The Avon Longitudinal Study of Parents and Children: An international resource for population genomics and lifecourse epidemiology. Core Programme Support 2011-2015 and Core programme support 2014-2019
Lead Research Organisation:
Wellcome Trust
Department Name: UNLISTED
Abstract
For over 20 years Children of the 90s (or ALSPAC) has charted the health of 14,500 parents and
children. Now in its third decade it has started to study the next generation, the children of the
Children of the 90s. The study is unequalled by other population studies because of the breadth
and depth of information it holds on participants from before birth over 20 years ago through to the
present day. It is internationally renowned and used by researchers worldwide. The data allow
researchers to study key periods of development, how certain conditions develop and change over
time and are passed (or not) from one generation to the next, and how health is affected by the
interplay between genes and other factors like smoking, where people live and the job they do.
Our goals are to ensure the resource remains sustainable and open to researchers to use, and
that participants remain engaged. We will continue to gather information from the original children
through clinical assessments, questionnaires and record linkage, and will be recruiting and
gathering data on the children of the children as well as merging genetic data and enhancing research in the exciting new field of epigenomics.
children. Now in its third decade it has started to study the next generation, the children of the
Children of the 90s. The study is unequalled by other population studies because of the breadth
and depth of information it holds on participants from before birth over 20 years ago through to the
present day. It is internationally renowned and used by researchers worldwide. The data allow
researchers to study key periods of development, how certain conditions develop and change over
time and are passed (or not) from one generation to the next, and how health is affected by the
interplay between genes and other factors like smoking, where people live and the job they do.
Our goals are to ensure the resource remains sustainable and open to researchers to use, and
that participants remain engaged. We will continue to gather information from the original children
through clinical assessments, questionnaires and record linkage, and will be recruiting and
gathering data on the children of the children as well as merging genetic data and enhancing research in the exciting new field of epigenomics.
Technical Summary
The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective cohort study with
unprecedented scope and detail of information on thousands of people from before birth through
to early adulthood, on their parents and now on their children. It is an internationally valued
resource at the forefront of population-based research. ALSPAC allows the investigation of
developmental trajectories marking critical periods in human life, the genetic and epigenetic
factors contributing to health and disease and the environmental exposures which form the context
within which these processes act. As ALSPAC participants enter adulthood and start having
children, the study's potential to contribute to scientific discovery is expanding, giving a greater
capacity to explore links between current and future health and the intergenerational components
of health and disease. ALSPAC is unequivocally the richest open-access epidemiological resource
in the world. Our goals are to ensure that ALSPAC (i) is sustained, (ii) has participation maximised
and (iii) is enhanced. These goals will be delivered by follow-up of the original cohort through clinic
assessment, questionnaires and record linkage, data collection on their children, consolidation of
GWAS data on all participants and the development of epigenomics research.
unprecedented scope and detail of information on thousands of people from before birth through
to early adulthood, on their parents and now on their children. It is an internationally valued
resource at the forefront of population-based research. ALSPAC allows the investigation of
developmental trajectories marking critical periods in human life, the genetic and epigenetic
factors contributing to health and disease and the environmental exposures which form the context
within which these processes act. As ALSPAC participants enter adulthood and start having
children, the study's potential to contribute to scientific discovery is expanding, giving a greater
capacity to explore links between current and future health and the intergenerational components
of health and disease. ALSPAC is unequivocally the richest open-access epidemiological resource
in the world. Our goals are to ensure that ALSPAC (i) is sustained, (ii) has participation maximised
and (iii) is enhanced. These goals will be delivered by follow-up of the original cohort through clinic
assessment, questionnaires and record linkage, data collection on their children, consolidation of
GWAS data on all participants and the development of epigenomics research.
Organisations
- Wellcome Trust (Lead Research Organisation)
- Duke-NUS Graduate Medical School (Collaboration)
- University of Granada (Collaboration)
- The Hospital for Sick Children (SickKids) (Collaboration)
- UNIVERSITY OF READING (Collaboration)
- Lausanne University Hospital (CHUV) (Collaboration)
- Massachusetts General Hospital (Collaboration)
- Chungnam National University (Collaboration)
- Norwegian University of Science and Technology (NTNU) (Collaboration)
- University of Vienna (Collaboration)
- McMaster University (Collaboration)
- Cincinnati Children's Hospital Medical Center (Collaboration)
- Murdoch Children's Research Institute (Collaboration)
- EMIS Group (Collaboration)
- Emory University (Collaboration)
- UNIVERSITY OF BIRMINGHAM (Collaboration)
- Norwegian Institute of Public Health (Collaboration)
- Medical University of South Carolina (Collaboration)
- European Molecular Biology Laboratory (Collaboration)
- City University of Hong Kong (Collaboration)
- Utrecht University (Collaboration)
- Columbia University (Collaboration)
- UNIVERSITY OF SYDNEY (Collaboration)
- University of Pittsburgh (Collaboration)
- Aarhus University (Collaboration)
- Villanova University (Collaboration)
- Lancaster University (Collaboration)
- UNIVERSITY HOSPITALS BRISTOL NHS FOUNDATION TRUST (Collaboration)
- University of London (Collaboration)
- Erasmus MC (Collaboration)
- Bristol City Council (Collaboration)
- Westlake University (Collaboration)
- University of Hull (Collaboration)
- Birkbeck, University of London (Collaboration)
- University of Pennsylvania (Collaboration)
- UNIVERSITY OF OXFORD (Collaboration)
- University of Maryland, College Park (Collaboration)
- University of Texas at Austin (Collaboration)
- New York State Office of Mental Health (Collaboration)
- BRUNEL UNIVERSITY LONDON (Collaboration)
- University of Tasmania (Collaboration)
- International Agency for Research on Cancer (IARC) (Collaboration)
- Millennium Cohort Study (MCS) (Collaboration)
- Yale University (Collaboration)
- UNIVERSITY OF DUNDEE (Collaboration)
- James Cook University (Collaboration)
- Korea University (Collaboration)
- Eberhard Karls University of Tübingen (Collaboration)
- Shanghai Jiao Tong University (Collaboration)
- ST GEORGE'S UNIVERSITY OF LONDON (Collaboration)
- Uppsala University (Collaboration)
- Penn State University (Collaboration)
- Sichuan University (Collaboration)
- University of Laval (Collaboration)
- Massey University (Collaboration)
- Our Future Health (Collaboration)
- Boston Children's Hospital (Collaboration)
- Simon Fraser University (Collaboration)
- University of Adelaide (Collaboration)
- UNIVERSITY OF LIVERPOOL (Collaboration)
- Concordia University (Collaboration)
- Quadram Institute Bioscience (Collaboration)
- National Institute for Health Research (Collaboration)
- University of California, Los Angeles (UCLA) (Collaboration)
- IMPERIAL COLLEGE LONDON (Collaboration)
- University of California, Davis (Collaboration)
- OXFORD BROOKES UNIVERSITY (Collaboration)
- University of Turin (Collaboration)
- Duke University (Collaboration)
- University of Memphis (Collaboration)
- ROSA BIOTECH LIMITED (Collaboration)
- University Hospital Erlangen (Collaboration)
- University of Manitoba (Collaboration)
- University of Göttingen (Collaboration)
- QIMR Berghofer Medical Research Institute (Collaboration)
- Hunter Medical Research Institute (Collaboration)
- Loyola University (Collaboration)
- Indiana University (Collaboration)
- COVENTRY UNIVERSITY (Collaboration)
- Karolinska Institute (Collaboration)
- University of York (Collaboration)
- University of California, San Francisco (Collaboration)
- Parc Sanitari Sant Joan de Déu (Collaboration)
- University of Warwick (Collaboration)
- UNIVERSITY OF STRATHCLYDE (Collaboration)
- Leiden University Medical Center (Collaboration)
- EMBL European Bioinformatics Institute (EMBL - EBI) (Collaboration)
- Oregon Health and Science University (Collaboration)
- The Open University (Collaboration)
- University of Bath (Collaboration)
- NHS South, Central and West Commissioning Support Unit (Collaboration)
- Sinai Health System (Collaboration)
- Evolyst (Collaboration)
- Seoul National University (Collaboration)
- MAGIC (The Meta-Analyses of Glucose and Insulin-related traits Consortium) (Collaboration)
- UNIVERSITY OF ESSEX (Collaboration)
- Fudan University (Collaboration)
- University of Stirling (Collaboration)
- UNIVERSITY OF SOUTHAMPTON (Collaboration)
- NORTH BRISTOL NHS TRUST (Collaboration)
- Florey Institute of Neuroscience and Mental Health (Collaboration)
- HARVARD UNIVERSITY (Collaboration)
- University of Wisconsin-Madison (Collaboration)
- National Institute of Health and Medical Research (INSERM) (Collaboration)
- Cambridge Cognition Ltd (Collaboration)
- UK CENTRE FOR ECOLOGY & HYDROLOGY (Collaboration)
- Royal Holloway, University of London (Collaboration)
- Columbia University Medical Center (Collaboration)
- Dalhousie University (Collaboration)
- University of South Carolina (Collaboration)
- Romanian Academy (Collaboration)
- University of Strasbourg (Collaboration)
- British Geological Survey (Collaboration)
- ULSTER UNIVERSITY (Collaboration)
- University of Saskatchewan (Collaboration)
- MANCHESTER METROPOLITAN UNIVERSITY (Collaboration)
- UNIVERSITY OF NEWCASTLE (Collaboration)
- Liverpool John Moores University (Collaboration)
- Telethon Kids Institute (Collaboration)
- Erasmus University Rotterdam (Collaboration)
- University of Toronto (Collaboration)
- SWANSEA UNIVERSITY (Collaboration)
- UNIVERSITY OF BRADFORD (Collaboration)
- UNIVERSITY OF BRITISH COLUMBIA (Collaboration)
- University of Eastern Finland (Collaboration)
- University of Glasgow (Collaboration)
- Vilnius University (Collaboration)
- Washington University in St Louis (Collaboration)
- University at Buffalo (Collaboration)
- University College Dublin (Collaboration)
- University of Oslo (Collaboration)
- Food and Drug Administration (FDA) (Collaboration)
- University of Groningen (Collaboration)
- Metabolon Inc (Collaboration)
- University of Macau (Collaboration)
- Hong Kong Polytechnic University (Collaboration)
- Max Planck Society (Collaboration)
- Barcelona Institute for Global Health (Collaboration)
- University of Auckland (Collaboration)
- University of the Witwatersrand (Collaboration)
- Chinese University of Hong Kong (Collaboration)
- University of Queensland (Collaboration)
- Thames Valley Police (Collaboration)
- University of Iowa (Collaboration)
- Leibniz Institute for Prevention Research and Epidemiology - BIPS (Collaboration)
- University of Arizona (Collaboration)
- National Taiwan University (Collaboration)
- University College London (Collaboration)
- Federal University of Bahia (Collaboration)
- Virginia Commonwealth University (Collaboration)
- University of Bergen (Collaboration)
- State University of New York (Collaboration)
- University of North Carolina at Chapel Hill (Collaboration)
- NORTHUMBRIA UNIVERSITY (Collaboration)
- Brigham and Women's Hospital (Collaboration)
- Delft University of Technology (TU Delft) (Collaboration)
- Maastricht University (UM) (Collaboration)
- University of Rochester (Collaboration)
- Lovisenberg Diakonale Hospital (Collaboration)
- Boehringer Ingelheim (Collaboration)
- University of Illinois Urbana-Champaign (Collaboration)
- University of Leuven (Collaboration)
- TrygFonden (Collaboration)
- University of Washington (Collaboration)
- Stetson University (Collaboration)
- Bergen University College (Collaboration)
- Drexel University (Collaboration)
- Olink AB (Collaboration)
- University of Zurich (Collaboration)
- Zhejiang University (Collaboration)
- LOUGHBOROUGH UNIVERSITY (Collaboration)
- KEELE UNIVERSITY (Collaboration)
- University of Calgary (Collaboration)
- Case Western Reserve University (Collaboration)
- University of Surrey (Collaboration)
- University of Minnesota (Collaboration)
- National Research Council (Collaboration)
- NHS GRAMPIAN (Collaboration)
- University of Santiago, Chile (Collaboration)
- NYU Langone Medical Center (Collaboration)
- Gastroenterology Hospital "Saverio de Bellis" (Collaboration)
- Vanderbilt University (Collaboration)
- Nottingham Trent University (Collaboration)
- Orygen (Collaboration)
- University College Cork (Collaboration)
- Walden University (Collaboration)
- University of the Basque Country (Collaboration)
- Johns Hopkins University (Collaboration)
- Hannover Medical School (Collaboration)
- Stanford University (Collaboration)
- Icahn School of Medicine at Mount Sinai (Collaboration)
- Pasteur Institute, Paris (Collaboration)
- University of Amsterdam (Collaboration)
- Medical Research Council (MRC) (Collaboration)
- University of Copenhagen (Collaboration)
- Leiden University (Collaboration)
- Kobe University (Collaboration)
- Deakin University (Collaboration)
- Newcastle University (Collaboration)
- University Psychiatric Clinics Basel (Collaboration)
- University of Tilburg (Collaboration)
- UNIVERSITY OF CAMBRIDGE (Collaboration)
- Ottawa Hospital Research Institute (Collaboration)
- University of East Anglia (Collaboration)
- Federal University of Maranhão (Collaboration)
- UNIVERSITY OF EXETER (Collaboration)
- Radboud University Nijmegen Medical Center (Collaboration)
- Ipsos MORI (Collaboration)
- University of Bern (Collaboration)
- Central South University (Collaboration)
- Universität Hamburg (Collaboration)
- University of California, San Diego (UCSD) (Collaboration)
- London School of Hygiene and Tropical Medicine (LSHTM) (Collaboration)
- Johnson & Johnson (Collaboration)
- St Thomas' Hospital (Collaboration)
- University of Seville (Collaboration)
- University of Huddersfield (Collaboration)
- University at Albany, State University of New York (Collaboration)
- GENOMICS PLC (Collaboration)
- Federal University of Pelotas (UFPel) (Collaboration)
- University of Otago (Collaboration)
- National Institutes of Health (NIH) (Collaboration)
- KING'S COLLEGE LONDON (Collaboration)
- Government of Canada (Collaboration)
- National Information Processing Institute (Collaboration)
- Nanjing Medical University (Collaboration)
- University of Basel (Collaboration)
- UK Biobank (Collaboration)
- Kingston University London (Collaboration)
- Broad Institute (Collaboration)
- UNIVERSITY OF EDINBURGH (Collaboration)
- QUEEN MARY UNIVERSITY OF LONDON (Collaboration)
- EDGE HILL UNIVERSITY (Collaboration)
- Federal University of Rio de Janeiro (Collaboration)
- UNIVERSITY OF ABERDEEN (Collaboration)
- University of Southern California (Collaboration)
- Chongqing Medical University (CQMU) (Collaboration)
- Pompeu Fabra University (Collaboration)
- Isfahan University of Medical Sciences (Collaboration)
- Florida State University (Collaboration)
- University of Montreal (Collaboration)
- UNIVERSITY OF LEEDS (Collaboration)
- Shengjing Hospital of China Medical University (Collaboration)
- University of Bristol (Collaboration)
- QR8 Health (Collaboration)
- London School of Economics and Political Science (University of London) (Collaboration)
- University of Lausanne (Collaboration)
- UNIVERSITY OF LEICESTER (Collaboration)
- VU University Medical Center (Collaboration)
- Upstate Medical University (Collaboration)
- Xiangya Hospital Central South University (Collaboration)
- University of St Andrews (Collaboration)
- University of Gothenburg (Collaboration)
- University of Virginia (UVa) (Collaboration)
- Center for Research in Environmental Epidemiology (Collaboration)
- Mental Health Services - Capital Region (Collaboration)
- Western General Hospital (Collaboration)
- University of Sussex (Collaboration)
- University of the West of England (Collaboration)
- University of Delaware (Collaboration)
- Teesside University (Collaboration)
- Parliamentary Office of Science and Technology [POST] (Collaboration)
- University of Cincinnati (Collaboration)
- UNIVERSITY OF WATERLOO (Collaboration)
- UNIVERSITY OF KENT (Collaboration)
- University Medical Center Gronigen (Collaboration)
- Bristol Health Partners (Collaboration)
- Mount Sinai Hospital (Canada) (Collaboration)
- Curtin University (Collaboration)
- ASTON UNIVERSITY (Collaboration)
- University of Colorado Boulder (Collaboration)
- Queensland University of Technology (QUT) (Collaboration)
- Ann & Robert H. Lurie Children's Hospital of Chicago (Collaboration)
- Government of the UK (Collaboration)
- The Wellcome Trust Sanger Institute (Collaboration)
- University of Ottawa (Collaboration)
- International Neuroinformatics Coordinating Facility (Collaboration)
- University of Tartu (Collaboration)
- Nemours Children's Clinic (Collaboration)
- University of Geneva (Collaboration)
- DURHAM UNIVERSITY (Collaboration)
- University of Hong Kong (Collaboration)
- East Tennessee State University (Collaboration)
- Ludwig Maximilian University of Munich (LMU Munich) (Collaboration)
- NATIONAL CENTRE FOR SOCIAL RESEARCH (Collaboration)
- University of Canterbury (Collaboration)
- Agency for Science, Technology and Research (A*STAR) (Collaboration)
- Masaryk University (Collaboration)
- Children's Hospital of Fudan University (Collaboration)
- Biogen (Collaboration)
- RTI International (Collaboration)
- PUBLIC HEALTH ENGLAND (Collaboration)
- Buck Institute for Age Research (Collaboration)
- Zhengzhou University (Collaboration)
- University of Galway (Collaboration)
- University of Oulu (Collaboration)
- The University of Texas at San Antonio (Collaboration)
- QUEEN'S UNIVERSITY BELFAST (Collaboration)
- Coventry and Warwickshire Partnership NHS Trust (Collaboration)
- National Center for Scientific Research (Centre National de la Recherche Scientifique CNRS) (Collaboration)
- Dartmouth–Hitchcock Medical Center (Collaboration)
- Chinese Academy of Sciences (Collaboration)
- University of Melbourne (Collaboration)
- University of Rome Tor Vergata (Collaboration)
- Northwestern University (Collaboration)
- Wessex Academic Health Science Network (Collaboration)
- Monash University (Collaboration)
- MRC Dementias Platform UK (Collaboration)
- University of Technology Sydney (Collaboration)
- Fatherhood Institute (Collaboration)
- University of Michigan (Collaboration)
- UK Reproducibility Network (Collaboration)
- We The Curious (Collaboration)
- Centre for Applied Education Research (Collaboration)
- Million Women Study (Collaboration)
- China Agricultural University (CAU) (Collaboration)
- Centre Hospitalier Universitaire Sainte-Justine (Collaboration)
- Nestlé (Global) (Collaboration)
- University of Nebraska at Omaha (Collaboration)
- Bradford Institute for Health Research (BIHR) (Collaboration)
- University of Hasselt (Collaboration)
- Cardiff University (Collaboration)
- Royal College of Surgeons in Ireland (Collaboration)
- UNSW Sydney (Collaboration)
- Universidade de São Paulo (Collaboration)
- Johns Hopkins Medicine (Collaboration)
- UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST (Collaboration)
- University of Manchester (Collaboration)
- UNIVERSITY OF NOTTINGHAM (Collaboration)
- McGill University (Collaboration)
- Peking University (Collaboration)
- South Australian Health and Medical Research Institute (Collaboration)
- Syracuse University (Collaboration)
- Orygen Youth Health (Collaboration)
- Princeton University (Collaboration)
- University of Missouri (Collaboration)
- Weill Cornell Medical College in Qatar (Collaboration)
- Montreal's Jewish General Hospital (Collaboration)
- Bristol Clinical Commissioning Group (Collaboration)
- Adolfo Ibáñez University (Collaboration)
Publications

Abbas H
(2015)
Automatic Classification of Facial Morphology for Medical Applications
in Procedia Computer Science

Abbas H
(2018)
A 3D morphometric perspective for facial gender analysis and classification using geodesic path curvature features
in Computational Visual Media

Abbondanza F
(2024)
A GWAS for grip strength in cohorts of children-Advantages of analysing young participants for this trait.
in Genes, brain, and behavior

Abdulkadir M
(2022)
The impact of anorexia nervosa and BMI polygenic risk on childhood growth: A 20-year longitudinal population-based study
in The American Journal of Human Genetics

Abdulkadir M
(2019)
Polygenic Risk Scores Derived From a Tourette Syndrome Genome-wide Association Study Predict Presence of Tics in the Avon Longitudinal Study of Parents and Children Cohort.
in Biological psychiatry

Abdulkadir M
(2020)
Polygenic Score for Body Mass Index Is Associated with Disordered Eating in a General Population Cohort.
in Journal of clinical medicine

Abdulkadir M
(2022)
Eating disorder symptoms and their associations with anthropometric and psychiatric polygenic scores.
in European eating disorders review : the journal of the Eating Disorders Association

Abdulkadir M
(2023)
Polygenic and environmental determinants of tics in the Avon Longitudinal Study of Parents and Children.
in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics

Abel K
(2019)
Intelligence in offspring born to women exposed to intimate partner violence: a population-based cohort study
in Wellcome Open Research

Abeysekera K
(2022)
Evaluating future risk of NAFLD in adolescents: a prediction and decision curve analysis
in BMC Gastroenterology
Title | Creative Reactions 2018 |
Description | Creative Reactions is an art exhibition associated with the national Pint of Science festival. Approximately 20 researchers using ALSPAC data were paired with local Bristol artists who produced an artwork based upon their research. The exhibition was held from 11-22 May 2018. |
Type Of Art | Artistic/Creative Exhibition |
Year Produced | 2018 |
Impact | Artworks were viewed and seen by the general public as well as the scientific community. Local radio, online and print media covered the exhibition. |
URL | https://pintofscience.co.uk/event/creative-reactions-bristol-launch |
Title | Creative Reactions- Kayleigh Easey |
Description | Collaboration with an artist to produce a piece of artwork that summarises my research on the effects of maternal and paternal drinking in pregnancy on offspring depression. |
Type Of Art | Artwork |
Year Produced | 2018 |
Impact | The artwork is to be displayed in an exhibition in Bristol, involved with Pint of Science. There is to be an opening event that is widely advertised to the public. This work will allow scientists to share with the public their research and the implications it may have. |
URL | https://pintofscience.co.uk/events/bristol |
Title | Data visualisation images on display at We The Curious's Project 'What If' exhibition 2021 |
Description | Researchers using ALSPAC data provided imagery for the Open Science lab at We The Curious, Bristol's science centre. Tom Gaunt, Matthew Lee & others provided images to exhibit and create conversations about data collection in ALSPAC. |
Type Of Art | Artwork |
Year Produced | 2021 |
Impact | Created opportunities for discussion about population health science in a public space. |
URL | https://www.youtube.com/watch?v=TdiOA7Aj3dE |
Title | Researcher videos for social media & website |
Description | A series of video interviews with researchers and collaborators using ALSPAC data. Designed to share the findings and nature of work conducted with a lay audience. |
Type Of Art | Film/Video/Animation |
Year Produced | 2018 |
Impact | Widening awareness of research impact among core audiences - public, participants, collaborators and charities/third parties. It also provides an opportunity for researchers to thank participants and engage them in future participation with the study. |
URL | http://www.bristol.ac.uk/alspac/media/researcher-interviews/ |
Title | Short film on health inequality by Nic Timpson |
Description | Short film with a talking head by Prof Nic Timpson discussing health inequality to accompany an exhibit 'Bristol Health Map' at We The Curious science centre in Bristol |
Type Of Art | Artistic/Creative Exhibition |
Year Produced | 2021 |
Impact | Created an opportunity for discussion around the exhibit Bristol Health Map - showing disparities in health and life expectancies around different wards in Bristol |
URL | https://drive.google.com/file/d/1_lv_RUhos9BxJ3H8qT-gfbycFZdAIH-c/view |
Description | "The one-way mirror: public attitudes to commercial access to health data" |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Description | A longitudinal study of gambling in late adolescence and early adulthood: Follow-up assessment at 24 years |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Impact | This report describes a longitudinal study of young peoples' gambling between 17 and 24 years, using a contemporary UK cohort, the Avon Longitudinal Study of Parents and Children (ALSPAC). The aims of the ALSPAC Gambling Study were to describe gambling behaviour in youth aged 17-24 years, investigate the antecedents of regular and problem gambling, and explore the associations with other addictive behaviours and mental health. |
URL | https://www.begambleaware.org/media/2058/alspac-gambling-study_-report-for-gamble-aware_-july-2019.p... |
Description | ALSPAC Summary for SAGE re: COVID and children/young people |
Geographic Reach | National |
Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
URL | https://hdruk.app.box.com/s/c4p2w3n673js8run56qcbnhtyvjdwyys |
Description | ALSPAC inclusion/reference in the Goldacre review. Exemplar. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Contribution to a national consultation/review |
Impact | Developments around the use of data for health and wellbeing research following the pandemic. |
URL | https://www.goldacrereview.org |
Description | ALSPAC information used in in 'Your Health Record Saves Lives' information booklet produced by UK Clinical Research Collaboration |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | http://www.nhs.uk/Conditions/Clinical-trials/Documents/Research1.pdf |
Description | ALSPAC obesity data cited in government's child obesity strategy |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | https://www.gov.uk/government/publications/childhood-obesity-a-plan-for-action |
Description | ALSPAC research on bullying and maltreatment cited in EHRC race report |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
URL | https://www.equalityhumanrights.com/en/race-report-healing-divided-britain |
Description | ALSPAC research on eczema and genes featured in the National Eczema Society's Exchange magazine (159, March 2016) |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | http://www.eczema.org/products/154 |
Description | ALSPAC research on premature babies quoted in Parliament by Stephen Hammond MP |
Geographic Reach | Local/Municipal/Regional |
Policy Influence Type | Citation in other policy documents |
URL | https://hansard.parliament.uk/commons/2016-10-10/debates/5032D3A8-AA55-4388-BCE2-DE2ACAB8CDCC/School... |
Description | ALSPAC used as example of best practice by Health and Social Care Information Centre |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | http://systems.hscic.gov.uk/infogov/codes/cop |
Description | Adjournment debate on fetal alcohol spectrum disorder |
Geographic Reach | National |
Policy Influence Type | Contribution to a national consultation/review |
URL | https://hansard.parliament.uk/Commons/2019-01-17/debates/19011751000002/FoetalAlcoholSpectrumDisorde... |
Description | Better support is needed for young people vulnerable to abuse in intimate relationships |
Geographic Reach | National |
Policy Influence Type | Influenced training of practitioners or researchers |
Impact | Guidelines for the training of services for young people, healthcare providers and schools |
Description | Bullying research included in textbook |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | The research features in 'Bullying', a textbook in the 'Issues' series by Independence Educational Publishers http://www.independence.co.uk/. It is in a format that is accessible to all levels but is aimed primarily at the 16-18 age group. According to the publisher, the book is used in a wide variety of courses including GCSE, A-level and further education, as well as by public libraries, prison education providers, government agencies and professional health and social care bodies. |
URL | http://www.independence.co.uk/shop/family-and-relationships/issues/bullying |
Description | Bullying research included in textbook |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | The research features in 'Bullying', a textbook in the 'Issues' series by Independence Educational Publishers http://www.independence.co.uk/. It is in a format that is accessible to all levels but is aimed primarily at the 16-18 age group. According to the publisher, the book is used in a wide variety of courses including GCSE, A-level and further education, as well as by public libraries, prison education providers, government agencies and professional health and social care bodies. |
URL | http://www.independence.co.uk/shop/family-and-relationships/issues/bullying |
Description | COVID-19 Health Data Research 04 August 2020 - Weekly update for SAGE & UKRI/DHS |
Geographic Reach | National |
Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
URL | https://www.hdruk.ac.uk/wp-content/uploads/2020/08/200804-Health-Data-Research-UK-COVID-19-fortnight... |
Description | COVID-19 Health Data Research 18 August 2020 - Weekly update for SAGE & UKRI/DHSC |
Geographic Reach | National |
Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
URL | https://www.hdruk.ac.uk/wp-content/uploads/2020/08/200818-Health-Data-Research-UK-COVID-19-fortnight... |
Description | COVID-19 mental health and wellbeing surveillance report (series) |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | https://www.gov.uk/government/publications/covid-19-mental-health-and-wellbeing-surveillance-report/... |
Description | COVID-19 mental health and wellbeing surveillance: report |
Geographic Reach | National |
Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
URL | https://www.gov.uk/government/publications/covid-19-mental-health-and-wellbeing-surveillance-report |
Description | COVID-19 response |
Geographic Reach | National |
Policy Influence Type | Participation in a guidance/advisory committee |
Impact | Understanding of a broad range of health related factors surrounding the impact of the pandemic. From COVID-19 itself to lockdown. |
URL | http://www.ucl.ac.uk/covid-19-longitudinal-health-wellbeing/research-outputs |
Description | Change in Information Commissioner's Office code of practice guidance on data protection following the Data Protection Act 2018 |
Geographic Reach | National |
Policy Influence Type | Participation in a guidance/advisory committee |
Impact | CLOSER work on the need for clearer and changed regulatory guidance regarding data retention (see Boyd et al. 2018, available from: https://wellcomeopenresearch.org/articles/3-112/v1) led to a change in official guidance from the Information Commissioner's Office (see https://ico.org.uk/for-organisations/guide-to-data-protection/guide-to-the-general-data-protection-regulation-gdpr/principles/storage-limitation/). This has the potential to help safeguard data which could be used as research resources of the future. |
URL | https://ico.org.uk/for-organisations/guide-to-data-protection/guide-to-the-general-data-protection-r... |
Description | Chapter on childhood asthma included in RCPCH air pollution report |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | https://www.rcplondon.ac.uk/projects/outputs/every-breath-we-take-lifelong-impact-air-pollution |
Description | Children who fail to meet UK dietary guidelines have worse cardiometabolic health as young adults |
Geographic Reach | National |
Policy Influence Type | Influenced training of practitioners or researchers |
Impact | This research comes as the UK government develops its Major Conditions Strategy, designed to improve the health of the nation, including prevention of heart disease. Our results can help inform future policies in this area and strategies to reduce emergence of CVD risk factors early in life. |
URL | https://www.gov.uk/government/publications/the-eatwell-guide |
Description | Cohorts knowledge panel - CIHR & Genomes Canada |
Geographic Reach | North America |
Policy Influence Type | Membership of a guideline committee |
Description | Department for Education on grandparental care during COVID-19 pandemic and mitigation. |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | https://www.gov.uk/government/publications/quick-findings-on-age-distributions-of-grandparents-and-p... |
Description | Eating disorder symptoms and self-harm are linked to higher levels of depression and anxiety during the COVID-19 pandemic |
Geographic Reach | National |
Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
URL | https://www.bristol.ac.uk/media-library/sites/policybristol/briefings-and-reports-pdfs/2021/PolicyBr... |
Description | Evidence included in Commons Health Select Committee report |
Geographic Reach | National |
Policy Influence Type | Contribution to a national consultation/review |
URL | http://www.publications.parliament.uk/pa/cm201415/cmselect/cmhealth/845/845.pdf |
Description | Evidence that little time outdoors contributes to the development of myopia in middle childhood |
Geographic Reach | National |
Policy Influence Type | Citation in clinical reviews |
Description | Findings of research on dyslexia and vision recommended by Dyslexia Action |
Geographic Reach | National |
Policy Influence Type | Influenced training of practitioners or researchers |
URL | http://www.dyslexiaaction.org.uk/news/%E2%80%98dyslexia-and-sight-wider-view%E2%80%99-research-welco... |
Description | Guidance on iodine cited by Scientific Advisory Committee on Nutrition |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | https://www.gov.uk/government/publications/sacn-statement-on-iodine-and-health-2014 |
Description | HDRUK - Lessons from COVID-19: How can we put the UK at the forefront of health data science? |
Geographic Reach | National |
Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
URL | https://www.hdruk.ac.uk/wp-content/uploads/2020/07/Lessons-from-COVID-19-for-UK-Health-Data-Science.... |
Description | HDRUK - regular updates for SAGE, National Core Studies & UKRI/DHSC (ALSPAC have contribute to 7 of these) |
Geographic Reach | National |
Policy Influence Type | Participation in a guidance/advisory committee |
URL | https://www.hdruk.ac.uk/wp-content/uploads/2021/02/2021-02-23-Health-Data-Research-UK-SAGE-report.pd... |
Description | Health Data Research UK Infrastructure Advisory Group |
Geographic Reach | National |
Policy Influence Type | Membership of a guideline committee |
URL | https://www.hdruk.ac.uk/about-us/who-we-are/our-advisory-groups/ |
Description | Impact of voluntary risk-mitigation behaviour on the magnitude of a COVID-19 Omicron variant wave in England, 11 January 2022 |
Geographic Reach | National |
Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
URL | http://www.gov.uk/government/publications/university-of-bristol-impact-of-voluntary-risk-mitigation-... |
Description | Internet use and suicide |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Contribution to a national consultation/review |
Impact | Work has highlighted the importance of internet use for understanding the architecture of suicidal behaviour. It has been specifically supported by a Department of Health Policy Research Programme and an ESRC Impact Accelerator Account and has already fed into the All Party Parliamentary Group (APPG) on suicide, the APPG on Social Media and Young People's Mental Health, a report by the House of Commons Health Select Committee on Suicide Prevention https://publications.parliament.uk/pa/cm201617/cmselect/cmhealth/1087/1087.pdf, a Royal College of Psychiatrist Patient Safety report and reviews of industry practice (e.g. advising YouTube). |
Description | Internet use and suicide |
Geographic Reach | Europe |
Policy Influence Type | Participation in a guidance/advisory committee |
Impact | Description and advice with respect to the improvement of understanding of relationships between online content and mental health/self-harm/suicide. |
Description | Internet use and the impact of this on mental health and well-being |
Geographic Reach | National |
Policy Influence Type | Contribution to a national consultation/review |
Description | Involvement of ALSPAC in the formation of Joint Strategic Needs Assessment - Chlamydia prevalence |
Geographic Reach | Local/Municipal/Regional |
Policy Influence Type | Citation in other policy documents |
Guideline Title | European Association for the Study of the Liver guidelines on use of non-invasive tests. |
Description | Liver health and disease |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in clinical guidelines |
Impact | Guidelines on testing and implementing measures to improve liver health. |
Description | Maternal depression increases generation on generation. |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Impact | Pearson RM, et al. Prevalence of Prenatal Depression Symptoms Among 2 Generations of Pregnant Mothers. JAMA Network Open 2018, 1:e180725 KEY IMPACT - The findings have had global media attention including live tv and radio and the results have been commented on by the Royal College of Midwives and the Maternal Mental Health Alliance. The work is new and has not yet delivered measurable policy change, but highlights the need for increased support for young pregnant women in the current enviro-socio-economic climate. The research has already supported national campaigns to facilitate universal screening for depression (and anxiety) by midwives, for the prioritisation of pregnant women for free psychological therapies and for provision of specialist perinatal mental health community mental health teams across the UK. |
Description | Maternal iodine status and child early and later life health outcomes. |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Description | Maternal iodine status and child early and later life health outcomes. |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Description | Maternal iodine status and early child health outcomes. |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Description | Maternal iodine status and health of the child |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Description | Maternal iodine status in early pregnancy |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Impact | Sarah Bath - University of Surrey- able to look back in time to maternal iodine status in early pregnancy so that we could explore the relationship with child cognition. Using ALSPAC was cost-effective as cognitive measures were available in the child, and samples were available from the mother which we could use for the measurement of maternal iodine status. ALSPAC, unlike many other biobanks had urine samples from very early in pregnancy - which was the time that we were interested in. Iodine and thyroid hormones are required from conception and during the first half of pregnancy the mother is the sole source of thyroid hormone and so adequate iodine is critical; we therefore wanted to measure iodine status as early as possible. ALSPAC also had dietary information, via the food frequency questionnaire completed in pregnancy, which we have been able to use in our follow-on project (EUthyroid - a Horizon 2020 project). Published our research paper in the Lancet in May 2013. Work cited as an example in Medical Research Council document "Outputs, outcomes and impact of MRC research: 2013/14 report". Publication of a fact sheet on iodine for the general public/health practitioners via the British Dietetic Association. Iodine now included in fact sheets for pregnant women by the Infant and Toddler Forum. Work cited in Dairy Council's new publication on iodine. Work cited in iodine review by the Scientific Advisory Committee on Nutrition (gov). Work cited by EFSA in document on Dietary Reference Value for iodine: European Food Safety Authority (2014) Scientific Opinion on Dietary Reference Values for iodine. EFSA Journal 12, 3660. Paper featured in NICE "Eyes on Evidence" February 2014. Further grant funding for follow-on project: European Commission Horizon 2020 EUthyroid: towards the elimination of iodine deficiency and preventable thyroid-related diseases in Europe. Grant agreement No 634453 |
Description | Maternal iodine status in early pregnancy and child health |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Description | Maternal iodine status in early pregnancy and child health (2014) |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Description | Maternal iodine status in early pregnancy and child health (2014) (2014) |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Description | New evidence on vitamin D supplementation in pregnancy from research showing that vitamin D status in pregnancy not associated with offspring bone mineral content |
Geographic Reach | National |
Policy Influence Type | Citation in clinical reviews |
Description | New guidance on alcohol in pregnancy endorsed by Dr Simon Newell (RCOP), James Nicholls (Alcohol Research UK) and Professor David Nutt, Imperial. |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
Description | New guidance on importance of iodine in pregnancy diet backed up by BDA factsheet http://www.bda.uk.com/foodfacts/Iodine.pdf |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | https://www.bda.uk.com/foodfacts/Iodine |
Description | Our Future Health Scientific Advisory Board |
Geographic Reach | National |
Policy Influence Type | Membership of a guideline committee |
URL | https://ourfuturehealth.org.uk |
Description | PHE Mental health - Research and analysis 7. Age Spotlight Updated 18 November 2021 |
Geographic Reach | National |
Policy Influence Type | Implementation circular/rapid advice/letter to e.g. Ministry of Health |
URL | https://www.gov.uk/government/publications/covid-19-mental-health-and-wellbeing-surveillance-spotlig... |
Description | Paediatric incontinence: early identification and treatment needed to prevent mental health problems |
Geographic Reach | National |
Policy Influence Type | Influenced training of practitioners or researchers |
Impact | Clinicians need to know that incontinence has a negative impact on mental health, especially if it persists into later childhood and adolescence. Mental health and/or psychological support should be routinely available in paediatric bladder and bowel clinics but is currently lacking due to resource constraints. Parents and carers should be taught what is typical for their child's bladder and bowel health and acquisition of continence. Parents and carers should be encouraged to seek early assessment and intervention for any new or existing childhood incontinence or bladder/bowel issue. Parents, carers, and clinicians should be aware that constipation is often an underlying cause of childhood incontinence and should always be proactively treated as soon as it is recognised. Parents, carers, and clinicians need to know that many children do not simply grow out of incontinence and that problems often become more difficult to treat with increasing age. |
Description | Participation in All Party Parliamentary Group on Autism - building brighter futures for children with autism event (10 July 2018) |
Geographic Reach | National |
Policy Influence Type | Participation in a guidance/advisory committee |
Description | Policy Bristol - briefings |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Citation in other policy documents |
URL | https://www.bristol.ac.uk/policybristol/policy-briefings/young-adult-relationships/ |
Description | Questionnaire, linkage and interview data inform BIS report |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | https://www.gov.uk/government/publications/progression-into-higher-education-for-disadvantaged-and-u... |
Description | Quick findings on age distributions of grandparents and parents of primary school aged children - .gov (asset - Centre for Ageing and Demography) |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/8934... |
Description | Research on school outcomes for premature babies endorsed by Professor Sir Al Aynsley Green (first Children's Commissioner for England) |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
Description | Short Report on Long COVID - Office for National Statistics |
Geographic Reach | National |
Policy Influence Type | Citation in other policy documents |
URL | https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1007... |
Description | Submitted evidence to Commons Health Select committee inquiry into suicide prevention |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Contribution to a national consultation/review |
URL | http://data.parliament.uk/WrittenEvidence/CommitteeEvidence.svc/EvidenceDocument/Health/Suicide%20Pr... |
Description | Submitted evidence to Commons Health Select committee inquiry into suicide prevention |
Geographic Reach | Multiple continents/international |
Policy Influence Type | Contribution to a national consultation/review |
URL | http://data.parliament.uk/WrittenEvidence/CommitteeEvidence.svc/EvidenceDocument/Health/Suicide%20Pr... |
Description | Where's the daddy? Fathers and father-figures in UK datasets - The Fatherhood Institute |
Geographic Reach | National |
Policy Influence Type | Citation in systematic reviews |
Impact | Review aims - Firstly, for funders and providers of large-scale quantitative datasets, a documentation of questions and fieldwork practices which enable researchers to identify specific categories of fathers and collect data directly from fathers. Secondly, for researchers planning secondary analyses to study fathers, an assessment of whether different categories of fathers can be identified in the data. ALSPAC forms a key part of the evidence contained within this review. |
Description | "Improving Understanding Of Weight Stigma With Causal Inference Methods And General Population Survey Data". |
Amount | £242,921 (GBP) |
Funding ID | ES/X000486/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 03/2023 |
End | 03/2025 |
Description | (LONGITOOLS) - Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases |
Amount | € 11,997,449 (EUR) |
Funding ID | 874739 |
Organisation | European Commission |
Sector | Public |
Country | European Union (EU) |
Start | 01/2020 |
End | 12/2024 |
Description | 2020 Special Research Awards: Covid-19 scheme |
Amount | £8,669 (GBP) |
Funding ID | COV19\200057 |
Organisation | The British Academy |
Sector | Academic/University |
Country | United Kingdom |
Start | 07/2020 |
End | 07/2023 |
Description | 37356: Scourfield fellowship: Fathers, social interventions and children's wellbeing |
Amount | £8,482 (GBP) |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 08/2011 |
End | 08/2014 |
Description | 38361: The determinants of measures of immune function in a wild mammal. |
Amount | £5,000 (GBP) |
Organisation | Natural Environment Research Council |
Sector | Public |
Country | United Kingdom |
Start | 06/2011 |
End | 01/2015 |
Description | 43249: NICE childhood obesity weight management |
Amount | £2,250 (GBP) |
Funding ID | F00003186 |
Organisation | National Institute for Health and Care Excellence (NICE) |
Sector | Public |
Country | United Kingdom |
Start | 03/2012 |
End | 03/2014 |
Description | 43992: POPPIE Predictors of Persistence & Psychological Impact of Childhood Eczema |
Amount | £800 (GBP) |
Funding ID | F00022685 |
Organisation | National Institute for Health Research |
Sector | Public |
Country | United Kingdom |
Start | 05/2012 |
End | 11/2012 |
Description | 47297: B1227 Biomarker study |
Amount | £2,593 (GBP) |
Organisation | Royal College of Surgeons in Ireland |
Sector | Academic/University |
Country | Ireland |
Start | 03/2013 |
End | 02/2017 |
Description | 59452: C.Williams Senior Research Fellowship |
Amount | £37,043 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 09/2015 |
End | 09/2020 |
Description | A Recall by Genotype Study to investigate the role of common TRPA1 variants on acute pain perception |
Amount | £39,813 (GBP) |
Funding ID | ABL-2019-20-10 |
Organisation | University Hospitals Bristol NHS Foundation Trust |
Sector | Hospitals |
Country | United Kingdom |
Start | 12/2019 |
End | 11/2021 |
Description | A Recall by Genotype Study to investigate the role of common TRPA1 variants on acute pain perception |
Amount | £39,813 (GBP) |
Organisation | University Hospitals Bristol NHS Foundation Trust |
Department | Above and Beyond Grants |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 01/2019 |
End | 11/2021 |
Description | A UK underpinning platform to study immunology and immunopathology of COVID-19:The UK Coronavirus Immunology Consortium |
Amount | £6,552,119 (GBP) |
Funding ID | MR/V028448/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 07/2020 |
End | 08/2022 |
Description | A framework for linking and sharing social media data for high-resolution longitudinal measurement of mental health across CLOSER cohorts |
Amount | £149,971 (GBP) |
Funding ID | ES/R011583/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 03/2018 |
End | 02/2019 |
Description | A life course approach to understanding ADHD among women |
Amount | £768,160 (GBP) |
Funding ID | MR/X02220X/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 07/2023 |
End | 07/2026 |
Description | ALSPAC Additional Funding from 01/04/2019 to 31/07/2019 |
Amount | £283,265 (GBP) |
Funding ID | 102215/Z/13/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2019 |
End | 07/2019 |
Description | ALSPAC CRN Funding 22/23 |
Amount | £96,541 (GBP) |
Funding ID | UoB-ALSPAC22/23 |
Organisation | UK Clinical Research Network (UKCRN) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2022 |
End | 03/2023 |
Description | ALSPAC Questionnaire - dietary preference |
Amount | £10,000 (GBP) |
Organisation | University of Edinburgh |
Sector | Academic/University |
Country | United Kingdom |
Start | 05/2017 |
End | 12/2017 |
Description | Accumulative processes in health inequalities: the socioeconomic causes and consequences of mental and physical health comorbidity in adolescence |
Amount | £229,631 (GBP) |
Funding ID | ES/T013923/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 11/2020 |
End | 01/2023 |
Description | Addressing the adverse impacts of domestic violence during pregnancy |
Amount | £129,956 (GBP) |
Funding ID | WF19\190262 |
Organisation | The British Academy |
Sector | Academic/University |
Country | United Kingdom |
Start | 03/2022 |
End | 04/2025 |
Description | Adolescent and adult mental health outcomes of autism and autistic traits |
Amount | £226,152 (GBP) |
Funding ID | MR/R004889/1 |
Organisation | Medical Research Council (MRC) |
Department | Medical Research Foundation |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 05/2017 |
End | 05/2019 |
Description | Adolescent and adult mental health outcomes of autism and autistic traits |
Amount | £74,096 (GBP) |
Funding ID | TRUST/VC/AC/SG/3747-6849 |
Organisation | Baily Thomas Charitable Fund |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 02/2016 |
End | 03/2018 |
Description | Adult peak circulatory capacity in the Avon Longitudinal Study of Parents and Children (ALSPAC): mechanisms and exposures (ACME) |
Amount | £441,633 (GBP) |
Funding ID | SP/F/21/150020 |
Organisation | British Heart Foundation (BHF) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 11/2021 |
End | 06/2024 |
Description | Adverse life events, inflammation, and trajectories of emotional and behavioural problems in childhood |
Amount | £161,295 (GBP) |
Funding ID | ES/P001742/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 03/2017 |
End | 05/2018 |
Description | Alzheimer's Research UK Research Fellowship |
Amount | £263,088 (GBP) |
Funding ID | ARUK-RF2021B-006 |
Organisation | Alzheimer's Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2022 |
End | 03/2025 |
Description | An investigation of the causal pathways from childhood conduct problems to poor health outcomes and criminal behaviour in adulthood |
Amount | £250,000 (GBP) |
Funding ID | 209138/Z/17/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2018 |
End | 03/2022 |
Description | Anxiety and depression in young people: who do they affect, who seeks treatment, and who responds to treatment? |
Amount | £40,000 (GBP) |
Funding ID | 226694/Z/22/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 07/2022 |
End | 03/2023 |
Description | Anxiety and depression in young people: who do they affect, who seeks treatment, and who responds to treatment? |
Amount | £40,000 (GBP) |
Funding ID | 226694/Z/22/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 07/2022 |
End | 03/2023 |
Description | Applying causal inference methods to investigate the impact of adverse childhood experiences on mental health |
Amount | £300,000 (GBP) |
Funding ID | 215917/Z/19/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 11/2019 |
End | 06/2024 |
Description | Are sleep difficulties in ADHD an index of neurodevelopmental severity? |
Amount | £57,539 (GBP) |
Funding ID | 918-3021 |
Organisation | The Waterloo Foundation |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2017 |
End | 10/2020 |
Description | Autism Speaks B954 RX9194 'Genetic Variation and Gene-Environment Influences in Autistic-like traits' |
Amount | £71,704 (GBP) |
Funding ID | 7132 |
Organisation | Autism Speaks |
Sector | Charity/Non Profit |
Country | United States |
Start | 12/2011 |
End | 05/2014 |
Description | B2390 Internal Locus of Control: Origins, Determinants, and Benefits |
Amount | £5,000 (GBP) |
Funding ID | 58223 |
Organisation | The John Templeton Foundation |
Sector | Academic/University |
Country | United States |
Start | 08/2015 |
Description | BIOSHARE Social Core - Qualatative Study |
Amount | £1,806 (GBP) |
Funding ID | Health-F4-2010-261433 |
Organisation | European Commission |
Sector | Public |
Country | European Union (EU) |
Start | 06/2014 |
End | 01/2015 |
Description | Behavioural and neurophysiological effects of schizophrenia risk genes |
Amount | £789,477 (GBP) |
Funding ID | MR/K004360/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start |
Description | Biomarkers in Atopic Dermatitis and Psoriasis (BIOMAP) |
Amount | € 10,499,999 (EUR) |
Funding ID | 821511 |
Organisation | European Commission H2020 |
Sector | Public |
Country | Belgium |
Start | 03/2019 |
End | 03/2024 |
Description | Biomarkers to investigate Genetics, Environment and Mechanisms in Schizophrenia (Bio-GEMS). |
Amount | £1,016,445 (GBP) |
Funding ID | MR/W020238/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2022 |
End | 12/2025 |
Description | Biomedical Research Centre (BRC) in Cardiovascular disease, mental health, nutrition, diet and lifestyle (including obesity), reproductive and perinatal health, surgical innovation. |
Amount | £20,000,000 (GBP) |
Organisation | National Institute for Health Research |
Sector | Public |
Country | United Kingdom |
Start | 03/2017 |
End | 04/2022 |
Description | British Heart Foundation funded PhD programme in cardiovascular science. Interdisciplinary PhD studentship programme in integrative cardiovascular science. 5 students per year for 4 years. |
Amount | £2,500,000 (GBP) |
Organisation | British Heart Foundation (BHF) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2017 |
End | 10/2021 |
Description | CLOSER (21/22 Extension) |
Amount | £55,000 (GBP) |
Funding ID | ES/K000357/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 03/2021 |
End | 03/2022 |
Description | CLOSER AMENDMENT 4: CLOSER INNOVATION FUND |
Amount | £112,678 (GBP) |
Organisation | Economic and Social Research Council |
Department | ESRC Seminar Series |
Sector | Academic/University |
Country | United Kingdom |
Start | |
End | 09/2017 |
Description | CLOSER Amendment 1: Cohort and Longitudinal Studies Enhancement Resources Grant |
Amount | £327,143 (GBP) |
Organisation | Economic and Social Research Council |
Department | ESRC Seminar Series |
Sector | Academic/University |
Country | United Kingdom |
Start | |
End | 09/2019 |
Description | CLOSER Amendment 3: Cohort and longitudinal studies enhancement resources grant |
Amount | £149,136 (GBP) |
Organisation | Economic and Social Research Council |
Department | ESRC Seminar Series |
Sector | Academic/University |
Country | United Kingdom |
Start | |
End | 09/2019 |
Description | CLOSER Amendment 5: Innovation Fund - Occupational and social class data coding and harmonisation |
Amount | £9,811 (GBP) |
Funding ID | ES/K000357/1 |
Organisation | Economic and Social Research Council |
Department | ESRC Seminar Series |
Sector | Academic/University |
Country | United Kingdom |
Start | 01/2016 |
End | 08/2017 |
Description | CLOSER Ammendment 2: Cohort and longitudinal studies enhancement resources |
Amount | £95,684 (GBP) |
Organisation | Economic and Social Research Council |
Department | ESRC Seminar Series |
Sector | Academic/University |
Country | United Kingdom |
Start | |
End | 09/2017 |
Description | COVID-19 Longitudinal Health and Wellbeing - National Core Study (LWH-NCS) |
Amount | £9,862,000 (GBP) |
Funding ID | MC_PC_20030 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 09/2020 |
End | 03/2021 |
Description | COVID-19 Questionnaire support |
Amount | £6,598 (GBP) |
Organisation | University of Bristol |
Sector | Academic/University |
Country | United Kingdom |
Start | 03/2020 |
End | 07/2020 |
Description | CRN West of England 19/20 ALSPAC Funding |
Amount | £27,994 (GBP) |
Organisation | UK Clinical Research Network (UKCRN) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2019 |
End | 03/2020 |
Description | CRN West of England 20/21 ALSPAC Funding |
Amount | £96,788 (GBP) |
Organisation | UK Clinical Research Network (UKCRN) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2020 |
End | 03/2021 |
Description | CRN West of England 21/22 ALSPAC Funding |
Amount | £96,541 (GBP) |
Organisation | UK Clinical Research Network (UKCRN) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2021 |
End | 03/2022 |
Description | CRN West of England 23/24 ALSPAC Funding |
Amount | £98,406 (GBP) |
Funding ID | UoB-ALSPAC23/24 |
Organisation | UK Clinical Research Network (UKCRN) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2023 |
End | 03/2024 |
Description | Can Hip DXA scans be used to identify genetic determinants of hip shape & osteoarthritis? Proposal for a proof-of-concept study B1372 |
Amount | £11,429 (GBP) |
Funding ID | 20244 |
Organisation | Versus Arthritis |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 02/2013 |
End | 01/2016 |
Description | Cardiac and vascular disease prevention after hypertensive pregnancy: insights from AI-derived, multi-organ, hypertensive disease progression models |
Amount | £1,981,099 (GBP) |
Funding ID | MR/W003686/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 02/2022 |
End | 01/2027 |
Description | Characterising brain network differences during scene perception and memory in young adult APOE-e4 carriers: multi-modal imaging in ALSPAC |
Amount | £1,420,574 (GBP) |
Funding ID | MR/N01233X/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 09/2016 |
End | 04/2020 |
Description | Childhood adversity, DNA methylation, and risk for depression: A longitudinal study of protective factors and sensitive periods in development |
Amount | $879,480 (USD) |
Funding ID | 1R01MH130442-01A1 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 04/2023 |
End | 02/2024 |
Description | Childhood predictors of inadequate health literacy in young adults |
Amount | £28,568 (GBP) |
Organisation | Sir Halley Stewart Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2017 |
End | 02/2019 |
Description | Clinical Research Training Fellowship (Simon Haworth) |
Amount | £167,384 (GBP) |
Funding ID | 201268/Z/16/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 04/2016 |
End | 05/2019 |
Description | Clinical and Genetic Characterization of hEDS using Big Data Analysis |
Amount | £12,000 (GBP) |
Funding ID | Project 1257506 |
Organisation | Ehlers-Danlos Society |
Sector | Charity/Non Profit |
Country | United States |
Start | 05/2019 |
End | 05/2020 |
Description | Cohorts as Platforms for Mental Health research (CaP:MH) |
Amount | £1,497,192 (GBP) |
Funding ID | MC_PC_17210 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2018 |
End | 03/2022 |
Description | Cohorts as Platforms for Mental Health research (MRC MH Pathfinder) |
Amount | £1,497,192 (GBP) |
Funding ID | MC_PC_17210 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2018 |
End | 03/2020 |
Description | Computational Models for the Prediction and Prevention of Child Traumatic Stress |
Amount | $781,926 (USD) |
Funding ID | 1R01MH119114-01A1 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 08/2019 |
End | 05/2023 |
Description | Consortium Against Pain inEquality (CAPE) - The impact of adverse childhood experiences on chronic pain and responses to treatment |
Amount | £2,988,176 (GBP) |
Funding ID | MR/W002566/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 06/2021 |
End | 06/2025 |
Description | Consortium on Vulnerability to Externalizing Disorders and Addictions (c-VEDA) |
Amount | £1,190,293 (GBP) |
Funding ID | MR/N000390/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 09/2015 |
End | 09/2018 |
Description | Consortium to Research Individual, Interpersonal, and Social influences in Pain (CRIISP) |
Amount | £3,824,159 (GBP) |
Funding ID | MR/W004151/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 06/2021 |
End | 06/2025 |
Description | Creating a West African BioResource for Nutritional Genetics and Epigenetics |
Amount | £186,171 (GBP) |
Funding ID | MC_PC_MR/R020183/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2018 |
End | 02/2019 |
Description | Creating a West African BioResource for Nutritional Genetics and Epigenetics |
Amount | £186,171 (GBP) |
Funding ID | MC_PC_MR/R020183/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 01/2018 |
End | 12/2018 |
Description | Cytoprotective defence mechanisms during tissue maintenance and repair - Helen Weaver |
Amount | £1,159,829 (GBP) |
Funding ID | 208762/Z/17/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 06/2018 |
End | 07/2023 |
Description | Defining 'clinically actionable' genetic mechanisms in atopic eczema risk and resolution |
Amount | £2,258,810 (GBP) |
Funding ID | 220875/Z/20/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 11/2020 |
End | 10/2025 |
Description | Deriving and validating a clinical prediction rule for the diagnosis of asthma in primary care |
Amount | £207,554 (GBP) |
Funding ID | CAF/17/01 |
Organisation | Chief Scientist Office |
Sector | Public |
Country | United Kingdom |
Start | 08/2017 |
End | 06/2021 |
Description | Describing habitual levels of physical activity (PA) in older people in terms of impact loads and how this relates to bone and other systems |
Amount | £58,433 (GBP) |
Funding ID | MR/K024973/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 06/2013 |
End | 06/2016 |
Description | Development and evaluation of a pathway from 'universal screening' to online intervention for children with anxiety problems |
Amount | £252,066 (GBP) |
Funding ID | RP-PG-0218-20010 |
Organisation | National Institute for Health Research |
Sector | Public |
Country | United Kingdom |
Start | 06/2019 |
End | 06/2025 |
Description | Development of ALSPAC Industry Partner and Participant Portal |
Amount | £15,000 (GBP) |
Organisation | University of Bristol |
Sector | Academic/University |
Country | United Kingdom |
Start | 03/2018 |
End | 08/2018 |
Description | Development of ALSPAC Industry Partner and Participant Portal (Timpson NJ, Skinner A.) |
Amount | £15,000 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 04/2018 |
End | 05/2019 |
Description | Diagnoptics - AGE readers for field use (Recall by Genotype) in the MRC IEU |
Amount | £50,000 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 02/2017 |
End | 05/2017 |
Description | Discovery science to map the common genetic architecture of fine and gross infant motor development in the context of neurodevelopment and autism |
Amount | $299,486 (USD) |
Funding ID | 724306 |
Organisation | Simons Foundation |
Sector | Charity/Non Profit |
Country | United States |
Start | 03/2021 |
End | 02/2023 |
Description | Discovery science to map the common genetic architecture of fine and gross infant motor development in the context of neurodevelopment and autism |
Amount | $299,486 (USD) |
Funding ID | 724306 |
Organisation | Simons Foundation |
Sector | Charity/Non Profit |
Country | United States |
Start | 03/2021 |
End | 02/2023 |
Description | Do epigenetic markers contribute to the excess risk of diabetes and coronary heart disease in Indian Asians? |
Amount | £196,086 (GBP) |
Funding ID | 082464/Z/07/C |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start |
Description | Does epigenetic methylation explain the gender-switch in adolescent asthma? |
Amount | $153,747 (USD) |
Funding ID | 1R01A/121226-01 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 01/2016 |
End | 12/2016 |
Description | Driven exercise and risk for eating disorders: A combined genetic and longitudinal epidemiological investigation |
Amount | $185,712 (USD) |
Funding ID | 1K01MH123914-01 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 05/2020 |
End | 05/2024 |
Description | Driven exercise and risk for eating disorders: A combined genetic and longitudinal epidemiological investigation |
Amount | $742,848 (USD) |
Funding ID | 1K01MH123914-01 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 05/2020 |
End | 05/2024 |
Description | Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases |
Amount | £8,327,295 (GBP) |
Organisation | European Commission H2020 |
Sector | Public |
Country | Belgium |
Start | 07/2019 |
End | 07/2024 |
Description | Dynamic longitudinal exposome trajectories in cardiovascular and metabolic non-communicable diseases (LONGITOOLS) |
Amount | € 11,997,449 (EUR) |
Funding ID | 874739 |
Organisation | European Research Council (ERC) |
Sector | Public |
Country | Belgium |
Start | 01/2020 |
End | 12/2024 |
Description | EXposome Powered tools for healthy living in urbAN SEttings |
Amount | € 11,993,907 (EUR) |
Funding ID | 874627 |
Organisation | European Commission |
Sector | Public |
Country | European Union (EU) |
Start | 01/2020 |
End | 12/2024 |
Description | Early adulthood education/employment transitions and the development of inequalities in diet quality and cardiovascular health |
Amount | £1,096,469 (GBP) |
Funding ID | MR/T010576/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2020 |
End | 03/2025 |
Description | Early life adversity and life course health: an investigation of adversity clustering and associations with health |
Amount | £232,283 (GBP) |
Funding ID | ES/P010229/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 01/2018 |
End | 12/2020 |
Description | Early life adversity: trajectories to mental health and drug use |
Amount | $60,000 (AUD) |
Funding ID | 19/10685105 |
Organisation | Channel 7 Children's Research Foundation |
Sector | Charity/Non Profit |
Country | Australia |
Start | 03/2019 |
End | 02/2021 |
Description | Eating Behaviour Measurement using the Mandometer - A Pilot Study In ALSPAC B1038 |
Amount | £600 (GBP) |
Organisation | National Institute for Health Research |
Department | NIHR Biomedical Research Centre |
Sector | Public |
Country | United Kingdom |
Start | 01/2012 |
End | 12/2012 |
Description | Effect of different feeding methods and non-nutritive sucking behaviours on child speech development |
Amount | £52,438 (GBP) |
Funding ID | ICA-CDRF-2016-02-053 |
Organisation | National Institute for Health Research |
Sector | Public |
Country | United Kingdom |
Start | 03/2017 |
End | 03/2021 |
Description | Efficient and transparent methods for linking and analysing longitudinal population studies and administrative data |
Amount | £301,055 (GBP) |
Funding ID | 212953/Z/18/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 04/2019 |
End | 12/2025 |
Description | Electronic Longitudinal Alcohol Study in Communities (ELAStiC) |
Amount | £978,102 (GBP) |
Funding ID | ES/L015471/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 09/2016 |
End | 09/2019 |
Description | Elizabeth Blackwell Institute Extension Fellowship (Leila Thuma) |
Amount | £46,467 (GBP) |
Organisation | University of Bristol |
Department | Elizabeth Blackwell Institute for Health Research |
Sector | Academic/University |
Country | United Kingdom |
Start | 11/2016 |
End | 08/2017 |
Description | Elizabeth Blackwell Institute Postgraduate Extension Scheme (Michelle Taylor) |
Amount | £32,817 (GBP) |
Organisation | University of Bristol |
Department | Elizabeth Blackwell Institute for Health Research |
Sector | Academic/University |
Country | United Kingdom |
Start | 09/2016 |
End | 06/2017 |
Description | Emotional dysregulation, self-harm and eating disorders: a mechanistic investigation |
Amount | £251,713 (GBP) |
Funding ID | MR/S020292/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 08/2019 |
End | 09/2022 |
Description | Enhancing Environmental data Resources in Cohort Studies: ALSPAC exemplar (ERICA) |
Amount | £99,899 (GBP) |
Funding ID | NE/P010830/1 |
Organisation | Natural Environment Research Council |
Sector | Public |
Country | United Kingdom |
Start | 02/2017 |
End | 01/2018 |
Description | Environmental risk factors of health-risk behaviours: Using DNA to strenghten causal inference |
Amount | £225,000 (GBP) |
Organisation | MQ Mental Health Research |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 01/2017 |
End | 01/2020 |
Description | Epidemiological studies of human transgenerational responses (TGR) to paternal and ancestral exposures |
Amount | $25,000 (USD) |
Funding ID | 2016-165617 |
Organisation | Silicon Valley Community Foundation |
Sector | Charity/Non Profit |
Country | United States |
Start | 01/2017 |
End | 12/2017 |
Description | Epigenetic predictors of time-varying exposures to childhood adversity and depression |
Amount | $224,448 (USD) |
Funding ID | R21MH132947-01 |
Organisation | Department of Health and Human Services |
Sector | Public |
Country | United States |
Start | 02/2023 |
End | 01/2024 |
Description | Ethical aspects of epidemiological research on young people involving linkage to routine individual data B1089 |
Amount | £860 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 01/2012 |
End | 10/2012 |
Description | Excessive drinking and alcohol related harms in Adulthood: ALSPAC at 24 |
Amount | £1,378,535 (GBP) |
Funding ID | MR/L022206/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 05/2015 |
End | 05/2019 |
Description | Exome Sequencing of ALSPAC, Born in Bradford and Fenland Cohorts |
Amount | £3,000,000 (GBP) |
Funding ID | MC PC 23015 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2023 |
End | 09/2025 |
Description | Exploiting genomic approaches to identify the environmental basis of depression |
Amount | £2,530,384 (GBP) |
Funding ID | 220857/Z/20/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 05/2021 |
End | 05/2026 |
Description | Exploring the role of early-life vascular risk factors linking heart and brain health |
Amount | £263,088 (GBP) |
Funding ID | ARUK-RF2021B-006 |
Organisation | Alzheimer's Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2022 |
End | 03/2025 |
Description | Extraordinary COVID-19 questionnaire |
Amount | £5,650 (GBP) |
Organisation | University of Bristol |
Department | Elizabeth Blackwell Institute for Health Research |
Sector | Academic/University |
Country | United Kingdom |
Start | 03/2020 |
End | 03/2021 |
Description | Faculty capital bid for portable OCT machine (Alexandra Creavin) |
Amount | £60,000 (GBP) |
Organisation | University of Bristol |
Sector | Academic/University |
Country | United Kingdom |
Start | 09/2015 |
Description | Father involvement and child development in the context of maternal postnatal depression |
Amount | £301,101 (GBP) |
Funding ID | 212664/Z/18/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2019 |
End | 04/2023 |
Description | Fellowship B1088 SSCM.RJ5562 'Molecular and life-course aspects of APOE and TOMM40 in cognition' |
Amount | £35,305 (GBP) |
Funding ID | WT096114/Z/11/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 01/2012 |
End | 12/2015 |
Description | Fellowship Bath B1423 SSCM.RD1832 ' Iodine status in pregnancy & child neurodevelopment' |
Amount | £11,707 (GBP) |
Funding ID | MR/K02132X/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 05/2013 |
End | 05/2016 |
Description | GW4 BioMed MRC DTP (Bushra Farooq) |
Amount | £95,056 (GBP) |
Organisation | GW4 |
Sector | Academic/University |
Country | United Kingdom |
Start | 08/2021 |
End | 03/2025 |
Description | Gene Environment interactions in Mental health trajectories of Youth |
Amount | € 8,107,980 (EUR) |
Funding ID | 101057182 |
Organisation | European Commission H2020 |
Sector | Public |
Country | Belgium |
Start | 05/2022 |
End | 05/2027 |
Description | Gene-Environment Interplay in the Comorbity of PTSD and Disordered Eating |
Amount | £10,909 (GBP) |
Organisation | National Institutes of Health Clinical Center |
Sector | Hospitals |
Country | United States |
Start | 01/2013 |
End | 12/2016 |
Description | Genetic, behavioural and cognitive mechanisms underpinning the association between mother and offspring mental health problems: mental health intergenerational transmission (MHINT) |
Amount | € 1,499,611 (EUR) |
Funding ID | 758813 |
Organisation | European Research Council (ERC) |
Sector | Public |
Country | Belgium |
Start | 12/2017 |
End | 11/2022 |
Description | Genetics of wound healing - BCG scar study |
Amount | £46,467 (GBP) |
Organisation | University of Bristol |
Department | Elizabeth Blackwell Institute for Health Research |
Sector | Academic/University |
Country | United Kingdom |
Start | 11/2016 |
End | 08/2017 |
Description | Gill Althia Francis Early Career Fellowship |
Amount | £138,966 (GBP) |
Funding ID | ECF-2021-092 |
Organisation | The Leverhulme Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2021 |
End | 09/2024 |
Description | GlycA as a novel biomarker linking bacterial-mediated inflammation to adverse cardiometabolic and cardiovascular traits in the young |
Amount | £144,072 (GBP) |
Funding ID | PG/18/45/33814 |
Organisation | British Heart Foundation (BHF) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2018 |
End | 10/2021 |
Description | HDHL-Biomarkers: Early life programming of childhood health: a nutritional and epigenetic investigation (ALPHABET) |
Amount | £101,222 (GBP) |
Funding ID | BB/P028187/1 |
Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2017 |
End | 09/2019 |
Description | Health, maturity, and the gender gap in education (HEALTH-GAP) |
Amount | kr 14,794,000 (NOK) |
Funding ID | 273659 |
Organisation | Norwegian Institute of Public Health |
Sector | Public |
Country | Norway |
Start | 04/2018 |
End | 12/2022 |
Description | Hevolution/AFAR New Investigator Awards in Aging Biology and Geroscience Research |
Amount | $372,900 (USD) |
Organisation | American Federation for Aging Research |
Sector | Charity/Non Profit |
Country | United States |
Start | 12/2022 |
End | 12/2025 |
Description | How and why does ADHD lead to depression in young people? |
Amount | £552,880 (GBP) |
Funding ID | MR/X021769/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 08/2023 |
End | 08/2026 |
Description | How early stress gets under the skin: The role of DNA methylation in the development of youth conduct problems and comorbid symptoms |
Amount | £250,543 (GBP) |
Funding ID | ES/N001273/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 01/2016 |
End | 12/2018 |
Description | Impact of Pediatric Atopic Dermatitis on Neurocognitive Function |
Amount | $171,860 (USD) |
Funding ID | 1K23AR077629-01A1 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 03/2021 |
End | 03/2022 |
Description | Impact of Pediatric Atopic Dermatitis on Neurocognitive Function |
Amount | $171,860 (USD) |
Funding ID | 1K23AR077629-01A1 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 03/2021 |
End | 03/2026 |
Description | Improving future treatment options for menopausal symptoms by using genomics to understand aetiology |
Amount | £808,740 (GBP) |
Funding ID | MR/Y003780/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 11/2023 |
End | 10/2026 |
Description | Improving mental health outcomes in children born with an orofacial cleft: Identifying children at most risk to target clinical provision |
Amount | £608,551 (GBP) |
Funding ID | MR/W020297/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 08/2022 |
End | 08/2025 |
Description | Informing educational interventions using genome-wide data: causal evidence from 573,586 participants of eight cohort studies |
Amount | £222,571 (GBP) |
Funding ID | ES/N000757/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 01/2016 |
End | 12/2018 |
Description | Integrative Cancer Epidemiology Programme: Towards improved causal evidence and enhanced prediction of cancer risk and survival |
Amount | £7,715,113 (GBP) |
Organisation | Cancer Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 05/2020 |
End | 05/2025 |
Description | Interplay between Peer-based Processes and Alcohol Metabolism Genes on Trajectories of Alcohol Use across Adolescence |
Amount | $68,657 (USD) |
Funding ID | 1F31AA025833-01 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 03/2017 |
End | 03/2019 |
Description | Investigating Sex Differences in Risk for Common Mental Health Problems |
Amount | $70,000 (USD) |
Funding ID | 27879 |
Organisation | Brain & Behaviour Research Foundation |
Sector | Charity/Non Profit |
Country | United States |
Start | 01/2020 |
End | 01/2022 |
Description | Investigating five large population-based cohort studies to understand for the precursors of multimorbidity risk. |
Amount | £74,159 (GBP) |
Funding ID | MR/V004905/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 08/2020 |
End | 02/2021 |
Description | Investigating the Epidemiology of CFS/ME in children using the ALSPAC cohort B1425 RD1805 |
Amount | £21,391 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2013 |
End | 09/2015 |
Description | Investigation of the causal effects of atopic eczema on other health outcomes |
Amount | £89,968 (GBP) |
Organisation | British Skin Foundation |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 11/2016 |
End | 10/2018 |
Description | Ipsos Mori: Qualitative research on attitudes around commercial access to health, biomedical and genetic data |
Amount | £2,195 (GBP) |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2015 |
End | 11/2015 |
Description | Is exposure to toxic metals contributing to ethnic and social health inequalities in children and young adults in the UK? |
Amount | £863,011 (GBP) |
Funding ID | MR/X009777/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2023 |
End | 03/2026 |
Description | Klarman Family Foundation B1190 'Epigentics of Eating Disorders : A Lifespan Approach' |
Amount | $132,590 (USD) |
Organisation | The Klarman Family Foundation |
Sector | Charity/Non Profit |
Country | United States |
Start | 05/2012 |
End | 05/2014 |
Description | LONGITUDINAL ADMINISTRATIVE DATA SPINE SCOPING PROJECT GRANT FOR THE SPF UK POPULATION LAB WAVE I |
Amount | £236,901 (GBP) |
Funding ID | ES/S016732/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 12/2018 |
End | 03/2021 |
Description | Life course aetiology of dementia and cognitive decline: improving causal inference |
Amount | £315,800 (GBP) |
Funding ID | MR/P014437/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2017 |
End | 02/2020 |
Description | Lifecourse epidemiology of female reproductive health and its relation to chronic disease |
Amount | £70,205 (GBP) |
Funding ID | MR/M009351/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 12/2014 |
End | 11/2019 |
Description | Lipid-modifying therapy in children with familial hypercholesterolemia |
Amount | £1,491,599 (GBP) |
Funding ID | NIHR134993 |
Organisation | National Institute for Health Research |
Sector | Public |
Country | United Kingdom |
Start | 02/2023 |
End | 08/2028 |
Description | Long-Term Occupational Implications of Preschool Gender-Related Play Behaviour |
Amount | HK$1,400,000 (HKD) |
Funding ID | 17614823 |
Organisation | University of Hong Kong |
Sector | Academic/University |
Country | Hong Kong |
Start | 09/2023 |
End | 09/2026 |
Description | Lung Health @30. Understanding the origins of chronic lung disease and the impact of COVID-19 |
Amount | £191,526 (GBP) |
Organisation | Southmead Hospital Charity |
Sector | Public |
Country | United Kingdom |
Start | 09/2021 |
End | 09/2025 |
Description | MRC Mental Health Pathfinder Award |
Amount | £1,400,000 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2018 |
End | 04/2020 |
Description | MRC Proximity to Discovery Industry Engagement Fund (Tom Richardson) |
Amount | £12,225 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 07/2016 |
End | 05/2017 |
Description | MRC Proximity to Discovery Industry Engagement Fund: Development of ALSPAC Industry Partner and Participant Portal |
Amount | £15,000 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2018 |
End | 09/2018 |
Description | MRC Public Engagement Seed Fund- Matthew Lee |
Amount | £5,000 (GBP) |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 01/2018 |
End | 12/2019 |
Description | Mapping Disparities in Childhood Lead Exposure in England |
Amount | £50,000 (GBP) |
Funding ID | 0011718 |
Organisation | University of Oxford |
Sector | Academic/University |
Country | United Kingdom |
Start | 01/2022 |
End | 05/2022 |
Description | Mapping Disparities in Childhood Lead Exposure in England |
Amount | £49,999 (GBP) |
Funding ID | ECONCIA21-22-30 |
Organisation | University of Oxford |
Sector | Academic/University |
Country | United Kingdom |
Start | 01/2022 |
End | 05/2022 |
Description | Mapping Neurodevelopmental Trajectories for Adult Psychiatric Disorder: ALSPAC-MRI-II |
Amount | £1,791,731 (GBP) |
Funding ID | MR/S003436/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 12/2018 |
End | 11/2022 |
Description | Mapping phenotypic to genetic variability in the High Bone Mass Study |
Amount | £355,425 (GBP) |
Funding ID | 20000 |
Organisation | Versus Arthritis |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 01/2013 |
End | 12/2018 |
Description | Mental health and educational achievement in UK adolescents |
Amount | £131,721 (GBP) |
Funding ID | ES/P00881X/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 06/2017 |
End | 12/2018 |
Description | Mental health and incontinence |
Amount | £525,115 (GBP) |
Funding ID | MR/V033581/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 02/2022 |
End | 11/2024 |
Description | Mental health trajectories following pharmacological and psychological treatment |
Amount | £40,000 (GBP) |
Funding ID | 226686/Z/22/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 07/2022 |
End | 11/2023 |
Description | Mental health trajectories following pharmacological and psychological treatment |
Amount | £40,000 (GBP) |
Funding ID | 226686/Z/22/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 07/2022 |
End | 02/2023 |
Description | Mitochondrial DNA copy number as a phenotypic trait for human diseases in genetic epidemiological studies |
Amount | £384,038 (GBP) |
Funding ID | MR/K002767/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start |
Description | Molecular Genetic and Lifecourse Epidemiology |
Amount | £5,153,712 (GBP) |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2021 |
End | 09/2025 |
Description | Molecular, Genetic and Lifecourse Epidemiology |
Amount | £1,350,000 (GBP) |
Funding ID | 108902/B/15/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2016 |
End | 10/2019 |
Description | Molecular, Genetic and Lifecourse Epidemiology - PhD programme (original programme funding and extension - awarded in 2015, extended by one year in 2017) |
Amount | £1,820,000 (GBP) |
Funding ID | 108902/Z/15/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2016 |
End | 10/2024 |
Description | Molecular, Genetic and Lifecourse Epidemiology. PhD programme to provide 3 PhD students per year (on 4-year PhD programmes) for the intake years 2016/17, 2017/18, 2018/19, 2019/2020. (108902/Z/15/Z). |
Amount | £1,820,000 (GBP) |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 01/2016 |
End | 01/2016 |
Description | Mothers' childhoods and the intergenerational transmission of mental health risk in the context of adversity |
Amount | $179,981 (USD) |
Funding ID | 1K01MH117443-01A1 |
Organisation | National Institute of Mental Health |
Sector | Public |
Country | United States |
Start | 03/2019 |
End | 03/2023 |
Description | Multidimensional Phenotyping in Eczema |
Amount | £89,991 (GBP) |
Organisation | British Skin Foundation |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start |
Description | NIHR Biomedical Research Centre Bristol |
Amount | £20,858,545 (GBP) |
Funding ID | BRC-1215-20011 |
Organisation | National Institute for Health Research |
Sector | Public |
Country | United Kingdom |
Start | 03/2017 |
End | 03/2022 |
Description | NMHB Research Grant SSCM.RD1796 'Behavioral & neurophysicological effects of schizophrenia risk genes' |
Amount | £112,078 (GBP) |
Funding ID | MR/K004360/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2013 |
End | 03/2017 |
Description | Neurodevelopmental disorders: What happens when children grow up and why? |
Amount | £893,353 (GBP) |
Funding ID | 204895/Z/16/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 02/2017 |
End | 01/2021 |
Description | Non-genetic inheritance in human development |
Amount | £995,516 (GBP) |
Funding ID | ID#60828 |
Organisation | The John Templeton Foundation |
Sector | Academic/University |
Country | United States |
Start | 01/2018 |
End | 09/2020 |
Description | Novel epidemiological methods to infer the causal effects of risk factors on neuropsychiatric and cardiovascular disorders |
Amount | $358,957 (AUD) |
Funding ID | APP1079583 |
Organisation | National Health and Medical Research Council |
Sector | Public |
Country | Australia |
Start | 01/2015 |
End | 12/2017 |
Description | NutriPROGRAM: Early-life Nutritional Programming of Metabolic Health through Epigenetic Pathways |
Amount | £267,345 (GBP) |
Funding ID | MR/S036520/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2019 |
End | 08/2022 |
Description | Nutrition and immunity in pregnancy: maternal responses and consequences for offspring |
Amount | £904,296 (GBP) |
Funding ID | MR/W007711/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 09/2023 |
End | 10/2027 |
Description | Our Menopauses: an event for sharing experiences and information about menopause in Bristol |
Amount | £2,619 (GBP) |
Organisation | University of Bristol |
Department | Elizabeth Blackwell Institute for Health Research |
Sector | Academic/University |
Country | United Kingdom |
Start | 05/2017 |
End | 11/2017 |
Description | Oxytocin-Related Predictors of Postpartum Maternal Mood and Mothering B1167 |
Amount | £4,628 (GBP) |
Organisation | National Institutes of Health Clinical Center |
Sector | Hospitals |
Country | United States |
Start | 03/2012 |
End | 03/2014 |
Description | PAR-13-109 Mechanistic Insights from Birth Cohorts (R01) |
Amount | £110,613 (GBP) |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 08/2014 |
End | 08/2019 |
Description | Parenting and children's behavioural problems: Micro- and macro-processes at play in the context of intervention |
Amount | £328,077 (GBP) |
Funding ID | ES/X001865/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 05/2023 |
End | 06/2025 |
Description | Pathogenic mechanisms in post-bereavement psychopathology: Contributions of gene-environment interplay, psychosocial factors, and cognitive ability in two population-based cohorts |
Amount | $190,011 (USD) |
Funding ID | 1K23MH117278-01A1 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 03/2019 |
End | 02/2024 |
Description | Pathways to peak lung function: Genetic, Environmental and lifestyle influences on maximally attainable lung function in young adults |
Amount | £482,295 (GBP) |
Funding ID | MR/M022501/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 04/2015 |
End | 08/2018 |
Description | Pathways to psychosis: investigating environmental, cognitive and genetic mechanisms underlying development of psychotic experiences in young adults |
Amount | £455,151 (GBP) |
Funding ID | MR/M006727/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 05/2014 |
End | 06/2018 |
Description | PhD Studentship - B910 SSCM.RJ5158 'Biological Differences in Smoking Behaviour' |
Amount | £38,715 (GBP) |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 01/2012 |
End | 06/2012 |
Description | Physical and mental health multimorbidity across the lifespan (LIfespaN multimorbidity research Collaborative (LINC)). |
Amount | £3,034,322 (GBP) |
Funding ID | MR/W014416/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 12/2021 |
End | 11/2025 |
Description | Picky Eating in the ALSPAC cohort: Determinants and related health outcomes |
Amount | £1,230 (GBP) |
Organisation | Nestlé (Global) |
Department | Société des Produits Nestlé SA |
Sector | Private |
Country | Switzerland |
Start | 04/2014 |
End | 03/2016 |
Description | Placental contributions to disparities in offspring cardiovascular health across the life course |
Amount | $130,632 (USD) |
Funding ID | 1K01HL165038-01A1 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 05/2023 |
End | 05/2028 |
Description | Population Research Committee - Programme Award Reducing the burden of cancer: causal risk factors, mechanistic targets and predictive biomarkers |
Amount | £4,100,000 (GBP) |
Funding ID | 19169 |
Organisation | Cancer Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 05/2015 |
End | 05/2020 |
Description | Population Research Committee - Project Award B911 SSCM.RJ5681'Breast tissue composition in young women and its pre-natal and early life determinant: a study nested within the ALSPAC' |
Amount | £90,345 (GBP) |
Funding ID | C405/A12730 |
Organisation | Cancer Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2011 |
End | 12/2012 |
Description | Postdoctoral Research Associate/Fellow |
Amount | £178,493 (GBP) |
Organisation | Society for the Study of Addiction |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2021 |
End | 09/2024 |
Description | Predictors and consequences of being a Child in Need or Looked After: data linkage study based on ALSPAC |
Amount | £50,931 (GBP) |
Organisation | University of Bristol |
Department | Elizabeth Blackwell Institute for Health Research |
Sector | Academic/University |
Country | United Kingdom |
Start | 09/2016 |
End | 09/2018 |
Description | Prenatal influences on childhood health: what role for mums and dads? |
Amount | £541,891 (GBP) |
Funding ID | MR/S009310/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 05/2019 |
End | 07/2022 |
Description | Prevention of persistent high levels of depression across adolescence and young adulthood: the role of active ingredients |
Amount | £40,000 (GBP) |
Funding ID | 226698/Z/22/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 07/2022 |
End | 02/2023 |
Description | Prevention of persistent high levels of depression across adolescence and young adulthood: the role of active ingredients |
Amount | £40,000 (GBP) |
Funding ID | 226698/Z/22/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 07/2022 |
End | 03/2023 |
Description | Programme B798 SSCM.RJ5447 'The relationship of the menopausal transition to healthy aging and chronic disease risk' |
Amount | £774,825 (GBP) |
Funding ID | 092830/Z/10/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 06/2011 |
End | 06/2016 |
Description | Psychosocial factors and cancer incidence: a pre-planned meta-analysis of the Psychosocial factors and Cancer |
Amount | € 1,328,435 (EUR) |
Funding ID | VU 20l7-8288 |
Organisation | Dutch Cancer Society (KWF) |
Sector | Charity/Non Profit |
Country | Netherlands |
Start | 03/2018 |
End | 09/2021 |
Description | Psychosocial resilience in children of mothers with depression B1112 |
Amount | £702 (GBP) |
Funding ID | ES/J011657/1 |
Organisation | Economic and Social Research Council |
Department | ESRC Seminar Series |
Sector | Academic/University |
Country | United Kingdom |
Start | 09/2012 |
End | 09/2014 |
Description | Publication Metadata Augmentation |
Amount | £112,678 (GBP) |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 01/2016 |
End | 11/2017 |
Description | Pulmonary epithelial barrier and immunological functions at birth and in early life - key determinants of the development of asthma? |
Amount | £2,560,571 (GBP) |
Funding ID | 108818/Z/15/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 06/2016 |
End | 12/2018 |
Description | Religious belief, health and disease: a family perspective |
Amount | £7,986,970 (GBP) |
Organisation | The John Templeton Foundation |
Sector | Academic/University |
Country | United States |
Start | 08/2021 |
End | 08/2026 |
Description | Religious belief, health and disease: a family perspective. |
Amount | $234,800 (USD) |
Funding ID | 61356 |
Organisation | The John Templeton Foundation |
Sector | Academic/University |
Country | United States |
Start | 07/2019 |
End | 07/2021 |
Description | Religious belief, health and disease: a family perspective. |
Amount | £7,986,970 (GBP) |
Funding ID | 61917 |
Organisation | The John Templeton Foundation |
Sector | Academic/University |
Country | United States |
Start | 08/2021 |
End | 05/2026 |
Description | Research - B1173 SSCM.RD1795 'Study Team for early life Asthma Research (STELAR) |
Amount | £38,406 (GBP) |
Funding ID | MR/K002449/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 01/2013 |
End | 12/2016 |
Description | Research B998 SSCM.RD1782Cussens 'A graphical model approach to pedigree construction using constrained optimisation' |
Amount | £4,602 (GBP) |
Funding ID | G1002312 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 09/2011 |
End | 10/2014 |
Description | Research Grant - B836 SSCM.RK7212 'Maternal thyroid status and offspring development'. |
Amount | £14,529 (GBP) |
Funding ID | ETM/97 |
Organisation | Chief Scientist Office |
Sector | Public |
Country | United Kingdom |
Start | 03/2011 |
End | 03/2013 |
Description | Research Grant BBR Scheme (BBSRC)- B1074 SSCM.RA0543 'A multigenerational prospective resource for integrating genetic, epigenetic and dense phenotypic measures from birth to 18.' |
Amount | £1,186,455 (GBP) |
Funding ID | BB/I025751/1 |
Organisation | Biotechnology and Biological Sciences Research Council (BBSRC) |
Sector | Public |
Country | United Kingdom |
Start | 08/2011 |
End | 08/2013 |
Description | Research into the longer term effects of COVID-19 in non-hospitalised individuals |
Amount | £9,593,946 (GBP) |
Funding ID | COV-LT-0009 |
Organisation | National Institute for Health Research |
Sector | Public |
Country | United Kingdom |
Start | 03/2021 |
End | 04/2024 |
Description | Risky business: Understanding intergenerational persistence in entrepreneurship |
Amount | £548,327 (GBP) |
Funding ID | ES/V016660/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 03/2022 |
End | 09/2022 |
Description | RoSPA: Evaluation of Lifeskills using the ALSPAC Cohort - LASER Safety Education Schemes |
Amount | £19,733 (GBP) |
Organisation | Royal Society for the Prevention of Accidents |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 01/2014 |
End | 10/2014 |
Description | S1P1R genetic profiles in endothelial function and disease |
Amount | € 204,537 (EUR) |
Funding ID | 166002 - CW388001 |
Organisation | Sanofi |
Department | Sanofi Research Division |
Sector | Private |
Country | France |
Start | 03/2016 |
End | 07/2019 |
Description | Seeing is believing in ALSPAC |
Amount | £199,387 (GBP) |
Funding ID | 102215/Z/13/B |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 06/2016 |
End | 10/2016 |
Description | Selection Bias and Mental Health: Towards an Integrated Understanding of Risk Factors for Suicide and Poor Self-rated Mental Health |
Amount | £183,553 (GBP) |
Funding ID | MQF22\22 |
Organisation | MQ Mental Health Research |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2023 |
End | 08/2026 |
Description | Sensitive Periods for the Effects of Depression on Suicide Risk: A longitudinal Study of Gene-Environment Interactions and Epigenetic Mechanisms |
Amount | £224,966 (GBP) |
Funding ID | MQF22\9 |
Organisation | MQ Mental Health Research |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 11/2023 |
End | 10/2026 |
Description | Sensitive periods for prenatal alcohol exposure: a longitudinal study of DNA methylation and subsequent mental health |
Amount | $199,500 (USD) |
Funding ID | 1R21AA030640-01 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 03/2023 |
End | 02/2024 |
Description | Seventh Framework Programme - B1301 SSCM.RQ8840 'Collaborative Projects & Networks of Excellence EXPOsOMICS' |
Amount | € 56,704 (EUR) |
Funding ID | 308610 |
Organisation | European Commission |
Department | Seventh Framework Programme (FP7) |
Sector | Public |
Country | European Union (EU) |
Start | 09/2012 |
End | 09/2016 |
Description | Smoking and Vaping Transitions in Early Adulthood: investigating predictors with longitudinal data |
Amount | £354,821 (GBP) |
Funding ID | PRCPJT-May21\100007 |
Organisation | Cancer Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 02/2022 |
End | 01/2024 |
Description | Smoking and Vaping Transitions in Early Adulthood: investigating predictors with longitudinal data |
Amount | £354,822 (GBP) |
Funding ID | PRCPJT-May21\100007 |
Organisation | Cancer Research UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 02/2022 |
End | 01/2025 |
Description | Solving the 'time puzzle' of epigenetic effects on child mental health (TEMPO) |
Amount | € 1,500,000 (EUR) |
Funding ID | 101039672 |
Organisation | European Research Council (ERC) |
Sector | Public |
Country | Belgium |
Start | 05/2022 |
End | 05/2027 |
Description | Study of Emerging Adulthood and Cardiomatic Health in ALSPAC: The Influence and of growth and other exposures |
Amount | £999,049 (GBP) |
Funding ID | CS/15/6/31468 |
Organisation | British Heart Foundation (BHF) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 06/2015 |
End | 06/2020 |
Description | Synthetic Health Data for Research Support - an exemplar from a birth cohort |
Amount | £4,518 (GBP) |
Funding ID | WorkTribe no: 2374474 |
Organisation | University of Bristol |
Sector | Academic/University |
Country | United Kingdom |
Start | 11/2023 |
End | 06/2024 |
Description | TEMPO |
Amount | € 1,500,000 (EUR) |
Funding ID | 101044076 |
Organisation | European Research Council (ERC) |
Sector | Public |
Country | Belgium |
Start | 05/2022 |
End | 05/2027 |
Description | TENOVUS - Da Silva Focus Group |
Amount | £804 (GBP) |
Organisation | University of Dundee |
Sector | Academic/University |
Country | United Kingdom |
Start | 09/2015 |
End | 11/2015 |
Description | Taking the long view: understanding the precursors and consequences of poor reading comprehension identified in mid-childhood |
Amount | £237,581 (GBP) |
Funding ID | ES/S016333/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 09/2020 |
End | 02/2023 |
Description | Testing cortisol dysregulation as a mediator between early stress and adolescent cardiovascular health |
Amount | $140,054 (USD) |
Funding ID | 1K01HL143159-01A1 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 06/2019 |
End | 06/2024 |
Description | Testing evolutionary hypotheses of social development in the ALSPAC cohort |
Amount | £1,559 (GBP) |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2014 |
End | 09/2015 |
Description | Testing the feasibility and user acceptability of integrating wearable air pollution monitors into population based studies |
Amount | £24,769 (GBP) |
Organisation | University of Bristol |
Department | Elizabeth Blackwell Institute for Health Research |
Sector | Academic/University |
Country | United Kingdom |
Start | 06/2016 |
End | 08/2017 |
Description | The Avon Longitudinal Study for Parents and Children: An international resource for population genomic and lifecourse epidemiology. Core programme support 2014-2019 |
Amount | £7,903,667 (GBP) |
Funding ID | 102215/Z/13/Z |
Organisation | Wellcome Trust |
Department | Wellcome - MRC Cambridge Stem Cell Institute |
Sector | Academic/University |
Country | United Kingdom |
Start | 03/2014 |
End | 03/2019 |
Description | The Avon Longitudinal Study of Parents and Children (ALSPAC): A multi-generation, longitudinal resource focusing on life course health and well-being. |
Amount | £8,327,295 (GBP) |
Funding ID | 217065/Z/19/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 07/2019 |
End | 08/2024 |
Description | The Biosocial Lives of Birth Cohorts |
Amount | £1,009,755 (GBP) |
Funding ID | 219844/Z/19/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2021 |
End | 03/2025 |
Description | The CIVIC Project: A Sustainable Platform for COVID-19 syndromic-surveillance via Health, Deprivation and Mass Loyalty-Card Datasets |
Amount | £233,965 (GBP) |
Funding ID | EP/V053922/1 |
Organisation | Engineering and Physical Sciences Research Council (EPSRC) |
Sector | Public |
Country | United Kingdom |
Start | 02/2021 |
End | 01/2022 |
Description | The Genetic Basis of Urinary Incontinence in Women B956 |
Amount | £44,664 (GBP) |
Organisation | International Urogynecological Association (IUGA) |
Sector | Academic/University |
Country | Global |
Start | 09/2011 |
End | 09/2014 |
Description | The Millennium Cohort Study Sweep 6 (Age 14) Survey (GWAS data collection). |
Amount | £1,000,000 (GBP) |
Organisation | ESRC Impact Acceleration Account Cambridge |
Sector | Academic/University |
Country | United Kingdom |
Start | 02/2018 |
End | 02/2019 |
Description | The Millennium Cohort Study Sweep 6 (Age 14) Survey - extension (GWAS data collection and analysis) |
Amount | £1,052,503 (GBP) |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 01/2017 |
End | 03/2018 |
Description | The causal map of the human phenome |
Amount | £809,240 (GBP) |
Funding ID | 208806 |
Organisation | Sir Henry Dale Fellowships |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2018 |
End | 03/2023 |
Description | The development of genetically-based pathways underlying problematic alcohol use |
Amount | $170,638 (USD) |
Funding ID | 1K01AA027757-01A1 |
Organisation | National Institutes of Health (NIH) |
Sector | Public |
Country | United States |
Start | 05/2020 |
End | 05/2025 |
Description | The developmental role of metabolism, appetite and growth in eating disorders: exploring novel longitudinal risk pathways |
Amount | £215,430 (GBP) |
Funding ID | MR/R004803/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 06/2017 |
End | 09/2020 |
Description | The emergence of self-harm in the first decades of life: a biopsychosocial perspective on developmental dynamics, risk and protective factors |
Amount | SFr. 1,797,424 (CHF) |
Funding ID | 211709 |
Organisation | Swiss National Science Foundation |
Sector | Public |
Country | Switzerland |
Start | 11/2023 |
End | 10/2028 |
Description | The genetic epidemiology of High Bone Mass: skeletal geometry, turnover and fat metabolism, and implications for the wider population |
Amount | £3,322 (GBP) |
Organisation | Versus Arthritis |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 01/2013 |
End | 01/2018 |
Description | The long term impact of COVID-19 on mental health: comparisons between health record linkage and observed longitudinal data |
Amount | £11,020 (GBP) |
Organisation | University of Bristol |
Department | Elizabeth Blackwell Institute for Health Research |
Sector | Academic/University |
Country | United Kingdom |
Start | 08/2020 |
End | 08/2021 |
Description | The long term impact of COVID-19 on mental health: comparisons between health record linkage and observed longitudinal data |
Amount | £11,020 (GBP) |
Funding ID | R105121-249 |
Organisation | University of Bristol |
Department | Elizabeth Blackwell Institute for Health Research |
Sector | Academic/University |
Country | United Kingdom |
Start | 08/2020 |
End | 08/2021 |
Description | The relationship between diet quality in childhood and cardiometabolic health and low-grade chronic inflammation in adolescence and early adulthood |
Amount | £172,563 (GBP) |
Funding ID | FS/19/3/34255 |
Organisation | British Heart Foundation (BHF) |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 04/2019 |
End | 09/2023 |
Description | The role of neighbourhood conditions in mental health responses to the Covid-19 lockdown |
Amount | £8,669 (GBP) |
Funding ID | COV19\200057 |
Organisation | The British Academy |
Sector | Academic/University |
Country | United Kingdom |
Start | 07/2020 |
End | 09/2024 |
Description | Transaction data for population health |
Amount | £1,114,169 (GBP) |
Funding ID | MR/T043520/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 02/2021 |
End | 01/2025 |
Description | TwinsUK (2019-2023) - An Epidemiological and Genomic Resource |
Amount | £3,000,000 (GBP) |
Funding ID | 212904/Z/18/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 01/2019 |
End | 06/2024 |
Description | Type 1 Diabetes Risk in Adults (T1DRA) - A general population study |
Amount | $1,198,616 (USD) |
Organisation | The Leona M. and Harry B. Helmsley Charitable Trust |
Sector | Charity/Non Profit |
Country | United States |
Start | 12/2022 |
End | 11/2025 |
Description | Type 2 Diabetes and Cancer: RD Lawrence Fellowship - Emma Vincent |
Amount | £587,237 (GBP) |
Funding ID | 17/0005587 |
Organisation | Diabetes UK |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2017 |
End | 09/2022 |
Description | UK Department for Business Innovation & Skills (BIS) B931 RK7220 'Further education data linkage projects' |
Amount | £55,000 (GBP) |
Funding ID | BIS/RBU/008/2011 |
Organisation | Department for Business, Energy & Industrial Strategy |
Sector | Public |
Country | United Kingdom |
Start | 02/2011 |
End | 12/2012 |
Description | UK Dept for Business Innovation and Skills B2057 SSCM.RK 'Data Linkage Proposal 2013' |
Amount | £30,000 (GBP) |
Funding ID | BIS/RBU/011/2013 |
Organisation | Department for Business, Energy & Industrial Strategy |
Sector | Public |
Country | United Kingdom |
Start | 09/2013 |
End | 09/2015 |
Description | UK MenCar4 |
Amount | £4,483 (GBP) |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 04/2015 |
End | 09/2015 |
Description | UNICORN (Unified Cohorts Research Network): Disaggregating asthma |
Amount | £2,428,677 (GBP) |
Funding ID | MR/S025340/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2020 |
End | 03/2022 |
Description | UNRAVEL-CAUSALITY |
Amount | € 1,500,000 (EUR) |
Funding ID | 101076686 |
Organisation | European Research Council (ERC) |
Sector | Public |
Country | Belgium |
Start | 03/2023 |
End | 03/2028 |
Description | Understanding Asthma Phenotypes |
Amount | £181,852 (GBP) |
Funding ID | 668954 |
Organisation | European Research Council (ERC) |
Sector | Public |
Country | Belgium |
Start | 01/2016 |
End | 12/2020 |
Description | Understanding Pathways from Environmental Risk to Internalising Problems for Autistic Young People |
Amount | £566,642 (GBP) |
Funding ID | ES/X014207/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 12/2023 |
End | 11/2026 |
Description | Understanding social transitions in emerging adulthood and pathways to later health outcomes |
Amount | £300,000 (GBP) |
Funding ID | 224114/Z/21/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2022 |
End | 08/2026 |
Description | Understanding successful progression to higher education for the white working class and minority ethnic groups (B2215) |
Amount | £14,081 (GBP) |
Organisation | Department for Business, Energy & Industrial Strategy |
Sector | Public |
Country | United Kingdom |
Start | 02/2014 |
End | 07/2015 |
Description | Understanding the Antecedents and Outcomes of Frequent Adolescent Cannabis Use |
Amount | £250,000 (GBP) |
Funding ID | 209158 |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 04/2018 |
End | 05/2022 |
Description | Understanding the Role of Adolescent Dysmenorrhoea as a risk factor for the transition to chronic Pain (RoAdPain) |
Amount | £976,107 (GBP) |
Funding ID | MR/W02697X/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2022 |
End | 03/2025 |
Description | Understanding the downstream effects of early sleep for education and mental health |
Amount | £240,726 (GBP) |
Funding ID | ES/W005972/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 08/2022 |
End | 09/2024 |
Description | Understanding the mechanisms linking cities to psychotic experiences across the lifespan |
Amount | £300,000 (GBP) |
Funding ID | 218632/Z/19/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2020 |
End | 04/2025 |
Description | Unique research opportunities in the genetics and epidemiology of disordered gambling |
Amount | $396,559 (USD) |
Organisation | National Center for Responsible Gaming |
Sector | Charity/Non Profit |
Country | United States |
Start | 06/2017 |
End | 06/2020 |
Description | University of Bristol Widening Participation Grant- Matthew Lee |
Amount | £1,000 (GBP) |
Organisation | University of Bristol |
Sector | Academic/University |
Country | United Kingdom |
Start | 09/2018 |
End | 12/2018 |
Description | Unravelling patterns in social connection for the prevention of depression and anxiety in adolescents and young adults |
Amount | £40,000 (GBP) |
Funding ID | 226701/Z/22/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 07/2022 |
End | 02/2023 |
Description | Unravelling the role of social connection in the prevention of depression and anxiety in young people |
Amount | £40,000 (GBP) |
Funding ID | 226701/Z/22/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 07/2022 |
End | 03/2023 |
Description | Using Mendelian Randomisation to Establish the Causal Role of Cigarette Smoking in Anxiety and Depression |
Amount | £110,594 (GBP) |
Funding ID | MR/J01351X/1 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start |
Description | Using genetic and environmental risks to understand variation in social emotional, and educational outcomes in individuals with language impairments |
Amount | £161,348 (GBP) |
Funding ID | ES/P001955/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 03/2017 |
End | 09/2019 |
Description | Using genetics to understand causal mechanisms underlying adverse outcomes of obese pregnancies |
Amount | £1,391,495 (GBP) |
Funding ID | 220390/Z/20/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2020 |
End | 09/2026 |
Description | Using large cohort studies to identify genetic variants for mechanistic testing in mouse and zebrafish models of wound healing. |
Amount | £788,000 (GBP) |
Organisation | Scar Free Foundation |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 05/2020 |
End | 05/2025 |
Description | Using linked electronic health data to improve eczema diagnosis and outcomes |
Amount | £1,305,851 (GBP) |
Funding ID | 205039/Z/16/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 03/2017 |
End | 02/2019 |
Description | WT Biomedical Resource - B1234 SSCM.RD1793 'The 1958 Birth Cohort Biomedical Resource - facilitating access to data and samples and enhancing future utility' |
Amount | £668,124 (GBP) |
Funding ID | G1001799 |
Organisation | Medical Research Council (MRC) |
Sector | Public |
Country | United Kingdom |
Start | 03/2011 |
End | 12/2014 |
Description | WT Project award - B1118 'Dopamine Function, Cognitive Flexibility and Emotion Regulation' |
Amount | £4,816 (GBP) |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 06/2011 |
End | 01/2012 |
Description | Wellcome Longitudinal Population Study COVID-19 Steering Group and Secretariat |
Amount | £120,585 (GBP) |
Funding ID | 221574/Z/20/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 06/2020 |
End | 07/2021 |
Description | Wellcome Trust Helen Weavers Sir Henry Dale Wellcome: Cytoprotective defence mechanisms during tissue maintenance and repair. |
Amount | £150,829 (GBP) |
Funding ID | 208762 |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 01/2018 |
End | 01/2023 |
Description | Wellcome Trust Research Training Fellowship (Tom Dudding) |
Amount | £187,327 (GBP) |
Funding ID | 201237/Z/16/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2016 |
End | 09/2019 |
Description | What Influences Vaping Harm Perceptions Among Young Adults And How Can They Be Modified? |
Amount | £178,493 (GBP) |
Organisation | Society for the Study of Addiction |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 09/2021 |
End | 09/2024 |
Description | What lies behind the causal impact of body mass index (BMI) level and change on human health? Added value from complementary study design and deep metabolomic phenotyping. |
Amount | £1,850,000 (GBP) |
Funding ID | 202802/Z/16/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2016 |
End | 08/2022 |
Description | What lies behind the causal impact of body mass index (BMI) level and change on human health? Added value from complementary study design and deep metabolomic phenotyping. |
Amount | £1,850,393 (GBP) |
Funding ID | 202802/Z/16/Z |
Organisation | Wellcome Trust |
Sector | Charity/Non Profit |
Country | United Kingdom |
Start | 08/2016 |
End | 08/2023 |
Description | Working memory and its relation to key outcomes in the real world |
Amount | £248,739 (GBP) |
Funding ID | ES/X011135/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 09/2023 |
End | 09/2025 |
Description | Young people's barriers to access mental health services |
Amount | £246,423 (GBP) |
Funding ID | ES/W004682/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 08/2022 |
End | 09/2024 |
Description | Young peoples barriers to access mental health services |
Amount | £246,423 (GBP) |
Funding ID | ES/W004682/1 |
Organisation | Economic and Social Research Council |
Sector | Public |
Country | United Kingdom |
Start | 08/2022 |
End | 09/2024 |
Description | Youth-GEMs |
Amount | € 8,107,980 (EUR) |
Funding ID | 101057182 |
Organisation | European Commission |
Sector | Public |
Country | European Union (EU) |
Start | 05/2022 |
End | 05/2027 |
Title | A Privacy-Preserving Data Management system for MRI and other Large Image Data |
Description | ALSPAC are collecting large volumes of image data through scanning individuals at assessment clinics and also work underway as part of ALSPAC's MRC MH Pathfinder award, through linkage to images held in social media accounts. These images are individually relatively small size, but are being accessed in huge volumes - e.g. a single participants MRI scan can comprise ~12,000 separate image files. Furthermore, many images have embedded identifier values (e.g. NHS ID or name embedded in an MRI scan) or have inherently identifiable components (e.g. an individuals MRI head scan can be used to show a 3D topographic map of a persons face). This leaves study databanks with a challenge to archive large volumes of data, efficiently process them for reuse, and to de-identify them in complex ways. Through MRC MH Pathfinder, the ALSPAC Data Team and Data Linkage Team have developed an image management server with capabilities for archiving, processing and de-identification. This is built on a suite of 'open source' software packages and tuned to the needs of a longitudinal study. This new infrastructure is now operational and facilitating new research in ALSPAC. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2019 |
Provided To Others? | Yes |
Impact | The tool has enabled ALSPAC to lower the charges for the processing of data for reuse from £750 per project to £300 per project. The use of the tool is supporting multiple grant applications, both in the UK and USA. The tool reduces the cost of the grant compared to previous approaches as it impacts on collection and archiving as well as reuse. E.g. Elanor Hinton application to support assessment of the impact of parenthood on maternal and paternal neurobiology and subsequent child development (ALSPAC Reference: B3386, https://proposals.epi.bristol.ac.uk/?q=node/129988). The tool is supporting the MRC funded grant led by Professor Anthony David (UCL) (ALSPAC Reference: B3035, https://proposals.epi.bristol.ac.uk/?q=node/127353). |
Title | ALSPAC Biosamples and DNA resources |
Description | Over 1.2 million aliquots biosamples taken at various timepoints from ALSPAC participants. The bioresource is available to the scientific community for research. Although the resource was initiated in 1991 it is an active collection with new samples being collected and made available constantly. |
Type Of Material | Biological samples |
Provided To Others? | Yes |
Impact | Samples have been made available for numerous ALSPAC projects. The resource received the UK Biobank of the Year award in 2018 reflecting the impact of studies utalising the samples. |
URL | http://www.bristol.ac.uk/alspac/researchers/our-data/biological-resources/ |
Title | Checklist for synthetic data production |
Description | In order to encourage the use of synthetic data, we have developed a checklist (similar to our publications checklist) for resarchers use to adhere to certain rules for data development. A data note has been published to accompany this: https://wellcomeopenresearch.org/articles/9-57 |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2023 |
Provided To Others? | Yes |
Impact | not yet |
URL | https://www.bristol.ac.uk/media-library/sites/alspac/documents/ALSPAC-syntheticdata-checklist.pdf |
Title | Data Access Agreement (DAA) data sharing contract |
Description | The data access agreement is a new data sharing contract which is compatible with contemporary legislative (e.g. General Data Protection Regulations) and research governance expectations. It aligns with ALSPAC's Online Proposal System for efficient generation of specified and controlled data requests. Importantly, the DAA enables the replication of third-party data owner requirements and the addition of particular governance controls for specific datasets (e.g. geo-spatial datasets), and as such is an important element in ALSPAC's process to allow onward sharing of linked health, geo-spatial and social records. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2018 |
Provided To Others? | Yes |
Impact | The DAA is a central component in ALSPAC's negotiations with NHS Digital to enable onward sharing of linked records. |
URL | http://www.bristol.ac.uk/alspac/researchers/access/ |
Title | Data Privacy Impact Assessment Process |
Description | A new privacy assessment tool for ALSPAC which enables the assessment of data flows (i.e. new record linkages or new data sharing with research users) in line with EU General Data Protection Regulation requirements. The tool allows the assessment of diverse risks and particular research scenarios (e.g. the use of geocoded data in the research process, the additional sensitivities of using mental or sexual health records in research investigations. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2018 |
Provided To Others? | No |
Impact | Ensuring ALSPAC data sharing is legally compliant. |
Title | Deep freeze of ALSPAC datasets |
Description | A regular snapshot of our current data is now backed up annually off site. This is in addition to central IT regular back up systems |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2021 |
Provided To Others? | No |
Impact | Imperative for disaster recovery |
Title | Deep freeze of ALSPAC datasets |
Description | A regular snapshot of our current data is now backed up annually off site. This is in addition to central IT regular back up systems. The last deep freeze was completed in the Spring of 2023 |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2023 |
Provided To Others? | No |
Impact | Imperative for disaster recovery |
Title | Development of ALSPAC Explore |
Description | ALSPAC Explore is our public facing data catalogue. This is a component of the Obiba Open Source project suite and is hosted by University of Bristol IT services. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2021 |
Provided To Others? | Yes |
Impact | Ultimately this tool will improve the discoverability and accessibility of ALSPAC data. The tool has been launched internally and is undergoing testing for external researchers to use as their primary tool for identifying ALSPAC variables. |
URL | https://alspac-explore.bristol.ac.uk/mica-web/ |
Title | Development of a rapid online survey regarding plans at Christmas 2021 in light of 'Plan B' |
Description | ALSPAC was approach by Dr Ellen Brooks-Pollock, UOB and member of SPI-M to rapidly question our participants about their plans over th festive period and determine whether they might change following the Government's announcement of Plan B mitigation emausres |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2022 |
Provided To Others? | Yes |
Impact | Published on the Government website: https://www.gov.uk/government/publications/university-of-bristol-impact-of-voluntary-risk-mitigation-behaviour-on-the-magnitude-of-a-covid-19-omicron-variant-wave-in-england-11-january-2022 Pre-print and peer reviewed paper to follow alongside a DOI for the data,. |
URL | https://www.gov.uk/government/publications/university-of-bristol-impact-of-voluntary-risk-mitigation... |
Title | Development of online consent procedures |
Description | In order to facilitate virtual clinics the systems team have successfully tested and implemented the collection of online consent for remote measures. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2020 |
Provided To Others? | No |
Impact | Consent is vital for all 'face to face' measures we would normally collect. As we have moved to remote data collection the method for obtaining consent has had to change. |
Title | Development of virtual online visits |
Description | To replace face to face visits in the times of pandemic and to provide an alternative offering to participants who do not want to or cannot attend a clinic visit in person. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2021 |
Provided To Others? | No |
Impact | Will minimise attrition. |
Title | Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference |
Description | Detailed phenotyping is required to deepen our understanding of the biological mechanisms behind genetic associations. In addition, the impact of potentially modifiable risk factors on disease requires analytical frameworks that allow causal inference. We have described the characteristics of Recall-by-Genotype (RbG) as a study design aimed at addressing both these needs. We have considered the efficacy and practicality of the RbG approach, provide a catalogue of UK-based resources for such studies and present an online RbG study planner. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2017 |
Provided To Others? | Yes |
Impact | Recent development. notably described here: https://www.nature.com/articles/s41467-018-03109-y - with related software - see the link below. |
URL | http://www.bristol.ac.uk/integrative-epidemiology/faciliitiesresources/software/ |
Title | Handling ethical queries and feedback within studies of genetic sequence data. |
Description | This work provides a discussion and framework for the handling of incident and pertinent findings in the analysis of sequence data. |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | NA |
URL | http://www.nature.com/ejhg/journal/v22/n9/full/ejhg2013290a.html |
Title | Implementation of DataSHIELD for the InterConnect project |
Description | Prof Paul Burton worked with Professor Nick Wareham's MRC-Epidemiology Unit led, Interconnect Project which is funded by the European Union to implement DataSHIELD on a consortium of eight cohorts/biobanks (seven European, one North American) including ALSPAC. This required a standard implementation of the DataSHIELD structure for remote federated analysis of "horizontally partitioned" data (different sources hold the same variables on different individuals). |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2017 |
Provided To Others? | Yes |
Impact | The implementation of DataSHIELD has been successfully led by Tom Bishop who is the lead DataSHIELD development team member based in Cambridge. Prof Burton's team have provided ongoing support of both the technology and statistical methods. This work was successful and a paper is currently under review at the International Journal of Epidemiology: |
URL | http://www.interconnect-diabetes.eu/ |
Title | Implementation of new data warehouse and external data catalogue |
Description | We are in the process of moving all data access to Opal (data warehouse) and to add Mica (public catalogue) as a data discovery option. This will be known externally as ALSPAC Explore. Opal and Mica are both components of the Obiba Open Source project suite and are hosted by University of BRistol IT services. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2019 |
Provided To Others? | Yes |
Impact | Mica and Opal talk to each other; a researcher can compile their data list as they search and it can be imported directly into Opal, reducing work for both researchers and data buddies - Realtime frequencies of data in Opal will be displayed in Explore; this drastically reduces the amount of work going into the data dictionary. - Explore much more efficient searching system which should enhance data discoverability - Future developments may include the use of Datashield for federated analyses, networking with other studies using the same software - Enables the use of Ontologies (currently CLOSER topics and Maelstrom classification). |
URL | https://alspac-data.bristol.ac.uk/mica-web/ |
Title | Improved access policy |
Description | A much improved Access Policy has been written and made available via the website |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2014 |
Provided To Others? | Yes |
Impact | Ensures rules regarding data access are clear and transparent |
URL | http://www.bristol.ac.uk/alspac/researchers/data-access/ |
Title | Imputed Genome Wide (GWAS) single nucleotide polymorhism (SNP) dataset |
Description | Imputation of 526,688 SNPs post quality control to the HapMap CEU population, release 22 for subjects in ALSPAC with GWAS data. |
Type Of Material | Biological samples |
Year Produced | 2013 |
Provided To Others? | Yes |
Impact | The data have been used in several high impact publications including: Anttila, V. et al. 2013. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nat Genet. 2013 Aug;45(8):912-7 Hinds, D.A. et al. (In press). A meta-analysis of self-reported allergy identifes shared and allergy-specifc susceptibility loci Nat Genet. 2013 Aug;45(8):907-11 Evans, D.M. et al. 2013. Genome-Wide Association Study Identifies Loci Affecting Blood Copper, Selenium and Zinc. Hum Mol Genet. 2013 Oct 1;22(19):3998-4006 |
Title | Introduction of REDCap as a data collection tool |
Description | REDCap has been successfuly introduced as the data collection tool used in clinic based data collection. It is also about to be used for the first time for online questionnaire data collection |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | Streamlines data collection; minimising errors |
URL | http://www.project-redcap.org/ |
Title | Introduction of cost recovery, replacing data buddy fee |
Description | At the request of the funders a number of salaries related to data provision are now recovered directly from external researchers who pay a variable amount (depending on the amount and type of data) to access ALSPAC data |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | Cost recovery income is monitored very closely - currently the model is not bringing in sufficient income. It will be reassessed at the end of year 1. |
Title | Longitudinal Linkage Collaboration |
Description | Six National Core Studies have been set up for COVID-19 research, funded by the UK Government. These studies aim to answer pressing COVID-19 questions through accelerating progress in establishing a pioneering health data and research infrastructure for the future. The UK LLC is operated by the University of Bristol and the University of Edinburgh. It is embedded within the COVID-19 Longitudinal Health and Wellbeing National Core Study. This work uses data provided by study participants and patients collected through longitudinal studies, or as part of their care and support. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2022 |
Provided To Others? | Yes |
Impact | Coordination of cohorts and record linkage,. |
URL | https://ukllc.ac.uk |
Title | MRI images data pipeline |
Description | Streamlined release of re-indexed MRI images on request. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2020 |
Provided To Others? | Yes |
Impact | Data note listed below details the data available through the pipeline. This has resulted in reduced cost recovery charges for this data. |
URL | https://wellcomeopenresearch.org/articles/5-203 |
Title | Management of a whole genome sequencing project and data |
Description | This work presents lessons learnt from the management of a whole genome sequence data project. |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | This work has been published: Genome Med. 2013 Nov 15;5(11):100. doi: 10.1186/gm504. eCollection 2013. Implementing a successful data-management framework: the UK10K managed access model. Muddyman D1, Smee C1, Griffin H2, Kaye J2. |
Title | Management of clinical information within a whole genome sequence project |
Description | This work considers and advises on how to handle data which is clinically important within the context of a whole genome sequence project. |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | This work has been published: Eur J Hum Genet. 2014 Sep;22(9):1100-4. doi: 10.1038/ejhg.2013.290. Epub 2014 Jan 15. Managing clinically significant findings in research: the UK10K example. Kaye J1, Hurles M2, Griffin H1, Grewal J3, Bobrow M4, Timpson N5, Smee C2, Bolton P6, Durbin R2, Dyke S2, Fitzpatrick D7, Kennedy K2, Kent A8, Muddyman D2, Muntoni F9, Raymond LF4, Semple R4, Spector T10; UK 10K. |
Title | Metadata: Variable catalogue |
Description | Improved metadata provision - a simple list of variables available so that researchers can simply copy and paste in order to provide lists of variables as part of their data request under cost recovery |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2014 |
Provided To Others? | Yes |
Impact | Improves accessibility/discoverability of data |
URL | http://www.bristol.ac.uk/alspac/researchers/data-access/data-dictionary/ |
Title | Multiple Imputation DOCtor (midoc) R package |
Description | Missing data is a common issue in health and social research, often addressed by multiple imputation (MI). MI is a flexible and general approach, with a suite of software packages. However, using MI in practice can be complex. Application of MI involves multiple decisions which are rarely justified or even documented, and for which little guidance is available. The Multiple Imputation DOCtor (midoc) R package is a decision-making system which incorporates expert, up-to-date guidance to help you choose the most appropriate analysis method when there are missing data. IT has been designed by ALSPAC researchers using ALSPAC data as key use-cases. Workships are currently being set up for ALSPAC researchers to demonstrate its use. Funded by MRC |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2023 |
Provided To Others? | No |
Impact | Still being finalised. |
URL | https://github.com/elliecurnow/midoc |
Title | Online booking system |
Description | Bespoke software development allowing study participants to book appointments online to attend the clinical assessment |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | Improved participant experience |
Title | Online proposal for data access system |
Description | Bespoke software development where researchers can enter details of new proposals to access ALSPAC data, system processes these and logs all relevant supporting information and agreements together (see https://proposals.epi.bristol.ac.uk/) |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | Improved system providing speedier access to ALSPAC data. We have been approached by other research groups interested in using this system and we are exploring options around how we might make this available to others. |
URL | https://proposals.epi.bristol.ac.uk/ |
Title | Online questionnaire system |
Description | Successful development of an effective online questionnaire system used by participants to complete ALSPAC questionnaires via the study website |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | More efficient and cost effective collection of data from research particpants |
Title | Power calculations for the undertaking of genetic sequence analysis of rare variants. |
Description | This work provides a framework within which power calculations for the analysis of rare variants from genetic sequence data can be undertaken. |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | NA |
URL | http://onlinelibrary.wiley.com/doi/10.1002/gepi.21797/abstract |
Title | Protocol for genetic annotation and characterization |
Description | We have developed a tool which annotates all genetic variants within a user specified region of the human genome. These annotations are collated from various databases, including information such as (but not limited to) predicted consequence, predicted deleterious impact, trait associations, quantitative trait loci (i.e. expression, methylation, chromatin, metabolomics, proteomics), regulatory information, biological pathways and druggable/trials info. |
Type Of Material | Model of mechanisms or symptoms - in vitro |
Provided To Others? | No |
Impact | As the tool is unreleased there has been no impact yet. However, we intend to share the tool with the French pharmaceutical company Sanofi once it is ready as part of our on-going collaboration. |
Title | Protocol for recall by genotype study - sleep |
Description | This work provides a framework within which recall by genotype studies can be undertaken. |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | This description is now published: BMC Med Genet. 2015 Oct 24;16:96. doi: 10.1186/s12881-015-0244-4. Genetics, sleep and memory: a recall-by-genotype study of ZNF804A variants and sleep neurophysiology. |
URL | http://www.biomedcentral.com/1471-2350/15/13 |
Title | Protocol for recall by genotype study - smoking |
Description | This work provides a written protocol for the undertaking of recall by genotype studies. |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | This work is now published: BMC Med Genet. 2014 Jan 22;15:13. doi: 10.1186/1471-2350-15-13. A recall-by-genotype study of CHRNA5-A3-B4 genotype, cotinine and smoking topography: study protocol. Ware JJ1, Timpson N, Davey Smith G, Munafò MR. |
Title | Providing a genomic teaching resource |
Description | Teaching the methods and approaches used in genetic epidemiology is most effective when realistic data is available for students to use. We have scrambled the ALSPAC genetic data in order to preserve the genetic characteristics of the dataset whilst making the data non-disclosive of the participants. |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | This scrambled dataset has been used in at least six short courses on genetic epidemiology to date, and is continually used to teach students. |
Title | Recall by Genotype Study Planner - app |
Description | This is an online "shiny app" which is designed to accompany a position paper describing the principal and application of Recall by Genotype as a research method. It allows the calculation of statistical power and study cost (in comparison to other more conventional designs) in a series of study formats. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2016 |
Provided To Others? | Yes |
Impact | This research tool will be released in full form with the publication of the Recall by Genotype position paper. |
Title | Statistical methods for approaching lifecourse methods |
Description | A number of groups are working on methods for analysing longitudinal data from the study producing both novel methods and building on existing methods to make best use of the repeat measures ALSPAC has. This area of work has a particular focus on lifecourse models. |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2015 |
Provided To Others? | Yes |
Impact | A number of papers have been published including: Smith AD, Hardy R, Heron J, Joinson CJ, Lawlor DA, Macdonald-Wallis C, Tilling K. A structured approach to hypotheses involving continuous exposures over the life course. Int J Epidemiol. 2016 Aug;45(4):1271-1279. Epub 2016 Jul 1. Howe LD, Smith AD, Macdonald-Wallis C, Anderson EL, Galobardes B, Lawlor DA, Ben-Shlomo Y, Hardy R, Cooper R, Tilling K, Fraser A. Relationship between mediation analysis and the structured life course approach. Int J Epidemiol. 2016 Aug;45(4):1280-1294. Epub 2016 Sep 27. Smith AD, Heron J, Mishra G, Gilthorpe MS, |
Title | Statistical methods for dealing with repeat measures |
Description | A number of groups are working on methods for analysing longitudinal data from the study producing both novel methods and building on existing methods to make best use of the repeat measures ALSPAC has. This covers a variety of different types of data and areas of research including growth, risky behaviours, diet and health outcomes |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2010 |
Provided To Others? | Yes |
Impact | A number of papers have been published. A few relevant examples are provided below: Anderson EL, Tilling K, Fraser A, Macdonald-Wallis C, Emmett P, Cribb V, Northstone K, Lawlor DA, Howe LD. Estimating Trajectories of Energy Intake Through Childhood and Adolescence Using Linear-Spline Multilevel Models. Epidemiology. Epub 2013 May 21. PMID: 23698751 Howe LD, Tilling K, Galobardes B, Davey Smith G, Gunnell D, Lawlor DA. Socioeconomic differences in childhood growth trajectories: at what age do height inequalities emerge? J Epidemiol Community Health. 2012;66(2):143-8. PMID:20724285. Heron J, Macleod J, Munafo MR, Melotti R, Lewis G, Tilling K, Hickman M. Patterns of Alcohol Use in Early Adolescence Predict Problem Use at Age 16. Alcohol Alcohol. 2012;47(2):169-77. PMID:22215001. Macdonald-Wallis C, Lawlor D, Palmer T, Tilling K. Multivariate multilevel spline models for parallel growth processes: application to weight and mean arterial pressure in pregnancy. Stat Med. 2012;31(26):3147-6. PMID:22733701. |
Title | Statistical methods for examining missing data/misclassification |
Description | A number of statisticians are working on methods using linkage data to investigate missing data and/or misclassification of exposures/outcomes. This covers a number of different data sources and areas of research including education, mental health and wellbeing |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2015 |
Provided To Others? | Yes |
Impact | A number of papers have been published including: Cornish R, Tilling K, Boyd A, Macleod J, Van Staa T. Using linkage to electronic primary care records to evaluate recruitment and nonresponse bias in the Avon Longitudinal Study of Parents and Children. Epidemiology. 2015 Jul;26(4):e41-2. doi: 10.1097/EDE.0000000000000288. Cornish RP, Tilling K, Boyd A, Davies A, Macleod J. Using linked educational attainment data to reduce bias due to missing outcome data in estimates of the association between the duration of breastfeeding and IQ at 15 years. Int J Epidemiol. 2015 Jun;44(3):937-45. doi: 10.1093/ije/dyv035. Mars B, Cornish R, Heron J, Boyd A, Crane C, Hawton K, Lewis G, Tilling K, Macleod J, Gunnell D. Using Data Linkage to Investigate Inconsistent Reporting of Self-Harm and Questionnaire Non-Response. Arch Suicide Res. 2016;20(2):113-41. doi: 10.1080/13811118.2015.1033121. Epub 2016 Jan 20. Cornish RP, John A, Boyd A, Tilling K, Macleod J. Defining adolescent common mental disorders using electronic primary care data: a comparison with outcomes measured using the CIS-R. BMJ Open. 2016 Dec 1;6(12):e013167. doi: 10.1136/bmjopen-2016-013167. |
Title | Statistical thresholds for the analysis of whole genome sequence data. |
Description | This work provides guidelines for the setting of statistical thresholds when analysing whole genome sequence data. |
Type Of Material | Improvements to research infrastructure |
Provided To Others? | No |
Impact | This work has been published: Genet Epidemiol. 2014 May;38(4):281-90. doi: 10.1002/gepi.21797. Epub 2014 Feb 14. Estimating genome-wide significance for whole-genome sequencing studies. Xu C1, Tachmazidou I, Walter K, Ciampi A, Zeggini E, Greenwood CM; UK10K Consortium. |
Title | UK10K Project Dalliance Genome Browser |
Description | The UK10K Genome Browser is based on the Biodalliance platform (Down et al., Bioinformatics 2011), designed to facilitate the retrieval of genotype-phenotype association results from the UK10K Cohorts Project (Walter et al, Nature 2015), and their visualisation in the context of different annotation features. |
Type Of Material | Physiological assessment or outcome measure |
Provided To Others? | No |
Impact | Allows researchers to easily access key results from the cohort arm of the UK10K and generate new hypothesis based on this dataset |
URL | http://www.uk10k.org/dalliance.html |
Title | Variable Search Tool |
Description | A web application has been developed which performs rapid searching of all variables that are readily accessible in the resource. Using this in conjunction with the detailed data dictionary eases discoverability of the ALSPAC data for potential users. This web based app was formally released in May 2018 |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2018 |
Provided To Others? | Yes |
Impact | The release of the tool has facilicated easy searching for variables and is used widely by both internal and external researchers |
URL | http://variables.alspac.bris.ac.uk/ |
Title | Web resource for the provision of UK10K sequence data, the display of results, related information and ethical documentation. |
Description | This resource provides a collection of material from the UK10K project which involved the sequencing of over 4000 population based human genomes. Resources include: (i) access to raw data (ii) results from association study analysis (rare and common genetic variants) through an integrated browser (iii) ethical documentation (iv) related publications and management information |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2013 |
Provided To Others? | Yes |
Impact | NA |
URL | http://www.uk10k.org |
Title | Wellcome LPS COVID Questionnaire bank |
Description | The ALSPAC team has led the development of the Wellcome funded Longitudinal Population Studies COVID questionnaire bank. This facilitates comparable research across longitudinal studies. Together with Generation Scotland, ALSPAC form the secretariat for the Wellcome LPS COVID group. ALSPAC has provided the questionnaire in REDCap format on demand |
Type Of Material | Improvements to research infrastructure |
Year Produced | 2020 |
Provided To Others? | Yes |
Impact | The questionnaire bank facilitates research across multiple studies about the COVID pandemic. The questions were designed to help researchers explore changes using the same validated questions to the lives of cohort participants the UK and elsewhere. |
URL | https://www.bristol.ac.uk/alspac/researchers/wellcome-covid-19/ |
Title | ALSPAC 'GP' dataset of linked primary care records (1991-2018) |
Description | These data are the coded values - relating to participant symptoms, diagnoses, treatments, care - extracted from GP primary care records of ALSPAC participants receiving care in England. The records are linked from EMIS Ltd (a GP software system company) and are managed by the ALSPAC data linkage team. |
Type Of Material | Database/Collection of data |
Year Produced | 2018 |
Provided To Others? | Yes |
Impact | The data are being used projects led by: 1) Professor Stan Zammit as part of the ALSPAC - Born in Bradford MRC MH Pathfinder Award (ALSPAC Reference: B3060, https://proposals.epi.bristol.ac.uk/?q=node/129688). 2) Dr Alison Teyhan as part of the ALSPAC - Born in Bradford MRC MH Pathfinder Award (ALSPAC Reference: B3060, https://proposals.epi.bristol.ac.uk/?q=node/129688). 3) Dr Rosie Cornish as part of the ALSPAC - Born in Bradford MRC MH Pathfinder Award (ALSPAC Reference: B3060, https://proposals.epi.bristol.ac.uk/?q=node/129688). 4) Professor Dheeraj Rai to study Adolescent and adult mental health outcomes of autism and autistic traits (ALSPAC Reference: B2622, https://proposals.epi.bristol.ac.uk/?q=node/127702) 5) Professor Hilary Pinnock for the derivation of a clinical prediction rule for the diagnosis of asthma (ALSPAC Reference: B2830, https://proposals.epi.bristol.ac.uk/?q=node/127536) 6) Professor Sinead Langan as part of a program to establish efficient methods to understand medical and social outcomes associated with eczema (ALSPAC Reference: B2606, https://proposals.epi.bristol.ac.uk/?q=node/127717). |
URL | http://www.bristol.ac.uk/alspac/researchers/our-data/linkage/ |
Title | ALSPAC 'HES' Hospital Episode Statistics records |
Description | These are minimum returns of Hospital Episode Statistics secondary care records of ALSPAC participants receiving care in England. The records are linked from NHS Digital and accessed under a NHS Digital - University of Bristol Data Sharing Agreement (managed by the ALSPAC data linkage team). |
Type Of Material | Database/Collection of data |
Year Produced | 2019 |
Provided To Others? | Yes |
Impact | The data are being used projects led by: 1) Professor Stan Zammit as part of the ALSPAC - Born in Bradford MRC MH Pathfinder Award (ALSPAC Reference: B3060, https://proposals.epi.bristol.ac.uk/?q=node/129688). 2) Dr Alison Teyhan as part of the ALSPAC - Born in Bradford MRC MH Pathfinder Award (ALSPAC Reference: B3060, https://proposals.epi.bristol.ac.uk/?q=node/129688). 3) Dr Rosie Cornish as part of the ALSPAC - Born in Bradford MRC MH Pathfinder Award (ALSPAC Reference: B3060, https://proposals.epi.bristol.ac.uk/?q=node/129688). |
URL | http://www.bristol.ac.uk/alspac/researchers/our-data/linkage/ |
Title | ALSPAC 'Looked After' and 'Children In Need' linked social care records |
Description | These are records of children taken into state care and children classifed as 'in Need'. The records are linked from Department for Education National Pupil Database and accessed under a DfE - University of Bristol Data Sharing Agreement (managed by the ALSPAC data linkage team). While access is currently restricted to the project team, we are exploring mechanisms to widen access using the new powers of the Digital Economy Act and in partnership with the Administrative Data Research-UK. |
Type Of Material | Database/Collection of data |
Year Produced | 2019 |
Provided To Others? | No |
Impact | The data are being used in a project led by Professor John Macleod and Dr Alison Teyhan as part of the ALSPAC - Born in Bradford MRC MH Pathfinder Award (ALSPAC Reference: B3060, https://proposals.epi.bristol.ac.uk/?q=node/129688). This research has resulted in an academic paper: Teyhan A, Boyd A, Wijedasa D, Macleod J. Early life adversity, contact with children's social care services and educational outcomes at age 16 years: UK birth cohort study with linkage to national administrative records. BMJ open. 2019 Oct 1;9(10):e030213. We have also published a blog article emphasising the value of the novel methodologies in this research: https://www.closer.ac.uk/news-opinion/blog/filling-gaps-boosts-evidence-vulnerable-children/ |
URL | http://www.bristol.ac.uk/alspac/researchers/our-data/linkage/ |
Title | ALSPAC 'MHSDS' Data Set of Mental Health & Learning Difficulties Community Care Interactions |
Description | These are minimum returns of Mental Health community care records of ALSPAC participants receiving care in England. The records are linked from NHS Digital and accessed under a NHS Digital - University of Bristol Data Sharing Agreement (managed by the ALSPAC data linkage team). |
Type Of Material | Database/Collection of data |
Year Produced | 2019 |
Provided To Others? | Yes |
Impact | The data are being used in a project led by Professor Stan Zammit as part of the ALSPAC - Born in Bradford MRC MH Pathfinder Award (ALSPAC Reference: B3060, https://proposals.epi.bristol.ac.uk/?q=node/129688). |
URL | http://www.bristol.ac.uk/alspac/researchers/our-data/linkage/ |
Title | ALSPAC 'STORK' dataset of linked maternity records (1990-1992) |
Description | The ALSPAC Data Linkage team have recently (2019-2020) cleaned and documented the STORK dataset of midwifery and birth delivery records for those index participants born in either of the two main maternity hospitals in Bristol (approx. 85% of enrolled participants). These data are available for access to the bona-fide research community via the ALSPAC access mechanism. A 'Data Note' publication is being prepared to contribute documentation and to aid the discoverability of the new dataset. |
Type Of Material | Database/Collection of data |
Year Produced | 2019 |
Provided To Others? | Yes |
Impact | The data are being used by Dr Katie Harron (UCL) as part of her Wellcome Trust LPS (Aim 2) Award (ALSPAC reference B3002, https://proposals.epi.bristol.ac.uk/?q=node/127384). The data are being used by Dr Alison Teyhan (University of Bristol) as part of the ALSPAC Born-in-Bradford MRC MH Pathfinder award (ALSPAC reference B3060, https://proposals.epi.bristol.ac.uk/?q=node/129688). |
URL | http://www.bristol.ac.uk/alspac/researchers/our-data/linkage/ |
Title | ALSPAC - genomewide genetic data resources |
Description | Currently I am responsible for the delivery of genomewide data from the ALSPAC collection. With over 18000 mother and child samples, this is being increased to include partners/fathers and to make best use of newly available deep imputation panels. |
Type Of Material | Database/Collection of data |
Provided To Others? | No |
Impact | The resource is fully described online and is available to the academic community. |
URL | http://www.bris.ac.uk/alspac/ |
Title | ALSPAC UK Secure eResearch Platform for the secure analysis of sensitive data |
Description | The ALSPAC data linkage team have worked with the UK Secure eResearch Platform team (University of Swansea) to establish an 'ALSPAC UKSeRP' secure research server and for the secure analysis of sensitive data, particularly linked routine records accessed under contract. The ALSPAC UKSeRP has been embedded in ALSPAC's linkage ethics and data sharing agreements. It has also been embedded in the study's ISO27001 certified Information Security Management System (ISMS). This is now providing the infrastructure for sharing data with bona fide users, subject to ALSPAC's project approvals process. The management of the system is governed by Standard Operating Procedures and is subject to internal and external audit assessments. We are currently in a 'Beta User' phase, once the mechanisms are fully established the resource will be promoted more widely. |
Type Of Material | Data handling & control |
Year Produced | 2019 |
Provided To Others? | Yes |
Impact | The ALSPAC UKSeRP 'Beta User' phase is currently being used for 6 research programmes, 4 based at the University of Bristol, 1 at the University of Edinburgh and 1 at LSHTM. It is the key infrastructure for enabling the ALSPAC Born In Bradford MRC MH Pathfinder deliverables. The infrastructure is being used projects led by: 1) Professor Stan Zammit as part of the ALSPAC - Born in Bradford MRC MH Pathfinder Award (ALSPAC Reference: B3060, https://proposals.epi.bristol.ac.uk/?q=node/129688). 2) Dr Alison Teyhan as part of the ALSPAC - Born in Bradford MRC MH Pathfinder Award (ALSPAC Reference: B3060, https://proposals.epi.bristol.ac.uk/?q=node/129688). 3) Dr Rosie Cornish as part of the ALSPAC - Born in Bradford MRC MH Pathfinder Award (ALSPAC Reference: B3060, https://proposals.epi.bristol.ac.uk/?q=node/129688). 4) Professor Dheeraj Rai to study Adolescent and adult mental health outcomes of autism and autistic traits (ALSPAC Reference: B2622, https://proposals.epi.bristol.ac.uk/?q=node/127702) 5) Professor Hilary Pinnock for the derivation of a clinical prediction rule for the diagnosis of asthma (ALSPAC Reference: B2830, https://proposals.epi.bristol.ac.uk/?q=node/127536) 6) Professor Sinead Langan as part of a program to establish efficient methods to understand medical and social outcomes associated with eczema (ALSPAC Reference: B2606, https://proposals.epi.bristol.ac.uk/?q=node/127717). |
URL | http://www.bristol.ac.uk/alspac/researchers/our-data/linkage/ |
Title | ALSPAC Whole Exome Sequence Data Trios |
Description | Whole Exome Sequence (WES)data has been generated on ~ 9,000 ALSPAC G1 individuals and ~ 1,700 of their mothers (G0) and 1,700 of their fathers (G0). The data set will include WES from ~1,700 family trios. Data is now available for researchers in raw format and will be processed and publicised in 2023 |
Type Of Material | Database/Collection of data |
Year Produced | 2023 |
Provided To Others? | Yes |
Impact | This data has greatly enhanced ALSPAC's comprehensive omics catalogue and is a valuable resource for genetic epidemiology |
Title | ARIES-Explorer |
Description | ARIES-Explorer provides an openly accessible web interface to explore epigenome-wide methylation data from the Accessible Resource for Integrated Epigenomics Studies |
Type Of Material | Database/Collection of data |
Year Produced | 2013 |
Provided To Others? | Yes |
Impact | Cited in a key review in the field (Mill et al, Nature Reviews Genetics, VOLUME 14 | AUGUST 2013 | 585). 419 unique visitors to the site in its first month of operation. |
URL | http://ariesepigenomics.org.uk/ariesexplorer |
Title | Avon & Somerset Regional police records |
Description | 1757 G1 participants (14%) linked to at least one police record for a charge, offence 'taken into consideration', caution, or another out of court disposal. |
Type Of Material | Database/Collection of data |
Year Produced | 2022 |
Provided To Others? | Yes |
Impact | Facilitates ressearch into criminal activity without relying on self report. |
URL | https://doi.org/10.12688/wellcomeopenres.18720.1 |
Title | Bristol region NOx modelled Air Pollution Dataset |
Description | NOx air pollution data was modelled for the ALSPAC catchment area from 1990 to 2018. In conjunction with ALSPAC participant residential and school geocoding database this enables air pollution data exposure to be estimated and linked to participants. Using the ALGAE software ALSPAC can estimate the exposure with critical development periods (e.g. pregnancy trimesters). Directly measured air pollution records have been collected (from local authority deployed air pollution sensors) and these sensor data will be used to calibrate the modelled data. |
Type Of Material | Database/Collection of data |
Year Produced | 2018 |
Provided To Others? | Yes |
Impact | The data will be used in an ALSPAC based epidemiological assessment of the impact of in utero NOx exposure and lung-function outcomes. It is also being shared with collaborators at Imperial (London) for use in an assessment of the impact of availability of greenspace on mental health outcomes. |
Title | Broad Whole Exome sequencing |
Description | n=3000 to be released in 2024 |
Type Of Material | Database/Collection of data |
Year Produced | 2024 |
Provided To Others? | No |
Impact | none yet |
Title | Browser for the UK10K whole genome sequencing project |
Description | This work represents the need for a way to present both whole genome sequence data and the results obtained from the analysis of those data (for phenotypic associations in principle). This browser is an existing solution to the need to display genomewide results for sequencing data. |
Type Of Material | Database/Collection of data |
Provided To Others? | No |
Impact | This work has been published: Bioinformatics. 2015 Dec 15;31(24):4029-31. doi: 10.1093/bioinformatics/btv491. Epub 2015 Aug 26. An interactive genome browser of association results from the UK10K cohorts project. Geihs M1, Yan Y1, Walter K1, Huang J1, Memari Y1, Min JL2, Mead D1; UK10K Consortium, Hubbard TJ3, Timpson NJ2, Down TA4, Soranzo N5. |
Title | CLOSER harmonised BMI dataset |
Description | ALSPAC has contributed to a harmonised dataset through CLOSER which has harmonised data on height, weight and BMI at ages 7, 8, 9, 10, 11 and 17. The data has been lodged with the UK Data Service and can be accessed through a Special License |
Type Of Material | Database/Collection of data |
Year Produced | 2017 |
Provided To Others? | Yes |
Impact | Has contributed to our understanding of how rates of obesity have changed over the generations and the impact of social inequalities. See here: https://www.closer.ac.uk/research-fund-2/data-harmonisation/harmonising-measures-body-size-body-composition/ for a summary. |
URL | http://doi.org/10.5255/UKDA-SN-8208-1 |
Title | COVID Questionnaire 1 G0 and G1 dataset |
Description | Dataset containing Q1 results for G1 and G0 |
Type Of Material | Database/Collection of data |
Year Produced | 2020 |
Provided To Others? | Yes |
Impact | Contribution to our understanding of the impact of the pandemic, particularly mental health |
URL | https://wellcomeopenresearch.org/articles/5-127 |
Title | COVID Questionnaire 3 and serology results on G0 and G1 |
Description | Dataset containing Q3 results and results for home antibody testing for G1 and G0 |
Type Of Material | Database/Collection of data |
Year Produced | 2020 |
Provided To Others? | Yes |
Impact | Contribution to our understanding of the impact of the pandemic, based for identifying cases for further study on recuperation and longevity of infection. A data note has just been submitted to Wellcome Open |
Title | COVID questionnaire 2 G0 and G1 dataset |
Description | Dataset containing Q2 results for G1 and G0 |
Type Of Material | Database/Collection of data |
Year Produced | 2020 |
Provided To Others? | Yes |
Impact | Contribution to our understanding of the impact of the pandemic, particularly mental health |
URL | https://wellcomeopenresearch.org/articles/5-210 |