan University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2019
 
Description Early-life factors for elevated blood pressure later in life, B3845 
Organisation Zhejiang University
Country China 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Eating disorders and anxiety: Mapping developmental trajectories and their genetic underpinnings (B3382) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2019
 
Description Eating disorders and anxiety: Mapping developmental trajectories and their genetic underpinnings (B3382) 
Organisation University of Geneva
Country Switzerland 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2019
 
Description Effect of adverse childhood experiences on adolescent depression, anxiety and self harm: An analysis in the ALSPAC cohort, B3536 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Effect of being a persistent picky eater on eating behaviour in school-aged children, B3712 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Effects of adolescent physical activity on physical and mental health in adulthood: novel multivariate pattern analysis approach, B3659 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Effects of feeding practice on children's eating behavior and weight growth, B3509 
Organisation Peking University
Country China 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Egton Medical Informatics Systems (EMIS) - Development of a harmonised standard and extraction tool for primary care data into longitudinal studies. 
Organisation EMIS Group
Country United Kingdom 
Sector Private 
PI Contribution ALSPAC with Born In Bradford and UK Biobank have established a harmonised standard for primary care data extracts optimised for longitudinal studies. EMIS Ltd are working to develop this into a clinical software grade software standard and to operationalise it in the EMIS primary care system platform (>50% market share within English GP practices).
Collaborator Contribution EMIS are bringing their considerable experience of managing primary care records and developing software extraction processes and data transformations. This experience will bring technical and data quality insights to the proposed standard. EMIS will also facilitate the collection of GP assents for data collection and extraction by longitudinal studies.
Impact The extraction software standard and mechanism are currently in development.
Start Year 2018
 
Description Emotional dysregulation, self-harm and eating disorders: a mechanistic investigation (B3395) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Engagement, recruitment and monitoring of participation - Qualitative Research Integrated within Trials (QuinteT) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution ALSPAC will work with QuinteT to deploy qualitative methods used to monitor and maximise recruitment in randomised controlled trials in ALSPAC.
Collaborator Contribution This will be focused on the recruitment activity around ALSPAC_30 clinic visits and will be run both before and during the recruitment process given the nature of the open clinic.
Impact na
Start Year 2018
 
Description Environment, DNA methylation and risk of childhood acute lymphoblastic leukaemia: a novel two-sample MR study, B3511 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Environment-wide association study for adiposity in ALSPAC (B3383) 
Organisation University of Hong Kong
Country Hong Kong 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Environmental exposures in pregnancy and early life influencing cognitive and cardio-respiratory development (B3412) 
Organisation University of Leicester
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description EpiTIME: Solving the 'time puzzle' of epigenetic effects on child mental health (B3361) 
Organisation King's College London
Department Department of Child & Adolescent Psychiatry
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Epidemiological and genomic relationship, and pleiotropic mechanisms across complex traits, B3768 
Organisation Westlake University
Country China 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Epigenetic prediction of pubertal timing, B3690 
Organisation University of Texas at Austin
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Epigenetic trajectories of mental health (B3428) 
Organisation University of Bath
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2019
 
Description Epigenetics of changing traits, B3967 
Organisation National University of Ireland, Galway
Country Ireland 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2022
 
Description Epigenome-wide association study of depression and antidepressant use, B3818 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Epigenome-wide association study of handedness, B3694 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Estimate the causal effect of maternal smoking during pregnancy on offspring's birth weight using ALSPAC data, B3977 
Organisation University of Michigan
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2022
 
Description Estimated Prevalence and Stability of Nonverbal Learning Disability, B3649 
Organisation Columbia University Medical Center
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description European resource for research into the early life origins of asthma, allergy, and eczema across the life course. EU Child Cohort, B3717 
Organisation Erasmus University Rotterdam
Department Generation R Study
Country Netherlands 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Evaluating diet at age 30 (ALSPAC-G1) (B3376) 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2019
 
Description Evaluating longitudinal invariance in measures of child and adolescent mental health and wellbeing across development, B3658 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Evaluating longitudinal invariance in measures of child and adolescent mental health and wellbeing across development, B3658 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Evaluating the effect of school closures during the COVID-19 pandemic: A natural experiment in South Korea, B3795 
Organisation Seoul National University
Country Korea, Republic of 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Evaluation of recording of Long-COVID in whole population databases using linked LPS data, B3756 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Examining patterns and predictors of mental health during and in response to COVID-19, B3506 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Examining the association between alcohol use, cognitive functioning and self-harm (B3437) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Examining the association between childhood bilingualism and cognitive functioning in adulthood, B3500 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Examining the genetic architecture of depression in and around pregnancy in the ALSPAC study, B3806 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Examining the relationship between leptin levels in childhood and lifetime anorexia nervosa using observational and genetic epid, B3923 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Exercise and Mental Health in Children with Neurodevelopmental Conditions, B3725 
Organisation University of York
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Exome sequencing of ALSPAC children and parents, B3565 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exploration of the relationship between social cognition and PTSD within the ALSPAC cohort, B3474 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exploratory ML Based Longitudinal Modelling Approaches to Map Genetic-Phenotypic Multi-Trait Predictors of Fibrosis, B3799 
Organisation Boehringer Ingelheim
Country Germany 
Sector Private 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Exploring candidate gene mechanisms in atopic eczema (B3453) 
Organisation University of Dundee
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exploring causal effects of health behaviours on mental health and wellbeing, B3456 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exploring epigenetic and phenotypic associations with genetic liability to juvenile idiopathic arthritis, B3669 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exploring how much complex trait variation is captured by DNA methylation in epigenome-wide association studies, B3561 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exploring intergenerational risk transmission using network analysis, B3852 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Exploring self-harm and disordered eating as risk factors for poorer mental health during the COVID-19 pandemic, B3562 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exploring shared genetic associations between risk behaviours and educational attainment, B3557 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exploring the association between chronic pain and academic achievement in a UK cohort, B3834 
Organisation Queen's University Belfast
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Exploring the associations between ADHD symptoms, mental health and higher education, B3789 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Exploring the associations between paternal postnatal depression, aspects of involvement and parenting and child development , B3516 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exploring the effects of twin birth and prematurity on school readiness and early academic outcomes (B3454) 
Organisation Bradford Institute for Health Research (BIHR)
Department Born in Bradford
Country United Kingdom 
Sector Public 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exploring the impact of Autism Spectrum Disorder Traits on symptoms of depression and anxiety during the COVID-19 pandemic, B3955 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Exploring the progression of mental illness: Identifying predictors of recovery, B3591 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exploring the text data provided by participants completing the COVID Q, B3529 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exposure to carbon monoxide in pregnancy and postnatally and neurocognitive effects on the child - a secondary data analysis, B3629 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Exposure to green and blue spaces and working memory in children aged 5-12, B3730 
Organisation University of the Basque Country
Country Spain 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Exposure to urban natural environments and birth outcomes, B3648 
Organisation Barcelona Institute for Global Health
Country Spain 
Sector Multiple 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Factors associated with third molar pathology and treatment in a representative population, B3482 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Family background and the intergenerational transmission of educational attainment: A multi-cohort analysis, B3539 
Organisation Duke University
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Fasting insulin GWAS, B3491 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Father absence, children's genetic make-up and outcomes, B3742 
Organisation Erasmus University Rotterdam
Department Erasmus School of Economics
Country Netherlands 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Feasibility assessment of RNA sequencing of blood spots, B3731 
Organisation University of California, Los Angeles (UCLA)
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Financial Stress and Smoking Behaviour, B3735 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Fine-mapping of vascular reactivity loci using human artery multi-omics analyses, B3523 
Organisation University of Virginia (UVa)
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Fit body, fit mind? The relationship between cardiorespiratory fitness and muscular strength during adolescence with future risk, B3759 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Food frequency questionnaire validation study, B3875 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2021
 
Description From Social Cognitive Deficits to Later Emotional and Behavioural Problems: The Roles of Cortisol and Inflammatory Cytokines, B3681 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description G1 Addition of lung function to G1 clinic @30 (B3393) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2019
 
Description G1 Substance Use questions for the next sweep, B3599 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description GWAS of age of peak velocity of depressive symptoms and investigation of associated variables, B3657 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description GWAS of breast density (B3356) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description GWAS on longitudinal pubertal traits in Chilean adolescents, B3633 
Organisation Adolfo Ibáñez University
Country Chile 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Gambling data collection @30, B3886 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data & Secondary Analysis
Impact None yet
Start Year 2021
 
Description Gene-environment interactions in mental health trajectories of youth, B3879 
Organisation Maastricht University (UM)
Country Netherlands 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Gene-gene, gene-environment interaction and risk prediction of pediatric mental disorders: multi-omics data analysis of ALSPAC, B3917 
Organisation Nanjing Medical University
Country China 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Genetic Covariation Between Alcohol Use, Aggression, ADHD, and Executive Function Across Early Adolescence and Young Adulthood, B3823 
Organisation University of Missouri
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Genetic and Environmental Components of Parental Effects on Child Physical and Mental Health, B3465 
Organisation University of Hong Kong
Country Hong Kong 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Genetic and non-genetic influences on the development of psychiatric outcomes in children born with cleft lip and/or palate, B3578 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Genetic determinants of distinct body mass index trajectories to young-adulthood obesity, B3910 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Genetic determinants of neonatal hyperbilirubinemia, B3606 
Organisation University of Amsterdam
Country Netherlands 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Genetic impact on youth vaping: extending known genetic risk factors in smoking to vaping, B3593 
Organisation University of Toronto
Country Canada 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Genetic influences on infant and childhood growth, B3605 
Organisation University of Bergen
Country Norway 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Genetic risk for Alzheimers disease and the metabolome across the life course, B3695 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Genetics of Stuttering, B3620 
Organisation Max Planck Society
Department Max Planck Institute for Psycholinguistics
Country Germany 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Genetics, Adverse Childhood Experiences (ACEs), and Developmental and Behavioral Outcomes, B3652 
Organisation University of Cincinnati
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Genome wide association study of progression from impaired fasting glucose to type 2 diabetes, B3872 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Genome-wide association studies of prenatal depression in ALSPAC (B3448) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Genome-wide association study of bone mineral density in ALSPAC children and mothers, B3978 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2022
 
Description Genome-wide association study of menstruation-related traits, B3782 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Genome-wide meta-analysis of infant developmental milestones and temperament (B3360) 
Organisation Birkbeck, University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Genomic determinants of Multiple Sclerosis susceptibility in an ethnically diverse population, B3571 
Organisation Queen Mary University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Gestational Age at Birth and Childhood Body Size, B3738 
Organisation University of Copenhagen
Country Denmark 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Global Lung Function Initiative Exhaled Nitric Oxide (FENO) Data Request, B3865 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Green Spaces and Multiple Child Health Outcomes /Air pollution exposure and childhood obesity/Nature and birth outcomes, B3625 
Organisation Barcelona Institute for Global Health
Country Spain 
Sector Multiple 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Green Spaces and Multiple Child Health Outcomes, B3625 
Organisation Barcelona Institute for Global Health
Country Spain 
Sector Multiple 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Green space and child cardiometabolic health: A structured life course approach, B3930 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Growing up in deprivation or threat: A network decision tree approach to the timing of early adversity, B3729 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description HDR-UK South West Better Care Partnership, B3521 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description HMOX1 imputation, testing and impact on outcomes, B3801 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Harnessing genetics to understand the role of DNA methylation in healthy aging, B3603 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description Health and wellbeing in surviving congenital heart disease patients, B3530 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description High neighbourhood-level deprivation, collective efficacy and conduct disorder behaviours: A network analysis, B3964 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Home Biome project (DUsty SecreTs - DUST), B3588 
Organisation Northumbria University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2020
 
Description Host genetic effects on COVID-19 susceptibility and outcomes, B3520 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description How Locus of Control affected well-being during the Pandemic, B3835 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description How do early-life factors explain adverse metabolic outcome in children and adolescents: A causal mediation analysis, B3794 
Organisation Isfahan University of Medical Sciences
Country Iran, Islamic Republic of 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description How the interaction of genetic and environmental factors influences human traits, B3863 
Organisation EMBL European Bioinformatics Institute (EMBL - EBI)
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Hypersensitivities and Aversions across the 5-senses, B3714 
Organisation University of Sussex
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2021
 
Description Hypertensive disorders of pregnancy and cognition, B3614 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Hypothesis-free and pQTL analysis of deep vein thrombosis aetiology: a Mendelian randomization study (B3432) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2019
 
Description Identification of genetic determinants of dietary intakes by prioritizing obesity-related variants highly expressed in the brain, B3636 
Organisation Harvard University
Department Harvard T.H. Chan School of Public Health
Country United States 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2020
 
Description Identifying clusters of Long COVID symptoms, B3871 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Identifying genetic and environmental factors underpinning complex trait variation in humans, B3841 
Organisation Westlake University
Country China 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Identifying genetic variants predisposing to overeating behaviour (B3407) 
Organisation Brunel University London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2019
 
Description Identifying genetic variants predisposing to overeating behaviour (B3407) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2019
 
Description Identifying markers for brain signatures of adolescent depression and depression risk, B3860 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Identifying psychiatric risk factors for body dysmorphic disorder, B3796 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2021
 
Description Identifying risk factors for adverse mental health outcomes in orofacial cleft and optimising interventions to avoid these, B3781 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Identifying the genetic markers associated with within-individual variability in blood pressure, B3950 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2021
 
Description Immuno-Metabolic Predictors of Anhedonic Depression and Treatment Response: The IMPACT Programme, B3877 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution New Data and Secondary Analysis
Impact None yet
Start Year 2021
 
Description Impact of exposome on the course of lung diseases, B3291 
Organisation National Institute of Health and Medical Research (INSERM)
Country