The Avon Longitudinal Study of Parents and Children: An international resource for population genomics and lifecourse epidemiology. Core Programme Support 2011-2015 and Core programme support 2014-2019

Lead Research Organisation: The Wellcome Trust Ltd

Abstract

For over 20 years Children of the 90s (or ALSPAC) has charted the health of 14,500 parents and
children. Now in its third decade it has started to study the next generation, the children of the
Children of the 90s. The study is unequalled by other population studies because of the breadth
and depth of information it holds on participants from before birth over 20 years ago through to the
present day. It is internationally renowned and used by researchers worldwide. The data allow
researchers to study key periods of development, how certain conditions develop and change over
time and are passed (or not) from one generation to the next, and how health is affected by the
interplay between genes and other factors like smoking, where people live and the job they do.
Our goals are to ensure the resource remains sustainable and open to researchers to use, and
that participants remain engaged. We will continue to gather information from the original children
through clinical assessments, questionnaires and record linkage, and will be recruiting and
gathering data on the children of the children as well as merging genetic data and enhancing research in the exciting new field of epigenomics.

Technical Summary

The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective cohort study with
unprecedented scope and detail of information on thousands of people from before birth through
to early adulthood, on their parents and now on their children. It is an internationally valued
resource at the forefront of population-based research. ALSPAC allows the investigation of
developmental trajectories marking critical periods in human life, the genetic and epigenetic
factors contributing to health and disease and the environmental exposures which form the context
within which these processes act. As ALSPAC participants enter adulthood and start having
children, the study's potential to contribute to scientific discovery is expanding, giving a greater
capacity to explore links between current and future health and the intergenerational components
of health and disease. ALSPAC is unequivocally the richest open-access epidemiological resource
in the world. Our goals are to ensure that ALSPAC (i) is sustained, (ii) has participation maximised
and (iii) is enhanced. These goals will be delivered by follow-up of the original cohort through clinic
assessment, questionnaires and record linkage, data collection on their children, consolidation of
GWAS data on all participants and the development of epigenomics research.

Organisations

Publications

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Al Ali A (2014) A three-dimensional analysis of the effect of atopy on face shape. in European journal of orthodontics

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Al Ali A (2014) The influence of asthma on face shape: a three-dimensional study. in European journal of orthodontics

 
Title Creative Reactions 2018 
Description Creative Reactions is an art exhibition associated with the national Pint of Science festival. Approximately 20 researchers using ALSPAC data were paired with local Bristol artists who produced an artwork based upon their research. The exhibition was held from 11-22 May 2018. 
Type Of Art Artistic/Creative Exhibition 
Year Produced 2018 
Impact Artworks were viewed and seen by the general public as well as the scientific community. Local radio, online and print media covered the exhibition. 
URL https://pintofscience.co.uk/event/creative-reactions-bristol-launch
 
Title Researcher videos for social media & website 
Description A series of video interviews with researchers and collaborators using ALSPAC data. Designed to share the findings and nature of work conducted with a lay audience. 
Type Of Art Film/Video/Animation 
Year Produced 2018 
Impact Widening awareness of research impact among core audiences - public, participants, collaborators and charities/third parties. It also provides an opportunity for researchers to thank participants and engage them in future participation with the study. 
URL http://www.bristol.ac.uk/alspac/media/researcher-interviews/
 
Description ALSPAC information used in in 'Your Health Record Saves Lives' information booklet produced by UK Clinical Research Collaboration
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL http://www.nhs.uk/Conditions/Clinical-trials/Documents/Research1.pdf
 
Description ALSPAC obesity data cited in government's child obesity strategy
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL https://www.gov.uk/government/publications/childhood-obesity-a-plan-for-action
 
Description ALSPAC research on bullying and maltreatment cited in EHRC race report
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
URL https://www.equalityhumanrights.com/en/race-report-healing-divided-britain
 
Description ALSPAC research on eczema and genes featured in the National Eczema Society's Exchange magazine (159, March 2016)
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL http://www.eczema.org/products/154
 
Description ALSPAC research on premature babies quoted in Parliament by Stephen Hammond MP
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Citation in other policy documents
URL https://hansard.parliament.uk/commons/2016-10-10/debates/5032D3A8-AA55-4388-BCE2-DE2ACAB8CDCC/School...
 
Description ALSPAC used as example of best practice by Health and Social Care Information Centre
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL http://systems.hscic.gov.uk/infogov/codes/cop
 
Description Adjournment debate on fetal alcohol spectrum disorder
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
URL https://hansard.parliament.uk/Commons/2019-01-17/debates/19011751000002/FoetalAlcoholSpectrumDisorde...
 
Description Bullying research included in textbook
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact The research features in 'Bullying', a textbook in the 'Issues' series by Independence Educational Publishers http://www.independence.co.uk/. It is in a format that is accessible to all levels but is aimed primarily at the 16-18 age group. According to the publisher, the book is used in a wide variety of courses including GCSE, A-level and further education, as well as by public libraries, prison education providers, government agencies and professional health and social care bodies.
URL http://www.independence.co.uk/shop/family-and-relationships/issues/bullying
 
Description Bullying research included in textbook
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
Impact The research features in 'Bullying', a textbook in the 'Issues' series by Independence Educational Publishers http://www.independence.co.uk/. It is in a format that is accessible to all levels but is aimed primarily at the 16-18 age group. According to the publisher, the book is used in a wide variety of courses including GCSE, A-level and further education, as well as by public libraries, prison education providers, government agencies and professional health and social care bodies.
URL http://www.independence.co.uk/shop/family-and-relationships/issues/bullying
 
Description Change in Information Commissioner's Office code of practice guidance on data protection following the Data Protection Act 2018
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
Impact CLOSER work on the need for clearer and changed regulatory guidance regarding data retention (see Boyd et al. 2018, available from: https://wellcomeopenresearch.org/articles/3-112/v1) led to a change in official guidance from the Information Commissioner's Office (see https://ico.org.uk/for-organisations/guide-to-data-protection/guide-to-the-general-data-protection-regulation-gdpr/principles/storage-limitation/). This has the potential to help safeguard data which could be used as research resources of the future.
URL https://ico.org.uk/for-organisations/guide-to-data-protection/guide-to-the-general-data-protection-r...
 
Description Chapter on childhood asthma included in RCPCH air pollution report
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL https://www.rcplondon.ac.uk/projects/outputs/every-breath-we-take-lifelong-impact-air-pollution
 
Description Evidence included in Commons Health Select Committee report
Geographic Reach National 
Policy Influence Type Gave evidence to a government review
URL http://www.publications.parliament.uk/pa/cm201415/cmselect/cmhealth/845/845.pdf
 
Description Evidence that little time outdoors contributes to the development of myopia in middle childhood
Geographic Reach National 
Policy Influence Type Citation in clinical reviews
 
Description Findings of research on dyslexia and vision recommended by Dyslexia Action
Geographic Reach National 
Policy Influence Type Influenced training of practitioners or researchers
URL http://www.dyslexiaaction.org.uk/news/%E2%80%98dyslexia-and-sight-wider-view%E2%80%99-research-welco...
 
Description Guidance on iodine cited by Scientific Advisory Committee on Nutrition
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL https://www.gov.uk/government/publications/sacn-statement-on-iodine-and-health-2014
 
Description Leading joint academic-NHS review on methods to onward share linked NHS records
Geographic Reach Local/Municipal/Regional 
Policy Influence Type Participation in a advisory committee
Impact A joint piece of work between CLOSER (led by Andy Boyd & Alison Park) and NHS Digital (led by Garry Coleman & Estelle Spence) through the NHS Digital Research Advisory Group. The work included conducting a stakeholder needs analysis amongst the longitudinal studies community (two workshops held) and a report generated. The findings are leading to a clearer and more efficient mechanisms to maximise the research value of the secondary use of routine health records in order to develop and more effective and efficient NHS.
URL https://digital.nhs.uk/services/research-advisory-group
 
Description New evidence on vitamin D supplementation in pregnancy from research showing that vitamin D status in pregnancy not associated with offspring bone mineral content
Geographic Reach National 
Policy Influence Type Citation in clinical reviews
 
Description New guidance on alcohol in pregnancy endorsed by Dr Simon Newell (RCOP), James Nicholls (Alcohol Research UK) and Professor David Nutt, Imperial.
Geographic Reach Multiple continents/international 
Policy Influence Type Citation in other policy documents
 
Description New guidance on importance of iodine in pregnancy diet backed up by BDA factsheet http://www.bda.uk.com/foodfacts/Iodine.pdf
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL https://www.bda.uk.com/foodfacts/Iodine
 
Description Participation in All Party Parliamentary Group on Autism - building brighter futures for children with autism event (10 July 2018)
Geographic Reach National 
Policy Influence Type Participation in a advisory committee
 
Description Questionnaire, linkage and interview data inform BIS report
Geographic Reach National 
Policy Influence Type Citation in other policy documents
URL https://www.gov.uk/government/publications/progression-into-higher-education-for-disadvantaged-and-u...
 
Description Research on school outcomes for premature babies endorsed by Professor Sir Al Aynsley Green (first Children's Commissioner for England)
Geographic Reach National 
Policy Influence Type Citation in other policy documents
 
Description Submitted evidence to Commons Health Select committee inquiry into suicide prevention
Geographic Reach Multiple continents/international 
Policy Influence Type Gave evidence to a government review
URL http://data.parliament.uk/WrittenEvidence/CommitteeEvidence.svc/EvidenceDocument/Health/Suicide%20Pr...
 
Description Submitted evidence to Commons Health Select committee inquiry into suicide prevention
Geographic Reach Multiple continents/international 
Policy Influence Type Gave evidence to a government review
URL http://data.parliament.uk/WrittenEvidence/CommitteeEvidence.svc/EvidenceDocument/Health/Suicide%20Pr...
 
Description 37356: Scourfield fellowship: Fathers, social interventions and children's wellbeing
Amount £8,482 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 09/2011 
End 08/2014
 
Description 38361: The determinants of measures of immune function in a wild mammal.
Amount £5,000 (GBP)
Organisation Natural Environment Research Council 
Sector Public
Country United Kingdom
Start 07/2011 
End 01/2015
 
Description 43249: NICE childhood obesity weight management
Amount £2,250 (GBP)
Funding ID F00003186 
Organisation National Institute for Health and Care Excellence (NICE) 
Sector Public
Country United Kingdom
Start 04/2012 
End 03/2014
 
Description 43992: POPPIE Predictors of Persistence & Psychological Impact of Childhood Eczema
Amount £800 (GBP)
Funding ID F00022685 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 06/2012 
End 11/2012
 
Description 47297: B1227 Biomarker study
Amount £2,593 (GBP)
Organisation Royal College of Surgeons in Ireland 
Sector Learned Society
Country Ireland
Start 03/2013 
End 02/2017
 
Description 59452: C.Williams Senior Research Fellowship
Amount £37,043 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2015 
End 09/2020
 
Description A framework for linking and sharing social media data for high-resolution longitudinal measurement of mental health across CLOSER cohorts
Amount £149,971 (GBP)
Funding ID ES/R011583/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 03/2018 
End 02/2019
 
Description ALSPAC Questionnaire - dietary preference
Amount £10,000 (GBP)
Organisation University of Edinburgh 
Sector Academic/University
Country United Kingdom
Start 06/2017 
End 12/2017
 
Description Adolescent and adult mental health outcomes of autism and autistic traits
Amount £74,096 (GBP)
Funding ID TRUST/VC/AC/SG/3747-6849 
Organisation Baily Thomas Charitable Fund 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2016 
End 03/2018
 
Description Adolescent and adult mental health outcomes of autism and autistic traits
Amount £226,152 (GBP)
Funding ID MR/R004889/1 
Organisation Medical Research Council (MRC) 
Department Medical Research Foundation
Sector Charity/Non Profit
Country United Kingdom
Start 06/2017 
End 05/2019
 
Description Adverse life events, inflammation, and trajectories of emotional and behavioural problems in childhood
Amount £161,295 (GBP)
Funding ID ES/P001742/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 04/2017 
End 05/2018
 
Description An investigation of the causal pathways from childhood conduct problems to poor health outcomes and criminal behaviour in adulthood
Amount £250,000 (GBP)
Funding ID 209138/Z/17/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2018 
End 03/2022
 
Description Are sleep difficulties in ADHD an index of neurodevelopmental severity?
Amount £57,539 (GBP)
Funding ID 918-3021 
Organisation The Waterloo Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2017 
End 10/2020
 
Description Autism Speaks B954 RX9194 'Genetic Variation and Gene-Environment Influences in Autistic-like traits'
Amount £71,704 (GBP)
Funding ID 7132 
Organisation Autism Speaks 
Sector Charity/Non Profit
Country United States
Start 12/2011 
End 05/2014
 
Description B2390 Internal Locus of Control: Origins, Determinants, and Benefits
Amount £5,000 (GBP)
Funding ID 58223 
Organisation The John Templeton Foundation 
Sector Academic/University
Country United States
Start 09/2015 
 
Description BIOSHARE Social Core - Qualatative Study
Amount £1,806 (GBP)
Funding ID Health-F4-2010-261433 
Organisation European Commission 
Sector Public
Country European Union (EU)
Start 07/2014 
End 01/2015
 
Description Behavioural and neurophysiological effects of schizophrenia risk genes
Amount £789,477 (GBP)
Funding ID MR/K004360/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description CLOSER AMENDMENT 4: CLOSER INNOVATION FUND
Amount £112,678 (GBP)
Organisation Economic and Social Research Council 
Department ESRC Seminar Series
Sector Academic/University
Country United Kingdom
Start  
End 09/2017
 
Description CLOSER Amendment 1: Cohort and Longitudinal Studies Enhancement Resources Grant
Amount £327,143 (GBP)
Organisation Economic and Social Research Council 
Department ESRC Seminar Series
Sector Academic/University
Country United Kingdom
Start  
End 09/2019
 
Description CLOSER Amendment 3: Cohort and longitudinal studies enhancement resources grant
Amount £149,136 (GBP)
Organisation Economic and Social Research Council 
Department ESRC Seminar Series
Sector Academic/University
Country United Kingdom
Start  
End 09/2019
 
Description CLOSER Amendment 5: Innovation Fund - Occupational and social class data coding and harmonisation
Amount £9,811 (GBP)
Funding ID ES/K000357/1 
Organisation Economic and Social Research Council 
Department ESRC Seminar Series
Sector Academic/University
Country United Kingdom
Start 01/2016 
End 08/2017
 
Description CLOSER Ammendment 2: Cohort and longitudinal studies enhancement resources
Amount £95,684 (GBP)
Organisation Economic and Social Research Council 
Department ESRC Seminar Series
Sector Academic/University
Country United Kingdom
Start  
End 09/2017
 
Description Can Hip DXA scans be used to identify genetic determinants of hip shape & osteoarthritis? Proposal for a proof-of-concept study B1372
Amount £11,429 (GBP)
Funding ID 20244 
Organisation Versus Arthritis 
Start 02/2013 
End 01/2016
 
Description Characterising brain network differences during scene perception and memory in young adult APOE-e4 carriers: multi-modal imaging in ALSPAC
Amount £1,420,574 (GBP)
Funding ID MR/N01233X/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2016 
End 04/2020
 
Description Childhood predictors of inadequate health literacy in young adults
Amount £28,568 (GBP)
Organisation Sir Halley Stewart Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2017 
End 02/2019
 
Description Cohorts as Platforms for Mental Health research (CaP:MH)
Amount £1,497,192 (GBP)
Funding ID MC_PC_17210 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2018 
End 03/2020
 
Description Cohorts as Platforms for Mental Health research (MRC MH Pathfinder)
Amount £1,497,192 (GBP)
Funding ID MC_PC_17210 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2018 
End 03/2020
 
Description Consortium on Vulnerability to Externalizing Disorders and Addictions (c-VEDA)
Amount £1,190,293 (GBP)
Funding ID MR/N000390/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2015 
End 09/2018
 
Description Creating a West African BioResource for Nutritional Genetics and Epigenetics
Amount £186,171 (GBP)
Funding ID MC_PC_MR/R020183/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2018 
End 12/2018
 
Description Creating a West African BioResource for Nutritional Genetics and Epigenetics
Amount £186,171 (GBP)
Funding ID MC_PC_MR/R020183/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2018 
End 02/2019
 
Description Cytoprotective defence mechanisms during tissue maintenance and repair - Helen Weaver
Amount £1,159,829 (GBP)
Funding ID 208762/Z/17/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2018 
End 07/2023
 
Description Deriving and validating a clinical prediction rule for the diagnosis of asthma in primary care
Amount £207,554 (GBP)
Funding ID CAF/17/01 
Organisation Chief Scientist Office 
Sector Public
Country United Kingdom
Start 09/2017 
End 06/2021
 
Description Describing habitual levels of physical activity (PA) in older people in terms of impact loads and how this relates to bone and other systems
Amount £58,433 (GBP)
Funding ID MR/K024973/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 07/2013 
End 06/2016
 
Description Development of ALSPAC Industry Partner and Participant Portal
Amount £15,000 (GBP)
Organisation University of Bristol 
Sector Academic/University
Country United Kingdom
Start 03/2018 
End 08/2018
 
Description Development of ALSPAC Industry Partner and Participant Portal (Timpson NJ, Skinner A.)
Amount £15,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 05/2018 
End 05/2019
 
Description Do epigenetic markers contribute to the excess risk of diabetes and coronary heart disease in Indian Asians?
Amount £196,086 (GBP)
Funding ID 082464/Z/07/C 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description Does epigenetic methylation explain the gender-switch in adolescent asthma?
Amount $153,747 (USD)
Funding ID 1R01A/121226-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 01/2016 
End 12/2016
 
Description Early life adversity and life course health: an investigation of adversity clustering and associations with health
Amount £232,283 (GBP)
Funding ID ES/P010229/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 01/2018 
End 12/2020
 
Description Eating Behaviour Measurement using the Mandometer - A Pilot Study In ALSPAC B1038
Amount £600 (GBP)
Organisation National Institute for Health Research 
Department NIHR Biomedical Research Centre
Sector Academic/University
Country United Kingdom
Start 01/2012 
End 12/2012
 
Description Effect of different feeding methods and non-nutritive sucking behaviours on child speech development
Amount £52,438 (GBP)
Funding ID ICA-CDRF-2016-02-053 
Organisation National Institute for Health Research 
Sector Public
Country United Kingdom
Start 04/2017 
End 03/2021
 
Description Electronic Longitudinal Alcohol Study in Communities (ELAStiC)
Amount £978,102 (GBP)
Funding ID ES/L015471/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 10/2016 
End 09/2019
 
Description Enhancing Environmental data Resources in Cohort Studies: ALSPAC exemplar (ERICA)
Amount £99,899 (GBP)
Funding ID NE/P010830/1 
Organisation Natural Environment Research Council 
Sector Public
Country United Kingdom
Start 02/2017 
End 01/2018
 
Description Environmental risk factors of health-risk behaviours: Using DNA to strenghten causal inference
Amount £225,000 (GBP)
Organisation MQ Transforming Mental Health 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2017 
End 01/2020
 
Description Epidemiological studies of human transgenerational responses (TGR) to paternal and ancestral exposures
Amount $25,000 (USD)
Funding ID 2016-165617 
Organisation Silicon Valley Community Foundation 
Sector Charity/Non Profit
Country United States
Start 01/2017 
End 12/2017
 
Description Ethical aspects of epidemiological research on young people involving linkage to routine individual data B1089
Amount £860 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2012 
End 10/2012
 
Description Excessive drinking and alcohol related harms in Adulthood: ALSPAC at 24
Amount £1,378,535 (GBP)
Funding ID MR/L022206/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 06/2015 
End 05/2019
 
Description Fellowship B1088 SSCM.RJ5562 'Molecular and life-course aspects of APOE and TOMM40 in cognition'
Amount £35,305 (GBP)
Funding ID WT096114/Z/11/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2012 
End 12/2015
 
Description Fellowship Bath B1423 SSCM.RD1832 ' Iodine status in pregnancy & child neurodevelopment'
Amount £11,707 (GBP)
Funding ID MR/K02132X/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 06/2013 
End 05/2016
 
Description Gene-Environment Interplay in the Comorbity of PTSD and Disordered Eating
Amount £10,909 (GBP)
Organisation National Institutes of Health Clinical Center 
Sector Hospitals
Country United States
Start 01/2013 
End 12/2016
 
Description Genetic, behavioural and cognitive mechanisms underpinning the association between mother and offspring mental health problems: mental health intergenerational transmission (MHINT)
Amount € 1,499,611 (EUR)
Funding ID 758813 
Organisation European Research Council (ERC) 
Sector Public
Country European Union (EU)
Start 12/2017 
End 11/2022
 
Description Genetics of wound healing - BCG scar study
Amount £46,467 (GBP)
Organisation University of Bristol 
Department Elizabeth Blackwell Institute for Health Research
Sector Academic/University
Country United Kingdom
Start 11/2016 
End 08/2017
 
Description HDHL-Biomarkers: Early life programming of childhood health: a nutritional and epigenetic investigation (ALPHABET)
Amount £101,222 (GBP)
Funding ID BB/P028187/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 04/2017 
End 09/2019
 
Description How early stress gets under the skin: The role of DNA methylation in the development of youth conduct problems and comorbid symptoms
Amount £250,543 (GBP)
Funding ID ES/N001273/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 01/2016 
End 12/2018
 
Description Informing educational interventions using genome-wide data: causal evidence from 573,586 participants of eight cohort studies
Amount £222,571 (GBP)
Funding ID ES/N000757/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 01/2016 
End 12/2018
 
Description Interplay between Peer-based Processes and Alcohol Metabolism Genes on Trajectories of Alcohol Use across Adolescence
Amount $68,657 (USD)
Funding ID 1F31AA025833-01 
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 04/2017 
End 03/2019
 
Description Investigating the Epidemiology of CFS/ME in children using the ALSPAC cohort B1425 RD1805
Amount £21,391 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2013 
End 09/2015
 
Description Investigation of the causal effects of atopic eczema on other health outcomes
Amount £89,968 (GBP)
Organisation British Skin Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start 11/2016 
End 10/2018
 
Description Ipsos Mori: Qualitative research on attitudes around commercial access to health, biomedical and genetic data
Amount £2,195 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2015 
End 11/2015
 
Description Klarman Family Foundation B1190 'Epigentics of Eating Disorders : A Lifespan Approach'
Amount $132,590 (USD)
Organisation The Klarman Family Foundation 
Sector Charity/Non Profit
Country United States
Start 06/2012 
End 05/2014
 
Description LONGITUDINAL ADMINISTRATIVE DATA SPINE SCOPING PROJECT GRANT FOR THE SPF UK POPULATION LAB WAVE I
Amount £236,901 (GBP)
Funding ID ES/S016732/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 12/2018 
End 03/2019
 
Description Life course aetiology of dementia and cognitive decline: improving causal inference
Amount £315,800 (GBP)
Funding ID MR/P014437/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 03/2017 
End 02/2020
 
Description Lifecourse epidemiology of female reproductive health and its relation to chronic disease
Amount £70,205 (GBP)
Funding ID MR/M009351/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 12/2014 
End 11/2019
 
Description MRC Mental Health Pathfinder Award
Amount £1,400,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2018 
End 04/2020
 
Description MRC Proximity to Discovery Industry Engagement Fund: Development of ALSPAC Industry Partner and Participant Portal
Amount £15,000 (GBP)
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2018 
End 09/2018
 
Description Mapping Neurodevelopmental Trajectories for Adult Psychiatric Disorder: ALSPAC-MRI-II
Amount £1,791,731 (GBP)
Funding ID MR/S003436/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 12/2018 
End 11/2022
 
Description Mapping phenotypic to genetic variability in the High Bone Mass Study
Amount £355,425 (GBP)
Funding ID 20000 
Organisation Versus Arthritis 
Start 01/2013 
End 12/2018
 
Description Mental health and educational achievement in UK adolescents
Amount £131,721 (GBP)
Funding ID ES/P00881X/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 07/2017 
End 12/2018
 
Description Mitochondrial DNA copy number as a phenotypic trait for human diseases in genetic epidemiological studies
Amount £384,038 (GBP)
Funding ID MR/K002767/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Molecular, Genetic and Lifecourse Epidemiology - PhD programme (original programme funding and extension - awarded in 2015, extended by one year in 2017)
Amount £1,820,000 (GBP)
Funding ID 108902/Z/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2016 
End 10/2024
 
Description Multidimensional Phenotyping in Eczema
Amount £89,991 (GBP)
Organisation British Skin Foundation 
Sector Charity/Non Profit
Country United Kingdom
Start  
 
Description NMHB Research Grant SSCM.RD1796 'Behavioral & neurophysicological effects of schizophrenia risk genes'
Amount £112,078 (GBP)
Funding ID MR/K004360/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2013 
End 03/2017
 
Description Neurodevelopmental disorders: What happens when children grow up and why?
Amount £893,353 (GBP)
Funding ID 204895/Z/16/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 02/2017 
End 01/2021
 
Description Non-genetic inheritance in human development
Amount £995,516 (GBP)
Funding ID ID#60828 
Organisation The John Templeton Foundation 
Sector Academic/University
Country United States
Start 01/2018 
End 09/2020
 
Description Novel epidemiological methods to infer the causal effects of risk factors on neuropsychiatric and cardiovascular disorders
Amount $358,957 (AUD)
Funding ID APP1079583 
Organisation National Health and Medical Research Council 
Sector Public
Country Australia
Start 01/2015 
End 12/2017
 
Description Our Menopauses: an event for sharing experiences and information about menopause in Bristol
Amount £2,619 (GBP)
Organisation University of Bristol 
Department Elizabeth Blackwell Institute for Health Research
Sector Academic/University
Country United Kingdom
Start 06/2017 
End 11/2017
 
Description Oxytocin-Related Predictors of Postpartum Maternal Mood and Mothering B1167
Amount £4,628 (GBP)
Organisation National Institutes of Health Clinical Center 
Sector Hospitals
Country United States
Start 04/2012 
End 03/2014
 
Description PAR-13-109 Mechanistic Insights from Birth Cohorts (R01)
Amount £110,613 (GBP)
Organisation National Institutes of Health (NIH) 
Sector Public
Country United States
Start 09/2014 
End 08/2019
 
Description Pathways to peak lung function: Genetic, Environmental and lifestyle influences on maximally attainable lung function in young adults
Amount £482,295 (GBP)
Funding ID MR/M022501/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 05/2015 
End 08/2018
 
Description Pathways to psychosis: investigating environmental, cognitive and genetic mechanisms underlying development of psychotic experiences in young adults
Amount £455,151 (GBP)
Funding ID MR/M006727/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 06/2014 
End 06/2018
 
Description PhD Studentship - B910 SSCM.RJ5158 'Biological Differences in Smoking Behaviour'
Amount £38,715 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2012 
End 06/2012
 
Description Picky Eating in the ALSPAC cohort: Determinants and related health outcomes
Amount £1,230 (GBP)
Organisation Nestlé Research Center 
Sector Private
Country Switzerland
Start 05/2014 
End 03/2016
 
Description Population Research Committee - Project Award B911 SSCM.RJ5681'Breast tissue composition in young women and its pre-natal and early life determinant: a study nested within the ALSPAC'
Amount £90,345 (GBP)
Funding ID C405/A12730 
Organisation Cancer Research UK 
Sector Charity/Non Profit
Country United Kingdom
Start 09/2011 
End 12/2012
 
Description Predictors and consequences of being a Child in Need or Looked After: data linkage study based on ALSPAC
Amount £50,931 (GBP)
Organisation University of Bristol 
Department Elizabeth Blackwell Institute for Health Research
Sector Academic/University
Country United Kingdom
Start 10/2016 
End 09/2018
 
Description Programme B798 SSCM.RJ5447 'The relationship of the menopausal transition to healthy aging and chronic disease risk'
Amount £774,825 (GBP)
Funding ID 092830/Z/10/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2011 
End 06/2016
 
Description Psychosocial factors and cancer incidence: a pre-planned meta-analysis of the Psychosocial factors and Cancer
Amount € 1,328,435 (EUR)
Funding ID VU 20l7-8288 
Organisation Dutch Cancer Society (KWF) 
Sector Learned Society
Country Netherlands
Start 04/2018 
End 09/2021
 
Description Psychosocial resilience in children of mothers with depression B1112
Amount £702 (GBP)
Funding ID ES/J011657/1 
Organisation Economic and Social Research Council 
Department ESRC Seminar Series
Sector Academic/University
Country United Kingdom
Start 10/2012 
End 09/2014
 
Description Publication Metadata Augmentation
Amount £112,678 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 01/2016 
End 11/2017
 
Description Pulmonary epithelial barrier and immunological functions at birth and in early life - key determinants of the development of asthma?
Amount £2,560,571 (GBP)
Funding ID 108818/Z/15/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2016 
End 12/2018
 
Description Research - B1173 SSCM.RD1795 'Study Team for early life Asthma Research (STELAR)
Amount £38,406 (GBP)
Funding ID MR/K002449/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 01/2013 
End 12/2016
 
Description Research B998 SSCM.RD1782Cussens 'A graphical model approach to pedigree construction using constrained optimisation'
Amount £4,602 (GBP)
Funding ID G1002312 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2011 
End 10/2014
 
Description Research Grant - B836 SSCM.RK7212 'Maternal thyroid status and offspring development'.
Amount £14,529 (GBP)
Funding ID ETM/97 
Organisation Chief Scientist Office 
Sector Public
Country United Kingdom
Start 04/2011 
End 03/2013
 
Description Research Grant BBR Scheme (BBSRC)- B1074 SSCM.RA0543 'A multigenerational prospective resource for integrating genetic, epigenetic and dense phenotypic measures from birth to 18.'
Amount £1,186,455 (GBP)
Funding ID BB/I025751/1 
Organisation Biotechnology and Biological Sciences Research Council (BBSRC) 
Sector Public
Country United Kingdom
Start 09/2011 
End 08/2013
 
Description RoSPA: Evaluation of Lifeskills using the ALSPAC Cohort - LASER Safety Education Schemes
Amount £19,733 (GBP)
Organisation Royal Society for the Prevention of Accidents 
Sector Charity/Non Profit
Country United Kingdom
Start 01/2014 
End 10/2014
 
Description S1P1R genetic profiles in endothelial function and disease
Amount € 204,537 (EUR)
Funding ID 166002 - CW388001 
Organisation Sanofi 
Department Sanofi Research Division
Sector Private
Country France
Start 03/2016 
End 07/2019
 
Description Seeing is believing in ALSPAC
Amount £199,387 (GBP)
Funding ID 102215/Z/13/B 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2016 
End 10/2016
 
Description Seventh Framework Programme - B1301 SSCM.RQ8840 'Collaborative Projects & Networks of Excellence EXPOsOMICS'
Amount € 56,704 (EUR)
Funding ID 308610 
Organisation European Commission 
Department Seventh Framework Programme (FP7)
Sector Public
Country European Union (EU)
Start 10/2012 
End 09/2016
 
Description Study of Emerging Adulthood and Cardiomatic Health in ALSPAC: The Influence and of growth and other exposures
Amount £999,049 (GBP)
Funding ID CS/15/6/31468 
Organisation British Heart Foundation (BHF) 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2015 
End 06/2020
 
Description TENOVUS - Da Silva Focus Group
Amount £804 (GBP)
Organisation University of Dundee 
Sector Academic/University
Country United Kingdom
Start 10/2015 
End 11/2015
 
Description Testing evolutionary hypotheses of social development in the ALSPAC cohort
Amount £1,559 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2014 
End 09/2015
 
Description Testing the feasibility and user acceptability of integrating wearable air pollution monitors into population based studies
Amount £24,769 (GBP)
Organisation University of Bristol 
Department Elizabeth Blackwell Institute for Health Research
Sector Academic/University
Country United Kingdom
Start 07/2016 
End 08/2017
 
Description The Avon Longitudinal Study for Parents and Children: An international resource for population genomic and lifecourse epidemiology. Core programme support 2014-2019
Amount £7,903,667 (GBP)
Funding ID 102215/Z/13/Z 
Organisation Wellcome Trust 
Department Wellcome - MRC Cambridge Stem Cell Institute
Sector Academic/University
Country United Kingdom
Start 04/2014 
End 03/2019
 
Description The Genetic Basis of Urinary Incontinence in Women B956
Amount £44,664 (GBP)
Organisation International Urogynecological Association (IUGA) 
Sector Learned Society
Country Global
Start 10/2011 
End 09/2014
 
Description The Millennium Cohort Study Sweep 6 (Age 14) Survey (GWAS data collection).
Amount £1,000,000 (GBP)
Organisation ESRC Impact Acceleration Account Cambridge 
Sector Academic/University
Country United Kingdom
Start 02/2018 
End 02/2019
 
Description The Millennium Cohort Study Sweep 6 (Age 14) Survey - extension (GWAS data collection and analysis)
Amount £1,052,503 (GBP)
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 01/2017 
End 03/2018
 
Description The causal map of the human phenome
Amount £809,240 (GBP)
Funding ID 208806 
Organisation Sir Henry Dale Fellowships 
Sector Charity/Non Profit
Country United Kingdom
Start 04/2018 
End 03/2023
 
Description The developmental role of metabolism, appetite and growth in eating disorders: exploring novel longitudinal risk pathways
Amount £215,430 (GBP)
Funding ID MR/R004803/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 07/2017 
End 09/2020
 
Description The genetic epidemiology of High Bone Mass: skeletal geometry, turnover and fat metabolism, and implications for the wider population
Amount £3,322 (GBP)
Organisation Versus Arthritis 
Start 01/2013 
End 01/2018
 
Description Type 2 Diabetes and Cancer: RD Lawrence Fellowship - Emma Vincent
Amount £587,237 (GBP)
Funding ID 17/0005587 
Organisation Diabetes UK 
Sector Charity/Non Profit
Country United Kingdom
Start 10/2017 
End 09/2022
 
Description UK Department for Business Innovation & Skills (BIS) B931 RK7220 'Further education data linkage projects'
Amount £55,000 (GBP)
Funding ID BIS/RBU/008/2011 
Organisation Department for Business, Energy & Industrial Strategy 
Sector Public
Country United Kingdom
Start 02/2011 
End 12/2012
 
Description UK Dept for Business Innovation and Skills B2057 SSCM.RK 'Data Linkage Proposal 2013'
Amount £30,000 (GBP)
Funding ID BIS/RBU/011/2013 
Organisation Department for Business, Energy & Industrial Strategy 
Sector Public
Country United Kingdom
Start 10/2013 
End 09/2015
 
Description UK MenCar4
Amount £4,483 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2015 
End 09/2015
 
Description Understanding Asthma Phenotypes
Amount £181,852 (GBP)
Funding ID 668954 
Organisation European Research Council (ERC) 
Sector Public
Country European Union (EU)
Start 01/2016 
End 12/2020
 
Description Understanding successful progression to higher education for the white working class and minority ethnic groups (B2215)
Amount £14,081 (GBP)
Organisation Department for Business, Energy & Industrial Strategy 
Sector Public
Country United Kingdom
Start 02/2014 
End 07/2015
 
Description Understanding the Antecedents and Outcomes of Frequent Adolescent Cannabis Use
Amount £250,000 (GBP)
Funding ID 209158 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 05/2018 
End 05/2022
 
Description Unique research opportunities in the genetics and epidemiology of disordered gambling
Amount $396,559 (USD)
Organisation National Center for Responsible Gaming 
Start 07/2017 
End 06/2020
 
Description Using Mendelian Randomisation to Establish the Causal Role of Cigarette Smoking in Anxiety and Depression
Amount £110,594 (GBP)
Funding ID MR/J01351X/1 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start  
 
Description Using birth cohorts to understand the impact of urban green space on child health and wellbeing
Amount £79,929 (GBP)
Funding ID 2081026 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 10/2018 
End 03/2022
 
Description Using genetic and environmental risks to understand variation in social emotional, and educational outcomes in individuals with language impairments
Amount £161,348 (GBP)
Funding ID ES/P001955/1 
Organisation Economic and Social Research Council 
Sector Public
Country United Kingdom
Start 04/2017 
End 09/2019
 
Description Using linked electronic health data to improve eczema diagnosis and outcomes
Amount £1,305,851 (GBP)
Funding ID 205039/Z/16/Z 
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 03/2017 
End 02/2019
 
Description WT Biomedical Resource - B1234 SSCM.RD1793 'The 1958 Birth Cohort Biomedical Resource - facilitating access to data and samples and enhancing future utility'
Amount £668,124 (GBP)
Funding ID G1001799 
Organisation Medical Research Council (MRC) 
Sector Academic/University
Country United Kingdom
Start 04/2011 
End 12/2014
 
Description WT Project award - B1118 'Dopamine Function, Cognitive Flexibility and Emotion Regulation'
Amount £4,816 (GBP)
Organisation Wellcome Trust 
Sector Charity/Non Profit
Country United Kingdom
Start 07/2011 
End 01/2012
 
Title Data Access Agreement (DAA) data sharing contract 
Description The data access agreement is a new data sharing contract which is compatible with contemporary legislative (e.g. General Data Protection Regulations) and research governance expectations. It aligns with ALSPAC's Online Proposal System for efficient generation of specified and controlled data requests. Importantly, the DAA enables the replication of third-party data owner requirements and the addition of particular governance controls for specific datasets (e.g. geo-spatial datasets), and as such is an important element in ALSPAC's process to allow onward sharing of linked health, geo-spatial and social records. 
Type Of Material Improvements to research infrastructure 
Year Produced 2018 
Provided To Others? Yes  
Impact The DAA is a central component in ALSPAC's negotiations with NHS Digital to enable onward sharing of linked records. 
URL http://www.bristol.ac.uk/alspac/researchers/access/
 
Title Data Privacy Impact Assessment Process 
Description A new privacy assessment tool for ALSPAC which enables the assessment of data flows (i.e. new record linkages or new data sharing with research users) in line with EU General Data Protection Regulation requirements. The tool allows the assessment of diverse risks and particular research scenarios (e.g. the use of geocoded data in the research process, the additional sensitivities of using mental or sexual health records in research investigations. 
Type Of Material Improvements to research infrastructure 
Year Produced 2018 
Provided To Others? No  
Impact Ensuring ALSPAC data sharing is legally compliant. 
 
Title Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference 
Description Detailed phenotyping is required to deepen our understanding of the biological mechanisms behind genetic associations. In addition, the impact of potentially modifiable risk factors on disease requires analytical frameworks that allow causal inference. We have described the characteristics of Recall-by-Genotype (RbG) as a study design aimed at addressing both these needs. We have considered the efficacy and practicality of the RbG approach, provide a catalogue of UK-based resources for such studies and present an online RbG study planner. 
Type Of Material Improvements to research infrastructure 
Year Produced 2017 
Provided To Others? Yes  
Impact Recent development. notably described here: https://www.nature.com/articles/s41467-018-03109-y - with related software - see the link below. 
URL http://www.bristol.ac.uk/integrative-epidemiology/faciliitiesresources/software/
 
Title Implementation of DataSHIELD for the InterConnect project 
Description Prof Paul Burton worked with Professor Nick Wareham's MRC-Epidemiology Unit led, Interconnect Project which is funded by the European Union to implement DataSHIELD on a consortium of eight cohorts/biobanks (seven European, one North American) including ALSPAC. This required a standard implementation of the DataSHIELD structure for remote federated analysis of "horizontally partitioned" data (different sources hold the same variables on different individuals). 
Type Of Material Improvements to research infrastructure 
Year Produced 2017 
Provided To Others? Yes  
Impact The implementation of DataSHIELD has been successfully led by Tom Bishop who is the lead DataSHIELD development team member based in Cambridge. Prof Burton's team have provided ongoing support of both the technology and statistical methods. This work was successful and a paper is currently under review at the International Journal of Epidemiology: 
URL http://www.interconnect-diabetes.eu/
 
Title Improved access policy 
Description A much improved Access Policy has been written and made available via the website 
Type Of Material Improvements to research infrastructure 
Year Produced 2014 
Provided To Others? Yes  
Impact Ensures rules regarding data access are clear and transparent 
URL http://www.bristol.ac.uk/alspac/researchers/data-access/
 
Title Imputed Genome Wide (GWAS) single nucleotide polymorhism (SNP) dataset 
Description Imputation of 526,688 SNPs post quality control to the HapMap CEU population, release 22 for subjects in ALSPAC with GWAS data. 
Type Of Material Biological samples 
Year Produced 2013 
Provided To Others? Yes  
Impact The data have been used in several high impact publications including: Anttila, V. et al. 2013. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nat Genet. 2013 Aug;45(8):912-7 Hinds, D.A. et al. (In press). A meta-analysis of self-reported allergy identifes shared and allergy-specifc susceptibility loci Nat Genet. 2013 Aug;45(8):907-11 Evans, D.M. et al. 2013. Genome-Wide Association Study Identifies Loci Affecting Blood Copper, Selenium and Zinc. Hum Mol Genet. 2013 Oct 1;22(19):3998-4006 
 
Title Introduction of REDCap as a data collection tool 
Description REDCap has been successfuly introduced as the data collection tool used in clinic based data collection. It is also about to be used for the first time for online questionnaire data collection 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact Streamlines data collection; minimising errors 
URL http://www.project-redcap.org/
 
Title Introduction of cost recovery, replacing data buddy fee 
Description At the request of the funders a number of salaries related to data provision are now recovered directly from external researchers who pay a variable amount (depending on the amount and type of data) to access ALSPAC data 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact Cost recovery income is monitored very closely - currently the model is not bringing in sufficient income. It will be reassessed at the end of year 1. 
 
Title Metadata: Variable catalogue 
Description Improved metadata provision - a simple list of variables available so that researchers can simply copy and paste in order to provide lists of variables as part of their data request under cost recovery 
Type Of Material Improvements to research infrastructure 
Year Produced 2014 
Provided To Others? Yes  
Impact Improves accessibility/discoverability of data 
URL http://www.bristol.ac.uk/alspac/researchers/data-access/data-dictionary/
 
Title Online booking system 
Description Bespoke software development allowing study participants to book appointments online to attend the clinical assessment 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact Improved participant experience 
 
Title Online proposal for data access system 
Description Bespoke software development where researchers can enter details of new proposals to access ALSPAC data, system processes these and logs all relevant supporting information and agreements together (see https://proposals.epi.bristol.ac.uk/) 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact Improved system providing speedier access to ALSPAC data. We have been approached by other research groups interested in using this system and we are exploring options around how we might make this available to others. 
URL https://proposals.epi.bristol.ac.uk/
 
Title Online questionnaire system 
Description Successful development of an effective online questionnaire system used by participants to complete ALSPAC questionnaires via the study website 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact More efficient and cost effective collection of data from research particpants 
 
Title Protocol for genetic annotation and characterization 
Description We have developed a tool which annotates all genetic variants within a user specified region of the human genome. These annotations are collated from various databases, including information such as (but not limited to) predicted consequence, predicted deleterious impact, trait associations, quantitative trait loci (i.e. expression, methylation, chromatin, metabolomics, proteomics), regulatory information, biological pathways and druggable/trials info. 
Type Of Material Model of mechanisms or symptoms - in vitro 
Provided To Others? No  
Impact As the tool is unreleased there has been no impact yet. However, we intend to share the tool with the French pharmaceutical company Sanofi once it is ready as part of our on-going collaboration. 
 
Title Providing a genomic teaching resource 
Description Teaching the methods and approaches used in genetic epidemiology is most effective when realistic data is available for students to use. We have scrambled the ALSPAC genetic data in order to preserve the genetic characteristics of the dataset whilst making the data non-disclosive of the participants. 
Type Of Material Improvements to research infrastructure 
Provided To Others? No  
Impact This scrambled dataset has been used in at least six short courses on genetic epidemiology to date, and is continually used to teach students. 
 
Title Statistical methods for approaching lifecourse methods 
Description A number of groups are working on methods for analysing longitudinal data from the study producing both novel methods and building on existing methods to make best use of the repeat measures ALSPAC has. This area of work has a particular focus on lifecourse models. 
Type Of Material Improvements to research infrastructure 
Year Produced 2015 
Provided To Others? Yes  
Impact A number of papers have been published including: Smith AD, Hardy R, Heron J, Joinson CJ, Lawlor DA, Macdonald-Wallis C, Tilling K. A structured approach to hypotheses involving continuous exposures over the life course. Int J Epidemiol. 2016 Aug;45(4):1271-1279. Epub 2016 Jul 1. Howe LD, Smith AD, Macdonald-Wallis C, Anderson EL, Galobardes B, Lawlor DA, Ben-Shlomo Y, Hardy R, Cooper R, Tilling K, Fraser A. Relationship between mediation analysis and the structured life course approach. Int J Epidemiol. 2016 Aug;45(4):1280-1294. Epub 2016 Sep 27. Smith AD, Heron J, Mishra G, Gilthorpe MS, 
 
Title Statistical methods for dealing with repeat measures 
Description A number of groups are working on methods for analysing longitudinal data from the study producing both novel methods and building on existing methods to make best use of the repeat measures ALSPAC has. This covers a variety of different types of data and areas of research including growth, risky behaviours, diet and health outcomes 
Type Of Material Improvements to research infrastructure 
Year Produced 2010 
Provided To Others? Yes  
Impact A number of papers have been published. A few relevant examples are provided below: Anderson EL, Tilling K, Fraser A, Macdonald-Wallis C, Emmett P, Cribb V, Northstone K, Lawlor DA, Howe LD. Estimating Trajectories of Energy Intake Through Childhood and Adolescence Using Linear-Spline Multilevel Models. Epidemiology. Epub 2013 May 21. PMID: 23698751 Howe LD, Tilling K, Galobardes B, Davey Smith G, Gunnell D, Lawlor DA. Socioeconomic differences in childhood growth trajectories: at what age do height inequalities emerge? J Epidemiol Community Health. 2012;66(2):143-8. PMID:20724285. Heron J, Macleod J, Munafo MR, Melotti R, Lewis G, Tilling K, Hickman M. Patterns of Alcohol Use in Early Adolescence Predict Problem Use at Age 16. Alcohol Alcohol. 2012;47(2):169-77. PMID:22215001. Macdonald-Wallis C, Lawlor D, Palmer T, Tilling K. Multivariate multilevel spline models for parallel growth processes: application to weight and mean arterial pressure in pregnancy. Stat Med. 2012;31(26):3147-6. PMID:22733701. 
 
Title Statistical methods for examining missing data/misclassification 
Description A number of statisticians are working on methods using linkage data to investigate missing data and/or misclassification of exposures/outcomes. This covers a number of different data sources and areas of research including education, mental health and wellbeing 
Type Of Material Improvements to research infrastructure 
Year Produced 2015 
Provided To Others? Yes  
Impact A number of papers have been published including: Cornish R, Tilling K, Boyd A, Macleod J, Van Staa T. Using linkage to electronic primary care records to evaluate recruitment and nonresponse bias in the Avon Longitudinal Study of Parents and Children. Epidemiology. 2015 Jul;26(4):e41-2. doi: 10.1097/EDE.0000000000000288. Cornish RP, Tilling K, Boyd A, Davies A, Macleod J. Using linked educational attainment data to reduce bias due to missing outcome data in estimates of the association between the duration of breastfeeding and IQ at 15 years. Int J Epidemiol. 2015 Jun;44(3):937-45. doi: 10.1093/ije/dyv035. Mars B, Cornish R, Heron J, Boyd A, Crane C, Hawton K, Lewis G, Tilling K, Macleod J, Gunnell D. Using Data Linkage to Investigate Inconsistent Reporting of Self-Harm and Questionnaire Non-Response. Arch Suicide Res. 2016;20(2):113-41. doi: 10.1080/13811118.2015.1033121. Epub 2016 Jan 20. Cornish RP, John A, Boyd A, Tilling K, Macleod J. Defining adolescent common mental disorders using electronic primary care data: a comparison with outcomes measured using the CIS-R. BMJ Open. 2016 Dec 1;6(12):e013167. doi: 10.1136/bmjopen-2016-013167. 
 
Title UK10K Project Dalliance Genome Browser 
Description The UK10K Genome Browser is based on the Biodalliance platform (Down et al., Bioinformatics 2011), designed to facilitate the retrieval of genotype-phenotype association results from the UK10K Cohorts Project (Walter et al, Nature 2015), and their visualisation in the context of different annotation features. 
Type Of Material Physiological assessment or outcome measure 
Provided To Others? No  
Impact Allows researchers to easily access key results from the cohort arm of the UK10K and generate new hypothesis based on this dataset 
URL http://www.uk10k.org/dalliance.html
 
Title Variable Search Tool 
Description A web application has been developed which performs rapid searching of all variables that are readily accessible in the resource. Using this in conjunction with the detailed data dictionary eases discoverability of the ALSPAC data for potential users. This web based app was formally released in May 2018 
Type Of Material Improvements to research infrastructure 
Year Produced 2018 
Provided To Others? Yes  
Impact The release of the tool has facilicated easy searching for variables and is used widely by both internal and external researchers 
URL http://variables.alspac.bris.ac.uk/
 
Title ARIES-Explorer 
Description ARIES-Explorer provides an openly accessible web interface to explore epigenome-wide methylation data from the Accessible Resource for Integrated Epigenomics Studies 
Type Of Material Database/Collection of data 
Year Produced 2013 
Provided To Others? Yes  
Impact Cited in a key review in the field (Mill et al, Nature Reviews Genetics, VOLUME 14 | AUGUST 2013 | 585). 419 unique visitors to the site in its first month of operation. 
URL http://ariesepigenomics.org.uk/ariesexplorer
 
Title Bristol region NOx modelled Air Pollution Dataset 
Description NOx air pollution data was modelled for the ALSPAC catchment area from 1990 to 2018. In conjunction with ALSPAC participant residential and school geocoding database this enables air pollution data exposure to be estimated and linked to participants. Using the ALGAE software ALSPAC can estimate the exposure with critical development periods (e.g. pregnancy trimesters). Directly measured air pollution records have been collected (from local authority deployed air pollution sensors) and these sensor data will be used to calibrate the modelled data. 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact The data will be used in an ALSPAC based epidemiological assessment of the impact of in utero NOx exposure and lung-function outcomes. It is also being shared with collaborators at Imperial (London) for use in an assessment of the impact of availability of greenspace on mental health outcomes. 
 
Title CLOSER harmonised BMI dataset 
Description ALSPAC has contributed to a harmonised dataset through CLOSER which has harmonised data on height, weight and BMI at ages 7, 8, 9, 10, 11 and 17. The data has been lodged with the UK Data Service and can be accessed through a Special License 
Type Of Material Database/Collection of data 
Year Produced 2017 
Provided To Others? Yes  
Impact Has contributed to our understanding of how rates of obesity have changed over the generations and the impact of social inequalities. See here: https://www.closer.ac.uk/research-fund-2/data-harmonisation/harmonising-measures-body-size-body-composition/ for a summary. 
URL http://doi.org/10.5255/UKDA-SN-8208-1
 
Title Creation of synthetic datasets for the Big Data VR Project 
Description Three synthetic datasets were created containing 15,000, 155,000 and 1,555,000 participants. These synthetic datasets retained similar data properties to the original study data they were simulated from. 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact The data was used in a Wellcome funded project to develop visualisation methods in virtual reality (VR) using big biomedical datasets. As the generated data has no ethical-legal constraints associated with it the synthetic datasets can be used for teaching and training purposes without restriction. 
URL https://wellcomeopenresearch.org/articles/2-74/v1
 
Title Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference 
Description Detailed phenotyping is required to deepen our understanding of the biological mechanisms behind genetic associations. In addition, the impact of potentially modifiable risk factors on disease requires analytical frameworks that allow causal inference. We have described the characteristics of Recall-by-Genotype (RbG) as a study design aimed at addressing both these needs. We presented two broad scenarios for the application of RbG: studies using single variants and those using multiple variants. We also considered the efficacy and practicality of the RbG approach, provide a catalogue of UK-based resources for such studies and present an online RbG study planner. 
Type Of Material Data analysis technique 
Year Produced 2017 
Provided To Others? Yes  
Impact First described here:https://www.biorxiv.org/content/early/2017/04/12/124586, then formally here: https://www.nature.com/articles/s41467-018-03109-y 
URL http://www.bristol.ac.uk/integrative-epidemiology/faciliitiesresources/software/
 
Title Geocoded School History dataset for ALSPAC index participants 
Description We have collated information on the schools ALSPAC participants attended from reception (Age 4-5) through to leaving schooling (Age 16-18). We have addressed issues such as schools changing over time (changing name, moving location etc). We have then geo-coded the school address information and assigned this back into the ALSPAC research database. This now allows ALSPAC staff to map environmental exposure data (e.g. air pollution, proximity to fast-food outlets) to individuals based on which school they attended. 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact The schools geo-coding was used to assign NO2 exposure to ALSPAC participants in a more accurate manner as the model was then able to weight exposure based on residential geocoding and schools geocoding. This dataset can be used in future for similar purposes with different envrionmental exposures. 
URL http://www.bristol.ac.uk/alspac/researchers/our-data/environment-data/
 
Title Training dataset for Mendelian Randomisation 
Description Training materials for a Mendelian Randomisation Course using simulated ALSPAC data has been developed by Nic Timpson and Colleagues. The data and all training materials are available for download fro data.bris. The course has been taught around the world 
Type Of Material Database/Collection of data 
Year Produced 2018 
Provided To Others? Yes  
Impact Enables education and facilitates data use without disclosure risk 
URL https://data.bris.ac.uk/data/dataset/2e8d53bcg2yhp26r79zu425cyg
 
Title mQTLdb 
Description mQTLdb is a database of methylation QTL, initially set up for methylation QTL from the ALSPAC-ARIES project 
Type Of Material Database/Collection of data 
Year Produced 2016 
Provided To Others? Yes  
Impact The database is being used by researchers to identify methylation QTL for Mendelian randomization analyses 
URL http://www.mqtldb.org/
 
Description (Epi)Genetics of Puberty and Risky Sexual Behavior (B3077) 
Organisation University at Albany
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description (Epi)Genetics of Puberty and Risky Sexual Behavior (B3077) 
Organisation University at Albany
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description 10,000 hours: Children, Childcare and Developmental Opportunity (2335) 
Organisation Queensland University of Technology (QUT)
Country Australia 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2014
 
Description 24-hour ambulatory measures of blood pressure and their association with cardiac structure and function in adolescents (B2858) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description A Bayesian mixture framework for epigenetics (2441) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description A GWAS of child's ability to cope as measured by SDQ (B2823) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description A Longitudinal Study on the Impact of Stressful Life Events on Obsessive-Compulsive Disorder Symptomatology (2424) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description A Mendelian Randomisation Study of IL-6, Depression and Psychosis in the ALSPAC Birth Cohort (2323) 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary analysis
Impact None Yet
Start Year 2014
 
Description A Mendelian Randomisation study of Skin tone and Vitamin D (2406) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description A Recall by Genotype Study to investigate the role of common TRPA1 variants in acute pain perception. (B3236) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution New Data collection and secondary analysis
Impact None yet
Start Year 2019
 
Description A comprehensive literature review of the genetic variants identified in Cleft Lip with/without Palate (continued title) (B2814) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description A genetic underpinning of Optimism (2539) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description A hypothesis-free approach to identify DNA sequences regulating gene environment interaction (GxE) in programming adult response (B3203) 
Organisation Manchester Metropolitan University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description A meta-analysis of maternal smoking GFI1-CpGs and cardio-metabolic phenotypes in adults (B3097) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description A methylation-based biomarker for alcohol intake in the general population (B2818) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description A methylation-based biomarker for alcohol intake in the general population (B2818) 
Organisation University of California, San Francisco
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description A molecular genetic study of Theory of Mind (2528) 
Organisation McMaster University
Country Canada 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description A molecular test of the Nature of Nurture in the psychosis pathway (B3171) 
Organisation Icahn School of Medicine at Mount Sinai
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description A multi-omics investigation into the metabolic and epigenetic effects of childhood glycemic profile (2370) 
Organisation University of Bath
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description A novel genetic instrument for lifetime smoking indicates that smoking is a casual risk factor for depression and schizophrenia (B3094) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description A prospective examination of the influence of ultra-processed food consumption on measures of adiposity and CVD (B3052) 
Organisation University of Sao Paulo
Country Brazil 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description A study of origins, correlates and determinants of locus of control (2390) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description ADHD and DNA methylation: a repeated measures EWAS (B2749) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description ALSPAC & DataSHIELD in the InterConnect Project. Subproject1: Physical Activity in Pregnancy & Anthropometric Outcomes (B2660) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description ALSPAC MRI-II (B3035) 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution New data collection and secondary analysis
Impact None yet
Start Year 2018
 
Description ALSPAC Proposal - Education and Myopia: A Bi-directional Mendelian Randomisation Study (B2715) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description ALSPAC analysis for ExomeBP consortium (2615) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact none yet
Start Year 2016
 
Description ALSPAC analysis for YGen consortium (2623) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact none yet
Start Year 2016
 
Description ALSPAC and ELSPAC: Pre-birth cohorts with longitudinal data on childhood obesity, respiratory development and neurocognitive abi (B2650) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution New data and secondary analysis
Impact None yet
Start Year 2016
 
Description ALSPAC cohorts National Chlamydia Screening Programme testing patterns (2594) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analyiss
Impact None yet
Start Year 2015
 
Description ALSPAC exome generation (2605) 
Organisation Massachusetts General Hospital
Country United States 
Sector Hospitals 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description ALSPAC exome generation (B2680) 
Organisation Massachusetts General Hospital
Country United States 
Sector Hospitals 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description ALSPAC iPSC bank - (2489) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description ALSPAC in the Digital Age (2588) 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution secondary ANALYSIS
Impact None yet
Start Year 2015
 
Description ALSPAC mGWAS (B2813) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Abnormal metabolic measures in adolescents with pyschotic experiences (2532) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Accuracy of clinical characteristics, biochemical and ultrasound markers in the prediction of pre-eclampsia: an IPD 
Organisation Queen Mary University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Acetaminophen (paracetamol) use during pregnancy and behaviour problems and autism spectrum symptoms in childhood (B2763) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Acetaminophen Exposure in Utero and Subsequent Impact on Female Reproductive Function (B3225) 
Organisation University of Pennsylvania
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Adaptations to Inequality and the Perpetuation of Disadvantages: An Evolutionary Developmental Approach (B3082) 
Organisation University of Washington
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Adolescent and adult mental health outcomes of autism and autistic traits (2622) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact none yet
Start Year 2016
 
Description Adolescent diet and cardiometabolic health (B2798) 
Organisation University of Leeds
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Adult Eating Behaviour Questionnaire in ALSPAC (2496) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution New data collection via questionnaire - subject to funding by collaborator
Collaborator Contribution Seeking funding to collect new data
Impact None yet
Start Year 2015
 
Description Adverse childhood experiences and body composition in adolescence: a cross-cohort comparison (2598) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Adverse childhood experiences and psychopathology: A genetically informative approach (B3218) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Adverse childhood experiences and psychopathology: A propensity score matching approach (B3219) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Adverse life events, inflammation, and trajectories of emotional and behavioural problems in childhood (B2645) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Prevision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2016
 
Description Aetiology of increased birthweight for gestation (2360) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2014
 
Description Age at menarche and lung function: A Mendelian randomisation analysis (2461) 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Age specific BMI SNP effects (SNP effect look up) (B2998) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Ageing Lungs in European Cohorts Project- EWAS on Lung Function (B2909) 
Organisation University of Basel
Country Switzerland 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Agreement in alcohol reporting (as part of ELAStiC) (B2726) 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Air Pollution Risk and Genetic Liability for Autism and ADHD (2538) 
Organisation University of Wisconsin-Madison
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Air pollution data in ALSPAC - documentation (2600) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Alcohol Misuse: Electronic Longitudinal Alcohol Study in Communities (2501) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Alcohol use, breastfeeding and offspring neurodevelopment (B3248) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2019
 
Description Amendment to STELAR Collaboration - Asthma Trajectories From Childhood to Adulthood (B3149) 
Organisation University Hospital Southampton NHS Foundation Trust
Country United Kingdom 
Sector Hospitals 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description An EWAS of Anti-Mullerian Hormone (2454) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description An adult eating questionnaire to measure disinhibition and restraint (B2872) 
Organisation University of Exeter
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution New data collection and secondary analysis
Impact None yet
Start Year 2017
 
Description An analysis of the environments which promote the development of early speech and language skills (2465) 
Organisation North Bristol NHS Trust
Country United Kingdom 
Sector Public 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description An atlas of phenotypic correlations and a correction of multiple testing across human traits and diseases using GWAS summary sta (B2739) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description An ethical and technical framework for linking social media data in UK cohorts (B2934) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description An examination of the association between school engagement at 10-11 yrs and sexual health and behaviours at 21 yrs (2402) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description An investigation into the determinants of fatigue in a population-based cohort of young adults (2408) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description An investigation of maternal risk factors for the development of paediatric obsessive-compulsive disorder (2330) 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2014
 
Description An investigation of the association between substance use in adolescence and mental health using linked data (B3112) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Analysis for Global Lipids Genetics / The Genetic Investigation of Anthropometric Traits (GLG/GIANT) consortia (B2861) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Analysis of DNA Methylation for family trios (B2724) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis and new data
Impact None yet
Start Year 2016
 
Description Analysis of SNP-heritability and co-heritability of adolescent psychotic experiences (2321) 
Organisation Birkbeck, University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2014
 
Description Analysis of SNP-heritability and co-heritability of adolescent psychotic experiences (2321) 
Organisation Birkbeck, University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2014
 
Description Analysis of copy number variation in relation to age at menarche and age at natural menopause (B2978) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Antecedents of Trait Psychological Functioning (2514) 
Organisation Florida State University
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Antecedents of obesity in the ALSPAC cohort: the role of early diet (sugar and fibre), antibiotics and gut bacteria (B2753) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Antenatal Selection Gradients (B2915) 
Organisation Princeton University
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Antenatal Selection and the Parent-Child Gene Environment: Challenging the Nurture/Nature Dichotomy (B2931) 
Organisation Princeton University
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Antibodies to Infectious Agents and Psychiatric Disorders (B3033) 
Organisation Johns Hopkins Medicine
Country United States 
Sector Hospitals 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Apgar scores and long term growth, health ann development (2495) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Application of the joint linear mixed effect IOU model:accounting for autocorrelation and informative dropout (B2747) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Applied epidemiology and the human gut microbiome: evidence for causal effects versus confounded companionship (B3043) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Applying Mendelian randomization to predicting the overall effects of interventions targeting sclerostin (B2646) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Applying causal inference methods to investigate the impact of adverse childhood experiences on psychopathology (B3219) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Applying genetic risk scores for one-carbon micronutrients to Mendelian randomization and epigenome-wide association analyses (B3140) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Appropriate statistical models for multivariate epigenetic data, with focus on prenatal alcohol exposure. (B2745) 
Organisation University College Dublin
Country Ireland 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Are Children with Impaired Vision or Hearing at Greater or Differential Risk of Unintentional Injury? (2348) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2014
 
Description Are Different Face Shapes Related to Different Levels of Blood Pressure? (B3244) 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2019
 
Description Are associations between maternal risk factors and non-syndromic cleft lip and/or palate mediated by cord blood methylation? (B2681) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Are effects of early-life oxidant exposures on asthma risk modified by TRPA1 variants and mediated by TRPA1 methylation? (B2800) 
Organisation Queen Mary University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Are prenatal metabolites, nutrients, and toxins linked to lung function in adolescence via DNA methylation? (2440) 
Organisation University of Memphis
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Are women who experience domestic violence and abuse more likely to seek emergency contraception? (B2770) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Ascertaining direction of causality in associations between smoking, cognition and schizophrenia (2338) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2014
 
Description Assessing Methylome changes across adolescence in gender-related switch of asthma. (B2687) 
Organisation University of Southampton
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis and new data
Impact None yet
Start Year 2016
 
Description Assessing Misreporting of Smoking Behavior Using DNA Methylation (2614) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Assessing causality in associations between cannabis & tobacco use and poor social cognition: A Mendelian randomization study (B2734) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Assessing causality in metabolic systems (B2880) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Assessing causality in the association between maternal pre-pregnancy obesity and child neurodevelopment: observational and mendelian randomization analyses (2534) 
Organisation Center for Research in Environmental Epidemiology
Country Spain 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Assessing the association between screen time and anxiety in UK adolescents: a prospective longitudinal study using the ALSPAC cohort (2551) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Assessing the extent to which disclosure control techniques impact on data utility (2361) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2014
 
Description Assessing the impact of parental smoking on DNA methylation in offspring sex chromosomes (B2833) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Assessing the impact of parental smoking on genetic variation in offspring Y chromosome (B2847) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Assessing the role of martial status on sexual timing, and the association between breast development and sports participation (B3055) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Assessment and harmonisation of cognitive measures in Britsih Cohort Studies (B3185) 
Organisation University College London
Department Centre for Longitudinal Studies
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Assessment of Telomere Length Measurement in ALSPAC DNA 
Organisation University of Leicester
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Association between arterial stiffness of ALSPAC fathers, mothers and blood pressure trajectories of their offspring (2307) 
Organisation Imperial College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2014
 
Description Association between asthma/allergies and depression/anxiety/self harm 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2014
 
Description Association between brain anatomy and genetic risk for mental disorders in healthy volunteers (2399) 
Organisation Medical Research Council (MRC)
Department MRC Centre for Neuropsychiatric Genetics and Genomics
Country United Kingdom 
Sector Public 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Association between dietary measures and later development of psychotic symptoms in the ALSPAC cohort (2482) 
Organisation University of Warwick
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Association between oxytocin genetic variants and mood, personality and addictive behaviour (B2685) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Association between paternal depressogenic cognitive style during pregnancy and offspring cognitive style 18 years later (B2678) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Association between the complexity of written language in childhood and adolescent mental health (B3101) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Association of adolescent physical activity profiles with hip strength at age 25 (B3235) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2019
 
Description Association of atopic illness and raised inflammatory markers in childhood with manic symptoms in young adult life (2345) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None Yet
Start Year 2014
 
Description Association of childhood mental health with adolescent substance abuse (2621) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution secondary analysis
Impact none yet
Start Year 2016
 
Description Association of dietary factors with cardiometabolic health: Possible mediating role of DNA methylation and metabolome (B2769) 
Organisation Korea University
Country Korea, Republic of 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Association of dietary fat intake in infancy and early childhood with serum leptin concentrations and body fat in later life (B3178) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Association of disease genetic risk scores with DNA methylation (2562) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Association of maternal and child BMI with cardio-metabolic health in adolescence via DNA methylation (B2901) 
Organisation Columbia University
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Association of mitochondrial copy number with phenotypes in the UK10K cohort samples (B2662) 
Organisation The Wellcome Trust Sanger Institute
Country United Kingdom 
Sector Charity/Non Profit 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Association of mtDNA SNPs with anthropometric and glycemic traits: integration with the CHARGEmtDNA+ consortium (2442) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Associations between Adolescent Anxiety and Alcohol Use in Young Adulthood (B2799) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Associations between body composition and lung function development up to 16 years of age (B2722) 
Organisation Barcelona Institute for Global Health
Country Spain 
Sector Multiple 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Associations between childhood diet and subsequent puberty timing (B3208) 
Organisation University of Cambridge
Department MRC Epidemiology Unit
Country United Kingdom 
Sector Multiple 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Associations between disordered eating and socioeconomic status in the ALSPAC cohort (B3034) 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Associations between physical activity and polycystic ovary syndrome features in adolescent girls (B3220) 
Organisation McGill University
Country Canada 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Associations between physical activity and polycystic ovary syndrome features in adolescent girls (B3220) 
Organisation University of Cambridge
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Associations of Behaviour Disorders in Childhood and Psychotic-Like Symptoms in Adolescence (2342) 
Organisation University of Hamburg
Country Germany 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2014
 
Description Associations of smoking with education and neurocognition (B2664) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Associations of wellbeing in DNA methylation (B3146) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Assortative mating in the UK population (2546) 
Organisation University of East Anglia
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Asthma and BMI: aetiology of lean mass versus fat mass (B2980) 
Organisation University of Cambridge
Department MRC Biostatistics Unit
Country United Kingdom 
Sector Public 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Autism, sleep, mental health, parent distress and chronic pain in childhood (2332) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2014
 
Description Automation of the DXA Scoliosis Method (DSM) (B2908) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description BBMRI Metabolomics consortium (2589) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description BIOMAP - Genome-Environment Interactions in Inflammatory Skin Disease (B3072) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description BMI gene x activity interactions (B2920) 
Organisation University of Exeter
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Bayesian individual knot point models for modelling growth (2315) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None Yet
Start Year 2014
 
Description Behavioural PheWAS: Alcohol, tobacco and caffeine use in ALSPAC subpopulations (B3037) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Behavioural susceptibility to obesity in young adults: genetic and environmental determinants of eating behaviour (B2806) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Big Data in the Social Sciences: Statistical methods for multi-source high-dimensional data (B3038) 
Organisation University of Tilburg
Country Netherlands 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Biology and media's Effects And Correlations With Dysfunctional Behavior (B2655) 
Organisation Stetson University
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Biomarkers of lead in preschool children: a pilot study (2433) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Birth Cohorts and the Biosocial: ethnographic interventions on the 'life course' (B3102) 
Organisation University College London
Department Anthropology
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution New Data collection and secondary analysis
Impact None yet
Start Year 2018
 
Description Building a longitudinal picture of early life adversity and life course health (2450) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description CLOSER - extension to WP 2: Harmonisation of socio-economic status and qualifications (B2700) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Capacity of the genome and methylome to predict BMI (B3030) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Causal Relationship between variation in DNA methylation and Type 2 Diabetes: linking epigenetic and gene expression evidence (2624) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact none yet
Start Year 2016
 
Description Causal analysis of maternal substance use during pregnancy and offspring neurodevelopmental outcomes (B3010) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Causal relationship between circulating low density lipoprotein C (LDL-C) and the IGF pathway: A Recall by Genotype study in ALS (B2977) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Causal role of NMR metabolites in reading and spelling measures (2463) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Causes and consequences of urinary incontinence in women (B2842) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Cellular phenotyping of Placentas and Prediction of outcomes (B3026) 
Organisation University of Oxford
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Channels behind genetic information and educational achievements (B2995) 
Organisation Max Planck Society
Country Germany 
Sector Charity/Non Profit 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Characterisation of childhood and adolescent "favourable adiposity" alleles identifed in adults (B3230) 
Organisation University of Exeter
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Characterisation of the common and rare genetic architecture of head circumference during childhood and adolescence (2417) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Characterising the psychological and neurobiological alterations associated with APOE-e4 (2447) 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Child PTSD and longitudinal adverse outcomes (2376) 
Organisation University of Bath
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Child neurodevelopmental problems and parent functioning (B3032) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Childhood BMI trajectories and DNA methylation in adolescents from Birth to Twenty and ALSPAC (B3161) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution New Data collection and secondary analysis
Impact None yet
Start Year 2018
 
Description Childhood adversity, DNA methylation, and risk for depression: A longitudinal study of sensitive periods in development (B2758) 
Organisation Massachusetts General Hospital
Country United States 
Sector Hospitals 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Childhood adversity, HPA-axis function, and the vulnerability or resilience to stress-related psychopathology (B3237) 
Organisation University of Manchester
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2019
 
Description Childhood diet and nutrition and respiratory and allergic outcomes: a longitudinal study. (B3053) 
Organisation Queen Mary University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Childhood predictors of inadequate health literacy in young adults (B2802) 
Organisation Keele University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Childhood speech patterns and adolescent psychopathology (B2723) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Children's Body Image and Socioeconomic Status: Antecedents & Outcomes (B3148) 
Organisation University of Sussex
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Children's Psychosocial Development: Meta-analytical Findings Meet Dynamic Panel Models (B2890) 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Chronic Fatigue Syndrome in ALSPAC mothers (2608) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Clarifying the SES-Health Gradient: The Case for an Epigenetic Mechanism (2377) 
Organisation Queen Mary University of London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Cleaning the self-harm data (B2751) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Co-development of sensory activity and mental health symptoms (B3187) 
Organisation University of Reading
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Coffee and cognitive function (B2675) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Cognition as a protective factor in the presence of elevated genetic and environmental risk factors for psychiatric disorder (B2647) 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Cohort Studies: resources for investigating health outcomes using environmental data (B2705) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Cohorts as Platforms for Mental Health research (CaP:MH) (B3060) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Collection of new non-cognitive skill measures in ALSPAC via questionaire (2462) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Collaboration to collect new data via questionnaire
Collaborator Contribution New data collection via questionnaire
Impact None yet
Start Year 2015
 
Description Colocalization analyses (B3180) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Comparing health and health-related outcomes in adolescence between two generations in England (ALSPAC and MCS) (B2925) 
Organisation University of Liverpool
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Comparing outcomes in adults who were looked after or adopted as children (B2887) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Comparison of polygenic risk scores across cohorts (B2815) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Completion of'Eating behaviours: tracking through the lifecourse and impact on chronic disease (B1129). 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Provision of data.
Collaborator Contribution Provision of data.
Impact N/A (proposal in early stages).
Start Year 2011
 
Description Computational Models for the Prediction and Prevention of Child Traumatic Stress (B3110) 
Organisation NYU Langone Medical Center
Country United States 
Sector Hospitals 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Consortium of Metabolomics Studies (COMETS) (B3017) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Contribution of eQTL analysis to international collaboration (B2876) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Cord Blood Methylation and Childhood Asthma, Wheeze and Lung Function (B2718) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Core Support for TwinsUK Cohort (B3064) 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Correlation between enzymatic and NMR creatinine measurements in blood (B3062) 
Organisation University of Groningen
Country Netherlands 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Cortisol dysregulation as a mediator between early stress and cardiometabolic risk (B2923) 
Organisation University of Michigan
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Coventry Reading, Engagement, Self-Belief and Teaching Project (2389) 
Organisation University of Warwick
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Creating a West African BioResource for Nutritional Genetics and Epigenetics (B2996) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Cross-cultural analyses of health-behaviours and metabolite profiles in Adolescence (UK vs. Malaysia) (B3065) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Cumulative adversity, positive childhood home environment, and risk for cardiovascular disease and depression in young adulthood (2494) 
Organisation University at Albany
Department School of Public Health
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact none yet
Start Year 2015
 
Description DNA Methylation in Spastic Type Cerebral Palsy (B3224) 
Organisation Nemours Children's Clinic
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description DNA methylation and brain structure (B3067) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description DNA methylation and hypertension in pregnant women (2517) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description DNA methylation as a biomarker of risk of adverse pregnancy outcomes (B2988) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description DNA methylation characteristics in cord blood after paracetamol exposure during pregnancy (B2717) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description DNA methylation from birth to adolescence in Generation R and ALSPAC (B2860) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description DNA methylation networks: epigenetic changes during development, across generations, and with environmental exposures (B2808) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description DNA methylation predictors of psychosis-like symptoms (B2756) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description DNA methylation profile in children with varying degrees of sun exposure (B2679) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description DNA methylation proxies for blood cell counts (B2750) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description DNA methylation, victimisation and child psychopathology (2359) 
Organisation King's College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2014
 
Description Dairy intake in pregnancy; anthropometry in infancy and childhood 
Organisation Durham University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Defining ADHD and conduct disorder using linked electronic primary care data (B2945) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Defining the characteristics and needs of females with social communication difficulties (2553) 
Organisation University College London
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Defining the mitochondrial DNA genetic bottleneck by studying the inheritance of low-level heteroplasmy between mothers and offspring (2382) 
Organisation Newcastle University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Deployment of SPHERE technology in a segment of the ASLPAC cohort (2628) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact none yet
Start Year 2016
 
Description Depot specific effect of pre-pubertal IGF-II on post pubertal fat distribution in ALSPAC cohort (B2840) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Derivation of a clinical prediction rule for the diagnosis of asthma (B2830) 
Organisation University of Edinburgh
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Description of blood count data, and associations of adiposity and insulin with blood counts (B3103) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Developing and validating a mathematical model to calculate and predict body mass index (BMI) and obesity in youth (B2757) 
Organisation Concordia University
Country Canada 
Sector Academic/University 
PI Contribution Data prevision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Developing novel online cognitive tests of spatial perception and memory for use in UK population cohorts (2419) 
Organisation Cardiff University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Development of Caetano's discontinuity endogeneity test and application to the effect of vegetarianism on health (B3073) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Development of a multilevel and mixture-model framework for modelling epigenetic changes over time (2618) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact none yet
Start Year 2016
 
Description Development of an E-health package to reduce self-harm, facilitate help-seeking and improve mental wellbeing in young people (2493) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Development of autoimmunity in the general population (B2940) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Development of portion sizes for 5-10 and 11-17 year old children (19-07-2018 - 13:30:01) (B3150) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Developmental factors influencing lifelong Leydig cell functional capacity in men (2311) 
Organisation University of Nottingham
Country United Kingdom 
Sector Academic/University 
PI Contribution Data Provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2014
 
Description Developmental trajectories of bone mass and associations with markers of pubertal timing (B2999) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2017
 
Description Diagram based analysis of causal systems for understanding the causes of alcohol problems (B2684) 
Organisation University of Glasgow
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Diet and Myopia 
Organisation Aston University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Diet and obesity in childhood comparisons between Isle of Man and Southwest England (2638) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution data provision
Collaborator Contribution secondary analysis
Impact none yet
Start Year 2016
 
Description Dietary patterns and depression in adolescents (2396) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Dietary patterns during pregnancy by cluster analysis and childhood neurodevelopment (2354) 
Organisation Federal University of Rio de Janeiro
Country Brazil 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2014
 
Description Dietary patterns, essential fatty acid status, & self-harm amongst adolescents (B2704) 
Organisation National Institutes of Health (NIH)
Department National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Country United States 
Sector Public 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2016
 
Description Dietary predictors of environmental exposures in pregnancy and childhood (2590) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Dietary zinc intake in the ALSPAC cohort: an investigation of dietary sources and growth outcomes (2373) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Different BMI trajectories to adulthood overweight/obesity and their cardio-metabolic consequences (B3164) 
Organisation Loughborough University
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2018
 
Description Different effects for different people: investigating the impact of the neighbourhoods (B3247) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2019
 
Description Dimensions of Adversity: Deprivation and Threat (2524) 
Organisation University of North Carolina at Chapel Hill
Country United States 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary analysis
Impact None yet
Start Year 2015
 
Description Do 22-23 year olds plan to vote? If so how and why? (2387) 
Organisation University of Bristol
Country United Kingdom 
Sector Academic/University 
PI Contribution Data provision
Collaborator Contribution Secondary Analysis
Impact None yet
Start Year 2015
 
Description Do Genetic Factors influence response to anti-VEGF treatment in age-related macular degeneration (2592) 
Organisation NHS Bristol
Country United Kingdom 
Sector Public 
PI Contribution Data provision